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1. Abstract 4137665: Getting to the Heart of StrokeTM: A Novel American Heart Association Initiative Which Increases Identification of Stroke Etiology and Evidence-Based Post-Stroke Evaluation by Strengthening Cardiology and Neurology Collaboration

Author

Jauch, Edward, Baird, Ali, Witt, John, Bailey, Alison, Lakkireddy, Dhanunjaya, Schneider, Alexander, Stergar, Lindsay, Orndorff, Kevin, Harper, Russell, Thomas, Kathie, Beon, Chandler, and Manoukian, Steven

Published
2024
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2. The Utility of Domain-Specific End Points in Acute Stroke Trials

Author

Cramer, Steven C, Wolf, Steven L, Saver, Jeffrey L, Johnston, Karen C, Mocco, J, Lansberg, Maarten G, Savitz, Sean I, Liebeskind, David S, Smith, Wade, Wintermark, Max, Elm, Jordan J, Khatri, Pooja, Broderick, Joseph P, Janis, Scott, Chen, Daofen, Dromerick, Alexander, Dunning, Kari, Grande, Andrew W, Marshall, Randolph S, Meinzer, Caitlyn, Page, Stephen, Reiss, Aimee, Richards, Lorie, Wechsler, Lawrence, Winstein, Carolee, Bushnell, Cheryl, Edwards, Dorothy, Lo, Warren, Lee, Jin-Moo, Amlie-Lefond, Catherine M, Albers, Gregory W, Dempsey, Robert, Gropen, Toby I, Jauch, Edward C, Leira, Enrique C, Martin, Renee, Meyer, Brett C, Schindler, Kiva, Scott, Phillip, Singhal, Aneesh B, and Moy, Claudia S

Subjects
Biomedical and Clinical Sciences, Allied Health and Rehabilitation Science, Clinical Sciences, Health Sciences, Neurosciences, Endpoint Determination, Humans, Research Design, Stroke, Treatment Outcome, brain, infarction, neurons, outcome assessment, reperfusion, NIH StrokeNet Recovery and Rehabilitation Group and the Acute Stroke Group*, Cardiorespiratory Medicine and Haematology, Neurology & Neurosurgery, Clinical sciences, Allied health and rehabilitation science
Abstract

Domain-specific endpoints are assessments that correspond to the output of individual neural systems and are useful for capturing treatment effects on specific behaviors. By contrast, global endpoints combine several attributes into a single score and are useful for capturing broad treatment effects in a summary way. While global endpoints have become the de facto mechanism required to define benefit in stroke trials, they also have important limitations, some of which might be addressed by simultaneously measuring domain-specific endpoints. Substantial opportunity remains to identify quantifiable patient benefit that would otherwise not be captured by global endpoints. Potential advantages of incorporating domain-specific endpoints in acute stroke trials are discussed, such as increased granularity of measurement, improved understanding of how therapies affect the brain between acute treatment and day 90, and optimized therapeutic translation. Potential disadvantages are also considered, including time and cost of administering domain-specific endpoints, as well as statistical implications. Domain-specific endpoints and global endpoints are not mutually exclusive, and both capture clinical benefits to patients. Incorporating a broader set of outcome assessments in stroke trials, including both global and domain-specific endpoints, is warranted.

Published
2021

3. Enhancing Enrollment in Acute Stroke Trials: Current State and Consensus Recommendations

Author

Broderick, Joseph P., Silva, Gisele Sampaio, Selim, Magdy, Kasner, Scott E., Aziz, Yasmin, Sutherland, Jocelyn, Jauch, Edward C., Adeoye, Opeolu M., Hill, Michael D., Mistry, Eva A., Lyden, Patrick D., Mocco, J, Smith, Elaine M., Hernandez-Jimenez, Macarena, Deljkich, Emir, Kamel, Hooman, Alemseged, Fana, Bates, Karen, Bhatt, Nirav R., Boltze, Johannes, Campbell, Bruce C.V., Favilla, Christopher, Fiorella, David, Grotta, James, Haddad, Walid, Heidt, Jeremy J., Liebeskind, David S., Lightfoot, Nathan, Jubin, Ronald, Khatri, Pooja, Lansberg, Maarten G., Lynch, John, Margolin, David H., Nguyen, Thanh N., Nogueira, Raul G., Samaniego, Edgar A., Saver, Jeffrey, Schwamm, Lee H., Sheth, Kevin N., Smith, Wendy J., Wadhwa, Manish, Wakhloo, Ajay K., Wechsler, Lawrence R., Xiong, Yunyun, and Zachrison, Kori S.

