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1. Tracheal intubation in critically ill adults with a physiologically difficult airway. An international Delphi study

Author

Karamchandani, Kunal, Nasa, Prashant, Jarzebowski, Mary, Brewster, David J., De Jong, Audrey, Bauer, Philippe R., Berkow, Lauren, Brown, III, Calvin A., Cabrini, Luca, Casey, Jonathan, Cook, Tim, Divatia, Jigeeshu Vasishtha, Duggan, Laura V., Ellard, Louise, Ergan, Begum, Jonsson Fagerlund, Malin, Gatward, Jonathan, Greif, Robert, Higgs, Andy, Jaber, Samir, Janz, David, Joffe, Aaron M., Jung, Boris, Kovacs, George, Kwizera, Arthur, Laffey, John G., Lascarrou, Jean-Baptiste, Law, J. Adam, Marshall, Stuart, McGrath, Brendan A., Mosier, Jarrod M., Perin, Daniel, Roca, Oriol, Rollé, Amélie, Russotto, Vincenzo, Sakles, John C., Shrestha, Gentle S., Smischney, Nathan J., Sorbello, Massimiliano, Tung, Avery, Jabaley, Craig S., and Myatra, Sheila Nainan

Published
2024
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6. Effect of non-invasive ventilation after extubation in critically ill patients with obesity in France: a multicentre, unblinded, pragmatic randomised clinical trial

Author

DE JONG, AUDREY, BIGNON, ANNE, STEPHAN, FRANÇOIS, GODET, THOMAS, CONSTANTIN, JEAN-MICHEL, ASEHNOUNE, KARIM, SYLVESTRE, AUDE, SAUTILLET, JULIETTE, BLONDONNET, RAIKO, FERRANDIERE, MARTINE, SEGUIN, PHILIPPE, LASOCKI, SIGISMOND, ROLLE, AMELIE, FAYOLLE, PIERRE-MARIE, MULLER, LAURENT, PARDO, EMMANUEL, TERZI, NICOLAS, RAMIN, SEVERIN, JUNG, BORIS, ABBACK, PAER-SELIM, GUERCI, PHILIPPE, SARTON, BENJAMINE, ROZE, HADRIEN, DUPUIS, CLAIRE, COUSSON, JOEL, FAUCHER, MARION, LEMIALE, VIRGINIE, CHOLLEY, BERNARD, CHANQUES, GERALD, BELAFIA, FOUAD, HUGUET, HELENA, FUTIER, EMMANUEL, GNIADEK, CLAUDINE, VONARB, AURELIE, PRADES, ALBERT, JAILLET, CARINE, CAPDEVILA, XAVIER, CHARBIT, JONATHAN, GENTY, THIBAUT, REZAIGUIA-DELCLAUX, SAIDA, IMBERT, AUDREY, PILORGE, CATHERINE, CALYPSO, ROMAN, BOUTEAU-DURAND, ASTRID, CARLES, MICHEL, MEHDAOUI, HOSSEN, SOUWEINE, BERTRAND, CALVET, LAURE, JABAUDON, MATTHIEU, RIEU, BENJAMIN, CANDILLE, CLARA, SIGAUD, FLORIAN, RIU, BEATRICE, PAPAZIAN, LAURENT, VALERA, SABINE, MOKART, DJAMEL, CHOW CHINE, LAURENT, BISBAL, MAGALI, POULIQUEN, CAMILLE, DE GUIBERT, JEAN-MANUEL, TOURRET, MAXIME, MALLET, DAMIEN, LEONE, MARC, ZIELESKIEWICZ, LAURENT, COSSIC, JEANNE, ASSEFI, MONA, BARON, ELODIE, QUEMENEUR, CYRIL, MONSEL, ANTOINE, BIAIS, MATTHIEU, OUATTARA, ALEXANDRE, BONNARDEL, ELINE, MONZIOLS, SIMON, MAHUL, MARTIN, LEFRANT, JEAN-YVES, ROGER, CLAIRE, BARBAR, SABER, LAMBIOTTE, FABIEN, SAINT-LEGER, PIEHR, PAUGAM, CATHERINE, POTTECHER, JULIEN, LUDES, PIERRE-OLIVIER, DARRIVERE, LUCIE, GARNIER, MARC, KIPNIS, ERIC, LEBUFFE, GILLES, GAROT, MATTHIAS, FALCONE, JEREMY, CHOUSTERMAN, BENJAMIN, COLLET, MAGALI, GAYAT, ETIENNE, DELLAMONICA, JEAN, MFAM, WILLY-SERGE, OCHIN, EVELINA, NEBLI, MOHAMED, TILOUCHE, NEJLA, MADEUX, BENJAMIN, BOUGON, DAVID, AARAB, YASSIR, GARNIER, FANNY, AZOULAY, ELIE, MOLINARI, NICOLAS, JABER, SAMIR, De Jong, Audrey, Bignon, Anne, Stephan, François, Godet, Thomas, Constantin, Jean-Michel, Asehnoune, Karim, Sylvestre, Aude, Sautillet, Juliette, Blondonnet, Raiko, Ferrandière, Martine, Seguin, Philippe, Lasocki, Sigismond, Rollé, Amélie, Fayolle, Pierre-Marie, Muller, Laurent, Pardo, Emmanuel, Terzi, Nicolas, Ramin, Séverin, Jung, Boris, Abback, Paer-Selim, Guerci, Philippe, Sarton, Benjamine, Rozé, Hadrien, Dupuis, Claire, Cousson, Joel, Faucher, Marion, Lemiale, Virginie, Cholley, Bernard, Chanques, Gerald, Belafia, Fouad, Huguet, Helena, Futier, Emmanuel, Azoulay, Elie, Molinari, Nicolas, and Jaber, Samir

