Author: "Giani A" / Publication Year Range: Last 10 years - Searchworks@Jio Institute Digital Library Search Results

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1. Toward a Comprehensive Model Predicting Credit Loss in Vertical Transfer. EdWorkingPaper No. 24-1050

Author: Annenberg Institute for School Reform at Brown University, Matt S. Giani, Lauren Schudde, and Tasneem Sultana
Abstract: A growing body of research has documented extensive credit loss among transfer students. However, the field lacks theoretically driven and empirically supported frameworks that can guide credit loss research and reforms. We develop and then test a comprehensive framework designed to address this gap using novel administrative credit loss data from Texas. Our results demonstrate how the likelihood of credit loss varies across course characteristics, majors, pretransfer academics, student characteristics, and sending and receiving institutions. Additionally, we are able to disentangle general credit loss from major credit loss and examine how they vary across institutions, majors, and the combination of both. The extensive variation in credit loss among universities in particular underscores the need for future research and reform.
Published: 2024

2. Credit Loss, Institutional Retention, and Postsecondary Persistence among Vertical Transfer Students. EdWorkingPaper No. 24-1051

Author: Annenberg Institute for School Reform at Brown University, Matt S. Giani, Lauren Schudde, and Tasneem Sultana
Abstract: Although community colleges have served as a gateway to universities for millions of students--disproportionately so for students from populations historically underrepresented in higher education--prior research has demonstrated that the majority of vertical transfer students lose at least some of their pretransfer credits. However, researchers examining how credit loss relates to subsequent college outcomes have been hindered by data limitations. For this study, we drew from the literature on academic momentum and examined the relationship between credit loss, institutional retention, and postsecondary persistence. Our use of novel administrative data from Texas enabled us to disentangle major credit loss from general credit loss and study the contribution of each credit loss type to posttransfer outcomes. Our analyses show that both forms of credit loss are inversely related to institutional retention, but the relationships between credit loss and postsecondary persistence are far less consistent. We found evidence suggesting that major credit loss is more strongly related to both retention and persistence than general credit loss. We did not find evidence that the relationship between credit loss and posttransfer outcomes is moderated by students' race/ethnicity, economic status, or gender, and we found only limited evidence of moderation by major.
Published: 2024

3. Senescent adipocytes as potential effectors of muscle cells dysfunction: An in vitro model

Author: Zoico Elena, Saatchi Tanaz, Nori Nicole, Mazzali Gloria, Rizzatti Vanni, Pizzi Eleonora, Fantin Francesco, Giani Anna, Urbani Silvia, and Zamboni Mauro
Subjects: Aging, Adipose tissue, Skeletal muscle, Senescence, Myostatin, Medicine, Biology (General), QH301-705.5
Abstract: Recently, there has been a growing body of evidence showing a negative effect of the white adipose tissue (WAT) dysfunction on the skeletal muscle function and quality. However, little is known about the effects of senescent adipocytes on muscle cells.Therefore, to explore potential mechanisms involved in age-related loss of muscle mass and function, we performed an in vitro experiment using conditioned medium obtained from cultures of mature and aged 3 T3-L1 adipocytes, as well as from cultures of dysfunctional adipocytes exposed to oxidative stress or high insulin doses, to treat C2C12 myocytes.The results from morphological measures indicated a significant decrease in diameter and fusion index of myotubes after treatment with medium of aged or stressed adipocytes. Aged and stressed adipocytes presented different morphological characteristics as well as a different gene expression profile of proinflammatory cytokines and ROS production. In myocytes treated with different adipocytes' conditioned media, we demonstrated a significant reduction of gene expression of myogenic differentiation markers as well as a significant increase of genes involved in atrophy. Finally, a significant reduction in protein synthesis as well as a significant increase of myostatin was found in muscle cells treated with medium of aged or stressed adipocytes compared to controls.In conclusion, these preliminary results suggest that aged adipocytes could influence negatively trophism, function and regenerative capacity of myocytes by a paracrine network of signaling.
Published: 2023
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4. The Dynamics of Wayang Golek in Pandemic and Globalization: Traditional Art Sustainability

Author: Mohammad Rindu Fajar Islamy, Aam Abdussalam, and Giani Adzkia
Subjects: cultural arts, traditional, wayang golek, covid-19 pandemic, problems, Geography. Anthropology. Recreation, Anthropology, GN1-890, Ethnology. Social and cultural anthropology, GN301-674, Islam, BP1-253
Abstract: This research aims to explore the dynamics of wayang golek art and to highlight its sustainability in the future. Modernity, the acceleration of technological devices and globalization wave in the last two decades, transfers great pressure on traditional arts and culture. Wayang Golek, a performing art originally from West Java, has recently received a fairly strong wave of resistance due to changes in the social culture which is mainly leading to modernity. By using a qualitative approach, data collection techniques were carried out by interviewing two main players as the puppeteers of Wayang Golek. The data analysis uses the theory of Miles and Hubberman, and the theoretical review of Islamic studies. The results of the study show that 1) Wayang Golek has unique characteristics, where the talent needed tends to go through the "inheritance" tradition, 2) Wayang Golek can be a bridge for internalizing religious and humanist values for the community through unique stories based on custom, 3) the restriction of Wayang Golek performance due to the Covid-19 pandemic leads the puppeteers to be more creative to survive, such as creating videos and uploading them in YouTube and other social media, and 4) the preservation of this art depends on the serious attention of all parties, from the government, regional officials, and the community. Penelitian ini bertujuan untuk mengeskplorasi dinamika kesenian wayang golek, serta menyoroti keberlangsungan ‘hidup’ seni tradisional wayang golek dimasa yang akan datang. Era modernitas, akselerasi perangkat teknologi dan gelombang arus globalisasi dalam dua dekade terakhir, memberikan tekanan hebat pada wilayah seni dan budaya tradisional. Wayang Golek sebuah seni pertunjukkan yang berasal dari Jawa Barat akhir-akhir ini mengalami gelombang resistensi cukup kuat imbas dari perubahan kultur sosial masyarakat yang bergerak kearah modernitas. Dengan menggunakan pendekatan kualitatif, teknik pengumpulan data dilakukan dengan wawancara terhadap dua pemain utama sebagai “Dalang” Wayang Golek, observasi dan dokumentasi. Adapun analisis data menggunakan teori Miles dan Hubberman, dan kajian teoritis Islamic studies. Hasil penelitian menunjukkan bahwa 1) Seni Wayang Golek memiliki karakteristik unik, dimana bakat yang dibutuhkan cenderung melalui tradisi “warisan”, 2) Wayang Golek dapat menjadi jembatan internalisasi nilai-nilai religius dan humanis bagi masyarakat melalui cerita-cerita unik berbasis adat, 3) dilarangnya pagelaran Wayang Golek akibat pandemi Covid-19 membuat para dalang lebih kreatif untuk bertahan, seperti membuat video dan menunggahnya ke YouTube dan media sosial yang lain, dan 4) Kelestarian kesenian ini bergantung terhadap perhatian serius semua pihak baik dari pemerintah, pejabat daerah, maupun masyarakat.
Published: 2021
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5. THE ROLE OF THE YOUNGER GENERATION IN PREVENTING THE SPREAD OF RELIGIOUS RADICALISM

