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330 results on '"Jong, Koert P."'

1. Prognostic value of total tumor volume in patients with colorectal liver metastases: A secondary analysis of the randomized CAIRO5 trial with external cohort validation

Author

Michiel Zeeuw, J., Wesdorp, Nina J., Ali, Mahsoem, Bakker, Anne-Joëlle J.J., Voigt, Kelly R., Starmans, Martijn P.A., Roor, Joran, Kemna, Ruby, van Waesberghe, Jan Hein T.M., van den Bergh, Janneke E., Nota, Irene M.G.C., Moos, Shira I., van Dieren, Susan, van Amerongen, Martinus J., Bond, Marinde J.G., Chapelle, Thiery, van Dam, Ronald M., Engelbrecht, Marc R.W., Gerhards, Michael F., van Gulik, Thomas M., Hermans, John J., de Jong, Koert P., Klaase, Joost M., Kok, Niels F.M., Leclercq, Wouter K.G., Liem, Mike S.L., van Lienden, Krijn P., Quintus Molenaar, I., Patijn, Gijs A., Rijken, Arjen M., Ruers, Theo M., de Wilt, Johannes H.W., Verpalen, Inez M., Stoker, Jaap, Grunhagen, Dirk J., Swijnenburg, Rutger-Jan, Punt, Cornelis J.A., Huiskens, Joost, Verhoef, Cornelis, and Kazemier, Geert

Published
2024
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2. Deep learning models for automatic tumor segmentation and total tumor volume assessment in patients with colorectal liver metastases

Author

Wesdorp, Nina J., Zeeuw, J. Michiel, Postma, Sam C. J., Roor, Joran, van Waesberghe, Jan Hein T. M., van den Bergh, Janneke E., Nota, Irene M., Moos, Shira, Kemna, Ruby, Vadakkumpadan, Fijoy, Ambrozic, Courtney, van Dieren, Susan, van Amerongen, Martinus J., Chapelle, Thiery, Engelbrecht, Marc R. W., Gerhards, Michael F., Grunhagen, Dirk, van Gulik, Thomas M., Hermans, John J., de Jong, Koert P., Klaase, Joost M., Liem, Mike S. L., van Lienden, Krijn P., Molenaar, I. Quintus, Patijn, Gijs A., Rijken, Arjen M., Ruers, Theo M., Verhoef, Cornelis, de Wilt, Johannes H. W., Marquering, Henk A., Stoker, Jaap, Swijnenburg, Rutger-Jan, Punt, Cornelis J. A., Huiskens, Joost, and Kazemier, Geert

Published
2023
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4. Intersurgeon Variability in Local Treatment Planning for Patients with Initially Unresectable Colorectal Cancer Liver Metastases: Analysis of the Liver Expert Panel of the Dutch Colorectal Cancer Group

Author

Bond, Marinde J. G., Kuiper, Babette I., Bolhuis, Karen, Komurcu, Aysun, van Amerongen, Martinus J., Chapelle, Thiery, Dejong, Cornelis H. C., Engelbrecht, Marc R. W., Gerhards, Michael F., Grünhagen, Dirk J., van Gulik, Thomas, Hermans, John J., de Jong, Koert P., Klaase, Joost M., Kok, Niels F. M., Leclercq, Wouter K. G., Liem, Mike S. L., van Lienden, Krijn P., Molenaar, I. Quintus, Neumann, Ulf P., Patijn, Gijs A., Rijken, Arjen M., Ruers, Theo M., Verhoef, Cornelis, de Wilt, Johannes H. W., Kazemier, Geert, May, Anne M., Punt, Cornelis J. A., and Swijnenburg, Rutger-Jan

Published
2023
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6. First-line systemic treatment strategies in patients with initially unresectable colorectal cancer liver metastases (CAIRO5): an open-label, multicentre, randomised, controlled, phase 3 study from the Dutch Colorectal Cancer Group

Author

Van Gulik, Thomas, Huiskens, Joost, Van Tinteren, Harm, Dejong, Cornelis H.C., Grünhagen, Dirk J., Patijn, Gijs A., Ruers, Theo J.M., Chapelle, Thiery, Hermans, John J., Leclercq, Wouter K.G., Valkenburg-van Iersel, Liselot B.J., Grootscholten, Cecile, Van Dodewaard-de Jong, Joyce M., Vincent, Jeroen, Houtsma, Danny, Los, Maartje, Den Boer, Marien, Trajkovic-Vidakovic, Marija, Van Voorthuizen, Theo, Koopman, Miriam, Vestjens, Johanneke H.M.J.V., Torrenga, Hans, Mekenkamp, Leonie J., Veldhuis, Gerrit Jan, Polee, Marco B., Dohmen, Serge E., Schut, Heidi, Vulink, Annelie J.E., Van Halteren, Henk K., Oulad Hadj, Jamal, Schiphorst, Pieter-Paul J.B.M., Hoekstra, Ronald, Bond, Marinde J G, Bolhuis, Karen, Loosveld, Olaf J L, de Groot, Jan Willem B, Droogendijk, Helga, Helgason, Helgi H, Hendriks, Mathijs P, Klaase, Joost M, Kazemier, Geert, Liem, Mike S L, Rijken, Arjen M, Verhoef, Cornelis, de Wilt, Johannes H W, de Jong, Koert P, Gerhards, Michael F, van Amerongen, Martinus J, Engelbrecht, Marc R W, van Lienden, Krijn P, Molenaar, I Quintus, de Valk, Bart, Haberkorn, Brigitte C M, Kerver, Emile D, Erdkamp, Frans, van Alphen, Robbert J, Mathijssen-van Stein, Daniëlle, Komurcu, Aysun, Lopez-Yurda, Marta, Swijnenburg, Rutger-Jan, and Punt, Cornelis J A

Published
2023
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7. The role of tumour biological factors in technical anatomical resectability assessment of colorectal liver metastases following induction systemic treatment: An analysis of the Dutch CAIRO5 trial

Author

Bolhuis, Karen, Bond, Marinde J.G., Van Amerongen, Martin J., Komurcu, Aysun, Chapelle, Thiery, Dejong, Cornelis H.C., Engelbrecht, Marc R.W., Gerhards, Michael F., Grünhagen, Dirk J., van Gulik, Thomas M., Hermans, John J., De Jong, Koert P., Kazemier, Geert, Klaase, Joost M., Kok, Niels F.M., Leclercq, Wouter K.G., Liem, Mike S.L., van Lienden, Krijn P., Molenaar, I. Quintus, Neumann, Ulf P., Patijn, Gijs A., Rijken, Arjen M., Ruers, Theo M., Verhoef, Cornelis, de Wilt, Johannes H.W., May, Anne M., Punt, Cornelis J.A., and Swijnenburg, Rutger-Jan

