203 results on '"Kuniss, Malte"'
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2. Electrophysiology lab efficiency comparison between cryoballoon and point-by-point radiofrequency ablation: a German sub-analysis of the FREEZE Cohort study
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Metzner, Andreas, Straube, Florian, Tilz, Roland R., Kuniss, Malte, Noelker, Georg, Tebbenjohanns, Juergen, Andresen, Dietrich, Wieneke, Heinrich, Stellbrink, Christoph, Franke, Jennifer, Dorwarth, Uwe, Carion, Phuong Lien, Holbrook, Reece, Hochadel, Matthias, Senges, Jochen, Hoffmann, Ellen, and Kuck, Karl-Heinz
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- 2023
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3. The Cost-Effectiveness of First-Line Cryoablation vs First-Line Antiarrhythmic Drugs in Canadian Patients With Paroxysmal Atrial Fibrillation
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Andrade, Jason G., Moss, Joe W.E., Kuniss, Malte, Sadri, Hamid, Wazni, Oussama, Sale, Alicia, Ismyrloglou, Eleni, Chierchia, Gian Battista, Kaplon, Rachelle, Mealing, Stuart, Bainbridge, Jamie, Bromilow, Tom, Lane, Emily, and Khaykin, Yaariv
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- 2024
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4. An economic evaluation of first-line cryoballoon ablation vs antiarrhythmic drug therapy for the treatment of paroxysmal atrial fibrillation from a U.S. Medicare perspective
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Wazni, Oussama, Moss, Joe, Kuniss, Malte, Andrade, Jason, Chierchia, Gian Battista, Mealing, Stuart, Mburu, Waruiru, Sale, Alicia, Kaplon, Rachelle, Ismyrloglou, Eleni, Bromilow, Tom, Lane, Emily, Lewis, Damian, and Reynolds, Matthew R.
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- 2023
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5. Patterns of oral anticoagulant use and outcomes in Asian patients with atrial fibrillation: a post-hoc analysis from the GLORIA-AF Registry
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Abban, Dzifa Wosornu, Abdul, Nasser, Abud, Atilio Marcelo, Adams, Fran, Addala, Srinivas, Adragão, Pedro, Ageno, Walter, Aggarwal, Rajesh, Agosti, Sergio, Agostoni, Piergiuseppe, Aguilar, Francisco, Linares, Julio Aguilar, Aguinaga, Luis, Ahmed, Jameel, Aiello, Allessandro, Ainsworth, Paul, Aiub, Jorge Roberto, Al-Dallow, Raed, Alderson, Lisa, Aldrete Velasco, Jorge Antonio, Alexopoulos, Dimitrios, Manterola, Fernando Alfonso, Aliyar, Pareed, Alonso, David, Alves da Costa, Fernando Augusto, Amado, José, Amara, Walid, Amelot, Mathieu, Amjadi, Nima, Ammirati, Fabrizio, Andrade, Marianna, Andrawis, Nabil, Annoni, Giorgio, Ansalone, Gerardo, Ariani, M.Kevin, Arias, Juan Carlos, Armero, Sébastien, Arora, Chander, Aslam, Muhammad Shakil, Asselman, M., Audouin, Philippe, Augenbraun, Charles, Aydin, S., Ayryanova, Ivaneta, Aziz, Emad, Backes, Luciano Marcelo, Badings, E., Bagni, Ermentina, Baker, Seth H., Bala, Richard, Baldi, Antonio, Bando, Shigenobu, Banerjee, Subhash, Bank, Alan, Esquivias, Gonzalo Barón, Barr, Craig, Bartlett, Maria, Kes, Vanja Basic, Baula, Giovanni, Behrens, Steffen, Bell, Alan, Benedetti, Raffaella, Mazuecos, Juan Benezet, Benhalima, Bouziane, Bergler-Klein, Jutta, Berneau, Jean-Baptiste, Bernstein, Richard A., Berrospi, Percy, Berti, Sergio, Berz, Andrea, Best, Elizabeth, Bettencourt, Paulo, Betzu, Robert, Bhagwat, Ravi, Bhatta, Luna, Biscione, Francesco, Bisignani, Giovanni, Black, Toby, Bloch, Michael J., Bloom, Stephen, Blumberg, Edwin, Bo, Mario, Bøhmer, Ellen, Bollmann, Andreas, Bongiorni, Maria Grazia, Boriani, Giuseppe, Boswijk, D.J., Bott, Jochen, Bottacchi, Edo, Kalan, Marica Bracic, Bradman, Drew, Brautigam, Donald, Breton, Nicolas, Brouwers, P.J.A.M., Browne, Kevin, Cortada, Jordi Bruguera, Bruni, A., Brunschwig, Claude, Buathier, Hervé, Buhl, Aurélie, Bullinga, John, Cabrera, Jose Walter, Caccavo, Alberto, Cai, Shanglang, Caine, Sarah, Calò, Leonardo, Calvi, Valeria, Sánchez, Mauricio Camarillo, Candeias, Rui, Capuano, Vincenzo, Capucci, Alessandro, Caputo, Ronald, Rizo, Tatiana Cárdenas, Cardona, Francisco, Carlos da Costa Darrieux, Francisco, Duarte Vera, Yan Carlos, Carolei, Antonio, Carreño, Susana, Carvalho, Paula, Cary, Susanna, Casu, Gavino, Cavallini, Claudio, Cayla, Guillaume, Celentano, Aldo, Cha, Tae-Joon, Cha, Kwang Soo, Chae, Jei Keon, Chalamidas, Kathrine, Challappa, Krishnan, Chand, Sunil Prakash, Chandrashekar, Harinath, Chartier, Ludovic, Chatterjee, Kausik, Chavez Ayala, Carlos Antero, Cheema, Aamir, Cheema, Amjad, Chen, Lin, Chen, Shih-Ann, Chen, Jyh Hong, Chiang, Fu-Tien, Chiarella, Francesco, Chih-Chan, Lin, Cho, Yong Keun, Choi, Jong-Il, Choi, Dong Ju, Chouinard, Guy, Hoi-Fan Chow, Danny, Chrysos, Dimitrios, Chumakova, Galina, José Roberto, Eduardo Julián, Valenzuela, Chuquiure, Nica, Nicoleta Cindea, Cislowski, David J., Clay, Anthony, Clifford, Piers, Cohen, Andrew, Cohen, Michael, Cohen, Serge, Colivicchi, Furio, Collins, Ronan, Colonna, Paolo, Compton, Steve, Connolly, Derek, Conti, Alberto, Buenostro, Gabriel Contreras, Coodley, Gregg, Cooper, Martin, Coronel, Julian, Corso, Giovanni, Sales, Juan Cosín, Cottin, Yves, Covalesky, John, Cracan, Aurel, Crea, Filippo, Crean, Peter, Crenshaw, James, Cullen, Tina, Darius, Harald, Dary, Patrick, Dascotte, Olivier, Dauber, Ira, Davalos, Vicente, Davies, Ruth, Davis, Gershan, Davy, Jean-Marc, Dayer, Mark, De Biasio, Marzia, De Bonis, Silvana, De Caterina, Raffaele, De Franceschi, Teresiano, de Groot, J.R., De Horta, José, De La Briolle, Axel, Topete, Gilberto de la Pena, Vicenzo de Paola, Angelo Amato, de Souza, Weimar, de Veer, A., De Wolf, Luc, Decoulx, Eric, Deepak, Sasalu, Defaye, Pascal, Del-Carpio Munoz, Freddy, Brkljacic, Diana Delic, Deumite, N. Joseph, Di Legge, Silvia, Diemberger, Igor, Dietz, Denise, Dionísio, Pedro, Dong, Qiang, Rossi dos Santos, Fabio, Dotcheva, Elena, Doukky, Rami, D'Souza, Anthony, Dubrey, Simon, Ducrocq, Xavier, Dupljakov, Dmitry, Duque, Mauricio, Dutta, Dipankar, Duvilla, Nathalie, Duygun, A., Dziewas, Rainer, Eaton, Charles B., Eaves, William, Ebels-Tuinbeek; Clifford Ehrlich, L.A., Eichinger-Hasenauer, Sabine, Eisenberg, Steven J., El Jabali, Adnan, El Shahawy, Mahfouz, Hernandes, Mauro Esteves, Izal, Ana Etxeberria, Evonich, Rudolph, III, Evseeva, Oksana, Ezhov, Andrey, Fahmy, Raed, Fang, Quan, Farsad, Ramin, Fauchier, Laurent, Favale, Stefano, Fayard, Maxime, Fedele, Jose Luis, Fedele, Francesco, Fedorishina, Olga, Fera, Steven R., Gomes Ferreira, Luis Gustavo, Ferreira, Jorge, Ferri, Claudio, Ferrier, Anna, Ferro, Hugo, Finsen, Alexandra, First, Brian, Fischer, Stuart, Fonseca, Catarina, Almeida, Luísa Fonseca, Forman, Steven, Frandsen, Brad, French, William, Friedman, Keith, Friese, Athena, Fruntelata, Ana Gabriela, Fujii, Shigeru, Fumagalli, Stefano, Fundamenski, Marta, Furukawa, Yutaka, Gabelmann, Matthias, Gabra, Nashwa, Gadsbøll, Niels, Galinier, Michel, Gammelgaard, Anders, Ganeshkumar, Priya, Gans, Christopher, Quintana, Antonio Garcia, Gartenlaub, Olivier, Gaspardone, Achille, Genz, Conrad, Georger, Frédéric, Georges, Jean-Louis, Georgeson, Steven, Giedrimas, Evaldas, Gierba, Mariusz, Ortega, Ignacio Gil, Gillespie, Eve, Giniger, Alberto, Giudici, Michael C., Gkotsis, Alexandros, Glotzer, Taya V., Gmehling, Joachim, Gniot, Jacek, Goethals, Peter, Goldbarg, Seth, Goldberg, Ronald, Goldmann, Britta, Golitsyn, Sergey, Gómez, Silvia, Mesa, Juan Gomez, Gonzalez, Vicente Bertomeu, Gonzalez Hermosillo, Jesus Antonio, González López, Víctor Manuel, Gorka, Hervé, Gornick, Charles, Gorog, Diana, Gottipaty, Venkat, Goube, Pascal, Goudevenos, Ioannis, Graham, Brett, Greer, G. Stephen, Gremmler, Uwe, Grena, Paul G., Grond, Martin, Gronda, Edoardo, Grönefeld, Gerian, Gu, Xiang, Torres Torres, Ivett Guadalupe, Guardigli, Gabriele, Guevara, Carolina, Guignier, Alexandre, Gulizia, Michele, Gumbley, Michael, Günther, Albrecht, Ha, Andrew, Hahalis, Georgios, Hakas, Joseph, Hall, Christian, Han, Bing, Han, Seongwook, Hargrove, Joe, Hargroves, David, Harris, Kenneth B., Haruna, Tetsuya, Hayek, Emil, Healey, Jeff, Hearne, Steven, Heffernan, Michael, Heggelund, Geir, Heijmeriks, J.A., Hemels, Maarten, Hendriks, I., Henein, Sam, Her, Sung-Ho, Hermany, Paul, Hernández Del Río, Jorge Eduardo, Higashino, Yorihiko, Hill, Michael, Hisadome, Tetsuo, Hishida, Eiji, Hoffer, Etienne, Hoghton, Matthew, Hong, Kui, Hong, Suk keun, Horbach, Stevie, Horiuchi, Masataka, Hou, Yinglong, Hsing, Jeff, Huang, Chi-Hung, Huckins, David, Hughes, kathy, Huizinga, A., Hulsman, E.L., Hung, Kuo-Chun, Hwang, Gyo-Seung, Ikpoh, Margaret, Imberti, Davide, Ince, Hüseyin, Indolfi, Ciro, Inoue, Shujiro, Irles, Didier, Iseki, Harukazu, Israel, C. Noah, Iteld, Bruce, Iyer, Venkat, Jackson-Voyzey, Ewart, Jaffrani, Naseem, Jäger, Frank, James, Martin, Jang, Sung-Won, Jaramillo, Nicolas, Jarmukli, Nabil, Jeanfreau, Robert J., Jenkins, Ronald D., Sánchez, Carlos Jerjes, Jimenez, Javier, Jobe, Robert, Joen-Jakobsen, Tomas, Jones, Nicholas, Moura Jorge, Jose Carlos, Jouve, Bernard, Jung, Byung Chun, Jung, Kyung Tae, Jung, Werner, Kachkovskiy, Mikhail, Kafkala, Krystallenia, Kalinina, Larisa, Kallmünzer, Bernd, Kamali, Farzan, Kamo, Takehiro, Kampus, Priit, Kashou, Hisham, Kastrup, Andreas, Katsivas, Apostolos, Kaufman, Elizabeth, Kawai, Kazuya, Kawajiri, Kenji, Kazmierski, John