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5. Pulmonale Hypertonie bei Erwachsenen mit angeborenen Herzfehlern im Lichte der 2022-ESC-PAH-Leitlinien

Author

Kaemmerer, Harald, additional, Diller, Gerhard Paul, additional, Achenbach, Stephan, additional, Dähnert, Ingo, additional, Eichstaedt, Christina A., additional, Eicken, Andreas, additional, Freiberger, Annika, additional, Freilinger, Sebastian, additional, Geiger, Ralf, additional, Gorenflo, Matthias, additional, Grünig, Ekkehard, additional, Hager, Alfred, additional, Huntgeburth, Michael, additional, Kaemmerer-Suleiman, Ann-Sophie, additional, Kozlik-Feldmann, Rainer, additional, Lammers, Astrid E., additional, Nagdyman, Nicole, additional, Michel, Sebastian, additional, Schmidt, Kai Helge, additional, Uebing, Anselm, additional, von Scheidt, Fabian, additional, and Apitz, Christian, additional

Published
2024
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6. PATHFINDER-CHD: prospective registry on adults with congenital heart disease, abnormal ventricular function, and/or heart failure as a foundation for establishing rehabilitative, prehabilitative, preventive, and health-promoting measures: rationale, aims, design and methods

Author

Freilinger, Sebastian, primary, Kaemmerer, Harald, additional, Pittrow, Robert D., additional, Achenbach, Stefan, additional, Baldus, Stefan, additional, Dewald, Oliver, additional, Ewert, Peter, additional, Freiberger, Annika, additional, Gorenflo, Matthias, additional, Harig, Frank, additional, Hohmann, Christopher, additional, Holdenrieder, Stefan, additional, Hörer, Jürgen, additional, Huntgeburth, Michael, additional, Hübler, Michael, additional, Kohls, Niko, additional, Klawonn, Frank, additional, Kozlik-Feldmann, Rainer, additional, Kaulitz, Renate, additional, Loßnitzer, Dirk, additional, Mellert, Friedrich, additional, Nagdyman, Nicole, additional, Nordmeyer, Johannes, additional, Pittrow, Benjamin A., additional, Pittrow, Leonard B., additional, Rickers, Carsten, additional, Rosenkranz, Stefan, additional, Schelling, Jörg, additional, Sinning, Christoph, additional, Suleiman, Mathieu N., additional, von Kodolitsch, Yskert, additional, von Scheidt, Fabian, additional, and Kaemmerer-Suleiman, Ann-Sophie, additional

Published
2024
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8. Idiopathic pulmonary arterial hypertension phenotypes determined by cluster analysis from the COMPERA registry

Author

Hoeper, Marius M., Pausch, Christine, Grünig, Ekkehard, Klose, Hans, Staehler, Gerd, Huscher, Doerte, Pittrow, David, Olsson, Karen M., Vizza, Carmine Dario, Gall, Henning, Benjamin, Nicola, Distler, Oliver, Opitz, Christian, Gibbs, J. Simon R., Delcroix, Marion, Ghofrani, H. Ardeschir, Rosenkranz, Stephan, Ewert, Ralf, Kaemmerer, Harald, Lange, Tobias J., Kabitz, Hans-Joachim, Skowasch, Dirk, Skride, Andris, Jureviciene, Elena, Paleviciute, Egle, Miliauskas, Skaidrius, Claussen, Martin, Behr, Juergen, Milger, Katrin, Halank, Michael, Wilkens, Heinrike, Wirtz, Hubert, Pfeuffer-Jovic, Elena, Harbaum, Lars, Scholtz, Werner, Dumitrescu, Daniel, Bruch, Leonhard, Coghlan, Gerry, Neurohr, Claus, Tsangaris, Iraklis, Gorenflo, Matthias, Scelsi, Laura, Vonk-Noordegraaf, Anton, Ulrich, Silvia, and Held, Matthias

Published
2020
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12. Long‐term use of everolimus for refractory arrhythmia in a child with tuberous sclerosis complex.

Author

Hofmann, Christoph, Syrbe, Steffen, Hebe, Joachim, Kreft, Jannis, Stark, Sebastian, Milde, Till, Völkers, Mirko, Hoffmann, Georg Friedrich, Gorenflo, Matthias, and Kovacevic, Alexander

Abstract

Tuberous sclerosis complex is associated with the occurrence of cardiac rhabdomyomas that may result in life‐threatening arrhythmia unresponsive to standard antiarrhythmic therapy. We report the case of an infant with multiple cardiac rhabdomyomas who developed severe refractory supraventricular tachycardia (SVT) that was successfully treated with everolimus. Pharmacological mTOR inhibition rapidly improved arrhythmia within few weeks after treatment initiation and correlated with a reduction in tumor size. Intermediate attempts to discontinue everolimus resulted in rhabdomyoma size rebound and recurrence of arrhythmic episodes, which resolved on resumption of therapy. While everolimus treatment led to successful control of arrhythmia in the first years of life, episodes of SVT reoccurred at the age of 6 years. Electrophysiologic testing confirmed an accessory pathway that was successfully ablated, resulting in freedom of arrhythmic events. In summary we present an in‐depth evaluation of the long‐term use of everolimus in a child with TSC‐associated SVT, including the correlation between drug use and arrhythmia outcome. This case report provides important information on the safety and efficacy of an mTOR inhibitor for the treatment of a potentially life‐threatening cardiac disease manifestation in TSC for which the optimal treatment strategy is still not well established. [ABSTRACT FROM AUTHOR]

Published
2024
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13. Cardiomyopathies in children and adolescents: aetiology, management, and outcomes in the European Society of Cardiology EURObservational Research Programme Cardiomyopathy and Myocarditis Registry.

Author

Kaski, Juan Pablo, Norrish, Gabrielle, Blanes, Juan Ramon Gimeno, Charron, Philippe, Elliott, Perry, Tavazzi, Luigi, Tendera, Michal, Laroche, Cécile, Maggioni, Aldo P, Baban, Anwar, Khraiche, Diala, Ziolkowska, Lidia, Limongelli, Giuseppe, Ojala, Tiina, Gorenflo, Matthias, Anastasakis, Aris, Mostafa, Shaimaa, Caforio, Alida L P, and Investigators, the EORP Paediatric Cardiomyopathy Registry

Subjects
ARRHYTHMOGENIC right ventricular dysplasia, CARDIAC research, MYOCARDITIS, CARDIOMYOPATHIES, ETIOLOGY of diseases, GENETIC disorders
Abstract

