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303 results on '"Liu, Yi‐Chang"'

2. Ten-year epidemiology and risk factors of cytomegalovirus infection in hematopoietic stem cell transplantation patients in Taiwan

Author

Huang, Yi-Che, Hsiao, Fei-Yuan, Guan, Shang-Ting, Yao, Ming, Liu, Chia-Jen, Chen, Tzu-Ting, Lin, Tung-Liang, Liu, Yi-Chang, Chen, Tsai-Yun, Hong, Ying-Chung, Ma, Ming-Chun, Tan, Tran-Der, Wang, Chuan-Cheng, Wu, Yi-Ying, Liao, Po-Wei, Wu, Yi-Feng, Chen, Yi-Yang, Yu, Yuan-Bin, Hsieh, Yao-Yu, Lee, Ming-Yang, Liu, Jia-Hau, Lin, Shu-Wen, and Ko, Bor-Sheng

Published
2024
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3. Incidence and predictors of idiopathic pneumonia syndrome in hematopoietic stem cell transplant patients: a nationwide registry study

Author

Liu, Michael A., Lee, Chien-Chang, Phung, Quan, Dao, Quynh-Lan, Tehrani, Babak, Yao, Ming, Li, Chi-Cheng, Wu, Kang-Hsi, Chen, Tsung-Chih, Gau, Jyh-Pyng, Li, Sin-Syue, Wang, Po-Nan, Liu, Yi-Chang, Wang, Tso-Fu, Chiou, Lun-Wei, Lee, Ming-Yang, Yu, Ming-Sun, Wang, Chuan-Cheng, Lin, Shih-Chiang, Chen, Yeu-Chin, Chao, Tsu-Yi, Ma, Ming-Chun, Chen, Chih-Cheng, and Chang, Hsiu-Hao

Published
2022
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6. NOVEL-1st: an observational study to assess the safety and efficacy of nilotinib in newly diagnosed patients with Philadelphia chromosome-positive chronic myeloid leukemia in chronic phase in Taiwan

Author

Hwang, Wen-Li, Chen, Tsung-Chih, Lin, Hsuan-Yu, Chang, Ming-Chih, Hsiao, Pei-Ching, Bai, Li-Yuan, Kuo, Ching-Yuan, Chen, Yeu-Chin, Liu, Ta-Chih, Gau, Jyh-Pyng, Wang, Po-Nan, Hwang, Wei-Shou, Kuo, Ming-Chung, Liu, Chun-Yu, Liu, Yi-Chang, Ma, Ming-Chun, Su, Nai-Wen, Wang, Chuan-Cheng, Wu, Yi-Ying, Yao, Ming, Yeh, Su-Peng, Cheng, Hao-Wei, Lee, Yee-Ming, Ku, Fan-Chen, and Tang, Jih-Luh

Published
2022
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10. Frontoparietal and salience network synchronizations during nonsymbolic magnitude processing predict brain age and mathematical performance in youth.

Author

Ng, Chan‐Tat, Huang, Po‐Hsien, Cho, Yi‐Cheng, Lee, Pei‐Hong, Liu, Yi‐Chang, and Chang, Ting‐Ting

Subjects
MACHINE learning, FRONTOPARIETAL network, SALIENCE network, AGE, MATHEMATICAL ability, ACALCULIA
Abstract

