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2. Ancient mitogenomes from Pre-Pottery Neolithic Central Anatolia and the effects of a Late Neolithic bottleneck in sheep ( Ovis aries )

Author

Sandoval-Castellanos, Edson, primary, Hare, Andrew J., additional, Lin, Audrey T., additional, Dimopoulos, Evangelos A., additional, Daly, Kevin G., additional, Geiger, Sheila, additional, Mullin, Victoria E., additional, Wiechmann, Ingrid, additional, Mattiangeli, Valeria, additional, Lühken, Gesine, additional, Zinovieva, Natalia A., additional, Zidarov, Petar, additional, Çakırlar, Canan, additional, Stoddart, Simon, additional, Orton, David, additional, Bulatović, Jelena, additional, Mashkour, Marjan, additional, Sauer, Eberhard W., additional, Horwitz, Liora Kolska, additional, Horejs, Barbara, additional, Atici, Levent, additional, Özkaya, Vecihi, additional, Mullville, Jacqui, additional, Parker Pearson, Michael, additional, Mainland, Ingrid, additional, Card, Nick, additional, Brown, Lisa, additional, Sharples, Niall, additional, Griffiths, David, additional, Allen, David, additional, Arbuckle, Benjamin, additional, Abell, Jordan T., additional, Duru, Güneş, additional, Mentzer, Susan M., additional, Munro, Natalie D., additional, Uzdurum, Melis, additional, Gülçur, Sevil, additional, Buitenhuis, Hijlke, additional, Gladyr, Elena, additional, Stiner, Mary C., additional, Pöllath, Nadja, additional, Özbaşaran, Mihriban, additional, Krebs, Stefan, additional, Burger, Joachim, additional, Frantz, Laurent, additional, Medugorac, Ivica, additional, Bradley, Daniel G., additional, and Peters, Joris, additional

Published
2024
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6. Ancient goat genomes reveal mosaic domestication in the Fertile Crescent

Author

Daly, Kevin G., Delser, Pierpaolo Maisano, Mullin, Victoria E., Scheu, Amelie, Mattiangeli, Valeria, Teasdale, Matthew D., Hare, Andrew J., Burger, Joachim, Verdugo, Marta Pereira, Collins, Matthew J., Kehati, Ron, Erek, Cevdet Merih, Bar-Oz, Guy, Pompanon, François, Cumer, Tristan, Çakırlar, Canan, Mohaseb, Azadeh Fatemeh, Decruyenaere, Delphine, Davoudi, Hossein, Çevik, Özlem, Rollefson, Gary, Vigne, Jean-Denis, Khazaeli, Roya, Fathi, Homa, Doost, Sanaz Beizaee, Sorkhani, Roghayeh Rahimi, Vahdati, Ali Akbar, Sauer, Eberhard W., Kharanaghi, Hossein Azizi, Maziar, Sepideh, Gasparian, Boris, Pinhasi, Ron, Martin, Louise, Orton, David, Arbuckle, Benjamin S., Benecke, Norbert, Manica, Andrea, Horwitz, Liora Kolska, Mashkour, Marjan, and Bradley, Daniel G.

Published
2018

8. Legacies of Taste: Mounting East Asian Paintings at the Smithsonian's National Museum of Asian Art.

Author

Brooks, Kit and Hare, Andrew

Subjects
NATIONAL museums, ART museums, PHOTOGRAPH albums, CHINESE painting, ASIAN art, PANEL painting, AMERICAN art
Abstract

The American industrialist Charles Lang Freer (1854–1919) amassed an outstanding collection of Asian, Near Eastern, and contemporary American art that he bequeathed to the Smithsonian Institution in 1906, together with plans for a museum to house his collection, the Freer Gallery of Art. Deeply influenced by the innovative American artist and Japoniste James McNeill Whistler (1834–1903), Freer envisioned the museum as a holistic setting for his collection, harmonizing aesthetics from both East and West. Freer's meticulous attention to design and detail extended to the mountings for his large collection of Chinese and Japanese paintings. His plans included hiring scroll mounters from Japan to remount over 350 of the paintings onto panels, choosing antique textiles to suit his taste, a taste inspired by antiquarian trends. Together with archival records and textile sample books, an album of photographs and other mementos from the Miura family of mounters recently acquired by the museum elucidates this remarkable achievement and the historical context of Japanese scroll mounting in the late nineteenth and early twentieth century. [ABSTRACT FROM AUTHOR]