Background and Aims Childhood-onset cardiomyopathies are rare and poorly characterized. This study examined the baseline characteristics and 1-year follow-up of children with cardiomyopathy in the first European Cardiomyopathy Registry. Methods Prospective data were collected on individuals aged 1–<18 years enrolled in the European Society of Cardiology EURObservational Research Programme Cardiomyopathy and Myocarditis long-term registry (June 2014–December 2016). Results A total of 633 individuals aged ≤18 years with hypertrophic [HCM; n = 388 (61.3%)], dilated [DCM; n = 206 (32.5%)], restrictive [RCM; n = 28 (4.4%)], and arrhythmogenic right ventricular cardiomyopathy [ARVC; n = 11 (1.7%)] were enrolled by 23 referral centres in 14 countries. Median age at diagnosis was 4.0 [interquartile range (IQR) 0–10] years, and there was a male predominance [ n = 372 (58.8%)] across all subtypes, with the exception of DCM diagnosed <10 years of age; 621 (98.1%) patients were receiving cardiac medication and 80 (12.6%) had an implantable cardioverter-defibrillator. A total of 253 patients (253/535, 47.3%) had familial disease. Genetic testing was performed in 414 (67.8%) patients with a pathogenic or likely pathogenic variant reported in 250 (60.4%). Rare disease phenocopies were reported in 177 patients (28.0%) and were most frequent in patients under 10 years [142 (30.9%) vs. 35 (19.6%); P =.003]. Over a median follow-up of 12.5 months (IQR 11.3–15.3 months), 18 patients (3.3%) died [HCM n = 9 (2.6%), DCM n = 5 (3.0%), RCM n = 4 (16.0%)]. Heart failure events were most frequent in RCM patients (36.0%). Conclusions The findings confirm the heterogeneous aetiology of childhood cardiomyopathies and show a high frequency of familial disease. Outcomes differed by cardiomyopathy subtype, highlighting a need for disease-specific evaluation and treatment. [ABSTRACT FROM AUTHOR]

Published
2024
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14. Pulmonale arterielle Hypertonie bei Erwachsenen mit angeborenen Herzfehlern – Teil I

Author

Kaemmerer, Harald, additional, Diller, Gerhard Paul, additional, Dähnert, Ingo, additional, Eichstaedt, Christina A., additional, Eicken, Andreas, additional, Freiberger, Annika, additional, Freilinger, Sebastian, additional, Geiger, Ralf, additional, Gorenflo, Matthias, additional, Grünig, Ekkehard, additional, Hager, Alfred, additional, Herberg, Ulrike, additional, Huntgeburth, Michael, additional, Kaemmerer, Ann-Sophie, additional, Kozlik-Feldmann, Rainer, additional, Lammers, Astrid, additional, Nagdyman, Nicole, additional, Michel, Sebastian, additional, Schmidt, Kai Helge, additional, Uebing, Anselm, additional, von Scheidt, Fabian, additional, and Apitz, Christian, additional

Published
2023
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16. Somatic Development in Children with Congenital Heart Defects

Author

Kerst, Gunter, Vazquez-Jimenez, Jaime F., Gkalpakiotis, Dimitrios, Schedifka, Andrea, Buheitel, Gernot, Streble, Joachim, II, Kececioglu, Deniz, Sandica, Eugen, Trusen, Burkhard, Berger, Felix, Miera, Oliver, Ovroutski, Stanislav, Peters, Björn, Schmitt, Katharina, Schubert, Stephan, Photiadis, Joachim, Opgen-Rhein, Bernd, Weiss, Katja, Berns, Christoph, Blumenthal-Barby, Carl-Christian, Boeckel, Thomas, Krusche, Susanne, Busse, Jürgen, Kästner, Andreas, Koch, Heike, Köpcke, Christian, Streichan, Frank, Timme, Jens, Franzbach, Birgit, Senft, Gabriela, Beyer, Frank, Winter, Klaus, Breuer, Johannes, Welz, Armin, Bahlmann, Jens, Griese, Eberhard, Lê, Trong Phi, Hebe, Joachim, Nürnberg, Jan-Hendrik, Magsaam, Annette, Müller, Ronald, Potthoff, Ludger, Voigt, Renate, Krüger, Tim, Gerleve, Hubert, Kleideiter, Ulrich, Schneider-Kulla, Dirk, Feil, Elmo, Menke, Thomas, Lehn, Martin, Grohmann, Martina, Tomczak, Helge, Krogmann, Otto N., Tarusinov, Gleb, Scheld, Michael, Mayatepek, Ertan, Pillekamp, Frank, Lichtenberg, Artur, Terpeluk, Christiane, von Jan, Veronika, Dittrich, Sven, Gundlach, Ulrike, Cesnjevar, Robert, Neudorf, Ulrich, Morf, Geert, Esmaeili, Anoosh, Backhoff, Stephan, Stiller, Brigitte, Beyersdorf, Friedhelm, Kroll, Johannes, Wildberg, Anke, Siaplaouras, Jannos, Masri-Zada, Antje, Jux, Christian, Böning, Andreas, Akintürk, Hakan, Paul, Thomas, Tirilomis, Theodor, Schürer, Gabriele, Hartmann, Johannes, Grabitz, Ralph, Liebaug, Uta, Rotzsch, Claudius, Kozlik-Feldmann, Rainer, Sachweh, Jörg, Riso, Arlindo, Petersen, Volker, Friedrich, Bernd, Schlobohm, Otmar, Beerbaum, Philipp, Böthig, Dietmar, Horke, Alexander, Bauersachs, Johann, Westhoff-Bleck, Mechthild, Gorenflo, Matthias, Karck, Matthias, Loukanov, Tsvetomir, Sebening, Christian, Schrüfer, Hermann, Wilken, Martin, Abdul-Khaliq, Hashim, Rädle-Hurst, Tanja, Rentzsch, Axel, Schäfers, Hans-Joachim, Reichert, Hagen, Kriebel, Thomas, Boysen, Arnulf, Kramer, Hans-Heiner, Cremer, Joachim Thomas, Scheewe, Jens, Buchholz-Berdau, Regina, Möller, Peter, Ram, Wolfgang, Brockmeier, Konrad, Bennink, Gerardus B.W.E., Gillor, Alex, Niehues, Tim, Terhoeven, Peter, Leidig, Steffen, Dähnert, Ingo, Kinzel, Peter, Kostelka, Martin, Kändler, Liane, Bethge, Martin, Köster, Stefan, Schröder, Christoph, Karstedt, Jens, Seitz, Uwe, Kampmann, Christoph, Vahl, Christian-Friedrich, Stahl, Frank, Barth, Helmut, Müller-Scholden, Joachim, Ewert, Peter, Hager, Alfred, Kaemmerer, Harald, Nagdyman, Nicole, Schoetzau, Jörg, Tutarel, Oktay, Lange, Rüdiger, Haas, Nikolaus A., Hakami, Lale, Hauser, Michael, Roithmaier, Alexander, Kehl, Hans Gerd, Malec, Edward, Baumgartner, Helmut, Diller, Gerhard, Bahle, Roswitha, Hofner, Gerald, Zink, Stefan, Reif, Roland, Parlasca, Christoph, Freund, Matthias W., Schumacher, Michael, Darrelmann, Christine, Motz, Reinald, Willmann, Olaf, Schmiedl, Norbert, Quick, Peter, Hillebrand, Dirk, Hirsemann, Petra, Eiselt, Stephan Michele, Nekarda, Torsten, Eberhard, Michael, Schneider, Martin, Asfour, Boulos, Baier, Georg, Uhlemann, Frank, Scheid, Michael, Beyer, Alexander, Binz, Gudrun, Teufel, Thomas, Handke, Ronald-Peter, Hofbeck, Michael, Kaulitz, Renate, Sieverding, Ludger, Schlensak, Christian, Apitz, Christian, Kupferschmid, Christoph, Holtvogt, Jürgen, Wippermann, Carl-Friedrich, Heusch, Andreas, Wirbelauer, Johannes, Brosi, Wolfgang, Poryo, Martin, Paes, Laura Antonia, Pickardt, Thomas, Bauer, Ulrike M.M., Meyer, Sascha, and Wagenpfeil, Stefan