F., Keeling, P., Kerr Saraiva, José Francisco, Ketova, Galina, Khaira, Ajit Singh, Khripun, Aleksey, Kim, Doo-Il, Kim, Young Hoon, Kim, Nam Ho, Kim, Dae Kyeong, Kim, Jeong Su, Kim, June Soo, Kim, Ki Seok, Kim, Jin bae, Kinova, Elena, Klein, Alexander, Kmetzo, James J., Kneller, G. Larsen, Knezevic, Aleksandar, Angela Koh, Su Mei, Koide, Shunichi, Kollias, Anastasios, Kooistra, J.A., Koons, Jay, Koschutnik, Martin, Kostis, William J., Kovacic, Dragan, Kowalczyk, Jacek, Koziolova, Natalya, Kraft, Peter, Kragten, Johannes A., Krantz, Mori, Krause, Lars, Krenning, B.J., Krikke, F., Kromhout, Z., Krysiak, Waldemar, Kumar, Priya, Kümler, Thomas, Kuniss, Malte, Kuo, Jen-Yuan, Küppers, Achim, Karla Kurrelmeyer, Kwak, Choong Hwan, Laboulle, Bénédicte, Labovitz, Arthur, Lai, Wen Ter, Lam, Andy, Lam, Yat Yin, Zanetti, Fernando Lanas, Landau, Charles, Landini, Giancarlo, Figueiredo, Estêvão Lanna, Larsen, Torben, Lavandier, Karine, LeBlanc, Jessica, Lee, Moon Hyoung, Lee, Chang-Hoon, Lehman, John, Leitão, Ana, Lellouche, Nicolas, Lelonek, Malgorzata, Lenarczyk, Radoslaw, Lenderink, T., González, Salvador León, Leong-Sit, Peter, Leschke, Matthias, Ley, Nicolas, Li, Zhanquan, Li, Xiaodong, Li, Weihua, Li, Xiaoming, Lichy, Christhoh, Lieber, Ira, Limon Rodriguez, Ramon Horacio, Lin, Hailong, Lip, Gregory Y.H., Liu, Feng, Liu, Hengliang, Esperon, Guillermo Llamas, Navarro, Nassip Llerena, Lo, Eric, Lokshyn, Sergiy, López, Amador, López-Sendón, José Luís, Lorga Filho, Adalberto Menezes, Lorraine, Richard S., Luengas, Carlos Alberto, Luke, Robert, Luo, Ming, Lupovitch, Steven, Lyrer, Philippe, Ma, Changsheng, Ma, Genshan, Madariaga, Irene, Maeno, Koji, Magnin, Dominique, Maid, Gustavo, Mainigi, Sumeet K., Makaritsis, Konstantinos, Malhotra, Rohit, Manning, Rickey, Manolis, Athanasios, Manrique Hurtado, Helard Andres, Mantas, Ioannis, Jattin, Fernando Manzur, Maqueda, Vicky, Marchionni, Niccolo, Ortuno, Francisco Marin, Santana, Antonio Martín, Martinez, Jorge, Maskova, Petra, Hernandez, Norberto Matadamas, Matsuda, Katsuhiro, Maurer, Tillmann, Mauro, Ciro, May, Erik, Mayer, Nolan, McClure, John, McCormack, Terry, McGarity, William, McIntyre, Hugh, McLaurin, Brent, Medina Palomino, Feliz Alvaro, Melandri, Francesco, Meno, Hiroshi, Menzies, Dhananjai, Mercader, Marco, Meyer, Christian, Meyer, Beat J., Miarka, Jacek, Mibach, Frank, Michalski, Dominik, Michel, Patrik, Chreih, Rami Mihail, Mikdadi, Ghiath, Mikus, Milan, Milicic, Davor, Militaru, Constantin, Minaie, Sedi, Minescu, Bogdan, Mintale, Iveta, Mirault, Tristan, Mirro, Michael J., Mistry, Dinesh, Miu, Nicoleta Violeta, Miyamoto, Naomasa, Moccetti, Tiziano, Mohammed, Akber, Nor, Azlisham Mohd, Mollerus, Michael, Molon, Giulio, Mondillo, Sergio, Moniz, Patrícia, Mont, Lluis, Montagud, Vicente, Montaña, Oscar, Monti, Cristina, Moretti, Luciano, Mori, Kiyoo, Moriarty, Andrew, Morka, Jacek, Moschini, Luigi, Moschos, Nikitas, Mügge, Andreas, Mulhearn, Thomas J., Muresan, Carmen, Muriago, Michela, Musial, Wlodzimierz, Musser, Carl W., Musumeci, Francesco, Nageh, Thuraia, Nakagawa, Hidemitsu, Nakamura, Yuichiro, Nakayama, Toru, Nam, Gi-Byoung, Nanna, Michele, Natarajan, Indira, Nayak, Hemal M., Naydenov, Stefan, Nazlić, Jurica, Cristian Nechita, Alexandru, Nechvatal, Libor, Negron, Sandra Adela, Neiman, James, Neuenschwander, Fernando Carvalho, Neves, David, Neykova, Anna, Miguel, Ricardo Nicolás, Nijmeh, George, Nizov, Alexey, Campos, Rodrigo Noronha, Nossan, Janko, Novikova, Tatiana, Nowalany-Kozielska, Ewa, Nsah, Emmanuel, Nunez Fragoso, Juan Carlos, Nurgalieva, Svetlana, Nuyens, Dieter, Nyvad, Ole, Odin de Los Rios Ibarra, Manuel, O'Donnell, Philip, O'Donnell, Martin, Oh, Seil, Oh, Yong Seog, Oh, Dongjin, O'Hara, Gilles, Oikonomou, Kostas, Olivares, Claudia, Oliver, Richard, Ruiz, Rafael Olvera, Olympios, Christoforos, omaszuk-Kazberuk, Anna, Asensi, Joaquín Osca, Jose, eena Padayattil, Padilla Padilla, Francisco Gerardo, Rios, Victoria Padilla, Pajes, Giuseppe, Pandey, Shekhar, Paparella, Gaetano, Paris, F., Park, Hyung Wook, Park, Jong Sung, Parthenakis, Fragkiskos, Passamonti, Enrico, Patel, Rajesh J., Patel, Jaydutt, Patel, Mehool, Patrick, Janice, Jimenez, Ricardo Pavón, Paz, Analía, Pengo, Vittorio, Pentz, William, Pérez, Beatriz, Pérez Ríos, Alma Minerva, Pérez-Cabezas, Alejandro, Perlman, Richard, Persic, Viktor, Perticone, Francesco, Peters, Terri K., Petkar, Sanjiv, Pezo, Luis Felipe, Pflücke, Christian, Pham, David N., Phillips, Roland T., Phlaum, Stephen, Pieters, Denis, Pineau, Julien, Pinter, Arnold, Pinto, Fausto, Pisters, R., Pivac, Nediljko, Pocanic, Darko, Podoleanu, Cristian, Politano, Alessandro, Poljakovic, Zdravka, Pollock, Stewart, Garcéa, Jose Polo, Poppert, Holger, Porcu, Maurizio, Reino, Antonio Pose, Prasad, Neeraj, Précoma, Dalton Bertolim, Prelle, Alessandro, Prodafikas, John, Protasov, Konstantin, Pye, Maurice, Qiu, Zhaohui, Quedillac, Jean-Michel, Raev, Dimitar, Raffo Grado, Carlos Antonio, Rahimi, Sidiqullah, Raisaro, Arturo, Rama, Bhola, Ramos, Ricardo, Ranieri, Maria, Raposo, Nuno, Rashba, Eric, Rauch-Kroehnert, Ursula, Reddy, Ramakota, Renda, Giulia, Reza, Shabbir, Ria, Luigi, Richter, Dimitrios, Rickli, Hans, Rieker, Werner, Vera, Tomas Ripolil, Ritt, Luiz Eduardo, Roberts, Douglas, Briones, Ignacio Rodriguez, Rodriguez Escudero, Aldo Edwin, Pascual, Carlos Rodríguez, Roman, Mark, Romeo, Francesco, Ronner, E., Roux, Jean-Francois, Rozkova, Nadezda, Rubacek, Miroslav, Rubalcava, Frank, Russo, Andrea M., Rutgers, Matthieu Pierre, Rybak, Karin, Said, Samir, Sakamoto, Tamotsu, Salacata, Abraham, Salem, Adrien, Bodes, Rafael Salguero, Saltzman, Marco A., Salvioni, Alessandro, Vallejo, Gregorio Sanchez, Fernández, Marcelo Sanmartín, Saporito, Wladmir Faustino, Sarikonda, Kesari, Sasaoka, Taishi, Sati, Hamdi, Savelieva, Irina, Scala, Pierre-Jean, Schellinger, Peter, Scherr, Carlos, Schmitz, Lisa, Schmitz, Karl-Heinz, Schmitz, Bettina, Schnabel, Teresa, Schnupp, Steffen, Schoeniger, Peter, Schön, Norbert, Schwimmbeck, Peter, Seamark, Clare, Searles, Greg, Seidl, Karl-Heinz, Seidman, Barry, Sek, Jaroslaw, Sekaran, Lakshmanan, Serrati, Carlo, Shah, Neerav, Shah, Vinay, Shah, Anil, Shah, Shujahat, Sharma, Vijay Kumar, Shaw, Louise, Sheikh, Khalid H., Shimizu, Naruhito, Shimomura, Hideki, Shin, Dong-Gu, Shin, Eun-Seok, Shite, Junya, Sibilio, Gerolamo, Silver, Frank, Sime, Iveta, Simmers, Tim A., Singh, Narendra, Siostrzonek, Peter, Smadja, Didier, Smith, David W., Snitman, Marcelo, Filho, Dario Sobral, Soda, Hassan, Sofley, Carl, Sokal, Adam, Oi Yan, Yannie Soo, Sotolongo, Rodolfo, Ferreira de Souza, Olga, Sparby, Jon Arne, Spinar, Jindrich, Sprigings, David, Spyropoulos, Alex C., Stakos, Dimitrios, Steinwender, Clemens, Stergiou, Georgios, Stiell, Ian, Stoddard, Marcus, Stoikov, Anastas, Streb, Witold, Styliadis, Ioannis, Su, Guohai, Su, Xi, Sudnik, Wanda, Sukles, Kai, Sun, Xiaofei, Swart, H., Szavits-Nossan, Janko, Taggeselle, Jens, Takagi, Yuichiro, Singh Takhar, Amrit Pal, Tamm, Angelika, Tanaka, Katsumi, Tanawuttiwat, Tanyanan, Tang, Sherman, Tang, Aylmer, Tarsi, Giovanni, Tassinari, Tiziana, Tayal, Ashis, Tayebjee, Muzahir, Berg, J.M. ten, Tesloianu, Dan, The, Salem H.K., Thomas, Dierk, Timsit, Serge, Tobaru, Tetsuya, Tomasik, Andrzej R., Torosoff, Mikhail, Touze, Emmanuel, Trendafilova, Elina, Tsai, W. Kevin, Tse, Hung Fat, Tsutsui, Hiroshi, Tu, Tian Ming, Tuininga, Ype, Turakhia, Minang, Turk, Samir, Turner, Wayne, Tveit, Arnljot, Tytus, Richard, Valadão, C., van Bergen, P.F.M.M., van de Borne, Philippe, van den Berg, B.J., van der Zwaan, C., Van Eck, M., Vanacker, Peter, Vasilev, Dimo, Vasilikos, Vasileios, Vasilyev, Maxim, Veerareddy, Srikar, Miño; Asok Venkataraman, Mario Vega, Verdecchia, Paolo, Versaci, Francesco, Vester, Ernst Günter, Vial, Hubert, Victory, Jason, Villamil, Alejandro, Vincent, Marc, Vlastaris, Anthony, Dahl, Jürgen vom, Vora, Kishor, Vranian, Robert B., Wakefield, Paul, Wang, Ningfu, Wang, Mingsheng, Wang, Xinhua, Wang, Feng, Wang, Tian, Warner, Alberta L., Watanabe, Kouki, Wei, Jeanne, Weimar, Christian, Weiner, Stanislav, Weinrich, Renate, Wen, Ming-Shien, Wiemer, Marcus, Wiggers, Preben, Wilke, Andreas, Williams, David, Williams, Marcus L., Witzenbichler, Bernhard, Wong, Brian, Lawrence Wong, Ka Sing, Wozakowska-Kaplon, Beata, Wu, Shulin, Wu, Richard C., Wunderlich, Silke, Wyatt, Nell, Wylie, John (Jack), Xu, Yong, Xu, Xiangdong, Yamanoue, Hiroki, Yamashita, Takeshi, Bryan Yan, Ping Yen, Yang, Tianlun, Yao, Jing, Yeh, Kuo-Ho, Yin, Wei Hsian, Yotov, Yoto, Zahn, Ralf, Zarich, Stuart, Zenin, Sergei, Zeuthen, Elisabeth Louise, Zhang, Huanyi, Zhang, Donghui, Zhang, Xingwei, Zhang, Ping, Zhang, Jun, Zhao, Shui Ping, Zhao, Yujie, Zhao, Zhichen, Zheng, Yang, Zhou, Jing, Zimmermann, Sergio, Zini, Andrea, Zizzo, Steven, Zong, Wenxia, Zukerman, L. Steven, Romiti, Giulio Francesco, Corica, Bernadette, Proietti, Marco, Mei, Davide Antonio, Frydenlund, Juliane, Bisson, Arnaud, Olshansky, Brian, Chan, Yi-Hsin, Huisman, Menno V., and Chao, Tze-Fan
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- 2023
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6. Expert opinion on design and endpoints for studies on catheter ablation of atrial fibrillation.