Published
2023
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4. De Garengeot Hernia Diagnosed with Point-of-care Ultrasound

Author

Jennings, Lindsey, Presley, Brad, and Jauch, Edward

Abstract

De Garengeot hernias, defined as a femoral hernia containing the appendix, are rare. It is even uncommon to have an incarcerated de Garengeot hernia with associated acute appendicitis. We report a case of a 76-year-old female presenting to the emergency department for a right lower quadrant abdominal mass for four days. Physical exam was consistent with an incarcerated hernia. A point-of-care ultrasound revealed a non-compressible, blind-ended loop of bowel within the hernia sac, concerning for acute appendicitis within the mass. Computed tomography of the abdomen and pelvis confirmed the diagnosis of acute appendicitis within a femoral hernia.

Published
2019

7. Translational Stroke Research

Author

Bosetti, Francesca, Koenig, James I, Ayata, Cenk, Back, Stephen A, Becker, Kyra, Broderick, Joseph P, Carmichael, S Thomas, Cho, Sunghee, Cipolla, Marilyn J, Corbett, Dale, Corriveau, Roderick A, Cramer, Steven C, Ferguson, Adam R, Finklestein, Seth P, Ford, Byron D, Furie, Karen L, Hemmen, Thomas M, Iadecola, Costantino, Jakeman, Lyn B, Janis, Scott, Jauch, Edward C, Johnston, Karen C, Kochanek, Patrick M, Kohn, Harold, Lo, Eng H, Lyden, Patrick D, Mallard, Carina, McCullough, Louise D, McGavern, Linda M, Meschia, James F, Moy, Claudia S, Perez-Pinzon, Miguel A, Ramadan, Ipolia, Savitz, Sean I, Schwamm, Lee H, Steinberg, Gary K, Stenzel-Poore, Mary P, Tymianski, Michael, Warach, Steven, Wechsler, Lawrence R, Zhang, John H, and Koroshetz, Walter

Subjects
Age Factors, Animals, Chronic Disease, Comorbidity, Disease Models, Animal, Humans, Recovery of Function, Research, Sex Factors, Stroke, Thrombectomy, Thrombolytic Therapy, Translational Research, Biomedical, animal model, biomarker, outcome, recovery, reperfusion, Cardiorespiratory Medicine and Haematology, Clinical Sciences, Neurosciences, Neurology & Neurosurgery
Published
2017

8. Translational Stroke Research: Vision and Opportunities.

Author

Bosetti, Francesca, Koenig, James I, Ayata, Cenk, Back, Stephen A, Becker, Kyra, Broderick, Joseph P, Carmichael, S Thomas, Cho, Sunghee, Cipolla, Marilyn J, Corbett, Dale, Corriveau, Roderick A, Cramer, Steven C, Ferguson, Adam R, Finklestein, Seth P, Ford, Byron D, Furie, Karen L, Hemmen, Thomas M, Iadecola, Costantino, Jakeman, Lyn B, Janis, Scott, Jauch, Edward C, Johnston, Karen C, Kochanek, Patrick M, Kohn, Harold, Lo, Eng H, Lyden, Patrick D, Mallard, Carina, McCullough, Louise D, McGavern, Linda M, Meschia, James F, Moy, Claudia S, Perez-Pinzon, Miguel A, Ramadan, Ipolia, Savitz, Sean I, Schwamm, Lee H, Steinberg, Gary K, Stenzel-Poore, Mary P, Tymianski, Michael, Warach, Steven, Wechsler, Lawrence R, Zhang, John H, and Koroshetz, Walter

Subjects
Animals, Humans, Disease Models, Animal, Chronic Disease, Thrombolytic Therapy, Thrombectomy, Age Factors, Comorbidity, Sex Factors, Recovery of Function, Research, Stroke, Translational Medical Research, animal model, biomarker, outcome, recovery, reperfusion, Neurology & Neurosurgery, Cardiorespiratory Medicine and Haematology, Clinical Sciences, Neurosciences
Published
2017

