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Your search keyword '"Guimarães, Jorge Almeida"' showing total 24 results
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24 results on '"Guimarães, Jorge Almeida"'

1. Metarhizium anisopliae E6 secretome reveals molecular players in host specificity and toxicity linked to cattle tick infection

Author

de Oliveira, Laura Rascovetzki Saciloto, Broetto, Leonardo, Alves, Camila Innocente, da Rosa, Rafael Lopes, Alves, Yohana Porto Calegari, da Silva, Rodrigo Campos, Berger, Markus, Macedo, Alexandre José, Dalberto, Pedro Ferrari, Bizarro, Cristiano Valim, Guimarães, Jorge Almeida, Yates, John R., Santi, Lucélia, and Beys-da-Silva, Walter Orlando

Published
2023
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6. Metarhizium anisopliae E6 secretome reveals molecular players in host specificity and toxicity linked to cattle tick infection

Author

Saciloto-de-Oliveira, Laura Rascovetzki, primary, Broetto, Leonardo, additional, Alves, Camila Innocente, additional, da Rosa, Rafael Lopes, additional, Calegari Alves, Yohana Porto, additional, da Silva, Rodrigo Campos, additional, Berger, Markus, additional, Macedo, Alexandre José, additional, Dalberto, Pedro Ferrari, additional, Bizarro, Cristiano Valim, additional, Guimarães, Jorge Almeida, additional, Yates, John R., additional, Santi, Lucélia, additional, and Beys-da-Silva, Walter Orlando, additional

Published
2023
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9. The role of glial cells in Zika virus‐induced neurodegeneration

Author

Quincozes‐Santos, André, primary, Bobermin, Larissa Daniele, additional, Costa, Naithan Ludian Fernandes, additional, Thomaz, Natalie K., additional, Almeida, Rômulo Rodrigo de Souza, additional, Beys‐da‐Silva, Walter O., additional, Santi, Lucélia, additional, Rosa, Rafael L., additional, Capra, Daniela, additional, Coelho‐Aguiar, Juliana M., additional, DosSantos, Marcos Fabio, additional, Heringer, Manoela, additional, Cirne‐Lima, Elizabeth O., additional, Guimarães, Jorge Almeida, additional, Schuler‐Faccini, Lavínia, additional, Gonçalves, Carlos‐Alberto, additional, Moura‐Neto, Vivaldo, additional, and Souza, Diogo Onofre, additional

Published
2023
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11. In Vitro and in Vivo Anti-Inflammatory and Anticoagulant Activities of Myrciaria Plinioides D. Legrand Ethanol Leaf Extract

Author

Marmitt, Diorge Jônatas, primary, Bitencourt, Shanna, additional, Coura, Chistiane Oliveira, additional, Berger, Markus, additional, Faleiro, Dalana, additional, Kich, Débora Mara, additional, Caye, Bruna, additional, Immich, Sheila Mariele, additional, Frota, Annyta Fernandes, additional, Beys-da-Silva, Walter O., additional, Guimarães, Jorge Almeida, additional, Benevides, Norma Maria Barros, additional, Laufer, Stefan, additional, and Goettert, Márcia Inês, additional

Published
2021
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14. SARSCOVIDB—A New Platform for the Analysis of the Molecular Impact of SARS-CoV-2 Viral Infection

Author

da Rosa, Rafael Lopes, primary, Yang, Tung Sheng, additional, Tureta, Emanuela Fernanda, additional, de Oliveira, Laura Rascovetzki Saciloto, additional, Moraes, Amanda Naiara Silva, additional, Tatara, Juliana Miranda, additional, Costa, Renata Pereira, additional, Borges, Júlia Spier, additional, Alves, Camila Innocente, additional, Berger, Markus, additional, Guimarães, Jorge Almeida, additional, Santi, Lucélia, additional, and Beys-da-Silva, Walter Orlando, additional

Published
2021
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17. Renal and vascular effects of kallikrein inhibition in a model of Lonomia obliqua venom-induced acute kidney injury

Author

Berger, Markus, primary, de Moraes, João Alfredo, additional, Beys-da-Silva, Walter Orlando, additional, Santi, Lucélia, additional, Terraciano, Paula Barros, additional, Driemeier, David, additional, Cirne-Lima, Elizabeth Obino, additional, Passos, Eduardo Pandolfi, additional, Vieira, Maria Aparecida Ribeiro, additional, Barja-Fidalgo, Thereza Christina, additional, and Guimarães, Jorge Almeida, additional

Published
2019
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20. ZIKA Virus and Neuroscience: the Need for a Translational Collaboration

Author

Schuler-Faccini, Lavínia, primary, Roehe, Paulo, additional, Zimmer, Eduardo R., additional, Quincozes-Santos, André, additional, de Assis, Adriano M., additional, Lima, Elizabeth Obino Cirne, additional, Guimarães, Jorge Almeida, additional, Victora, Cesar, additional, Neto, Vivaldo Moura, additional, and Souza, Diogo O., additional

Published
2017
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24. Effects of Lonomia obliqua Venom on Vascular Smooth Muscle Cells: Contribution of NADPH Oxidase-Derived Reactive Oxygen Species.

Author

Moraes, João Alfredo, Rodrigues, Genilson, Nascimento-Silva, Vany, Renovato-Martins, Mariana, Berger, Markus, Guimarães, Jorge Almeida, and Barja-Fidalgo, Christina

Subjects
VENOM, CATERPILLARS, MUSCLE cells, REACTIVE oxygen species, BLOOD vessels, NADPH oxidase
Abstract

Envenomation caused by human contact with the caterpillar Lonomia is characterized by deleterious effects on coagulation and patency of blood vessels. The cellular effects induced by Lonomia obliqua venom highlights its capacity to activate endothelial cells, leading to a proinflammatory phenotype. Having more knowledge about the mechanisms involved in envenomation may contribute to better treatment. We aimed to evaluate the effects of Lonomia obliqua caterpillar bristle extract (LOCBE) on vascular smooth muscle cells (VSMC).We observed that LOCBE induced VSMC migration, which was preceded by alterations in actin cytoskeleton dynamics and Focal Adhesion Kinase activation. LOCBE also induced Extracellular Signal-Regulated Kinase (ERK) phosphorylation in VSMC, and the inhibition of this pathway impaired cell proliferation. Stimulation of VSMC with LOCBE triggered reactive oxygen species (ROS) production through the activation of NADPH oxidase. The rapid increase in these ROS further induced mitochondrial ROS production, however only NADPH oxidase-derived ROS were involved in ERK activation in VSMC. We that demonstrated the chemotactic and proliferative effects of LOCBE on VSMC were dependent on ROS production, mainly through NADPH oxidase. Together, the data show that Lonomia obliqua venom can interact with and activate VSMC. These effects rely on ROS production, suggesting new potential targets for treatment against vascular damage during envenomation. [ABSTRACT FROM AUTHOR]

Published
2017
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