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Lewalter, Thorsten, Blomström‐Lundqvist, Carina, Lakkireddy, Dhanunjaya, Packer, Douglas, Meyer, Ralf, Kuniss, Malte, Ladwig, Karl‐H., Jilek, Clemens, Diener, Hans‐C., Boriani, Giuseppe, Turakhia, Mintu P., Schneider, Steffen, Svennberg, Emma, Albers, Bert, Andrade, Jason G., de Melis, Mirko, and Brachmann, Johannes
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MEDICAL protocols ,DOCUMENTATION ,PATIENT selection ,RESEARCH funding ,MEDICAL personnel ,ABLATION techniques ,CLINICAL trials ,RESEARCH evaluation ,EXPERIMENTAL design ,ARRHYTHMIA ,DISCUSSION ,ATRIAL fibrillation ,RESEARCH methodology ,CATHETER ablation ,EXPERTISE - Abstract
Introduction: Catheter ablation of atrial fibrillation (AF) is frequently studied in randomized trials, observational and registry studies. The aim of this expert opinion is to provide guidance for clinicians and industry regarding the development of future clinical studies on catheter ablation of AF, implement lessons learned from previous studies, and promote a higher degree of consistency across studies. Background: Studies on catheter ablation of AF may benefit from well‐described definitions of endpoints and consistent methodology and documentation of outcomes related to efficacy, safety and cost‐effectiveness. The availably of new, innovative technologies warrants further consideration about their application and impact on study design and the choice of endpoints. Moreover, recent insights gained from AF ablation studies suggest a reconsideration of some methodological aspects. Methods: A panel of clinical experts on catheter ablation of AF and designing and conducting clinical studies developed an expert opinion on the design and endpoints for studies on catheter ablation of AF. Discussions within the expert panel with the aim to reach consensus on predefined topics were based on outcomes reported in the literature and experiences from recent clinical trials. Results: A comprehensive set of recommendations is presented. Key elements include the documentation of clinical AF, medication during the study, repeated ablations and their effect on endpoint assessments, postablation blanking and the choice of rhythm‐related and other endpoints. Conclusion: This expert opinion provides guidance and promotes consistency regarding design of AF catheter ablation studies and identified aspects requiring further research to optimize study design and methodology. Recent insights from studies on catheter ablation of atrial fibrillation (AF) and the availability of new innovative technologies warrant reconsideration of methodological aspects related to study design and the choice and assessment of endpoints. This expert opinion, developed by clinical experts on catheter ablation of AF provides a comprehensive set of recommendations related to these methodological aspects. The aim of this expert opinion is to provide guidance for clinicians and industry regarding the development of clinical studies, implement lessons learned from previous studies, and promote a higher degree of consistency across studies. [ABSTRACT FROM AUTHOR]
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- 2024
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7. Initial rhythm control with cryoballoon ablation vs drug therapy: Impact on quality of life and symptoms
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Pavlovic, Nikola, Chierchia, Gian-Battista, Velagic, Vedran, Hermida, Jean Sylvain, Healey, Stewart, Arena, Giuseppe, Badenco, Nicolas, Meyer, Christian, Chen, Jian, Iacopino, Saverio, Anselme, Frédéric, Dekker, Lukas, Scazzuso, Fernando, Packer, Douglas L, de Asmundis, Carlo, Pitschner, Heinz-Friedrich, Piazza, Fabio Di, Kaplon, Rachelle E, and Kuniss, Malte
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- 2021
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8. Cryoballoon Ablation as Initial Treatment for Atrial Fibrillation: JACC State-of-the-Art Review
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Andrade, Jason G., Wazni, Oussama M., Kuniss, Malte, Hawkins, Nathaniel M., Deyell, Marc W., Chierchia, Gian-Battista, Nissen, Steven, Verma, Atul, Wells, George A., and Turgeon, Ricky D.
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- 2021
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9. Segmental nonocclusive cryoballoon ablation of pulmonary veins and extrapulmonary vein structures: Best practices III
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Aryana, Arash, Su, Wilber, Kuniss, Malte, Okishige, Kaoru, de Asmundis, Carlo, Tondo, Claudio, and Chierchia, Gian-Battista
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- 2021
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10. A danish healthcare-focused economic evaluation of first-line cryoballoon ablation versus antiarrhythmic drug therapy for the treatment of paroxysmal atrial fibrillation.
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Hansen, Morten Lock, Moss, Joe W. E., Tønnesen, Jacob, Johansen, Mette Lundsby, Kuniss, Malte, Ismyrloglou, Eleni, Andrade, Jason, Wazni, Oussama, Mealing, Stuart, Sale, Alicia, Afonso, Daniela, Bromilow, Tom, Lane, Emily, and Chierchia, Gian Battista
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ATRIAL fibrillation ,MYOCARDIAL depressants ,DRUG therapy ,QUALITY-adjusted life years ,QUALITY of life - Abstract
Introduction: Three randomised controlled trials (RCTs) have demonstrated that first-line cryoballoon pulmonary vein isolation decreases atrial tachycardia in patients with symptomatic paroxysmal atrial fibrillation (PAF) compared with antiarrhythmic drugs (AADs). The aim of this study was to develop a cost-effectiveness model (CEM) for first-line cryoablation compared with first-line AADs for the treatment of PAF. The model used a Danish healthcare perspective. Methods: Individual patient-level data from the Cryo-FIRST, STOP AF and EARLY-AF RCTs were used to parameterise the CEM. The model structure consisted of a hybrid decision tree (one-year time horizon) and a Markov model (40-year time horizon, with a three-month cycle length). Health-related quality of life was expressed in quality-adjusted life years (QALYs). Costs and benefits were discounted at 3% per year. Model outcomes were produced using probabilistic sensitivity analysis. Results: First-line cryoablation is dominant, meaning it results in lower costs (-€2,663) and more QALYs (0.18) when compared to first-line AADs. First-line cryoablation also has a 99.96% probability of being cost-effective, at a cost-effectiveness threshold of €23,200 per QALY gained. Regardless of initial treatment, patients were expected to receive ∼ 1.2 ablation procedures over a lifetime horizon. Conclusion: First-line cryoablation is both more effective and less costly (i.e. dominant), when compared with AADs for patients with symptomatic PAF in a Danish healthcare system. [ABSTRACT FROM AUTHOR]
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- 2024
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11. Economic evaluation of first-line cryoballoon ablation versus antiarrhythmic drug therapy for the treatment of paroxysmal atrial fibrillation from an English National Health Service perspective.
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Paisey, John, Moss, Joe, Andrade, Jason, Kuniss, Malte, Wazni, Oussama, Chierchia, Gian Battista, Mealing, Stuart, Ismyrloglou, Eleni, Sale, Alicia, Souter, Maxim, Kaplon, Rachelle, Bromilow, Tom, Lane, Emily, Lewis, Damian, and Todd, Derick
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- 2024
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12. Pulmonary Vein Isolation Followed by Biatrial Ablation of Rotational Activity in Patients with Persistent Atrial Fibrillation: Results of the Cryo-Vest Study
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Weipert, Kay Felix, primary, Hutter, Julie, additional, Kuniss, Malte, additional, Kahle, Patrick, additional, Yogarajah, Joerg, additional, Hain, Andreas, additional, Sperzel, Johannes, additional, Berkowitsch, Alexander, additional, Hamm, Christian W., additional, and Neumann, Thomas, additional
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- 2024
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13. Left atrial roof ablation in patients with persistent atrial fibrillation using the second-generation cryoballoon: benefit or wasted time?
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Kuniss, Malte, Akkaya, Ersan, Berkowitsch, Alexander, Zaltsberg, Sergej, Greiss, Harald, Rechner, Markus, Weipert, Kay, Hain, Andreas, Hamm, Christian W., and Neumann, Thomas
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- 2020
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14. Phrenic Nerve Injury During Cryoballoon-Based Pulmonary Vein Isolation: Results of the Worldwide YETI Registry
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Heeger, Christian-H., Sohns, Christian, Pott, Alexander, Metzner, Andreas, Inaba, Osamu, Straube, Florian, Kuniss, Malte, Aryana, Arash, Miyazaki, Shinsuke, Cay, Serkan, Ehrlich, Joachim R., El-Battrawy, Ibrahim, Martinek, Martin, Saguner, Ardan M., Tscholl, Verena, Yalin, Kivanc, Lyan, Evgeny, Su, Wilber, Papiashvili, Giorgi, Botros, Maichel Sobhy Naguib, Gasperetti, Alessio, Proietti, Riccardo, Wissner, Erik, Scherr, Daniel, Kamioka, Masashi, Makimoto, Hisaki, Urushida, Tsuyoshi, Aksu, Tolga, Chun, Julian K.R., Aytemir, Kudret, Jędrzejczyk-Patej, Ewa, Kuck, Karl-Heinz, Dahme, Tillman, Steven, Daniel, Sommer, Philipp, and Richard Tilz, Roland
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- 2022
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15. The Cost-Effectiveness of First-Line Cryoablation versus First-Line Antiarrhythmic Drugs in Canadian Patients with Paroxysmal Atrial Fibrillation
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Andrade, Jason G., primary, Moss, Joe W.E., additional, Kuniss, Malte, additional, Sadri, Hamid, additional, Wazni, D. Oussama, additional, Sale, Alicia, additional, Ismyrloglou, Eleni, additional, Chierchia, Gian Battista, additional, Kaplon, Rachelle, additional, Mealing, Stuart, additional, Bainbridge, Jamie, additional, Bromilow, Tom, additional, Lane, Emily, additional, and Khaykin, Yaariv, additional
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- 2023
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16. Five-year outcome and predictors of success after second-generation cryoballoon ablation for treatment of symptomatic atrial fibrillation
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Akkaya, Ersan, Berkowitsch, Alexander, Zaltsberg, Sergej, Greiss, Harald, Hamm, Christian W., Sperzel, Johannes, Kuniss, Malte, and Neumann, Thomas
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- 2018
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17. Updated Survey on Interventional Electrophysiology: 5-Year Follow-Up of Infrastructure, Procedures, and Training Positions in Germany
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Eckardt, Lars, Frommeyer, Gerrit, Sommer, Philipp, Steven, Daniel, Deneke, Thomas, Estner, Heidi L., Kriatselis, Charalampos, Kuniss, Malte, Busch, Sonia, Tilz, Roland R., Bonnemeier, Hendrik, von Bary, Christian, Voss, Frederik, Meyer, Christian, Thomas, Dierk, and Neuberger, Hans-Ruprecht
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- 2018
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18. Second-generation cryoballoon ablation as a first-line treatment of symptomatic atrial fibrillation: Two-year outcome and predictors of recurrence after a single procedure
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Akkaya, Ersan, Berkowitsch, Alexander, Zaltsberg, Sergej, Greiss, Harald, Hamm, Christian W., Sperzel, Johannes, Neumann, Thomas, and Kuniss, Malte
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- 2018
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19. Ventrikuläre Extrasystolen und Tachykardien bei strukturell normalem Herz: Idiopathische VES und VT
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Busch, Sonia, Eckardt, Lars, Sommer, Philipp, Meyer, Christian, Bonnemeier, Hendrik, Thomas, Dierk, Neuberger, Hans-Ruprecht, Tilz, Roland Richard, Steven, Daniel, von Bary, Christian, Kuniss, Malte, Voss, Frederic, and Estner, Heidi L.
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- 2019
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20. Remote vs. conventional navigation for catheter ablation of atrial fibrillation: insights from prospective registry data
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van den Bruck, Jan-Hendrik, Sultan, Arian, Lüker, Jakob, Thomas, Dierk, Willems, Stephan, Weinmann, Kai, Kuniss, Malte, Hochadel, Matthias, Senges, Jochen, Andresen, Dietrich, Brachmann, Johannes, Kuck, Karl-Heinz, Tilz, Roland, and Steven, Daniel
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- 2019
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21. How safe are NOACs compared with phenprocoumon after pulmonary vein isolation with the cryoballoon technique using purse-string suture closure?