9. Biomarkers of Acute Stroke Etiology (BASE) Study Methodology.

Author

Jauch, Edward C, Barreto, Andrew D, Broderick, Joseph P, Char, Doug M, Cucchiara, Brett L, Devlin, Thomas G, Haddock, Alison J, Hicks, William J, Hiestand, Brian C, Jickling, Glen C, June, Jeff, Liebeskind, David S, Lowenkopf, Ted J, Miller, Joseph B, O'Neill, John, Schoonover, Tim L, Sharp, Frank R, and Peacock, W Frank

Subjects
Acute Stroke, Biomarkers, RNA expression, Clinical Sciences, Neurosciences, Public Health and Health Services
Abstract

Acute ischemic stroke affects over 800,000 US adults annually, with hundreds of thousands more experiencing a transient ischemic attack. Emergent evaluation, prompt acute treatment, and identification of stroke or TIA (transient ischemic attack) etiology for specific secondary prevention are critical for decreasing further morbidity and mortality of cerebrovascular disease. The Biomarkers of Acute Stroke Etiology (BASE) study is a multicenter observational study to identify serum markers defining the etiology of acute ischemic stroke. Observational trial of patients presenting to the hospital within 24 h of stroke onset. Blood samples are collected at arrival, 24, and 48 h later, and RNA gene expression is utilized to identify stroke etiology marker candidates. The BASE study began January 2014. At the time of writing, there are 22 recruiting sites. Enrollment is ongoing, expected to hit 1000 patients by March 2017. The BASE study could potentially aid in focusing the initial diagnostic evaluation to determine stroke etiology, with more rapidly initiated targeted evaluations and secondary prevention strategies.Clinical Trial Registration Clinicaltrials.gov NCT02014896 https://clinicaltrials.gov/ct2/show/NCT02014896?term=biomarkers+of+acute+stroke+etiology&rank=1.

Published
2017

12. Abstract TP110: Strengthening Neurology and Cardiology Care Collaboration: Getting to the Heart of Stroke Initiative

Author

Olson, Liz, primary, Leesch, Tharen, additional, Congdon, Michelle, additional, Manoukian, Steven V, additional, Schneider, Alexander T, additional, Canby, Robert, additional, Bailey, Alison, additional, Moody, Ashley, additional, Harper, Russell, additional, Orndorff, Kevin, additional, Stergar, Lindsay, additional, and Jauch, Edward C, additional

Published
2024
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16. Guidelines for the primary prevention of stroke: a statement for healthcare professionals from the American Heart Association/American Stroke Association.

Author

Meschia, James, Bushnell, Cheryl, Boden-Albala, Bernadette, Braun, Lynne, Bravata, Dawn, Chaturvedi, Seemant, Creager, Mark, Eckel, Robert, Elkind, Mitchell, Fornage, Myriam, Goldstein, Larry, Greenberg, Steven, Horvath, Susanna, Iadecola, Costantino, Jauch, Edward, Moore, Wesley, and Wilson, John

Subjects
AHA Scientific Statements, atrial fibrillation, diabetes mellitus, hyperlipidemias, hypertension, intracranial aneurysm, ischemia, prevention and control, smoking, stroke, American Heart Association, Evidence-Based Medicine, Humans, Primary Prevention, Risk Factors, Stroke, United States
Abstract

The aim of this updated statement is to provide comprehensive and timely evidence-based recommendations on the prevention of stroke among individuals who have not previously experienced a stroke or transient ischemic attack. Evidence-based recommendations are included for the control of risk factors, interventional approaches to atherosclerotic disease of the cervicocephalic circulation, and antithrombotic treatments for preventing thrombotic and thromboembolic stroke. Further recommendations are provided for genetic and pharmacogenetic testing and for the prevention of stroke in a variety of other specific circumstances, including sickle cell disease and patent foramen ovale.

