1. Epidemiology of fungaemia in Sweden: A nationwide retrospective observational survey.
- Author
-
Klingspor, Lena, Ullberg, Måns, Rydberg, Johan, Kondori, Nahid, Serrander, Lena, Swanberg, Jonas, Nilsson, Kenneth, Jendle Bengtén, Cecilia, Johansson, Marcus, Granlund, Margareta, Törnqvist, Eva, Nyberg, Anders, Kindlund, Karin, Ygge, Minna, Kartout‐Boukdir, Dalila, Toepfer, Michael, Hålldin, Eva, Kahlmeter, Gunnar, and Özenci, Volkan
- Subjects
- *
FUNGEMIA , *CLINICAL epidemiology , *MEDICAL care , *ANTIFUNGAL agents , *DISEASE susceptibility , *FUNGAL meningitis - Abstract
Summary: Objectives: To identify the epidemiology and antifungal susceptibilities of Candida spp. among blood culture isolates to identify the epidemiology and antifungal susceptibilities of Candida spp. among blood culture isolates in Sweden. Methods: The study was a retrospective, observational nationwide laboratory‐based surveillance for fungaemia and fungal meningitis and was conducted from September 2015 to August 2016. Results: In total, 488 Candida blood culture isolates were obtained from 471 patients (58% males). Compared to our previous study, the incidence of candidaemia has increased from 4.2/100 000 (2005‐2006) to 4.7/100 000 population/year (2015‐2016). The three most common Candida spp. isolated from blood cultures were Candida albicans (54.7%), Candida glabrata (19.7%) and species in the Candida parapsilosis complex (9.4%). Candida resistance to fluconazole was 2% in C. albicans and between 0% and 100%, in non‐albicans species other than C. glabrata and C. krusei. Resistance to voriconazole was rare, except for C. glabrata, C. krusei and C. tropicalis. Resistance to anidulafungin was 3.8% while no Candida isolate was resistant to amphotericin B. Conclusions: We report an overall increase in candidaemia but a minor decrease of C. albicans while C. glabrata and C. parapsilosis remain constant over this 10‐year period. [ABSTRACT FROM AUTHOR]
- Published
- 2018
- Full Text
- View/download PDF