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18 results on '"Kanamura, Cristina T."'

1. Differential Yellow Fever Susceptibility in New World Nonhuman Primates, Comparison with Humans, and Implications for Surveillance

Author

de Azevedo Fernandes, Natalia C.C., Guerra, Juliana M., Diaz-Delgado, Josue, Cunha, Mariana S., del C. Saad, Leila, Iglezias, Silvia D., Ressio, Rodrigo A., Cirqueira, Cinthya dos Santos, Kanamura, Cristina T., Jesus, Isis P., Maeda, Adriana Y., Vasami, Fernanda G.S., de Carvalho, Julia, de Araujo, Leonardo J.T., de Souza, Renato Pereira, Nogueira, Juliana S., Spinola, Roberta M.F., and Catao-Dias, Jose L.

Subjects
Epidemics -- Analysis -- Brazil, Yellow fever -- Risk factors -- Distribution -- Diagnosis, Primates -- Diseases, Disease susceptibility -- Analysis, Company distribution practices, Health
Abstract

Yellow fever (YF) is a zoonosis caused by YF virus (YFV; family Flaviviridae, genus Flavivirus) that has 2 established cycles in South America: urban and sylvatic. The sylvatic cycle is [...]

Published
2021
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2. RBD and Spike DNA-Based Immunization in Rabbits Elicited IgG Avidity Maturation and High Neutralizing Antibody Responses against SARS-CoV-2

Author

da Costa, Hernan H. M., primary, Orts, Diego J. B., additional, Moura, Andrew D., additional, Duarte-Neto, Amaro N., additional, Cirqueira, Cinthya S., additional, Réssio, Rodrigo A., additional, Kanamura, Cristina T., additional, Miguita, Karen, additional, Ferreira, Jerenice E., additional, Santos, Raimunda T. M., additional, Adriani, Patricia P., additional, Cunha-Junior, Jair P., additional, Astray, Renato M., additional, Catarino, Regina M., additional, Lancelotti, Marcelo, additional, and Prudencio, Carlos R., additional

Published
2023
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3. Understanding Sabiá virus infections (Brazilian mammarenavirus)

Author

Nastri, Ana Catharina, primary, Duarte-Neto, Amaro Nunes, additional, Casadio, Luciana Vilas Boas, additional, Souza, William Marciel de, additional, Claro, Ingra M., additional, Manuli, Erika R., additional, Selegatto, Gloria, additional, Salomão, Matias C., additional, Fialkovitz, Gabriel, additional, Taborda, Mariane, additional, Almeida, Bianca Leal de, additional, Magri, Marcello C., additional, Guedes, Ana Rúbia, additional, Perdigão Neto, Lauro Vieira, additional, Sataki, Fatima Mitie, additional, Guimarães, Thais, additional, Mendes-Correa, Maria Cassia, additional, Tozetto-Mendoza, Tania R., additional, Fumagalli, Marcilio Jorge, additional, Ho, Yeh-Li, additional, Maia da Silva, Camila Alves, additional, Coletti, Thaís M., additional, Goes de Jesus, Jaqueline, additional, Romano, Camila M., additional, Hill, Sarah C., additional, Pybus, Oliver, additional, Rebello Pinho, João Renato, additional, Ledesma, Felipe Lourenço, additional, Casal, Yuri R., additional, Kanamura, Cristina T., additional, Tadeu de Araújo, Leonardo José, additional, Ferreira, Camila Santos da Silva, additional, Guerra, Juliana Mariotti, additional, Figueiredo, Luiz Tadeu Moraes, additional, Dolhnikoff, Marisa, additional, Faria, Nuno R., additional, Sabino, Ester C., additional, Alves, Venâncio Avancini Ferreira, additional, and Levin, Anna S., additional

Published
2022
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5. Testicular pathology in fatal COVID‐19: A descriptive autopsy study

Author

Duarte‐Neto, Amaro N., primary, Teixeira, Thiago A., additional, Caldini, Elia G., additional, Kanamura, Cristina T., additional, Gomes‐Gouvêa, Michele S., additional, dos Santos, Angela B. G., additional, Monteiro, Renata A. A., additional, Pinho, João R. R., additional, Mauad, Thais, additional, da Silva, Luiz F. F., additional, Saldiva, Paulo H. N., additional, Dolhnikoff, Marisa, additional, Leite, Katia R. M., additional, and Hallak, Jorge, additional

Published
2021
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6. Supplemental Material, sj-pdf-1-vet-10.1177_03009858211009781 - Yellow Fever as Cause of Death of Titi Monkeys (Callicebus Spp.)

