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5 results on '"Jiménez-Alonso, Juan Francisco"'

1. Association between perceived level of stress, clinical characteristics and psychopathological symptoms in women with systemic lupus erythematosus

Author

Peralta-Ramírez, María Isabel, Pérez-Mármol, José Manuel, Castañeda-Cabestany, Margarita, Santos-Ruiz, Ana, Montero-López, Eva, Callejas-Rubio, José Luis, Navarrete-Navarrete, Nuria, Fernández-Sánchez, José Carlos, Jiménez-Alonso, Juan Francisco, Ortego-Centeno, Norberto, Sabio, José Mario, García-Morales, Marta, Universidad de Alicante. Departamento de Psicología de la Salud, Calidad de Vida, Bienestar Psicológico y Salud, and Psicología Aplicada a la Salud y Comportamiento Humano (PSYBHE)

Subjects
Systemic lupus erythematosus, Psychological stress, Risk factors, Psychopathology, immune system diseases, Psicología Básica
Abstract

Objective: To evaluate psychopathological status and stress level from a sample with SLE; compare mental functioning and stress levels between women with SLE and healthy women; determine whether disease duration, disease activity, cumulative organ damage and stress have an influence on psychopathological symptoms in SLE patients; and evaluate whether perception of stress is related to SLE severity. Methods: We conducted a cross-sectional study of 425 participants; 202 women with SLE, with an average age (SD) of 36.61 (10.15), and 223 healthy women, with age-matched controls. The assessment included the clinical characteristics (disease duration, SLE activity, cumulative organ damage, pharmacotherapy), the Symptom Checklist-90-Revised (SCL-90-R) and the Perceived Stress Scale. Descriptive, comparative, univariate and multivariate analysis were performed. Results: SLE patients showed psychopathological alterations in the somatisation, obsessive-compulsive and positive discomfort subscales of SCL-90-R. Women with SLE reported significantly higher scores on the psychopathological dimensions and perceived stress compared to healthy women, except for paranoid ideation. Disease duration, SLE activity, cumulative organ damage, and perceived stress were shown to be significant predictors of psychopathological manifestations, explaining a range, between 20 and 43%, of variance across SCL-90-R dimensions. Moreover, perceived stress was related to SLE activity, after controlling for psychopathological dimensions. Conclusion: The psychopathological manifestations in SLE appeared to be influenced by perceived stress, disease duration, disease activity and cumulative organ damage. In turn, perceived stress was associated with disease severity. This knowledge may contribute to a more comprehensive perspective of these manifestations in the SLE population in the clinical setting. This research was developed in the framework of the I+D Project “SEJ2007-61857” and the I+D Project ‘‘PSI2010- 15780’’, funded by the Spanish Ministry of Education and Science. In addition, this study was supported by the Andalusian Health Service (grant no. PI-0059/2007).

Published
2018

2. Association between perceived level of stress, clinical characteristics and psychopathological symptoms in women with systemic lupus erythematosus

Author

Universidad de Alicante. Departamento de Psicología de la Salud, Peralta-Ramírez, María Isabel, Pérez-Mármol, José Manuel, Castañeda-Cabestany, Margarita, Santos-Ruiz, Ana, Montero-López, Eva, Callejas-Rubio, José Luis, Navarrete-Navarrete, Nuria, Fernández-Sánchez, José Carlos, Jiménez-Alonso, Juan Francisco, Ortego-Centeno, Norberto, Sabio, José Mario, García-Morales, Marta, Universidad de Alicante. Departamento de Psicología de la Salud, Peralta-Ramírez, María Isabel, Pérez-Mármol, José Manuel, Castañeda-Cabestany, Margarita, Santos-Ruiz, Ana, Montero-López, Eva, Callejas-Rubio, José Luis, Navarrete-Navarrete, Nuria, Fernández-Sánchez, José Carlos, Jiménez-Alonso, Juan Francisco, Ortego-Centeno, Norberto, Sabio, José Mario, and García-Morales, Marta

