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1. Correction: Epidemiological Changes and Improvement in Outcomes of Infective Endocarditis in Europe in the Twenty-First Century: An International Collaboration on Endocarditis (ICE) Prospective Cohort Study (2000–2012)

Author

Ambrosioni, Juan, Hernández-Meneses, Marta, Durante-Mangoni, Emanuele, Tattevin, Pierre, Olaison, Lars, Freiberger, Tomas, Hurley, John, Hannan, Margaret M., Chu, Vivian, Hoen, Bruno, Moreno, Asunción, Cuervo, Guillermo, Llopis, Jaume, and Miró, José M.

Published
2023
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2. Epidemiological Changes and Improvement in Outcomes of Infective Endocarditis in Europe in the Twenty-First Century: An International Collaboration on Endocarditis (ICE) Prospective Cohort Study (2000–2012)

Author

Ambrosioni, Juan, Hernández-Meneses, Marta, Durante-Mangoni, Emanuele, Tattevin, Pierre, Olaison, Lars, Freiberger, Tomas, Hurley, John, Hannan, Margaret M., Chu, Vivian, Hoen, Bruno, Moreno, Asunción, Cuervo, Guillermo, Llopis, Jaume, and Miró, José M.

Published
2023
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3. Clinical characteristics and outcome of infective endocarditis due to Abiotrophia and Granulicatella compared to Viridans group streptococci

Author

Téllez, Adrián, Ambrosioni, Juan, Hernández-Meneses, Marta, Llopis, Jaume, Ripa, Marco, Chambers, Stephen T., Holland, David, Almela, Manel, Fernández-Hidalgo, Núria, Almirante, Benito, Bouza, Emilio, Strahilevitz, Jacob, Hannan, Margaret M, Harkness, John, Kanafani, Zeina A., Lalani, Tahaniyat, Lang, Selwyn, Raymond, Nigel, Read, Kerry, Vinogradova, Tatiana, Woods, Christopher W., Wray, Dannah, Moreno, Asuncion, Chu, Vivian H., and Miro, Jose M

Published
2022
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8. Association between the timing of surgery for complicated, left-sided infective endocarditis and survival

Author

Wang, Andrew, Chu, Vivian H., Athan, Eugene, Delahaye, Francois, Freiberger, Tomas, Lamas, Cristiane, Miro, Jose M., Strahilevitz, Jacob, Tribouilloy, Christophe, Durante-Mangoni, Emanuele, Pericas, Juan M., Fernández-Hidalgo, Nuria, Nacinovich, Francisco, Barsic, Bruno, Giannitsioti, Efthymia, Hurley, John P., Hannan, Margaret M., and Park, Lawrence P.

Published
2019
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12. Infectious Complications

Author

Deniz, Ezin, Feldmann, Christina, Schmitto, Jan D., Hannan, Margaret M., Montalto, Andrea, editor, Loforte, Antonio, editor, Musumeci, Francesco, editor, Krabatsch, Thomas, editor, Slaughter, Mark S., editor, and Amarelli, Cristiano, With contrib. by

Published
2017
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18. The 2023 Duke-International Society for Cardiovascular Infectious Diseases Criteria for Infective Endocarditis:Updating the Modified Duke Criteria [Inkl. Correction]

Author

Fowler, Vance G., Durack, David T., Selton-Suty, Christine, Athan, Eugene, Bayer, Arnold S., Chamis, Anna Lisa, Dahl, Anders, Dibernardo, Louis, Durante-Mangoni, Emanuele, Duval, Xavier, Fortes, Claudio Querido, Fosbol, Emil, Hannan, Margaret M., Hasse, Barbara, Hoen, Bruno, Karchmer, Adolf W., Mestres, Carlos A., Petti, Cathy A., Pizzi, Maria Nazarena, Preston, Stephen D., Roque, Albert, Vandenesch, Francois, Van Der Meer, Jan T.M., Van Der Vaart, Thomas W., Miro, Jose M., Fowler, Vance G., Durack, David T., Selton-Suty, Christine, Athan, Eugene, Bayer, Arnold S., Chamis, Anna Lisa, Dahl, Anders, Dibernardo, Louis, Durante-Mangoni, Emanuele, Duval, Xavier, Fortes, Claudio Querido, Fosbol, Emil, Hannan, Margaret M., Hasse, Barbara, Hoen, Bruno, Karchmer, Adolf W., Mestres, Carlos A., Petti, Cathy A., Pizzi, Maria Nazarena, Preston, Stephen D., Roque, Albert, Vandenesch, Francois, Van Der Meer, Jan T.M., Van Der Vaart, Thomas W., and Miro, Jose M.

Abstract

The microbiology, epidemiology, diagnostics, and treatment of infective endocarditis (IE) have changed significantly since the Duke Criteria were published in 1994 and modified in 2000. The International Society for Cardiovascular Infectious Diseases (ISCVID) convened a multidisciplinary Working Group to update the diagnostic criteria for IE. The resulting 2023 Duke-ISCVID IE Criteria propose significant changes, including new microbiology diagnostics (enzyme immunoassay for Bartonella species, polymerase chain reaction, amplicon/metagenomic sequencing, in situ hybridization), imaging (positron emission computed tomography with 18F-fluorodeoxyglucose, cardiac computed tomography), and inclusion of intraoperative inspection as a new Major Clinical Criterion. The list of “typical” microorganisms causing IE was expanded and includes pathogens to be considered as typical only in the presence of intracardiac prostheses. The requirements for timing and separate venipunctures for blood cultures were removed. Last, additional predisposing conditions (transcatheter valve implants, endovascular cardiac implantable electronic devices, prior IE) were clarified. These diagnostic criteria should be updated periodically by making the Duke-ISCVID Criteria available online as a “Living Document.”, The microbiology, epidemiology, diagnostics, and treatment of infective endocarditis (IE) have changed significantly since the Duke Criteria were published in 1994 and modified in 2000. The International Society for Cardiovascular Infectious Diseases (ISCVID) convened a multidisciplinary Working Group to update the diagnostic criteria for IE. The resulting 2023 Duke-ISCVID IE Criteria propose significant changes, including new microbiology diagnostics (enzyme immunoassay for Bartonella species, polymerase chain reaction, amplicon/metagenomic sequencing, in situ hybridization), imaging (positron emission computed tomography with 18F-fluorodeoxyglucose, cardiac computed tomography), and inclusion of intraoperative inspection as a new Major Clinical Criterion. The list of "typical"microorganisms causing IE was expanded and includes pathogens to be considered as typical only in the presence of intracardiac prostheses. The requirements for timing and separate venipunctures for blood cultures were removed. Last, additional predisposing conditions (transcatheter valve implants, endovascular cardiac implantable electronic devices, prior IE) were clarified. These diagnostic criteria should be updated periodically by making the Duke-ISCVID Criteria available online as a "Living Document."