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Akkaya, Ersan, Berkowitsch, Alexander, Zaltsberg, Sergej, Deubner, Nikolas, Greiss, Harald, Hain, Andreas, Hamm, Christian W., Sperzel, Johannes, Kuniss, Malte, and Neumann, Thomas
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- 2017
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22. Abstract 13915: Cryoballoon Catheter Ablation versus Antiarrhythmic Drug as a First-Line Therapy for Patients With Paroxysmal Atrial Fibrillation: Results of the Cryo-FIRST Study
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Velagic, Vedran, Pavlovic, NIkola, Chierchia, Gian-Battista, Hermida, Jean-Sylvain, Healey, Stewart, Arena, Giuseppe, Badenco, Nicolas, Meyer, Christian, Chen, Jian, Iacopino, Saverio, Anselme, Frederic, and Kuniss, Malte
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- 2020
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23. Abstract 13916: Quality of Life Measured in First-line Therapy for Paroxysmal Atrial Fibrillation: A Comparison Between Cryoballoon Catheter Ablation versus Antiarrhythmic Drug Therapy
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Pavlovic, NIkola, Kuniss, Malte, Velagic, Vedran, Hermida, Jean-Sylvain, Healey, Stewart, Arena, Giuseppe, Badenco, Nicolas, Meyer, Christian, Chen, Jian, Iacopino, Saverio, Anselme, Frederic, and Chierchia, Gian-Battista
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- 2020
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24. Nichtinvasives Mapping zur Katheterablation von Arrhythmien mittels der CardioInsight™ EKG-Weste
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Weipert, Kay, Kuniss, Malte, and Neumann, Thomas
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- 2018
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25. PO-02-006 AN ECONOMIC EVALUATION OF FIRST-LINE CRYOBALLOON ABLATION VERSUS ANTIARRHYTHMIC DRUG THERAPY FOR THE TREATMENT OF PAROXYSMAL ATRIAL FIBRILLATION FROM A UNITED STATES MEDICARE PERSPECTIVE
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Wazni, Oussama M., primary, Moss, Joe, additional, Kuniss, Malte, additional, Andrade, Jason G., additional, Chierchia, Gian B., additional, Mealing, Stuart, additional, mburu, waruiru, additional, Sale, Alicia, additional, Kaplon, Rachelle, additional, Ismyrloglou, Eleni, additional, Bromilow, Tom, additional, Lane, Emily, additional, Lewis, Damian, additional, and Reynolds, Matthew R., additional
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- 2023
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26. A worldwide survey on incidence, management, and prognosis of oesophageal fistula formation following atrial fibrillation catheter ablation: the POTTER-AF study
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Tilz, Roland Richard, primary, Schmidt, Vanessa, additional, Pürerfellner, Helmut, additional, Maury, Philippe, additional, Chun, K R J ulian, additional, Martinek, Martin, additional, Sohns, Christian, additional, Schmidt, Boris, additional, Mandel, Franck, additional, Gandjbakhch, Estelle, additional, Laredo, Mikael, additional, Gunawardene, Melanie Anuscha, additional, Willems, Stephan, additional, Beiert, Thomas, additional, Borlich, Martin, additional, Iden, Leon, additional, Füting, Anna, additional, Spittler, Raphael, additional, Gaspar, Thomas, additional, Richter, Sergio, additional, Schade, Anja, additional, Kuniss, Malte, additional, Neumann, Thomas, additional, Francke, Alexander, additional, Wunderlich, Carsten, additional, Shin, Dong-In, additional, Meininghaus, Dirk Grosse, additional, Foresti, Mike, additional, Bonsels, Marc, additional, Reek, David, additional, Wiegand, Uwe, additional, Bauer, Alexander, additional, Metzner, Andreas, additional, Eckardt, Lars, additional, Popescu, Sorin Ștefan, additional, Krahnefeld, Olaf, additional, Sticherling, Christian, additional, Kühne, Michael, additional, Nguyen, Dinh Quang, additional, Roten, Laurent, additional, Saguner, Ardan M, additional, Linz, Dominik, additional, van der Voort, Pepijn, additional, Mulder, Bart A, additional, Vijgen, Johan, additional, Almorad, Alexandre, additional, Guenancia, Charles, additional, Fauchier, Laurent, additional, Boveda, Serge, additional, Greef, Y De, additional, Da Costa, Antoine, additional, Jais, Pierre, additional, Derval, Nicolas, additional, Milhem, Antoine, additional, Jesel, Laurence, additional, Garcia, Rodrigue, additional, Poty, Hervé, additional, Khoueiry, Ziad, additional, Seitz, Julien, additional, Laborderie, Julien, additional, Mechulan, Alexis, additional, Brigadeau, Francois, additional, Zhao, Alexandre, additional, Saludas, Yannick, additional, Piot, Olivier, additional, Ahluwalia, Nikhil, additional, Martin, Claire, additional, Chen, Jian, additional, Antolic, Bor, additional, Leventopoulos, Georgios, additional, Özcan, Emin Evren, additional, Yorgun, Hikmet, additional, Cay, Serkan, additional, Yalin, Kivanc, additional, Botros, Maichel Sobhy, additional, Mahmoud, Ahmed Taher, additional, Jędrzejczyk-Patej, Ewa, additional, Inaba, Osamu, additional, Okumura, Ken, additional, Ejima, Koichiro, additional, Khakpour, Houman, additional, Boyle, Noel, additional, Catanzaro, John N, additional, Reddy, Vivek, additional, Mohanty, Sanghamitra, additional, Natale, Andrea, additional, Blessberger, Hermann, additional, Yang, Bing, additional, Stevens, Irene, additional, Sommer, Philipp, additional, Veltmann, Christian, additional, Steven, Daniel, additional, Vogler, Julia, additional, Kuck, Karl-Heinz, additional, Merino, José Luis, additional, Keelani, Ahmad, additional, and Heeger, Christian-H, additional
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- 2023
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27. Influence of genetic modifiers on sudden cardiac death cases
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Jenewein, Tina, Neumann, Thomas, Erkapic, Damir, Kuniss, Malte, Verhoff, Marcel A., Thiel, Gerhard, and Kauferstein, Silke
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- 2017
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28. Impact of cryoballoon application abortion due to phrenic nerve injury on reconnection rates: a YETI subgroup analysis
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Heeger, Christian-H, Popescu, Sorin Stefan, Sohns, Christian, Pott, Alexander, Metzner, Andreas, Inaba, Osamu, Straube, Florian, Kuniss, Malte, Aryana, Arash, Miyazaki, Shinsuke, Cay, Serkan, Ehrlich, Joachim R., El-Battrawy, Ibrahim, Martinek, Martin, Saguner, Ardan M., Tscholl, Verena, Yalin, Kivanc, Lyan, Evgeny, Su, Wilber, Papiashvili, Giorgi, Botros, Maichel Sobhy Naguib, Gasperetti, Alessio, Proietti, Riccardo, Wissner, Erik, Scherr, Daniel, Kamioka, Masashi, Makimoto, Hisaki, Urushida, Tsuyoshi, Aksu, Tolga, Chun, Julian K. R., Aytemir, Kudret, Jedrzejczyk-Patej, Ewa, Kuck, Karl-Heinz, Dahme, Tillman, Steven, Daniel, Sommer, Philipp, Tilz, Roland Richard, Heeger, Christian-H, Popescu, Sorin Stefan, Sohns, Christian, Pott, Alexander, Metzner, Andreas, Inaba, Osamu, Straube, Florian, Kuniss, Malte, Aryana, Arash, Miyazaki, Shinsuke, Cay, Serkan, Ehrlich, Joachim R., El-Battrawy, Ibrahim, Martinek, Martin, Saguner, Ardan M., Tscholl, Verena, Yalin, Kivanc, Lyan, Evgeny, Su, Wilber, Papiashvili, Giorgi, Botros, Maichel Sobhy Naguib, Gasperetti, Alessio, Proietti, Riccardo, Wissner, Erik, Scherr, Daniel, Kamioka, Masashi, Makimoto, Hisaki, Urushida, Tsuyoshi, Aksu, Tolga, Chun, Julian K. R., Aytemir, Kudret, Jedrzejczyk-Patej, Ewa, Kuck, Karl-Heinz, Dahme, Tillman, Steven, Daniel, Sommer, Philipp, and Tilz, Roland Richard
- Abstract
Aims Cryoballoon (CB)-based pulmonary vein isolation (PVI) is an effective treatment for atrial fibrillation (AF). The most frequent complication during CB-based PVI is right-sided phrenic nerve injury (PNI) which is leading to premature abortion of the freeze cycle. Here, we analysed reconnection rates after CB-based PVI and PNI in a large-scale population during repeat procedures. Methods and results In the YETI registry, a total of 17 356 patients underwent CB-based PVI in 33 centres, and 731 (4.2%) patients experienced PNI. A total of 111/731 (15.2%) patients received a repeat procedure for treatment of recurrent AF. In 94/111 (84.7%) patients data on repeat procedures were available. A total of 89/94 (94.7%) index pulmonary veins (PVs) have been isolated during the initial PVI. During repeat procedures, 22 (24.7%) of initially isolated index PVs showed reconnection. The use of a double stop technique did non influence the PV reconnection rate (P = 0.464). The time to PNI was 140.5 +/- 45.1 s in patients with persistent PVI and 133.5 +/- 53.8 s in patients with reconnection (P = 0.559). No differences were noted between the two populations in terms of CB temperature at the time of PNI (P = 0.362). The only parameter associated with isolation durability was CB temperature after 30 s of freezing. The PV reconnection did not influence the time to AF recurrence. Conclusion In patients with cryoballon application abortion due to PNI, a high rate of persistent PVI rate was found at repeat procedures. Our data may help to identify the optimal dosing protocol in CB-based PVI procedures.
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- 2023
29. A worldwide survey on incidence, management, and prognosis of oesophageal fistula formation following atrial fibrillation catheter ablation: the POTTER-AF study
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Tilz, Roland Richard; https://orcid.org/0000-0002-0122-7130, Schmidt, Vanessa, Pürerfellner, Helmut, Maury, Philippe; https://orcid.org/0000-0002-4800-1841, Chun, K R Julian, Martinek, Martin; https://orcid.org/0000-0002-8895-8488, Sohns, Christian; https://orcid.org/0000-0003-0490-5862, Schmidt, Boris; https://orcid.org/0000-0001-5347-9906, Mandel, Franck, Gandjbakhch, Estelle; https://orcid.org/0000-0002-4846-5021, Laredo, Mikael; https://orcid.org/0000-0002-7326-2656, Gunawardene, Melanie Anuscha, Willems, Stephan; https://orcid.org/0000-0002-8890-5749, Beiert, Thomas, Borlich, Martin, Iden, Leon, Füting, Anna, Spittler, Raphael, Gaspar, Thomas, Richter, Sergio, Schade, Anja, Kuniss, Malte; https://orcid.org/0000-0002-1593-9657, Neumann, Thomas, Francke, Alexander, Wunderlich, Carsten, Shin, Dong-In, Meininghaus, Dirk Grosse; https://orcid.org/0000-0003-1532-1934, Foresti, Mike, Bonsels, Marc, Reek, David, et al, Saguner, Ardan M; https://orcid.org/0000-0003-1896-0803, Tilz, Roland Richard; https://orcid.org/0000-0002-0122-7130, Schmidt, Vanessa, Pürerfellner, Helmut, Maury, Philippe; https://orcid.org/0000-0002-4800-1841, Chun, K R Julian, Martinek, Martin; https://orcid.org/0000-0002-8895-8488, Sohns, Christian; https://orcid.org/0000-0003-0490-5862, Schmidt, Boris; https://orcid.org/0000-0001-5347-9906, Mandel, Franck, Gandjbakhch, Estelle; https://orcid.org/0000-0002-4846-5021, Laredo, Mikael; https://orcid.org/0000-0002-7326-2656, Gunawardene, Melanie Anuscha, Willems, Stephan; https://orcid.org/0000-0002-8890-5749, Beiert, Thomas, Borlich, Martin, Iden, Leon, Füting, Anna, Spittler, Raphael, Gaspar, Thomas, Richter, Sergio, Schade, Anja, Kuniss, Malte; https://orcid.org/0000-0002-1593-9657, Neumann, Thomas, Francke, Alexander, Wunderlich, Carsten, Shin, Dong-In, Meininghaus, Dirk Grosse; https://orcid.org/0000-0003-1532-1934, Foresti, Mike, Bonsels, Marc, Reek, David, et al, and Saguner, Ardan M; https://orcid.org/0000-0003-1896-0803
- Abstract
AIMS Oesophageal fistula represents a rare but dreadful complication of atrial fibrillation catheter ablation. Data on its incidence, management, and outcome are sparse. METHODS AND RESULTS This international multicentre registry investigates the characteristics of oesophageal fistulae after treatment of atrial fibrillation by catheter ablation. A total of 553 729 catheter ablation procedures (radiofrequency: 62.9%, cryoballoon: 36.2%, other modalities: 0.9%) were performed, at 214 centres in 35 countries. In 78 centres 138 patients [0.025%, radiofrequency: 0.038%, cryoballoon: 0.0015% (P < 0.0001)] were diagnosed with an oesophageal fistula. Peri-procedural data were available for 118 patients (85.5%). Following catheter ablation, the median time to symptoms and the median time to diagnosis were 18 (7.75, 25; range: 0-60) days and 21 (15, 29.5; range: 2-63) days, respectively. The median time from symptom onset to oesophageal fistula diagnosis was 3 (1, 9; range: 0-42) days. The most common initial symptom was fever (59.3%). The diagnosis was established by chest computed tomography in 80.2% of patients. Oesophageal surgery was performed in 47.4% and direct endoscopic treatment in 19.8% and conservative treatment in 32.8% of patients. The overall mortality was 65.8%. Mortality following surgical (51.9%) or endoscopic treatment (56.5%) was significantly lower as compared to conservative management (89.5%) [odds ratio 7.463 (2.414, 23.072) P < 0.001]. CONCLUSION Oesophageal fistula after catheter ablation of atrial fibrillation is rare and occurs mostly with the use of radiofrequency energy rather than cryoenergy. Mortality without surgical or endoscopic intervention is exceedingly high.
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- 2023
30. Impact of intracardiac echocardiography usage on the safety of cryoballoon atrial fibrillation ablation: Subanalysis of the prospective FREEZE cluster cohort study.
