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374 results on '"Kaminski, M."'

1. $^{22}$Na Activation Level Measurements of Fused Silica Rods in the LHC Target Absorber for Neutrals (TAN) Compared to FLUKA Simulations

Author

Yang, S., Gilarte, M. Sabate, Tate, A., Santiago, N., Longo, R., Mazzoni, S., Cerutti, F., Bravin, E., Perdekamp, M. Grosse, Lerner, G., Prelipcean, D., Citron, Z., Cole, B., Jackobsen, S., Kaminski, M. D., Koeth, T., Lantz, C., MacLean, D., Mignerey, A., Murray, M., Palm, M., Phipps, M., Steinberg, P., and Tsinganis, A.

Subjects
Physics - Accelerator Physics, Physics - Instrumentation and Detectors
Abstract

The Target Absorbers for Neutrals (TANs) are located in a high-intensity radiation environment inside the tunnel of the Large Hadron Collider (LHC). TANs are positioned about $140$ m downstream from the beam interaction points. Seven $40$ cm long fused silica rods with different dopant specifications were irradiated in the TAN by the Beam RAte of Neutrals (BRAN) detector group during $p$+$p$ data taking from 2016 to 2018 at the LHC. The peak dose delivered to the fused silica rods was $18$ MGy. We report measurements of the $^{22}$Na activation of the fused silica rods carried out at the University of Illinois at Urbana-Champaign and Argonne National Laboratory. At the end of the irradiation campaign, the maximum $^{22}$Na activity observed was $A=21$ kBq$/{\rm cm^3}$ corresponding to a density, $\rho= 2.5\times 10^{12} /{\rm cm^3}$, of $^{22}$Na nuclei. FLUKA Monte Carlo simulations have been performed by the CERN FLUKA team to estimate $^{22}$Na activities for the irradiated BRAN rod samples. The simulations reproduce the $^{22}$Na activity profile measured along the rods, with a 35% underestimation of the experimental measurement results., Comment: 11 pages, 14 figures, to be submitted to PRAB

Published
2022
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5. CRIS: A Novel Tool Described Using Only Three Self-Explanatory Words Performs Similarly To JNET Amongst Western Experts In The Detection Of Cancer And Determination Of Correct Treatment In Large Non-Pedunculated Colorectal Polyps

Author

Argenziano, M. E., additional, Debels, L., additional, Smeets, S., additional, Montori, M., additional, Poortmans, P. J., additional, Ridolfo, S., additional, Tornai, T., additional, Kaminski, M., additional, Lala, V., additional, Valori, R., additional, Anderson, J., additional, Bourke, M. J., additional, Desomer, L., additional, and Tate, D. J., additional

Published
2024
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6. Endoscopic full-thickness resection of duodenal neuroendocrine tumors using the Full-Thickness Resection Device (FTRD): Results from a large, retrospective, multicenter study

Author

Wannhoff, A., additional, Nabi, Z., additional, Moons, L.M. G., additional, Haber, G., additional, Ge, P., additional, Dertmann, T., additional, Deprez, P. H., additional, Bouvette, C., additional, Mueller, J., additional, grande, G., additional, Kaminski, M. F., additional, Kim, J.J. W., additional, Weich, A., additional, Bauerfeind, P., additional, George, J., additional, Pioche, M., additional, Mandarino, F. V., additional, Kouladouros, K., additional, Tribonias, G., additional, Boger, P., additional, Hayee, B., additional, Bilal, M., additional, Albers, S. C., additional, Leclercq, P., additional, Paspatis, G., additional, Caselitz, M., additional, Sharma, A., additional, Arulprakash, S., additional, Zachäus, M., additional, Irani, S., additional, Barret, M., additional, Hoare, J., additional, Denzer, U., additional, Moog, G., additional, Ebigbo, A., additional, and Caca, K., additional

Published
2024
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7. Endoscopic radiofrequency ablation versus hybrid argon plasma coagulation in the treatment of Barrett's esophagus – the patients' perspective: a randomized controlled trial assessing procedural acceptability and safety (the RATE study)

Author

Januszewicz, W., additional, Nastazja, D. P., additional, Wrońska, E., additional, Klimkowski, R., additional, Wojtowicz-Popiel, M., additional, Regula, J., additional, and Kaminski, M. F., additional

Published
2024
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8. Dense Nuclear Matter Equation of State from Heavy-Ion Collisions

Author

Sorensen, A, primary, Agarwal, K, additional, Brown, K, additional, Chajecki, Z, additional, Danielewicz, P, additional, Lynch, W, additional, Pratt, S, additional, Tsang, M, additional, Drischler, C, additional, Gandolfi, S, additional, Tews, I, additional, Holt, J, additional, Ko, C, additional, Kaminski, M, additional, Kumar, R, additional, Li, B, additional, Newton, W, additional, McIntosh, A, additional, Savchuk, O, additional, Vogt, R, additional, Wolter, H, additional, and Zbroszczyk, H, additional

Published
2023
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10. Updated NNLO QCD predictions for the weak radiative B-meson decays

Author

Misiak, M., Asatrian, H. M., Boughezal, R., Czakon, M., Ewerth, T., Ferroglia, A., Fiedler, P., Gambino, P., Greub, C., Haisch, U., Huber, T., Kaminski, M., Ossola, G., Poradzinski, M., Rehman, A., Schutzmeier, T., Steinhauser, M., and Virto, J.