The development and refinement of functional brain circuits crucial to human cognition is a continuous process that spans from childhood to adulthood. Research increasingly focuses on mapping these evolving configurations, with the aim to identify markers for functional impairments and atypical development. Among human cognitive systems, nonsymbolic magnitude representations serve as a foundational building block for future success in mathematical learning and achievement for individuals. Using task‐based frontoparietal (FPN) and salience network (SN) features during nonsymbolic magnitude processing alongside machine learning algorithms, we developed a framework to construct brain age prediction models for participants aged 7–30. Our study revealed differential developmental profiles in the synchronization within and between FPN and SN networks. Specifically, we observed a linear increase in FPN connectivity, concomitant with a decline in SN connectivity across the age span. A nonlinear U‐shaped trajectory in the connectivity between the FPN and SN was discerned, revealing reduced FPN‐SN synchronization among adolescents compared to both pediatric and adult cohorts. Leveraging the Gradient Boosting machine learning algorithm and nested fivefold stratified cross‐validation with independent training datasets, we demonstrated that functional connectivity measures of the FPN and SN nodes predict chronological age, with a correlation coefficient of.727 and a mean absolute error of 2.944 between actual and predicted ages. Notably, connectivity within the FPN emerged as the most contributing feature for age prediction. Critically, a more matured brain age estimate is associated with better arithmetic performance. Our findings shed light on the intricate developmental changes occurring in the neural networks supporting magnitude representations. We emphasize brain age estimation as a potent tool for understanding cognitive development and its relationship to mathematical abilities across the critical developmental period of youth. Practitioner Points: This study investigated the prolonged changes in the brain's architecture across childhood, adolescence, and adulthood, with a focus on task‐state frontoparietal and salience networks.Distinct developmental pathways were identified: frontoparietal synchronization strengthens consistently throughout development, while salience network connectivity diminishes with age. Furthermore, adolescents show a unique dip in connectivity between these networks.Leveraging advanced machine learning methods, we accurately predicted individuals' ages based on these brain circuits, with a more mature estimated brain age correlating with better math skills. [ABSTRACT FROM AUTHOR]

Published
2024
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11. From Sea to Science: Coral Aquaculture for Sustainable Anticancer Drug Development.

Author

Lin, Hung-Yu, Tsai, Tsen-Ni, Hsu, Kai-Cheng, Hsu, Yu-Ming, Chiang, Lin-Chien, El-Shazly, Mohamed, Chang, Ken-Ming, Lin, Yu-Hsuan, Tu, Shang-Yi, Lin, Tony Eight, Du, Ying-Chi, Liu, Yi-Chang, and Lu, Mei-Chin

Abstract

Marine natural products offer immense potential for drug development, but the limited supply of marine organisms poses a significant challenge. Establishing aquaculture presents a sustainable solution for this challenge by facilitating the mass production of active ingredients while reducing our reliance on wild populations and harm to local environments. To fully utilize aquaculture as a source of biologically active products, a cell-free system was established to target molecular components with protein-modulating activity, including topoisomerase II, HDAC, and tubulin polymerization, using extracts from aquaculture corals. Subsequent in vitro studies were performed, including MTT assays, flow cytometry, confocal microscopy, and Western blotting, along with in vivo xenograft models, to verify the efficacy of the active extracts and further elucidate their cytotoxic mechanisms. Regulatory proteins were clarified using NGS and gene modification techniques. Molecular docking and SwissADME assays were performed to evaluate the drug-likeness and pharmacokinetic and medicinal chemistry-related properties of the small molecules. The extract from Lobophytum crassum (LCE) demonstrated potent broad-spectrum activity, exhibiting significant inhibition of tubulin polymerization, and showed low IC50 values against prostate cancer cells. Flow cytometry and Western blotting assays revealed that LCE induced apoptosis, as evidenced by the increased expression of apoptotic protein-cleaved caspase-3 and the populations of early and late apoptotic cells. In the xenograft tumor experiments, LCE significantly suppressed tumor growth and reduced the tumor volume (PC3: 43.9%; Du145: 49.2%) and weight (PC3: 48.8%; Du145: 7.8%). Additionally, LCE inhibited prostate cancer cell migration, and invasion upregulated the epithelial marker E-cadherin and suppressed EMT-related proteins. Furthermore, LCE effectively attenuated TGF-β-induced EMT in PC3 and Du145 cells. Bioactivity-guided fractionation and SwissADME validation confirmed that LCE's main component, 13-acetoxysarcocrassolide (13-AC), holds greater potential for the development of anticancer drugs. [ABSTRACT FROM AUTHOR]

