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Your search keyword '"Hong, Seung Beom"' showing total 330 results
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330 results on '"Hong, Seung Beom"'

6. Re-identification of Strains from Aspergillus Section Aspergillus and Description of Three Unrecorded Species from Korea.

Author

Mageswari, Anbazhagan, Lee, Daseul, Thao, Le Dinh, Kang, Donghun, Kim, Dong-Hyun, and Hong, Seung-Beom

Abstract

The section Aspergillus includes xerophilic fungi that are economically significant and broadly distributed in natural settings as well as human habitats and are recognized for their sustenance on substrates with low water activity. Accurate identification of fungal species is essential for any reliable advances in mycological research. In this study, 108 strains from the section Aspergillus, originating from Korea and conserved at the Korean Agricultural Culture Collection, were subjected to re-identification using a combined dataset that included partial sequences of β-tubulin (BenA), Calmodulin (CaM), and RNA polymerase II second largest subunit (RPB2) genes, along with their morphological characteristics. We confirmed the presence of 12 species among the 108 strains originally isolated from Korea. Of them, nine species have been formerly reported in Korea (Aspergillus chevalieri, Aspergillus cibarius, Aspergillus cumulatus, Aspergillus glaucus, Aspergillus montevidensis, Aspergillus proliferans, Aspergillus pseudoglaucus, Aspergillus ruber, and Aspergillus tonophilus), and 3 species (Aspergillus aurantiacoflavus, Aspergillus intermedius, and Aspergillus niveoglaucus) were found to be previously unreported to be isolated from Korea. Here, the detailed characteristic features of these three unexplored species are presented, including specific morphological traits, genetic variations, and ecological niches in Korea. [ABSTRACT FROM AUTHOR]

Published
2024
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13. Strengthening the Korean Network of Microbial Culture Collections in the Microbiome Era.

Author

Kim, Yiseul, Cheong, Hyang Min, Choi, Grace, Choi, Kyung-Min, Chung, Eu Jin, Kim, Ahran, Kim, Song-Gun, Kim, Soonok, Lee, Jung-Sook, Yang, Dong-Kun, and Hong, Seung-Beom

Subjects
MICROBIAL cultures, BACTERIAL inactivation, INTERNATIONAL organization, WORLD culture, CELL lines
Abstract

Microbes are critical contributors in main areas of biotechnology, including green, red, and white biotechnology. This is why the importance of the preservation of microbial resources cannot be emphasized enough. Culture collections are repositories not only for the preservation and maintenance of a large variety of microbial resources and the associated data but also for their distribution in a quality-controlled manner. The mission of culture collections facilitates and supports utilization of microbial resources for research, education, and industrial purposes. Led by the World Federation for Culture Collections, an international organization committed to fostering the activities of culture collections of microorganisms and cell lines, more than 850 culture collections from 80 countries and regions work together to ensure the perpetuation of microbial resources. In addition, domestic networks, such as Japan Society for Culture Collections and United States Culture Collection Network along with regional networks for Europe, Latin America, and Asia thrive to ensure the long-term viability of microbial resources. The Republic of Korea recently took the first step in networking through the coordination of six ministries which house nine national microbial culture collections. With an explosion in microbiome research and a dramatic increase in the number of microbiome samples, the considerable challenge of culture collections will therefore be implementing the biobanking infrastructure of microbiome samples. Creating a domestic network of national culture collections is a key factor in efficiently and comprehensively managing nation-led microbiome research projects, particularly resulting microbiome samples. In this context, this review aims to provide an overview of microbial culture collection network and their future role to address the challenge in the microbiome era. [ABSTRACT FROM AUTHOR]

Published
2024
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19. Introduction of List of Plant Diseases in Korea 6.1st Edition (2023 Revised Version)

Author

Kim, Seon-Hee, primary, Choi, Jaehyuk, additional, Choi, Young-Joon, additional, Park, Byeong-Yong, additional, Lee, Su-Heon, additional, Kim, Gyoung Hee, additional, Kong, Hyun Gi, additional, Kim, Donggun, additional, Kim, Soonok, additional, Kim, Youngho, additional, Back, Chang-Gi, additional, Byun, Hee-Seong, additional, Seo, Jang Kyun, additional, Yu, Jun Myoung, additional, Yoon, Ju-Yeon, additional, Lee, Dong-Hyeon, additional, Lee, Seung-Yeol, additional, Lim, Seungmo, additional, Jeon, Yongho, additional, Chun, Jaeyong, additional, Choi, Insoo, additional, Choi, In-Young, additional, Choi, Hyo-Won, additional, Hong, Jin Sung, additional, and Hong, Seung-Beom, additional

Published
2023
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25. Five novel Hymenobacter species isolated from air: Hymenobacter cellulosilyticus sp. nov., Hymenobacter cellulosivorans sp. nov., Hymenobacter aerilatus sp. nov., Hymenobacter sublimis sp. nov. and Hymenobacter volaticus sp. nov.