Published
2024
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9. Looking Back, Looking Forward: The Past 15 Years of Mathematics Education in 'CJSTME'

Author

Hare, Andrew and Ng, Oi-Lam

Abstract

In this article, we review the publications served by the "Canadian Journal of Science, Mathematics and Technology Education" in the past 15 years, specific to the field of mathematics education, and make connections with development of the field. In particular, we adopt current Editor-in-Chief John Wallace's (2009) approach of "looking back, looking forward," to reflect on the journal's development both qualitatively, by recapping significant moments of the journal and highlighting recurrent themes, and quantitatively, by reviewing the number of contributions in terms of country, language, and genre. In looking forward, we inform a discussion of future directions of the journal.

Published
2015
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15. Exceptional ancient DNA preservation and fibre remains of a Sasanian saltmine sheep mummy in Chehrābād, Iran

Author

Rossi, Conor, primary, Ruß-Popa, Gabriela, additional, Mattiangeli, Valeria, additional, McDaid, Fionnuala, additional, Hare, Andrew J., additional, Davoudi, Hossein, additional, Laleh, Haeedeh, additional, Lorzadeh, Zahra, additional, Khazaeli, Roya, additional, Fathi, Homa, additional, Teasdale, Matthew D., additional, A'ali, Abolfazl, additional, Stöllner, Thomas, additional, Mashkour, Marjan, additional, and Daly, Kevin G., additional

Published
2021
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17. The influence of soybean population and POST herbicide application timing on in-season and subsequent-season Palmer amaranth (Amaranthus palmeri) control and economic returns

Author

Mahoney, Denis J., primary, Jordan, David L., additional, Hare, Andrew T., additional, Roma-Burgos, Nilda, additional, Jennings, Katherine M., additional, Leon, Ramon G., additional, Vann, Matthew C., additional, Everman, Wesley J., additional, and Cahoon, Charles W., additional

Published
2020
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19. Peanut and soybean response to cropping systems including corn, cotton, and grain sorghum

Author

Jordan, David, primary, Hare, Andrew, additional, Johnson, Dewayne, additional, Alston, Joel, additional, Alston, Trevor, additional, Ambrose, Derek, additional, Callis, David, additional, Corbett, Tommy, additional, Hoggard, Riley, additional, Stevens, Brian, additional, Wilkins, Reginald, additional, Shew, Barbara, additional, and Brandenburg, Rick, additional

Published
2020
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22. Ancient cattle genomics, origins, and rapid turnover in the Fertile Crescent

Author

Verdugo, Marta Pereira, Mullin, Victoria E., Scheu, Amelie, Mattiangeli, Valeria, Daly, Kevin G., Delser, Pierpaolo Maisano, Hare, Andrew J., Burger, Joachim, Collins, Matthew J., Kehati, Ron, Hesse, Paula, Fulton, Deirdre, Sauer, Eberhard W., Mohaseb, Fatemeh A., Davoudi, Hossein, Khazaeli, Roya, Lhuillier, Johanna, Rapin, Claude, Ebrahimi, Saeed, Khasanov, Mutalib, Vahidi, S. M. Farhad, MacHugh, David E., Ertugrul, Okan, Koukouli-Chrysanthaki, Chaido, Sampson, Adamantios, Kazantzis, George, Kontopoulos, Ioannis, Bulatović, Jelena, Dimitrijević, Ivana, Mikdad, Abdesalam, Benecke, Norbert, Linstaedter, Joerg, Sablin, Mikhail, Bendrey, Robin, Gourichon, Lionel, Arbuckle, Benjamin S., Mashkour, Marjan, Orton, David, Horwitz, Liora Kolska, Teasdale, Matthew D., Bradley, Daniel G., Verdugo, Marta Pereira, Mullin, Victoria E., Scheu, Amelie, Mattiangeli, Valeria, Daly, Kevin G., Delser, Pierpaolo Maisano, Hare, Andrew J., Burger, Joachim, Collins, Matthew J., Kehati, Ron, Hesse, Paula, Fulton, Deirdre, Sauer, Eberhard W., Mohaseb, Fatemeh A., Davoudi, Hossein, Khazaeli, Roya, Lhuillier, Johanna, Rapin, Claude, Ebrahimi, Saeed, Khasanov, Mutalib, Vahidi, S. M. Farhad, MacHugh, David E., Ertugrul, Okan, Koukouli-Chrysanthaki, Chaido, Sampson, Adamantios, Kazantzis, George, Kontopoulos, Ioannis, Bulatović, Jelena, Dimitrijević, Ivana, Mikdad, Abdesalam, Benecke, Norbert, Linstaedter, Joerg, Sablin, Mikhail, Bendrey, Robin, Gourichon, Lionel, Arbuckle, Benjamin S., Mashkour, Marjan, Orton, David, Horwitz, Liora Kolska, Teasdale, Matthew D., and Bradley, Daniel G.