Published
2024
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12. Genomic insights into the formation of human populations in East Asia

Author

Wang, Chuan-Chao, Yeh, Hui-Yuan, Popov, Alexander N., Zhang, Hu-Qin, Matsumura, Hirofumi, Sirak, Kendra, Cheronet, Olivia, Kovalev, Alexey, Rohland, Nadin, Kim, Alexander M., Mallick, Swapan, Bernardos, Rebecca, Tumen, Dashtseveg, Zhao, Jing, Liu, Yi-Chang, Liu, Jiun-Yu, and Mah, Matthew

Subjects
East Asia -- Demographic aspects, Genomics -- Research, Genetic research, Human population genetics -- Research, Environmental issues, Science and technology, Zoology and wildlife conservation
Abstract

The deep population history of East Asia remains poorly understood owing to a lack of ancient DNA data and sparse sampling of present-day people.sup.1,2. Here we report genome-wide data from 166 East Asian individuals dating to between 6000 bc and ad 1000 and 46 present-day groups. Hunter-gatherers from Japan, the Amur River Basin, and people of Neolithic and Iron Age Taiwan and the Tibetan Plateau are linked by a deeply splitting lineage that probably reflects a coastal migration during the Late Pleistocene epoch. We also follow expansions during the subsequent Holocene epoch from four regions. First, hunter-gatherers from Mongolia and the Amur River Basin have ancestry shared by individuals who speak Mongolic and Tungusic languages, but do not carry ancestry characteristic of farmers from the West Liao River region (around 3000 bc), which contradicts theories that the expansion of these farmers spread the Mongolic and Tungusic proto-languages. Second, farmers from the Yellow River Basin (around 3000 bc) probably spread Sino-Tibetan languages, as their ancestry dispersed both to Tibet--where it forms approximately 84% of the gene pool in some groups--and to the Central Plain, where it has contributed around 59-84% to modern Han Chinese groups. Third, people from Taiwan from around 1300 bc to ad 800 derived approximately 75% of their ancestry from a lineage that is widespread in modern individuals who speak Austronesian, Tai-Kadai and Austroasiatic languages, and that we hypothesize derives from farmers of the Yangtze River Valley. Ancient people from Taiwan also derived about 25% of their ancestry from a northern lineage that is related to, but different from, farmers of the Yellow River Basin, which suggests an additional north-to-south expansion. Fourth, ancestry from Yamnaya Steppe pastoralists arrived in western Mongolia after around 3000 bc but was displaced by previously established lineages even while it persisted in western China, as would be expected if this ancestry was associated with the spread of proto-Tocharian Indo-European languages. Two later gene flows affected western Mongolia: migrants after around 2000 bc with Yamnaya and European farmer ancestry, and episodic influences of later groups with ancestry from Turan. Genome-wide data from 166 East Asian individuals dating to between 6000 bc and ad 1000 and from 46 present-day groups provide insights into the histories of mixture and migration of human populations in East Asia., Author(s): Chuan-Chao Wang [sup.1] [sup.2] [sup.3] [sup.4] , Hui-Yuan Yeh [sup.5] , Alexander N. Popov [sup.6] , Hu-Qin Zhang [sup.7] , Hirofumi Matsumura [sup.8] , Kendra Sirak [sup.2] [sup.9] , [...]

Published
2021
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13. Htm1p-Pdi1p is a folding-sensitive mannosidase that marks N-glycoproteins for ER-associated protein degradation.