Published
2023
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8. Prognostic value of an automated thrombin generation assay in COVID-19 patients entering hospital: A multicentric, prospective observational study

Author

Gris, Jean-Christophe, Guillotin, Florence, dos Santos, Taissa Pereira, Chéa, Mathias, Loubet, Paul, Laureillard, Didier, Sotto, Albert, Muller, Laurent, Barbar, Saber Davide, Roger, Claire, Lefrant, Jean-Yves, Jung, Boris, Klouche, Kada, Mura, Thibault, Quéré, Isabelle, and Perez-Martin, Antonia

Published
2023
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12. Adjustments of Ventilator Parameters during Operating Room–to–ICU Transition and 28-Day Mortality

Author

von Wedel, Dario, primary, Redaelli, Simone, additional, Suleiman, Aiman, additional, Wachtendorf, Luca J., additional, Fosset, Maxime, additional, Santer, Peter, additional, Shay, Denys, additional, Munoz-Acuna, Ricardo, additional, Chen, Guanqing, additional, Talmor, Daniel, additional, Jung, Boris, additional, Baedorf-Kassis, Elias N., additional, and Schaefer, Maximilian S., additional

Published
2024
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13. Diaphragm Involvement

Author

Jung, Boris, Matecki, Stefan, Jaber, Samir, Cecconi, Maurizio, Series Editor, De Backer, Daniel, Series Editor, Preiser, Jean-Charles, editor, Herridge, Margaret, editor, and Azoulay, Elie, editor

Published
2020
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15. Early and late effects of volatile sedation with sevoflurane on respiratory mechanics of critically ill COPD patients.

Author

Jung, Boris, Fosset, Maxime, Amalric, Matthieu, Baedorf-Kassis, Elias, O'Gara, Brian, Sarge, Todd, Moulaire, Valerie, Brunot, Vincent, Bourdin, Arnaud, Molinari, Nicolas, and Matecki, Stefan

Subjects
*OBSTRUCTIVE lung disease treatment, *BLOOD gases analysis, *SEVOFLURANE, *RESEARCH funding, *CRITICALLY ill, *PATIENTS, *ACADEMIC medical centers, *POSITIVE end-expiratory pressure, *INHALATION anesthesia, *STATISTICAL sampling, *TREATMENT effectiveness, *RANDOMIZED controlled trials, *DESCRIPTIVE statistics, *PROPOFOL, *ARTIFICIAL respiration, *INTRAVENOUS anesthesia, *RESPIRATORY measurements, *AIRWAY (Anatomy), *RESPIRATORY mechanics, *CRITICAL care medicine
Abstract