Published
2018
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18. Model-driven survival prediction after congenital heart surgery

Author

Zürn, Christoph, primary, Hübner, David, additional, Ziesenitz, Victoria C, additional, Höhn, René, additional, Schuler, Lena, additional, Schlange, Tim, additional, Gorenflo, Matthias, additional, Kari, Fabian A, additional, Kroll, Johannes, additional, Loukanov, Tsvetomir, additional, Klemm, Rolf, additional, and Stiller, Brigitte, additional

Published
2023
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19. Safety and efficacy of mTOR inhibitor treatment in patients with tuberous sclerosis complex under 2 years of age – a multicenter retrospective study

Author

Saffari, Afshin, Brösse, Ines, Wiemer-Kruel, Adelheid, Wilken, Bernd, Kreuzaler, Paula, Hahn, Andreas, Bernhard, Matthias K., van Tilburg, Cornelis M., Hoffmann, Georg F., Gorenflo, Matthias, Hethey, Sven, Kaiser, Olaf, Kölker, Stefan, Wagner, Robert, Witt, Olaf, Merkenschlager, Andreas, Möckel, Andreas, Roser, Timo, Schlump, Jan-Ulrich, Serfling, Antje, Spiegler, Juliane, Milde, Till, Ziegler, Andreas, and Syrbe, Steffen

Published
2019
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27. Riociguat in children with pulmonary arterial hypertension: The PATENT–CHILD study

Author

García Aguilar, Humberto, primary, Gorenflo, Matthias, additional, Ivy, D. Dunbar, additional, Moledina, Shahin, additional, Castaldi, Biagio, additional, Ishida, Hidekazu, additional, Cześniewicz, Paweł, additional, Kusa, Jacek, additional, Miera, Oliver, additional, Pattathu, Joseph, additional, Weng, Ken‐Pen, additional, Ablonczy, Laszlo, additional, Apitz, Christian, additional, Katona, Marta, additional, Kurosaki, Kenichi, additional, Pulido, Tomas, additional, Yamagishi, Hiroyuki, additional, Yasuda, Kazushi, additional, Cisternas, Galia, additional, Goth, Melanie, additional, Lippert, Susanne, additional, Radomskyj, Anna, additional, Saleh, Soundos, additional, Willmann, Stefan, additional, Wirsching, Gabriela, additional, Bonnet, Damien, additional, and Beghetti, Maurice, additional

Published
2022
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30. Efficacy and Safety of NSAIDs in Infants:A Comprehensive Review of the Literature of the Past 20 Years

Author

Ziesenitz, Victoria C., Welzel, Tatjana, van Dyk, Madele, Saur, Patrick, Gorenflo, Matthias, van den Anker, Johannes N., Ziesenitz, Victoria C., Welzel, Tatjana, van Dyk, Madele, Saur, Patrick, Gorenflo, Matthias, and van den Anker, Johannes N.

Abstract

Non-steroidal anti-inflammatory drugs (NSAIDs) are commonly used in infants, children, and adolescents worldwide; however, despite sufficient evidence of the beneficial effects of NSAIDs in children and adolescents, there is a lack of comprehensive data in infants. The present review summarizes the current knowledge on the safety and efficacy of various NSAIDs used in infants for which data are available, and includes ibuprofen, dexibuprofen, ketoprofen, flurbiprofen, naproxen, diclofenac, ketorolac, indomethacin, niflumic acid, meloxicam, celecoxib, parecoxib, rofecoxib, acetylsalicylic acid, and nimesulide. The efficacy of NSAIDs has been documented for a variety of conditions, such as fever and pain. NSAIDs are also the main pillars of anti-inflammatory treatment, such as in pediatric inflammatory rheumatic diseases. Limited data are available on the safety of most NSAIDs in infants. Adverse drug reactions may be renal, gastrointestinal, hematological, or immunologic. Since NSAIDs are among the most frequently used drugs in the pediatric population, safety and efficacy studies can be performed as part of normal clinical routine, even in young infants. Available data sources, such as (electronic) medical records, should be used for safety and efficacy analyses. On a larger scale, existing data sources, e.g. adverse drug reaction programs/networks, spontaneous national reporting systems, and electronic medical records should be assessed with child-specific methods in order to detect safety signals pertinent to certain pediatric age groups or disease entities. To improve the safety of NSAIDs in infants, treatment needs to be initiated with the lowest age-appropriate or weight-based dose. Duration of treatment and amount of drug used should be regularly evaluated and maximum dose limits and other recommendations by the manufacturer or expert committees should be followed. Treatment for non-chronic conditions such as fever and acute (postoperative) pain should be k