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Pongratz, Janis, Kuniss, Malte, Wu, Liqun, Tebbenjohanns, Jürgen, Nölker, Georg, Dorwarth, Uwe, Kuck, Karl‐Heinz, Jochen, Senges, Hoffmann, Ellen, and Straube, Florian
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SURGICAL therapeutics , *CARDIAC surgery , *RELATIVE medical risk , *ATRIAL arrhythmias , *CONFIDENCE intervals , *TRANSESOPHAGEAL echocardiography , *MAJOR adverse cardiovascular events , *ATRIAL fibrillation , *CRYOSURGERY , *CATHETER ablation , *SURGICAL complications , *MANN Whitney U Test , *PATIENT readmissions , *DISEASE incidence , *RISK assessment , *CARDIAC tamponade , *COMPARATIVE studies , *FLUOROSCOPY , *SEX distribution , *DISEASE relapse , *TREATMENT effectiveness , *DESCRIPTIVE statistics , *CHI-squared test , *PULMONARY veins , *ODDS ratio , *STATISTICAL models , *DATA analysis software , *LOGISTIC regression analysis , *SECONDARY analysis , *LEFT heart atrium , *LONGITUDINAL method , *DISEASE risk factors - Abstract
Introduction: Cryoballoon ablation (CBA) aiming at pulmonary vein isolation (PVI) became a standardized atrial fibrillation (AF) ablation procedure. Life‐threatening complications like cardiac tamponade exist. Intracardiac echocardiography (ICE) usage is associated with superior safety in radiofrequency ablation. It is unclear if ICE has an impact on safety of CBA. Methods: The FREEZE Cohort (NCT01360008) subanalysis included patients undergoing "PVI only" CBA. Patients with intraprocedural transesophageal echocardiography were excluded. Group A comprises conventional, group B ICE‐guided CBA. Periprocedural results were compared. Results: From 2011 to 2016, a total of 4189 patients were enrolled, and 1906 (45.5%) were included in this subanalysis, split up in two groups (A: 1066 [55.9%], B: 840 [44.1%]). Group A was younger (60.6 ± 10.8 vs. 62.4 ± 10.5 years, p <.001), with smaller left atria (41 vs. 43 mm, p <.001), and less persistent AF (23.1 vs. 38.1%, p <.001). Procedure, left atrial, and fluoroscopy times were shorter in group A as compared to group B. Dose area product was significantly higher in group A (2911 vs. 2072 cGyxcm2, p <.001). In‐hospital major adverse cerebrovascular and cardiac event rates including two deaths in group A were not different between groups (0.5% vs. 0.1%, p =.18). The rate of total procedural (10.4% vs. 5.1%, p <.001) and major complications (3.2% vs. 1.3%, p <.001) was significantly higher in group A. Cardiac tamponade occurred significantly more frequently in group A (8 [0.8%] vs. 1 [0.1%], p =.046). Independent predictors for major complications were female sex (odds ratio [OR] 2.03, p =.03) and non‐ICE usage (OR 2.38, p =.02). No differences were observed for persistent phrenic nerve palsy, nor for groin complications. Conclusion: CBA was significantly safer and required less radiation if ICE was used, although the procedures were more complex. The risk of groin complications was not increased with ICE usage. Non‐ICE usage was the only modifiable independent predictor of major complications. [ABSTRACT FROM AUTHOR]
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- 2023
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31. A rare case of right heart failure with the necessity for veno‐arterial extracorporeal membrane oxygenation following pulmonary vein stenosis after radiofrequency ablation for atrial fibrillation
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Kopp, Sabrina, primary, Tilch, Marie‐Kristin, additional, Sagoschen, Ingo, additional, Kaes, Joachim, additional, Kuniss, Malte, additional, Neumann, Thomas, additional, Yang, Yang, additional, Schnitzler, Katharina, additional, Schmidt, Kai‐Helge, additional, Rostock, Thomas, additional, Münzel, Thomas, additional, Konstantinides, Stavros, additional, Wild, Johannes, additional, and Hobohm, Lukas, additional
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- 2023
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32. Impact of cryoballoon application abortion due to phrenic nerve injury on reconnection rates: a YETI subgroup analysis
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Heeger, Christian-H, primary, Popescu, Sorin Ștefan, additional, Sohns, Christian, additional, Pott, Alexander, additional, Metzner, Andreas, additional, Inaba, Osamu, additional, Straube, Florian, additional, Kuniss, Malte, additional, Aryana, Arash, additional, Miyazaki, Shinsuke, additional, Cay, Serkan, additional, Ehrlich, Joachim R, additional, El-Battrawy, Ibrahim, additional, Martinek, Martin, additional, Saguner, Ardan M, additional, Tscholl, Verena, additional, Yalin, Kivanc, additional, Lyan, Evgeny, additional, Su, Wilber, additional, Papiashvili, Giorgi, additional, Botros, Maichel Sobhy Naguib, additional, Gasperetti, Alessio, additional, Proietti, Riccardo, additional, Wissner, Erik, additional, Scherr, Daniel, additional, Kamioka, Masashi, additional, Makimoto, Hisaki, additional, Urushida, Tsuyoshi, additional, Aksu, Tolga, additional, Chun, Julian K R, additional, Aytemir, Kudret, additional, Jędrzejczyk-Patej, Ewa, additional, Kuck, Karl-Heinz, additional, Dahme, Tillman, additional, Steven, Daniel, additional, Sommer, Philipp, additional, and Tilz, Roland Richard, additional
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- 2022
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33. Guideline Directed Medical Therapy at Discharge and Further Uptitration Leading to Reduction in Indication for Prophylactic ICD Implantation during Protected Waiting Period
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Waezsada, Elias, primary, Hutter, Julie, additional, Kahle, Patrick, additional, Yogarajah, Joerg, additional, Sperzel, Johannes, additional, Kuniss, Malte, additional, Neumann, Thomas, additional, Esser, Horst, additional, Hamm, Christian, additional, and Hain, Andreas, additional
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- 2022
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34. Ice or fire? Comparison of second‐generation cryoballoon ablation and radiofrequency ablation in patients with symptomatic persistent atrial fibrillation and an enlarged left atrium
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Akkaya, Ersan, Berkowitsch, Alexander, Zaltsberg, Sergej, Greiss, Harald, Hamm, Christian W., Sperzel, Johannes, Neumann, Thomas, and Kuniss, Malte
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- 2018
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35. Second‐generation cryoballoon ablation for treatment of persistent atrial fibrillation: Three‐year outcome and predictors of recurrence after a single procedure
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Akkaya, Ersan, Berkowitsch, Alexander, Zaltsberg, Sergej, Greiss, Harald, Hamm, Christian W., Sperzel, Johannes, Neumann, Thomas, and Kuniss, Malte
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- 2018
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36. Typisches Vorhofflattern: Diagnostik und Therapie
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Thomas, Dierk, Eckardt, Lars, Estner, Heidi L., Kuniss, Malte, Meyer, Christian, Neuberger, Hans-Ruprecht, Sommer, Philipp, Steven, Daniel, Voss, Frederik, and Bonnemeier, Hendrik
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- 2016
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37. AV-Knoten-Reentrytachykardie: Diagnostik und Therapie
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von Bary, Christian, Eckardt, Lars, Steven, Daniel, Neuberger, Hans-Ruprecht, Tilz, Roland Richard, Bonnemeier, Hendrik, Thomas, Dierck, Deneke, Thomas, Estner, Heidi L., Kuniss, Malte, Luik, Armin, Sommer, Philipp, Voss, Frederik, Meyer, Christian, Shin, D.I., and Kriatselis, Charalampos
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- 2015
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38. New evidence: Cryoballoon ablation vs. antiarrhythmic drugs for first-line therapy of atrial fibrillation
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Andrade, Jason G, primary, Chierchia, Gian-Battista, additional, Kuniss, Malte, additional, and Wazni, Oussama M, additional
- Published
- 2022
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39. Correction to: Comparative effectiveness and safety of non-vitamin K antagonists for atrial fibrillation in clinical practice: GLORIA-AF Registry (Clinical Research in Cardiology, (2022), 111, 5, (560-573), 10.1007/s00392-022-01996-2)
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Lip, Gregory Y. H., Kotalczyk, Agnieszka, Teutsch, Christine, Diener, Hans-Christoph, Dubner, Sergio J., Halperin, Jonathan L., Ma, Chang-Sheng, Rothman, Kenneth J., Marler, Sabrina, Gurusamy, Venkatesh Kumar, Huisman, Menno V., Abban, Dzifa Wosornu, Aziz, Emad, Kalan, Marica Bracic, Abdul, Nasser, Backes, Luciano Marcelo, Bradman, Drew, Abud, Atilio Marcelo, Badings, E., Brautigam, Donald, Adams, Fran, Bagni, Ermentina, Breton, Nicolas, Addala, Srinivas, Baker, Seth H., Brouwers, P. J. A. M., Adragão, Pedro, Bala, Richard, Browne, Kevin, Ageno, Walter, Baldi, Antonio, Cortada, Jordi Bruguera, Aggarwal, Rajesh, Bando, Shigenobu, Bruni, A., Agosti, Sergio, Banerjee, Subhash, Brunschwig, Claude, Agostoni, Piergiuseppe, Bank, Alan, Buathier, Hervé, Aguilar, Francisco, Esquivias, Gonzalo Barón, Buhl, Aurélie, Linares, Julio Aguilar, Barr, Craig, Bullinga, John, Aguinaga, Luis, Bartlett, Maria, Cabrera, Jose Walter, Ahmed, Jameel, Basic Kes, Vanja, Caccavo, Alberto, Aiello, Allessandro, Baula, Giovanni, Cai, Shanglang, Ainsworth, Paul, Behrens, Steffen, Caine, Sarah, Aiub, Jorge Roberto, Bell, Alan, Calò, Leonardo, Al-Dallow, Raed, Benedetti, Raffaella, Calvi, Valeria, Alderson, Lisa, Mazuecos, Juan Benezet, Sánchez, Mauricio Camarillo, Velasco, Jorge Antonio Aldrete, Benhalima, Bouziane, Candeias, Rui, Alexopoulos, Dimitrios, Bergler-Klein, Jutta, Capuano, Vincenzo, Manterola, Fernando Alfonso, Berneau, Jean-Baptiste, Capucci, Alessandro, Aliyar, Pareed, Bernstein, Richard A., Caputo, Ronald, Alonso, David, Berrospi, Percy, Rizo, Tatiana C. rdenas, da Costa, Fernando Augusto Alves, Berti, Sergio, Cardona, Francisco, Amado, José, Berz, Andrea, da Costa Darrieux, Francisco Carlos, Amara, Walid, Best, Elizabeth, Vera, Yan Carlos Duarte, Amelot, Mathieu, Bettencourt, Paulo, Carolei, Antonio, Amjadi, Nima, Betzu, Robert, Carreño, Susana, Ammirati, Fabrizio, Bhagwat, Ravi, Carvalho, Paula, Andrade, Marianna, Bhatta, Luna, Cary, Susanna, Andrawis, Nabil, Biscione, Francesco, Casu, Gavino, Annoni, Giorgio, Bisignani, Giovanni, Cavallini, Claudio, Ansalone, Gerardo, Black, Toby, Cayla, Guillaume, Ariani, M. Kevin, Bloch, Michael J., Celentano, Aldo, Arias, Juan Carlos, Bloom, Stephen, Cha, Tae-Joon, Armero, S. bastien, Blumberg, Edwin, Cha, Kwang Soo, Arora, Chander, Bo, Mario, Chae, Jei Keon, Aslam, Muhammad