Subjects
High Energy Physics - Phenomenology, High Energy Physics - Experiment
Abstract

Weak radiative decays of the B mesons belong to the most important flavor changing processes that provide constraints on physics at the TeV scale. In the derivation of such constraints, accurate standard model predictions for the inclusive branching ratios play a crucial role. In the current Letter we present an update of these predictions, incorporating all our results for the O(alpha_s^2) and lower-order perturbative corrections that have been calculated after 2006. New estimates of nonperturbative effects are taken into account, too. For the CP- and isospin-averaged branching ratios, we find B_{s gamma} = (3.36 +_ 0.23) * 10^-4 and B_{d gamma} = 1.73^{+0.12}_{-0.22} * 10^-5, for E_gamma > 1.6GeV. Both results remain in agreement with the current experimental averages. Normalizing their sum to the inclusive semileptonic branching ratio, we obtain R_gamma = ( B_{s gamma} + B_{d gamma})/B_{c l nu} = (3.31 +_ 0.22) * 10^-3. A new bound from B_{s gamma} on the charged Higgs boson mass in the two-Higgs-doublet-model II reads M_{H^+} > 480 GeV at 95%C.L., Comment: journal version, 5 pages, no figures

Published
2015
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12. Googling on Colonoscopy: A Retrospective Analysis of Search Engine Statistics

Author

Kaminski M, Marlicz W, and Koulaouzidis A

Subjects
colonoscopy, internet, google, trends, infodemiology, Diseases of the digestive system. Gastroenterology, RC799-869
Abstract

Mikolaj Kaminski,1 Wojciech Marlicz,2 Anastasios Koulaouzidis3 1District Hospital in Oborniki, Oborniki, Poland; 2Department of Gastroenterology, Pomeranian Medical University, Szczecin, Poland; 3Endoscopy Unit, The Royal Infirmary of Edinburgh, Scotland, Edinburgh, UKCorrespondence: Anastasios KoulaouzidisEndoscopy Unit, The Royal Infirmary of Edinburgh, 51 Little France Crescent, Edinburgh, Scotland EH16 4SA, United KingdomTel +44-131-2421603Fax +44-131-2421618Email akoulaouzidis@hotmail.comPurpose: Colonoscopy is a gold standard for screening and diagnosis of colorectal cancer (CRC). The data from the search engine may reveal what information on coloscopy gains the attention of Internet users. We aimed to investigate Google searches trends and terms related to colonoscopy.Patients and Methods: We retrieved statistics searches related to colonoscopy using Google Trends (GT) and Google Ads (GA) for the period from April 2016 to March 2020. The GT data was used for the analysis of time and regional search patterns worldwide. GA data for Australia, Canada, Ireland, New Zealand (NZ), Poland, the United Kingdom (UK), and the United States (US) were used to calculate the search volume of categories of queries related to colonoscopy.Results: Globally, the relative search volume on colonoscopy has increased until the COVID-19 outbreak and revealed seasonal variation: the highest interest was observed in March (CRC awareness month), and the lowest during December (Christmas holidays). The highest number of searches per 1000 Google users-years was done in Poland (59.62) and the lowest in the UK (19.46). Most commonly, Google users searched for details on colonoscopy techniques (Australia, Canada, Ireland, NZ), anesthesia during the procedure (Poland), facility performing colonoscopy (UK, US). In all seven countries, less than 2% of queries concerned with bowel preparation before the procedure.Conclusion: Before the COVID-19 pandemic, the interest in colonoscopy has increased among Google users. Google users may underestimate the importance of proper bowel preparation.Keywords: colonoscopy, internet, google, trends, infodemiology

Published
2020

16. A “FUNCTIONAL CURE” MAY BE ACHIEVABLE IN A SUBSET OF PATIENTS WITH FOLLICULAR LYMPHOMA TREATED WITH CHEMOIMMUNOTHERAPY: 15‐YEAR FOLLOW‐UP OF PHASE III SWOG‐S0016

Author

Shadman, M., primary, Li, H., additional, Rimsza, L., additional, Leonard, J. P., additional, Kaminski, M. S, additional, Spier, C. M, additional, Gopal, A. K, additional, Dakhil, S., additional, LeBlanc, M., additional, Smith, S. M., additional, and Friedberg, J. W, additional

Published
2023
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20. The interrelatedness of cognitive abilities in very preterm and full‐term born children at 5.5 years of age: a psychometric network analysis approach.

Author

Rapuc, S., Pierrat, V., Marchand‐Martin, L., Benhammou, V., Kaminski, M., Ancel, P.‐Y., and Twilhaar, E.S.