Author

De A. Fernandes, Natália C. C., Cunha, Mariana S., Guerra, Juliana M., Diaz-Delgado, Josué, Ressio, Rodrigo A., Cirqueira, Cinthya S., Kanamura, Cristina T., Fuentes-Castillo, Danny, and Catão-Dias, José Luiz

Subjects
70706 Veterinary Medicine, FOS: Clinical medicine, FOS: Veterinary sciences, 111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified
Abstract

Supplemental Material, sj-pdf-1-vet-10.1177_03009858211009781 for Yellow Fever as Cause of Death of Titi Monkeys (Callicebus Spp.) by Natália C. C. de A. Fernandes, Mariana S. Cunha, Juliana M. Guerra, Josué Diaz-Delgado, Rodrigo A. Ressio, Cinthya S. Cirqueira, Cristina T. Kanamura, Danny Fuentes-Castillo and José Luiz Catão-Dias in Veterinary Pathology

Published
2021
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7. Yellow Fever as Cause of Death of Titi Monkeys (Callicebus Spp.)

Author

Fernandes, Natália C. C. de A., primary, Cunha, Mariana S., additional, Guerra, Juliana M., additional, Diaz-Delgado, Josué, additional, Ressio, Rodrigo A., additional, Cirqueira, Cinthya S., additional, Kanamura, Cristina T., additional, Fuentes-Castillo, Danny, additional, and Catão-Dias, José Luiz, additional

Published
2021
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8. Supplemental Material, Combined_supplemental_materials-Groch_et_al - The Pathology of Cetacean Morbillivirus Infection and Comorbidities in Guiana Dolphins During an Unusual Mortality Event (Brazil, 2017–2018)

Author

Kátia R. Groch, Díaz-Delgado, Josué, Elitieri B. Santos-Neto, Ikeda, Joana M. P., Carvalho, Rafael R., Oliveira, Raissa B., Guari, Emi B., Flach, Leonardo, Sierra, Eva, Godinho, Ana I., Fernández, Antonio, Keid, Lara B., Soares, Rodrigo M., Kanamura, Cristina T., Favero, Cíntia, Ferreira-Machado, Eduardo, Sacristán, Carlos, Porter, Brian F., Bisi, Tatiana L., Azevedo, Alexandre F., Lailson-Brito, José, and Catão-Dias, José L.

Subjects
70706 Veterinary Medicine, FOS: Clinical medicine, FOS: Veterinary sciences, 111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified
Abstract

Supplemental Material, Combined_supplemental_materials-Groch_et_al for The Pathology of Cetacean Morbillivirus Infection and Comorbidities in Guiana Dolphins During an Unusual Mortality Event (Brazil, 2017–2018) by Kátia R. Groch, Josué Díaz-Delgado, Elitieri B. Santos-Neto, Joana M. P. Ikeda, Rafael R. Carvalho, Raissa B. Oliveira, Emi B. Guari, Leonardo Flach, Eva Sierra, Ana I. Godinho, Antonio Fernández, Lara B. Keid, Rodrigo M. Soares, Cristina T. Kanamura, Cíntia Favero, Eduardo Ferreira-Machado, Carlos Sacristán, Brian F. Porter, Tatiana L. Bisi, Alexandre F. Azevedo, José Lailson-Brito and José L. Catão-Dias in Veterinary Pathology

Published
2020
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9. The Pathology of Cetacean Morbillivirus Infection and Comorbidities in Guiana Dolphins During an Unusual Mortality Event (Brazil, 2017–2018)

Author

Groch, Kátia R., primary, Díaz-Delgado, Josué, additional, Santos-Neto, Elitieri B., additional, Ikeda, Joana M. P., additional, Carvalho, Rafael R., additional, Oliveira, Raissa B., additional, Guari, Emi B., additional, Flach, Leonardo, additional, Sierra, Eva, additional, Godinho, Ana I., additional, Fernández, Antonio, additional, Keid, Lara B., additional, Soares, Rodrigo M., additional, Kanamura, Cristina T., additional, Favero, Cíntia, additional, Ferreira-Machado, Eduardo, additional, Sacristán, Carlos, additional, Porter, Brian F., additional, Bisi, Tatiana L., additional, Azevedo, Alexandre F., additional, Lailson-Brito, José, additional, and Catão-Dias, José L., additional

Published
2020
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10. Testicular pathology in fatal COVID‐19: A descriptive autopsy study.