Author: Giani Adzkia and Hasuenah Wohseng
Subjects: islam, radicalism, religion, young generation, Islam, BP1-253, Philosophy. Psychology. Religion
Abstract: The spread of radicalism never stops in the span of the history of Muslims from the past until now. Although radicalismis often associatedwith Islam, thereis no fact that Islam is a religion that teaches peace, there has never been an element of religious coercion against others and does not condone the practice of using violence in spreading religious understanding. Meanwhile, radicalism is an understanding that seeks to impose religious opinions, desires, and ideals to realize certain goals through the path of violence. The spread of radicalism can be a real threat to all circles, including the younger generation. The younger generation is more likely to be involved in radical groups, in addition the younger generation is often the main target in the spread of radical understanding because so far the younger generation is very easy to influence. But actually the younger generation has a very important role in preventing the spread of radicalism, considering the younger generation is the next generation of the nation that will challenge the future of the nation. Therefore, the role of the younger generation becomes very important in maintaining unity, unity and preventing the spread of radicalism.
Published: 2021
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6. Origin and Limits of Invariant Warming Patterns in Climate Models

Author: Giani, Paolo, Fiore, Arlene M., Flierl, Glenn, Ferrari, Raffaele, and Selin, Noelle E.
Subjects: Physics - Atmospheric and Oceanic Physics
Abstract: Climate models exhibit an approximately invariant surface warming pattern in typical end-of-century projections. This observation has been used extensively in climate impact assessments for fast calculations of local temperature anomalies, with a linear procedure known as pattern scaling. At the same time, emerging research has also shown that time-varying warming patterns are necessary to explain the time evolution of effective climate sensitivity in coupled models, a mechanism that is known as the pattern effect and that seemingly challenges the pattern scaling understanding. Here we present a simple theory based on local energy balance arguments to reconcile this apparent contradiction. Specifically, we show that the pattern invariance is an inherent feature of exponential forcing, linear feedbacks, a constant forcing pattern and diffusive dynamics. These conditions are approximately met in most CMIP6 Shared Socioeconomic Pathways (SSP), except in the Arctic where nonlinear feedbacks are important and in regions where aerosols considerably alter the forcing pattern. In idealized experiments where concentrations of CO2 are abruptly increased, such as those used to study the pattern effect, the warming pattern can change considerably over time because of spatially inhomogeneous ocean heat uptake, even in the absence of nonlinear feedbacks. Our results illustrate why typical future projections are amenable to pattern scaling, and provide a plausible explanation of why more complicated approaches, such as nonlinear emulators, have only shown marginal improvements in accuracy over simple linear calculations., Comment: To be submitted to J Clim
Published: 2024

7. A novel approach to cosmological non-linearities as an effective fluid

Author: Giani, Leonardo, Von Marttens, Rodrigo, and Camilleri, Ryan
Subjects: Astrophysics - Cosmology and Nongalactic Astrophysics, General Relativity and Quantum Cosmology
Abstract: We propose a two parameters extension of the flat $\Lambda$CDM model to capture the impact of matter inhomogeneities on the background evolution of the Universe. Non virialized but non-linearly evolving overdense and underdense regions, whose abundance is quantified using the Press-Schechter formalism, are collectively described by two effective perfect fluids $\rho_{\rm{c}},\rho_{\rm{v}}$ with non vanishing equation of state parameters $w_{\rm{c,v}}\neq 0$. These fluids are coupled to the pressureless dust, akin to an interacting DM-DE scenario. The resulting phenomenology is very rich, and could potentially address a number of inconsistencies of the standard model, including a simultaneous resolution of the Hubble and $\sigma_8$ tensions. To assess the viability of the model, we set initial conditions compatible to the Planck 2018 best fit $\Lambda$CDM cosmology and fit its additional parameters using SN~Ia observations from DESY5 and a sample of uncorrelated $f\sigma_8$ measurements. Our findings show that backreaction effects from the cosmic web could restore the concordance between early and late Universe cosmological probes., Comment: 7 Figures, 8 pages + appendix and references. To be submitted to Physical Review. Comments are very welcome!
Published: 2024

8. Optimizing Multi-Task Learning for Accurate Spacecraft Pose Estimation

Author: Evangelisti, Francesco, Rossi, Francesco, Giani, Tobia, Bloise, Ilaria, and Varile, Mattia
Subjects: Computer Science - Machine Learning
Abstract: Accurate satellite pose estimation is crucial for autonomous guidance, navigation, and control (GNC) systems in in-orbit servicing (IOS) missions. This paper explores the impact of different tasks within a multi-task learning (MTL) framework for satellite pose estimation using monocular images. By integrating tasks such as direct pose estimation, keypoint prediction, object localization, and segmentation into a single network, the study aims to evaluate the reciprocal influence between tasks by testing different multi-task configurations thanks to the modularity of the convolutional neural network (CNN) used in this work. The trends of mutual bias between the analyzed tasks are found by employing different weighting strategies to further test the robustness of the findings. A synthetic dataset was developed to train and test the MTL network. Results indicate that direct pose estimation and heatmap-based pose estimation positively influence each other in general, while both the bounding box and segmentation tasks do not provide significant contributions and tend to degrade the overall estimation accuracy.
Published: 2024
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9. A Framework for Evaluating PM2.5 Forecasts from the Perspective of Individual Decision Making