Shakil, Bøhmer, Ellen, Chalamidas, Kathrine, Asselman, M., Bollmann, Andreas, Challappa, Krishnan, Audouin, Philippe, Bongiorni, Maria Grazia, Chand, Sunil Prakash, Augenbraun, Charles, Boriani, Giuseppe, Chandrashekar, Harinath, Aydin, S., Boswijk, D. J., Chartier, Ludovic, Bott, Jochen, Chatterjee, Kausik, Ayryanova, Ivaneta, Bottacchi, Edo, Ayala, Carlos Antero Chavez, Cheema, Aamir, Davis, Gershan, Evonich, Rudolph, Cheema, Amjad, Davy, Jean-Marc, Evseeva, Oksana, Chen, Lin, Dayer, Mark, Ezhov, Andrey, Chen, Shih-Ann, de Biasio, Marzia, Fahmy, Raed, Chen, Jyh Hong, de Bonis, Silvana, Fang, Quan, Chiang, Fu-Tien, de Caterina, Raffaele, Farsad, Ramin, Chiarella, Francesco, de Franceschi, Teresiano, Fauchier, Laurent, Chih-Chan, Lin, de Groot, J. R., Favale, Stefano, Cho, Yong Keun, de Horta, José, Fayard, Maxime, Choi, Jong-Il, de la Briolle, Axel, Fedele, Jose Luis, Choi, Dong Ju, de la Pena Topete, Gilberto, Fedele, Francesco, Chouinard, Guy, de Paola, Angelo Amato Vicenzo, Fedorishina, Olga, Chow, Danny Hoi-Fan, de Souza, Weimar, Fera, Steven R., Chrysos, Dimitrios, de Veer, A., Ferreira, Luis Gustavo Gomes, Chumakova, Galina, de Wolf, Luc, Ferreira, Jorge, Valenzuela, Eduardo Julián José Roberto Chuquiure, Decoulx, Eric, Ferri, Claudio, Nica, Nicoleta Cindea, Deepak, Sasalu, Ferrier, Anna, Cislowski, David J., Defaye, Pascal, Ferro, Hugo, Clay, Anthony, Munoz, Freddy Del-Carpio, Finsen, Alexandra, Clifford, Piers, Brkljacic, Diana Delic, First, Brian, Cohen, Andrew, Deumite, N. Joseph, Fischer, Stuart, Cohen, Michael, di Legge, Silvia, Fonseca, Catarina, Cohen, Serge, Diemberger, Igor, Almeida, Luísa Fonseca, Colivicchi, Furio, Dietz, Denise, Forman, Steven, Collins, Ronan, Dionísio, Pedro, Frandsen, Brad, Colonna, Paolo, Dong, Qiang, French, William, Compton, Steve, dos Santos, Fabio Rossi, Friedman, Keith, Connolly, Derek, Dotcheva, Elena, Friese, Athena, Conti, Alberto, Doukky, Rami, Fruntelata, Ana Gabriela, Buenostro, Gabriel Contreras, D’Souza, Anthony, Fujii, Shigeru, Coodley, Gregg, Dubrey, Simon, Fumagalli, Stefano, Cooper, Martin, Ducrocq, Xavier, Fundamenski, Marta, Coronel, Julian, Dupljakov, Dmitry, Furukawa, Yutaka, Corso, Giovanni, Duque, Mauricio, Gabelmann, Matthias, Sales, Juan Cosín, Dutta, Dipankar, Gabra, Nashwa, Cottin, Yves, Duvilla, Nathalie, Gadsbøll, Niels, Covalesky, John, Duygun, A., Galinier, Michel, Cracan, Aurel, Dziewas, Rainer, Gammelgaard, Anders, Crea, Filippo, Eaton, Charles B., Ganeshkumar, Priya, Crean, Peter, Eaves, William, Gans, Christopher, Crenshaw, James, Ebels-Tuinbeek, L. A., Quintana, Antonio Garcia, Cullen, Tina, Ehrlich, Clifford, Gartenlaub, Olivier, Darius, Harald, Eichinger-Hasenauer, Sabine, Gaspardone, Achille, Dary, Patrick, Eisenberg, Steven J., Genz, Conrad, Dascotte, Olivier, Jabali, Adnan El, Georger, Frédéric, Dauber, Ira, Shahawy, Mahfouz El, Georges, Jean-Louis, Davalos, Vicente, Hernandes, Mauro Esteves, Georgeson, Steven, Davies, Ruth, Izal, Ana Etxeberria, Giedrimas, Evaldas, Gierba, Mariusz, Haruna, Tetsuya, Jarmukli, Nabil, Ortega, Ignacio Gil, Hayek, Emil, Jeanfreau, Robert J., Gillespie, Eve, Healey, Jeff, Jenkins, Ronald D., Giniger, Alberto, Hearne, Steven, Sánchez, Carlos Jerjes, Giudici, Michael C., Heffernan, Michael, Jimenez, Javier, Gkotsis, Alexandros, Heggelund, Geir, Jobe, Robert, Glotzer, Taya V., Heijmeriks, J. A., Joen-Jakobsen, Tomas, Gmehling, Joachim, Hemels, Maarten, Jones, Nicholas, Gniot, Jacek, Hendriks, I., Jorge, Jose Carlos Moura, Goethals, Peter, Henein, Sam, Jouve, Bernard, Goldbarg, Seth, Her, Sung-Ho, Jung, Byung Chun, Goldberg, Ronald, Hermany, Paul, Jung, Kyung Tae, Goldmann, Britta, del Río, Jorge Eduardo Hernández, Jung, Werner, Golitsyn, Sergey, Higashino, Yorihiko, Kachkovskiy, Mikhail, Gómez, Silvia, Hill, Michael, Kafkala, Krystallenia, Mesa, Juan Gomez, Hisadome, Tetsuo, Kalinina, Larisa, Gonzalez, Vicente Bertomeu, Hishida, Eiji, Kallmünzer, Bernd, Hermosillo, Jesus Antonio Gonzalez, Hoffer, Etienne, Kamali, Farzan, López, V. ctor Manuel González, Hoghton, Matthew, Kamo, Takehiro, Gorka, Hervé, Hong, Kui, Kampus, Priit, Gornick, Charles, Hong, Suk keun, Kashou, Hisham, Gorog, Diana, Horbach, Stevie, Kastrup, Andreas, Gottipaty, Venkat, Horiuchi, Masataka, Katsivas, Apostolos, Goube, Pascal, Hou, Yinglong, Kaufman, Elizabeth, Goudevenos, Ioannis, Hsing, Jeff, Kawai, Kazuya, Graham, Brett, Huang, Chi-Hung, Kawajiri, Kenji, Greer, G. Stephen, Huckins, David, Kazmierski, John F., Gremmler, Uwe, Hughes, Kathy, Keeling, P., Grena, Paul G., Huizinga, A., Saraiva, José Francisco Kerr, Grond, Martin, Hulsman, E. L., Ketova, Galina, Gronda, Edoardo, Hung, Kuo-Chun, Khaira, Ajit Singh, Grönefeld, Gerian, Hwang, Gyo-Seung, Khripun, Aleksey, Gu, Xiang, Ikpoh, Margaret, Kim, Doo-Il, Torres, Ivett Guadalupe Torres, Imberti, Davide, Kim, Young Hoon, Guardigli, Gabriele, Ince, H. seyin, Kim, Nam Ho, Guevara, Carolina, Indolfi, Ciro, Kim, Dae Kyeong, Guignier, Alexandre, Inoue, Shujiro, Kim, Jeong Su, Gulizia, Michele, Irles, Didier, Kim, June Soo, Gumbley, Michael, Iseki, Harukazu, Kim, Ki Seok, Günther, Albrecht, Israel, C. Noah, Kim, Jin bae, Ha, Andrew, Iteld, Bruce, Kinova, Elena, Hahalis, Georgios, Iyer, Venkat, Klein, Alexander, Hakas, Joseph, Jackson-Voyzey, Ewart, Kmetzo, James J., Hall, Christian, Jaffrani, Naseem, Kneller, G. Larsen, Han, Bing, Jäger, Frank, Knezevic, Aleksandar, Han, Seongwook, James, Martin, Koh, Su Mei Angela, Hargrove, Joe, Jang, Sung-Won, Koide, Shunichi, Hargroves, David, Jaramillo, Nicolas, Kollias, Anastasios, Kooistra, J. A., Li, Weihua, McClure, John, Koons, Jay, Li, Xiaoming, McCormack, Terry, Koschutnik, Martin, Lichy, Christhoh, McGarity, William, Kostis, William J., Lieber, Ira, McIntyre, Hugh, Kovacic, Dragan, Rodriguez, Ramon Horacio Limon, McLaurin, Brent, Kowalczyk, Jacek, Lin, Hailong, Alvaro, Feliz, Palomino, Medina, Koziolova, Natalya, Melandri, Francesco, Kraft, Peter, Liu, Feng, Meno, Hiroshi, Kragten, Johannes A., Liu, Hengliang, Menzies, Dhananjai, Krantz, Mori, Esperon, Guillermo Llamas, Mercader, Marco, Krause, Lars, Navarro, Nassip Llerena, Meyer, Christian, Krenning, B. J., Lo, Eric, Meyer, Beat J., Krikke, F., Lokshyn, Sergiy, Miarka, Jacek, Kromhout, Z., López, Amador, Mibach, Frank, Krysiak, Waldemar, López-Sendón, José Luís, Michalski, Dominik, Kumar, Priya, Filho, Adalberto Menezes Lorga, Michel, Patrik, Kümler, Thomas, Lorraine, Richard S., Chreih, Rami Mihail, Kuniss, Malte, Luengas, Carlos Alberto, Luengas, Alberto, Mikdadi, Ghiath, Kuo, Jen-Yuan, Luke, Robert, Mikus, Milan, Küppers, Achim, Luo, Ming, Milicic, Davor, Kurrelmeyer, Karla, Lupovitch, Steven, Militaru, Constantin, Kwak, Choong Hwan, Lyrer, Philippe, Minaie, Sedi, Laboulle, B. nédicte, Ma, Changsheng, Minescu, Bogdan, Labovitz, Arthur, Ma, Genshan, Mintale, Iveta, ter Lai, Wen, Madariaga, Irene, Mirault, Tristan, Lam, Andy, Maeno, Koji, Mirro, Michael J., Lam, Yat Yin, Magnin, Dominique, Mistry, Dinesh, Lanas Zanetti, Fernando, Maid, Gustavo, Miu, Nicoleta Violeta, Landau, Charles, Mainigi, Sumeet K., Miyamoto, Naomasa, Landini, Giancarlo, Makaritsis, Konstantinos, Moccetti, Tiziano, Lanna Figueiredo, Estêvão, Malhotra, Rohit, Mohammed, Akber, Larsen, Torben, Manning, Rickey, Nor, Azlisham Mohd, Lavandier, Karine, Manolis, Athanasios, Mollerus, Michael, LeBlanc, Jessica, Hurtado, Helard Andres Manrique, Molon, Giulio, Lee, Moon Hyoung, Mantas, Ioannis, Mondillo, Sergio, Lee, Chang-Hoon, Jattin, Fernando Manzur, Moniz, Patrícia, Lehman, John, Maqueda, Vicky, Mont, Lluis, Leitão, Ana, Marchionni, Niccolo, Montagud, Vicente, Lellouche, Nicolas, Ortuno, Francisco Marin, Montaña, Oscar, Lelonek, Malgorzata, Santana, Antonio Martín, Monti, Cristina, Lenarczyk, Radoslaw, Martinez, Jorge, Moretti, Luciano, Lenderink, T., Maskova, Petra, Mori, Kiyoo, González, Salvador León, Hernandez, Norberto Matadamas, Moriarty, Andrew, Leong-Sit, Peter, Matsuda, Katsuhiro, Morka, Jacek, Leschke, Matthias, Maurer, Tillmann, Moschini, Luigi, Ley, Nicolas, Mauro, Ciro, Moschos, Nikitas, Li, Zhanquan, May, Erik, Mügge, Andreas, Li, Xiaodong, Mayer, Nolan, Mulhearn, Thomas J., Muresan, Carmen, Jose, Eena Padayattil, Précoma, Dalton Bertolim, Muriago, Michela, Padilla, Francisco Gerardo Padilla, Prelle, Alessandro, Musial, Wlodzimierz, Rios, Victoria Padilla, Prodafikas, John, Musser, Carl W., Pajes, Giuseppe, Protasov, Konstantin, Musumeci, Francesco, Pandey, A. Shekhar, Pye, Maurice, Nageh, Thuraia, Paparella, Gaetano, Qiu, Zhaohui, Nakagawa, Hidemitsu, Paris, F., Quedillac, Jean-Michel, Nakamura, Yuichiro, Park, Hyung Wook, Raev, Dimitar, Nakayama, Toru, Park, Jong Sung, Grado, Carlos Antonio Raffo, Nam, Gi-Byoung, Parthenakis, Fragkiskos, Rahimi, Sidiqullah, Nanna, Michele, Passamonti, Enrico, Raisaro, Arturo, Natarajan, Indira, Patel, Rajesh J., Rama, Bhola, Nayak, Hemal M., Patel, Jaydutt, Ramos, Ricardo, Naydenov, Stefan, Patel, Mehool, Ranieri, Maria, Nazlić, Jurica, Patrick, Janice, Raposo, Nuno, Nechita, Alexandru Cristian, Jimenez, Ricardo Pavón, Rashba, Eric, Nechvatal, Libor, Paz, Analía, Rauch-Kroehnert, Ursula, Negron, Sandra Adela, Pengo, Vittorio, Reddy, Ramakota, Neiman, James, Pentz, William, Renda, Giulia, Neuenschwander, Fernando Carvalho, Pérez, Beatriz, Reza, Shabbir, Neves, David, Ríos, Alma Minerva P. rez, Ria, Luigi, Neykova, Anna, Pérez-Cabezas, Alejandro, Richter, Dimitrios, Miguel, Ricardo Nicolás, Perlman, Richard, Rickli, Hans, Nijmeh, George, Persic, Viktor, Rieker, Werner, Nizov, Alexey, Perticone, Francesco, Vera, Tomas Ripolil, Campos, Rodrigo Noronha, Peters, Terri K., Ritt, Luiz Eduardo, Nossan, Janko, Petkar, Sanjiv, Roberts, Douglas, Novikova, Tatiana, Pezo, Luis Felipe, Briones, Ignacio Rodriguez, Nowalany-Kozielska, Ewa, Pflücke, Christian, Escudero, Aldo Edwin Rodriguez, Nsah, Emmanuel, Pham, David N., Pascual, Carlos Rodríguez, Fragoso, Juan Carlos Nunez, Phillips, Roland T., Roman, Mark, Nurgalieva, Svetlana, Phlaum, Stephen, Romeo, Francesco, Nuyens, Dieter, Pieters, Denis, Ronner, E., Nyvad, Ole, Pineau, Julien, Roux, Jean-Francois, de Los Rios Ibarra, Manuel Odin, Pinter, Arnold, Rozkova, Nadezda, O’Donnell, Philip, Pinto, Fausto, Rubacek, Miroslav, O’Donnell, Martin, Pisters, R., Rubalcava, Frank, Oh, Seil, Pivac, Nediljko, Russo, Andrea M., Oh, Yong Seog, Pocanic, Darko, Rutgers, Matthieu Pierre, Oh, Dongjin, Podoleanu, Cristian, Rybak, Karin, O‘Hara, Gilles, Politano, Alessandro, Said, Samir, Oikonomou, Kostas, Poljakovic, Zdravka, Sakamoto, Tamotsu, Olivares, Claudia, Pollock, Stewart, Salacata, Abraham, Oliver, Richard, Garcéa, Jose Polo, Salem, Adrien, Ruiz, Rafael Olvera, Poppert, Holger, Bodes, Rafael Salguero, Olympios, Christoforos, Porcu, Maurizio, Saltzman, Marco A., Omaszuk-Kazberuk, Anna, Reino, Antonio Pose, Salvioni, Alessandro, Asensi, Joaquín Osca, Prasad, Neeraj, Vallejo, Gregorio Sanchez, Fernández, Marcelo Sanmartín, Sokal, Adam, Tu, Tian Ming, Saporito, Wladmir Faustino, Yan, Yannie Soo