Search

Your search keyword '"Hu, Jian-Guo"' showing total 168 results
Start Over Author "Hu, Jian-Guo" Publication Year Range Last 10 years
168 results on '"Hu, Jian-Guo"'

7. IL-11 Plays a Protective Anti-Inflammatory Role in Spinal Cord Injury by Inhibiting Microglial Activation Through Suppression of ISG15 Signaling

Author

Sun, Yang, primary, Geng, Zhijun, additional, Xue, Song, additional, Xiao, Linyu, additional, Xu, Yibo, additional, Wang, Zhiyuan, additional, Liu, Xinyue, additional, Li, Jing, additional, Wang, Lian, additional, Wang, Yueyue, additional, Zhang, Xiaofeng, additional, Zuo, Lugen, additional, Lü, He-Zuo, additional, and Hu, Jian-Guo, additional

Published
2024
Full Text
View/download PDF

13. The polarization of microglia and infiltrated macrophages in the injured mice spinal cords: a dynamic analysis

Author

Li, Jing-Lu, primary, Fu, Gui-Qiang, additional, Wang, Yang-Yang, additional, Bian, Ming-Ming, additional, Xu, Yao-Mei, additional, Zhang, Lin, additional, Chen, Yu-Qing, additional, Zhang, Nan, additional, Ding, Shu-Qin, additional, Wang, Rui, additional, Fang, Rui, additional, Tang, Jie, additional, Hu, Jian-Guo, additional, and Lü, He-Zuo, additional

Published
2023
Full Text
View/download PDF

15. A 0.35mm2 94.25μ W Fully Integrated NFC Tag IC Using 0.13μ m CMOS Process

Author

Wang, De-Ming, Li, De-Zhi, Wu, Jing, Cai, Jian-Hao, Zhong, Qing-Hua, Huang, Xin, and Hu, Jian-Guo

Abstract

An NFC tag chip employing the ISO/IEC14443-A protocol is developed in SMIC $0.13\mu \text{m}$ EEPROM 2P6M CMOS process, boasting a chip area of $620.03\mu \text{m}\times 567.93\mu \text{m}$ and a power consumption of under $100\mu \text{W}$ . The chip addresses critical issues such as reducing power consumption and minimizing area costs for covering numerous IoT nodes. For a small area of the chip, a specialized ESD protection circuit is proposed, efficiently multiplexing discharge transistors, cross-gate connected rectifiers, limiters for overvoltage protection, and load switch modulators within the chip’s limited space. For power efficiency, a compact $175.44\mu \text{m}\times 32.98\mu \text{m}\,\,18.52\mu \text{A}$ LDO based on the current mirror and current feedback is presented for the DC supply during the 100% ASK modulation. Additionally, an ASK demodulator and a 13.56MHz±kHz clock generator are designed in compact areas of $62.19\mu \text{m}\times 56.06\mu \text{m}$ and $24.76\mu \text{m}\times 13.14\mu \text{m}$ , respectively. These components ensure stable protocol communication with digital circuits and support a 7kb EEPROM, providing a comprehensive solution for NFC-based IoT information collection.

Published
2024
Full Text
View/download PDF

16. CD36-mediated podocyte lipotoxicity promotes foot process effacement

Author

Hua, Wei, primary, Peng, Lan, additional, Chen, Xue-mei, additional, Jiang, Xu-Shun, additional, Hu, Jian-Guo, additional, Jiang, Xian-Hong, additional, Xiang, Xu, additional, Wan, Jiang-min, additional, Long, Yingfei, additional, Xiong, Jian-qiong, additional, ma, Xueyi, additional, and Du, Xiao-gang, additional

Published
2023
Full Text
View/download PDF

17. Reconfigurable Pb-Free Perovskite Array for X-Ray In-Sensor Computing

Author

Dun, Guan-Hua, primary, Qin, Ken, additional, Zhang, Hai-Nan, additional, Feng, Qi-Xin, additional, Wang, Ze-Shu, additional, Geng, Xiang-Shun, additional, Li, Yuan-Yuan, additional, Wan, Peng, additional, He, Yi-Chu, additional, Hu, Jian-Guo, additional, Peng, Jia-Li, additional, Liang, Ren-Rong, additional, Xie, Dan, additional, Tian, He, additional, Yang, Yi, additional, and Ren, Tian-Ling, additional

Published
2023
Full Text
View/download PDF

28. Theoretical investigations on the defect structures and g factors for V4+ in 30PbO‐5Bi2O3‐(65‐x)SiO2 glasses at different concentrations.

Author

Hu, Jian‐Guo, Wu, Shao‐Yi, Yan, Li, Wei, Zhang‐Ting, Yang, Yi, Wu, Hao, and Zhu, Qin‐Sheng

Subjects
*FACTOR structure, *DIELECTRIC relaxation, *CONCENTRATION functions, *ELECTRON distribution, *ELECTRIC conductivity, *GLASS
Abstract

For 3d1 (V4+) impurity in 30PbO‐5Bi2O3‐(65‐x)SiO2 glass systems with different concentrations x of V2O5, the defect structures and gyromagnetic factors are theoretically investigated by using the perturbation formulas of g factors for a tetragonally compressed octahedral 3d1 group. The concentration dependences of d‐d transition band and g factors are suitably explained from the Fourier type concentration functions of the cubic crystal field parameter Dq, covalency factor N and relative tetragonal compression ratio ρ. The above concentration dependences of these quantities are suitably illustrated by the modifications of the local crystal field strength and electron cloud distribution with increasing x. The concentration variations of the electrical conductivity and dielectric relaxation are further analyzed from the stability of the systems in view of two competitive factors (increasing network polymerization and bulk stability at low concentrations and decreasing former SiO2 and stability at high concentrations). [ABSTRACT FROM AUTHOR]