Published
2023

19. The 2023 Duke-International Society for Cardiovascular Infectious Diseases Criteria for Infective Endocarditis: Updating the Modified Duke Criteria

Author

Fowler, Vance G, primary, Durack, David T, additional, Selton-Suty, Christine, additional, Athan, Eugene, additional, Bayer, Arnold S, additional, Chamis, Anna Lisa, additional, Dahl, Anders, additional, DiBernardo, Louis, additional, Durante-Mangoni, Emanuele, additional, Duval, Xavier, additional, Fortes, Claudio Querido, additional, Fosbøl, Emil, additional, Hannan, Margaret M, additional, Hasse, Barbara, additional, Hoen, Bruno, additional, Karchmer, Adolf W, additional, Mestres, Carlos A, additional, Petti, Cathy A, additional, Pizzi, María Nazarena, additional, Preston, Stephen D, additional, Roque, Albert, additional, Vandenesch, Francois, additional, van der Meer, Jan T M, additional, van der Vaart, Thomas W, additional, and Miro, Jose M, additional

Published
2023
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20. Impact of Early Valve Surgery on Outcome of Staphylococcus aureus Prosthetic Valve Infective Endocarditis: Analysis in the International Collaboration of Endocarditis–Prospective Cohort Study

Author

ICE Prospective Investigators, Chirouze, Catherine, Alla, François, Fowler, Vance G., Sexton, Daniel J., Corey, G. Ralph, Chu, Vivian H., Wang, Andrew, Erpelding, Marie-Line, Durante-Mangoni, Emanuele, Fernández-Hidalgo, Nuria, Giannitsioti, Efthymia, Hannan, Margaret M., Lejko-Zupanc, Tatjana, Miró, José M., Muñoz, Patricia, Murdoch, David R., Tattevin, Pierre, Tribouilloy, Christophe, and Hoen, Bruno

Published
2015

23. Infective Endocarditis in Patients on Chronic Hemodialysis

Author

Pericàs, Juan M., primary, Llopis, Jaume, additional, Jiménez-Exposito, Maria Jesús, additional, Kourany, Wissam M., additional, Almirante, Benito, additional, Carosi, Giampiero, additional, Durante-Mangoni, Emanuele, additional, Fortes, Claudio Querido, additional, Giannitsioti, Efthymia, additional, Lerakis, Stamatios, additional, Montagna-Mella, Rodrigo, additional, Ambrosioni, Juan, additional, Tan, Ru-San, additional, Mestres, Carlos A., additional, Wray, Dannah, additional, Pachirat, Orathai, additional, Moreno, Asuncion, additional, Chu, Vivian H., additional, de Lazzari, Elisa, additional, Fowler, Vance G., additional, Miró, Jose M., additional, Clara, Liliana, additional, Sanchez, Marisa, additional, Casabé, José, additional, Cortes, Claudia, additional, Nacinovich, Francisco, additional, Oses, Pablo Fernandez, additional, Ronderos, Ricardo, additional, Sucari, Adriana, additional, Thierer, Jorge, additional, Altclas, Javier, additional, Kogan, Silvia, additional, Spelman, Denis, additional, Athan, Eugene, additional, Harris, Owen, additional, Kennedy, Karina, additional, Tan, Ren, additional, Gordon, David, additional, Papanicolas, Lito, additional, Korman, Tony, additional, Kotsanas, Despina, additional, Dever, Robyn, additional, Jones, Phillip, additional, Konecny, Pam, additional, Lawrence, Richard, additional, Rees, David, additional, Ryan, Suzanne, additional, Feneley, Michael P., additional, Harkness, John, additional, Post, Jeffrey, additional, Reinbott, Porl, additional, Gattringer, Rainer, additional, Wiesbauer, Franz, additional, Andrade, Adriana Ribas, additional, Passos de Brito, Ana Cláudia, additional, Guimarães, Armenio Costa, additional, Grinberg, Max, additional, Mansur, Alfredo José, additional, Siciliano, Rinaldo Focaccia, additional, Varejao Strabelli, Tania Mara, additional, Campos Vieira, Marcelo Luiz, additional, de Medeiros Tranchesi, Regina Aparecida, additional, Paiva, Marcelo Goulart, additional, de Oliveira Ramos, Auristela, additional, Weksler, Clara, additional, Ferraiuoli, Giovanna, additional, Golebiovski, Wilma, additional, Lamas, Cristiane, additional, Karlowsky, James A., additional, Keynan, Yoav, additional, Morris, Andrew M., additional, Rubinstein, Ethan, additional, Jones, Sandra Braun, additional, Garcia, Patricia, additional, Cereceda, M., additional, Fica, Alberto, additional, Mella, Rodrigo Montagna, additional, Fernandez, Ricardo, additional, Franco, Liliana, additional, Gonzalez, Javier, additional, Jaramillo, Astrid Natalia, additional, Barsic, Bruno, additional, Bukovski, Suzana, additional, Krajinovic, Vladimir, additional, Pangercic, Ana, additional, Rudez, Igor, additional, Vincelj, Josip, additional, Freiberger, Tomas, additional, Pol, Jiri, additional, Zaloudikova, Barbora, additional, Ashour, Zainab, additional, El Kholy, Amani, additional, Mishaal, Marwa, additional, Osama, Dina, additional, Rizk, Hussien, additional, Aissa, Neijla, additional, Alauzet, Corentine, additional, Alla, Francois, additional, Campagnac, CHU Catherine, additional, Doco-Lecompte, Thanh, additional, Selton-Suty, Christine, additional, Casalta, Jean-Paul, additional, Fournier, Pierre-Edouard, additional, Habib, Gilbert, additional, Raoult, Didier, additional, Thuny, Franck, additional, Delahaye, Francois, additional, Delahaye, Armelle, additional, Vandenesch, Francois, additional, Donal, Erwan, additional, Donnio, Pierre Yves, additional, Flecher, Erwan, additional, Michelet, Christian, additional, Revest, Matthieu, additional, Tattevin, Pierre, additional, Chevalier, Florent, additional, Jeu, Antoine, additional, Rémadi, Jean Paul, additional, Rusinaru, Dan, additional, Tribouilloy, Christophe, additional, Bernard, Yvette, additional, Chirouze, Catherine, additional, Hoen, Bruno, additional, Leroy, Joel, additional, Plesiat, Patrick, additional, Naber, Christoph, additional, Neuerburg, Carl, additional, Mazaheri, Bahram, additional, Sophia Athanasia, Carl Neuerburg, additional, Deliolanis, Ioannis, additional, Giamarellou, Helen, additional, Thomas, Tsaganos, additional, Mylona, Elena, additional, Paniara, Olga, additional, Papanicolaou, Konstantinos, additional, Pyros, John, additional, Skoutelis, Athanasios, additional, Papanikolaou, Konstantinos, additional, Sharma, Gautam, additional, Francis, Johnson, additional, Nair, Lathi, additional, Thomas, Vinod, additional, Venugopal, Krishnan, additional, Hannan, Margaret M., additional, Hurley, John P., additional, Wanounou, Maor, additional, Gilon, Dan, additional, Israel, Sarah, additional, Korem, Maya, additional, Strahilevitz, Jacob, additional, Iossa, Domenico, additional, Orlando, Serena, additional, Ursi, Maria Paola, additional, Pafundi, Pia Clara, additional, D’Amico, Fabiana, additional, Bernardo, Mariano, additional, Cuccurullo, Susanna, additional, Dialetto, Giovanni, additional, Covino, Franco Enrico, additional, Manduca, Sabrina, additional, Della Corte, Alessandro, additional, De Feo, Marisa, additional, Tripodi, Marie Françoise, additional, Cecchi, Enrico, additional, De Rosa, Francesco, additional, Forno, Davide, additional, Imazio, Massimo, additional, Trinchero, Rita, additional, Grossi, Paolo, additional, Lattanzio, Mariangela, additional, Toniolo, Antonio, additional, Goglio, Antonio, additional, Raglio, Annibale, additional, Ravasio, Veronica, additional, Rizzi, Marco, additional, Suter, Fredy, additional, Magri, Silvia, additional, Signorini, Liana, additional, Kanafani, Zeina, additional, Kanj, Souha S., additional, Sharif-Yakan, Ahmad, additional, Abidin, Imran, additional, Tamin, Syahidah Syed, additional, Martínez, Eduardo Rivera, additional, Soto Nieto, Gabriel Israel, additional, van der Meer, Jan T.M., additional, Chambers, Stephen, additional, Holland, David, additional, Morris, Arthur, additional, Raymond, Nigel, additional, Read, Kerry, additional, Murdoch, David R., additional, Dragulescu, Stefan, additional, Ionac, Adina, additional, Mornos, Cristian, additional, Butkevich, O.M., additional, Chipigina, Natalia, additional, Kirill, Ozerecky, additional, Vadim, Kulichenko, additional, Vinogradova, Tatiana, additional, Edathodu, Jameela, additional, Halim, Magid, additional, Liew, Yee-Yun, additional, Lejko-Zupanc, Tatjana, additional, Logar, Mateja, additional, Mueller-Premru, Manica, additional, Commerford, Patrick, additional, Commerford, Anita, additional, Deetlefs, Eduan, additional, Hansa, Cass, additional, Ntsekhe, Mpiko, additional, Almela, Manel, additional, Azqueta, Manuel, additional, Brunet, Merce, additional, Castro, Pedro, additional, De Lazzari, Elisa, additional, Falces, Carlos, additional, Fuster, David, additional, Fita, Guillermina, additional, Garcia- de- la- Maria, Cristina, additional, Garcia-Gonzalez, Javier, additional, Gatell, Jose M., additional, Marco, Francesc, additional, Miró, José M., additional, Ortiz, José, additional, Ninot, Salvador, additional, Paré, J. Carlos, additional, Pericas, Juan M., additional, Quintana, Eduard, additional, Ramirez, Jose, additional, Rovira, Irene, additional, Sandoval, Elena, additional, Sitges, Marta, additional, Tellez, Adrian, additional, Tolosana, José M., additional, Vidal, Barbara, additional, Vila, Jordi, additional, Anguera, Ignasi, additional, Font, Bernat, additional, Guma, Joan Raimon, additional, Bermejo, Javier, additional, Bouza, Emilio, additional, Garcia Fernández, Miguel Angel, additional, Gonzalez-Ramallo, Victor, additional, Marín, Mercedes, additional, Muñoz, Patricia, additional, Pedromingo, Miguel, additional, Roda, Jorge, additional, Rodríguez-Créixems, Marta, additional, Solis, Jorge, additional, Fernandez-Hidalgo, Nuria, additional, Tornos, Pilar, additional, de Alarcón, Arístides, additional, Parra, Ricardo, additional, Alestig, Eric, additional, Johansson, Magnus, additional, Olaison, Lars, additional, Snygg-Martin, Ulrika, additional, Pachirat, Pimchitra, additional, Pussadhamma, Burabha, additional, Senthong, Vichai, additional, Casey, Anna, additional, Elliott, Tom, additional, Lambert, Peter, additional, Watkin, Richard, additional, Eyton, Christina, additional, Klein, John L., additional, Bradley, Suzanne, additional, Kauffman, Carol, additional, Bedimo, Roger, additional, Corey, G. Ralph, additional, Crowley, Anna Lisa, additional, Douglas, Pamela, additional, Drew, Laura, additional, Holland, Thomas, additional, Lalani, Tahaniyat, additional, Mudrick, Daniel, additional, Samad, Zaniab, additional, Sexton, Daniel, additional, Stryjewski, Martin, additional, Wang, Andrew, additional, Woods, Christopher W., additional, Cantey, Robert, additional, Steed, Lisa, additional, Dickerman, Stuart A., additional, Bonilla, Hector, additional, DiPersio, Joseph, additional, Salstrom, Sara-Jane, additional, Baddley, John, additional, Patel, Mukesh, additional, Peterson, Gail, additional, Stancoven, Amy, additional, Levine, Donald, additional, Riddle, Jonathan, additional, Rybak, Michael, additional, and Cabell, Christopher H., additional