Published
2022

31. Somatic Development in Children with Congenital Heart Defects

Author

Poryo, Martin, Paes, Laura Antonia, Pickardt, Thomas, Bauer, Ulrike M.M., Meyer, Sascha, Wagenpfeil, Stefan, Abdul-Khaliq, Hashim, Kerst, Gunter, Vazquez-Jimenez, Jaime F., Gkalpakiotis, Dimitrios, Schedifka, Andrea, Buheitel, Gernot, Streble, Joachim, II, Kececioglu, Deniz, Sandica, Eugen, Trusen, Burkhard, Berger, Felix, Miera, Oliver, Ovroutski, Stanislav, Peters, Björn, Schmitt, Katharina, Schubert, Stephan, Photiadis, Joachim, Opgen-Rhein, Bernd, Weiss, Katja, Berns, Christoph, Blumenthal-Barby, Carl-Christian, Boeckel, Thomas, Krusche, Susanne, Busse, Jürgen, Kästner, Andreas, Koch, Heike, Köpcke, Christian, Streichan, Frank, Timme, Jens, Franzbach, Birgit, Senft, Gabriela, Beyer, Frank, Winter, Klaus, Breuer, Johannes, Welz, Armin, Bahlmann, Jens, Griese, Eberhard, Lê, Trong Phi, Hebe, Joachim, Nürnberg, Jan-Hendrik, Magsaam, Annette, Müller, Ronald, Potthoff, Ludger, Voigt, Renate, Krüger, Tim, Gerleve, Hubert, Kleideiter, Ulrich, Schneider-Kulla, Dirk, Feil, Elmo, Menke, Thomas, Lehn, Martin, Grohmann, Martina, Tomczak, Helge, Krogmann, Otto N., Tarusinov, Gleb, Scheld, Michael, Mayatepek, Ertan, Pillekamp, Frank, Lichtenberg, Artur, Terpeluk, Christiane, von Jan, Veronika, Dittrich, Sven, Gundlach, Ulrike, Cesnjevar, Robert, Neudorf, Ulrich, Morf, Geert, Esmaeili, Anoosh, Backhoff, Stephan, Stiller, Brigitte, Beyersdorf, Friedhelm, Kroll, Johannes, Wildberg, Anke, Siaplaouras, Jannos, Masri-Zada, Antje, Jux, Christian, Böning, Andreas, Akintürk, Hakan, Paul, Thomas, Tirilomis, Theodor, Schürer, Gabriele, Hartmann, Johannes, Grabitz, Ralph, Liebaug, Uta, Rotzsch, Claudius, Kozlik-Feldmann, Rainer, Sachweh, Jörg, Riso, Arlindo, Petersen, Volker, Friedrich, Bernd, Schlobohm, Otmar, Beerbaum, Philipp, Böthig, Dietmar, Horke, Alexander, Bauersachs, Johann, Westhoff-Bleck, Mechthild, Gorenflo, Matthias, Karck, Matthias, Loukanov, Tsvetomir, Sebening, Christian, Schrüfer, Hermann, Wilken, Martin, Abdul-Khaliq, Hashim, Rädle-Hurst, Tanja, Rentzsch, Axel, Schäfers, Hans-Joachim, Reichert, Hagen, Kriebel, Thomas, Boysen, Arnulf, Kramer, Hans-Heiner, Cremer, Joachim Thomas, Scheewe, Jens, Buchholz-Berdau, Regina, Möller, Peter, Ram, Wolfgang, Brockmeier, Konrad, Bennink, Gerardus B.W.E., Gillor, Alex, Niehues, Tim, Terhoeven, Peter, Leidig, Steffen, Dähnert, Ingo, Kinzel, Peter, Kostelka, Martin, Kändler, Liane, Bethge, Martin, Köster, Stefan, Schröder, Christoph, Karstedt, Jens, Seitz, Uwe, Kampmann, Christoph, Vahl, Christian-Friedrich, Stahl, Frank, Barth, Helmut, Müller-Scholden, Joachim, Ewert, Peter, Hager, Alfred, Kaemmerer, Harald, Nagdyman, Nicole, Schoetzau, Jörg, Tutarel, Oktay, Lange, Rüdiger, Haas, Nikolaus A., Hakami, Lale, Hauser, Michael, Roithmaier, Alexander, Kehl, Hans Gerd, Malec, Edward, Baumgartner, Helmut, Diller, Gerhard, Bahle, Roswitha, Hofner, Gerald, Zink, Stefan, Reif, Roland, Parlasca, Christoph, Freund, Matthias W., Schumacher, Michael, Darrelmann, Christine, Motz, Reinald, Willmann, Olaf, Schmiedl, Norbert, Quick, Peter, Hillebrand, Dirk, Hirsemann, Petra, Eiselt, Stephan Michele, Nekarda, Torsten, Eberhard, Michael, Schneider, Martin, Asfour, Boulos, Baier, Georg, Uhlemann, Frank, Scheid, Michael, Beyer, Alexander, Binz, Gudrun, Teufel, Thomas, Handke, Ronald-Peter, Hofbeck, Michael, Kaulitz, Renate, Sieverding, Ludger, Schlensak, Christian, Apitz, Christian, Kupferschmid, Christoph, Holtvogt, Jürgen, Wippermann, Carl-Friedrich, Heusch, Andreas, Wirbelauer, Johannes, and Brosi, Wolfgang

Published
2018
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32. Impact of Right Ventricular Pressure Load After Repair of Tetralogy of Fallot