Subjects
MEMORY, PREMATURE infants, DURATION of pregnancy, INTELLIGIBILITY of speech, COGNITIVE processing speed, CHILD development, SOCIAL network analysis, PSYCHOMETRICS, COMPARATIVE studies, INTELLECT, VERBAL behavior, VISUAL perception, COGNITIVE testing, INTELLIGENCE tests, CHILDREN
Abstract

Background: Very preterm (VP) birth is associated with a considerable risk for cognitive impairment, putting children at a disadvantage in academic and everyday life. Despite lower cognitive ability on the group level, there are large individual differences among VP born children. Contemporary theories define intelligence as a network of reciprocally connected cognitive abilities. Therefore, intelligence was studied as a network of interrelated abilities to provide insight into interindividual differences. We described and compared the network of cognitive abilities, including strength of interrelations between and the relative importance of abilities, of VP and full‐term (FT) born children and VP children with below‐average and average‐high intelligence at 5.5 years. Methods: A total of 2,253 VP children from the EPIPAGE‐2 cohort and 578 FT controls who participated in the 5.5‐year‐follow‐up were eligible for inclusion. The WPPSI‐IV was used to measure verbal comprehension, visuospatial abilities, fluid reasoning, working memory, and processing speed. Psychometric network analysis was applied to analyse the data. Results: Cognitive abilities were densely and positively interconnected in all networks, but the strength of connections differed between networks. The cognitive network of VP children was more strongly interconnected than that of FT children. Furthermore, VP children with below average IQ had a more strongly connected network than VP children with average‐high IQ. Contrary to our expectations, working memory had the least central role in all networks. Conclusions: In line with the ability differentiation hypothesis, children with higher levels of cognitive ability had a less interconnected and more specialised cognitive structure. Composite intelligence scores may therefore mask domain‐specific deficits, particularly in children at risk for cognitive impairments (e.g., VP born children), even when general intelligence is unimpaired. In children with strongly and densely connected networks, domain‐specific deficits may have a larger overall impact, resulting in lower intelligence levels. [ABSTRACT FROM AUTHOR]

Published
2024
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21. Successes and challenges installing the first proprietary closed-coke slurry system

Author

Kaminski, M., Manral, V., Heeswijk, B. V., Graeter, F., and v, S.

Subjects
Volatile organic compounds -- Waste management, Coal-water fuel -- Waste management, Coal slurry -- Waste management, Business, Petroleum, energy and mining industries
Abstract

The authors' company (a) licensed a twodrum delayed coking technology process unit to Grupa LOTOS in Gdansk, Poland. At the engineering design stage of the project, a closed-coke handling system [...]

Published
2021

22. Abdominal desmoid tumours after colectomy and ileorectal anastomosis versus proctocolectomy and ileal pouch-anal anastomosis in familial adenomatous polyposis

Author

Aelvoet, A., additional, Pellisé, M., additional, Miedema, T., additional, Bastiaansen, B.A. J., additional, Van Leerdam, M., additional, Jover, R., additional, Balaguer, F., additional, Kaminski, M. F., additional, Hompes, R., additional, Bossuyt, P.M. M., additional, Ricciardiello, L., additional, Karstensen, J. G., additional, Latchford, A., additional, and Dekker, E., additional

Published
2023
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23. WESTern outcomes of circumferential Endoscopic submucosal dissection for Oesophageal Squamous cell carcinoma – WESTEROS study

Author

de Santiago, E. Rodriguez, additional, Deprez, P., additional, Bourke, M. J., additional, Mathieu, P., additional, Pouw, R. E., additional, Seewald, S., additional, Barreiro, P., additional, Lemmers, A., additional, Ricardo, K., additional, Libanio, D., additional, Uchima, H., additional, de Frutos, D., additional, Alberto, H.D. T., additional, Kaminski, M., additional, Felipe, R. Z., additional, Bergman, J., additional, Adolfo, P., additional, Bas, W., additional, Andreia, C., additional, Nastazja, D. P., additional, Groth, S., additional, Vladyslav, Y., additional, Franco, A. R., additional, Sunil, G., additional, Jacques, J., additional, Ponchon, T., additional, Rivory, J., additional, Frederic, M., additional, Santos-Antunes, J., additional, Albéniz, E., additional, Alanna, E., additional, Messmann, H., additional, Wallenhorst, T., additional, Andreas, P., additional, Beatriz, P., additional, Sofía, P., additional, Noor, M., additional, Catarina, F., additional, Myriam, A., additional, Pedro, T., additional, Muhammad, A. A., additional, Ewerton, M. M., additional, Belkhir, S., additional, and Mario, D. R., additional

Published
2023
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24. Risk of cancer following colectomy with ileorectal/ileosigmoidal anastomosis and proctocolectomy with ileal pouch-anal anastomosis in familial adenomatous polyposis

Author

Bouchiba, H., additional, Aelvoet, A. S., additional, Pellisé, M., additional, Bastiaansen, B.A. J., additional, Van Leerdam, M. E., additional, Balaguer, F., additional, Kaminski, M. F., additional, Hompes, R., additional, Bossuyt, P.M. M., additional, Ricciardiello, L., additional, Jover, R., additional, Karstensen, J. G., additional, Latchford, A., additional, and Dekker, E., additional