Published
2021
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25. Prospective Cohort Study of Infective Endocarditis in People Who Inject Drugs

Author

Pericàs, Juan M., primary, Llopis, Jaume, additional, Athan, Eugene, additional, Hernández-Meneses, Marta, additional, Hannan, Margaret M., additional, Murdoch, David R., additional, Kanafani, Zeina, additional, Freiberger, Tomas, additional, Strahilevitz, Jacob, additional, Fernández-Hidalgo, Nuria, additional, Lamas, Cristiane, additional, Durante-Mangoni, Emanuele, additional, Tattevin, Pierre, additional, Nacinovich, Francisco, additional, Chu, Vivian H., additional, and Miró, José M., additional

Published
2021
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26. Beta-Hemolytic Streptococcal Infective Endocarditis: Characteristics and Outcomes From a Large, Multinational Cohort

Author

Fernández Hidalgo, Núria, primary, Gharamti, Amal A, primary, Aznar, María Luisa, primary, Almirante, Benito, primary, Yasmin, Mohamad, primary, Fortes, Claudio Querido, primary, Plesiat, Patrick, primary, Doco-Lecompte, Thanh, primary, Rizk, Hussein, primary, Wray, Dannah, primary, Lamas, Cristiane, primary, Durante-Mangoni, Emanuele, primary, Tattevin, Pierre, primary, Snygg-Martin, Ulrika, primary, Hannan, Margaret M, primary, Chu, Vivian H, primary, and Kanafani, Zeina A, primary

Published
2020
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27. International Society of Cardiovascular Infectious Diseases Guidelines for the Diagnosis, Treatment and Prevention of Disseminated Mycobacterium chimaera Infection Following Cardiac Surgery with Cardiopulmonary Bypass

Author

Hasse, Barbara, Hannan, Margaret M, Keller, Peter M, Maurer, Florian P, Sommerstein, Rami, Mertz, Dominik, et al, Bettex, Dominique, Schreiber, Peter W, Zweifel, Sandrine A, Sander, P, Schulthess, B, University of Zurich, and Hasse, Barbara

Subjects
10018 Ophthalmology Clinic, 10234 Clinic for Infectious Diseases, 10179 Institute of Medical Microbiology, 10216 Institute of Anesthesiology, 570 Life sciences, biology, 610 Medicine & health, 2725 Infectious Diseases, 2726 Microbiology (medical), 10020 Clinic for Cardiac Surgery
Published
2020

28. International Society of Cardiovascular Infectious Diseases Guidelines for the Diagnosis, Treatment and Prevention of Disseminated Mycobacterium chimaera Infection Following Cardiac Surgery with Cardiopulmonary Bypass: Guidelines

Author

Hasse, Barbara K., Hannan, Margaret M., Keller, Peter M., Maurer, Florian P., Sommerstein, Rami, Mertz, Dominik, Wagner, Dirk, Fernández-Hidalgo, Núria, Nomura, J., Manfrin, Vinicio, Béttex, Dominique A., and Hernandez-Conte, Antonio T.