Author

Duarte‐Neto, Amaro N., Teixeira, Thiago A., Caldini, Elia G., Kanamura, Cristina T., Gomes‐Gouvêa, Michele S., dos Santos, Angela B. G., Monteiro, Renata A. A., Pinho, João R. R., Mauad, Thais, da Silva, Luiz F. F., Saldiva, Paulo H. N., Dolhnikoff, Marisa, Leite, Katia R. M., and Hallak, Jorge

Subjects
SERTOLI cells, LEYDIG cells, AUTOPSY, CELL adhesion molecules, VIRAL antigens
Abstract

Background: Multi‐organ damage is a common feature of severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) infection, going beyond the initially observed severe pneumonia. Evidence that the testis is also compromised is growing. Objective: To describe the pathological findings in testes from fatal cases of COVID‐19, including the detection of viral particles and antigens, and inflammatory cell subsets. Materials and methods: Postmortem testicular samples were obtained by percutaneous puncture from 11 deceased men and examined by reverse‐transcription polymerase chain reaction (RT‐PCR) for RNA detection and by light and electron microscopy (EM) for SARS‐CoV‐2. Immunohistochemistry (IHC) for the SARS‐CoV‐2 N‐protein and lymphocytic and histiocytic markers was also performed. Results: Eight patients had mild interstitial orchitis, composed mainly of CD68+ and TCD8+ cells. Fibrin thrombi were detected in five cases. All cases presented congestion, interstitial edema, thickening of the tubular basal membrane, decreased Leydig and Sertoli cells with reduced spermatogenesis, and strong expression of vascular cell adhesion molecule (VCAM) in vessels. IHC detected SARS‐Cov‐2 antigen in Leydig cells, Sertoli cells, spermatogonia, and fibroblasts in all cases. EM detected viral particles in the cytoplasm of fibroblasts, endothelium, Sertoli and Leydig cells, spermatids, and epithelial cells of the rete testis in four cases, while RT‐PCR detected SARS‐CoV‐2 RNA in three cases. Discussion and conclusion: The COVID‐19‐associated testicular lesion revealed a combination of orchitis, vascular changes, basal membrane thickening, Leydig and Sertoli cell scarcity, and reduced spermatogenesis associated with SARS‐CoV‐2 local infection that may impair hormonal function and fertility in men. [ABSTRACT FROM AUTHOR]

Published
2022
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11. Yellow fever and orthotopic liver transplantation: new insights from the autopsy room for an old but re‐emerging disease

Author

Duarte‐Neto, Amaro N, primary, Cunha, Marielton dos P, additional, Marcilio, Izabel, additional, Song, Alice T W, additional, Martino, Rodrigo B, additional, Ho, Yeh‐Li, additional, Pour, Shahab Z, additional, Dolhnikoff, Marisa, additional, Saldiva, Paulo H N, additional, Duarte, Maria I S, additional, Takakura, Cleusa F, additional, Lima, Fabiana R, additional, Tanigawa, Ryan Y, additional, Iglezias, Silvia D’A, additional, Kanamura, Cristina T, additional, Santos, Angela B G, additional, Perondi, Beatriz, additional, Zanotto, Paolo M de A, additional, D’Albuquerque, Luiz A C, additional, and Alves, Venancio A F, additional

Published
2019
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12. Comparative histopathologic and viral immunohistochemical studies on CeMV infection among Western Mediterranean, Northeast-Central, and Southwestern Atlantic cetaceans