Published
2023
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25. Clinical validation of a computer-aided detection model for colorectal polyp detection (CAD-ARTIPOD) trial using a second observer and real-time unblinding

Author

Sinonquel, P., additional, Eelbode, T., additional, Pech, O., additional, De Wulf, D., additional, Dewint, P., additional, Neumann, H., additional, Antonelli, G., additional, Tate, D. J., additional, Lemmers, A., additional, Pilonis, N. D., additional, Kaminski, M. F., additional, Demedts, I., additional, Hassan, C., additional, Roelandt, P., additional, Maes, F., additional, and Bisschops, R., additional

Published
2023
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26. Cold snare polypectomy for duodenal adenomas in familial adenomatous polyposis: a prospective international cohort study

Author

Aelvoet, A., additional, Karstensen, J. G., additional, Bastiaansen, B.A. J., additional, Van Leerdam, M., additional, Balaguer, F., additional, Kaminski, M. F., additional, Hompes, R., additional, Bossuyt, P.M. M., additional, Ricciardiello, L., additional, Latchford, A., additional, Jover, R., additional, Daca-Alvarez, M., additional, Pellisé, M., additional, and Dekker, E., additional

Published
2023
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27. T.12.4 REAL-TIME COMPUTER-AIDED DETECTION OF COLORECTAL NEOPLASIA DURING COLONOSCOPY: SYSTEMATIC REVIEW AND META-ANALYSIS

Author

Spadaccini, M., primary, Hassan, C., additional, De Marco, A., additional, Mori, Y., additional, Facciorusso, A., additional, Gkolfakis, P., additional, Tziatzios, G., additional, Triantafyllou, K., additional, Antonelli, G., additional, Khalaf, K., additional, Rizkala, T., additional, Bretthauer, M., additional, Vandvik, P.O., additional, Foroutan, F., additional, Fugazza, A., additional, Rondonotti, E., additional, Glissen-Brown, J., additional, Kamba, S., additional, Correale, L., additional, Bhandari, P., additional, Bisschops, R., additional, Dekker, E., additional, Kaminski, M., additional, Jover, R., additional, Saito, Y., additional, Sharma, P., additional, Rex, D., additional, and Repici, A., additional

Published
2023
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29. Effect of Intra- and Extrauterine Growth on Long-Term Neurologic Outcomes of Very Preterm Infants

Author

Larroque, B., Ancel, P.Y., Blondel, B., Bréart, G., Dehan, M., Garel, M., Kaminski, M., Maillard, F., du Mazaubrun, C., Missy, P., Sehili, F., Supernant, K., Marchand, L., Durand, M., Matis, J., Messer, J., Treisser, A., Burguet, A., Abraham-Lerat, L., Menget, A., Roth, P., Schaal, J.-P., Thiriez, G., Leveque, C., Marret, S., Marpeau, L., Boulot, P., Cambonie, G., Picaud, J.-C., Donadio, A.M., Ledesert, B., André, M., Fresson, J., Hascoët, J.M., Arnaud, C., Grandjean, H., Rolland, M., Fily, A., Ego, A., Outtier, M.L., Pierrat, V., Subtil, D., Truffert, P., Boog, G., Rouger-Bureau, V., Rozé, J.-C., Zupan-Simunek, V., Vodovar, M., Voyer, M., Guellec, Isabelle, Lapillonne, Alexandre, Marret, Stephane, Picaud, Jean-Charles, Mitanchez, Delphine, Charkaluk, Marie-Laure, Fresson, Jeanne, Arnaud, Catherine, Flamand, Cyril, Cambonie, Gilles, Kaminski, Monique, Roze, Jean-Christophe, and Ancel, Pierre-Yves

Published
2016
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33. P788 Endoscopic management of patients with high-risk colorectal colitis-associated neoplasia: a Delphi study

Author

Bak, M, primary, Albéniz, E, additional, East, J, additional, Coelho-Prabhu, N, additional, Suzuki, N, additional, Saito, Y, additional, Matsumoto, T, additional, Banerjee, R, additional, Kaminski, M, additional, Kiesslich, R, additional, Coron, E, additional, de Vries, A, additional, van der Woude, C J, additional, Bisschops, R, additional, Hart, A, additional, Itzkowitz, S, additional, Pioche, M, additional, Moons, L, additional, and Oldenburg, B, additional

Published
2023
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38. To which extent social withdrawal at the age of 1 year is associated with IQ at 5–6 years old? Results of the EDEN mother–child cohort

Author

Guedeney, Antoine, Doukhan, Sarah, Forhan, Anne, Heude, Barbara, Peyre, Hugo, Annesi-Maesano, I., Bernard, J. Y., Botton, J., Charles, M. A., Dargent-Molina, P., de Lauzon-Guillain, B., Ducimetière, P., de Agostini, M., Foliguet, B., Forhan, A., Fritel, X., Germa, A., Goua, V., Hankard, R., Heude, B., Kaminski, M., Larroque, B., Lelong, N., Lepeule, J., Magnin, G., Marchand, L., Nabet, C., Pierre, F., Slama, R., Saurel-Cubizolles, M. J., Schweitzer, M., Thiebaugeorges, O., and On behalf of the EDEN Mother–Child Cohort Study Group