Author

Latus, Heiner, primary, Stammermann, Jana, additional, Voges, Inga, additional, Waschulzik, Birgit, additional, Gutberlet, Matthias, additional, Diller, Gerhard‐Paul, additional, Schranz, Dietmar, additional, Ewert, Peter, additional, Beerbaum, Philipp, additional, Kühne, Titus, additional, Sarikouch, Samir, additional, Kerst, Gunter, additional, Kanaan, Majed, additional, Lebherz, Corinna, additional, Rüffer, André, additional, Gkalpakiotis, Dimitrios, additional, Schedifka, Andrea, additional, Buheitel, Gernot, additional, Streble, Joachim, additional, Willing, Rainer, additional, Schubert, Stephan, additional, Laser, Kai Thorsten, additional, Sandica, Eugen, additional, Trusen, Burkhard, additional, Berger, Felix, additional, Miera, Oliver, additional, Ovroutski, Stanislav, additional, Schmitt, Katharina, additional, Photiadis, Joachim, additional, Opgen‐Rhein, Bernd, additional, Weiss, Katja, additional, Klaassen, Sabine, additional, Berns, Christoph, additional, Boeckel, Thomas, additional, Haverkämper, Guido, additional, Kästner, Andreas, additional, Koch, Heike, additional, Peters, Björn, additional, Schmidt, Florian, additional, Timme, Jens, additional, Engel, Konstanze, additional, Franzbach, Birgit, additional, Senft, Gabriela, additional, Beyer, Frank, additional, Winter, Klaus, additional, Breuer, Johannes, additional, Schneider, Martin, additional, Bahlmann, Jens, additional, Griese, Eberhard, additional, Lê, Trong Phi, additional, Hebe, Joachim, additional, Nürnberg, Jan‐Hendrik, additional, Magsaam, Annette, additional, Müller, Ronald, additional, Potthoff, Ludger, additional, Voigt, Renate, additional, Krüger, Tim, additional, Gerleve, Hubert, additional, Kleideiter, Ulrich, additional, Schneider‐Kulla, Dirk, additional, Krülls‐Münch, Jürgen, additional, Menke, Thomas, additional, Lehn, Martin, additional, Heilmann, Antje, additional, Tomczak, Helge, additional, Tarusinov, Gleb, additional, Scheid, Michael, additional, Mayatepek, Ertan, additional, Pillekamp, Frank, additional, Lichtenberg, Artur, additional, Terpeluk, Christiane, additional, Kolterer, Bruno, additional, Dittrich, Sven, additional, Gundlach, Ulrike, additional, Cesnjevar, Robert, additional, Müntjes, Carsten, additional, Morf, Geert, additional, Esmaeili, Anoosh, additional, Backhoff, Stephan, additional, Stiller, Brigitte, additional, Beyersdorf, Friedhelm, additional, Kroll, Johannes, additional, Häffner, Nicole, additional, Siaplaouras, Jannos, additional, Masri‐Zada, Antje, additional, Jux, Christian, additional, Böning, Andreas, additional, Akintürk, Hakan, additional, Paul, Thomas, additional, Sigler, Matthias, additional, Tirilomis, Theodor, additional, Schürer, Gabriele, additional, Hartmann, Johannes, additional, Grabitz, Ralph, additional, Liebaug, Uta, additional, Rotzsch, Claudius, additional, Kozlik‐Feldmann, Rainer, additional, Rickers, Carsten, additional, Mir, Thomas, additional, Hübler, Michael, additional, Sachweh, Jörg, additional, Renz, Stefan, additional, Schemm, Andreas, additional, Friedrich, Bernd, additional, Schlobohm, Otmar, additional, Böthig, Dietmar, additional, Wermter, Burkhard, additional, Kelter‐Klöpping, Andrea, additional, Horke, Alexander, additional, Bauersachs, Johann, additional, Westhoff‐Bleck, Mechthild, additional, Gorenflo, Matthias, additional, Karck, Matthias, additional, Loukanov, Tsvetomir, additional, Schrüfer, Hermann, additional, Wilken, Martin, additional, Abdul‐Khaliq, Hashim, additional, Rädle‐Hurst, Tanja, additional, Rentzsch, Axel, additional, Schäfers, Hans‐Joachim, additional, Reichert, Hagen, additional, Vilser, Daniel, additional, Kriebel, Thomas, additional, Boysen, Arnulf, additional, Uebing, Anselm, additional, Attmann, Tim, additional, Cremer, Joachim Thomas, additional, Scheewe, Jens, additional, Buchholz‐Berdau, Regina, additional, Möller, Peter, additional, Horter, Thorsten, additional, Brockmeier, Konrad, additional, Bennink, Gerardus B. W. E, additional, Baldus, Stephan, additional, Gillor, Alex, additional, Niehues, Tim, additional, Lawrenz, Wolfgang, additional, Leidig, Steffen, additional, Dähnert, Ingo, additional, Riede, Frank‐Thomas, additional, Kostelka, Martin, additional, Kändler, Liane, additional, Bethge, Martin, additional, Köster, Stefan, additional, Schröder, Christoph, additional, Karstedt, Jens, additional, Seitz, Uwe, additional, Kampmann, Christoph, additional, Dohle, Daniel‐Sebastian, additional, Stahl, Frank, additional, Abedini, Mojtaba, additional, Müller‐Scholden, Joachim, additional, Hager, Alfred, additional, Huntgeburth, Michael, additional, Kaemmerer, Harald, additional, Nagdyman, Nicole, additional, Schoetzau, Jörg, additional, Tutarel, Oktay, additional, Lange, Rüdiger, additional, Hörer, Jürgen, additional, Haas, Nikolaus A, additional, Hauser, Michael, additional, Roithmaier, Alexander, additional, Kehl, Hans‐Gerd, additional, Lammers, Astrid, additional, Malec, Edward, additional, Baumgartner, Helmut, additional, Diller, Gerhard, additional, Bahle, Roswitha, additional, Hofner, Gerald, additional, Zink, Stefan, additional, Reif, Roland, additional, Singer, Helmut, additional, Parlasca, Christoph, additional, Freund, Matthias W, additional, Schumacher, Michael, additional, Dewald, Oliver, additional, Darrelmann, Christine, additional, Willmann, Olaf, additional, Schmiedl, Norbert, additional, Quick, Peter, additional, Hillebrand, Dirk, additional, Michele Eiselt, Stephan, additional, Nekarda, Torsten, additional, Eberhard, Michael, additional, Baier, Georg, additional, Uhlemann, Frank, additional, Tzanavaros, Ioannis, additional, Beyer, Alexander, additional, Binz, Gudrun, additional, Hess, Steffen, additional, Teufel, Thomas, additional, Handke, Ronald‐Peter, additional, Hofbeck, Michael, additional, Kaulitz, Renate, additional, Sieverding, Ludger, additional, Schlensak, Christian, additional, Apitz, Christian, additional, Kaestner, Michael, additional, Holtvogt, Jürgen, additional, Wippermann, Carl‐Friedrich, additional, Hinz, Sönke, additional, Heusch, Andreas, additional, Wirbelauer, Johannes, additional, and Brosi, Wolfgang, additional

Published
2022
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34. Medical treatment of pulmonary hypertension in adults with congenital heart disease: updated and extended results from the International COMPERA-CHD Registry

Author

Kaemmerer, Ann-Sophie, primary, Gorenflo, Matthias, additional, Huscher, Dörte, additional, Pittrow, David, additional, Ewert, Peter, additional, Pausch, Christine, additional, Delcroix, Marion, additional, Ghofrani, Hossein A., additional, Hoeper, Marius M., additional, Kozlik-Feldmann, Rainer, additional, Skride, Andris, additional, Stähler, Gerd, additional, Vizza, Carmine Dario, additional, Jureviciene, Elena, additional, Jancauskaite, Dovile, additional, Gumbiene, Lina, additional, Ewert, Ralf, additional, Dähnert, Ingo, additional, Held, Matthias, additional, Halank, Michael, additional, Skowasch, Dirk, additional, Klose, Hans, additional, Wilkens, Heinrike, additional, Milger, Katrin, additional, Jux, Christian, additional, Koestenberger, Martin, additional, Scelsi, Laura, additional, Brunnemer, Eva, additional, Hofbeck, Michael, additional, Ulrich, Silvia, additional, Noordegraaf, Anton Vonk, additional, Lange, Tobias J., additional, Bruch, Leonhard, additional, Konstantinides, Stavros, additional, Claussen, Martin, additional, Löffler-Ragg, Judith, additional, Wirtz, Hubert, additional, Apitz, Christian, additional, Neidenbach, Rhoia, additional, Freilinger, Sebastian, additional, Nemes, Attila, additional, Opitz, Christian, additional, Grünig, Ekkehard, additional, and Rosenkranz, Stephan, additional

Published
2021
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35. 2015 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension: The Joint Task Force for the Diagnosis and Treatment of Pulmonary Hypertension of the European Society of Cardiology (ESC) and the European Respiratory Society (ERS): Endorsed by: Association for European Paediatric and Congenital Cardiology (AEPC), International Society for Heart and Lung Transplantation (ISHLT)