Published
2023
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9. Study Protocol PROMETHEUS: Prospective Multicenter Study to Evaluate the Correlation Between Safety Margin and Local Recurrence After Thermal Ablation Using Image Co-registration in Patients with Hepatocellular Carcinoma

Author

Oosterveer, Timo T. M., van Erp, Gonnie C. M., Hendriks, Pim, Broersen, Alexander, Overduin, Christiaan G., van Rijswijk, Carla S. P., van Erkel, Arian R., van der Meer, Rutger W., Tushuizen, Maarten E., Moelker, Adriaan, Meijerink, Martijn R., van Delden, Otto M., de Jong, Koert P., van der Leij, Christiaan, Smits, Maarten L. J., Urlings, Thijs A. J., Braak, Jeffrey P. B. M., Meershoek-Klein Kranenbarg, Elma, van Duijn-de Vreugd, Bianca, Zeijdner, Evelijn, Goeman, Jelle J., Fütterer, Jurgen J., Coenraad, Minneke J., Dijkstra, Jouke, and Burgmans, Mark C.

Published
2022
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12. Pancreatic resection in the pediatric, adolescent and young adult population: nationwide analysis on complications

Author

Pranger, Bobby K., van Dam, Jacob L., Groen, Jesse V., van Eijck, Casper H., Koerkamp, Bas G., Bonsing, Bert A., Mieog, J.Sven D., Besselink, Marc G., Busch, Olivier R., Kazemier, Geert, de Jong, Koert P., de Kleine, Ruben H.J., Molenaar, I.Quintus, Stommel, Martijn W.J., Gerhards, Michael F., Coolsen, Marielle M.E., van Santvoort, Hjalmar C., van der Harst, Erwin, Klaase, Joost M., and de Meijer, Vincent E.

Published
2021
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13. Lessons learned from site-specific sampling and biological half-life of IGFII and IIE(68-88) peptide: A case study

Author

Other research (not in main researchprogram), CDL Cluster Speciële Diagnostiek, Muller Kobold, Anneke C., De Haan, Jacco J., Bokkers, Reinoud P.H., Ruiter, Simeon J.S., Van Den Heuvel, Marius C., Lentjes, Eef G.W.M., Touw, Daan J., De Jong, Koert P., Other research (not in main researchprogram), CDL Cluster Speciële Diagnostiek, Muller Kobold, Anneke C., De Haan, Jacco J., Bokkers, Reinoud P.H., Ruiter, Simeon J.S., Van Den Heuvel, Marius C., Lentjes, Eef G.W.M., Touw, Daan J., and De Jong, Koert P.

Published
2024

14. Prognostic value of total tumor volume in patients with colorectal liver metastases: A secondary analysis of the randomized CAIRO5 trial with external cohort validation

Author

Hart- en Vaatziekten Team A, Epi Kanker Team B, Cancer, MS CGO, Zorgeenheid Kinderchirurgie Medisch, Researchgr. Beeldg. Moleculaire Interv., Michiel Zeeuw, J., Wesdorp, Nina J., Ali, Mahsoem, Bakker, Anne Joëlle J.J., Voigt, Kelly R., Starmans, Martijn P.A., Roor, Joran, Kemna, Ruby, van Waesberghe, Jan Hein T.M., van den Bergh, Janneke E., Nota, Irene M.G.C., Moos, Shira I., van Dieren, Susan, van Amerongen, Martinus J., Bond, Marinde J.G., Chapelle, Thiery, van Dam, Ronald M., Engelbrecht, Marc R.W., Gerhards, Michael F., van Gulik, Thomas M., Hermans, John J., de Jong, Koert P., Klaase, Joost M., Kok, Niels F.M., Leclercq, Wouter K.G., Liem, Mike S.L., van Lienden, Krijn P., Quintus Molenaar, I., Patijn, Gijs A., Rijken, Arjen M., Ruers, Theo M., de Wilt, Johannes H.W., Verpalen, Inez M., Stoker, Jaap, Grunhagen, Dirk J., Swijnenburg, Rutger Jan, Punt, Cornelis J.A., Huiskens, Joost, Verhoef, Cornelis, Kazemier, Geert, Hart- en Vaatziekten Team A, Epi Kanker Team B, Cancer, MS CGO, Zorgeenheid Kinderchirurgie Medisch, Researchgr. Beeldg. Moleculaire Interv., Michiel Zeeuw, J., Wesdorp, Nina J., Ali, Mahsoem, Bakker, Anne Joëlle J.J., Voigt, Kelly R., Starmans, Martijn P.A., Roor, Joran, Kemna, Ruby, van Waesberghe, Jan Hein T.M., van den Bergh, Janneke E., Nota, Irene M.G.C., Moos, Shira I., van Dieren, Susan, van Amerongen, Martinus J., Bond, Marinde J.G., Chapelle, Thiery, van Dam, Ronald M., Engelbrecht, Marc R.W., Gerhards, Michael F., van Gulik, Thomas M., Hermans, John J., de Jong, Koert P., Klaase, Joost M., Kok, Niels F.M., Leclercq, Wouter K.G., Liem, Mike S.L., van Lienden, Krijn P., Quintus Molenaar, I., Patijn, Gijs A., Rijken, Arjen M., Ruers, Theo M., de Wilt, Johannes H.W., Verpalen, Inez M., Stoker, Jaap, Grunhagen, Dirk J., Swijnenburg, Rutger Jan, Punt, Cornelis J.A., Huiskens, Joost, Verhoef, Cornelis, and Kazemier, Geert

Published
2024

15. Prognostic value of total tumor volume in patients with colorectal liver metastases:A secondary analysis of the randomized CAIRO5 trial with external cohort validation