Published
2017
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40. Na22 activation level measurements of fused silica rods in the LHC target absorber for neutrals compared to simulations

Author

Yang, S., primary, Gilarte, M. Sabate, additional, Tate, A., additional, Santiago, N., additional, Longo, R., additional, Mazzoni, S., additional, Cerutti, F., additional, Bravin, E., additional, Perdekamp, M. Grosse, additional, Lerner, G., additional, Prelipcean, D., additional, Citron, Z., additional, Cole, B., additional, Jackobsen, S., additional, Kaminski, M. D., additional, Koeth, T., additional, Lantz, C., additional, MacLean, D., additional, Mignerey, A., additional, Murray, M., additional, Palm, M., additional, Phipps, M., additional, Steinberg, P., additional, and Tsinganis, A., additional

Published
2022
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45. The Colon Endoscopic Bubble Scale (CEBuS): A two-phase evaluation study

Author

Taveira, F., Hassan, Cesare, Kaminski, M. F., Ponchon, T., Benamouzig, R., Bugajski, M., De Castelbajac, F., Cesaro, Paola, Chergui, H., Goran, L., Minelli Grazioli, L., Janicko, M., Januszewicz, W., Lamonaca, L., Lenz, J., Negreanu, L., Repici, A., Spada, Cristiano, Spadaccini, M., State, M., Szlak, J., Veseliny, E., Dinis-Ribeiro, M., Areia, M., Hassan C., Cesaro P., Spada C. (ORCID:0000-0002-5692-0960), Taveira, F., Hassan, Cesare, Kaminski, M. F., Ponchon, T., Benamouzig, R., Bugajski, M., De Castelbajac, F., Cesaro, Paola, Chergui, H., Goran, L., Minelli Grazioli, L., Janicko, M., Januszewicz, W., Lamonaca, L., Lenz, J., Negreanu, L., Repici, A., Spada, Cristiano, Spadaccini, M., State, M., Szlak, J., Veseliny, E., Dinis-Ribeiro, M., Areia, M., Hassan C., Cesaro P., and Spada C. (ORCID:0000-0002-5692-0960)

Abstract

Background To date, no scale has been validated to assess bubbles associated with bowel preparation. This study aimed to develop and assess the reliability of a novel scale - the Colon Endoscopic Bubble Scale (CEBuS). Methods This was a multicenter, prospective, observational study with two online evaluation phases of 45 randomly distributed still colonoscopy images (15 per scale grade). Observers assessed images twice, 2 weeks apart, using CEBuS (CEBuS-0 - no or minimal bubbles, covering<5% of the surface; CEBuS-1 - bubbles covering 5%-50%; CEBuS-2 - bubbles covering >50%) and reporting the clinical action (do nothing; wash with water; wash with simethicone). Results CEBuS provided high levels of agreement both in evaluation Phase 1 (4 experts) and Phase 2 (6 experts and 13 non-experts), with almost perfect intraobserver reliability: kappa 0.82 (95% confidence interval 0.75-0.88) and 0.86 (0.85-0.88); interobserver agreement - intraclass correlation coefficient (ICC) 0.83 (0.73-0.89) and 0.90 (0.86-0.94). Previous endoscopic experience had no influence on agreement among experts vs. non-experts: kappa 0.86 (0.80-0.91) vs. 0.87 (0.84-0.89) and ICC 0.91 (0.87-0.94) vs. 0.90 (0.86-0.94), respectively. Interobserver agreement on clinical action was ICC 0.63 (0.43-0.78) in Phase 1 and 0.77 (0.68-0.84) in Phase 2.Absolute agreement on clinical action per scale grade was 85% (82-88) for CEBuS-0, 21% (16-26) for CEBuS-1, and 74% (70-78) for CEBuS-2. Conclusion CEBuS proved to be a reliable instrument to standardize the evaluation of colonic bubbles during colonoscopy. Assessment in daily practice is warranted.

Published
2022

47. Antibiotic prophylaxis in preterm premature rupture of membranes at 24–31 weeks’ gestation: Perinatal and 2‐year outcomes in the EPIPAGE‐2 cohort