Published
2022
Full Text
View/download PDF

30. Feature article: Neuroprotective effects of P7C3 against spinal cord injury in rats

Author

Duan, Fei-Xiang, Shi, Yu-Jiao, Chen, Jing, Ding, Shu-Qin, Wang, Feng-Chao, Tang, Jie, Wang, Rui, Shen, Lin, Xi, Jin, Qi, Qi, Lü, He-Zuo, and Hu, Jian-Guo

Subjects
Neurons, Rats, Sprague-Dawley, Oligodendroglia, Neuroprotective Agents, Spinal Cord, Carbazoles, Animals, Female, Motor Activity, NAD, Spinal Cord Injuries, Original Research, Rats
Abstract

Spinal cord injury (SCI), a serious neurological disease, has few therapeutic interventions. A small molecule, P7C3, has been confirmed to play a role in neuroprotection of some neurological diseases. But the effect of P7C3 on acute SCI has not been investigated. Here, we observed the therapeutic effect of P7C3 for alleviating the neurological damage by direct subcutaneous injection after SCI once daily for 7 or 14 days in a rat model. The locomotion and histopathological changes were evaluated. Our results demonstrated that P7C3 treatment contributed to functional recovery and tissue repair following SCI. Improved locomotor function with P7C3 treatment was correlated with increased survival of neurons and oligodendrocytes (OLs) and proliferation of OLs and their progenitors, which resulted in tissue repair and myelination in the injured SC. P7C3 treatment also restored the nicotinamide adenine dinucleotide level in the SC, which was reduced by SCI. These results suggest that P7C3 plays a role in improving neurological outcome following SCI. IMPACT STATEMENT: Spinal cord injury (SCI), a serious neurological disease, has few therapeutic interventions. This study confirms for the first time that P7C3 is conducive to functional recovery and tissue repair after SCI. P7C3 treatment can rescue the nicotinamide adenine dinucleotide level of the injured spinal cord, which results in more survival of neurons and oligodendrocytes (OLs) and proliferation of OLs and their progenitors, and thus increase myelination and tissue repair. This result indicates that P7C3 plays a role in improving neurological outcome following SCI.

Published
2019

39. Neuroprotective effects of P7C3 against spinal cord injury in rats

Author

Duan, Fei-Xiang, primary, Shi, Yu-Jiao, additional, Chen, Jing, additional, Ding, Shu-Qin, additional, Wang, Feng-Chao, additional, Tang, Jie, additional, Wang, Rui, additional, Shen, Lin, additional, Xi, Jin, additional, Qi, Qi, additional, Lü, He-Zuo, additional, and Hu, Jian-Guo, additional

Published
2019
Full Text
View/download PDF

40. ANTI-INFLAMMATORY ACTIVITY OF PLATYCODIN D ON ALCOHOL-INDUCED FATTY LIVER RATS VIA TLR4-MYD88-NF-κB SIGNAL PATH

Author

Wu, Jing-tao, Yang, Gui-wen, Qi, Cui-hua, Zhou, Lei, Hu, Jian-guo, and Wang, Mao-shan

Subjects
Male, Platycodon, Interleukin-6, Tumor Necrosis Factor-alpha, toll-like receptor 4, Anti-Inflammatory Agents, NF-kappa B, Saponins, Plant Roots, Article, anti-inflammation, Triterpenes, Rats, Fatty Liver, Alcohols, Animals, Humans, Platycodin D, alcoholic, Drugs, Chinese Herbal, Signal Transduction
Abstract

Background: The current study was designed to evaluate the effect of Platycodin D (PD), triterpenoid saponins extracted from the roots of Platycodon grandiflorum (PG) on alcohol-induced fatty liver (AFL) and investigate the possible mechanism. Methods and Materials: A rat model was set up by feeding ethanol and fish oil to experimental rats, which then were treated with PD of 10, 20, 30 mg/kg body weight/day for 4 weeks, respectively, whereafter, liver function enzymes, endotoxin of serum and liver lipid were assayed by biochemical methods, cytokines, histochemistry of hepatic tissue, the protein expression of CD14 and TLR4, the mRNA expression of MD-2, MyD 88 and TRAF-6 were assayed. Results: Treatment with PD on AFL rats significantly decreased the levels of serum ALT, AST and TBIL, coefficient of liver index and the hepatic tissue contents of TG, additionally and dramatically decreased serum endotoxin levels, down-regulated MD-2 and CD14 levels, as well as the mRNA expression of TLR4, MyD88 and TRAF-6, accordingly suppressed NF-κB: p65 as well as endotoxin-mediated inflammatory factors such as TNF-α and IL-6. Conclusions: Treatment with PD effectively protects against AFL through anti-inflammatory and anti-endotoxic process, and the confirmed mechanism is that PD treatment ameliorate alcoholic-induced liver injury mainly via TLR4-MyD88-NF-K: B signal path in AFL rat. List of Abbreviations: AFL: alcoholic-induced fatty liver, CD14: cluster of differentiation 14, LPS: lipopolysaccharide, LBP: lipopolysaccharide-binding protein, TLR4: toll-like receptor 4, MD-2: molecule myeloid differential protein-2, MyD 88: myeloid differentiation primary response protein 88, TRAF-6: TNF-receptor associated factor-6, NF-κB: nuclear transcription factor kappa B, IL-6: interleukin-6, TNF-α: tumor necrosis factor-α, PG: Platycodon grandiflorum, PD: Platycodin D.

Published
2016

Catalog

Books, media, physical & digital resources
See catalog results