Author

Díaz-Delgado, Josué, primary, Groch, Kátia R., additional, Sierra, Eva, additional, Sacchini, Simona, additional, Zucca, Daniele, additional, Quesada-Canales, Óscar, additional, Arbelo, Manuel, additional, Fernández, Antonio, additional, Santos, Elitieri, additional, Ikeda, Joana, additional, Carvalho, Rafael, additional, Azevedo, Alexandre F., additional, Lailson-Brito, Jose, additional, Flach, Leonardo, additional, Ressio, Rodrigo, additional, Kanamura, Cristina T., additional, Sansone, Marcelo, additional, Favero, Cíntia, additional, Porter, Brian F., additional, Centelleghe, Cinzia, additional, Mazzariol, Sandro, additional, Di Renzo, Ludovica, additional, Di Francesco, Gabriella, additional, Di Guardo, Giovanni, additional, and Catão-Dias, José Luiz, additional

Published
2019
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13. Comparative Immunopathology of Cetacean morbillivirus Infection in Free-Ranging Dolphins From Western Mediterranean, Northeast-Central, and Southwestern Atlantic

Author

Díaz-Delgado, Josué, primary, Groch, Kátia R., additional, Ressio, Rodrigo, additional, Riskallah, Isis P. J., additional, Sierra, Eva, additional, Sacchini, Simona, additional, Quesada-Canales, Óscar, additional, Arbelo, Manuel, additional, Fernández, Antonio, additional, Santos-Neto, Elitieri, additional, Ikeda, Joana, additional, Carvalho, Rafael Ramos de, additional, Azevedo, Alexandre de Freitas, additional, Lailson-Brito, Jose, additional, Flach, Leonardo, additional, Kanamura, Cristina T., additional, Fernandes, Natália C. C. A., additional, Cogliati, Bruno, additional, Centelleghe, Cinzia, additional, Mazzariol, Sandro, additional, Di Renzo, Ludovica, additional, Di Francesco, Gabriella, additional, Di Guardo, Giovanni, additional, and Catão-Dias, José Luiz, additional

Published
2019
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14. Comparative study of five commercial probes for the detection of Epstein-Barr virus (EBV) by in situ hybridization in cases of nodular sclerosis Hodgki's lymphoma

Author

Nonogaki, Suely, Shirata, Neuza K., Kimura, Lidia M., Guerra, Juliana M., Medeiros, Raphael S. S., Paes, Roberto Antonio P., Kanamura, Cristina T., Oliveira, Camila C., and Menezes, Yara de

Subjects
Hodgkin disease, doença de Hodgkin, in situ hybridization, infecções pelo vírus Epstein-Barr, Epstein-Barr virus infections, hibridização in situ
Abstract