Author: Berlinghieri, Renato, Burt, David R., Giani, Paolo, Fiore, Arlene M., and Broderick, Tamara
Subjects: Computer Science - Machine Learning, Physics - Atmospheric and Oceanic Physics
Abstract: Wildfire frequency is increasing as the climate changes, and the resulting air pollution poses health risks. Just as people routinely use weather forecasts to plan their activities around precipitation, reliable air quality forecasts could help individuals reduce their exposure to air pollution. In the present work, we evaluate several existing forecasts of fine particular matter (PM2.5) within the continental United States in the context of individual decision-making. Our comparison suggests there is meaningful room for improvement in air pollution forecasting, which might be realized by incorporating more data sources and using machine learning tools. To facilitate future machine learning development and benchmarking, we set up a framework to evaluate and compare air pollution forecasts for individual decision making. We introduce a new loss to capture decisions about when to use mitigation measures. We highlight the importance of visualizations when comparing forecasts. Finally, we provide code to download and compare archived forecast predictions., Comment: 22 pages, 3 figures
Published: 2024

10. Anomaly Detection for Real-World Cyber-Physical Security using Quantum Hybrid Support Vector Machines

Author: Cultice, Tyler, Onim, Md. Saif Hassan, Giani, Annarita, and Thapliyal, Himanshu
Subjects: Quantum Physics, Computer Science - Cryptography and Security, Computer Science - Machine Learning
Abstract: Cyber-physical control systems are critical infrastructures designed around highly responsive feedback loops that are measured and manipulated by hundreds of sensors and controllers. Anomalous data, such as from cyber-attacks, greatly risk the safety of the infrastructure and human operators. With recent advances in the quantum computing paradigm, the application of quantum in anomaly detection can greatly improve identification of cyber-attacks in physical sensor data. In this paper, we explore the use of strong pre-processing methods and a quantum-hybrid Support Vector Machine (SVM) that takes advantage of fidelity in parameterized quantum circuits to efficiently and effectively flatten extremely high dimensional data. Our results show an F-1 Score of 0.86 and accuracy of 87% on the HAI CPS dataset using an 8-qubit, 16-feature quantum kernel, performing equally to existing work and 14% better than its classical counterpart., Comment: 6 pages, 5 figures, 2 tables, under ISVLSI 2024 proceedings
Published: 2024

11. Utilization of Agro-Industrial Residues in the Rearing and Nutritional Enrichment of Zophobas atratus Larvae: New Food Raw Materials

Author: Renata Quartieri Nascimento, Cláudio Vaz Di Mambro Ribeiro, Nelson Barros Colauto, Larissa da Silva, Paulo Vitor França Lemos, Ederlan de Souza Ferreira, Giani Andrea Linde, Bruna Aparecida Souza Machado, Pedro Paulo Lordelo Guimarães Tavares, Aline Camarão Telles Biasoto, Marcelo Andres Umsza Guez, Natália Carvalho, Denílson de Jesus Assis, Jania Betânia Alves da Silva, and Carolina Oliveira de Souza
Subjects: Zophobas morio, food conversion, by-product, insect, sustainability, Organic chemistry, QD241-441
Abstract: Edible insects are a potential alternative food source of high feed conversion efficiency and protein content. Zophobas atratus is an edible insect that adapts to different diets, enabling sustainable rearing by adding value to by-products and agro-industrial residues. This study aimed to evaluate the performance and nutritional characterization of Zophobas atratus larvae fed with different proportions of grape residue. Physicochemical analysis of the diets and larvae (AOAC procedures), fatty acid profile (chromatographic techniques), metals and non-metals (inductively coupled plasma optical emission spectrometry), larval mass gain, feed conversion efficiency, and mortality rate were assessed. The replacement of 25% of the conventional diet with grape residue increased lipid, ash, and fiber contents and reduced protein, carbohydrates, and energy. It promoted greater mass gain, lower mortality rate, and reduced larval growth time by 51%. Among the replacements, 25% resulted in the second-highest content of calcium, sodium, magnesium, and zinc, and the lowest content of potassium and phosphorus in the larvae. The 100% replacement resulted in the highest amounts of C18:2n6 (27.8%), C18:3n3 (2.2%), and PUFA (30.0%). Replacing 25% of the conventional diet with grape residue is equivalent to the conventional diet in many aspects and improves several larvae performance indices and nutritional values.
Published: 2022
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12. Geant4: a Game Changer in High Energy Physics and Related Applicative Fields

Author: Basaglia, Tullio, Bell, Zane W., D'Agostino, Daniele, Dressendorfer, Paul V., Giani, Simone, Pia, Maria Grazia, and Saracco, Paolo
Subjects: Physics - Computational Physics, High Energy Physics - Phenomenology
Abstract: Geant4 is an object-oriented toolkit for the simulation of the passage of particles through matter. Its development was initially motivated by the requirements of physics experiments at high energy hadron colliders under construction in the last decade of the 20th century. Since its release in 1998, it has been exploited in many different applicative fields, including space science, nuclear physics, medical physics and archaeology. Its valuable support to scientific discovery is demonstrated by more than 16000 citations received in the past 25 years, including notable citations for main discoveries in different fields. This accomplishment shows that well designed software plays a key role in enabling scientific advancement. In this paper we discuss the key principles and the innovative decisions at the basis of Geant4, which made it a game changer in high energy physics and related fields, and outline some considerations regarding future directions., Comment: Accepted for publication in Future Generation Computer Systems
Published: 2024