Author

Liu, Yi-Chang, Fujimori, Danica, and Weissman, Jonathan

Subjects
ER quality control, ERAD, N-glycoprotein, mannosidase, Endoplasmic Reticulum-Associated Degradation, Mannosidases, Protein Disulfide-Isomerases, Yeasts
Abstract

Our understanding of how the endoplasmic reticulum (ER)-associated protein degradation (ERAD) machinery efficiently targets terminally misfolded proteins while avoiding the misidentification of nascent polypeptides and correctly folded proteins is limited. For luminal N-glycoproteins, demannosylation of their N-glycan to expose a terminal α1,6-linked mannose is necessary for their degradation via ERAD, but whether this modification is specific to misfolded proteins is unknown. Here we report that the complex of the mannosidase Htm1p and the protein disulfide isomerase Pdi1p (Htm1p-Pdi1p) acts as a folding-sensitive mannosidase for catalyzing this first committed step in Saccharomyces cerevisiae We reconstitute this step in vitro with Htm1p-Pdi1p and model glycoprotein substrates whose structural states we can manipulate. We find that Htm1p-Pdi1p is a glycoprotein-specific mannosidase that preferentially targets nonnative glycoproteins trapped in partially structured states. As such, Htm1p-Pdi1p is suited to act as a licensing factor that monitors folding in the ER lumen and preferentially commits glycoproteins trapped in partially structured states for degradation.

Published
2016

14. The Prognosis Performance of a Neutrophil- and Lymphocyte-Associated Gene Mutation Score in a Head and Neck Cancer Cohort

Author

Yeh, Tsung-Jang, primary, Wang, Hui-Ching, additional, Cho, Shih-Feng, additional, Wu, Chun-Chieh, additional, Hsieh, Tzu-Yu, additional, Huang, Chien-Tzu, additional, Wang, Min-Hong, additional, Chuang, Tzer-Ming, additional, Gau, Yuh-Ching, additional, Du, Jeng-Shiun, additional, Liu, Yi-Chang, additional, Hsiao, Hui-Hua, additional, Pan, Mei-Ren, additional, Chen, Li-Tzong, additional, and Moi, Sin-Hua, additional

Published
2023
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15. Heterogeneity of Phase II Enzyme Ligands on Controlling the Progression of Human Gastric Cancer Organoids as Stem Cell Therapy Model

Author

Wu, Deng-Chyang, primary, Ku, Chia-Chen, additional, Pan, Jia-Bin, additional, Wuputra, Kenly, additional, Yang, Ya-Han, additional, Liu, Chung-Jung, additional, Liu, Yi-Chang, additional, Kato, Kohsuke, additional, Saito, Shigeo, additional, Lin, Ying-Chu, additional, Chong, Inn-Wen, additional, Hsiao, Michael, additional, Hu, Huang-Ming, additional, Kuo, Chao-Hung, additional, Kuo, Kung-Kai, additional, Lin, Chang-Shen, additional, and Yokoyama, Kazunari K., additional

Published
2023
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17. The incidence and risk factors of hepatic veno-occlusive disease after hematopoietic stem cell transplantation in Taiwan

Author

Lee, Chien-Chang, Chang, Hsiu-Hao, Lu, Meng-Yao, Yang, Yung-Li, Chou, Shu-Wei, Lin, Dong-Tsamn, Jou, Shiann-Tarng, Yao, Ming, Li, Chi-Cheng, Yeh, Su-Peng, Chen, Mei-Hui, Gau, Jyh-Pyng, Li, Sin-Syue, Wang, Po-Nan, Liu, Yi-Chang, Wang, Tso-Fu, Tan, Tran-Der, Lee, Ming-Yang, Yu, Ming-Sun, Wang, Chuan-Cheng, Lin, Shih-Chiang, Chen, Yeu-Chin, Su, Yung-Cheng, Su, Ko-Ying, and Lin, Kai-Hsin

Published
2019
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19. High G9a Expression in DLBCL and Its Inhibition by Niclosamide to Induce Autophagy as a Therapeutic Approach