Author

Kim, Yiseul, primary, Subramanian, Parthiban, additional, Choi, Hyorim, additional, Weon, Hang-Yeon, additional, Kim, Seunghwan, additional, Kwon, Soon-Wo, additional, Lee, Daseul, additional, Han, Byeong-Hak, additional, Hong, Seung-Beom, additional, and Heo, Jun, additional

Published
2023
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35. Supplementary Data from A Novel Therapeutic Anti-ErbB3, ISU104 Exhibits Potent Antitumorigenic Activity by Inhibiting Ligand Binding and ErbB3 Heterodimerization

Author

Hong, Mirim, primary, Yoo, Youngki, primary, Kim, Miyoung, primary, Kim, Ju Yeon, primary, Cha, Jeong Seok, primary, Choi, Myung Kyung, primary, Kim, Uijin, primary, Kim, Kyungyong, primary, Sohn, Youngsoo, primary, Bae, Donggoo, primary, Cho, Hyun-Soo, primary, and Hong, Seung-Beom, primary

Published
2023
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38. Re-Identification of AspergillusSubgenus NidulantesStrains and Description of Three Unrecorded Species From Korea

Author

Mageswari, Anbazhagan, Choi, Yunhee, Thao, Le Dinh, Lee, Daseul, Kim, Dong-Hyun, and Hong, Seung-Beom

Abstract

ABSTRACT:Aspergillussubgenus Nidulanteswith nine section forms the second largest subgenus of the fungi that comes under the genus Aspergillus.Species in this group of fungi are important as they are reported to play several important roles in the environment including influencing air quality in confined spaces, food spoilage, production of mycotoxins as well as in human pathogenicity. In the present study, 53 strains of Aspergillussubgenus Nidulantes(section: Nidulantes& Usti) isolated from Korea and preserved at the Korean Agricultural Culture Collection (KACC) were subjected to re-identification by using a combined dataset of partial β-tubulin (BenA), Calmodulin (CaM) gene sequences as well as their morphological data. We confirmed 14 species from 53 isolates in Korea. Of them, eleven species were reported in Korea previously (A. amoenus, A. baeticus, A. calidoustus, A. creber, A. insuetus, A. jensenii, A. nidulans, A. protuberus, A. sydowii, A. tabacinusand A. unguis), and three species (A. griseoaurantiacus, A. puulaauensisand A. sublatus) were previously unreported from Korea. We detailed the characteristic features of these three species, that remain unexplored in Korea.

Published
2024
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39. A phase Ia/Ib study of novel anti‐ErbB3 monoclonal antibody, barecetamab (ISU104) in refractory solid cancers and monotherapy or in combination with cetuximab in recurrent or metastatic head and neck cancer.

Author

Seo, Seyoung, Keam, Bhumsuk, Shin, Seong Hoon, Chae, Yee Soo, Kim, Tae Min, Park, Lee Chun, Hong, Seung‐Beom, Ahn, Myung‐Ju, and Kim, Sung‐Bae

Subjects
HEAD & neck cancer, CETUXIMAB, MONOCLONAL antibodies, DRUG side effects, CANCER patients
Abstract

We evaluated the safety, tolerability, pharmacokinetics and antitumor activity of barecetamab monotherapy and combination cetuximab therapy in patients with advanced solid cancers, especially head and neck cancer (HNC). Part 1 was a 3 + 3 dose‐escalation study in which 15 patients received barecetamab at 1, 3, 5, 10 and 20 mg/kg intravenously (IV) on days 1 and 28 and weekly in patients with advanced solid cancer. Part 2 was a dose‐expansion study including two patient groups with advanced HNC, including six patients receiving barecetamab at 20 mg/kg IV every 3 weeks and 12 patients receiving barecetamab and cetuximab (400 mg/m2 on day 1 followed by 250 mg/m2 every week). No dose‐limiting toxicities (DLTs) were observed. Maximum serum target engagement was reached with trough levels of doses ≥3 mg/kg IV weekly. Common adverse drug reactions were diarrhea, stomatitis, dermatitis acneiform and decreased appetite. One durable complete response of more than 17 months was observed, and the overall response and disease control rates were 36.4% (4/11) and 81.1% (9/11), respectively, in the combination therapy group. In conclusion, DLT was not observed in barecetamab at 1 to 20 mg/kg. The recommended phase II dose was determined to be 20 mg/kg triweekly. Barecetamab and in cetuximab combination was well tolerated and demonstrated meaningful antitumor effects. [ABSTRACT FROM AUTHOR]

Published
2023
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