Subjects
Cardiopulmonary bypass, education, Outbreaks, Mycobacterium chimaera, Mycobacterial, Guidelines, ISCVID, Infection, Disseminated, Heater-cooler device, health care economics and organizations, humanities
Abstract

Journal of Hospital Infection, 104 (2)

Published
2020
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31. Corrigendum to “association between the timing of surgery for complicated, left-sided infective endocarditis and survival”, American Heart Journal 2019, volume 210, April 2019, pages 108–116

Author

Wang, Andrew, primary, Chu, Vivian H., additional, Athan, Eugene, additional, Delahaye, Francois, additional, Freiberger, Tomas, additional, Lamas, Cristiane, additional, Miro, Jose M., additional, Strahilevitz, Jacob, additional, Tribouilloy, Christophe, additional, Durante-Mangoni, Emanuele, additional, Pericas, Juan M., additional, Fernández-Hidalgo, Nuria, additional, Nacinovich, Francisco, additional, Barsic, Bruno, additional, Giannitsioti, Efthymia, additional, Hurley, John P., additional, Hannan, Margaret M., additional, and Park, Lawrence P., additional

Published
2019
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32. 2019 EACTS Expert Consensus on long-term mechanical circulatory support

Author

Potapov, Evgenij V, primary, Antonides, Christiaan, additional, Crespo-Leiro, Maria G, additional, Combes, Alain, additional, Färber, Gloria, additional, Hannan, Margaret M, additional, Kukucka, Marian, additional, de Jonge, Nicolaas, additional, Loforte, Antonio, additional, Lund, Lars H, additional, Mohacsi, Paul, additional, Morshuis, Michiel, additional, Netuka, Ivan, additional, Özbaran, Mustafa, additional, Pappalardo, Federico, additional, Scandroglio, Anna Mara, additional, Schweiger, Martin, additional, Tsui, Steven, additional, Zimpfer, Daniel, additional, and Gustafsson, Finn, additional

Published
2019
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33. 2019 EACTS Expert Consensus on long-term mechanical circulatory support

Author

Potapov, Evgenij V, Antonides, Christiaan, Crespo-Leiro, Maria G, Combes, Alain, Färber, Gloria, Hannan, Margaret M, Kukucka, Marian, de Jonge, Nicolaas, Loforte, Antonio, Lund, Lars H, Mohacsi, Paul, Morshuis, Michiel, Netuka, Ivan, Özbaran, Mustafa, Pappalardo, Federico, Scandroglio, Anna Mara, Schweiger, Martin, Tsui, Steven, Zimpfer, Daniel, Gustafsson, Finn, Potapov, Evgenij V, Antonides, Christiaan, Crespo-Leiro, Maria G, Combes, Alain, Färber, Gloria, Hannan, Margaret M, Kukucka, Marian, de Jonge, Nicolaas, Loforte, Antonio, Lund, Lars H, Mohacsi, Paul, Morshuis, Michiel, Netuka, Ivan, Özbaran, Mustafa, Pappalardo, Federico, Scandroglio, Anna Mara, Schweiger, Martin, Tsui, Steven, Zimpfer, Daniel, and Gustafsson, Finn

Published
2019

34. 2019 EACTS Expert Consensus on long-term mechanical circulatory support

Author

Circulatory Health, Team Medisch, Potapov, Evgenij V, Antonides, Christiaan, Crespo-Leiro, Maria G, Combes, Alain, Färber, Gloria, Hannan, Margaret M, Kukucka, Marian, de Jonge, Nicolaas, Loforte, Antonio, Lund, Lars H, Mohacsi, Paul, Morshuis, Michiel, Netuka, Ivan, Özbaran, Mustafa, Pappalardo, Federico, Scandroglio, Anna Mara, Schweiger, Martin, Tsui, Steven, Zimpfer, Daniel, Gustafsson, Finn, Circulatory Health, Team Medisch, Potapov, Evgenij V, Antonides, Christiaan, Crespo-Leiro, Maria G, Combes, Alain, Färber, Gloria, Hannan, Margaret M, Kukucka, Marian, de Jonge, Nicolaas, Loforte, Antonio, Lund, Lars H, Mohacsi, Paul, Morshuis, Michiel, Netuka, Ivan, Özbaran, Mustafa, Pappalardo, Federico, Scandroglio, Anna Mara, Schweiger, Martin, Tsui, Steven, Zimpfer, Daniel, and Gustafsson, Finn

Published
2019

35. 2019 EACTS Expert Consensus on long-term mechanical circulatory support

Author

Potapov, Evgenij V., Antonides, Christiaan, Crespo-Leiro, María Generosa, Combes, Alain, Färber, Gloria, Hannan, Margaret M., Kukucka, Marian, De Jonge, Nicolaas, Loforte, Antonio, Lund, Lars H., Mohacsi, Paul, Morshuis, Michiel, Netuka, Ivan, Özbaran, Mustafa, Pappalardo, Federico, Scandroglio, Anna Mara, Schweiger, Martin, Tsui, Steven, Zimpfer, Daniel, Gustafsson, Fin, Potapov, Evgenij V., Antonides, Christiaan, Crespo-Leiro, María Generosa, Combes, Alain, Färber, Gloria, Hannan, Margaret M., Kukucka, Marian, De Jonge, Nicolaas, Loforte, Antonio, Lund, Lars H., Mohacsi, Paul, Morshuis, Michiel, Netuka, Ivan, Özbaran, Mustafa, Pappalardo, Federico, Scandroglio, Anna Mara, Schweiger, Martin, Tsui, Steven, Zimpfer, Daniel, and Gustafsson, Fin

Abstract

[Abstract] Long-term mechanical circulatory support (LT-MCS) is an important treatment modality for patients with severe heart failure. Different devices are available, and many—sometimes contradictory—observations regarding patient selection, surgical techniques, perioperative management and follow-up have been published. With the growing expertise in this field, the European Association for Cardio-Thoracic Surgery (EACTS) recognized a need for a structured multidisciplinary consensus about the approach to patients with LT-MCS. However, the evidence published so far is insufficient to allow for generation of meaningful guidelines complying with EACTS requirements. Instead, the EACTS presents an expert opinion in the LT-MCS field. This expert opinion addresses patient evaluation and preoperative optimization as well as management of cardiac and non-cardiac comorbidities. Further, extensive operative implantation techniques are summarized and evaluated by leading experts, depending on both patient characteristics and device selection. The faculty recognized that postoperative management is multidisciplinary and includes aspects of intensive care unit stay, rehabilitation, ambulatory care, myocardial recovery and end-of-life care and mirrored this fact in this paper. Additionally, the opinions of experts on diagnosis and management of adverse events including bleeding, cerebrovascular accidents and device malfunction are presented. In this expert consensus, the evidence for the complete management from patient selection to end-of-life care is carefully reviewed with the aim of guiding clinicians in optimizing management of patients considered for or supported by an LT-MCS device.

Published
2019

36. Beta-Hemolytic Streptococcal Infective Endocarditis: Characteristics and Outcomes From a Large, Multinational Cohort.