Introduction: Epstein-Barr virus (EBV) may serve as a target in therapeutic treatments, thus reliable diagnostic results are necessary. Objective: The aim of this study was to evaluate the accuracy of EBV detection by in situ hybridization (ISH) using five commercial probes in formalin-fixed and paraffin-embedded samples of nodular sclerosis Hodgkin's lymphoma (HL), and to compare the results with immunohistochemistry (IHC) and polymerase chain reaction (PCR). Material and method: Thirty samples were selected, 28 were lymph nodes, one bone marrow and one mediastinum. The following parameters were analyzed: signal intensity; proportionality of positive cells; quality of the reaction according to comfort for evaluation, sign quality and homogeneity of labeled cells; background reaction; morphology; presence of artifacts; and positivity in other non-neoplastic cells. All samples were analyzed for EBV detection using the five probes, IHC for latent membrane protein type 1 (LMP1) and PCR for Epstein Barr virus nuclear antigen 1 (EBNA1). Statistical analyses were performed with the R1 software; Fleiss' test and Cohen Kappa index of 5% were considered significant. Results: The detection by IHC-LMP1 was 26.7% (8/30) and 66.7% (20/30) by PCR-EBNA1. All probes detected EBV. Positivity was observed in 42/90 (46.7%), 38/90 (42.2%), 45/90 (50%), 27/90 (30%) and 61/90 (67.8%) for probes A, B, C, D and E, respectively. Discussion: All five probes demonstrated positivity. Conclusion: Probe E showed better rate (67.8%), sensitivity, specificity and accuracy (100%), a very good correlation among the different observers and with PCR, besides great cost-benefits relation. RESUMO Introdução: O vírus Epstein-Barr (EBV) pode servir como alvo nos tratamentos terapêuticos, sendo necessário resultado diagnóstico confiável. Objetivo: Avaliar a acurácia da detecção do EBV pela hibridização in situ (ISH), utilizando cinco sondas comerciais em amostras fixadas em formalina e incluídas em parafina de linfoma de Hodgkin (LH) esclerose nodular, comparando os resultados com a imuno-histoquímica (IHQ) e a reação em cadeia pela polimerase (PCR). Material e método: Trinta amostras foram selecionadas, sendo 28 linfonodos, uma medula óssea e um mediastino. Os seguintes parâmetros foram analisados: intensidade do sinal; proporcionalidade das células positivas; qualidade da reação de acordo com o conforto na avaliação, qualidade do sinal e homogeneidade das células marcadas; reação de fundo; morfologia; presença de artefatos; e positividade em outras células não neoplásicas. Todas as amostras foram analisadas para a detecção do EBV usando as cinco sondas, IHQ para proteína da membrana latente tipo 1 (LMP1) e PCR para antígeno nuclear do EBV (EBNA1). As análises estatísticas foram realizadas com o software R1; os índices de 5% para Kappa de Fleiss e Cohen foram considerados significantes. Resultados: A detecção pela IHQ-LMP1 foi de 26,7% (8/30) e 66,7% (20/30) pela PCR-EBNA1. Todas as sondas detectaram EBV. A positividade foi observada em 42/90 (46,7%), 38/90 (42,2%), 45/90 (50%), 27/90 (30%) e 61/90 (67,8%) para as sondas A, B, C, D e E, respectivamente. Discussão: Todas as sondas demonstraram positividade. Conclusão: A sonda E mostrou melhor taxa (67,8%), sensibilidade, especificidade e precisão (100%), boa correlação entre os diferentes observadores e com a PCR, além de ótimo custo/benefício.

Published
2016

16. Comparative study of five commercial probes for the detection of Epstein-Barr virus (EBV) by in situ hybridization in cases of nodular sclerosis Hodgki’s lymphoma

Author

Nonogaki, Suely, primary, Shirata, Neuza K., additional, Kimura, Lidia M., additional, Guerra, Juliana M., additional, Medeiros, Raphael S. S., additional, Paes, Roberto Antonio P., additional, Kanamura, Cristina T., additional, Oliveira, Camila C., additional, and Menezes, Yara de, additional

Published
2016
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17. Fatal toxoplasmosis in a southern muriqui (<italic>Brachyteles arachnoides</italic>) from São Paulo state, Brazil: Pathological, immunohistochemical, and molecular characterization.

Author

Santos, Stéfanie Vanessa, Pena, Hilda F. J., Talebi, Mauricio G., Teixeira, Rodrigo H. F., Kanamura, Cristina T., Diaz‐Delgado, Josué, Gennari, Solange M., and Catão‐Dias, José Luiz

Subjects
TOXOPLASMOSIS in animals, SOUTHERN muriqui, IMMUNOHISTOCHEMISTRY, GENOTYPES, TOXOPLASMA gondii, PRIMATOLOGY
Abstract

Abstract: We report the pathological, immunohistochemical, and molecular features of fatal acute systemic toxoplasmosis in an adult, female, free‐living southern muriqui (Brachyteles arachnoides) from São Paulo state, Brazil. PCR‐RFLP genotyping analysis identified the #21 genotype of Toxoplasma gondii. This represents the first report of acute toxoplasmosis involving this genotype in humans and animals. [ABSTRACT FROM AUTHOR]

Published
2018
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18. Phylogeography of Rickettsia rickettsii Genotypes Associated with Fatal Rocky Mountain Spotted Fever

Author

Paddock, Christopher D., primary, Kanamura, Cristina T., additional, Liu, Lindy, additional, Pereira dos Santos, Fabiana C., additional, Angerami, Rodrigo N., additional, Bollweg, Brigid C., additional, Denison, Amy M., additional, Brasil Martines, Roosecelis, additional, Dahlgren, F. Scott, additional, Lash, R. Ryan, additional, and Karpathy, Sandor E., additional

Published
2014
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