13. Mapping the SMEFT at High-Energy Colliders: from LEP and the (HL-)LHC to the FCC-ee

Author: Celada, Eugenia, Giani, Tommaso, ter Hoeve, Jaco, Mantani, Luca, Rojo, Juan, Rossia, Alejo N., Thomas, Marion O. A., and Vryonidou, Eleni
Subjects: High Energy Physics - Phenomenology, High Energy Physics - Experiment
Abstract: We present SMEFiT3.0, an updated global SMEFT analysis of Higgs, top quark, and diboson production data from the LHC complemented by electroweak precision observables (EWPOs) from LEP and SLD. We consider recent inclusive and differential measurements from the LHC Run II, alongside with a novel implementation of the EWPOs based on independent calculations of the relevant EFT contributions. We estimate the impact of HL-LHC measurements on the SMEFT parameter space when added on top of SMEFiT3.0, through dedicated projections extrapolating from Run II data. We quantify the significant constraints that measurements from two proposed high-energy circular $e^+e^-$ colliders, the FCC-ee and the CEPC, would impose on both the SMEFT parameter space and on representative UV-complete models. Our analysis considers projections for the FCC-ee and the CEPC based on the latest running scenarios and includes $Z$-pole EWPOs, fermion-pair, Higgs, diboson, and top quark production, using optimal observables for both the $W^+W^-$ and the $t\bar{t}$ channels. The framework presented in this work may be extended to other future colliders and running scenarios, providing timely input to ongoing studies towards future high-energy particle physics facilities., Comment: 72 pages, 22 figures
Published: 2024

14. Bayesian Inference with Gaussian Processes for the Determination of Parton Distribution Functions

Author: Candido, Alessandro, Del Debbio, Luigi, Giani, Tommaso, and Petrillo, Giacomo
Subjects: High Energy Physics - Phenomenology, High Energy Physics - Lattice
Abstract: We discuss a Bayesian methodology for the solution of the inverse problem underlying the determination of parton distribution functions (PDFs). In our approach, Gaussian Processes (GPs) are used to model the PDF prior, while Bayes theorem is used in order to determine the posterior distribution of the PDFs given a set of data. We discuss the general formalism, the Bayesian inference at the level of both parameters and hyperparameters, and the simplifications which occur when the observable entering the analysis is linear in the PDF. We benchmark the new methodology in two simple examples for the determination of a single PDF flavor from a set of Deep Inelastic Scattering (DIS) data and from a set of equal-time correlators computed using lattice QCD. We discuss our results, showing how the proposed methodology allows for a well-defined statistical interpretation of the different sources of errors entering the PDF uncertainty, and how results can be validated a posteriori.
Published: 2024

15. Hydrogels from non-woody lignocellulosic biomass for toxic metal uptake from wastewater: a brief overview

Author: Brião, Giani de Vargas, Rosa, Derval S., and Frollini, Elisabete
Published: 2024
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16. University and Higher Education: a Clockwork in Perpetual Motion

Author: Giani, Ludovica and Olivari, Carlotta
Published: 2024
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17. Abdominal drainage after minimally invasive distal pancreatectomy: out of sight, out of mind?

Author: Mazzola, Michele, Benedetti, Antonio, Giani, Alessandro, Calcagno, Pietro, Zironda, Andrea, Paterno, Michele, Giacomoni, Alessandro, De Martini, Paolo, and Ferrari, Giovanni
Published: 2024
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18. Mycelial biomass cultivation of Lentinus crinitus

Author: Itaruã Machri Colla, Olavo Bilac Quaresma de Oliveira Filho, Janyeli Dorini Silva de Freitas, Míria Benetati Delgado Bertéli, Giani Andrea Linde, Juliana Silveira do Valle, and Nelson Barros Colauto
Subjects: Axenic cultivation., Soybean., Urea., Mycelial biomass growth., Cultivation condition., Agriculture, Biology (General), QH301-705.5
Abstract: Lentinus crinitus is a medicinal basidiomycete, little studied regarding the basic cultivation conditions, which is used in bioremediation and consumed by native Indians from the Brazilian Amazon. Also, it produces a fungal secondary metabolite panepoxydone that has been described as an essential regulator of the inflammatory and immune response. This study aimed to evaluate basic conditions of temperature, pH, and nitrogen concentration and source in the cultivation of L. crinitus mycelial biomass. In order to evaluate fungal growth temperature, 2% malt extract agar (MEA) medium, pH 5.5, was utilized from 19 to 40 °C. For pH, MEA had pH adjusted from 2 to 11 and cultivated at 28 °C. Urea or soybean meal was added to MEA to obtain final concentration from 0.5 and 16 g/L of nitrogen, pH of 5.5, cultivated at 28 °C. The best temperature growth varies from 31 to 34 ºC and the optimal one is 32.7º C, and the best pH ranges from 4.5 to 6.5 and the optimal one is 6.1. Protein or non-protein nitrogen concentration is inversely proportional to the mycelial biomass growth. Nitrogen concentrations of 2.0 g/L soybean meal and urea inhibit mycelial biomass growth in 11% and 12%, respectively, but high concentrations of 16.0 g/L nitrogen inhibit the growth in 46% and 95%, respectively. The fungus is robust and grows under extreme conditions of temperature and pH, but smaller adaptation with increasing nitrogen concentrations in the cultivation medium, mainly non-protein nitrogen.
Published: 2020

19. Caracterização dos genes de cepas de Bradyrhizobium spp. contrastantes quanto à eficiência de fixação biológica de nitrogênio em soja

Author: Camila de Medeiros, Gilberto Aguiar Pereira, Janyeli Dorini Silva de Freitas, Olavo Bilac Quaresma de Oliveira Filho, Juliana Silveira do Valle, Giani Andrea Linde, Luzia Doretto Paccola-Meirelles, Nelson Barros Colauto, and Fernando Gomes Barcellos
Subjects: Bradyrhizobium, Rizobactérias, PCR-RFLP, Polimorfismo de restrição., Agriculture (General), S1-972
Abstract: Bactérias do gênero Bradyrhizobium podem estabelecer simbiose com a soja e suprir a demanda de nitrogênio pela fixação biológica de nitrogênio (FBN). Este estudo teve como objetivo caracterizar genes relacionados à eficiência na FBN em cepas de B. japonicum contrastantes quanto a eficiência na FBN. As sequências gênicas relacionadas à eficiência da FBN em soja foram previamente identificadas na cepa S370 de B. japonicum utilizando uma técnica de DNA subtrativo. Os genes foram amplificados com iniciadores construídos a partir do genoma da cepa USDA 110. Os produtos de PCR foram digeridos com endonucleases de restrição e os produtos de RFLP foram analisados por eletroforese horizontal. Dos quatro genes estudados, apenas blr 3208 e blr 4511 amplificaram na maioria das cepas. Não foi observado polimorfismo no perfil de restrição dos genes blr 3208 e blr 4511 por PCR-RFLP. As cepas contrastantes tiveram os genes blr 3208 e blr 4511 sequenciados e a comparação das sequências nucleotídicas por análise de alinhamento múltiplo mostrou a presença de regiões internas preservadas, confirmando a análise realizada por PCR-RFLP. Os genes blr 3208 e blr 4511 são altamente conservados entre as cepas de B. japonicum, o que pode estar relacionado à função adaptativa durante o processo evolutivo do gênero Bradyrhizobium.
Published: 2020
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20. Iron Or Zinc Bioaccumulated In Mycelial Biomass Of Edible Basidiomycetes