Abstract

Genome-wide analysis of 67 ancient Near Eastern cattle, Bos taurus, remains reveals regional variation that has since been obscured by admixture in modern populations. Comparisons of genomes of early domestic cattle to their aurochs progenitors identify diverse origins with separate introgressions of wild stock. A later region-wide Bronze Age shift indicates rapid and widespread introgression of zebu, Bos indicus, from the Indus Valley. This process was likely stimulated at the onset of the current geological age, similar to 4.2 thousand years ago, by a widespread multicentury drought. In contrast to genome-wide admixture, mitochondrial DNA stasis supports that this introgression was male-driven, suggesting that selection of arid-adapted zebu bulls enhanced herd survival. This human-mediated migration of zebu-derived genetics has continued through millennia, altering tropical herding on each continent.

Published
2019

24. Ancient cattle genomics, origins, and rapid turnover in the Fertile Crescent

Author

Verdugo, Marta Pereira, primary, Mullin, Victoria E., additional, Scheu, Amelie, additional, Mattiangeli, Valeria, additional, Daly, Kevin G., additional, Maisano Delser, Pierpaolo, additional, Hare, Andrew J., additional, Burger, Joachim, additional, Collins, Matthew J., additional, Kehati, Ron, additional, Hesse, Paula, additional, Fulton, Deirdre, additional, Sauer, Eberhard W., additional, Mohaseb, Fatemeh A., additional, Davoudi, Hossein, additional, Khazaeli, Roya, additional, Lhuillier, Johanna, additional, Rapin, Claude, additional, Ebrahimi, Saeed, additional, Khasanov, Mutalib, additional, Vahidi, S. M. Farhad, additional, MacHugh, David E., additional, Ertuğrul, Okan, additional, Koukouli-Chrysanthaki, Chaido, additional, Sampson, Adamantios, additional, Kazantzis, George, additional, Kontopoulos, Ioannis, additional, Bulatovic, Jelena, additional, Stojanović, Ivana, additional, Mikdad, Abdesalam, additional, Benecke, Norbert, additional, Linstädter, Jörg, additional, Sablin, Mikhail, additional, Bendrey, Robin, additional, Gourichon, Lionel, additional, Arbuckle, Benjamin S., additional, Mashkour, Marjan, additional, Orton, David, additional, Horwitz, Liora Kolska, additional, Teasdale, Matthew D., additional, and Bradley, Daniel G., additional

Published
2019
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33. More Reliable Dating of Japanese Silk Mounting Textiles for Conservation Decisions: Effects of Silk Processing on Silk Surface Morphology and Aspartic Acid Racemization.

Author

Shimada, Chika Mori, McCarthy, Blythe, Rollman, Christopher M., Hare, Andrew, Ueda, Jiro, and Moini, Mehdi

Abstract

Dating silk mounting textiles is important for understanding their condition and susceptibility to degradation. Amino acid racemization is a technique currently used for this purpose. The research presented here aimed to clarify when this technique is reliable and when it is not. Silk fibers taken from a cocoon and from Japanese mounting textiles were studied using optical microscopy to document surface roughness. Chiral capillary electrophoresis mass spectrometry for amino acid racemization dating (AAR), liquid chromatography mass spectrometry for dye analysis, and FTIR for analysis of sericin and other materials adhering to the silk were also used. A change from rough fiber surfaces (greater than a hundred years old) to smooth fiber surfaces (less than a hundred years) was found. This correlated with the time of the introduction of Western degumming methods in Japan. Synthetic dyes were not found on the earlier silk fibers with rough surfaces. AAR dating measurements on rough surfaced fibers with remaining sericin correlated better with the estimated age of the silk fabrics than fibers with smooth surfaces, suggesting the technique should only be used for silk fibers with rough surfaces. A screening method for fibers for AAR analysis was outlined. [ABSTRACT FROM AUTHOR]