Author

Michiel Zeeuw, J., Wesdorp, Nina J., Ali, Mahsoem, Bakker, Anne Joëlle J.J., Voigt, Kelly R., Starmans, Martijn P.A., Roor, Joran, Kemna, Ruby, van Waesberghe, Jan Hein T.M., van den Bergh, Janneke E., Nota, Irene M.G.C., Moos, Shira I., van Dieren, Susan, van Amerongen, Martinus J., Bond, Marinde J.G., Chapelle, Thiery, van Dam, Ronald M., Engelbrecht, Marc R.W., Gerhards, Michael F., van Gulik, Thomas M., Hermans, John J., de Jong, Koert P., Klaase, Joost M., Kok, Niels F.M., Leclercq, Wouter K.G., Liem, Mike S.L., van Lienden, Krijn P., Quintus Molenaar, I., Patijn, Gijs A., Rijken, Arjen M., Ruers, Theo M., de Wilt, Johannes H.W., Verpalen, Inez M., Stoker, Jaap, Grunhagen, Dirk J., Swijnenburg, Rutger Jan, Punt, Cornelis J.A., Huiskens, Joost, Verhoef, Cornelis, Kazemier, Geert, Michiel Zeeuw, J., Wesdorp, Nina J., Ali, Mahsoem, Bakker, Anne Joëlle J.J., Voigt, Kelly R., Starmans, Martijn P.A., Roor, Joran, Kemna, Ruby, van Waesberghe, Jan Hein T.M., van den Bergh, Janneke E., Nota, Irene M.G.C., Moos, Shira I., van Dieren, Susan, van Amerongen, Martinus J., Bond, Marinde J.G., Chapelle, Thiery, van Dam, Ronald M., Engelbrecht, Marc R.W., Gerhards, Michael F., van Gulik, Thomas M., Hermans, John J., de Jong, Koert P., Klaase, Joost M., Kok, Niels F.M., Leclercq, Wouter K.G., Liem, Mike S.L., van Lienden, Krijn P., Quintus Molenaar, I., Patijn, Gijs A., Rijken, Arjen M., Ruers, Theo M., de Wilt, Johannes H.W., Verpalen, Inez M., Stoker, Jaap, Grunhagen, Dirk J., Swijnenburg, Rutger Jan, Punt, Cornelis J.A., Huiskens, Joost, Verhoef, Cornelis, and Kazemier, Geert

Abstract

Background:This study aimed to assess the prognostic value of total tumor volume (TTV) for early recurrence (within 6 months) and overall survival (OS) in patients with colorectal liver metastases (CRLM), treated with induction systemic therapy followed by complete local treatment.Methods: Patients with initially unresectable CRLM from the multicenter randomized phase 3 CAIRO5 trial (NCT02162563) who received induction systemic therapy followed by local treatment were included. Baseline TTV and change in TTV as response to systemic therapy were calculated using the CT scan before and the first after systemic treatment, and were assessed for their added prognostic value. The findings were validated in an external cohort of patients treated at a tertiary center. Results:In total, 215 CAIRO5 patients were included. Baseline TTV and absolute change in TTV were significantly associated with early recurrence (P = 0.005 and P = 0.040, respectively) and OS in multivariable analyses (P = 0.024 and P = 0.006, respectively), whereas RECIST1.1 was not prognostic for early recurrence (P = 0.88) and OS (P = 0.35). In the validation cohort (n = 85), baseline TTV and absolute change in TTV remained prognostic for early recurrence (P = 0.041 and P = 0.021, respectively) and OS in multivariable analyses (P < 0.0001 and P = 0.012, respectively), and showed added prognostic value over conventional clinicopathological variables (increase C-statistic, 0.06; 95 % CI, 0.02 to 0.14; P = 0.008). Conclusion: Total tumor volume is strongly prognostic for early recurrence and OS in patients who underwent complete local treatment of initially unresectable CRLM, both in the CAIRO5 trial and the validation cohort. In contrast, RECIST1.1 did not show prognostic value for neither early recurrence nor OS.

Published
2024

16. Lessons learned from site-specific sampling and biological half-life of IGFII and IIE(68-88) peptide: a case study.

Author

Muller Kobold, Anneke C., de Haan, Jacco J., Bokkers, Reinoud P.H., Ruiter, Simeon J.S., van den Heuvel, Marius C., Lentjes, Eef G.W.M., Touw, Daan J., and de Jong, Koert P.

Subjects
PEPTIDES, HEPATIC veins, RENAL veins, INSULIN-like growth factor-binding proteins, SOMATOMEDIN A
Abstract

This article presents a case study on non-islet cell tumor induced hypoglycemia (NICTH), a rare condition associated with mesenchymal tumors. The study focuses on a patient with metastatic solitary fibrous tumors (SFT) and severe hypoglycemic symptoms. The researchers measured levels of insulin-like growth factor (IGF)-II and IIE(68-88) peptide in various sampling sites, including the hepatic vein draining the largest SFT metastasis. They also measured these substances in peripheral venous blood samples taken at different timepoints after tumor resection to determine their half-life and correlate the levels with tumor size and clinical parameters. The findings provide insight into the contribution of liver metastases to hormone production and highlight the importance of site-specific sampling in understanding the metabolism of tumor cells. However, the study suggests that site-specific sampling may have limited value in identifying the dominant hormone-producing site in patients with SFT. [Extracted from the article]

Published
2024
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17. Outcomes of Resectability Assessment of the Dutch Colorectal Cancer Group Liver Metastases Expert Panel

Author

Van Amerongen, M.J., Dejong, Cornelis HC., Gerhards, Michael F., Grunhagen, Dirk, Heijmen, Linda, Hermans, John J., Keijser, Astrid, Klaase, Joost M., Van Lienden, Krijn P, Molenaar, Quintus I., Patijn, Gijs A., Rijken, Arjen M., Ruers, Theo M., Swijnenburg, Rutger-Jan, van Tinteren, Harm, Huiskens, Joost, Bolhuis, Karen, Engelbrecht, Marc RW., De Jong, Koert P., Kazemier, Geert, Liem, Mike SL., Verhoef, Cornelis, de Wilt, Johannes HW., Punt, Cornelis JA., and van Gulik, Thomas M.