Background: The objective was to compare sevoflurane, a volatile sedation agent with potential bronchodilatory properties, with propofol on respiratory mechanics in critically ill patients with COPD exacerbation. Methods: Prospective study in an ICU enrolling critically ill intubated patients with severe COPD exacerbation and comparing propofol and sevoflurane after 1:1 randomisation. Respiratory system mechanics (airway resistance, PEEPi, trapped volume, ventilatory ratio and respiratory system compliance), gas exchange, vitals, safety and outcome were measured at inclusion and then until H48. Total airway resistance change from baseline to H48 in both sevoflurane and propofol groups was the main endpoint. Results: Sixteen patients were enrolled and were sedated for 126 h(61–228) in the propofol group and 207 h(171–216) in the sevoflurane group. At baseline, airway resistance was 21.6cmH2O/l/s(19.8–21.6) in the propofol group and 20.4cmH2O/l/s(18.6–26.4) in the sevoflurane group, (p = 0.73); trapped volume was 260 ml(176–290) in the propofol group and 73 ml(35–126) in the sevoflurane group, p = 0.02. Intrinsic PEEP was 1.5cmH2O(1–3) in both groups after external PEEP optimization. There was neither early (H4) or late (H48) significant difference in airway resistance and respiratory mechanics parameters between the two groups. Conclusions: In critically ill patients intubated with COPD exacerbation, there was no significant difference in respiratory mechanics between sevoflurane and propofol from inclusion to H4 and H48. [ABSTRACT FROM AUTHOR]

Published
2024
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16. Inadequate intensive care physician supply in France: a point-prevalence prospective study.

Author

Sarfati, Sacha, Ehrmann, Stephan, Vodovar, Dominique, Jung, Boris, Aissaoui, Nadia, Darreau, Cédric, Bougouin, Wulfran, Deye, Nicolas, Kallel, Hatem, Kuteifan, Khaldoun, Luyt, Charles-Edouard, Terzi, Nicolas, Vanderlinden, Thierry, Vinsonneau, Christophe, Muller, Grégoire, and Guitton, Christophe

Subjects
HOSPITAL utilization, PUBLIC hospitals, ACADEMIC medical centers, QUALITATIVE research, RETIREMENT, QUESTIONNAIRES, DISEASE prevalence, DESCRIPTIVE statistics, LONGITUDINAL method, SURVEYS, WORKING hours, INTENSIVE care units, LABOR demand, EMPLOYEE recruitment, PHYSICIANS, COMPARATIVE studies, LABOR supply, SHIFT systems
Abstract

Background: The COVID-19 pandemic has highlighted the importance of intensive care units (ICUs) and their organization in healthcare systems. However, ICU capacity and availability are ongoing concerns beyond the pandemic, particularly due to an aging population and increasing complexity of care. This study aimed to assess the current and future shortage of ICU physicians in France, ten years after a previous evaluation. A national e-survey was conducted among French ICUs in January 2022 to collect data on ICU characteristics, medical staffing, individual physician characteristics, and education and training capacities. Results: Among 290 ICUs contacted, 242 responded (response rate: 83%), representing 4943 ICU beds. The survey revealed an overall of 300 full time equivalent (FTE) ICU physician vacancies in the country. Nearly two-thirds of the participating ICUs reported at least one physician vacancy and 35% relied on traveling physicians to cover shifts. The ICUs most affected by physician vacancies were the ICUs of non-university affiliated public hospitals. The retirements expected in the next five years represented around 10% of the workforce. The median number of physicians per ICU was 7.0, corresponding to a ratio of 0.36 physician (FTE) per ICU bed. In addition, 27% of ICUs were at risk of critical dysfunction or closure due to vacancies and impending retirements. Conclusion: The findings highlight the urgent need to address the shortage of ICU physicians in France. Compared to a similar study conducted in 2012, the inadequacy between ICU physician supply and demand has increased, resulting in a higher number of vacancies. Our study suggests that, among others, increasing the number of ICM residents trained each year could be a crucial step in addressing this issue. Failure to take appropriate measures may lead to further closures of ICUs and increased risks to patients in this healthcare system. [ABSTRACT FROM AUTHOR]