Published
2023
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34. Exceptional ancient DNA preservation and fibre remains of a Sasanian saltmine sheep mummy in Chehrābād, Iran

Author

Marjan Mashkour, Homa Fathi, Andrew J. Hare, Thomas Stöllner, Valeria Mattiangeli, Zahra Lorzadeh, Hossein Davoudi, Roya Khazaeli, Conor Rossi, Kevin G. Daly, Gabriela Ruß-Popa, Haeedeh Laleh, Abolfazl Aali, Fionnuala McDaid, Matthew D. Teasdale, Archéozoologie, archéobotanique : sociétés, pratiques et environnements (AASPE), Muséum national d'Histoire naturelle (MNHN)-Centre National de la Recherche Scientifique (CNRS), Rossi, Conor [0000-0003-4561-8878], Ruß-Popa, Gabriela [0000-0001-8492-6238], Mattiangeli, Valeria [0000-0001-9785-1714], Hare, Andrew J. [0000-0001-8595-6965], Davoudi, Hossein [0000-0002-5236-1444], Fathi, Homa [0000-0002-1764-0130], Teasdale, Matthew D. [0000-0002-7376-9975], A'ali, Abolfazl [0000-0002-6621-8665], Mashkour, Marjan [0000-0003-3630-9459], Daly, Kevin G. [0000-0002-5579-6144], Apollo - University of Cambridge Repository, and Teasdale, Matthew [0000-0002-7376-9975]

Subjects
0106 biological sciences, sheep, Taphonomy, [SHS.ARCHEO]Humanities and Social Sciences/Archaeology and Prehistory, Population genetics, Population, Zoology, Locus (genetics), Iran, 010603 evolutionary biology, 01 natural sciences, Genome, 03 medical and health sciences, 0302 clinical medicine, Research articles, Animals, Allele, DNA, Ancient, education, Genotyping, ancient DNA, 030304 developmental biology, 2. Zero hunger, 0303 health sciences, education.field_of_study, [SDV.GEN]Life Sciences [q-bio]/Genetics, biology, Mummies, biology.organism_classification, Agricultural and Biological Sciences (miscellaneous), mummy, Ancient DNA, Phenotype, Metagenomics, Evolutionary biology, [SDE]Environmental Sciences, General Agricultural and Biological Sciences, 030217 neurology & neurosurgery, Archaea
Abstract

International audience; Mummified remains have long attracted interest as a potential source of ancient DNA. However, mummification is a rare process that requires an anhydrous environment to rapidly dehydrate and preserve tissue before complete decomposition occurs. We present the whole-genome sequences (3.94 X) of an approximately 1600-year-old naturally mummified sheep recovered from Chehrābād, a salt mine in northwestern Iran. Comparative analyses of published ancient sequences revealed the remarkable DNA integrity of this mummy. Hallmarks of postmortem damage, fragmentation and hydrolytic deamination are substantially reduced, likely owing to the high salinity of this taphonomic environment. Metagenomic analyses reflect the profound influence of high-salt content on decomposition; its microbial profile is predominated by halophilic archaea and bacteria, possibly contributing to the remarkable preservation of the sample. Applying population genomic analyses, we find clustering of this sheep with Southwest Asian modern breeds, suggesting ancestry continuity. Genotyping of a locus influencing the woolly phenotype showed the presence of an ancestral ‘hairy’ allele, consistent with hair fibre imaging. This, along with derived alleles associated with the fat-tail phenotype, provides genetic evidence that Sasanian-period Iranians maintained specialized sheep flocks for different uses, with the ‘hairy’, ‘fat-tailed’-genotyped sheep likely kept by the rural community of Chehrābād's miners.

