149 results on '"Hoffmann, Jean-Sébastien"'
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2. Cytidine deaminase resolves replicative stress and protects pancreatic cancer from DNA-targeting drugs
3. Role of specialized DNA polymerases in the limitation of replicative stress and DNA damage transmission
4. High Expression of MRE11A Is Associated with Shorter Survival and a Higher Risk of Death in CRC Patients
5. High Expression of MRE11A, the Gene Involved in the Resection Step During Homologous Recombination, Is Associated with Shorter Survival and a Higher Risk of Death in CRC Patients
6. Chk1 loss creates replication barriers that compromise cell survival independently of excess origin firing
7. Overexpression of Claspin and Timeless protects cancer cells from replication stress in a checkpoint-independent manner
8. Exploring the basis of heterogeneity of cancer aggressiveness among the mutated POLE variants.
9. Supplementary Data from EMT Transcription Factor ZEB1 Represses the Mutagenic POLθ-Mediated End-Joining Pathway in Breast Cancers
10. Correction: Corrigendum: MUS81 nuclease activity is essential for replication stress tolerance and chromosome segregation in BRCA2-deficient cells
11. RIP140 regulates POLK gene expression and the response to alkylating drugs in colon cancer cells
12. A Truncated NRIP1 Mutant Amplifies Microsatellite Instability of Colorectal Cancer by Regulating MSH2/MSH6 Expression, and Is a Prognostic Marker of Stage III Tumors
13. Abstract PO-043: Cytidine deaminase protects pancreatic cancer cells from replicative stress and drive response to DNA-targeting drugs
14. Ciblage de l’ADN-polymérase θ en oncologie
15. A Catalytically Independent Function of Human DNA Polymerase Kappa Controls the Stability and Abundance of Checkpoint Kinase 1
16. Recent Advances in Enhancing the Therapeutic Index of PARP Inhibitors in Breast Cancer
17. Opposite Roles for ZEB1 and TMEJ in the Regulation of Breast Cancer Genome Stability
18. Depletion of DNA Polymerase Theta Inhibits Tumor Growth and Promotes Genome Instability through the cGAS-STING-ISG Pathway in Esophageal Squamous Cell Carcinoma
19. Analyzing the Opportunities to Target DNA Double-Strand Breaks Repair and Replicative Stress Responses to Improve Therapeutic Index of Colorectal Cancer
20. The Heritability of Replication Problems
21. Low Replicative Stress Triggers Cell-Type Specific Inheritable Advanced Replication Timing
22. Low replicative stress triggers cell-type specific inheritable advanced replication timing
23. Translesion Synthesis or Repair by Specialized DNA Polymerases Limits Excessive Genomic Instability upon Replication Stress
24. A Role for Human DNA Polymerase λ in Alternative Lengthening of Telomeres
25. A catalytic-independent function of human DNA polymerase Kappa controls the pool of the Checkpoint Kinase 1
26. EMT Transcription Factor ZEB1 Represses the Mutagenic POLθ-Mediated End-Joining Pathway in Breast Cancers
27. Dendrogenin A Enhances Anti-Leukemic Effect of Anthracycline in Acute Myeloid Leukemia
28. Under-Replicated DNA: The Byproduct of Large Genomes?
29. Low replication stress leads to specific replication timing advances associated to chromatin remodelling in cancer cells
30. A Catalytically Independent Function of Human DNA Polymerase Kappa Controls the Stability and Abundance of Checkpoint Kinase 1.
31. DNA polymerase ν gene expression influences fludarabine resistance in chronic lymphocytic leukemia independently from p53 status
32. When RAD52 Allows Mitosis to Accept Unscheduled DNA Synthesis
33. eIF4A inhibition circumvents uncontrolled DNA replication mediated by 4E-BP1 loss in pancreatic cancer
34. Excess Pol theta functions in response to replicative stress in homologous recombination-proficient cancer cells
35. The Protective Role of Dormant Origins in Response to Replicative Stress
36. DNA replication stress triggers rapid DNA replication fork breakage by Artemis and XPF
37. DNA polymerase ν gene expression influences fludarabine resistance in chronic lymphocytic leukemia independently of p53 status
38. Impact of the DNA polymerase Theta on the DNA replication program
39. Targeting ATR/CHK1 pathway in acute myeloid leukemia to overcome chemoresistance
40. MUS81 nuclease activity is essential for replication stress tolerance and chromosome segregation in BRCA2-deficient cells
41. Loss of 4E-BP1-mediated translational control favors DNA replication in pancreatic cancer.
42. Proper sister chromatid disjunction requires CDA and PARP-1
43. Proteomic Profiling Reveals a Specific Role for Translesion DNA Polymerase η in the Alternative Lengthening of Telomeres
44. Cyclin Kinase-independent role of p21CDKN1A in the promotion of nascent DNA elongation in unstressed cells
45. Author response: Cyclin Kinase-independent role of p21CDKN1A in the promotion of nascent DNA elongation in unstressed cells
46. Analysis of DNA Replication by Optical Mapping in Nanochannels
47. CHK1 as a therapeutic target to bypass chemoresistance in AML
48. Human Adipose-Derived Stem Cells Expanded Under Ambient Oxygen Concentration Accumulate Oxidative DNA Lesions and Experience Procarcinogenic DNA Replication Stress
49. Human Adipose-Derived Stem Cells Expanded Under Ambient Oxygen Concentration Accumulate Oxidative DNA Lesions and Experience Procarcinogenic DNA Replication Stress.
50. Cyclin Kinase-independent role of p21CDKN1A in the promotion of nascent DNA elongation in unstressed cell.
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