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99 results on '"Guan MX"'

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1. Transcriptome-Based Analysis Reveals Therapeutic Effects of Resveratrol on Endometriosis in aRat Model

2. Mutation of CRYAB encoding a conserved mitochondrial chaperone and anti-apoptotic protein causes hereditary optic atrophy.

3. Mitochondrial tRNA Glu 14693A > G Mutation, an "Enhancer" to the Phenotypic Expression of Leber's Hereditary Optic Neuropathy.

4. SpliceTransformer predicts tissue-specific splicing linked to human diseases.

5. Deafness-associated tRNA Phe mutation impaired mitochondrial and cellular integrity.

6. Deficient tRNA posttranscription modification dysregulated the mitochondrial quality controls and apoptosis.

7. Induced pluripotent stem cells: ex vivo models for human diseases due to mitochondrial DNA mutations.

8. Giant acceleration of polaron transport by ultrafast laser-induced coherent phonons.

9. Optimized allotopic expression of mitochondrial ND6 transgene restored complex I and apoptosis deficiencies caused by LHON-linked ND6 14484T > C mutation.

10. cdh23 affects congenital hearing loss through regulating purine metabolism.

12. Nuclear modifier YARS2 allele correction restored retinal ganglion cells-specific deficiencies in Leber's hereditary optic neuropathy.

13. Emerging functions of mitochondria-encoded noncoding RNAs.

14. Abnormal morphology and function in retinal ganglion cells derived from patients-specific iPSCs generated from individuals with Leber's hereditary optic neuropathy.

15. Super-resolved time-frequency measurements of coupled phonon dynamics in a 2D quantum material.

16. Exportin 4 depletion leads to nuclear accumulation of a subset of circular RNAs.

17. Leber's hereditary optic neuropathy-associated ND6 14484T > C mutation caused pleiotropic effects on the complex I, RNA homeostasis, apoptosis and mitophagy.

18. Genetic correction of TRMU allele restored the mitochondrial dysfunction-induced deficiencies in iPSCs-derived hair cells of hearing-impaired patients.

19. Human TRUB1 is a highly conserved pseudouridine synthase responsible for the formation of Ψ55 in mitochondrial tRNAAsn, tRNAGln, tRNAGlu and tRNAPro.

20. A deafness-associated mitochondrial DNA mutation caused pleiotropic effects on DNA replication and tRNA metabolism.

21. Mitochondrial tRNA variants in 811 Chinese probands with Leber's hereditary optic neuropathy.

22. Heteroplasmic and homoplasmic m.616T>C in mitochondria tRNAPhe promote isolated chronic kidney disease and hyperuricemia.

23. Mechanistic insights into multiple-step transport of mitochondrial ADP/ATP carrier.

24. Investigating the Broad Matrix-Gate Network in the Mitochondrial ADP/ATP Carrier through Molecular Dynamics Simulations.

25. Optical Control of Multistage Phase Transition via Phonon Coupling in MoTe_{2}.

26. FARS2 deficiency in Drosophila reveals the developmental delay and seizure manifested by aberrant mitochondrial tRNA metabolism.

27. Tissue-specific expression atlas of murine mitochondrial tRNAs.

28. Assocation Between Leber's Hereditary Optic Neuropathy and MT-ND1 3460G>A Mutation-Induced Alterations in Mitochondrial Function, Apoptosis, and Mitophagy.

29. Mechanistic insights into mitochondrial tRNA Ala 3'-end metabolism deficiency.

30. Leber's Hereditary Optic Neuropathy Arising From the Synergy Between ND1 3635G>A Mutation and Mitochondrial YARS2 Mutations.

31. Ablation of Mto1 in zebrafish exhibited hypertrophic cardiomyopathy manifested by mitochondrion RNA maturation deficiency.

32. Manipulating Weyl quasiparticles by orbital-selective photoexcitation in WTe 2 .

33. A deafness-associated tRNA mutation caused pleiotropic effects on the m1G37 modification, processing, stability and aminoacylation of tRNAIle and mitochondrial translation.

34. An animal model for mitochondrial tyrosyl-tRNA synthetase deficiency reveals links between oxidative phosphorylation and retinal function.

35. Mutations of MAP1B encoding a microtubule-associated phosphoprotein cause sensorineural hearing loss.

36. Photosensitive tyrosine analogues unravel site-dependent phosphorylation in TrkA initiated MAPK/ERK signaling.

37. Asymmetrical effects of deafness-associated mitochondrial DNA 7516delA mutation on the processing of RNAs in the H-strand and L-strand polycistronic transcripts.

38. Complex I mutations synergize to worsen the phenotypic expression of Leber's hereditary optic neuropathy.

39. PRICKLE3 linked to ATPase biogenesis manifested Leber's hereditary optic neuropathy.

40. NEAT1 knockdown suppresses endothelial cell proliferation and induces apoptosis by regulating miR‑638/AKT/mTOR signaling in atherosclerosis.

41. Mitochondrial tRNA mutations in 887 Chinese subjects with hearing loss.

42. LINC00511 accelerates the proliferation of cardiomyocytes after myocardial ischemia/reperfusion injury by absorbing miRNA-515-5p.

43. Overexpression of mitochondrial histidyl-tRNA synthetase restores mitochondrial dysfunction caused by a deafness-associated tRNA His mutation.

44. Ultrafast charge ordering by self-amplified exciton-phonon dynamics in TiSe 2 .

45. Contribution of a mitochondrial tyrosyl-tRNA synthetase mutation to the phenotypic expression of the deafness-associated tRNA Ser(UCN) 7511A>G mutation.

46. Association of MTHFR C677T polymorphism and type 2 diabetes mellitus (T2DM) susceptibility.

47. Hypertension-associated mitochondrial DNA 4401A>G mutation caused the aberrant processing of tRNAMet, all 8 tRNAs and ND6 mRNA in the light-strand transcript.

48. Frequency and spectrum of MT-TT variants associated with Leber's hereditary optic neuropathy in a Chinese cohort of subjects.

49. Molecular dynamics simulations on apo ADP/ATP carrier shed new lights on the featured motif of the mitochondrial carriers.

50. Deletion of Gtpbp3 in zebrafish revealed the hypertrophic cardiomyopathy manifested by aberrant mitochondrial tRNA metabolism.

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