Author

Hidalgo, Núria Fernández, Gharamti, Amal A, Aznar, María Luisa, Almirante, Benito, Yasmin, Mohamad, Fortes, Claudio Querido, Plesiat, Patrick, Doco-Lecompte, Thanh, Rizk, Hussein, Wray, Dannah, Lamas, Cristiane, Durante-Mangoni, Emanuele, Tattevin, Pierre, Snygg-Martin, Ulrika, Hannan, Margaret M, Chu, Vivian H, and Kanafani, Zeina A

Subjects
INFECTIVE endocarditis, CONGESTIVE heart failure, CONGENITAL heart disease, HOSPITAL mortality, ARTIFICIAL implants, DISEASE susceptibility
Abstract

Background Beta-hemolytic streptococci (BHS) are an uncommon cause of infective endocarditis (IE). The aim of this study was to describe the clinical features and outcomes of patients with BHS IE in a large multinational cohort and compare them with patients with viridans streptococcal IE. Methods The International Collaboration on Endocarditis Prospective Cohort Study (ICE-PCS) is a large multinational database that recruited patients with IE prospectively using a standardized data set. Sixty-four sites in 28 countries reported patients prospectively using a standard case report form developed by ICE collaborators. Results Among 1336 definite cases of streptococcal IE, 823 were caused by VGS and 147 by BHS. Patients with BHS IE had a lower prevalence of native valve (P <.005) and congenital heart disease predisposition (P =.002), but higher prevalence of implantable cardiac device predisposition (P <.005). Clinically, they were more likely to present acutely (P <.005) and with fever (P =.024). BHS IE was more likely to be complicated by stroke and other systemic emboli (P <.005). The overall in-hospital mortality of BHS IE was significantly higher than that of VGS IE (P =.001). In univariate analysis, variables associated with in-hospital mortality for BHS IE were age (odds ratio [OR], 1.044; P =.004), prosthetic valve IE (OR, 3.029; P =.022), congestive heart failure (OR, 2.513; P =.034), and stroke (OR, 3.198; P =.009). Conclusions BHS IE is characterized by an acute presentation and higher rate of stroke, systemic emboli, and in-hospital mortality than VGS IE. Implantable cardiac devices as a predisposing factor were more often found in BHS IE compared with VGS IE. [ABSTRACT FROM AUTHOR]

Published
2020
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38. The association between vegetation size and surgical treatment on 6-month mortality in left-sided infective endocarditis.

Author

Fosbøl, Emil L, Park, Lawrence P, Chu, Vivian H, Athan, Eugene, Delahaye, Francois, Freiberger, Tomas, Lamas, Cristiane, Miro, Jose M, Strahilevitz, Jacob, Tribouilloy, Christophe, Durante-Mangoni, Emanuele, Pericas, Juan M, Fernández-Hidalgo, Nuria, Nacinovich, Francisco, Rizk, Hussein, Barsic, Bruno, Giannitsioti, Efthymia, Hurley, John P, Hannan, Margaret M, and Wang, Andrew

Abstract

Aims In left-sided infective endocarditis (IE), a large vegetation >10 mm is associated with higher mortality, yet it is unknown whether surgery during the acute phase opposed to medical therapy is associated with improved survival. We assessed the association between surgery and 6-month mortality as related to vegetation size. Methods and results Patients with definite, left-sided IE (2008–2012) from The International Collaboration on Endocarditis prospective, multinational registry were included. We compared clinical characteristics and 6-month mortality (by Cox regression with inverse propensity of treatment weighting) between patients with vegetation size ≤10 mm vs. >10 mm in maximum length by surgical treatment strategy. A total of 1006 patients with left sided IE were included; 422 with a vegetation size ≤10 mm (median age 66.0 years, 33% women) and 584 (median age 58.4 years, 34% women) patients with a large vegetation >10 mm. Operative risk by STS-IE score was similar between groups. Embolic events occurred in 28.4% vs. 44.3% (P  < 0.001), respectively. Patients with a vegetation >10 mm was associated with higher 6-month mortality (25.1% vs. 19.4% for small vegetation, P  = 0.035). However, after propensity adjustment, the association with higher mortality persisted only in patients with a large vegetation >10 mm vs. ≤10 mm: hazard ratio (HR) 1.55 (1.27–1.90); but only in patients with large vegetation managed medically [HR 1.86 (1.48–2.34)] rather than surgically [HR 1.01 (0.69–1.49)]. Conclusion Left-sided IE with vegetation size >10 mm was associated with an increased mortality at 6 months in this observational study but was dependent on treatment strategy. For patients with large vegetation undergoing surgical treatment, survival was similar to patients with smaller vegetation size. [ABSTRACT FROM AUTHOR]

Published
2019
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39. Corrigendum to “association between the timing of surgery for complicated, left-sided infective endocarditis and survival”, American HeartJournal 2019, volume 210, April 2019, pages 108–116

Author

Wang, Andrew, Chu, Vivian H., Athan, Eugene, Delahaye, Francois, Freiberger, Tomas, Lamas, Cristiane, Miro, Jose M., Strahilevitz, Jacob, Tribouilloy, Christophe, Durante-Mangoni, Emanuele, Pericas, Juan M., Fernández-Hidalgo, Nuria, Nacinovich, Francisco, Barsic, Bruno, Giannitsioti, Efthymia, Hurley, John P., Hannan, Margaret M., and Park, Lawrence P.

Published
2019
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40. Validated Risk Score for Predicting 6‐Month Mortality in Infective Endocarditis