Published
2024
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18. Le métabolisme énergétique au cours des états critiques : actes du 8ème Séminaire de Recherche Translationnelle de la Société de Réanimation de Langue Française (Paris, 2 décembre 2022)

Author

De la SRLF, CRT, primary, Radermacher, Peter, additional, Oualha, Mehdi, additional, Stiel, Laure, additional, Vandewalle, Jolien, additional, Jouan, Youenn, additional, Fontaine, Eric, additional, Joffre, Jeremie, additional, Kreitmann, Louis, additional, Benghanem, Sarah, additional, Jung, Boris, additional, Schiff, Manuel, additional, Gaudet, Alexandre, additional, Pickkers, Peter, additional, Sarton, Benjamine, additional, Berger, Mette, additional, Merz, Tamara, additional, Kallel, Hatem, additional, Bréchot, Nicolas, additional, Voiriot, Guillaume, additional, and Préau, Sébastien, additional

Published
2023
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20. Energetic dysfunction in sepsis: a narrative review

Author

Preau, Sebastien, Vodovar, Dominique, Jung, Boris, Lancel, Steve, Zafrani, Lara, Flatres, Aurelien, Oualha, Mehdi, Voiriot, Guillaume, Jouan, Youenn, Joffre, Jeremie, Uhel, Fabrice, De Prost, Nicolas, Silva, Stein, Azabou, Eric, and Radermacher, Peter

Published
2021
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27. Pneumonies associées aux soins de réanimation

Author

Leone, Marc, Bouadma, Lila, Bouhemad, Belaïd, Brissaud, Olivier, Dauger, Stéphane, Gibot, Sébastien, Hraiech, Sami, Jung, Boris, Kipnis, Eric, Launey, Yoann, Luyt, Charles-Edouard, Margetis, Dimitri, Michel, Fabrice, Mokart, Djamel, Montravers, Philippe, Monsel, Antoine, Nseir, Saad, Pugin, Jérôme, Roquilly, Antoine, Velly, Lionel, Zahar, Jean-Ralph, Bruyère, Rémi, and Chanques, Gérald

Published
2018
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28. Hospital-acquired pneumonia in ICU

Author

Leone, Marc, Bouadma, Lila, Bouhemad, Bélaïd, Brissaud, Olivier, Dauger, Stéphane, Gibot, Sébastien, Hraiech, Sami, Jung, Boris, Kipnis, Eric, Launey, Yoann, Luyt, Charles-Edouard, Margetis, Dimitri, Michel, Fabrice, Mokart, Djamel, Montravers, Philippe, Monsel, Antoine, Nseir, Saad, Pugin, Jérôme, Roquilly, Antoine, Velly, Lionel, Zahar, Jean-Ralph, Bruyère, Rémi, and Chanques, Gérald

Published
2018
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30. Immediate interruption of sedation compared with usual sedation care in critically ill postoperative patients (SOS-Ventilation): a randomised, parallel-group clinical trial

Author

Chanques, Gerald, Conseil, Matthieu, Prades, Albert, Carr, Julie, Jung, Boris, Belafia, Fouad, Cissé, Moussa, Delay, Jean-Marc, De Jong, Audrey, Verzilli, Daniel, Clavieras, Noémie, Jaber, Samir, Mercier, Grégoire, Molinari, Nicolas, Mathieu, Emmanuelle, Bertet, Héléna, Roger, Claire, Muller, Laurent, Lefrant, Jean-Yves, Boutin, Caroline, Constantin, Jean-Michel, Futier, Emmanuel, Cayot, Sophie, Perbet, Sébastien, Jabaudon, Matthieu, and de Jong, Audrey

Published
2017
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32. Mechanical power and 30-day mortality in mechanically ventilated, critically ill patients with and without Coronavirus Disease-2019: a hospital registry study