Published
2019
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18. External Validity of the Multicenter Randomized PREOPANC Trial on Neoadjuvant Chemoradiotherapy in Pancreatic Cancer: Outcome of Eligible but Nonrandomized Patients

Author

Versteijne, Eva, Suker, Mustafa, Groen, Jesse V., Besselink, Marc G., Bonsing, Bert A., Bosscha, Koop, Busch, Olivier R., de Hingh, Ignace H. J. T., de Jong, Koert P., Molenaar, I. Quintus, van Santvoort, Hjalmar C., Verkooijen, Helena M., Van Eijck, Casper H., and van Tienhoven, Geertjan

Published
2022
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23. The Prognostic Value of Total Tumor Volume Response Compared With RECIST1.1 in Patients With Initially Unresectable Colorectal Liver Metastases Undergoing Systemic Treatment

Author

Wesdorp, Nina J., Bolhuis, Karen, Roor, Joran, van Waesberghe, Jan-Hein T. M., van Dieren, Susan, van Amerongen, Martin J., Chapelle, Thiery, Dejong, Cornelis H. C., Engelbrecht, Marc R. W., Gerhards, Michael F., Grunhagen, Dirk, van Gulik, Thomas M., Hermans, John J., de Jong, Koert P., Klaase, Joost M., Liem, Mike S. L., van Lienden, Krijn P., Molenaar, I. Quintus, Patijn, Gijs A., Rijken, Arjen M., Ruers, Theo M., Verhoef, Cornelis, de Wilt, Johannes H. W., Swijnenburg, Rutger-Jan, Punt, Cornelis J. A., Huiskens, Joost, and Kazemier, Geert

Published
2021
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24. Short-Term Outcomes of Secondary Liver Surgery for Initially Unresectable Colorectal Liver Metastases Following Modern Induction Systemic Therapy in the Dutch CAIRO5 Trial

Author

Bolhuis, Karen, Grosheide, Lodi, Wesdorp, Nina J., Komurcu, Aysun, Chapelle, Thiery, Dejong, Cornelis H. C., Gerhards, Michael F., Grünhagen, Dirk J., van Gulik, Thomas M., Huiskens, Joost, De Jong, Koert P., Kazemier, Geert, Klaase, Joost M., Liem, Mike S. L., Molenaar, I. Quintus, Patijn, Gijs A., Rijken, Arjen M., Ruers, Theo M., Verhoef, Cornelis, de Wilt, Johannes H. W., Punt, Cornelis J. A., and Swijnenburg, Rutger-Jan

Published
2021
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25. Variation in hospital mortality after pancreatoduodenectomy is related to failure to rescue rather than major complications: a nationwide audit

Author

Van Gulik, Thomas M., Festen, Sebastiaan, Karsten, Tom M., Coene, Peter P., van Rijssen, Lennart B., Zwart, Maurice J., van Dieren, Susan, de Rooij, Thijs, Bonsing, Bert A., Bosscha, Koop, van Dam, Ronald M., van Eijck, Casper H., Gerhards, Michael F., Gerritsen, Josephus J., van der Harst, Erwin, de Hingh, Ignace H., de Jong, Koert P., Kazemier, Geert, Klaase, Joost, van der Kolk, Berendina M., van Laarhoven, Cornelis J., Luyer, Misha D., Molenaar, Isaac Q., Patijn, Gijs A., Rupert, Coen G., Scheepers, Joris J., van der Schelling, George P., Vahrmeijer, Alexander L., Busch, Olivier R.C., van Santvoort, Hjalmar C., Groot Koerkamp, Bas, and Besselink, Marc G.

Published
2018
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27. First-line systemic treatment strategies in patients with initially unresectable colorectal cancer liver metastases (CAIRO5): an open-label, multicentre, randomised, controlled, phase 3 study from the Dutch Colorectal Cancer Group

Author

Bond, Marinde J G, primary, Bolhuis, Karen, additional, Loosveld, Olaf J L, additional, de Groot, Jan Willem B, additional, Droogendijk, Helga, additional, Helgason, Helgi H, additional, Hendriks, Mathijs P, additional, Klaase, Joost M, additional, Kazemier, Geert, additional, Liem, Mike S L, additional, Rijken, Arjen M, additional, Verhoef, Cornelis, additional, de Wilt, Johannes H W, additional, de Jong, Koert P, additional, Gerhards, Michael F, additional, van Amerongen, Martinus J, additional, Engelbrecht, Marc R W, additional, van Lienden, Krijn P, additional, Molenaar, I Quintus, additional, de Valk, Bart, additional, Haberkorn, Brigitte C M, additional, Kerver, Emile D, additional, Erdkamp, Frans, additional, van Alphen, Robbert J, additional, Mathijssen-van Stein, Daniëlle, additional, Komurcu, Aysun, additional, Lopez-Yurda, Marta, additional, Swijnenburg, Rutger-Jan, additional, Punt, Cornelis J A, additional, Van Gulik, Thomas, additional, Huiskens, Joost, additional, Van Tinteren, Harm, additional, Dejong, Cornelis H.C., additional, Grünhagen, Dirk J., additional, Patijn, Gijs A., additional, Ruers, Theo J.M., additional, Chapelle, Thiery, additional, Hermans, John J., additional, Leclercq, Wouter K.G., additional, Valkenburg-van Iersel, Liselot B.J., additional, Grootscholten, Cecile, additional, Van Dodewaard-de Jong, Joyce M., additional, Vincent, Jeroen, additional, Houtsma, Danny, additional, Los, Maartje, additional, Den Boer, Marien, additional, Trajkovic-Vidakovic, Marija, additional, Van Voorthuizen, Theo, additional, Koopman, Miriam, additional, Vestjens, Johanneke H.M.J.V., additional, Torrenga, Hans, additional, Mekenkamp, Leonie J., additional, Veldhuis, Gerrit Jan, additional, Polee, Marco B., additional, Dohmen, Serge E., additional, Schut, Heidi, additional, Vulink, Annelie J.E., additional, Van Halteren, Henk K., additional, Oulad Hadj, Jamal, additional, Schiphorst, Pieter-Paul J.B.M., additional, and Hoekstra, Ronald, additional

Published
2023
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28. Nationwide prospective audit of pancreatic surgery: design, accuracy, and outcomes of the Dutch Pancreatic Cancer Audit

Author

Bollen, Thomas L., Bruno, Marco J., van Tienhoven, Geert-Jan, Norduyn, Arnold, Berry, David P., Tingstedt, Bobby, Tseng, Jennifer F., Wolfgang, Christopher L., van Rijssen, L. Bengt, Koerkamp, Bas G., Zwart, Maurice J., Bonsing, Bert A., Bosscha, Koop, van Dam, Ronald M., van Eijck, Casper H., Gerhards, Michael F., van der Harst, Erwin, de Hingh, Ignace H., de Jong, Koert P., Kazemier, Geert, Klaase, Joost, van Laarhoven, Cornelis J., Molenaar, I. Quintus, Patijn, Gijs A., Rupert, Coen G., van Santvoort, Hjalmar C., Scheepers, Joris J., van der Schelling, George P., Busch, Olivier R., and Besselink, Marc G.