Published
2014

18. Common Data Element for Unruptured Intracranial Aneurysm and Subarachnoid Hemorrhage: Recommendations from Assessments and Clinical Examination Workgroup/Subcommittee

Author

Damani, Rahul, Mayer, Stephan, Dhar, Raj, Martin, Renee H., Nyquist, Paul, Olson, DaiWai M., Mejia-Mantilla, Jorge H., Muehlschlegel, Susanne, Jauch, Edward C., Mocco, J., Mutoh, Tatsushi, Suarez, Jose I., and the Unruptured Intracranial Aneurysms and SAH CDE Project Investigators

Published
2019
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23. Clinical Performance Measures for Emergency Department Care for Adults With Intracranial Hemorrhage

Author

Zachrison, Kori S., primary, Goldstein, Joshua N., additional, Jauch, Edward, additional, Radecki, Ryan P., additional, Madsen, Tracy E., additional, Adeoye, Opeolu, additional, Oostema, John A., additional, Feeser, V. Ramana, additional, Ganti, Latha, additional, Lo, Bruce M., additional, Meurer, William, additional, Corral, Mitra, additional, Rothenberg, Craig, additional, Chaturvedi, Anshita, additional, Goyal, Pawan, additional, and Venkatesh, Arjun K., additional

Published
2023
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29. Abstract WP49: Clinical Performance Measures For Emergency Department Care For Adults With Nontraumatic Intracranial Hemorrhage

Author

Zachrison, Kori S, primary, Goldstein, Joshua N, additional, Jauch, Edward C, additional, Radecki, Ryan, additional, Madsen, Tracy, additional, Adeoye, Opeolu M, additional, Oostema, John A, additional, Feeser, Ramana, additional, Ganti, Latha, additional, Lo, Bruce M, additional, Meurer, William J, additional, Garvin, Rachel, additional, Corral, Mitra, additional, Rothenberg, Craig, additional, Mendez-Hernandez, Cindy, additional, Finch, Melissa, additional, Goyal, Pawan, additional, and Venkatesh, Arjun, additional

Published
2023
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30. Abstract WP38: Variation In Performance On Stroke Care Delivery Measures Among Us Community Emergency Departments

Author

Zachrison, Kori S, primary, Rothenberg, Craig, additional, Adeoye, Opeolu M, additional, Feeser, V. Ramana, additional, Ganti, Latha, additional, Goldstein, Joshua N, additional, Jauch, Edward C, additional, Lo, Bruce, additional, Madsen, Tracy, additional, Corral, Mitra, additional, Decker-Palmer, Marquita, additional, Mendez-Hernandez, Cindy, additional, Finch, Melissa, additional, Goyal, Pawan, additional, and Venkatesh, Arjun, additional

Published
2023
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33. 2018 Guidelines for the Early Management of Patients With Acute Ischemic Stroke: A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association

Author

Powers, William J., Rabinstein, Alejandro A., Ackerson, Teri, Adeoye, Opeolu M., Bambakidis, Nicholas C., Becker, Kyra, Biller, José, Brown, Michael, Demaerschalk, Bart M., Hoh, Brian, Jauch, Edward C., Kidwell, Chelsea S., Leslie-Mazwi, Thabele M., Ovbiagele, Bruce, Scott, Phillip A., Sheth, Kevin N., Southerland, Andrew M., Summers, Deborah V., and Tirschwell, David L.

Published
2018
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34. A survey of stroke‐related capabilities among a sample of US community emergency departments

Author

Zachrison, Kori S., primary, Ganti, Latha, additional, Sharma, Dhruv, additional, Goyal, Pawan, additional, Decker‐Palmer, Marquita, additional, Adeoye, Opeolu, additional, Goldstein, Joshua N., additional, Jauch, Edward C., additional, Lo, Bruce M., additional, Madsen, Tracy E., additional, Meurer, William, additional, Oostema, John A., additional, Mendez‐Hernandez, Cindy, additional, and Venkatesh, Arjun K., additional

Published
2022
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38. Common Data Elements for Radiological Imaging of Patients with Subarachnoid Hemorrhage: Proposal of a Multidisciplinary Research Group