Author

Galiè, Nazzareno, Humbert, Marc, Vachiery, Jean-Luc, Gibbs, Simon, Lang, Irene, Torbicki, Adam, Simonneau, Gérald, Peacock, Andrew, Vonk Noordegraaf, Anton, Beghetti, Maurice, Ghofrani, Ardeschir, Gomez Sanchez, Miguel Angel, Hansmann, Georg, Klepetko, Walter, Lancellotti, Patrizio, Matucci, Marco, McDonagh, Theresa, Pierard, Luc A., Trindade, Pedro T., Zompatori, Maurizio, Hoeper, Marius, Aboyans, Victor, Vaz Carneiro, Antonio, Achenbach, Stephan, Agewall, Stefan, Allanore, Yannick, Asteggiano, Riccardo, Paolo Badano, Luigi, Albert Barberà, Joan, Bouvaist, Hélène, Bueno, Héctor, Byrne, Robert A., Carerj, Scipione, Castro, Graça, Erol, Çetin, Falk, Volkmar, Funck-Brentano, Christian, Gorenflo, Matthias, Granton, John, Iung, Bernard, Kiely, David G., Kirchhof, Paulus, Kjellstrom, Barbro, Landmesser, Ulf, Lekakis, John, Lionis, Christos, Lip, Gregory Y. H., Orfanos, Stylianos E., Park, Myung H., Piepoli, Massimo F., Ponikowski, Piotr, Revel, Marie-Pierre, Rigau, David, Rosenkranz, Stephan, Völler, Heinz, and Luis Zamorano, Jose

Published
2016
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38. Fetal Cardiac Services during the COVID-19 Pandemic: How Does It Affect Parental Counseling?

Author

Kovacevic, Alexander, primary, Bär, Stefan, additional, Starystach, Sebastian, additional, Elsässer, Michael, additional, van der Locht, Thomas, additional, Mohammadi Motlagh, Aida, additional, Ostermayer, Eva, additional, Oberhoffer-Fritz, Renate, additional, Ewert, Peter, additional, Gorenflo, Matthias, additional, and Wacker-Gussmann, Annette, additional

Published
2021
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39. Medical treatment of pulmonary hypertension in adults with congenital heart disease: updated and extended results from the International COMPERA-CHD Registry

Author

Kaemmerer, Ann-Sophie, Gorenflo, Matthias, Huscher, Doerte, Pittrow, David, Ewert, Peter, Pausch, Christine, Delcroix, Marion, Ghofrani, Hossein A., Hoeper, Marius M., Kozlik-Feldmann, Rainer, Skride, Andris, Staehler, Gerd, Vizza, Carmine Dario, Jureviciene, Elena, Jancauskaite, Dovile, Gumbiene, Lina, Ewert, Ralf, Daehnert, Ingo, Held, Matthias, Halank, Michael, Skowasch, Dirk, Klose, Hans, Wilkens, Heinrike, Milger, Katrin, Jux, Christian, Koestenberger, Martin, Scelsi, Laura, Brunnemer, Eva, Hofbeck, Michael, Ulrich, Silvia, Noordegraaf, Anton Vonk, Lange, Tobias J., Bruch, Leonhard, Konstantinides, Stavros, Claussen, Martin, Loeffler-Ragg, Judith, Wirtz, Hubert, Apitz, Christian, Neidenbach, Rhoia, Freilinger, Sebastian, Nemes, Attila, Opitz, Christian, Gruenig, Ekkehard, Rosenkranz, Stephan, Kaemmerer, Ann-Sophie, Gorenflo, Matthias, Huscher, Doerte, Pittrow, David, Ewert, Peter, Pausch, Christine, Delcroix, Marion, Ghofrani, Hossein A., Hoeper, Marius M., Kozlik-Feldmann, Rainer, Skride, Andris, Staehler, Gerd, Vizza, Carmine Dario, Jureviciene, Elena, Jancauskaite, Dovile, Gumbiene, Lina, Ewert, Ralf, Daehnert, Ingo, Held, Matthias, Halank, Michael, Skowasch, Dirk, Klose, Hans, Wilkens, Heinrike, Milger, Katrin, Jux, Christian, Koestenberger, Martin, Scelsi, Laura, Brunnemer, Eva, Hofbeck, Michael, Ulrich, Silvia, Noordegraaf, Anton Vonk, Lange, Tobias J., Bruch, Leonhard, Konstantinides, Stavros, Claussen, Martin, Loeffler-Ragg, Judith, Wirtz, Hubert, Apitz, Christian, Neidenbach, Rhoia, Freilinger, Sebastian, Nemes, Attila, Opitz, Christian, Gruenig, Ekkehard, and Rosenkranz, Stephan

Abstract

Background: Pulmonary arterial hypertension (PAH) is common in congenital heart disease (CHD). Because clinical-trial data on PAH associated with CHD (PAH-CHD) remain limited, registry data on the long-term course are essential. This analysis aimed to update information from the COMPERA-CHD registry on management strategies based on real-world data. Methods: The prospective international pulmonary hypertension registry COMPERA has since 2007 enrolled more than 10,000 patients. COMPERA-CHD is a sub-registry for patients with PAH-CHD Results: A total of 769 patients with PAH-CHD from 62 specialized centers in 12 countries were included into COMPERA-CHD from January 2007 through September 2020. At the last follow-up in 09/2020, patients [mean age 45.3 +/- 16.8 years; 512 (66%) female] had either post-tricuspid shunts (n=359; 46.7%), pre-tricuspid shunts (n=249; 32.4%), complex CHD (n=132; 17.2%), congenital left heart or aortic valve or aortic disease (n=9; 1.3%), or miscellaneous CHD (n=20; 2.6%). The mean 6-minute walking distance was 369 +/- 121 m, and 28.2%, 56.0%, and 3.8% were in WHO functional class I/II, III or IV, respectively (12.0% unknown). Compared with the previously published COMPERA-CHD data, after 21 months of followup, the number of included PAH-CHD patients increased by 91 (13.4%). Within this group the number of Eisenmenger patients rose by 39 (16.3%), the number of Non-Eisenmenger PAH patients by 45 (26.9%). Currently, among the 674 patients from the PAH-CHD group with at least one follow-up, 450 (66.8%) received endothelin receptor antagonists (ERA), 416 (61.7%) PDE-5 inhibitors, 85 (12.6%) prostacyclin analogues, and 36 (5.3%) the sGC stimulator riociguat. While at first inclusion in the COMPERA-CHD registry, treatment was predominantly monotherapy (69.3%), this has shifted to favoring combination therapy in the current group (53%). For the first time, the nature, frequency, and treatment of significant comorbidities requiring supportive care and