Published
2017
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29. mTOR Inhibition Is Most Beneficial After Liver Transplantation for Hepatocellular Carcinoma in Patients With Active Tumors

Author

Schnitzbauer, Andreas A., Filmann, Natalie, Adam, René, Bachellier, Philippe, Bechstein, Wolf O., Becker, Thomas, Bhoori, Sherrie, Bilbao, Itxarone, Brockmann, Jens, Burra, Patrizia, Chazoullières, Olivier, Cillo, Umberto, Colledan, Michele, Duvoux, Christoph, Ganten, Tom M., Gugenheim, Jean, Heise, Michael, van Hoek, Bart, Jamieson, Neville, de Jong, Koert P., Klein, Christian G., Klempnauer, Jürgen, Kneteman, Norman, Lerut, Jan, Mäkisalo, Heikki, Mazzaferro, Vincenzo, Mirza, Darius F., Nadalin, Silvio, Neuhaus, Peter, Pageaux, George-Philippe, Pinna, Antonio D., Pirenne, Jaques, Pratschke, Johann, Powel, James, Rentsch, Markus, Rizell, Magnus, Rossi, Giorgio, Rostaing, Lionel, Roy, André, Scholz, Tim, Settmacher, Utz, Soliman, Thomas, Strasser, Simone, Söderdahl, Gunnar, Troisi, Roberto I., Turrión, Victor Sánchez, Schlitt, Hans J., and Geissler, Edward K.

Published
2020
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35. ASO Visual Abstract: Intersurgeon Variability in Local Treatment Planning for Patients with Initially Unresectable Colorectal Cancer Liver Metastases—Analysis of the Liver Expert Panel of the Dutch Colorectal Cancer Group

Author

Bond, Marinde J. G., primary, Kuiper, Babette I., additional, Bolhuis, Karen, additional, Komurcu, Aysun, additional, van Amerongen, Martinus J., additional, Chapelle, Thiery, additional, Dejong, Cornelis H. C., additional, Engelbrecht, Marc R. W., additional, Gerhards, Michael F., additional, Grünhagen, Dirk J., additional, van Gulik, Thomas, additional, Hermans, John J., additional, de Jong, Koert P., additional, Klaase, Joost M., additional, Kok, Niels F. M., additional, Leclercq, Wouter K. G., additional, Liem, Mike S. L., additional, van Lienden, Krijn P., additional, Quintus Molenaar, I., additional, Neumann, Ulf P., additional, Patijn, Gijs A., additional, Rijken, Arjen M., additional, Ruers, Theo M., additional, Verhoef, Cornelis, additional, de Wilt, Johannes H. W., additional, Kazemier, Geert, additional, May, Anne M., additional, Punt, Cornelis J. A., additional, and Swijnenburg, Rutger-Jan, additional

Published
2023
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36. Variation in the management of benign liver tumors: A European survey and case vignette study

Author

Haring, Martijn P.D., primary, de Haas, Robbert J., additional, van Vilsteren, Frederike G.I., additional, Klaase, Joost M., additional, Duiker, Evelien W., additional, Blokzijl, Hans, additional, de Jong, Koert P., additional, de Meijer, Vincent E., additional, Cuperus, Frans J.C., additional, de Boer, Y.S., additional, de Man, R.A., additional, den Hoed, C.M., additional, Drenth, J.P.H., additional, Garcovich, M.G., additional, Gevers, T.J.G., additional, Klompenhouwer, A.J., additional, Kramer, M., additional, Tushuizen, M.E., additional, van der Meer, A.J., additional, Burgmans, M.C., additional, Cannella, R.C., additional, Caseiro-Alves, F.C., additional, Denecke, T.D., additional, Dwarkasing, R.S., additional, Fehrenbach, U.F., additional, Feshtali, S., additional, Miclea, R.L., additional, Poyanli, A.P., additional, Ronot, M.R., additional, Sartoris, R.S., additional, Thomeer, Maarten, additional, van der Leij, C., additional, van Koeverden, S.K., additional, Vermersch, M.V., additional, Vernuccio, F.V., additional, Willemssen, F.E.J.A., additional, Addeo, P.A., additional, Alexandrino, H., additional, Belli, A., additional, Bemelmans, M.H.A., additional, Boleslawski, E.B., additional, Coelen, R.J.S., additional, de Boer, M.T., additional, de Kleine, R.H., additional, den Dulk, M., additional, Frilling, A.F., additional, Furumaya, A., additional, Irinel, I.P., additional, Regimbeau, J.M., additional, Manuela, M.C., additional, Özden, İ., additional, Sallinen, V.S., additional, Schaapherder, A.F., additional, Schmelzle, M.S., additional, Seehofer, D., additional, Trotovšek, B., additional, Truant, S.T., additional, van den Boezem, P.B., additional, and van Rosmalen, B.V., additional

Published
2023
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37. A dual-tracer approach using [11C]CH and [18F]FDG in HCC clinical decision making

Author

Veenstra, E, Ruiter, S, de Haas, R, de Jong, K, Erba, P, Dierckx, R, Noordzij, W, Veenstra, Emile B, Ruiter, Simeon J S, de Haas, Robbert J, de Jong, Koert P, Erba, Paola A, Dierckx, Rudi A J O, Noordzij, Walter, Veenstra, E, Ruiter, S, de Haas, R, de Jong, K, Erba, P, Dierckx, R, Noordzij, W, Veenstra, Emile B, Ruiter, Simeon J S, de Haas, Robbert J, de Jong, Koert P, Erba, Paola A, Dierckx, Rudi A J O, and Noordzij, Walter

Abstract

Background: Early detection of recurrent or progressive HCC remains the strongest prognostic factor for survival. Dual tracer PET/CT imaging with [11C]CH and [18F]FDG can further increase detection rates as both tracers entail different metabolic pathways involved in HCC development. We investigated dual-tracer PET/CT in clinical decision making in patients suspected of recurrent or progressive HCC. All HCC patients who underwent both [11C]CH and [18F]FDG PET/CT in our institute from February 2018 to December 2021 were included. Both tracer PET/CT were within 4 weeks of each other with at least 6-month follow-up. Patients underwent dual tracer PET/CT because of unexplained and suspicious CT/MRI or sudden rise of serum tumour markers. A detected lesion was considered critical when the finding had prognostic consequences leading to treatment changes. Results: Nineteen patients who underwent [11C]CH and [18F]FDG PET/CT were included of which all but six patients were previously treated for HCC. Dual-tracer critical finding detection rate was 95%, with [18F]FDG 68%, and [11C]CH 84%. Intrahepatic HCC recurrence finding rate was 65% for both tracers. [18F]FDG found more ablation site recurrences (4/5) compared to [11C]CH (2/5). Only [11C]CH found two needle tract metastases. Both tracers found 75% of the positive lymph nodes. Two new primary tumours were found, one by [18F]FDG and both by [11C]CH. Conclusions: Our study favours a dual-tracer approach in HCC staging in high-risk patients or when conventional imaging is non-conclusive.