Author

Park, Lawrence P., primary, Chu, Vivian H., additional, Peterson, Gail, additional, Skoutelis, Athanasios, additional, Lejko‐Zupa, Tatjana, additional, Bouza, Emilio, additional, Tattevin, Pierre, additional, Habib, Gilbert, additional, Tan, Ren, additional, Gonzalez, Javier, additional, Altclas, Javier, additional, Edathodu, Jameela, additional, Fortes, Claudio Querido, additional, Siciliano, Rinaldo Focaccia, additional, Pachirat, Orathai, additional, Kanj, Souha, additional, Wang, Andrew, additional, Clara, Liliana, additional, Sanchez, Marisa, additional, Casabé, José, additional, Cortes, Claudia, additional, Nacinovich, Francisco, additional, Fernandez Oses, Pablo, additional, Ronderos, Ricardo, additional, Sucari, Adriana, additional, Thierer, Jorge, additional, Kogan, Silvia, additional, Spelman, Denis, additional, Athan, Eugene, additional, Harris, Owen, additional, Kennedy, Karina, additional, Gordon, David, additional, Papanicolas, Lito, additional, Korman, Tony, additional, Kotsanas, Despina, additional, Dever, Robyn, additional, Jones, Phillip, additional, Konecny, Pam, additional, Lawrence, Richard, additional, Rees, David, additional, Ryan, Suzanne, additional, Feneley, Michael P., additional, Harkness, John, additional, Post, Jeffrey, additional, Reinbott, Porl, additional, Gattringer, Rainer, additional, Wiesbauer, Franz, additional, Andrade, Adriana Ribas, additional, de Brito, Ana Cláudia Passos, additional, Guimarães, Armenio Costa, additional, Grinberg, Max, additional, Mansur, Alfredo José, additional, Strabelli, Tania Mara Varejao, additional, Vieira, Marcelo Luiz Campos, additional, de Medeiros Tranchesi, Regina Aparecida, additional, Paiva, Marcelo Goulart, additional, de Oliveira Ramos, Auristela, additional, Weksler, Clara, additional, Ferraiuoli, Giovanna, additional, Golebiovski, Wilma, additional, Lamas, Cristiane, additional, Karlowsky, James A., additional, Keynan, Yoav, additional, Morris, Andrew M., additional, Rubinstein, Ethan, additional, Jones, Sandra Braun, additional, Garcia, Patricia, additional, Fica, Alberto, additional, Mella, Rodrigo Montagna, additional, Fernandez, Ricardo, additional, Franco, Liliana, additional, Jaramillo, Astrid Natalia, additional, Barsic, Bruno, additional, Bukovski, Suzana, additional, Krajinovic, Vladimir, additional, Pangercic, Ana, additional, Rudez, Igor, additional, Vincelj, Josip, additional, Freiberger, Tomas, additional, Pol, Jiri, additional, Zaloudikova, Barbora, additional, Ashour, Zainab, additional, El Kholy, Amani, additional, Mishaal, Marwa, additional, Osama, Dina, additional, Rizk, Hussien, additional, Aissa, Neijla, additional, Alauzet, Corentine, additional, Alla, Francois, additional, Campagnac, Catherine, additional, Doco‐Lecompte, Thanh, additional, Selton‐Suty, Christine, additional, Casalta, Jean‐Paul, additional, Fournier, Pierre‐Edouard, additional, Raoult, Didier, additional, Thuny, Franck, additional, Delahaye, Francois, additional, Delahaye, Armelle, additional, Vandenesch, Francois, additional, Donal, Erwan, additional, Donnio, Pierre Yves, additional, Flecher, Erwan, additional, Michelet, Christian, additional, Revest, Matthieu, additional, Chevalier, Florent, additional, Jeu, Antoine, additional, Rémadi, Jean Paul, additional, Rusinaru, Dan, additional, Tribouilloy, Christophe, additional, Bernard, Yvette, additional, Chirouze, Catherine, additional, Hoen, Bruno, additional, Leroy, Joel, additional, Plesiat, Patrick, additional, Naber, Christoph, additional, Neuerburg, Carl, additional, Mazaheri, Bahram, additional, Athanasia, Sophia, additional, Deliolanis, Ioannis, additional, Giamarellou, Helen, additional, Thomas, Tsaganos, additional, Giannitsioti, Efthymia, additional, Mylona, Elena, additional, Paniara, Olga, additional, Papanicolaou, Konstantinos, additional, Pyros, John, additional, Papanikolaou, Konstantinos, additional, Sharma, Gautam, additional, Francis, Johnson, additional, Nair, Lathi, additional, Thomas, Vinod, additional, Venugopal, Krishnan, additional, Hannan, Margaret M., additional, Hurley, John P., additional, Cahan, Amos, additional, Gilon, Dan, additional, Israel, Sarah, additional, Korem, Maya, additional, Strahilevitz, Jacob, additional, Durante‐Mangoni, Emanuele, additional, Mattucci, Irene, additional, Pinto, Daniela, additional, Agrusta, Federica, additional, Senese, Alessandra, additional, Ragone, Enrico, additional, Utili, Riccardo, additional, Cecchi, Enrico, additional, De Rosa, Francesco, additional, Forno, Davide, additional, Imazio, Massimo, additional, Trinchero, Rita, additional, Grossi, Paolo, additional, Lattanzio, Mariangela, additional, Toniolo, Antonio, additional, Goglio, Antonio, additional, Raglio, Annibale, additional, Ravasio, Veronica, additional, Rizzi, Marco, additional, Suter, Fredy, additional, Carosi, Giampiero, additional, Magri, Silvia, additional, Signorini, Liana, additional, Kanafani, Zeina, additional, Kanj, Souha S., additional, Sharif‐Yakan, Ahmad, additional, Abidin, Imran, additional, Tamin, Syahidah Syed, additional, Martínez, Eduardo Rivera, additional, Soto Nieto, Gabriel Israel, additional, van der Meer, Jan T.M., additional, Chambers, Stephen, additional, Holland, David, additional, Morris, Arthur, additional, Raymond, Nigel, additional, Read, Kerry, additional, Murdoch, David R., additional, Dragulescu, Stefan, additional, Ionac, Adina, additional, Mornos, Cristian, additional, Butkevich, O.M., additional, Chipigina, Natalia, additional, Kirill, Ozerecky, additional, Vadim, Kulichenko, additional, Vinogradova, Tatiana, additional, Halim, Magid, additional, Liew, Yee‐Yun, additional, Tan, Ru‐San, additional, Logar, Mateja, additional, Mueller‐Premru, Manica, additional, Commerford, Patrick, additional, Commerford, Anita, additional, Deetlefs, Eduan, additional, Hansa, Cass, additional, Ntsekhe, Mpiko, additional, Almela, Manuel, additional, Armero, Yolanda, additional, Azqueta, Manuel, additional, Castañeda, Ximena, additional, Cervera, Carlos, additional, Falces, Carlos, additional, Garcia‐de‐la‐Maria, Cristina, additional, Fita, Guillermina, additional, Gatell, Jose M., additional, Heras, Magda, additional, Llopis, Jaime, additional, Marco, Francesc, additional, Mestres, Carlos A., additional, Miró, José M., additional, Moreno, Asuncion, additional, Ninot, Salvador, additional, Paré, Carlos, additional, Pericas, Juan M., additional, Ramirez, Jose, additional, Rovira, Irene, additional, Sitges, Marta, additional, Anguera, Ignasi, additional, Font, Bernat, additional, Guma, Joan Raimon, additional, Bermejo, Javier, additional, Garcia Fernández, Miguel Angel, additional, Gonzalez‐Ramallo, Victor, additional, Marín, Mercedes, additional, Muñoz, Patricia, additional, Pedromingo, Miguel, additional, Roda, Jorge, additional, Rodríguez‐Créixems, Marta, additional, Solis, Jorge, additional, Almirante, Benito, additional, Fernandez‐Hidalgo, Nuria, additional, Tornos, Pilar, additional, de Alarcón, Arístides, additional, Parra, Ricardo, additional, Alestig, Eric, additional, Johansson, Magnus, additional, Olaison, Lars, additional, Snygg‐Martin, Ulrika, additional, Pachirat, Pimchitra, additional, Pussadhamma, Burabha, additional, Senthong, Vichai, additional, Casey, Anna, additional, Elliott, Tom, additional, Lambert, Peter, additional, Watkin, Richard, additional, Eyton, Christina, additional, Klein, John L., additional, Bradley, Suzanne, additional, Kauffman, Carol, additional, Bedimo, Roger, additional, Corey, G. Ralph, additional, Crowley, Anna Lisa, additional, Douglas, Pamela, additional, Drew, Laura, additional, Fowler, Vance G., additional, Holland, Thomas, additional, Lalani, Tahaniyat, additional, Mudrick, Daniel, additional, Samad, Zaniab, additional, Sexton, Daniel, additional, Stryjewski, Martin, additional, Woods, Christopher W., additional, Lerakis, Stamatios, additional, Cantey, Robert, additional, Steed, Lisa, additional, Wray, Dannah, additional, Dickerman, Stuart A., additional, Bonilla, Hector, additional, DiPersio, Joseph, additional, Salstrom, Sara‐Jane, additional, Baddley, John, additional, Patel, Mukesh, additional, Stancoven, Amy, additional, Levine, Donald, additional, Riddle, Jonathan, additional, Rybak, Michael, additional, Cabell, Christopher H., additional, Baloch, Khaula, additional, Dixon, Christy C., additional, Harding, Tina, additional, Jones‐Richmond, Marian, additional, Sanderford, Bob, additional, Stafford, Judy, additional, Anstrom, Kevin, additional, Bayer, Arnold S., additional, Karchmer, A. W., additional, Sexton, Daniel J., additional, Chu, Vivian, additional, Durack, David T., additional, Eykyn, Susannah, additional, and Moreillon, Phillipe, additional

Published
2016
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42. Response to Letter Regarding Article, “Association Between Surgical Indications, Operative Risk, and Clinical Outcome in Infective Endocarditis: A Prospective Study From the International Collaboration on Endocarditis”

Author

Chu, Vivian H., primary, Park, Lawrence P., additional, Athan, Eugene, additional, Delahaye, Francois, additional, Freiberger, Tomas, additional, Lamas, Cristiane, additional, Miro, Jose M., additional, Mudrick, Daniel W., additional, Strahilevitz, Jacob, additional, Tribouilloy, Christophe, additional, Durante-Mangoni, Emanuele, additional, Pericas, Juan M., additional, Fernández-Hidalgo, Nuria, additional, Nacinovich, Francisco, additional, Rizk, Hussien, additional, Krajinovic, Vladimir, additional, Giannitsioti, Efthymia, additional, Hurley, John P., additional, Hannan, Margaret M., additional, and Wang, Andrew, additional

Published
2015
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43. Impact of Early Valve Surgery on Outcome of Staphylococcus aureus Prosthetic Valve Infective Endocarditis: Analysis in the International Collaboration of Endocarditis–Prospective Cohort Study.