Author: SUZANA H. UMEO, MARIA GRACIELA I. FARIA, DOUGLAS C. DRAGUNSKI, JULIANA S. DO VALLE, NELSON B. COLAUTO, and GIANI ANDREA LINDE
Subjects: Basidiomycota, bioaccumulation, edible mushroom, mycelial biomass, Science
Abstract: Abstract Iron and zinc bioaccumulation in mycelial biomass of different medicinal basidiomycetes was evaluated in order to produce metal-enriched mycelial biomass as an alternative functional food from non-animal sources and based on biotechnology processes. Pleurotus ostreatus strain U2-9, U2-11, U6-8, and U6-9, Pleurotus eryngii strain U8-11, Schizophyllum commune strain U6-7, and Lentinula edodes strain U6-11 and U6-12 were grown in malt extract agar with or without addition of 50 mg/L iron or 7.5 mg/L zinc. The mycelial biomass was separated and iron and zinc concentrations were determined in a flame atomic absorption spectrophotometer. Basidiomycete strains presented different growth rates with the presence of iron and zinc; there was no dependence between the metal bioaccumulation and the fungal growth. The fungi presented greater capacity to bioaccumulate iron than zinc. P. ostreatus (U2-9) has greater iron bioaccumulation (3197.7 mg/kg) while P. ostreatus (U6-8) greater zinc bioaccumulation (440.4 mg/kg) in mycelial biomass. P. ostreatus (U2-9), P. ostreatus (U2-11), and S. commune (U6-7) had the highest metal translocation rates from the culture medium to mycelial biomass. The mycelial biomass enriched with iron or zinc is an alternative to a new functional food from non-animal sources.
Published: 2020
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21. Lentinus crinitus response to blue light on carbohydrate-active enzymes

Author: Renan Alberto Marim, Katielle Vieira Avelino, Marisangela Isabel Wietzikoski Halabura, Nelma Lopes Araújo, Thiago Teodoro Santana, Giani Andrea Linde, Nelson Barros Colauto, and Juliana Silveira do Valle
Subjects: Cellulase., Hemicellulase., Lentinus crinitus., Polygalacturonase., Visible light wavelengths, White-rot fungi., Agriculture, Biology (General), QH301-705.5
Abstract: Fungi are capable of sensing light from ultraviolet to far-red and they use light as a source of information about the environment anticipating stress and adverse conditions. Lentinus crinitus is a lignin-degrading fungus which produces laccase and other enzymes of biotechnological interest. The effect of blue light on fungal enzymatic activity has been studied; however, it has not been found studies on the effect of the blue light on carbohydrate-active enzymes and on mycelial biomass production of L. crinitus. We aimed to investigate carbohydrate-active enzymes activity and mycelial biomass production of L. crinitus cultivated under continuous illumination with blue light. L. crinitus was cultivated in malt extract medium in the dark, without agitation, and under continuous illumination with blue light-emitting diodes. The blue light reduced the total cellulase, pectinase and xylanase activities but increased the endoglucanase activity. Blue light reduced the mycelial growth of L. crinitus in 26% and the enzymatic activity-to-mycelial biomass ratio (U mg-1 dry basis) increased in 10% total cellulase, 33% endoglucanase, and 16% pectinase activities. Also, it is suggested that L. crinitus has a photosensory system and it could lead to new process of obtaining enzymes of biotechnological interest.
Published: 2020

22. The Path to N$^3$LO Parton Distributions

Author: The NNPDF Collaboration, Ball, Richard D., Barontini, Andrea, Candido, Alessandro, Carrazza, Stefano, Cruz-Martinez, Juan, Del Debbio, Luigi, Forte, Stefano, Giani, Tommaso, Hekhorn, Felix, Kassabov, Zahari, Laurenti, Niccolò, Magni, Giacomo, Nocera, Emanuele R., Rabemananjara, Tanjona R., Rojo, Juan, Schwan, Christopher, Stegeman, Roy, and Ubiali, Maria
Subjects: High Energy Physics - Phenomenology, High Energy Physics - Experiment
Abstract: We extend the existing leading (LO), next-to-leading (NLO), and next-to-next-to-leading order (NNLO) NNPDF4.0 sets of parton distribution functions (PDFs) to approximate next-to-next-to-next-to-leading order (aN$^3$LO). We construct an approximation to the N$^3$LO splitting functions that includes all available partial information from both fixed-order computations and from small and large $x$ resummation, and estimate the uncertainty on this approximation by varying the set of basis functions used to construct the approximation. We include known N$^3$LO corrections to deep-inelastic scattering structure functions and extend the FONLL general-mass scheme to $\mathcal{O}\left( \alpha_s^3\right)$ accuracy. We determine a set of aN$^3$LO PDFs by accounting both for the uncertainty on splitting functions due to the incomplete knowledge of N$^3$LO terms, and to the uncertainty related to missing higher corrections (MHOU), estimated by scale variation, through a theory covariance matrix formalism. We assess the perturbative stability of the resulting PDFs, we study the impact of MHOUs on them, and we compare our results to the aN$^3$LO PDFs from the MSHT group. We examine the phenomenological impact of aN$^3$LO corrections on parton luminosities at the LHC, and give a first assessment of the impact of aN$^3$LO PDFs on the Higgs and Drell-Yan total production cross-sections. We find that the aN$^3$LO NNPDF4.0 PDFs are consistent within uncertainties with their NNLO counterparts, that they improve the description of the global dataset and the perturbative convergence of Higgs and Drell-Yan cross-sections, and that MHOUs on PDFs decrease substantially with the increase of perturbative order., Comment: 63 pages, 41 figures. Final version, as published in EPJC. Various clarifications added. Fig 2.9 and Tab. 4.6, 5.1 and 5.2 added. In particular, comparison to approximate YR4 estimate of PDF uncertainties added (Tab 4.1, 4.2 and associate discussion in sect. 5)
Published: 2024