Published
2021

35. Ancient cattle genomics, origins, and rapid turnover in the Fertile Crescent

Author

Andrew J. Hare, David Orton, Jörg Linstädter, Okan Ertugrul, Abdesalam Mikdad, Pierpaolo Maisano Delser, Johanna Lhuillier, Eberhard Sauer, Adamantios Sampson, Jelena Bulatović, Marjan Mashkour, Victoria E. Mullin, Marta Pereira Verdugo, Benjamin S. Arbuckle, Hossein Davoudi, Ron Kehati, Norbert Benecke, Mikhail V. Sablin, David E. MacHugh, Joachim Burger, Robin Bendrey, S. M. Farhad Vahidi, Kevin G. Daly, Matthew J. Collins, Matthew D. Teasdale, Saeed Ebrahimi, Liora Kolska Horwitz, Daniel G. Bradley, Roya Khazaeli, Fatemeh Azadeh Mohaseb, Chaido Koukouli-Chrysanthaki, George Kazantzis, Claude Rapin, Paula Wapnish Hesse, Amelie Scheu, Ivana Stojanović, Valeria Mattiangeli, Lionel Gourichon, Mutalib Khasanov, Deirdre Fulton, Ioannis Kontopoulos, Tarbiat Modares University [Tehran], ARCHEORIENT - Environnements et sociétés de l'Orient ancien (Archéorient), Université Lumière - Lyon 2 (UL2)-Centre National de la Recherche Scientifique (CNRS), University of Tehran, Zoological Institute, Russian Academy of Sciences [Moscow] (RAS), University of Reading (UOR), Centre d'Études Préhistoire, Antiquité, Moyen-Age (CEPAM), Université Nice Sophia Antipolis (... - 2019) (UNS), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Centre National de la Recherche Scientifique (CNRS), Department of Anthropology, Baylor University, Baylor University, Archéozoologie, archéobotanique : sociétés, pratiques et environnements (AASPE), Muséum national d'Histoire naturelle (MNHN)-Centre National de la Recherche Scientifique (CNRS), HEC Paris - Recherche - Hors Laboratoire, Ecole des Hautes Etudes Commerciales (HEC Paris), Verdugo, Marta Pereira [0000-0003-1573-2493], Mullin, Victoria E [0000-0002-2604-2976], Scheu, Amelie [0000-0001-9455-0772], Daly, Kevin G [0000-0002-5579-6144], Maisano Delser, Pierpaolo [0000-0002-1844-1715], Hare, Andrew J [0000-0001-8595-6965], Burger, Joachim [0000-0001-9972-1868], Collins, Matthew J [0000-0003-4226-5501], Fulton, Deirdre [0000-0002-5922-5461], Mohaseb, Fatemeh A [0000-0003-3130-6603], Davoudi, Hossein [0000-0002-5236-1444], Ebrahimi, Saeed [0000-0003-4994-5892], MacHugh, David E [0000-0002-8112-4704], Ertuğrul, Okan [0000-0002-2949-1558], Kontopoulos, Ioannis [0000-0001-5591-8917], Sablin, Mikhail [0000-0002-2773-7454], Bendrey, Robin [0000-0001-5286-1601], Gourichon, Lionel [0000-0002-5160-5902], Arbuckle, Benjamin S [0000-0002-5445-5516], Mashkour, Marjan [0000-0003-3630-9459], Orton, David [0000-0003-4069-8004], Teasdale, Matthew D [0000-0002-7376-9975], Bradley, Daniel G [0000-0001-7335-7092], and Apollo - University of Cambridge Repository

Subjects
0301 basic medicine, 010506 paleontology, Mitochondrial DNA, [SHS.ARCHEO]Humanities and Social Sciences/Archaeology and Prehistory, Human Migration, Introgression, Zoology, Genomics, 01 natural sciences, DNA, Mitochondrial, [SHS]Humanities and Social Sciences, Domestication, Evolution, Molecular, 03 medical and health sciences, Bronze Age, Animals, [SDV.BBM.BC]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Biochemistry [q-bio.BM], 0105 earth and related environmental sciences, [SDV.EE]Life Sciences [q-bio]/Ecology, environment, [SDV.GEN]Life Sciences [q-bio]/Genetics, Multidisciplinary, Genome, biology, Human migration, business.industry, Aurochs, Zebu, biology.organism_classification, humanities, 030104 developmental biology, Fertility, Cattle, business
Abstract