Published
2023

38. Intersurgeon Variability in Local Treatment Planning for Patients with Initially Unresectable Colorectal Cancer Liver Metastases:Analysis of the Liver Expert Panel of the Dutch Colorectal Cancer Group

Author

Bond, Marinde J.G., Kuiper, Babette I., Bolhuis, Karen, Komurcu, Aysun, van Amerongen, Martinus J., Chapelle, Thiery, Dejong, Cornelis H.C., Engelbrecht, Marc R.W., Gerhards, Michael F., Grünhagen, Dirk J., van Gulik, Thomas, Hermans, John J., de Jong, Koert P., Klaase, Joost M., Kok, Niels F.M., Leclercq, Wouter K.G., Liem, Mike S.L., van Lienden, Krijn P., Molenaar, I. Quintus, Neumann, Ulf P., Patijn, Gijs A., Rijken, Arjen M., Ruers, Theo M., Verhoef, Cornelis, de Wilt, Johannes H.W., Kazemier, Geert, May, Anne M., Punt, Cornelis J.A., Swijnenburg, Rutger Jan, Bond, Marinde J.G., Kuiper, Babette I., Bolhuis, Karen, Komurcu, Aysun, van Amerongen, Martinus J., Chapelle, Thiery, Dejong, Cornelis H.C., Engelbrecht, Marc R.W., Gerhards, Michael F., Grünhagen, Dirk J., van Gulik, Thomas, Hermans, John J., de Jong, Koert P., Klaase, Joost M., Kok, Niels F.M., Leclercq, Wouter K.G., Liem, Mike S.L., van Lienden, Krijn P., Molenaar, I. Quintus, Neumann, Ulf P., Patijn, Gijs A., Rijken, Arjen M., Ruers, Theo M., Verhoef, Cornelis, de Wilt, Johannes H.W., Kazemier, Geert, May, Anne M., Punt, Cornelis J.A., and Swijnenburg, Rutger Jan

Abstract

Background: Consensus on resectability criteria for colorectal cancer liver metastases (CRLM) is lacking, resulting in differences in therapeutic strategies. This study evaluated variability of resectability assessments and local treatment plans for patients with initially unresectable CRLM by the liver expert panel from the randomised phase III CAIRO5 study. Methods: The liver panel, comprising surgeons and radiologists, evaluated resectability by predefined criteria at baseline and 2-monthly thereafter. If surgeons judged CRLM as resectable, detailed local treatment plans were provided. The panel chair determined the conclusion of resectability status and local treatment advice, and forwarded it to local surgeons. Results: A total of 1149 panel evaluations of 496 patients were included. Intersurgeon disagreement was observed in 50% of evaluations and was lower at baseline than follow-up (36% vs. 60%, p < 0.001). Among surgeons in general, votes for resectable CRLM at baseline and follow-up ranged between 0–12% and 27–62%, and for permanently unresectable CRLM between 3–40% and 6–47%, respectively. Surgeons proposed different local treatment plans in 77% of patients. The most pronounced intersurgeon differences concerned the advice to proceed with hemihepatectomy versus parenchymal-preserving approaches. Eighty-four percent of patients judged by the panel as having resectable CRLM indeed received local treatment. Local surgeons followed the technical plan proposed by the panel in 40% of patients. Conclusion: Considerable variability exists among expert liver surgeons in assessing resectability and local treatment planning of initially unresectable CRLM. This stresses the value of panel-based decisions, and the need for consensus guidelines on resectability criteria and technical approach to prevent unwarranted variability in clinical practice.

Published
2023

39. The role of tumour biological factors in technical anatomical resectability assessment of colorectal liver metastases following induction systemic treatment:An analysis of the Dutch CAIRO5 trial

Author

Bolhuis, Karen, Bond, Marinde J.G., Van Amerongen, Martin J., Komurcu, Aysun, Chapelle, Thiery, Dejong, Cornelis H.C., Engelbrecht, Marc R.W., Gerhards, Michael F., Grünhagen, Dirk J., van Gulik, Thomas M., Hermans, John J., De Jong, Koert P., Kazemier, Geert, Klaase, Joost M., Kok, Niels F.M., Leclercq, Wouter K.G., Liem, Mike S.L., van Lienden, Krijn P., Molenaar, I. Quintus, Neumann, Ulf P., Patijn, Gijs A., Rijken, Arjen M., Ruers, Theo M., Verhoef, Cornelis, de Wilt, Johannes H.W., May, Anne M., Punt, Cornelis J.A., Swijnenburg, Rutger Jan, Bolhuis, Karen, Bond, Marinde J.G., Van Amerongen, Martin J., Komurcu, Aysun, Chapelle, Thiery, Dejong, Cornelis H.C., Engelbrecht, Marc R.W., Gerhards, Michael F., Grünhagen, Dirk J., van Gulik, Thomas M., Hermans, John J., De Jong, Koert P., Kazemier, Geert, Klaase, Joost M., Kok, Niels F.M., Leclercq, Wouter K.G., Liem, Mike S.L., van Lienden, Krijn P., Molenaar, I. Quintus, Neumann, Ulf P., Patijn, Gijs A., Rijken, Arjen M., Ruers, Theo M., Verhoef, Cornelis, de Wilt, Johannes H.W., May, Anne M., Punt, Cornelis J.A., and Swijnenburg, Rutger Jan

Abstract

Background: Large inter-surgeon variability exists in technical anatomical resectability assessment of colorectal cancer liver-only metastases (CRLM) following induction systemic therapy. We evaluated the role of tumour biological factors in predicting resectability and (early) recurrence after surgery for initially unresectable CRLM. Methods: 482 patients with initially unresectable CRLM from the phase 3 CAIRO5 trial were selected, with two-monthly resectability assessments by a liver expert panel. If no consensus existed among panel surgeons (i.e. same vote for (un)resectability of CRLM), conclusion was based on majority. The association of tumour biological (sidedness, synchronous CRLM, carcinoembryonic antigen and RAS/BRAFV600E mutation status) and technical anatomical factors with consensus among panel surgeons, secondary resectability and early recurrence (<6 months) without curative-intent repeat local treatment was analysed by uni- and pre-specified multivariable logistic regression. Results: After systemic treatment, 240 (50%) patients received complete local treatment of CRLM of which 75 (31%) patients experienced early recurrence without repeat local treatment. Higher number of CRLM (odds ratio 1.09 [95% confidence interval 1.03–1.15]) and age (odds ratio 1.03 [95% confidence interval 1.00–1.07]) were independently associated with early recurrence without repeat local treatment. In 138 (52%) patients, no consensus among panel surgeons was present prior to local treatment. Postoperative outcomes in patients with and without consensus were comparable. Conclusions: Almost a third of patients selected by an expert panel for secondary CRLM surgery following induction systemic treatment experience an early recurrence only amenable to palliative treatment. Number of CRLM and age, but no tumour biological factors are predictive, suggesting that until there are better biomarkers; resectability assessment remains primarily a technical anatomical de