Oi, Tuininga, Ype, Sarikonda, Kesari, Sotolongo, Rodolfo, Turakhia, Minang, Sasaoka, Taishi, de Souza, Olga Ferreira, Turk, Samir, Sati, Hamdi, Sparby, Jon Arne, Turner, Wayne, Savelieva, Irina, Spinar, Jindrich, Tveit, Arnljot, Scala, Pierre-Jean, Sprigings, David, Tytus, Richard, Schellinger, Peter, Spyropoulos, Alex C., Valadão, C., Scherr, Carlos, Stakos, Dimitrios, van Bergen, P. F. M. M., Schmitz, Lisa, Steinwender, Clemens, van de Borne, Philippe, Schmitz, Karl-Heinz, Stergiou, Georgios, van den Berg, B. J., Schmitz, Bettina, Stiell, Ian, van der Zwaan, C., Schnabel, Teresa, Stoddard, Marcus, van Eck, M., Schnupp, Steffen, Stoikov, Anastas, Vanacker, Peter, Schoeniger, Peter, Streb, Witold, Vasilev, Dimo, Schön, Norbert, Styliadis, Ioannis, Vasilikos, Vasileios, Schwimmbeck, Peter, Su, Guohai, Vasilyev, Maxim, Seamark, Clare, Su, Xi, Veerareddy, Srikar, Searles, Greg, Sudnik, Wanda, Miño, Mario Vega, Seidl, Karl-Heinz, Sukles, Kai, Venkataraman, Asok, Seidman, Barry, Sun, Xiaofei, Verdecchia, Paolo, Sek, Jaroslaw, Swart, H., Versaci, Francesco, Sekaran, Lakshmanan, Szavits-Nossan, Janko, Vester, Ernst G. nter, Serrati, Carlo, Taggeselle, Jens, Vial, Hubert, Shah, Neerav, Takagi, Yuichiro, Victory, Jason, Shah, Vinay, Takhar, Amrit Pal Singh, Villamil, Alejandro, Shah, Anil, Tamm, Angelika, Vincent, Marc, Shah, Shujahat, Tanaka, Katsumi, Vlastaris, Anthony, Sharma, Vijay Kumar, Tanawuttiwat, Tanyanan, Dahl, J. rgen vom, Shaw, Louise, Tang, Sherman, Vora, Kishor, Sheikh, Khalid H., Tang, Aylmer, Vranian, Robert B., Shimizu, Naruhito, Tarsi, Giovanni, Wakefield, Paul, Shimomura, Hideki, Tassinari, Tiziana, Wang, Ningfu, Shin, Dong-Gu, Tayal, Ashis, Wang, Mingsheng, Shin, Eun-Seok, Tayebjee, Muzahir, Wang, Xinhua, Shite, Junya, Berg, J. M. ten, Wang, Feng, Sibilio, Gerolamo, Tesloianu, Dan, Wang, Tian, Silver, Frank, The, Salem H. K., Warner, Alberta L., Sime, Iveta, Thomas, Dierk, Watanabe, Kouki, Simmers, Tim A., Timsit, Serge, Wei, Jeanne, Singh, Narendra, Tobaru, Tetsuya, Weimar, Christian, Siostrzonek, Peter, Tomasik, Andrzej R., Weiner, Stanislav, Smadja, Didier, Torosoff, Mikhail, Weinrich, Renate, Smith, David W., Touze, Emmanuel, Wen, Ming-Shien, Snitman, Marcelo, Trendafilova, Elina, Wiemer, Marcus, Filho, Dario Sobral, Tsai, W. Kevin, Wiggers, Preben, Soda, Hassan, Tse, Hung Fat, Wilke, Andreas, Sofley, Carl, Tsutsui, Hiroshi, Williams, David, Williams, Marcus L., Yan, Ping Yen Bryan, Zhang, Ping, Witzenbichler, Bernhard, Yang, Tianlun, Zhang, Jun, Wong, Brian, Yao, Jing, Zhao, Shui Ping, Wong, Ka Sing Lawrence, Yeh, Kuo-Ho, Zhao, Yujie, Wozakowska-Kaplon, Beata, Yin, Wei Hsian, Zhao, Zhichen, Wu, Shulin, Yotov, Yoto, Zheng, Yang, Wu, Richard C., Zahn, Ralf, Zhou, Jing, Wunderlich, Silke, Zarich, Stuart, Zimmermann, Sergio, Wyatt, Nell, Zenin, Sergei, Zini, Andrea, Wylie, John, Zeuthen, Elisabeth Louise, Zizzo, Steven, Xu, Yong, Zhang, Huanyi, Zong, Wenxia, Xu, Xiangdong, Zhang, Donghui, Zukerman, L. Steven, Yamanoue, Hiroki, Zhang, Xingwei, Yamashita, Takeshi, Cardiology, and ACS - Heart failure & arrhythmias
- Abstract
In this article, the name of the GLORIA-AF investigator Anastasios Kollias was given incorrectly as Athanasios Kollias in the Acknowledgements. The original article has been corrected.
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- 2022
40. Phrenic Nerve Injury During Cryoballoon-Based Pulmonary Vein Isolation: Results of the Worldwide YETI Registry
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Heeger, Christian-H, Sohns, Christian, Pott, Alexander, Metzner, Andreas, Inaba, Osamu, Straube, Florian, Kuniss, Malte, Aryana, Arash, Miyazaki, Shinsuke, Cay, Serkan, Ehrlich, Joachim R., El-Battrawy, Ibrahim, Martinek, Martin, Saguner, Ardan M., Tscholl, Verena, Yalin, Kivanc, Lyan, Evgeny, Su, Wilber, Papiashvili, Giorgi, Botros, Maichel Sobhy Naguib, Gasperetti, Alessio, Proietti, Riccardo, Wissner, Erik, Scherr, Daniel, Kamioka, Masashi, Makimoto, Hisaki, Urushida, Tsuyoshi, Aksu, Tolga, Chun, Julian K. R., Aytemir, Kudret, Jedrzejczyk-Patej, Ewa, Kuck, Karl-Heinz, Dahme, Tillman, Steven, Daniel, Sommer, Philipp, Tilz, Roland Richard, Heeger, Christian-H, Sohns, Christian, Pott, Alexander, Metzner, Andreas, Inaba, Osamu, Straube, Florian, Kuniss, Malte, Aryana, Arash, Miyazaki, Shinsuke, Cay, Serkan, Ehrlich, Joachim R., El-Battrawy, Ibrahim, Martinek, Martin, Saguner, Ardan M., Tscholl, Verena, Yalin, Kivanc, Lyan, Evgeny, Su, Wilber, Papiashvili, Giorgi, Botros, Maichel Sobhy Naguib, Gasperetti, Alessio, Proietti, Riccardo, Wissner, Erik, Scherr, Daniel, Kamioka, Masashi, Makimoto, Hisaki, Urushida, Tsuyoshi, Aksu, Tolga, Chun, Julian K. R., Aytemir, Kudret, Jedrzejczyk-Patej, Ewa, Kuck, Karl-Heinz, Dahme, Tillman, Steven, Daniel, Sommer, Philipp, and Tilz, Roland Richard
- Abstract
Background: Cryoballoon-based pulmonary vein isolation (PVI) has emerged as an effective treatment for atrial fibrillation. The most frequent complication during cryoballoon-based PVI is phrenic nerve injury (PNI). However, data on PNI are scarce. Methods: The YETI registry is a retrospective, multicenter, and multinational registry evaluating the incidence, characteristics, prognostic factors for PNI recovery and follow-up data of patients with PNI during cryoballoon-based PVI. Experienced electrophysiological centers were invited to participate. All patients with PNI during CB2 or third (CB3) and fourth-generation cryoballoon (CB4)-based PVI were eligible. Results: A total of 17 356 patients underwent cryoballoon-based PVI in 33 centers from 10 countries. A total of 731 (4.2%) patients experienced PNI. The mean time to PNI was 127.7 +/- 50.4 seconds, and the mean temperature at the time of PNI was -49 +/- 8 degrees C. At the end of the procedure, PNI recovered in 394/731 patients (53.9%). Recovery of PNI at 12 months of follow-up was found in 97.0% of patients (682/703, with 28 patients lost to follow-up). A total of 16/703 (2.3%) reported symptomatic PNI. Only 0.06% of the overall population showed symptomatic and permanent PNI. Prognostic factors improving PNI recovery are immediate stop at PNI by double-stop technique and utilization of a bonus-freeze protocol. Age, cryoballoon temperature at PNI, and compound motor action potential amplitude loss >30% were identified as factors decreasing PNI recovery. Based on these parameters, a score was calculated. The YETI score has a numerical value that will directly represent the probability of a specific patient of recovering from PNI within 12 months. Conclusions: The incidence of PNI during cryoballoon-based PVI was 4.2%. Overall 97% of PNI recovered within 12 months. Symptomatic and permanent PNI is exceedingly rare in patients after cryoballoon-based PVI. The YETI score estimates the prognosis after iatrogenic cry
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- 2022
41. Phrenic Nerve Injury During Cryoballoon-Based Pulmonary Vein Isolation: Results of the Worldwide YETI Registry
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Heeger, Christian-H; https://orcid.org/0000-0002-9014-8097, Sohns, Christian; https://orcid.org/0000-0003-0490-5862, Pott, Alexander, Metzner, Andreas, Inaba, Osamu; https://orcid.org/0000-0003-2179-3786, Straube, Florian; https://orcid.org/0000-0002-4491-5224, Kuniss, Malte; https://orcid.org/0000-0002-1593-9657, Aryana, Arash; https://orcid.org/0000-0003-0932-8400, Miyazaki, Shinsuke; https://orcid.org/0000-0002-0230-0934, Cay, Serkan; https://orcid.org/0000-0002-5476-1214, Ehrlich, Joachim R; https://orcid.org/0000-0002-5803-9843, El-Battrawy, Ibrahim; https://orcid.org/0000-0002-0139-1045, Martinek, Martin; https://orcid.org/0000-0002-8895-8488, Saguner, Ardan M; https://orcid.org/0000-0003-1896-0803, Tscholl, Verena; https://orcid.org/0000-0003-2748-2540, Yalin, Kivanc; https://orcid.org/0000-0001-5602-0711, Lyan, Evgeny; https://orcid.org/0000-0001-9696-9227, Su, Wilber; https://orcid.org/0000-0002-0639-6822, Papiashvili, Giorgi; https://orcid.org/0000-0002-6183-6683, Botros, Maichel Sobhy Naguib; https://orcid.org/0000-0003-1521-1495, Gasperetti, Alessio; https://orcid.org/0000-0003-3432-070X, Proietti, Riccardo, Wissner, Erik, Scherr, Daniel, Kamioka, Masashi; https://orcid.org/0000-0001-6588-0764, Makimoto, Hisaki, Urushida, Tsuyoshi, Aksu, Tolga; https://orcid.org/0000-0001-8061-9660, Chun, Julian K R; https://orcid.org/0000-0002-2355-6015, Aytemir, Kudret; https://orcid.org/0000-0001-9279-8424, et al, Heeger, Christian-H; https://orcid.org/0000-0002-9014-8097, Sohns, Christian; https://orcid.org/0000-0003-0490-5862, Pott, Alexander, Metzner, Andreas, Inaba, Osamu; https://orcid.org/0000-0003-2179-3786, Straube, Florian; https://orcid.org/0000-0002-4491-5224, Kuniss, Malte; https://orcid.org/0000-0002-1593-9657, Aryana, Arash; https://orcid.org/0000-0003-0932-8400, Miyazaki, Shinsuke; https://orcid.org/0000-0002-0230-0934, Cay, Serkan; https://orcid.org/0000-0002-5476-1214, Ehrlich, Joachim R; https://orcid.org/0000-0002-5803-9843, El-Battrawy, Ibrahim; https://orcid.org/0000-0002-0139-1045, Martinek, Martin; https://orcid.org/0000-0002-8895-8488, Saguner, Ardan M; https://orcid.org/0000-0003-1896-0803, Tscholl, Verena; https://orcid.org/0000-0003-2748-2540, Yalin, Kivanc; https://orcid.org/0000-0001-5602-0711, Lyan, Evgeny; https://orcid.org/0000-0001-9696-9227, Su, Wilber; https://orcid.org/0000-0002-0639-6822, Papiashvili, Giorgi; https://orcid.org/0000-0002-6183-6683, Botros, Maichel Sobhy Naguib; https://orcid.org/0000-0003-1521-1495, Gasperetti, Alessio; https://orcid.org/0000-0003-3432-070X, Proietti, Riccardo, Wissner, Erik, Scherr, Daniel, Kamioka, Masashi; https://orcid.org/0000-0001-6588-0764, Makimoto, Hisaki, Urushida, Tsuyoshi, Aksu, Tolga; https://orcid.org/0000-0001-8061-9660, Chun, Julian K R; https://orcid.org/0000-0002-2355-6015, Aytemir, Kudret; https://orcid.org/0000-0001-9279-8424, and et al
- Abstract
BACKGROUND Cryoballoon-based pulmonary vein isolation (PVI) has emerged as an effective treatment for atrial fibrillation. The most frequent complication during cryoballoon-based PVI is phrenic nerve injury (PNI). However, data on PNI are scarce. METHODS The YETI registry is a retrospective, multicenter, and multinational registry evaluating the incidence, characteristics, prognostic factors for PNI recovery and follow-up data of patients with PNI during cryoballoon-based PVI. Experienced electrophysiological centers were invited to participate. All patients with PNI during CB2 or third (CB3) and fourth-generation cryoballoon (CB4)-based PVI were eligible. RESULTS A total of 17 356 patients underwent cryoballoon-based PVI in 33 centers from 10 countries. A total of 731 (4.2%) patients experienced PNI. The mean time to PNI was 127.7±50.4 seconds, and the mean temperature at the time of PNI was -49±8°C. At the end of the procedure, PNI recovered in 394/731 patients (53.9%). Recovery of PNI at 12 months of follow-up was found in 97.0% of patients (682/703, with 28 patients lost to follow-up). A total of 16/703 (2.3%) reported symptomatic PNI. Only 0.06% of the overall population showed symptomatic and permanent PNI. Prognostic factors improving PNI recovery are immediate stop at PNI by double-stop technique and utilization of a bonus-freeze protocol. Age, cryoballoon temperature at PNI, and compound motor action potential amplitude loss >30% were identified as factors decreasing PNI recovery. Based on these parameters, a score was calculated. The YETI score has a numerical value that will directly represent the probability of a specific patient of recovering from PNI within 12 months. CONCLUSIONS The incidence of PNI during cryoballoon-based PVI was 4.2%. Overall 97% of PNI recovered within 12 months. Symptomatic and permanent PNI is exceedingly rare in patients after cryoballoon-based PVI. The YETI score estimates the prognosis after iatrogenic cryoballoon-derived PNI
