252 results on '"Kai, Hirofumi"'
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2. Correction: The 2019 and 2021 International workshops on Alport syndrome
3. Combinatorial screening for therapeutics in ATTRv amyloidosis identifies naphthoquinone analogues as TTR-selective amyloid disruptors
4. Metformin suppresses epithelial sodium channel hyperactivation and its associated phenotypes in a mouse model of obstructive lung diseases
5. NanoLuc reporters identify COL4A5 nonsense mutations susceptible to drug-induced stop codon readthrough
6. The 2019 and 2021 International Workshops on Alport Syndrome
7. Nitric oxide facilitates the targeting Kupffer cells of a nano-antioxidant for the treatment of NASH
8. Type IV Collagen Variants in CKD: Performance of Computational Predictions for Identifying Pathogenic Variants
9. Intrapopulation analysis of longitudinal lifespan in Caenorhabditis elegans identifies W09D10.4 as a novel AMPK-associated healthspan shortening factor
10. Trimerization and Genotype–Phenotype Correlation of COL4A5 Mutants in Alport Syndrome
11. Erratum to “Dietary state and impact of DMSO on Caenorhabditis elegans aging: Insights from healthspan analysis”[Biochem. Biophys. Res. Commun. (742),2025, 151156]
12. Dietary state and impact of DMSO on Caenorhabditis elegans aging: Insights from healthspan analysis
13. TALENs Facilitate Single-step Seamless SDF Correction of F508del CFTR in Airway Epithelial Submucosal Gland Cell-derived CF-iPSCs
14. Metformin ameliorates the severity of experimental Alport syndrome
15. Pathopharmacological Evaluation of Bakumondo-To (Mai-Men-Dong-Tang) as a Curative for Chronic Inflammatory Airway Diseases
16. A cell-based high-throughput screening method to directly examine transthyretin amyloid fibril formation at neutral pH
17. Auto-measure emphysematous parameters and pathophysiological gene expression profiles in experimental mouse models of acute and chronic obstructive pulmonary diseases
18. T3 Intratracheal Therapy Alleviates Pulmonary Pathology in an Elastase-Induced Emphysema-Dominant COPD Mouse Model
19. The effect of Porphyromonas gingivalis on inflammatory pathology in normal or COPD airway
20. 6-Formylindolo[3,2-b]Carbazole Accelerates Skin Wound Healing via Activation of ERK, but Not Aryl Hydrocarbon Receptor
21. Mild electrical stimulation with heat shock attenuates renal pathology in adriamycin-induced nephrotic syndrome mouse model
22. Development of an exon skipping therapy for X-linked Alport syndrome with truncating variants in COL4A5
23. The DsbA-L gene is associated with respiratory function of the elderly via its adiponectin multimeric or antioxidant properties
24. Melinjo seed extract increases adiponectin multimerization in physiological and pathological conditions
25. T 3 Intratracheal Therapy Alleviates Pulmonary Pathology in an Elastase-Induced Emphysema-Dominant COPD Mouse Model.
26. CyclosporinA Derivative as Therapeutic Candidate for Alport Syndrome by Inducing Mutant Type IV Collagen Secretion
27. Endoplasmic Reticulum (ER) Stress Induces Sirtuin 1 (SIRT1) Expression via the PI3K-Akt-GSK3β Signaling Pathway and Promotes Hepatocellular Injury
28. Pre-emptive Quality Control Protects the ER from Protein Overload via the Proximity of ERAD Components and SRP
29. Cross-talk between PKA-Cβ and p65 mediates synergistic induction of PDE4B by roflumilast and NTHi
30. Correction: The 2019 and 2021 International workshops on Alport syndrome
31. Apelin は Elastase 誘導性肺気腫モデルマウスにおいて肺炎症を抑制し COPD 病態を改善する
32. Hydrogen bonds connecting the N-terminal region and the DE loop stabilize the monomeric structure of transthyretin.
33. Long-term treatment with EGFR inhibitor erlotinib attenuates renal inflammatory cytokines but not nephropathy in Alport syndrome mouse model
34. Free radical scavenging, α-glucosidase inhibitory and lipase inhibitory activities of eighteen Sudanese medicinal plants
35. Negative Cross-Talk between TLR2/4-Independent AMPKα1 and TLR2/4-Dependent JNK Regulates S. pneumoniae–Induced Mucosal Innate Immune Response
36. Cellular stress response pathways and diabetes mellitus
37. A Splice Switch in SIGIRR Causes a Defect of IL-37-Dependent Anti-Inflammatory Activity in Cystic Fibrosis Airway Epithelial Cells
38. Novel Keap1-Nrf2 Protein-Protein Interaction Inhibitor UBE-1099 Ameliorates Progressive Phenotype in Alport Syndrome Mouse Model
39. Seamless Gene Correction in the Human Cystic Fibrosis Transmembrane Conductance Regulator Locus by Vector Replacement and Vector Insertion Events
40. Seamless Gene Correction in the Human Cystic Fibrosis Transmembrane Conductance Regulator Locus by Vector Replacement and Vector Insertion Events
41. Elucidation of interaction factors between COPD and lung cancer
42. Mild electrical stimulation and heat shock can suppress acute kidney injury (AKI) to chronic kidney disease (CKD) transition
43. Identification of W09D10.4/PPTC7 as a novel AMPK-associated healthspan modulatory factor by using C. elegans Healthspan Auto-monitoring System (C-HAS)
44. The effect of intratracheal administration of thyroid hormone (T3) in chronic obstructive pulmonary disease (COPD) mouse model simulating disease type classification.
45. Efficacy of Keap1-Nrf2 protein-protein interaction inhibitor for glomerulosclerosis in mouse model of chronic kidney disease
46. Utilizing split-luciferase-based HTS platform and natural product extracts library yielded cyclosporin A as candidate drug for Alport syndrome
47. Clinical trial recommendations for potential Alport syndrome therapies
48. Intratracheal GLP-1 receptor agonist treatment up-regulates mucin via p38 and exacerbates emphysematous phenotype in mucus hypersecretory obstructive lung diseases
49. Aminoglycoside-induced premature termination codon readthrough of COL4A5 nonsense mutations that cause Alport syndrome
50. Differential mode of cholesterol inclusion with 2‐hydroxypropyl‐cyclodextrins increases safety margin in treatment of Niemann‐Pick disease type C
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