Author

Hackenberg, Katharina A. M., Etminan, Nima, Wintermark, Max, Meyers, Philip M., Lanzino, Giuseppe, Rüfenacht, Daniel, Krings, Timo, Huston, John, Rinkel, Gabriel, Derdeyn, Colin, Suarez, Jose I., Macdonald, R. Loch, Amin-Hanjani, Sepideh, Brown, Robert D., de Oliveira Manoel, Airton Leonardo, Derdeyn, Colin P., Keller, Emanuela, LeRoux, Peter D., Mayer, Stephan, Morita, Akio, Rufennacht, Daniel, Stienen, Martin N., Torner, James, Vergouwen, Mervyn D. I., Wong, George K. C., Bijlenga, Philippe, Ko, Nerissa, McDougall, Cameron G., Mocco, J., Murayama, Yuuichi, Werner, Marieke J. H., Damani, Rahul, Broderick, Joseph, Dhar, Raj, Jauch, Edward C., Kirkpatrick, Peter J., Martin, Renee H., Muehlschlegel, Susanne, Mutoh, Tatsushi, Nyquist, Paul, Olson, Daiwai, Mejia-Mantilla, Jorge H., van der Jagt, Mathieu, Bambakidis, Nicholas, Brophy, Gretchen, Bulsara, Ketan, Claassen, Jan, Sander Connolly, E., Roos, Y. B., Moy, Claudia, Esterlitz, Joy, Joseph, Kristen, Sheikh, Muniza, Neurology, Experimental Vascular Medicine, ANS - Amsterdam Neuroscience, ACS - Atherosclerosis & ischemic syndromes, and ANS - Neurovascular Disorders

Subjects
Biomedical Research, Computed Tomography Angiography, Ultrasonography, Doppler, Transcranial, Perfusion scanning, Aneurysm, Ruptured, Critical Care and Intensive Care Medicine, Imaging, 0302 clinical medicine, Data standardization, Unruptured intracranial aneurysms, Non-U.S. Gov't, Stroke, Neuroradiology, Common Data Elements, medicine.diagnostic_test, Research Support, Non-U.S. Gov't, Magnetic Resonance Imaging, Radiology, medicine.medical_specialty, Subarachnoid hemorrhage, Perfusion Imaging, Digital subtraction angiography, Clinical Neurology, Research Support, N.I.H, 03 medical and health sciences, Aneurysm, Journal Article, medicine, Humans, National Institute of Neurological Disorders and Stroke (U.S.), cardiovascular diseases, Intramural, National Library of Medicine (U.S.), business.industry, Angiography, Digital Subtraction, 030208 emergency & critical care medicine, Intracranial Aneurysm, Subarachnoid Hemorrhage, Research Support, N.I.H., Intramural, medicine.disease, United States, Transcranial Doppler, Cerebral Angiography, Angiography, Neurology (clinical), business, Tomography, X-Ray Computed, 030217 neurology & neurosurgery, Magnetic Resonance Angiography
Abstract

Introduction: Lack of homogeneous definitions for imaging data and consensus on their relevance in the setting of subarachnoid hemorrhage and unruptured intracranial aneurysms lead to a difficulty of data pooling and lack of robust data. The aim of the National Institute of Health/National Institute of Neurological Disorders and Stroke, Unruptured Intracranial Aneurysm (UIA) and Subarachnoid Hemorrhage (SAH) Common Data Elements (CDE) Project was to standardize data elements to ultimately facilitate data pooling and establish a more robust data quality in future neurovascular research on UIA and SAH. Methods: For the subcommittee ‘Radiological imaging of SAH,’ international cerebrovascular specialists with imaging expertise in the setting of SAH were selected by the steering committee. CDEs were developed after reviewing the literature on neuroradiology and already existing CDEs for other neurological diseases. For prioritization, the CDEs were classified into ‘Core,’ ‘Supplemental—Highly Recommended,’ ‘Supplemental’ and ‘Exploratory.’ Results: The subcommittee compiled 136 CDEs, 100 out of which were derived from previously established CDEs on ischemic stroke and 36 were newly created. The CDEs were assigned to four main categories (several CDEs were assigned to more than one category): ‘Parenchymal imaging’ with 42 CDEs, ‘Angiography’ with 49 CDEs, ‘Perfusion imaging’ with 20 CDEs, and ‘Transcranial doppler’ with 55 CDEs. The CDEs were classified into core, supplemental highly recommended, supplemental and exploratory elements. The core CDEs were imaging modality, imaging modality type, imaging modality vessel, angiography type, vessel angiography arterial anatomic site and imaging vessel angiography arterial result. Conclusions: The CDEs were established based on the current literature and consensus across cerebrovascular specialists. The use of these CDEs will facilitate standardization and aggregation of imaging data in the setting of SAH. However, the CDEs may require reevaluation and periodic adjustment based on current research and improved imaging quality and novel modalities.