Author

Lorthe, Elsa, Letouzey, Mathilde, Torchin, Héloïse, Foix L'Helias, Laurence, Gras‐le Guen, Christèle, Benhammou, Valérie, Boileau, Pascal, Charlier, Caroline, Kayem, Gilles, Ancel, Pierre‐yves, Arnaud, Catherine, Blanc, Julie, Debillon, Thierry, Delorme, Pierre, D’ercole, Claude, Desplanches, Thomas, Diguisto, Caroline, Gascoin, Géraldine, Gire, Catherine, Goffinet, François, Langer, Bruno, Maisonneuve, Emeline, Marret, Stéphane, Monier, Isabelle, Morgan, Andrei, Rozé, Jean‐christophe, Schmitz, Thomas, Sentilhes, Loïc, Subtil, Damien, Tosello, Barthélémy, Vayssière, Christophe, Winer, Norbert, Zeitlin, Jennifer, Astruc, D, Kuhn, P, Matis, J, Ramousset, C, Hernandorena, X, Chabanier, P, Joly‐pedespan, L, Costedoat, Mj, Leguen, A, Lecomte, B, Lemery, D, Vendittelli, F, Beucher, G, Dreyfus, M, Guillois, B, Toure, Y, Burguet, A, Couvreur, S, Gouyon, Jb, Sagot, P, Colas, N, Sizun, J, Beuchée, A, Pladys, P, Rouget, F, Dupuy, Rp, Soupre, D, Charlot, F, Roudaut, S, Favreau, A, Saliba, E, Reboul, L, Bednarek, N, Morville, P, Verrière, V, Thiriez, G, Balamou, C, Marpeau, L, Barbier, C, Durrmeyer, X, Granier, M, Ayoubi, M, Baud, O, Carbonne, B, Jarreau, Ph, Mitanchez, D, Duffaut, C, Cornu, L, Moras, R, Boulot, P, Cambonie, G, Daudé, H, Badessi, A, Tsaoussis, N, Bédu, A, Mons, F, Bahans, C, Binet, Mh, Fresson, J, Hascoët, Jm, Milton, A, Morel, O, Vieux, R, Hilpert, L, Alberge, C, Baron, M, Charkaluk, Ml, Pierrat, V, Truffert, P, Akowanou, S, Simeoni, U, Bongain, A, Deschamps, M, Branger, B, Rouger, V, Dupont, C, Gondry, Jean, Krim, G, Baby, B, Debeir, M, Claris, O, Picaud, Jc, Rubio‐gurung, S, Cans, C, Ego, A, Patural, H, Rannaud, A, Janky, E, Poulichet, A, Rosenthal, Jm, Coliné, E, Favre, A, Joly, N, Châlons, S, Pignol, J, Laurence, Pl, Robillard, Py, Samperiz, S, Ramful, D, Blondel, B, Bonet, M, Brinis, A, Coquelin, A, Durox, M, Kaminski, M, Khemache, K, Khoshnood, B, Lebeaux, C, Marchand‐martin, L, Rousseau, J, Saurel‐cubizolles, Mj, Tran, D, Centre de Recherche Épidémiologie et Statistique Sorbonne Paris Cité (CRESS (U1153 / UMR_A_1125 / UMR_S_1153)), Conservatoire National des Arts et Métiers [CNAM] (CNAM), HESAM Université - Communauté d'universités et d'établissements Hautes écoles Sorbonne Arts et métiers université (HESAM)-HESAM Université - Communauté d'universités et d'établissements Hautes écoles Sorbonne Arts et métiers université (HESAM)-Université Sorbonne Paris Cité (USPC)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Centre hospitalier intercommunal de Poissy/Saint-Germain-en-Laye - CHIPS [Poissy], Université de Versailles Saint-Quentin-en-Yvelines - UFR Sciences de la santé Simone Veil (UVSQ Santé), Université de Versailles Saint-Quentin-en-Yvelines (UVSQ), AP-HP - Hôpital Cochin Broca Hôtel Dieu [Paris], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Centre hospitalier universitaire de Nantes (CHU Nantes), Equipe 1 : EPOPé - Épidémiologie Obstétricale, Périnatale et Pédiatrique (CRESS - U1153), HESAM Université - Communauté d'universités et d'établissements Hautes écoles Sorbonne Arts et métiers université (HESAM)-HESAM Université - Communauté d'universités et d'établissements Hautes écoles Sorbonne Arts et métiers université (HESAM)-Université Sorbonne Paris Cité (USPC)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Conservatoire National des Arts et Métiers [CNAM] (CNAM), Unité de Parasitologie-Mycologie, Service de Microbiologie [Hôpital Necker-Enfants-Malades, Paris], Assistance Publique - Hôpitaux de Paris, CHU Trousseau [APHP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), Service Epidémiologie clinique et santé publique [CHU Toulouse], Pôle Santé publique et médecine publique [CHU Toulouse], Centre Hospitalier Universitaire de Toulouse (CHU Toulouse)-Centre Hospitalier Universitaire de Toulouse (CHU Toulouse), Unité de biostatistiques [Centre Georges-François Leclerc], Centre Régional de Lutte contre le cancer Georges-François Leclerc [Dijon] (UNICANCER/CRLCC-CGFL), UNICANCER-UNICANCER, Médecine Néonatale et Réanimation Pédiatrique CHU Grenoble, CHU Grenoble, Service de gynécologie-obstétrique [Hôpital Nord - APHM], Aix Marseille Université (AMU)-Assistance Publique - Hôpitaux de Marseille (APHM)- Hôpital Nord [CHU - APHM], Service de Gynécologie Obstétrique, Médecine Foetale et Stérilité Conjugale - Chirurgie Gynécologie et Oncologique [CHU de Dijon], Centre Hospitalier Universitaire de Dijon - Hôpital François Mitterrand (CHU Dijon), Centre Hospitalier Universitaire d'Angers (CHU Angers), PRES Université Nantes Angers Le Mans (UNAM), Service de Néonatologie, Assistance Publique - Hôpitaux de Marseille (APHM)- Hôpital Nord [CHU - APHM], Recherches épidémiologiques en santé périnatale et santé des femmes, Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut National de la Santé et de la Recherche Médicale (INSERM), Physiopathologie des Adaptations Nutritionnelles (PhAN), Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Nantes Université - UFR de Médecine et des Techniques Médicales (Nantes Univ - UFR MEDECINE), Nantes Université - pôle Santé, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes Université - pôle Santé, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ), Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier), Université de Montpellier (UM), Groupe de Recherche sur l'Analyse Multimodale de la Fonction Cérébrale - UMR INSERM_S 1105 (GRAMFC), Université de Picardie Jules Verne (UPJV)-CHU Amiens-Picardie-Institut National de la Santé et de la Recherche Médicale (INSERM), CHU Amiens-Picardie, Funding information:This work was partly supported by a postdoctoral grant from the Fondation des Treilles to EL. EPIPAGE-2 was funded by the French Institute of Public Health Research (IRESP TGIR 2009-01 programme)/Institute of Public Health and its partners: the French Health Ministry, the National Institute of Health and Medical Research (INSERM), the National Institute of Cancer, and the National Solidarity Fund for Autonomy (CNSA), the National Research Agency through the French EQUIPEX programme of investments for the future (grant number ANR-11-EQPX-0038), and the PREMUP Foundation. Additional funding was obtained from Fondation pour la Recherche Medicale (grant number SPF 20160936356) and Fondation de France (grant numbers 00050329, Grand Prix R18202KK]). The funders had no role in the study design, data collection and analysis, decision to publish, or preparation of the manuscript., ANR-11-EQPX-0038,RE-CO-NAI,Plateforme de REcherche sur les COhortes d'enfants suivis depuis la NAIssance(2011), Centre d'Epidémiologie et de Recherche en santé des POPulations (CERPOP), Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut National de la Santé et de la Recherche Médicale (INSERM), Centre Hospitalier Universitaire de Toulouse (CHU Toulouse), Education, Formation, Travail, Savoirs (EFTS), Université Toulouse - Jean Jaurès (UT2J), Université de Toulouse (UT)-Université de Toulouse (UT)-École Nationale Supérieure de Formation de l'Enseignement Agricole de Toulouse-Auzeville (ENSFEA), École Nationale Supérieure de Formation de l'Enseignement Agricole de Toulouse-Auzeville (ENSFEA), Centre Hospitalier Universitaire [Grenoble] (CHU), Modélisation et Évaluation des données complexes en Santé Publique (TIMC-MESP), Translational Innovation in Medicine and Complexity / Recherche Translationnelle et Innovation en Médecine et Complexité - UMR 5525 (TIMC ), VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement (VAS)-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes (UGA)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP ), Université Grenoble Alpes (UGA)-VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement (VAS)-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes (UGA)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP ), Université Grenoble Alpes (UGA), CHU Dijon, Hôpital Nord [CHU - APHM], Centre d'études et de recherche sur les services de santé et la qualité de vie (CEReSS), Aix Marseille Université (AMU), Department of Obstetrics and Gynecology, Les Hôpitaux Universitaires de Strasbourg (HUS), EPIPAGE-2 Study Group, and Institut National de la Santé et de la Recherche Médicale (INSERM)