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- 2022
42. Safety and feasibility of percutaneous skin closure using purse-string suture compared with compression bandage after pulmonary vein isolation
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Akkaya, Ersan, Berkowitsch, Alexander, Zaltsberg, Sergej, Deubner, Nikolas, Greiss, Harald, Hain, Andreas, Hamm, Christian W., Sperzel, Johannes, Neumann, Thomas, and Kuniss, Malte
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- 2017
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43. The slope of the initial temperature drop predicts acute pulmonary vein isolation using the second-generation cryoballoon
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Deubner, Nikolas, Greiss, Harald, Akkaya, Ersan, Zaltsberg, Sergey, Hain, Andreas, Berkowitsch, Alexander, Güttler, Norbert, Kuniss, Malte, and Neumann, Thomas
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- 2017
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44. High Resting Heart Rates Are Associated with Early Posthospitalization Mortality in Low Ejection Fraction Patients
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Hain, Andreas, primary, Busch, Nikolai, additional, Waezsada, Said Elias, additional, Hutter, Julie, additional, Kahle, Patrick, additional, Kuniss, Malte, additional, Neumann, Thomas, additional, Masuda, Tsyuoshi, additional, Esser, Horst O., additional, Hamm, Christian, additional, and Sperzel, Johannes, additional
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- 2022
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45. PO-651-01 THE YETI REGISTRY: RESULTS OF A WORLD-WIDE ANALYSIS OF PHRENIC NERVE INJURY DURING CRYOBALOON BASED PULMONARY VEIN ISOLATION
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Heeger, Christian H., primary, Sohns, Christian, additional, Pott, Alexander, additional, Metzner, Andreas, additional, Inaba, Osamu, additional, Straube, Florian, additional, Kuniss, Malte, additional, Aryana, Arash, additional, Miyazaki, Shinsuke, additional, CAY, SERKAN, additional, Ehrlich, Joachim R., additional, Martinek, Martin, additional, Saguner, Ardan, additional, Tscholl, Verena, additional, Yalin, Kivanc, additional, Lyan, Evgeny, additional, Su, Wilber W., additional, Papiashvili, Giorgi, additional, Sobhy naguib Botros, MAICHEL, additional, Gasperetti, Alessio, additional, Proietti, Riccardo, additional, Wissner, Erik, additional, Scherr, Daniel, additional, Kamioka, Masashi, additional, Makimoto, Hisaki, additional, Aksu, Tolga, additional, Kyoung-Ryul Chun, Julian, additional, AYTEMIR, KUDRET, additional, Kuck, Karl-Heinz, additional, Dahme, Tillman, additional, Steven, Daniel, additional, Sommer, Philipp, additional, and Tilz, Roland R., additional
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- 2022
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46. First-line catheter ablation of paroxysmal atrial fibrillation: outcome of radiofrequency vs. cryoballoon pulmonary vein isolation
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Straube, Florian, Dorwarth, Uwe, Ammar-Busch, Sonia, Peter, Timo, Noelker, Georg, Massa, Thomas, Kuniss, Malte, Ewertsen, Niels Christian, Chun, Kyoung Ryul Julian, Tebbenjohanns, Juergen, Tilz, Roland, Kuck, Karl Heinz, Ouarrak, Taoufik, Senges, Jochen, and Hoffmann, Ellen
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- 2016
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47. Cryoballoon ablation vs. antiarrhythmic drugs
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Cryo-FIRST Investigators, Kuniss, Malte, Pavlovic, Nikola, Velagic, Vedran, Hermida, Jean Sylvain, Healey, Stewart, Arena, Giuseppe, Badenco, Nicolas, Meyer, Christian, Chen, Jian, Iacopino, Saverio, Anselme, Frédéric, Packer, Douglas L, Pitschner, Heinz-Friedrich, de Asmundis, Carlo, Willems, Stephan, Di Piazza, Fabio, Becker, Daniel, Chierchia, Gian-Battista, Clinical sciences, Heartrhythmmanagement, HAL-SU, Gestionnaire, Kerckhoff-Klinik, University Hospital Sestre Milosrdnice, University Hospital Centre Zagreb, Partenaires INRAE, CHU Amiens-Picardie, Monash Health and Hudson Institute, Institut de cardiologie [CHU Pitié-Salpêtrière], CHU Pitié-Salpêtrière [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), Unité de Recherche sur les Maladies Cardiovasculaires, du Métabolisme et de la Nutrition = Research Unit on Cardiovascular and Metabolic Diseases (ICAN), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU)-Institut de Cardiométabolisme et Nutrition = Institute of Cardiometabolism and Nutrition [CHU Pitié Salpêtrière] (IHU ICAN), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-CHU Pitié-Salpêtrière [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), University Heart Center [Hamburg], Haukeland University Hospital, University of Bergen (UiB), Maria Cecilia Hospital [Cotignola], CHU Rouen, Normandie Université (NU), Mayo Clinic, Vrije Universiteit Brussel (VUB), Medtronic SNT, Medtronic, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-CHU Pitié-Salpêtrière [AP-HP], Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), Unité de Recherche sur les Maladies Cardiovasculaires, du Métabolisme et de la Nutrition = Institute of cardiometabolism and nutrition (ICAN), and Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-CHU Pitié-Salpêtrière [AP-HP]
- Subjects
[SDV.MHEP.CHI] Life Sciences [q-bio]/Human health and pathology/Surgery ,medicine.medical_treatment ,cryoballoon ,030204 cardiovascular system & hematology ,Rate ratio ,Cryosurgery ,0302 clinical medicine ,Recurrence ,Atrial Fibrillation ,Clinical endpoint ,Palpitations ,AcademicSubjects/MED00200 ,030212 general & internal medicine ,Cryosurgery* / adverse effects ,Atrial Fibrillation* / surgery ,Atrial fibrillation ,Ablation for Atrial Fibrillation ,3. Good health ,[SDV.MHEP.CSC] Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular system ,Treatment Outcome ,Antiarrhythmic drug ,Pulmonary Veins ,[SDV.SP.PHARMA] Life Sciences [q-bio]/Pharmaceutical sciences/Pharmacology ,Cardiology ,Catheter Ablation ,Atrial Fibrillation* / drug therapy ,medicine.symptom ,Cardiology and Cardiovascular Medicine ,Anti-Arrhythmia Agents ,medicine.medical_specialty ,Pulmonary Veins* / surgery ,First-line treatment ,Catheter ablation ,[SDV.MHEP.CHI]Life Sciences [q-bio]/Human health and pathology/Surgery ,03 medical and health sciences ,[SDV.MHEP.CSC]Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular system ,Clinical Research ,Catheter Ablation* / adverse effects ,Physiology (medical) ,Internal medicine ,medicine ,Atrial Fibrillation* / diagnosis ,Humans ,Atrial tachycardia ,Surrogate endpoint ,business.industry ,medicine.disease ,Anti-Arrhythmia Agents / adverse effects ,[SDV.SP.PHARMA]Life Sciences [q-bio]/Pharmaceutical sciences/Pharmacology ,business ,randomized study ,Atrial flutter - Abstract
Aims Treatment guidelines for patients with atrial fibrillation (AF) suggest that patients should be managed with an antiarrhythmic drug (AAD) before undergoing catheter ablation (CA). This study evaluated whether pulmonary vein isolation employing cryoballoon CA is superior to AAD therapy for the prevention of atrial arrhythmia (AA) recurrence in rhythm control naive patients with paroxysmal AF (PAF). Methods and results A total of 218 treatment naive patients with symptomatic PAF were randomized (1 : 1) to cryoballoon CA (Arctic Front Advance, Medtronic) or AAD (Class I or III) and followed for 12 months. The primary endpoint was ≥1 episode of recurrent AA (AF, atrial flutter, or atrial tachycardia) >30 s after a prespecified 90-day blanking period. Secondary endpoints included the rate of serious adverse events (SAEs) and recurrence of symptomatic palpitations (evaluated via patient diaries). Freedom from AA was achieved in 82.2% of subjects in the cryoballoon arm and 67.6% of subjects in the AAD arm (HR = 0.48, P = 0.01). There were no group differences in the time-to-first (HR = 0.76, P = 0.28) or overall incidence [incidence rate ratio (IRR)=0.79, P = 0.28] of SAEs. The incidence rate of symptomatic palpitations was lower in the cryoballoon (7.61 days/year) compared with the AAD arm (18.96 days/year; IRR = 0.40, P, Graphical Abstract
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- 2021
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48. The Impact of Left Atrial Surface Area and the Second Generation Cryoballoon on Clinical Outcome of Atrial Fibrillation Cryoablation
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GREISS, HARALD, BERKOWITSCH, ALEXANDER, WOJCIK, MACIEJ, ZALTSBERG, SERGEJ, PAJITNEV, DIMITRI, DEUBNER, NIKOLAS, AKKAYA, ERSAN, GÜTTLER, NORBERT, HAMM, CHRISTIAN, NEUMANN, THOMAS, and KUNISS, MALTE
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- 2015
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49. Focal Arrhythmia Ablation Determined by High-Resolution Noninvasive Maps: Multicenter Feasibility Study
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HOCINI, MÉLÈZE, SHAH, ASHOK J., NEUMANN, THOMAS, KUNISS, MALTE, ERKAPIC, DAMIR, CHAUMEIL, ARNAUD, COPLEY, SHAHNAZ-JAMIL, LIM, PHANG BOON, KANAGARATNAM, PRAPA, DENIS, ARNAUD, DERVAL, NICOLAS, DUBOIS, RÉMI, COCHET, HUBERT, JAIS, PIERRE, and HAISSAGUERRE, MICHEL
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- 2015
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50. Clinical impact of a novel three-dimensional electrocardiographic imaging for non-invasive mapping of ventricular arrhythmias—a prospective randomized trial
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Erkapic, Damir, Greiss, Harald, Pajitnev, Dmitri, Zaltsberg, Sergey, Deubner, Nicolas, Berkowitsch, Alexander, Möllman, Susanne, Sperzel, Johannes, Rolf, Andreas, Schmitt, Jörn, Hamm, Christian W., Kuniss, Malte, and Neumann, Thomas
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- 2015
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