Author

Azizi, B, Munoz-Acuna, R, Suleiman, A, Ahrens, E, Redaelli, S, Tartler, T, Chen, G, Jung, B, Talmor, D, Baedorf-Kassis, E, Schaefer, M, Azizi, Basit A, Munoz-Acuna, Ricardo, Suleiman, Aiman, Ahrens, Elena, Redaelli, Simone, Tartler, Tim M, Chen, Guanqing, Jung, Boris, Talmor, Daniel, Baedorf-Kassis, Elias N, Schaefer, Maximilian S, Azizi, B, Munoz-Acuna, R, Suleiman, A, Ahrens, E, Redaelli, S, Tartler, T, Chen, G, Jung, B, Talmor, D, Baedorf-Kassis, E, Schaefer, M, Azizi, Basit A, Munoz-Acuna, Ricardo, Suleiman, Aiman, Ahrens, Elena, Redaelli, Simone, Tartler, Tim M, Chen, Guanqing, Jung, Boris, Talmor, Daniel, Baedorf-Kassis, Elias N, and Schaefer, Maximilian S

Abstract

BackgroundPrevious studies linked a high intensity of ventilation, measured as mechanical power, to mortality in patients suffering from "classic" ARDS. By contrast, mechanically ventilated patients with a diagnosis of COVID-19 may present with intact pulmonary mechanics while undergoing mechanical ventilation for longer periods of time. We investigated whether an association between higher mechanical power and mortality is modified by a diagnosis of COVID-19.MethodsThis retrospective study included critically ill, adult patients who were mechanically ventilated for at least 24 h between March 2020 and December 2021 at a tertiary healthcare facility in Boston, Massachusetts. The primary exposure was median mechanical power during the first 24 h of mechanical ventilation, calculated using a previously validated formula. The primary outcome was 30-day mortality. As co-primary analysis, we investigated whether a diagnosis of COVID-19 modified the primary association. We further investigated the association between mechanical power and days being alive and ventilator free and effect modification of this by a diagnosis of COVID-19. Multivariable logistic regression, effect modification and negative binomial regression analyses adjusted for baseline patient characteristics, severity of disease and in-hospital factors, were applied.Results1,737 mechanically ventilated patients were included, 411 (23.7%) suffered from COVID-19. 509 (29.3%) died within 30 days. The median mechanical power during the first 24 h of ventilation was 19.3 [14.6-24.0] J/min in patients with and 13.2 [10.2-18.0] J/min in patients without COVID-19. A higher mechanical power was associated with 30-day mortality (ORadj 1.26 per 1-SD, 7.1J/min increase; 95% CI 1.09-1.46; p = 0.002). Effect modification and interaction analysis did not support that this association was modified by a diagnosis of COVID-19 (95% CI, 0.81-1.38; p-for-interaction = 0.68). A higher mechanical power was associated with a lower

Published
2023

36. Management of severe asthma exacerbation: guidelines from the Société Française de Médecine d’Urgence, the Société de Réanimation de Langue Française and the French Group for Pediatric Intensive Care and Emergencies

Author

Le Conte, Philippe, Terzi, Nicolas, Mortamet, Guillaume, Abroug, Fekri, Carteaux, Guillaume, Charasse, Céline, Chauvin, Anthony, Combes, Xavier, Dauger, Stéphane, Demoule, Alexandre, Desmettre, Thibaut, Ehrmann, Stephan, Gaillard-Le Roux, Bénédicte, Hamel, Valérie, Jung, Boris, Kepka, Sabrina, L’Her, Erwan, Martinez, Mikaël, Milési, Christophe, Morawiec, Élise, Oberlin, Mathieu, Plaisance, Patrick, Pouyau, Robin, Raherison, Chantal, Ray, Patrick, Schmidt, Mathieu, Thille, Arnaud W., Truchot, Jennifer, Valdenaire, Guillaume, Vaux, Julien, Viglino, Damien, Voiriot, Guillaume, Vrignaud, Bénédicte, Jean, Sandrine, Mariotte, Eric, and Claret, Pierre-Géraud

Published
2019
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39. Sodium flux during hemodialysis and hemodiafiltration treatment of acute kidney injury: Effects of dialysate and infusate sodium concentration at 140 and 145 mmol/L

Author

Buzancais, Aurèle, primary, Brunot, Vincent, additional, Larcher, Romaric, additional, Tudesq, Jean‐Jacques, additional, Platon, Laura, additional, Besnard, Noémie, additional, Amalric, Matthieu, additional, Daubin, Delphine, additional, Corne, Philippe, additional, Moulaire, Valérie, additional, Jung, Boris, additional, Canaud, Bernard, additional, Cristol, Jean‐Paul, additional, and Klouche, Kada, additional

Published
2023
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41. Additional file 1 of Mechanical power and 30-day mortality in mechanically ventilated, critically ill patients with and without Coronavirus Disease-2019: a hospital registry study

Author

Azizi, Basit A., Munoz-Acuna, Ricardo, Suleiman, Aiman, Ahrens, Elena, Redaelli, Simone, Tartler, Tim M., Chen, Guanqing, Jung, Boris, Talmor, Daniel, Baedorf-Kassis, Elias N., and Schaefer, Maximilian S.