23. Determination of the theory uncertainties from missing higher orders on NNLO parton distributions with percent accuracy

Author: The NNPDF Collaboration, Ball, Richard D., Barontini, Andrea, Candido, Alessandro, Carrazza, Stefano, Cruz-Martinez, Juan, Del Debbio, Luigi, Forte, Stefano, Giani, Tommaso, Hekhorn, Felix, Kassabov, Zahari, Laurenti, Niccolò, Magni, Giacomo, Nocera, Emanuele R., Rabemananjara, Tanjona R., Rojo, Juan, Schwan, Christopher, Stegeman, Roy, and Ubiali, Maria
Subjects: High Energy Physics - Phenomenology
Abstract: We include uncertainties due to missing higher order corrections to QCD computations (MHOU) used in the determination of parton distributions (PDFs) in the recent NNPDF4.0 set of PDFs. We use our previously published methodology, based on the treatment of MHOUs and their full correlations through a theory covariance matrix determined by scale variation, now fully incorporated in the new NNPDF theory pipeline. We assess the impact of the inclusion of MHOUs on the NNPDF4.0 central values and uncertainties, and specifically show that they lead to improved consistency of the PDF determination with an ensuing moderate reduction of PDF uncertainties at NNLO., Comment: 23 pages, 6 figures. Final version, as published in EPJC. Several small improvements; expanded discussion of the phi indicator in sect 4.2
Published: 2024

24. Photons in the proton: implications for the LHC

Author: The NNPDF Collaboration, Ball, Richard D., Barontini, Andrea, Candido, Alessandro, Carrazza, Stefano, Cruz-Martinez, Juan, Del Debbio, Luigi, Forte, Stefano, Giani, Tommaso, Hekhorn, Felix, Kassabov, Zahari, Laurenti, Niccolò, Magni, Giacomo, Nocera, Emanuele R., Rabemananjara, Tanjona R., Rojo, Juan, Schwan, Christopher, Stegeman, Roy, and Ubiali, Maria
Subjects: High Energy Physics - Phenomenology
Abstract: We construct a set of parton distribution functions (PDFs), based on the recent NNPDF4.0 PDF set, that also include a photon PDF. The photon PDF is constructed using the LuxQED formalism, while QED evolution accounting for O(alpha), O(alpha alphas) and O(alpha^2) corrections is implemented and benchmarked by means of the EKO code. We investigate the impact of QED effects on NNPDF4.0, and compare our results both to our previous NNPDF3.1QED PDF set and to other recent PDF sets that include the photon. We assess the impact of photon-initiated processes and electroweak corrections on a variety of representative LHC processes, and find that they can reach the 5% level in vector boson pair production at large invariant mass., Comment: 32 pages, 19 figures. Final; version, as published on EPJC. Pheno discussion in Sect 4.2 improved, a few typos corrected
Published: 2024

25. Red Tomato Products as an Alternative to Reduce Synthetic Dyes in the Food Industry: A Review

Author: Tiago Alves Castro, Bruna Santos Leite, Larissa Santos Assunção, Tayane de Jesus Freitas, Nelson Barros Colauto, Giani Andrea Linde, Deborah Murowaniecki Otero, Bruna Aparecida Souza Machado, and Camila Duarte Ferreira Ribeiro
Subjects: natural food additive, antioxidant activity, lycopene, food pigment, carotenes, Organic chemistry, QD241-441
Abstract: Most dyes used in the food industry are synthetic and can be a health hazard. Red tomato may serve as a natural alternative dye to replace synthetic colorants. This study aimed to review the literature on the addition of red tomato products (powder tomato, paste, freeze-dried, tomato peel powder, tomato pomace) to reduce the usage of synthetic dyes in the food industry. Red tomato products have been used as coloring in pasta, bologna, sausages, cookies, crackers, macaroons, hamburgers, breads, muffins, cheeses, and nuggets. The trans-cis isomerization of lycopene by oxidative processes directly affects the color of the pigment. The lycopene contained in tomato has antioxidant activity and could reduce or eliminate other oxidants and/or synthetic preservatives in food. Moreover, tomatoes in foods have high sensory scores, nutritional appeal, and marketing potential. However, its use as a food colorant has been not extensively explored. Therefore, further studies are still required, especially on the stability of carotenoids in tomatoes used in processed foods.
Published: 2021
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26. Schinus terebinthifolius essential oil and fractions in the control of Aedes aegypti

Author: Wanessa de Campos Bortolucci, Herika Line Marko de Oliveira, Eloísa Schineider Silva, Caio Franco de Araújo Almeida Campo, José Eduardo Gonçalves, Ranulfo Piau Junior, Nelson Barros Colauto, Giani Andrea Linde, and Zilda Cristiani Gazim
Subjects: larval immersion test, acetylcholinesterase, bicyclogermacrene, rose pepper, germacrene d., Agriculture, Biology (General), QH301-705.5
Abstract: Several technologies have been developed to control Aedes aegypti, mainly studies on isolated plant molecules. The Schinus terebinthifolius (Raddi) (Anacardiaceae), popularly known as pink pepper is a plant widely used in reforestation of degraded areas and its fruits are used as condiments. The objective of this work was to investigate the potential of essential oils (EOs) and fractions (FRs) obtained from fresh fruits and leaves of S. terebinthifolius. The EOs were obtained by hydrodistillation (2 hours), fractionated on a chromatographic column using as the stationary phase silica gel 60 (0.063-0.2mm), mobile phases: n-hexane, dichloromethane, ethyl acetate and methanol and chemically evaluated by gas chromatography coupled to mass spectrometer (GC/MS). EOs and FRs were tested against larvae of the third stage and pupae of Ae. aegypti by Immersion Test at concentrations ranging from 500.00 to 0.003 mg mL-1 (v/v). The hexane FRs obtained from fruits and leaves were the ones that showed the greatest activity on the larvae (LC99.9= 0.60 mg mL-1 and LC99.9 0.64 mg mL-1, respectively) and pupae (LC99,9 = 2.51 mg mL-1 and 2.61 mg mL-1, respectively). These results were confirmed by the anticholinesterase activity where the hexane (fruit and leaf) FRs presented the highest inhibitory potential on the acetylcholinesterase enzyme (0.156 mg mL-1 and 0.312 mg mL-1, respectively), suggesting the likely mechanism of action. The larvicidal potential can be explained by the presence of the major compounds bicyclogermacrene and germacrene D in the hexane FRs, indicating in this way that they may replace or even act in synergisms with conventional chemical larvicides. In this way the present study opens the field for new researches, aiming the development of products with the compounds bicyclogermacrene and germacrene D, as an alternative in the control of this culicide.
Published: 2019
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27. Iron and zinc mycelial bioaccumulation in Agaricus subrufescens strains