Published
2021

40. Parents’ Perspectives on Counseling for Fetal Heart Disease: What Matters Most?

Author

Kovacevic, Alexander;Wacker-Gussmann, Annette;Bär, Stefan;Elsässer, Michael;Mohammadi Motlagh, Aida;Ostermayer, Eva;Oberhoffer-Fritz, Renate;Ewert, Peter;Gorenflo, Matthias;Starystach, Sebastian and Kovacevic, Alexander;Wacker-Gussmann, Annette;Bär, Stefan;Elsässer, Michael;Mohammadi Motlagh, Aida;Ostermayer, Eva;Oberhoffer-Fritz, Renate;Ewert, Peter;Gorenflo, Matthias;Starystach, Sebastian

Published
2021

42. Fetal Cardiac Services during the COVID-19 Pandemic: How Does It Affect Parental Counseling?

Author

Kovacevic, Alexander;Bär, Stefan;Starystach, Sebastian;Elsässer, Michael;van der Locht, Thomas;Mohammadi Motlagh, Aida;Ostermayer, Eva;Oberhoffer-Fritz, Renate;Ewert, Peter;Gorenflo, Matthias;Wacker-Gussmann, Annette and Kovacevic, Alexander;Bär, Stefan;Starystach, Sebastian;Elsässer, Michael;van der Locht, Thomas;Mohammadi Motlagh, Aida;Ostermayer, Eva;Oberhoffer-Fritz, Renate;Ewert, Peter;Gorenflo, Matthias;Wacker-Gussmann, Annette

Published
2020

43. Chromatin accessibility landscape of pediatric T-lymphoblastic leukemia and human T-cell precursors

Author

Erarslan-Uysal, Büşra; https://orcid.org/0000-0002-7135-2201, Kunz, Joachim B, Rausch, Tobias; https://orcid.org/0000-0001-5773-5620, Richter-Pechańska, Paulina, van Belzen, Ianthe Aem, Frismantas, Viktoras, Bornhauser, Beat, Ordoñez-Rueada, Diana, Paulsen, Malte, Benes, Vladimir, Stanulla, Martin, Schrappe, Martin, Cario, Gunnar, Escherich, Gabriele, Bakharevich, Kseniya, Kirschner-Schwabe, Renate, Eckert, Cornelia, Loukanov, Tsvetomir, Gorenflo, Matthias, Waszak, Sebastian M, Bourquin, Jean-Pierre, Muckenthaler, Martina U, Korbel, Jan O; https://orcid.org/0000-0002-2798-3794, Kulozik, Andreas E; https://orcid.org/0000-0003-1953-0848, Erarslan-Uysal, Büşra; https://orcid.org/0000-0002-7135-2201, Kunz, Joachim B, Rausch, Tobias; https://orcid.org/0000-0001-5773-5620, Richter-Pechańska, Paulina, van Belzen, Ianthe Aem, Frismantas, Viktoras, Bornhauser, Beat, Ordoñez-Rueada, Diana, Paulsen, Malte, Benes, Vladimir, Stanulla, Martin, Schrappe, Martin, Cario, Gunnar, Escherich, Gabriele, Bakharevich, Kseniya, Kirschner-Schwabe, Renate, Eckert, Cornelia, Loukanov, Tsvetomir, Gorenflo, Matthias, Waszak, Sebastian M, Bourquin, Jean-Pierre, Muckenthaler, Martina U, Korbel, Jan O; https://orcid.org/0000-0002-2798-3794, and Kulozik, Andreas E; https://orcid.org/0000-0003-1953-0848

Abstract

We aimed at identifying the developmental stage at which leukemic cells of pediatric T-ALLs are arrested and at defining leukemogenic mechanisms based on ATAC-Seq. Chromatin accessibility maps of seven developmental stages of human healthy T cells revealed progressive chromatin condensation during T-cell maturation. Developmental stages were distinguished by 2,823 signature chromatin regions with 95% accuracy. Open chromatin surrounding SAE1 was identified to best distinguish thymic developmental stages suggesting a potential role of SUMOylation in T-cell development. Deconvolution using signature regions revealed that T-ALLs, including those with mature immunophenotypes, resemble the most immature populations, which was confirmed by TF-binding motif profiles. We integrated ATAC-Seq and RNA-Seq and found DAB1, a gene not related to leukemia previously, to be overexpressed, abnormally spliced and hyper-accessible in T-ALLs. DAB1-negative patients formed a distinct subgroup with particularly immature chromatin profiles and hyper-accessible binding sites for SPI1 (PU.1), a TF crucial for normal T-cell maturation. In conclusion, our analyses of chromatin accessibility and TF-binding motifs showed that pediatric T-ALL cells are most similar to immature thymic precursors, indicating an early developmental arrest.

Published
2020

44. Acute Cardiovascular Manifestations in 286 Children With Multisystem Inflammatory Syndrome Associated With COVID-19 Infection in Europe

Author

Valverde, Israel, primary, Singh, Yogen, additional, Sanchez-de-Toledo, Joan, additional, Theocharis, Paraskevi, additional, Chikermane, Ashish, additional, Di Filippo, Sylvie, additional, Kuciñska, Beata, additional, Mannarino, Savina, additional, Tamariz-Martel, Amalia, additional, Gutierrez-Larraya, Federico, additional, Soda, Giridhar, additional, Vandekerckhove, Kristof, additional, Gonzalez-Barlatay, Francisco, additional, McMahon, Colin Joseph, additional, Marcora, Simona, additional, Napoleone, Carlo Pace, additional, Duong, Phuoc, additional, Tuo, Giulia, additional, Deri, Antigoni, additional, Nepali, Gauri, additional, Ilina, Maria, additional, Ciliberti, Paolo, additional, Miller, Owen, additional, Iriart, Xavier, additional, Hubrechts, Jelena, additional, Kuipers, Irene Mariette, additional, Sousa, Ana R., additional, Donti, Andrea, additional, Sharpe, Abigail, additional, Reinhardt, Zdenka, additional, Cairello, Francesca, additional, De Wolf, Daniel, additional, Vieira, Marisa, additional, Lazea, Cecilia, additional, Gran, Ferran, additional, Medrano-Lopez, Constancio, additional, Ortiz-Garrido, Almudena, additional, Vukomanovic, Vladislav, additional, Brent, Bernadette Elisabeth, additional, Milanesi, Ornella, additional, Dewals, Wendy, additional, Manso, Begoña, additional, Valsangiacomo-Buchel, Emanuela, additional, Francisco, Andreia, additional, Seghaye, Marie-Christine, additional, Loeckx, Isabelle, additional, Rodriguez-Gonzalez, Moises, additional, ReyGarcía, Susana Maria, additional, Ziesenitz, Victoria C, additional, Bordin, Giulia, additional, Doros, Gabriela, additional, Grangl, Gernot, additional, Fadl, Shalan Uaid, additional, Perminow, Karl Viktor, additional, Centeno, Fernando, additional, Pinto, Fatima, additional, Niemelä, Jussi, additional, Kanthimathinathan, Hari Krishnan, additional, Randanne, Paula Cecilia, additional, Niszczota, Cezary, additional, Zuccotti, Gian Vincenzo, additional, Gordillo, Inés Leoz, additional, Obeyasekhara, Madhu, additional, Armstrong, Catherine, additional, Butler, Karina, additional, Ciuffreda, Matteo, additional, Villar, Anna Maria, additional, Pappula, Naga, additional, Caorsi, Roberta, additional, Singh, Davinder, additional, Durairaj, Saravanan, additional, McLeod, Karen, additional, Calcagni, Giulio, additional, Quizad, Youssef, additional, Gewillig, Marc, additional, Kuijpers, Taco Willem, additional, Ataide, Rita, additional, Fabi, Marianna, additional, Bharucha, Tara, additional, Abbas, Khushnood, additional, Magrass, Silvia Alessandra, additional, Wong, James, additional, Iacob, Daniela, additional, Balcells, Joan, additional, GilVillanueva, Nuria, additional, Cuenca-Peiro, Victorio, additional, Cerovi, Ivana, additional, Sarfatt, Avishay, additional, Zaqout, Mahmoud, additional, Sanchez-Valderrabanos, Elia, additional, Kelly-Geyer, Janet, additional, Diogo, Faim, additional, Cajgfinger, Nathalie, additional, Françoise, Mascart, additional, Rueda-Nuñez, Fernando, additional, Gorenflo, Matthias, additional, Grison, Alessandra, additional, Mihailov, Delia, additional, Koestenberger, Martin, additional, Alcalde, Carlos, additional, Trigo, Conceiçao, additional, Arola, Anita, additional, and Hanseus, Katarina, additional