Published
2023

40. A nationwide assessment of hepatocellular adenoma resection:Indications and pathological discordance

Author

Haring, Martijn P D, Elfrink, Arthur K E, Oudmaijer, Christiaan A J, Andel, Paul C M, Furumaya, Alicia, de Jong, Nenke, Willems, Colin J J M, Huits, Thijs, Sijmons, Julie M L, Belt, Eric J T, Bosscha, Koop, Consten, Esther C J, Coolsen, Mariëlle M E, van Duijvendijk, Peter, Erdmann, Joris I, Gobardhan, Paul, de Haas, Robbert J, van Heek, Tjarda, Lam, Hwai-Ding, Leclercq, Wouter K G, Liem, Mike S L, Marsman, Hendrik A, Patijn, Gijs A, Terkivatan, Türkan, Zonderhuis, Babs M, Molenaar, Izaak Quintus, Te Riele, Wouter W, Hagendoorn, Jeroen, Schaapherder, Alexander F M, IJzermans, Jan N M, Buis, Carlijn I, Klaase, Joost M, de Jong, Koert P, de Meijer, Vincent E, Haring, Martijn P D, Elfrink, Arthur K E, Oudmaijer, Christiaan A J, Andel, Paul C M, Furumaya, Alicia, de Jong, Nenke, Willems, Colin J J M, Huits, Thijs, Sijmons, Julie M L, Belt, Eric J T, Bosscha, Koop, Consten, Esther C J, Coolsen, Mariëlle M E, van Duijvendijk, Peter, Erdmann, Joris I, Gobardhan, Paul, de Haas, Robbert J, van Heek, Tjarda, Lam, Hwai-Ding, Leclercq, Wouter K G, Liem, Mike S L, Marsman, Hendrik A, Patijn, Gijs A, Terkivatan, Türkan, Zonderhuis, Babs M, Molenaar, Izaak Quintus, Te Riele, Wouter W, Hagendoorn, Jeroen, Schaapherder, Alexander F M, IJzermans, Jan N M, Buis, Carlijn I, Klaase, Joost M, de Jong, Koert P, and de Meijer, Vincent E

Abstract

Hepatocellular adenomas (HCAs) are benign liver tumors associated with bleeding or malignant transformation. Data on the indication for surgery are scarce. We analyzed indications and outcome of patients operated for HCAs < 50 mm compared to HCAs ≥ 50 mm. Changes in final postoperative diagnosis were assessed. We performed a retrospective study that included patients who underwent resection for (suspected) HCAs in the Netherlands from 2014 to 2019. Indication for resection was analyzed and stratified for small (<50 mm) and large (≥50 mm) tumors. Logistic regression analysis was performed on factors influencing change in tumor diagnosis. Out of 222 patients who underwent surgery, 44 (20%) patients had a tumor <50 mm. Median age was 46 (interquartile range [IQR], 33-56) years in patients with small tumors and 37 (IQR, 31-46) years in patients with large tumors (p = 0.016). Patients with small tumors were more frequently men (21% vs. 5%, p = 0.002). Main indications for resection in patients with small tumors were suspicion of (pre)malignancy (55%), (previous) bleeding (14%), and male sex (11%). Patients with large tumors received operations because of tumor size >50 mm (52%), suspicion of (pre)malignancy (28%), and (previous) bleeding (5.1%). No difference was observed in HCA-subtype distribution between small and large tumors. Ninety-six (43%) patients had a postoperative change in diagnosis. Independent risk factors for change in diagnosis were tumor size <50 mm (adjusted odds ratio [aOR], 3.4; p < 0.01), male sex (aOR, 3.7; p = 0.03), and lack of hepatobiliary contrast-enhanced magnetic resonance imaging (CE-MRI) (aOR, 1.8; p = 0.04). Resection for small (suspected) HCAs was mainly indicated by suspicion of (pre)malignancy, whereas for large (suspected) HCAs, tumor size was the most prevalent indication. Male sex, tumor size <50 mm, and lack of hepatobiliary CE-MRI were independent risk factors for postoperative change in tumor diagnosis.

Published
2023

41. Deep learning models for automatic tumor segmentation and total tumor volume assessment in patients with colorectal liver metastases

Author

MS CGO, Cancer, Epi Kanker Team B, Wesdorp, Nina J., Zeeuw, J. Michiel, Postma, Sam C.J., Roor, Joran, van Waesberghe, Jan Hein T.M., van den Bergh, Janneke E., Nota, Irene M., Moos, Shira, Kemna, Ruby, Vadakkumpadan, Fijoy, Ambrozic, Courtney, van Dieren, Susan, van Amerongen, Martinus J., Chapelle, Thiery, Engelbrecht, Marc R.W., Gerhards, Michael F., Grunhagen, Dirk, van Gulik, Thomas M., Hermans, John J., de Jong, Koert P., Klaase, Joost M., Liem, Mike S.L., van Lienden, Krijn P., Molenaar, I. Quintus, Patijn, Gijs A., Rijken, Arjen M., Ruers, Theo M., Verhoef, Cornelis, de Wilt, Johannes H.W., Marquering, Henk A., Stoker, Jaap, Swijnenburg, Rutger Jan, Punt, Cornelis J.A., Huiskens, Joost, Kazemier, Geert, MS CGO, Cancer, Epi Kanker Team B, Wesdorp, Nina J., Zeeuw, J. Michiel, Postma, Sam C.J., Roor, Joran, van Waesberghe, Jan Hein T.M., van den Bergh, Janneke E., Nota, Irene M., Moos, Shira, Kemna, Ruby, Vadakkumpadan, Fijoy, Ambrozic, Courtney, van Dieren, Susan, van Amerongen, Martinus J., Chapelle, Thiery, Engelbrecht, Marc R.W., Gerhards, Michael F., Grunhagen, Dirk, van Gulik, Thomas M., Hermans, John J., de Jong, Koert P., Klaase, Joost M., Liem, Mike S.L., van Lienden, Krijn P., Molenaar, I. Quintus, Patijn, Gijs A., Rijken, Arjen M., Ruers, Theo M., Verhoef, Cornelis, de Wilt, Johannes H.W., Marquering, Henk A., Stoker, Jaap, Swijnenburg, Rutger Jan, Punt, Cornelis J.A., Huiskens, Joost, and Kazemier, Geert