Author

Hsu, Chin-Mu, primary, Chang, Kung-Chao, additional, Chuang, Tzer-Ming, additional, Chu, Man-Ling, additional, Lin, Pei-Wen, additional, Liu, Hsiao-Sheng, additional, Kao, Shih-Yu, additional, Liu, Yi-Chang, additional, Huang, Chien-Tzu, additional, Wang, Min-Hong, additional, Yeh, Tsung-Jang, additional, Gau, Yuh-Ching, additional, Du, Jeng-Shiun, additional, Wang, Hui-Ching, additional, Cho, Shih-Feng, additional, Hsiao, Chi-En, additional, Tsai, Yuhsin, additional, Hsiao, Samuel Yien, additional, Hung, Li-Chuan, additional, Yen, Chia-Hung, additional, and Hsiao, Hui-Hua, additional

Published
2023
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20. Clinical Trial on the Safety and Tolerability of Personalized Cancer Vaccines Using Human Platelet Lysate-Induced Antigen-Presenting Cells

Author

Koya, Terutsugu, primary, Yoshida, Kenichi, additional, Togi, Misa, additional, Niida, Yo, additional, Togi, Sumihito, additional, Ura, Hiroki, additional, Mizuta, Shuichi, additional, Kato, Tomohisa, additional, Yamada, Sohsuke, additional, Shibata, Takeo, additional, Liu, Yi-Chang, additional, Yuan, Shyng-Shiou, additional, Wu, Deng-Chyang, additional, Kobayashi, Hirohito, additional, Utsugisawa, Taiju, additional, Kanno, Hitoshi, additional, and Shimodaira, Shigetaka, additional

Published
2023
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22. Exploration of anti‐leukemic effect of soft coral‐derived 13‐acetoxysarcocrassolide: Induction of apoptosis via oxidative stress as a potent inhibitor of heat shock protein 90 and topoisomerase II

Author

Chin, Hsien‐Kuo, primary, Lu, Mei‐Chin, additional, Hsu, Kai‐Cheng, additional, El‐Shazly, Mohamed, additional, Tsai, Tsen‐Ni, additional, Lin, Tzu‐Yung, additional, Shih, Shou‐Ping, additional, Lin, Tony Eight, additional, Wen, Zhi‐Hong, additional, Yang, Yu‐Chen S. H., additional, and Liu, Yi‐Chang, additional

Published
2023
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23. Independent Signaling of Hepatoma Derived Growth Factor and Tumor Necrosis Factor-Alpha in Human Gastric Cancer Organoids Infected by Helicobacter pylori

Author

Wuputra, Kenly, primary, Ku, Chia-Chen, additional, Pan, Jia-Bin, additional, Liu, Chung-Jung, additional, Kato, Kohsuke, additional, Lin, Ying-Chu, additional, Liu, Yi-Chang, additional, Lin, Chang-Shen, additional, Hsiao, Michael, additional, Tai, Ming-Hong, additional, Chong, Inn-Wen, additional, Hu, Huang-Ming, additional, Kuo, Chao-Hung, additional, Wu, Deng-Chyang, additional, and Yokoyama, Kazunari K., additional

Published
2023
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24. Deciphering the Functions of Telomerase Reverse Transcriptase in Head and Neck Cancer

Author

Yeh, Tsung-Jang, primary, Luo, Chi-Wen, additional, Du, Jeng-Shiun, additional, Huang, Chien-Tzu, additional, Wang, Min-Hung, additional, Chuang, Tzer-Ming, additional, Gau, Yuh-Ching, additional, Cho, Shih-Feng, additional, Liu, Yi-Chang, additional, Hsiao, Hui-Hua, additional, Chen, Li-Tzong, additional, Pan, Mei-Ren, additional, Wang, Hui-Ching, additional, and Moi, Sin-Hua, additional

Published
2023
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28. Emodin Ameliorates the Efficacy of Carfilzomib in Multiple Myeloma Cells via Apoptosis and Autophagy

Author

Hsu, Chin-Mu, primary, Yen, Chia-Hung, additional, Wang, Shu-Chen, additional, Liu, Yi-Chang, additional, Huang, Chien-Tzu, additional, Wang, Min-Hong, additional, Chuang, Tzer-Ming, additional, Ke, Ya-Lun, additional, Yeh, Tsung-Jang, additional, Gau, Yuh-Ching, additional, Du, Jeng-Shiun, additional, Wang, Hui-Ching, additional, Cho, Shih-Feng, additional, Tsai, Yuhsin, additional, Hsiao, Chi-En, additional, Hsiao, Samuel Yien, additional, and Hsiao, Hui-Hua, additional