Author: Suzana Harue Umeo, Maria Graciela Iecher Faria, Simone Schenkel Scheid Vilande, Douglas Cardoso Dragunski, Juliana Silveira do Valle, Nelson Barros Colauto, and Giani Andrea Linde
Subjects: Agaricus blazei, Agaricus brasiliensis, Iron, Metal, Mycelia, Translocation., Agriculture (General), S1-972
Abstract: Agaricus subrufescens, a basidiomycete native to Brazil, is worldwide cultivated due to its medicinal properties. This fungus is capable of bioaccumulating metals in the mycelial biomass when cultured in the presence of them; however, this capacity is little explored for functional food production. This study aimed to evaluate the amount of iron or zinc bioaccumulated in the vegetative mycelium of sixteen strains of A. subrufescens. Mycelia were grown in malt extract agar added with 50 mg/L of iron or with 7.5 mg/L of zinc. The metal bioaccumulation in the mycelial biomass was strain-dependent. In general, metal can inhibit or stimulate the mycelial growth ranging from -81 to +78% for iron and from -86 to +100% for zinc. The highest bioaccumulated iron and zinc concentrations in the mycelial biomass was 2,595.65 mg/kg and 1,655.83 mg/kg, respectively and occurred in the U4-4 strain. The supplementation of mycelial biomass using iron or zinc is an alternative to develop food supplements, that can be used both in the human and animal diet and in the prevention of diseases.
Published: 2019
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28. Bioinsecticide potential of Curcuma zedoaria rhizome essential oil

Author: Herika Line Marko de Oliveira, Wanessa de Campos Bortolucci, Eloísa Schneider Silva, Caio Franco de Araújo Almeida Campos, José Eduardo Gonçalves, Ranulfo Piau Júnior, Giani Andréa Linde, and Zilda Cristiani Gazim
Subjects: aedes aegypti, anticholinesterase, epicurzerenone, β-elemene, lethal concentration (lc)., 1,8 cineole, Agriculture, Biology (General), QH301-705.5
Abstract: In this study the potential bioinseticide of the essential oil (OE) extracted from the rhizomes of the species Curcuma zedoaria (Zingiberaceae) was evaluated. The rhizomes were collected during dormancy (winter) and budding (summer). The EO was obtained by hydrodistillation (2h) and identified by GC/MS. In addition, a multivariate exploratory analysis was done to determine the analysis of the major compounds (PCA). The EO yield in dormancy was 0.61± 0.07 (%) and in budding 0.55 ± 0.08 (%). The bioassays on Aedes aegypti larvae and pupae were done by immersion test at different EO concentrations which ranged from 500.00 to 0.003 mg mL-1 (v/v). The results on the larvae and pupae indicated LC99.9 of (0.01 and 1.38 mg mL-1) for EO in dormancy, and (0.08 and 2.63 mg mL-1) for EO during budding, respectively. The action mechanism of EOs in both periods was determined by autobiographic method evaluating the inhibitory potential on the acetylcholinesterase enzyme, indicating greater inhibition of the EO enzyme during dormancy (0.039 mg mL-1) when compared to the EO during budding (0.156 mg mL-1). The projection representation of the EO chemical classes in both evaluated periods indicated that oxygenated sesquiterpenes are the major compound class (46.99% in dormancy) and (43.59% in budding). The projection of major chemical compounds of EOs presented three compounds with greater mass flow distancing: epicurzerenone (18.20% and 12.10%); 1.8 cineole (15.76% and 12.10%) and β-elemene (4.43 and 0.01%) that are found in greater amounts in the dormancy EO when compared to budding, respectively. These results corroborate with the greater potential on Ae. aegypti larvae and pupae found for the dormancy EO. The results are promising because they show in which vegetative cycle phase C. zedoaria EO presents greater bioinsecticide potential.
Published: 2019
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29. Antimicrobial Activity of Essential Oil of Baccharis dracunculifolia DC (Asteraceae) Aerial Parts at Flowering Period

Author: Luciane Neris Cazella, Jasmina Glamoclija, Marina Soković, José Eduardo Gonçalves, Giani Andrea Linde, Nelson Barros Colauto, and Zilda Cristiani Gazim
Subjects: alecrim-do-campo, vassourinha, GC–MS, inhibiting activity, Staphylococcus aureus, Bacillus cereus, Plant culture, SB1-1110
Abstract: Baccharis dracunculifolia DC (Asteraceae) is a Brazilian native bush tree, and its leaf essential oil has been reported to possess some biological activities, but the antimicrobial activity of its aerial part essential oil at the flowering period is unknown or little studied, mainly against agents that cause foodborne diseases. Thus, this study aimed to determine the chemical composition and evaluate the antimicrobial activity of the essential oil of B. dracunculifolia aerial part at flowering period. This essential oil was obtained by hydro distillation and its chemical composition was determined by gas chromatography coupled with mass spectrometry (GC–MS). The minimum inhibitory concentration, minimum bactericidal concentration, and minimum fungicidal concentration of the essential oil were evaluated against eight bacteria and eight fungi using 96-well microtiter plates. The essential oil yield was 1.8 ± 0.07%, and spathulenol (27%) and trans-nerolidol (23%), both oxygenated sesquiterpenes, were the major compounds found among 30 chemical constituents identified. The essential oil presented bacteriostatic and bactericidal activities, mainly against Staphylococcus aureus, Bacillus cereus and Pseudomonas aeruginosa, and also fungistatic and fungicidal activities. However, its antibacterial activity was more effective than the antifungal one by using the essential oil at lower concentrations. Essential oil of B. dracunculifolia may be a potential alternative for food applications in order to reduce synthetic chemicals in a more sustainable food industry.
Published: 2019
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30. Subretinal transient hyporeflectivity in neovascular age-related macular degeneration and its response to a loading phase of aflibercept: PRECISE report 4