Published
2023

42. ASO Visual Abstract: Intersurgeon Variability in Local Treatment Planning for Patients with Initially Unresectable Colorectal Cancer Liver Metastases-Analysis of the Liver Expert Panel of the Dutch Colorectal Cancer Group

Author

Epi Kanker Team B, Cancer, MS CGO, Epi Kanker, JC onderzoeksprogramma Kanker, Bond, Marinde J G, Kuiper, Babette I, Bolhuis, Karen, Komurcu, Aysun, van Amerongen, Martinus J, Chapelle, Thiery, Dejong, Cornelis H C, Engelbrecht, Marc R W, Gerhards, Michael F, Grünhagen, Dirk J, van Gulik, Thomas, Hermans, John J, de Jong, Koert P, Klaase, Joost M, Kok, Niels F M, Leclercq, Wouter K G, Liem, Mike S L, van Lienden, Krijn P, Quintus Molenaar, I, Neumann, Ulf P, Patijn, Gijs A, Rijken, Arjen M, Ruers, Theo M, Verhoef, Cornelis, de Wilt, Johannes H W, Kazemier, Geert, May, Anne M, Punt, Cornelis J A, Swijnenburg, Rutger-Jan, Epi Kanker Team B, Cancer, MS CGO, Epi Kanker, JC onderzoeksprogramma Kanker, Bond, Marinde J G, Kuiper, Babette I, Bolhuis, Karen, Komurcu, Aysun, van Amerongen, Martinus J, Chapelle, Thiery, Dejong, Cornelis H C, Engelbrecht, Marc R W, Gerhards, Michael F, Grünhagen, Dirk J, van Gulik, Thomas, Hermans, John J, de Jong, Koert P, Klaase, Joost M, Kok, Niels F M, Leclercq, Wouter K G, Liem, Mike S L, van Lienden, Krijn P, Quintus Molenaar, I, Neumann, Ulf P, Patijn, Gijs A, Rijken, Arjen M, Ruers, Theo M, Verhoef, Cornelis, de Wilt, Johannes H W, Kazemier, Geert, May, Anne M, Punt, Cornelis J A, and Swijnenburg, Rutger-Jan

Published
2023

43. Intersurgeon Variability in Local Treatment Planning for Patients with Initially Unresectable Colorectal Cancer Liver Metastases: Analysis of the Liver Expert Panel of the Dutch Colorectal Cancer Group

Author

Epi Kanker Team B, Cancer, MS CGO, Epi Kanker, JC onderzoeksprogramma Kanker, Bond, Marinde J G, Kuiper, Babette I, Bolhuis, Karen, Komurcu, Aysun, van Amerongen, Martinus J, Chapelle, Thiery, Dejong, Cornelis H C, Engelbrecht, Marc R W, Gerhards, Michael F, Grünhagen, Dirk J, van Gulik, Thomas, Hermans, John J, de Jong, Koert P, Klaase, Joost M, Kok, Niels F M, Leclercq, Wouter K G, Liem, Mike S L, van Lienden, Krijn P, Molenaar, I Quintus, Neumann, Ulf P, Patijn, Gijs A, Rijken, Arjen M, Ruers, Theo M, Verhoef, Cornelis, de Wilt, Johannes H W, Kazemier, Geert, May, Anne M, Punt, Cornelis J A, Swijnenburg, Rutger-Jan, Epi Kanker Team B, Cancer, MS CGO, Epi Kanker, JC onderzoeksprogramma Kanker, Bond, Marinde J G, Kuiper, Babette I, Bolhuis, Karen, Komurcu, Aysun, van Amerongen, Martinus J, Chapelle, Thiery, Dejong, Cornelis H C, Engelbrecht, Marc R W, Gerhards, Michael F, Grünhagen, Dirk J, van Gulik, Thomas, Hermans, John J, de Jong, Koert P, Klaase, Joost M, Kok, Niels F M, Leclercq, Wouter K G, Liem, Mike S L, van Lienden, Krijn P, Molenaar, I Quintus, Neumann, Ulf P, Patijn, Gijs A, Rijken, Arjen M, Ruers, Theo M, Verhoef, Cornelis, de Wilt, Johannes H W, Kazemier, Geert, May, Anne M, Punt, Cornelis J A, and Swijnenburg, Rutger-Jan

Published
2023

46. Alternative Fistula Risk Score for Pancreatoduodenectomy (a-FRS): Design and International External Validation

Author

Mungroop, Timothy H., van Rijssen, L. Bengt, van Klaveren, David, Smits, F. Jasmijn, van Woerden, Victor, Linnemann, Ralph J., de Pastena, Matteo, Klompmaker, Sjors, Marchegiani, Giovanni, Ecker, Brett L., van Dieren, Susan, Bonsing, Bert, Busch, Olivier R., van Dam, Ronald M., Erdmann, Joris, van Eijck, Casper H., Gerhards, Michael F., van Goor, Harry, van der Harst, Erwin, de Hingh, Ignace H., de Jong, Koert P., Kazemier, Geert, Luyer, Misha, Shamali, Awad, Barbaro, Salvatore, Armstrong, Thomas, Takhar, Arjun, Hamady, Zaed, Klaase, Joost, Lips, Daan J., Molenaar, I. Quintus, Nieuwenhuijs, Vincent B., Rupert, Coen, van Santvoort, Hjalmar C., Scheepers, Joris J., van der Schelling, George P., Bassi, Claudio, Vollmer, Charles M., Steyerberg, Ewout W., Abu Hilal, Mohammed, Groot Koerkamp, Bas, and Besselink, Marc G.

Published
2019
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48. Three-year results of renal function in liver transplant recipients on low-dose sirolimus and tacrolimus: a multicenter, randomized, controlled trial

Author

Mulder, Midas B., primary, van Hoek, Bart, additional, van den Berg, Aad P., additional, Polak, Wojciech G., additional, Alwayn, Ian P.J., additional, de Jong, Koert P., additional, de Winter, Brenda C.M., additional, Verhey-Hart, Elke, additional, Erler, Nicole S., additional, den Hoed, Caroline M., additional, and Metselaar, Herold J., additional

Published
2023
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