Cattle were domesticated ∼10,000 years ago, but analysis of modern breeds has not elucidated their origins. Verdugo et al. performed genome-wide analysis of 67 ancient Near Eastern Bos taurus DNA samples. Several populations of ancient aurochs were progenitors of domestic cows. These genetic lineages mixed ∼4000 years ago in a region around the Indus Valley. Interestingly, mitochondrial analysis indicated that genetic material likely derived from arid-adapted Bos indicus (zebu) bulls was introduced by introgression.Science, this issue p. 173Genome-wide analysis of 67 ancient Near Eastern cattle, Bos taurus, remains reveals regional variation that has since been obscured by admixture in modern populations. Comparisons of genomes of early domestic cattle to their aurochs progenitors identify diverse origins with separate introgressions of wild stock. A later region-wide Bronze Age shift indicates rapid and widespread introgression of zebu, Bos indicus, from the Indus Valley. This process was likely stimulated at the onset of the current geological age, ~4.2 thousand years ago, by a widespread multicentury drought. In contrast to genome-wide admixture, mitochondrial DNA stasis supports that this introgression was male-driven, suggesting that selection of arid-adapted zebu bulls enhanced herd survival. This human-mediated migration of zebu-derived genetics has continued through millennia, altering tropical herding on each continent.

Published
2019

36. Ancient goat genomes reveal mosaic domestication in the Fertile Crescent

Author

Matthew J. Collins, Hossein Davoudi, Liora Kolska Horwitz, Boris Gasparian, Hossein Azizi Kharanaghi, Victoria E. Mullin, Daniel G. Bradley, Guy Bar-Oz, Marjan Mashkour, Marta Pereira Verdugo, Sepideh Maziar, Roghayeh Rahimi Sorkhani, Ali A. Vahdati, Delphine Decruyenaere, Azadeh Fatemeh Mohaseb, Andrew J. Hare, Özlem Çevik, David Orton, Jean-Denis Vigne, Norbert Benecke, Cevdet Merih Erek, Gary O. Rollefson, Matthew D. Teasdale, Eberhard Sauer, Valeria Mattiangeli, Canan Çakirlar, Andrea Manica, Joachim Burger, Ron Pinhasi, Homa Fathi, Tristan Cumer, Sanaz Beizaee Doost, Ron Kehati, Kevin G. Daly, Benjamin S. Arbuckle, Louise Martin, Pierpaolo Maisano Delser, François Pompanon, Roya Khazaeli, Amelie Scheu, Transplant Research Program [Boston, MA, USA], Boston Children's Hospital, Trinity College Dublin, Centre for Ultrahigh Bandwidth Devices for Optical Systems (CUDOS), The University of Sydney, Zinman Institute of Archaeology [Haifa], University of Haifa [Haifa], Laboratoire d'Ecologie Alpine (LECA ), Université Savoie Mont Blanc (USMB [Université de Savoie] [Université de Chambéry])-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes [2016-2019] (UGA [2016-2019]), University of Groningen [Groningen], Archéozoologie, archéobotanique : sociétés, pratiques et environnements (AASPE), Muséum national d'Histoire naturelle (MNHN)-Centre National de la Recherche Scientifique (CNRS), Tarbiat Modares University [Tehran], Whitman College, Goethe-Universität Frankfurt am Main, National Academy of Sciences of the Republic of Armenia [Yerevan] (NAS RA), School of Archaeology, University College Dublin [Dublin] (UCD), University College of London [London] (UCL), HEC Paris - Recherche - Hors Laboratoire, Ecole des Hautes Etudes Commerciales (HEC Paris), Department of Anthropology, Baylor University, Baylor University, Daly, Kevin G [0000-0002-5579-6144], Maisano Delser, Pierpaolo [0000-0002-1844-1715], Mullin, Victoria E [0000-0002-2604-2976], Teasdale, Matthew D [0000-0002-7376-9975], Hare, Andrew J [0000-0001-8595-6965], Burger, Joachim [0000-0001-9972-1868], Verdugo, Marta Pereira [0000-0003-1573-2493], Collins, Matthew J [0000-0003-4226-5501], Pompanon, François [0000-0003-4600-0172], Mohaseb, Azadeh Fatemeh [0000-0003-3130-6603], Decruyenaere, Delphine [0000-0001-5496-7370], Davoudi, Hossein [0000-0002-5236-1444], Çevik, Özlem [0000-0001-5442-3744], Rollefson, Gary [0000-0002-1083-6675], Maziar, Sepideh [0000-0002-2253-7680], Pinhasi, Ron [0000-0003-3944-615X], Martin, Louise [0000-0002-2083-813X], Orton, David [0000-0003-4069-8004], Arbuckle, Benjamin S [0000-0002-5445-5516], Manica, Andrea [0000-0003-1895-450X], Mashkour, Marjan [0000-0003-3630-9459], Bradley, Daniel G [0000-0001-7335-7092], Apollo - University of Cambridge Repository, and Archaeology of Northwestern Europe