Published
2022
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29. Stem Cell Biomarkers and Tumorigenesis in Gastric Cancer

Author

Wuputra, Kenly, primary, Ku, Chia-Chen, additional, Pan, Jia-Bin, additional, Liu, Chung-Jung, additional, Liu, Yi-Chang, additional, Saito, Shigeo, additional, Kato, Kohsuke, additional, Lin, Ying-Chu, additional, Kuo, Kung-Kai, additional, Chan, Te-Fu, additional, Chong, Inn-Wen, additional, Lin, Chang-Shen, additional, Wu, Deng-Chyang, additional, and Yokoyama, Kazunari K., additional

Published
2022
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31. Revisit of the Association between Cytomegalovirus Infection and Invasive Fungal Infection after Allogeneic Hematopoietic Stem Cell Transplantation: A Real-World Analysis from a High CMV Seroprevalence Area

Author

Yeh, Tsung-Jang, primary, Yang, Ching-I, additional, Huang, Chien-Tzu, additional, Wang, Min-Hung, additional, Chuang, Tzer-Ming, additional, Ke, Ya-Lun, additional, Gau, Yuh-Ching, additional, Du, Jeng-Shiun, additional, Wang, Hui-Ching, additional, Cho, Shih-Feng, additional, Lee, Ching-Ping, additional, Hsu, Chin-Mu, additional, Hsiao, Hui-Hua, additional, and Liu, Yi-Chang, additional

Published
2022
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32. The molecular basis of Htm1-mediated commitment of misfolded glycoproteins to endoplasmic reticulum-associated degradation

Author

Liu, Yi-Chang

Subjects
Biochemistry, ERAD, mannosidase, N-glycoprotein, PDI, protein quality control
Abstract

In eukaryotes, nascent proteins that are destined for the secretory pathway enter the endoplasmic reticulum (ER) in unfolded states and generally leave only after they have reached their native conformation. Protein folding in the ER is challenging and often error-prone. To prevent accumulation of misfolded proteins, the ER uses the ER-associated protein degradation (ERAD) machinery to detect and commit these defective proteins for retrotranslocation to cytosol for degradation via the ubiquitin-proteasome system. Previously, our group and others discovered an ERAD pathway that requires the generation of a specific N-glycan structure on misfolded luminal N-glycoproteins to permit their degradation. This N-glycan degradation signal can potentially serve as a mark to flag the defective states of the attached protein, but whether the generation of this N-glycan degradation signal is directly connected to the folding state of the attached protein has remained unknown.My thesis research work is focused on characterization of Htm1p, the mannosidase that is responsible for generating this N-glycan signal in Saccharomyces cerevisiae. Utilizing an in vitro reconstitution system of Htm1p in complex with its interacting partner, Pdi1p, and glycoprotein substrates whose structures can be closely manipulated, I find that unlike other members of the same mannosidase family, Htm1p-Pdi1p is a glycoprotein-specific mannosidase that has little activity against free glycan. I find that Htm1p-Pdi1p targets intrinsically and artificially misfolded proteins but not their native counterparts. Most importantly, I find that Htm1p-Pdi1p differentiates detailed folding states of misfolded proteins and preferentially acts on partially folded proteins to globally unfolded species. I further find that by forming a tight complex with Pdi1p, Htm1p blocks the intrinsic oxidoreductase function of Pdi1p but keeping the chaperone activity, suggesting a potential mechanism of how the Htm1p-Pdi1p complex recognizes misfolded proteins. In summary, this work demonstrates the tight correlation between the generation of the N-glycan degradation signal and the folding state of the attached protein, opening a future direction to investigate how the ER tells the bad from the good.