Author

Chirouze, Catherine, Alla, François, Fowler, Vance G., Sexton, Daniel J., Corey, G. Ralph, Chu, Vivian H., Wang, Andrew, Erpelding, Marie-Line, Durante-Mangoni, Emanuele, Fernández-Hidalgo, Nuria, Giannitsioti, Efthymia, Hannan, Margaret M., Lejko-Zupanc, Tatjana, Miró, José M., Muñoz, Patricia, Murdoch, David R., Tattevin, Pierre, Tribouilloy, Christophe, and Hoen, Bruno

Subjects
STAPHYLOCOCCUS aureus infections, HEART valve surgery, TREATMENT of endocarditis, HEART valve prosthesis implantation, SURGICAL complications, DEATH rate, THERAPEUTICS
Abstract

Using appropriate analytical methods to examine data from the International Collaboration on Endocarditis–Prospective Cohort Study, we found that early valve surgery was not associated with reduced 1-year mortality in Staphylococcus aureus prosthetic valve infective endocarditis.Background. The impact of early valve surgery (EVS) on the outcome of Staphylococcus aureus (SA) prosthetic valve infective endocarditis (PVIE) is unresolved. The objective of this study was to evaluate the association between EVS, performed within the first 60 days of hospitalization, and outcome of SA PVIE within the International Collaboration on Endocarditis–Prospective Cohort Study.Methods. Participants were enrolled between June 2000 and December 2006. Cox proportional hazards modeling that included surgery as a time-dependent covariate and propensity adjustment for likelihood to receive cardiac surgery was used to evaluate the impact of EVS and 1-year all-cause mortality on patients with definite left-sided S. aureus PVIE and no history of injection drug use.Results. EVS was performed in 74 of the 168 (44.3%) patients. One-year mortality was significantly higher among patients with S. aureus PVIE than in patients with non–S. aureus PVIE (48.2% vs 32.9%; P = .003). Staphylococcus aureus PVIE patients who underwent EVS had a significantly lower 1-year mortality rate (33.8% vs 59.1%; P = .001). In multivariate, propensity-adjusted models, EVS was not associated with 1-year mortality (risk ratio, 0.67 [95% confidence interval, .39–1.15]; P = .15).Conclusions. In this prospective, multinational cohort of patients with S. aureus PVIE, EVS was not associated with reduced 1-year mortality. The decision to pursue EVS should be individualized for each patient, based upon infection-specific characteristics rather than solely upon the microbiology of the infection causing PVIE. [ABSTRACT FROM PUBLISHER]

Published
2015

44. A 2‐year Review of the Diagnostic Performance of Serum and Bronchoalveolar Lavage Galactomannan Testing in Lung Transplant Recipients in a National Heart and Lung Transplant Centre.

Author

O'Donnell, Clare, Lynch, Breda, O'Sullivan, Louise, Killarney, Assumpta, Murray, Michelle, Riddell, Peter, and Hannan, Margaret M.

Subjects
*PULMONARY aspergillosis, *HEART transplant recipients, *LUNG transplantation, *HEART transplantation, *BRONCHOALVEOLAR lavage
Abstract

ABSTRACT Background Methods Results Conclusion The 2015 International Society for Heart and Lung Transplant (ISHLT) fungal guidelines recommend the use of bronchoalveolar lavage (BAL) galactomannan over serum galactomannan for the diagnosis of invasive aspergillosis (IA) in lung transplant (LTx) recipients, based on limited evidence. Galactomannan testing is costly.A single‐center, retrospective cohort study reviewing all 814 serum and BAL galactomannan samples received from 184 LTx recipients in our center between 2021 and 2022 and assessing their diagnostic performance in the diagnosis of IA.Over the study period, 394 serum galactomannan samples were received from 144 patients and 420 BAL galactomannan samples from 143 patients. Using a cut‐off of ≥ 1.0 for BAL galactomannan, the sensitivity and specificity were 65.9% and 98.4%, respectively. In total, 30 patients had positive BAL galactomannan. Antifungal therapy was commenced or continued in 29 of these patients either as targeted or pre‐emptive treatment. Using a cut‐off of ≥ 0.5 for serum galactomannan, the sensitivity and specificity were 9.7% and 99.7%, respectively. In total, four patients had a positive serum galactomannan. All four patients were either already on antifungal treatment for IA or were started before the serum galactomannan result was available, supported by laboratory, clinical, and radiological findings. A positive serum galactomannan was used to monitor treatment response in one patient.Serum galactomannan is not a valuable test in the diagnosis of IA in our LTx recipients, is costly, and does not remove the need for bronchoscopy and BAL galactomannan. This supports the ISHLT recommendation. [ABSTRACT FROM AUTHOR]

Published
2024
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45. Beta-Hemolytic Streptococcal Infective Endocarditis: Characteristics and Outcomes From a Large, Multinational Cohort

Author

Vivian H. Chu, Zeina A. Kanafani, Pierre Tattevin, Emanuele Durante-Mangoni, Benito Almirante, Patrick Plésiat, Mohamad Yasmin, Núria Fernández Hidalgo, Amal A Gharamti, Cristiane da Cruz Lamas, Thanh Doco-Lecompte, Hussein Rizk, María Luisa Aznar, Margaret M. Hannan, Claudio Querido Fortes, Ulrika Snygg-Martin, Dannah Wray, Servei de Medicina Intensiva, Hospital Universitari Vall d'Hebron, Institut de Recerca Vall d'Hebron, Barcelona, American University of Beirut Faculty of Medicine and Medical Center (AUB), Louis Stokes Cleveland Veterans Affairs Medical Center, Universidade Federal do Estado do Rio de Janeiro (UNIRIO), Université de Franche-Comté (UFC), Université Bourgogne Franche-Comté [COMUE] (UBFC), Geneva University Hospitals and Geneva University, Cairo University, Medical University of South Carolina [Charleston] (MUSC), University of the Study of Campania Luigi Vanvitelli, Université de Rennes (UR), University of Gothenburg (GU), Mater Misericordiae University Hospital (The Mater Hospital), Duke University Medical Center, Fernández Hidalgo, Núria, Gharamti, Amal A, Aznar, María Luisa, Almirante, Benito, Yasmin, Mohamad, Fortes, Claudio Querido, Plesiat, Patrick, Doco-Lecompte, Thanh, Rizk, Hussein, Wray, Dannah, Lamas, Cristiane, Durante-Mangoni, Emanuele, Tattevin, Pierre, Snygg-Martin, Ulrika, Hannan, Margaret M, Chu, Vivian H, Kanafani, Zeina A, Université de Rennes (UNIV-RENNES), and Mater Misericordiae University Hospital [Dublin] (The Mater Hospital)

Subjects
0301 basic medicine, medicine.medical_specialty, 030106 microbiology, cardiac devices, Hospital mortality, medicine.disease_cause, 03 medical and health sciences, beta-hemolytic streptococci, Bacterial endocarditis, medicine, Major Article, Endocarditis, Gynecology, International Collaboration on Endocarditi, business.industry, Streptococcus, infective endocarditis, cardiac device, medicine.disease, 3. Good health, 030104 developmental biology, Infectious Diseases, Beta-hemolytic, AcademicSubjects/MED00290, congestive heart failure, [SDV.MP]Life Sciences [q-bio]/Microbiology and Parasitology, Oncology, Infective endocarditis, Cohort, International Collaboration on Endocarditis, Beta-hemolytic streptococcus, business
Abstract