Subjects
0301 basic medicine, Follistatin, MESH: Domestication, AGRICULTURE, CATTLE, MESH: Follistatin, MESH: Africa, Genome, [SHS]Humanities and Social Sciences, Domestication, 0601 history and archaeology, MESH: Animals, MESH: Genetic Variation, MESH: Phylogeny, Phylogeny, ZAGROS, media_common, 2. Zero hunger, [SDV.EE]Life Sciences [q-bio]/Ecology, environment, Multidisciplinary, Middle East, 060102 archaeology, Mosaicism, MESH: Asia, Goats, 06 humanities and the arts, Europe, Animals, Domestic, MESH: Mosaicism, Reproduction, TRAITS, Asia, [SHS.ARCHEO]Humanities and Social Sciences/Archaeology and Prehistory, media_common.quotation_subject, Biology, DNA, Mitochondrial, MESH: Goats, Mosaic, 03 medical and health sciences, Phylogenetics, Genetic variation, Animals, MESH: Genome, MESH: Animals, Domestic, DNA, Ancient, Dietary change, [SDV.BBM.BC]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Biochemistry [q-bio.BM], [SDV.GEN]Life Sciences [q-bio]/Genetics, NEAR-EAST, MESH: DNA, Mitochondrial, Genetic Variation, MESH: DNA, Ancient, GENE, MODEL, 030104 developmental biology, SHEEP, Evolutionary biology, ORIGINS, Africa, MESH: Europe
Abstract

How humans got their goatsLittle is known regarding the location and mode of the early domestication of animals such as goats for husbandry. To investigate the history of the goat, Dalyet al.sequenced mitochondrial and nuclear sequences from ancient specimens ranging from hundreds to thousands of years in age. Multiple wild populations contributed to the origin of modern goats during the Neolithic. Over time, one mitochondrial type spread and became dominant worldwide. However, at the whole-genome level, modern goat populations are a mix of goats from different sources and provide evidence for a multilocus process of domestication in the Near East. Furthermore, the patterns described support the idea of multiple dispersal routes out of the Fertile Crescent region by domesticated animals and their human counterparts.Science, this issue p.85

Published
2018
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37. Leveraging the Outpatient Pharmacy to Reduce Medication Waste in Pediatric Asthma Hospitalizations.

Author

Hoefgen ER, Jones Y, Courter J, Hare A, Garcia JAT, and Simmons J

Subjects
Administration, Inhalation, Child, Hospitals, Pediatric, Humans, Adrenal Cortex Hormones therapeutic use, Asthma drug therapy, Hospitalization, Inpatients, Insurance Coverage economics, Pharmacy
Abstract

Background and Objective: Previous local quality improvement focused on discharging patients with inhaled corticosteroids (ICS) "in-hand" decreased healthcare reutilization after hospitalization for an asthma exacerbation. However, as a result of these new processes, some patients admitted for an asthma exacerbation received more than one ICS inhaler during their admission, contributing to medication waste and potential patient confusion regarding their discharge medication regimen. We sought to decrease this waste., Methods: We conducted a quality improvement project to reduce the prescribing of multiple ICS inhalers to patients at a large academic children's hospital. Our primary outcome measure was the monthly percentage of patients admitted with an asthma exacerbation who were administered more than one ICS inhaler. A secondary outcome measure evaluated the reliability of the new process of using the hospital-based outpatient pharmacy to supply ICS "in-hand" and verify insurance coverage. After the process map review, we hypothesized a delay in the initial ICS treatment decision would allow for both a finalized discharge medication plan and a standardized process to verify outpatient insurance coverage., Results: The mean percentage of patients receiving more than one ICS inhaler decreased from our baseline of 7.4% to 0.7%. Verification of outpatient prescription insurance coverage via the outpatient pharmacy increased from 0.7% to 50%. The average inpatient cost (average wholesale price) for ICS decreased by 62% to $90.25., Conclusions: Our process change to use the outpatient pharmacy to dispense and verify insurance coverage for ICS medication was associated with a reduction in medication waste during admission for an asthma exacerbation.

Published
2020
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