Published
2021
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45. Response to: ‘ Correspondence on ‘Haemodynamic phenotypes and survival in patients with systemic sclerosis: the impact of the new definition of pulmonary arterial hypertension’’ by Iudici et al

Author

Grünig, Ekkehard, primary, Benjamin, Nicola, additional, Xanthouli, Panagiota, additional, Jordan, Suzana, additional, Milde, Nicklas, additional, Marra, Alberto, additional, Blank, Norbert, additional, Egenlauf, Benjamin, additional, Gorenflo, Matthias, additional, Harutyunova, Satenik, additional, Lorenz, Hanns-Martin, additional, Nagel, Christian, additional, Theobald, Vivienne, additional, Lichtblau, Mona, additional, Berlier, Charlotte, additional, Ulrich, Silvia, additional, and Distler, Oliver, additional

Published
2020
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47. Chromatin accessibility landscape of pediatric T‐lymphoblastic leukemia and human T‐cell precursors

Author

Erarslan‐Uysal, Büşra, primary, Kunz, Joachim B, additional, Rausch, Tobias, additional, Richter‐Pechańska, Paulina, additional, Belzen, Ianthe AEM, additional, Frismantas, Viktoras, additional, Bornhauser, Beat, additional, Ordoñez‐Rueada, Diana, additional, Paulsen, Malte, additional, Benes, Vladimir, additional, Stanulla, Martin, additional, Schrappe, Martin, additional, Cario, Gunnar, additional, Escherich, Gabriele, additional, Bakharevich, Kseniya, additional, Kirschner‐Schwabe, Renate, additional, Eckert, Cornelia, additional, Loukanov, Tsvetomir, additional, Gorenflo, Matthias, additional, Waszak, Sebastian M, additional, Bourquin, Jean‐Pierre, additional, Muckenthaler, Martina U, additional, Korbel, Jan O, additional, and Kulozik, Andreas E, additional

Published
2020
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48. Pulmonary Hypertension in Adults with Congenital Heart Disease: Real-World Data from the International COMPERA-CHD Registry

Author

Kaemmerer, Harald, primary, Gorenflo, Matthias, additional, Huscher, Dörte, additional, Pittrow, David, additional, Apitz, Christian, additional, Baumgartner, Helmut, additional, Berger, Felix, additional, Bruch, Leonhard, additional, Brunnemer, Eva, additional, Budts, Werner, additional, Claussen, Martin, additional, Coghlan, Gerry, additional, Dähnert, Ingo, additional, D’Alto, Michele, additional, Delcroix, Marion, additional, Distler, Oliver, additional, Dittrich, Sven, additional, Dumitrescu, Daniel, additional, Ewert, Ralf, additional, Faehling, Martin, additional, Germund, Ingo, additional, Ghofrani, Hossein Ardeschir, additional, Grohé, Christian, additional, Grossekreymborg, Karsten, additional, Halank, Michael, additional, Hansmann, Georg, additional, Harzheim, Dominik, additional, Nemes, Attila, additional, Havasi, Kalman, additional, Held, Matthias, additional, M. Hoeper, Marius, additional, Hofbeck, Michael, additional, Hohenfrost-Schmidt, Wolfgang, additional, Jurevičienė, Elena, additional, Gumbienè, Lina, additional, Kabitz, Hans-Joachim, additional, Klose, Hans, additional, Köhler, Thomas, additional, Konstantinides, Stavros, additional, Köestenberger, Martin, additional, Kozlik-Feldmann, Rainer, additional, Kramer, Hans-Heiner, additional, Kropf-Sanchen, Cornelia, additional, Lammers, Astrid, additional, Lange, Tobias, additional, Meyn, Philipp, additional, Miera, Oliver, additional, Milger-Kneidinger, Katrin, additional, Neidenbach, Rhoia, additional, Neurohr, Claus, additional, Opitz, Christian, additional, Perings, Christian, additional, Remppis, Bjoern Andrew, additional, Riemekasten, Gabriele, additional, Scelsi, Laura, additional, Scholtz, Werner, additional, Simkova, Iveta, additional, Skowasch, Dirk, additional, Skride, Andris, additional, Stähler, Gerd, additional, Stiller, Brigitte, additional, Tsangaris, Iraklis, additional, Vizza, Carmine Dario, additional, Vonk Noordegraaf, Anton, additional, Wilkens, Heinrike, additional, Wirtz, Hubert, additional, Diller, Gerhard-Paul, additional, Grünig, Ekkehard, additional, and Rosenkranz, Stephan, additional

Published
2020
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50. Objective Assessment of Counselling for Fetal Heart Defects: An Interdisciplinary Multicenter Study

Author

Kovacevic, Alexander, primary, Bär, Stefan, additional, Starystach, Sebastian, additional, Simmelbauer, Andreas, additional, Elsässer, Michael, additional, Müller, Andreas, additional, Mohammadi Motlagh, Aida, additional, Oberhoffer-Fritz, Renate, additional, Ostermayer, Eva, additional, Ewert, Peter, additional, Gorenflo, Matthias, additional, and Wacker-Gussmann, Annette, additional

Published
2020
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