Published
2019

39. Definition and Prioritization of Data Elements for Cohort Studies and Clinical Trials on Patients with Unruptured Intracranial Aneurysms: Proposal of a Multidisciplinary Research Group

Author

Hackenberg, Katharina A. M., Algra, Ale, Salman, Rustam Al-Shahi, Frösen, Juhana, Hasan, David, Juvela, Seppo, Langer, David, Meyers, Philip, Morita, Akio, Rinkel, Gabriel, Etminan, Nima, Suarez, Jose I., Macdonald, R. Loch, Amin-Hanjani, Sepideh, Brown, Robert D., de Oliveira Manoel, Airton Leonardo, Derdeyn, Colin P., Keller, Emanuela, LeRoux, Peter D., Mayer, Stephan, Rufennacht, Daniel, Stienen, Martin N., Torner, James, Vergouwen, Mervyn D. I., Wong, George K. C., Bijlenga, Philippe, Ko, Nerissa, McDougall, Cameron G., Mocco, J., Murayama, Yuuichi, Werner, Marieke J. H., Damani, Rahul, Broderick, Joseph, Dhar, Raj, Jauch, Edward C., Kirkpatrick, Peter J., Martin, Renee H., Muehlschlegel, Susanne, Mutoh, Tatsushi, Nyquist, Paul, Olson, Daiwai, Mejia-Mantilla, Jorge H., van der Jagt, Mathieu, Bambakidis, Nicholas, Brophy, Gretchen, Bulsara, Ketan, Claassen, Jan, Connolly, E. Sander, Hoffer, S. Alan, Roos, Y. B., Siddiqui, A., Ala’i, Sherita, Esterlitz, Joy, Sheikh, M., Experimental Vascular Medicine, ANS - Amsterdam Neuroscience, Neurology, ACS - Atherosclerosis & ischemic syndromes, ANS - Neurovascular Disorders, and University of Helsinki, Department of Neurosciences

Subjects
Morphology, Prioritization, medicine.medical_specialty, Biomedical Research, PREDICTION, Clinical Neurology, MEDLINE, ENLARGEMENT, RUPTURE RISK, FREQUENCY, Critical Care and Intensive Care Medicine, 3124 Neurology and psychiatry, Cohort Studies, 03 medical and health sciences, 0302 clinical medicine, Data standardization, Unruptured intracranial aneurysms, Multidisciplinary approach, medicine, Humans, National Institute of Neurological Disorders and Stroke (U.S.), Stroke, SUBARACHNOID HEMORRHAGE, Clinical Trials as Topic, Aneurysm morphology, Common Data Elements, National Library of Medicine (U.S.), business.industry, 3112 Neurosciences, Intracranial Aneurysm, 030208 emergency & critical care medicine, NATURAL-HISTORY, CEREBRAL ANEURYSMS, 3126 Surgery, anesthesiology, intensive care, radiology, medicine.disease, United States, 3. Good health, Clinical trial, SIZE, Risk factors, Emergency medicine, RISK-FACTORS, GROWTH, Neurology (clinical), Neurosurgery, business, 030217 neurology & neurosurgery, Cohort study
Abstract