Background Beta-hemolytic streptococci (BHS) are an uncommon cause of infective endocarditis (IE). The aim of this study was to describe the clinical features and outcomes of patients with BHS IE in a large multinational cohort and compare them with patients with viridans streptococcal IE. Methods The International Collaboration on Endocarditis Prospective Cohort Study (ICE-PCS) is a large multinational database that recruited patients with IE prospectively using a standardized data set. Sixty-four sites in 28 countries reported patients prospectively using a standard case report form developed by ICE collaborators. Results Among 1336 definite cases of streptococcal IE, 823 were caused by VGS and 147 by BHS. Patients with BHS IE had a lower prevalence of native valve (P < .005) and congenital heart disease predisposition (P = .002), but higher prevalence of implantable cardiac device predisposition (P < .005). Clinically, they were more likely to present acutely (P < .005) and with fever (P = .024). BHS IE was more likely to be complicated by stroke and other systemic emboli (P < .005). The overall in-hospital mortality of BHS IE was significantly higher than that of VGS IE (P = .001). In univariate analysis, variables associated with in-hospital mortality for BHS IE were age (odds ratio [OR], 1.044; P = .004), prosthetic valve IE (OR, 3.029; P = .022), congestive heart failure (OR, 2.513; P = .034), and stroke (OR, 3.198; P = .009). Conclusions BHS IE is characterized by an acute presentation and higher rate of stroke, systemic emboli, and in-hospital mortality than VGS IE. Implantable cardiac devices as a predisposing factor were more often found in BHS IE compared with VGS IE.

Published
2020
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46. Association between the timing of surgery for complicated, left-sided infective endocarditis and survival

Author

Cristiane da Cruz Lamas, Juan M. Pericàs, Andrew Wang, Emanuele Durante-Mangoni, Francisco Nacinovich, John P. Hurley, Tomáš Freiberger, Margaret M. Hannan, José M. Miró, Bruno Baršić, François Delahaye, Jacob Strahilevitz, Lawrence P. Park, Christophe Tribouilloy, Nuria Fernández-Hidalgo, Efthymia Giannitsioti, Vivian H. Chu, Eugene Athan, Wang, Andrew, Chu, Vivian H., Athan, Eugene, Delahaye, Francoi, Freiberger, Toma, Lamas, Cristiane, Miro, Jose M., Strahilevitz, Jacob, Tribouilloy, Christophe, Durante-Mangoni, Emanuele, Pericas, Juan M., Fernández-Hidalgo, Nuria, Nacinovich, Francisco, Barsic, Bruno, Giannitsioti, Efthymia, Hurley, John P., Hannan, Margaret M., and Park, Lawrence P.

Subjects
Adult, Male, Patient Transfer, medicine.medical_specialty, Staphylococcus aureus, 030204 cardiovascular system & hematology, Time-to-Treatment, 03 medical and health sciences, 0302 clinical medicine, Interquartile range, Risk Factors, medicine, Endocarditis, Humans, 030212 general & internal medicine, Prospective Studies, Prospective cohort study, Abscess, Propensity Score, Aged, Proportional Hazards Models, Heart Failure, business.industry, Proportional hazards model, Endocarditis, Bacterial, Middle Aged, Staphylococcal Infections, medicine.disease, Surgery, Cardiac surgery, Hospitalization, Heart failure, Infective endocarditis, Surgical Procedures, Operative, Acute Disease, Female, business, Cardiology and Cardiovascular Medicine
Abstract

Background: In patients with active infective endocarditis (IE), the relationship between timing of surgery and survival is uncertain. The objective was to evaluate clinical characteristics associated with timing of surgery and the association between surgical timing and 6-month survival in complicated, left-sided IE. Methods: In a prospective, multicenter, observational registry (The International Collaboration on Endocarditis-PLUS, registry from 2008 to 2012), clinical factors associated with timing of surgery during the index hospitalization were determined among 485 adult patients with definite, complicated, left-sided IE who underwent cardiac surgery during their index hospitalization. The relationship between early surgical intervention (

Published
2019

47. Response to Letter Regarding Article, 'Association Between Surgical Indications, Operative Risk, and Clinical Outcome in Infective Endocarditis: A Prospective Study From the International Collaboration on Endocarditis'

Author

Nuria Fernández-Hidalgo, Andrew Wang, Emanuele Durante-Mangoni, Eugene Athan, Vivian H. Chu, Francisco Nacinovich, Lawrence P. Park, Tomáš Freiberger, Vladimir Krajinović, Daniel W. Mudrick, Cristiane da Cruz Lamas, Efthymia Giannitsioti, Jacob Strahilevitz, John P. Hurley, Margaret M. Hannan, Christophe Tribouilloy, Hussien Rizk, Juan M. Pericàs, François Delahaye, José M. Miró, Chu, Vivian H, Park, Lawrence P., Athan, Eugene, Delahaye, Francoi, Freiberger, Toma, Lamas, Cristiane, Miro, Jose M., Mudrick, Daniel W., Strahilevitz, Jacob, Tribouilloy, Christophe, DURANTE MANGONI, Emanuele, Pericas, Juan M., Fernández Hidalgo, Nuria, Nacinovich, Francisco, Rizk, Hussien, Krajinovic, Vladimir, Giannitsioti, Efthymia, Hurley, John P., Hannan, Margaret M., and Wang, Andrew

Subjects
Selection bias, Male, medicine.medical_specialty, Endocarditis, business.industry, media_common.quotation_subject, MEDLINE, medicine.disease, Outcome (game theory), Physiology (medical), Infective endocarditis, medicine, Humans, Female, Endocarditi, Operative risk, Cardiology and Cardiovascular Medicine, Association (psychology), Intensive care medicine, business, Prospective cohort study, Human, media_common
Abstract

We appreciate the thoughtful comments of Drs Almonedro-Delia, Galvez-Acebal, and Rodriguez-Bano regarding our recent publication, “Association Between Surgical Indications, Operative Risk, and Clinical Outcome in Infective Endocarditis: a Prospective Study From the International Collaboration on Endocarditis.”1 These authors raise important issues for evaluating the impact of surgery on patient outcomes, particularly survival. We strongly agree that treatment selection bias and survivor bias are major issues when evaluating the impact of surgery on mortality and that the use of appropriate statistical methodologies is necessary to quantify an unbiased and causal association of the effect of surgical treatment on outcome. In our previous studies on …

Published
2015

48. Near-fatal mucormycosis post-double lung transplant presenting as uncontrolled upper gastrointestinal haemorrhage.

Author

O'Connor C, Farrell C, Fabre A, Eaton D, Redmond K, McSharry DG, Conneely JB, Shields CJ, Egan JJ, and Hannan MM

Abstract

Invasive fungal infections in immunosuppressed transplant patients are associated with significant morbidity and mortality. We present a case of splenic mucormycosis post-double lung transplant, presenting as uncontrolled near-fatal upper gastrointestinal haemorrhage, to remind clinicians of the need to consider pre-transplant invasive fungal infection risk factors if an unexpected fungal infection arises in the post-transplant period. This case also highlights the valuable contribution of molecular technology for fungal identification but also the need for clinical correlation.

Published
2018
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