Abstract

Additional file 1. Additional details on methods and results.

Published
2023
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42. Diagnosis and management of metabolic acidosis: guidelines from a French expert panel

Author

Jung, Boris, Martinez, Mikaël, Claessens, Yann-Erick, Darmon, Michaël, Klouche, Kada, Lautrette, Alexandre, Levraut, Jacques, Maury, Eric, Oberlin, Mathieu, Terzi, Nicolas, Viglino, Damien, Yordanov, Youri, Claret, Pierre-Géraud, Bigé, Naïke, for the Société de Réanimation de Langue Française (SRLF), and the Société Française de Médecine d’Urgence (SFMU)

Published
2019
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43. Preclinical septic shock research: why we need an animal ICU

Author

Guillon, Antoine, Preau, Sebastien, Aboab, Jérôme, Azabou, Eric, Jung, Boris, Silva, Stein, Textoris, Julien, Uhel, Fabrice, Vodovar, Dominique, Zafrani, Lara, de Prost, Nicolas, Radermacher, Peter, and Translational Research Committee of the French Intensive Care Society (Société de Réanimation de Langue Française)

Published
2019
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44. Update in Neurocritical Care: a summary of the 2018 Paris international conference of the French Society of Intensive Care

Author

Oddo, Mauro, Bracard, Serge, Cariou, Alain, Chanques, Gérald, Citerio, Giuseppe, Clerckx, Béatrix, Godeau, Bertrand, Godier, Anne, Horn, Janneke, Jaber, Samir, Jung, Boris, Kuteifan, Khaldoun, Leone, Marc, Mailles, Alexandra, Mazighi, Mikael, Mégarbane, Bruno, Outin, Hervé, Puybasset, Louis, Sharshar, Tarek, Sandroni, Claudio, Sonneville, Romain, Weiss, Nicolas, and Taccone, Fabio Silvio

Published
2019
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45. Brief summary of French guidelines for the prevention, diagnosis and treatment of hospital-acquired pneumonia in ICU

Author

Leone, Marc, Bouadma, Lila, Bouhemad, Bélaïd, Brissaud, Olivier, Dauger, Stéphane, Gibot, Sébastien, Hraiech, Sami, Jung, Boris, Kipnis, Eric, Launey, Yoann, Luyt, Charles-Edouard, Margetis, Dimitri, Michel, Fabrice, Mokart, Djamel, Montravers, Philippe, Monsel, Antoine, Nseir, Saad, Pugin, Jérôme, Roquilly, Antoine, Velly, Lionel, Zahar, Jean-Ralph, Bruyère, Rémi, Chanques, Gérald, ADARPEF, and GFRUP

Published
2018
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50. PLATO Fast Front End Electronics (F-FEE) - performance results of the engineering model

Author

Koncz, Alexander, Eigmüller, Philipp, Michaelis, Harald, Rauer, Heike, Wolter, David, Tschentscher, Matthias, Weisse, Stefan, Vasiliou, Konstantinos, Tomecki, Daniel, Rufini, Sergio, Cacovean, Andrei, Althaus, Christian, Jung, Boris, Müller, Uwe, Korsitzky, Hartmut, Terzer, Ronny, Manthey, Kristian, Grott, Matthias, Ligus, Jan, Hviid, Stubbe, Cara, Christophe, Lavanant, Tony, Fontignie, Jean, Huynh, Dat, Nico, Francois, and Niemi, Sami

Subjects
Fast telescope, CEA, DLR, Fine Guidance, Charged-coupled devices, CCD Cameras, Electronics, PLATO, ESA, Front-end, CCD
Published
2022

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