Subjects
Fetal Membranes, Premature Rupture, obstetric intervention, [SDV]Life Sciences [q-bio], Gestational Age, antenatal management, Cohort Studies, Pregnancy, Escherichia coli, Humans, Prospective Studies, latency, amoxicillin, neurodevelopment, macrolides, prematurity, Infant, Newborn, Pregnancy Outcome, Obstetrics and Gynecology, Infant, prophylactic antibiotics, Antibiotic Prophylaxis, Anti-Bacterial Agents, perinatal outcome, cephalosporins, Premature Birth, Female, [SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie, Neonatal Sepsis, Infant, Premature
Abstract

To compare different antibiotic prophylaxis administered after preterm premature rupture of membranes to determine whether any were associated with differences in obstetric and/or neonatal outcomes and/or neurodevelopmental outcomes at 2 years of corrected age.Prospective, nationwide, population-based EPIPAGE-2 cohort study of preterm infants.France, 2011.We included 492 women with a singleton pregnancy and a diagnosis of preterm premature rupture of membranes at 24-31 weeks. Exclusion criteria were contraindication to expectant management or indication for antibiotic therapy other than preterm premature rupture of membranes. Antibiotic prophylaxis was categorised as amoxicillin (n = 345), macrolide (n = 30), third-generation cephalosporin (n = 45) or any combinations covering Streptococcus agalactiae and90% of Escherichia coli (n = 72), initiated within 24 hours after preterm premature rupture of membranes.Population-averaged robust Poisson models.Survival at discharge without severe neonatal morbidity, 2-year neurodevelopment.With amoxicillin, macrolide, third-generation cephalosporin and combinations, 78.5%, 83.9%, 93.6% and 86.0% of neonates were discharged alive without severe morbidity. The administration of third-generation cephalosporin or any E. coli-targeting combinations was associated with improved survival without severe morbidity (adjusted risk ratio 1.25 [95% confidence interval 1.08-1.45] and 1.10 [95 % confidence interval 1.01-1.20], respectively) compared with amoxicillin. We evidenced no increase in neonatal sepsis related to third-generation cephalosporin-resistant pathogen.In preterm premature rupture of membranes at 24-31 weeks, antibiotic prophylaxis based on third-generation cephalosporin may be associated with improved survival without severe neonatal morbidity when compared with amoxicillin, with no evidence of increase in neonatal sepsis related to third-generation cephalosporin-resistant pathogen.Antibiotic prophylaxis after PPROM at 24-31 weeks: 3rd-generation cephalosporins associated with improved neonatal outcomes.

Published
2022

48. Early skin-to-skin contact and neurodevelopmental outcome at 5 years in very preterm infants: the Epipage-2 cohort study

Author

Mitha A, Marchand L, Rozé JC, Kuhn P, Kaminski M, and Pierrat V

Abstract

BACKGROUND AND AIMS Long-term effects on neurodevelopment of Skin-to-Skin Contact (SSC) for very preterm infants are still debated. This study aims to evaluate the association of early SSC on neurodevelopmental outcomes at 5½ years among very preterm infants. METHODS Using the national population based EPIPAGE-2 cohort, exposure to SSC during the first week of life was evaluated by a propensity score analysis, based on individual and unit characteristics with inverse probability of treatment weighting approach. Outcomes were full-scale-intelligence-quotient (Wechsler Preschool and Primary Scale of Intelligence, 4th edition); behaviour (strengths and difficulties questionnaire); and social communication difficulties (social communication questionnaire) among 2561 infants born between 24 and 31 weeks, and surviving at 5½ years. RESULTS Among survivors, 1581 (61.8%) were exposed to SSC during the first week of life (range among neonatal units from 15 to 75%). At 5½ years, SSC was associated with an increased full-scale-intelligence-quotient +1.8 points (+0.0 to +3.6); and with trends for lower scores of behavioural difficulties -0.4 points (-1.1 to +0.4) and social communication difficulties -0.3 points (-0.8 to 0.2). CONCLUSIONS Early SSC during the first week of life among very preterm infants was associated with increased full-scale-intelligence-quotient at 5½ years. Variability of practices among units deserves attention. Further evaluation of the dose-effect is needed.

Published
2022
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50. Mild Adverse Events of Sputnik V Vaccine Extracted from Russian Language Telegram Posts via BERT Deep Learning Model

Author

Alexander Semenov, Belik, Andrzej Jarynowski, and Kaminski M

Subjects
Russian language, medicine.medical_specialty, Coronavirus disease 2019 (COVID-19), Nausea, business.industry, Vector vaccine, Infodemiology, Internal medicine, medicine, Vomiting, Chills, medicine.symptom, Adverse effect, business
Abstract

BackgroundThere is a limited amount of data on the COVID-19 vector vaccine Gam-COVID-Vac (Sputnik V) safety profile. Previous infodemiology studies showed that social media discourse could be analyzed to assess the most concerning adverse events (AE) caused by drugs.ObjectiveWe aimed to investigate mild AEs of Sputnik V based on a participatory trial conducted on Telegram in the Russian language. We compared AEs extracted from Telegram with other limited databases on Sputnik V and other COVID-19 vaccines. We explored symptom co-occurrence patterns and determined how counts of administered doses, age, gender, and sequence of shots could confound the reporting of AEs.Materials and MethodsWe collected a unique dataset consisting of 11,515 self-reported Sputnik V vaccine AEs posted on the Telegram group, and we utilized natural language processing methods to extract AEs. Specifically, we performed multi-label classifications using the deep neural language model BERT “DeepPavlov”, which we pre-trained on a Russian language corpus and applied to the Telegram messages. The resulting AUC score was 0.991. We chose symptom classes that represented the following AEs: fever, pain, chills, fatigue, nausea/vomiting, headache, insomnia, lymph node enlargement, erythema, pruritus, swelling, and diarrhea.ResultsThe results of the retrospective analysis showed that females reported more AEs than males (1.2-fold, Pβ = .05 per year, PThe Lancet. However, the AEs reported in Telegram posts were consistent (Pearson correlation r=.94, P=.02) with those reported in the Argentinian post-marketing AE registry.ConclusionAfter receiving the Sputnik V vaccination, Telegram users complained about pain (47%), fever (47%), fatigue (34%), and headache (25%). The results showed that the AE profile of Sputnik V was comparable with other COVID-19 vaccines. Examining the sentinel properties of participatory trials (which is subject to self-reporting biases) could still provide meaningful information about pharmaceutics, especially if only a limited amount of information on AEs is provided by producers.

Published
2021

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