Abstract

Objective: To evaluate psychopathological status and stress level from a sample with SLE; compare mental functioning and stress levels between women with SLE and healthy women; determine whether disease duration, disease activity, cumulative organ damage and stress have an influence on psychopathological symptoms in SLE patients; and evaluate whether perception of stress is related to SLE severity. Methods: We conducted a cross-sectional study of 425 participants; 202 women with SLE, with an average age (SD) of 36.61 (10.15), and 223 healthy women, with age-matched controls. The assessment included the clinical characteristics (disease duration, SLE activity, cumulative organ damage, pharmacotherapy), the Symptom Checklist-90-Revised (SCL-90-R) and the Perceived Stress Scale. Descriptive, comparative, univariate and multivariate analysis were performed. Results: SLE patients showed psychopathological alterations in the somatisation, obsessive-compulsive and positive discomfort subscales of SCL-90-R. Women with SLE reported significantly higher scores on the psychopathological dimensions and perceived stress compared to healthy women, except for paranoid ideation. Disease duration, SLE activity, cumulative organ damage, and perceived stress were shown to be significant predictors of psychopathological manifestations, explaining a range, between 20 and 43%, of variance across SCL-90-R dimensions. Moreover, perceived stress was related to SLE activity, after controlling for psychopathological dimensions. Conclusion: The psychopathological manifestations in SLE appeared to be influenced by perceived stress, disease duration, disease activity and cumulative organ damage. In turn, perceived stress was associated with disease severity. This knowledge may contribute to a more comprehensive perspective of these manifestations in the SLE population in the clinical setting.

Published
2018

3. Espectro mutacional y caracterización funcional y clínica de nuevas mutaciones genéticas en canalopatías cardíacas

Author

Jiménez Jáimez, Juan, Jiménez-Alonso, Juan, Ramírez-Hernández, José Antonio, Universidad de Granada. Departamento de Medicina, Jiménez Alonso, Juan Francisco, and Ramírez Hernández, José Antonio

Subjects
Corazón, Medicina, 616.12, Enfermedades cardiovasculares, Canalopatías, Genética, Mutación (Biología)
Abstract

Tesis Univ. Granada. Departamento de Medicina

Published
2018

4. Radiosensibilidad in vitro en pacientes con lupus eritematoso

Author

Carrillo Alascio, Pedro Luis, Jiménez-Alonso, Juan, Núñez Torres, María Isabel, López Ramírez, María Escarlata, Universidad de Granada. Departamento de Medicina, and Jiménez Alonso, Juan Francisco

Subjects
Lupus eritematoso
Abstract

Tesis Univ. Granada. Departamento de Medicina. Leída el 25 de junio de 2008

Published
2018

5. Association between perceived level of stress, clinical characteristics and psychopathological symptoms in women with systemic lupus erythematosus.

Author

Peralta-Ramírez MI, Pérez-Mármol JM, Castañeda-Cabestany M, Santos-Ruiz AM, Montero-López E, Callejas-Rubio JL, Navarrete-Navarrete N, Fernández-Sánchez JC, Jiménez-Alonso JF, Ortego-Centeno N, Sabio JM, and García-Morales M

Subjects
Adult, Antimalarials therapeutic use, Anxiety psychology, Case-Control Studies, Cross-Sectional Studies, Depression psychology, Female, Glucocorticoids therapeutic use, Hostility, Humans, Immunosuppressive Agents therapeutic use, Lupus Erythematosus, Systemic complications, Lupus Erythematosus, Systemic drug therapy, Lupus Erythematosus, Systemic psychology, Middle Aged, Multivariate Analysis, Obsessive-Compulsive Disorder psychology, Paranoid Disorders psychology, Perception, Psychotic Disorders psychology, Somatoform Disorders psychology, Stress, Psychological complications, Stress, Psychological psychology, Lupus Erythematosus, Systemic physiopathology, Stress, Psychological physiopathology
Abstract

Objectives: To evaluate psychopathological status and stress level from a sample with SLE; compare mental functioning and stress levels between women with SLE and healthy women; determine whether disease duration, disease activity, cumulative organ damage and stress have an influence on psychopathological symptoms in SLE patients; and evaluate whether perception of stress is related to SLE severity., Methods: We conducted a cross-sectional study of 425 participants; 202 women with SLE, with an average age (SD) of 36.61 (10.15), and 223 healthy women, with age-matched controls. The assessment included the clinical characteristics (disease duration, SLE activity, cumulative organ damage, pharmacotherapy), the Symptom Checklist-90-Revised (SCL-90-R) and the Perceived Stress Scale. Descriptive, comparative, univariate and multivariate analysis were performed., Results: SLE patients showed psychopathological alterations in the somatisation, obsessive-compulsive and positive discomfort subscales of SCL-90-R. Women with SLE reported significantly higher scores on the psychopathological dimensions and perceived stress compared to healthy women, except for paranoid ideation. Disease duration, SLE activity, cumulative organ damage, and perceived stress were shown to be significant predictors of psychopathological manifestations, explaining a range, between 20 and 43%, of variance across SCL-90-R dimensions. Moreover, perceived stress was related to SLE activity, after controlling for psychopathological dimensions., Conclusions: The psychopathological manifestations in SLE appeared to be influenced by perceived stress, disease duration, disease activity and cumulative organ damage. In turn, perceived stress was associated with disease severity. This knowledge may contribute to a more comprehensive perspective of these manifestations in the SLE population in the clinical setting.

Published
2018

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