Published
2016

34. The Cost-Effectiveness Analysis of Transplant-Ineligible Myeloma Patients with Bortezomib plus Thalidomide plus Dexamethasone (VTD) or Bortezomib plus Melphalan plus Prednisolone (VMP) Treatment in Southern Taiwan

Author

Du, Jeng-Shiun, primary, Kuo, Yi-Chun, additional, Shi, Hon-Yi, additional, Wang, Ming-Chung, additional, Wang, Li-Ying, additional, Chuang, Tzer-Ming, additional, Ke, Ya-Lun, additional, Yeh, Tsung-Jang, additional, Gau, Yu-Ching, additional, Wang, Hui-Ching, additional, Cho, Shih-Feng, additional, Hsiao, Samuel Yien, additional, Liu, Yi-Chang, additional, Hsu, Chin-Mu, additional, and Hsiao, Hui-Hua, additional

Published
2022
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35. Generation of Human Stomach Cancer iPSC-Derived Organoids Induced by Helicobacter pylori Infection and Their Application to Gastric Cancer Research

Author

Ku, Chia-Chen, primary, Wuputra, Kenly, additional, Pan, Jia-Bin, additional, Li, Chia-Pei, additional, Liu, Chung-Jung, additional, Liu, Yi-Chang, additional, Saito, Shigeo, additional, Chan, Te-Fu, additional, Lin, Chang-Shen, additional, Wu, Deng-Chyang, additional, and Yokoyama, Kazunari K., additional

Published
2022
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36. Clustering of Chromatin Remodeling Enzymes Predicts Prognosis and Clinical Benefit of Therapeutic Strategy in Pancreatic Cancer

Author

Wang, Hui-Ching, primary, Shih, Hsiang-Yao, additional, Wu, Chun-Chieh, additional, Chen, Li-Tzong, additional, Luo, Chi-Wen, additional, Liu, Yi-Chang, additional, Du, Jeng-Shiun, additional, Huang, Min-Chin, additional, Su, Yung-Yeh, additional, Chen, Huan-Da, additional, Hsiao, Hui-Hua, additional, Moi, Sin-Hua, additional, and Pan, Mei-Ren, additional

Published
2022
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41. Is it reasonable for the use of Rh‐ee blood? A hospital‐based survey from a southern medical center in Taiwan

Author

Hsiao, Hui‐Hua, primary, Yeh, Chi‐Jung, additional, Ting, Shuo‐Chun, additional, Chuang, Tzer‐Ming, additional, Ke, Ya‐Lun, additional, Yeh, Tsung‐Jang, additional, Gau, Yu‐Chin, additional, Du, Jeng‐Shiun, additional, Hsiao, Chi‐En, additional, Wang, Hui‐Ching, additional, Cho, Shih‐Feng, additional, Hsu, Chin‐Mu, additional, and Liu, Yi‐Chang, additional

Published
2021
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43. Validation of a Post-Transplant Lymphoproliferative Disorder Risk Prediction Score and Derivation of a New Prediction Score Using a National Bone Marrow Transplant Registry Database

Author

Lee, Chien-Chang, primary, Hsu, Tzu-Chun, additional, Kuo, Chia-Chih, additional, Liu, Michael A., additional, Abdelfattah, Ahmed M., additional, Chang, Chia-Na, additional, Yao, Ming, additional, Li, Chi-Cheng, additional, Wu, Kang-Hsi, additional, Chen, Tsung-Chih, additional, Gau, Jyh-Pyng, additional, Wang, Po-Nan, additional, Liu, Yi-Chang, additional, Chiou, Lun-Wei, additional, Lee, Ming-Yang, additional, Li, Sin-Syue, additional, Chao, Tsu-Yi, additional, Jou, Shiann-Tarng, additional, and Chang, Hsiu-Hao, additional

Published
2021
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44. Low Geriatric Nutritional Risk Index Is Associated with Poorer Prognosis in Elderly Diffuse Large B-Cell Lymphoma Patients Unfit for Intensive Anthracycline-Containing Therapy: A Real-World Study

