Search

Granulation is a technique that convert fine powder particles to granules which form appropriate agglomerate. It’s main function is to improve the powders flow and compressibility properties as well as to prevent segregation of the blend components. Traditionally, there are three types of granulation methods namely dry granulation, wet granulation and direct compressing. But, each one of these traditional methods has different disadvantage which prompted the researchers to modify and find new technique to granulate the powder. Among the new granulation technique are steam granulation, melt granulation, moisture activated dry granulation, foam granulation, pneumatic dry granulation technology and thermal adhesion granulation. Choosing a technique depends on the knowledge of advantages and disadvantages of each technique and how appropriate it is to the characteristics of each ingredient. This review mainly focusses on new techniques in granulation technologies for granules production. [ABSTRACT FROM AUTHOR]

In the present study, we prepared the gold nanoparticles (AgNPs) and chitosan/gold nanocomposites (CAgNPs) with a slight modification of the Turkevich method. The prepared AgNPs and CAgNPs were characters by UV-Vis, IR spectroscopy and Zetasizer. We found that the prepared AgNPs and CAgNPs have max of 246 nm and 251 nm, respectively. IR spectroscopic studies revealed that the chitosan was present in the prepared CAgNPs. The zeta potential of AgNPs and CAgNPs sol was found to be -45 and -46 in the sodium citrate solution. Moreover, the size of AgNPs was found to be 20 nm with 0.694 polydispersity index and the size of CAgNPs was 46 nm with a polydispersity index of 0.432, respectively. Based on these results we conclude that, chitosan was deposited on the surfaces of CAgNPs and the size was increased when compared with AgNPs and the CAgNPs sol color was changed to violet whereas AgNPs was red colour due to shifting in the max. [ABSTRACT FROM AUTHOR]