Search

Your search keyword '"Kong, Betty Y."' showing total 15 results
Start Over Author "Kong, Betty Y." Publication Year Range Last 10 years
15 results on '"Kong, Betty Y."'

1. Distinct Patterns of Acral Melanoma Based on Site and Relative Sun Exposure

Author

Haugh, Alexandra M., Zhang, Bin, Quan, Victor L., Garfield, Erin M., Bubley, Jeffrey A., Kudalkar, Emily, Verzi, Anna Elisa, Walton, Kara, VandenBoom, Timothy, Merkel, Emily A., Lee, Christina Y., Tan, Timothy, Isales, Maria Cristina, Kong, Betty Y., Wenzel, Alexander T., Bunick, Christopher G., Choi, Jaehyuk, Sosman, Jeffrey, and Gerami, Pedram

Published
2018
Full Text
View/download PDF

2. Distinct genomic features in a retrospective cohort of mucosal, acral, and vulvovaginal melanomas

Author

Shi, Katherine, primary, Zhang, Bin, additional, Kong, Betty Y., additional, Zhang, Yongzhan, additional, Igartua, Catherine, additional, Mohan, Lauren S., additional, Quan, Victor L., additional, Panah, Elnaz, additional, Isales, Maria Cristina, additional, Beaubier, Nike, additional, Taxter, Timothy J., additional, White, Kevin P., additional, Zou, Lihua, additional, and Gerami, Pedram, additional

Published
2023
Full Text
View/download PDF

10. The diagnostic value and histologic correlate of distinct patterns of shiny white streaks for the diagnosis of melanoma: A retrospective, case-control study

Author

Verzi, Anna Eliza, primary, Quan, Victor L., additional, Walton, Kara E., additional, Martini, Mary C., additional, Marghoob, Ashfaq A., additional, Garfield, Erin M., additional, Kong, Betty Y., additional, Isales, Maria Cristina, additional, VandenBoom, Timothy, additional, Zhang, Bin, additional, West, Dennis P., additional, and Gerami, Pedram, additional

Published
2018
Full Text
View/download PDF

14. Quantitative mapping of zinc fluxes in the mammalian egg reveals the origin of fertilization-induced zinc sparks

Author

Que, Emily L., primary, Bleher, Reiner, additional, Duncan, Francesca E., additional, Kong, Betty Y., additional, Gleber, Sophie C., additional, Vogt, Stefan, additional, Chen, Si, additional, Garwin, Seth A., additional, Bayer, Amanda R., additional, Dravid, Vinayak P., additional, Woodruff, Teresa K., additional, and O'Halloran, Thomas V., additional

Published
2014
Full Text
View/download PDF

15. Quantitative mapping of zinc fluxes in the mammalian egg reveals the origin of fertilization-induced zinc sparks.

Author

Que, Emily L., Bleher, Reiner, Duncan, Francesca E., Kong, Betty Y., Gleber, Sophie C., Vogt, Stefan, Chen, Si, Garwin, Seth A., Bayer, Amanda R., Dravid, Vinayak P., Woodruff, Teresa K., and O'Halloran, Thomas V.

Subjects
ZINC, OVUM, FERTILIZATION (Biology), SCANNING transmission electron microscopy, ENERGY dispersive X-ray spectroscopy, X-ray fluorescence, ATOMS, MAMMALS
Abstract

Fertilization of a mammalian egg initiates a series of 'zinc sparks' that are necessary to induce the egg-to-embryo transition. Despite the importance of these zinc-efflux events little is known about their origin. To understand the molecular mechanism of the zinc spark we combined four physical approaches that resolve zinc distributions in single cells: a chemical probe for dynamic live-cell fluorescence imaging and a combination of scanning transmission electron microscopy with energy-dispersive spectroscopy, X-ray fluorescence microscopy and three-dimensional elemental tomography for high-resolution elemental mapping. We show that the zinc spark arises from a system of thousands of zinc-loaded vesicles, each of which contains, on average, 106 zinc atoms. These vesicles undergo dynamic movement during oocyte maturation and exocytosis at the time of fertilization. The discovery of these vesicles and the demonstration that zinc sparks originate from them provides a quantitative framework for understanding how zinc fluxes regulate cellular processes. [ABSTRACT FROM AUTHOR]

Published
2015
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results