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Your search keyword '"Jung, Myeong Hee"' showing total 32 results
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32 results on '"Jung, Myeong Hee"'

4. Serum microRNA-185 Levels and Myocardial Injury in Patients with Acute ST-segment Elevation Myocardial Infarction

Author

Park, Jeong Rang, primary, Ahn, Jong Hwa, additional, Jung, Myeong Hee, additional, Kim, Jin Hyun, additional, Kang, Min Gyu, additional, Kim, Kye Hwan, additional, Jang, Jeong Yoon, additional, Park, Hyun Woong, additional, Koh, Jin-Sin, additional, Hwang, Seok-Jae, additional, Park, Yongwhi, additional, Jeong, Young-Hoon, additional, Kwak, Choong Hwan, additional, and Hwang, Jin-Yong, additional

Published
2022
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6. Supplementary_figure_1 – Supplemental material for The protective effect of human adiposederived mesenchymal stem cells on cisplatin-induced nephrotoxicity is dependent on their level of expression of heme oxygenase-1

Author

Cho, Hyun Seop, Jang, Ha Nee, Jung, Myeong Hee, Jang, Si Jung, Jeong, Sang-Ho, Lee, Tae Won, Eunjin Bae, Se-Ho Chang, Park, Dong Jun, and Kim, Jin Hyun

Subjects
110203 Respiratory Diseases, 70706 Veterinary Medicine, FOS: Clinical medicine, FOS: Veterinary sciences, Cell Biology, FOS: Health sciences, Biochemistry, FOS: Biological sciences, Medicine, 110309 Infectious Diseases, 111702 Aged Health Care, 111403 Paediatrics, 111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified, 69999 Biological Sciences not elsewhere classified
Abstract

Supplemental material, Supplementary_figure_1 for The protective effect of human adiposederived mesenchymal stem cells on cisplatin-induced nephrotoxicity is dependent on their level of expression of heme oxygenase-1 by Hyun Seop Cho, Ha Nee Jang, Myeong Hee Jung, Si Jung Jang, Sang-Ho Jeong, Tae Won Lee, Eunjin Bae, Se-Ho Chang, Dong Jun Park and Jin Hyun Kim in European Journal of Inflammation

Published
2020
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13. Therapeutic Effects of Intranasal Tofacitinib on Chronic Rhinosinusitis with Nasal Polyps in Mice.

Author

Joo, Yeon‐Hee, Cho, Hyun‐Jin, Jeon, Yung Jin, Kim, Jin Hyun, Jung, Myeong Hee, Jeon, Sea‐Yuong, Suh, Young Sun, Park, Jung Je, and Kim, Sang‐Wook

Abstract

Objectives: The Janus kinase/signal transducer and activator of transcription (JAK–STAT) pathway play a key role in immune modulation, especially in the polarization of T helper cells. JAK inhibitors reduce inflammation by inhibiting the phosphorylation of STAT. We investigated whether a JAK inhibitor, tofacitinib, can reduce inflammation in a mouse model of chronic rhinosinusitis with nasal polyps (CRSwNP). Methods: An eosinophilic CRSwNP model was induced using 4‐week‐old BALB/c mice. The therapeutic effects of topical tofacitinib were compared with the effects of triamcinolone acetonide (TAC). Polyp formation and eosinophilic infiltration were assessed by histology. Levels of phosphorylated STAT (pSTAT), eosinophil cationic protein, and eotaxin were measured by immunohistochemistry. Gene expression levels of GATA‐3 was measured using quantitative PCR. The production of cytokines in sinonasal tissues, including interleukin IL‐4, IL‐5, IL‐12, and interferon‐γ, were measured using enzyme‐linked immunosorbent assays (ELISA). Results: Topical tofacitinib administration significantly reduced the number of polyp‐like lesions and the degree of eosinophilic infiltration, with an efficacy comparable with that of systemic TAC administration. Similarly, the levels of pSTAT6, eosinophil cationic protein, and eotaxin decreased with tofacitinib treatment. Tofacitinib decreased the gene expression level of GATA‐3. Lastly, tofacitinib significantly decreased IL‐4 and IL‐5 production to a similar extent as that by systemic or topical TAC administration. Tofacitinib, but not TAC, significantly increased the production of interferon‐γ. Conclusion: Topical tofacitinib administration may be an effective treatment for eosinophilic CRSwNP by inhibiting phosphorylation of STATs. Level of Evidence: N/A. Laryngoscope, 131:E1400–E1407, 2021 [ABSTRACT FROM AUTHOR]

Published
2021
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28. Effects of Peroxisome Proliferator-Activated Receptor-δ Agonist on Cardiac Healing after Myocardial Infarction

Author

Park, Jeong Rang, primary, Ahn, Jong Hwa, additional, Jung, Myeong Hee, additional, Koh, Jin-Sin, additional, Park, Yongwhi, additional, Hwang, Seok-Jae, additional, Jeong, Young-Hoon, additional, Kwak, Choong Hwan, additional, Lee, Young Soo, additional, Seo, Han Geuk, additional, Kim, Jin Hyun, additional, and Hwang, Jin-Yong, additional

Published
2016
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