Author

Chuang, Tzer-Ming, primary, Liu, Yi-Chang, additional, Hsiao, Hui-Hua, additional, Wang, Hui-Ching, additional, Du, Jeng-Shiun, additional, Yeh, Tsung-Jang, additional, Gau, Yuh-Ching, additional, Ke, Ya-Lun, additional, Yang, Ching-I, additional, Lee, Ching-Ping, additional, Hsu, Chin-Mu, additional, and Cho, Shih-Feng, additional

Published
2021
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45. Progression Risk Score Estimation Based on Immunostaining Data in Oral Cancer Using Unsupervised Hierarchical Clustering Analysis: A Retrospective Study in Taiwan

Author

Wang, Hui-Ching, primary, Chan, Leong-Perng, additional, Wu, Chun-Chieh, additional, Hsiao, Hui-Hua, additional, Liu, Yi-Chang, additional, Cho, Shih-Feng, additional, Du, Jeng-Shiun, additional, Liu, Ta-Chih, additional, Yang, Cheng-Hong, additional, Pan, Mei-Ren, additional, and Moi, Sin-Hua, additional

Published
2021
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46. Poor Prognosis of Diffuse Large B-Cell Lymphoma with Hepatitis C Infection

Author

Tsai, Yu-Fen, primary, Liu, Yi-Chang, additional, Yang, Ching-I, additional, Chuang, Tzer-Ming, additional, Ke, Ya-Lun, additional, Yeh, Tsung-Jang, additional, Gau, Yuh-Ching, additional, Du, Jeng-Shiun, additional, Wang, Hui-Ching, additional, Cho, Shih-Feng, additional, Hsu, Chin-Mu, additional, Wu, Pey-Fang, additional, Huang, Ching-I, additional, Huang, Chung-Feng, additional, Yu, Ming-Lung, additional, Dai, Chia-Yen, additional, and Hsiao, Hui-Hua, additional

Published
2021
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48. Phase I study of ADI‐PEG20 plus low‐dose cytarabine for the treatment of acute myeloid leukemia

Author

Tsai, Hui‐Jen, primary, Hsiao, Hui‐Hua, additional, Hsu, Ya‐Ting, additional, Liu, Yi‐Chang, additional, Kao, Hsiao‐Wen, additional, Liu, Ta‐Chih, additional, Cho, Shih‐Feng, additional, Feng, Xiaoxing, additional, Johnston, Amanda, additional, Bomalaski, John S., additional, Kuo, Ming‐Chung, additional, and Chen, Tsai‐Yun, additional

Published
2021
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49. The Overall Efficacy and Outcomes of Metronomic Tegafur-Uracil Chemotherapy on Locally Advanced Head and Neck Squamous Cell Carcinoma: A Real-World Cohort Experience

Author

Yeh, Tsung-Jang, primary, Chan, Leong-Perng, additional, Tsai, Hui-Ting, additional, Hsu, Chin-Mu, additional, Cho, Shih-Feng, additional, Pan, Mei-Ren, additional, Liu, Yi-Chang, additional, Huang, Chih-Jen, additional, Wu, Che-Wei, additional, Du, Jeng-Shiun, additional, and Wang, Hui-Ching, additional

Published
2021
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50. A Marine Terpenoid, Heteronemin, Induces Both the Apoptosis and Ferroptosis of Hepatocellular Carcinoma Cells and Involves the ROS and MAPK Pathways

Author

Chang, Wen-Tsan, primary, Bow, Yung-Ding, additional, Fu, Pei-Jung, additional, Li, Chia-Yang, additional, Wu, Chang-Yi, additional, Chang, Yi-Hua, additional, Teng, Yen-Ni, additional, Li, Ruei-Nian, additional, Lu, Mei-Chin, additional, Liu, Yi-Chang, additional, and Chiu, Chien-Chih, additional

Published
2021
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