Introduction: Variability in usage and definition of data characteristics in previous cohort studies on unruptured intracranial aneurysms (UIA) complicated pooling and proper interpretation of these data. The aim of the National Institute of Health/National Institute of Neurological Disorders and Stroke UIA and Subarachnoid Hemorrhage (SAH) Common Data Elements (CDE) Project was to provide a common structure for data collection in future research on UIA and SAH. Methods: This paper describes the development and summarization of the recommendations of the working groups (WGs) on UIAs, which consisted of an international and multidisciplinary panel of cerebrovascular specialists on research and treatment of UIAs. Consensus recommendations were developed by review of previously published CDEs for other neurological diseases and the literature on UIAs. Recommendations for CDEs were classified by priority into ‘Core,’ ‘Supplemental—Highly Recommended,’ ‘Supplemental,’ and ‘Exploratory.’ Results: Ninety-one CDEs were compiled; 69 were newly created and 22 were existing CDEs. The CDEs were assigned to eight subcategories and were classified as Core (8), Supplemental—Highly Recommended (23), Supplemental (25), and Exploratory (35) elements. Additionally, the WG developed and agreed on a classification for aneurysm morphology. Conclusion: The proposed CDEs have been distilled from a broad pool of characteristics, measures, or outcomes. The usage of these CDEs will facilitate pooling of data from cohort studies or clinical trials on patients with UIAs.

Published
2019
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40. Endovascular Therapy Is Effective and Safe for Patients With Severe Ischemic Stroke: Pooled Analysis of Interventional Management of Stroke III and Multicenter Randomized Clinical Trial of Endovascular Therapy for Acute Ischemic Stroke in the Netherlands Data

Author

Broderick, Joseph P., Berkhemer, Olvert A., Palesch, Yuko Y., Dippel, Diederik W.J., Foster, Lydia D., Roos, Yvo B.W.E.M., van der Lugt, Aad, Tomsick, Thomas A., Majoie, Charles B.L.M., van Zwam, Wim H., Demchuk, Andrew M., van Oostenbrugge, Robert J., Khatri, Pooja, Lingsma, Hester F., Hill, Michael D., Roozenbeek, Bob, Jauch, Edward C., Jovin, Tudor G., Yan, Bernard, von Kummer, Rüdiger, Molina, Carlos A., Goyal, Mayank, Schonewille, Wouter J., Mazighi, Mikael, Engelter, Stefan T., Anderson, Craig S., Spilker, Judith, Carrozzella, Janice, Ryckborst, Karla J., Janis, L. Scott, and Simpson, Kit N.

Published
2015
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41. 2015 American Heart Association/American Stroke Association Focused Update of the 2013 Guidelines for the Early Management of Patients With Acute Ischemic Stroke Regarding Endovascular Treatment: A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association

Author

Powers, William J., Derdeyn, Colin P., Biller, José, Coffey, Christopher S., Hoh, Brian L., Jauch, Edward C., Johnston, Karen C., Johnston, S. Claiborne, Khalessi, Alexander A., Kidwell, Chelsea S., Meschia, James F., Ovbiagele, Bruce, and Yavagal, Dileep R.

Published
2015
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42. A collaborative sequential meta-analysis of individual patient data from randomized trials of endovascular therapy and tPA vs. tPA alone for acute ischemic stroke: ThRombEctomy And tPA (TREAT) analysis: statistical analysis plan for a sequential meta-analysis performed within the VISTA-Endovascular collaboration

Author

MacIsaac, Rachael L., Khatri, Pooja, Bendszus, Martin, Bracard, Serge, Broderick, Joseph, Campbell, Bruce, Ciccone, Alfonso, Dávalos, Antoni, Davis, Stephen M., Demchuk, Andrew, Diener, Hans-Christoph, Dippel, Diederik, Donnan, Geoffrey A., Fiehler, Jens, Fiorella, David, Goyal, Mayank, Hacke, Werner, Hill, Michael D., Jahan, Reza, Jauch, Edward, Jovin, Tudor, Kidwell, Chelsea S., Liebeskind, David, Majoie, Charles B., Martins, Sheila Cristina Ouriques, Mitchell, Peter, Mocco, J., Muir, Keith W., Nogueira, Raul, Saver, Jeffrey L., Schonewille, Wouter J., Siddiqui, Adnan H., Thomalla, Götz, Tomsick, Thomas A., Turk, Aquilla S., White, Philip, Zaidat, Osama, and Lees, Kennedy R.

Published
2015
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46. State of Acute Endovascular Therapy: Report From the 12th Thrombolysis, Thrombectomy, and Acute Stroke Therapy Conference

Author

Khatri, Pooja, Hacke, Werner, Fiehler, Jens, Saver, Jeffrey L., Diener, Hans-Christoph, Bendszus, Martin, Bracard, Serge, Broderick, Joseph, Campbell, Bruce, Ciccone, Alfonso, Dávalos, Antoni, Davis, Stephen, Demchuk, Andrew M., Dippel, Diederik, Donnan, Geoffrey, Fiorella, David, Goyal, Mayank, Hill, Michael D., Jauch, Edward C., Jovin, Tudor G., Kidwell, Chelsea S., Majoie, Charles, Martins, Sheila Cristina Ouriques, Mitchell, Peter, Mocco, J, Muir, Keith, Nogueira, Raul G., Schonewille, Wouter J., Siddiqui, Adnan H., Thomalla, Götz, Tomsick, Thomas A., Turk, Aquilla S., White, Philip M., Zaidat, Osama O., Liebeskind, David S., Fulton, Rachel, and Lees, Kennedy R.

Published
2015
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47. Twelve-Month Clinical and Quality-of-Life Outcomes in the Interventional Management of Stroke III Trial

Author

Palesch, Yuko Y., Yeatts, Sharon D., Tomsick, Thomas A., Foster, Lydia D., Demchuk, Andrew M., Khatri, Pooja, Hill, Michael D., Jauch, Edward C., Jovin, Tudor G., Yan, Bernard, von Kummer, Rüdiger, Molina, Carlos A., Goyal, Mayank, Schonewille, Wouter J., Mazighi, Mikael, Engelter, Stefan T., Anderson, Craig, Spilker, Judith, Carrozzella, Janice, Ryckborst, Karla J., Janis, L. Scott, Simpson, Annie, Simpson, Kit N., and Broderick, Joseph P.

Published
2015
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48. Correction to: Definition and Prioritization of Data Elements for Cohort Studies and Clinical Trials on Patients with Unruptured Intracranial Aneurysms: Proposal of a Multidisciplinary Research Group (Neurocritical Care, (2019), 30, S1, (87-101), 10.1007/s12028-019-00729-0)

Author

Hackenberg, Katharina A. M., Algra, Ale, Al‑Shahi Salman, Rustam, Frösen, Juhana, Hasan, David, Juvela, Seppo, Langer, David, Meyers, Philip, Morita, Akio, Rinkel, Gabriel, Etminan, Nima, Suarez, Jose I., Macdonald, R. Loch, Amin-Hanjani, Sepideh, Brown, Robert D., de Oliveira Manoel, Airton Leonardo, Derdeyn, Colin P., Keller, Emanuela, LeRoux, Peter D., Mayer, Stephan, Rufennacht, Daniel, Stienen, Martin N., Torner, James, Vergouwen, Mervyn D. I., Wong, George K. C., Bijlenga, Philippe, Ko, Nerissa, McDougall, Cameron G., Mocco, J., Murayama, Yuuichi, Werner, Marieke J. H., Damani, Rahul, Broderick, Joseph, Dhar, Raj, Jauch, Edward C., Kirkpatrick, Peter J., Martin, Renee H., Muehlschlegel, Susanne, Mutoh, Tatsushi, Nyquist, Paul, Olson, Daiwai, Mejia-Mantilla, Jorge H., van der Jagt, Mathieu, Bambakidis, Nicholas, Brophy, Gretchen, Bulsara, Ketan, Claassen, Jan, Connolly, E. Sander, Hoffer, S. Alan, Roos, Y. B., Neurology, ACS - Atherosclerosis & ischemic syndromes, and Amsterdam Neuroscience - Neurovascular Disorders

Abstract

This article was updated to correct the tagging of Rustam Al-Shahi Salman in the article metadata

Published
2021

49. Evolution of Practice During the Interventional Management of Stroke III Trial and Implications for Ongoing Trials

Author

Broderick, Joseph P., Palesch, Yuko Y., Demchuk, Andrew M., Yeatts, Sharon D., Khatri, Pooja, Hill, Michael D., Jauch, Edward C., Jovin, Tudor G., Yan, Bernard, von Kummer, Rüdiger, Molina, Carlos A., Goyal, Mayank, Mazighi, Mikael, Schonewille, Wouter J., Engelter, Stefan T., Anderson, Craig, Spilker, Judith, Carrozzella, Janice, Janis, L. Scott, Foster, Lydia D., and Tomsick, Thomas A.

Published
2014
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