Author: Montesel, Andrea, Pakeer Muhammed, Raheeba, Chandak, Swati, Kazantzis, Dimitrios, Thottarath, Sridevi, Chandra, Shruti, Chong, Victor, Burton, Benjamin J. L., Menon, Geeta, Pearce, Ian, McKibbin, Martin, Kotagiri, Ajay, Talks, James, Grabowska, Anna, Ghanchi, Faruque, Gale, Richard, Giani, Andrea, Yamaguchi, Taffeta Ching Ning, and Sivaprasad, Sobha
Published: 2024
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31. The Impact of Economic Behavior Environment: A Comparative Study Among EU’s Countries and China

Author: Gradinaru, Giani Ionel and Maricut, Alin-Cristian
Published: 2024
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32. Cereal bar enriched with ora-pro-nóbis (Pereskia aculeata Miller): physicochemical and sensory characterization

Author: da Cruz, Gabriela Silva, da Silva, Clara Nóvoa Pinto, Gomes-Junior, Erival Amorim, de Souza, Thaís Luz, Latif, Abdon Luiz Ornelas, Maciel, Leonardo Fonseca, Santos, Luís Fernandes Pereira, Linde, Giani Andrea, Colauto, Nelson Barros, Menezes-Filho, Jose Antonio, de Jesus Benevides, Clícia Maria, and Pinto, Laise Cedraz
Published: 2024
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33. Prone-position decreases airway closure in a patient with ARDS undergoing venovenous extracorporeal membrane oxygenation

Author: Giani, Marco, Restivo, Andrea, Raimondi Cominesi, Davide, Fracchia, Rosa, Pozzi, Matteo, Del Sorbo, Lorenzo, Foti, Giuseppe, Brochard, Laurent, and Rezoagli, Emanuele
Published: 2024
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34. ROBIN: a randomised, double-masked, placebo-controlled Phase IIa study of the AOC3 inhibitor BI 1467335 in diabetic retinopathy

Author: Dong Nguyen, Quan, Ehlers, Justis P., Boyer, David S., Jin, Xidong, Giani, Andrea, and Ehrlich, Michael S.
Published: 2024
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35. Ultralight Dark Matter Search with Space-Time Separated Atomic Clocks and Cavities

Author: Filzinger, Melina, Caddell, Ashlee R., Jani, Dhruv, Steinel, Martin, Giani, Leonardo, Huntemann, Nils, and Roberts, Benjamin M.
Subjects: High Energy Physics - Phenomenology, Astrophysics - Cosmology and Nongalactic Astrophysics, Physics - Atomic Physics
Abstract: We devise and demonstrate a method to search for non-gravitational couplings of ultralight dark matter to standard model particles using space-time separated atomic clocks and cavity-stabilized lasers. By making use of space-time separated sensors, which probe different values of an oscillating dark matter field, we can search for couplings that cancel in typical local experiments. This provides sensitivity to both the temporal and spatial fluctuations of the field. We demonstrate this method using existing data from a frequency comparison of lasers stabilized to two optical cavities connected via a 2220 km fiber link [Schioppo et al., Nat. Commun. 13, 212 (2022)], and from the atomic clocks on board the Global Position System satellites. Our analysis results in constraints on the coupling of scalar dark matter to electrons, d_me, for masses between 1e-19 eV/c^2 and 2e-15 eV/c^2. These are the first constraints on d_me alone in this mass range., Comment: 7 pages, 2 figures
Published: 2023

36. The intrinsic charm quark valence distribution of the proton

Author: Ball, Richard D., Candido, Alessandro, Cruz-Martinez, Juan, Forte, Stefano, Giani, Tommaso, Hekhorn, Felix, Magni, Giacomo, Nocera, Emanuele R., Rojo, Juan, and Stegeman, Roy
Subjects: High Energy Physics - Phenomenology, High Energy Physics - Experiment
Abstract: We provide a first quantitative indication that the wave function of the proton contains unequal distributions of charm quarks and antiquarks, i.e. a nonvanishing intrinsic valence charm distribution. A significant nonvanishing valence component cannot be perturbatively generated, hence our results reinforce previous evidence that the proton contains an intrinsic (i.e., not radiatively generated) charm quark component. We establish our result through a determination of the parton distribution functions (PDFs) of charm quarks and antiquarks in the proton. We propose two novel experimental probes of this intrinsic charm valence component: D-meson asymmetries in Z+c-jet production at the LHCb experiment, and flavor-tagged structure functions at the Electron-Ion Collider., Comment: 11 pages, 11 figures. PDF files available for download in LHAPDF format from https://nnpdf.mi.infn.it/nnpdf4-0-charm-asymmetry-study/ Final version, to be published in PRD (letters). Figures 2, 6 and 7 added. Fit without imposing the charm valence sum rule added. Various small clarifications
Published: 2023

37. An effective description of Laniakea: impact on cosmology and the local determination of the Hubble constant

Author: Giani, L., Howlett, C., Said, K., Davis, T., and Vagnozzi, S.
Subjects: Astrophysics - Cosmology and Nongalactic Astrophysics, General Relativity and Quantum Cosmology
Abstract: We propose an effective model to describe the bias induced on cosmological observables by Laniakea, the gravitational supercluster hosting the Milky Way, which was defined using peculiar velocity data from Cosmicflows-4 (CF4). The structure is well described by an ellipsoidal shape exhibiting triaxial expansion, reasonably approximated by a constant expansion rate along the principal axes. Our best fits suggest that the ellipsoid, after subtracting the background expansion, contracts along the two smaller axes and expands along the longest one, predicting an average expansion of $\sim -1.1 ~\rm{km}/\rm{s}/\rm{Mpc}$. The different expansion rates within the region, relative to the mean cosmological expansion, induce line-of-sight-dependent corrections in the computation of luminosity distances. We apply these corrections to two low-redshift datasets: the Pantheon+ catalog of type Ia Supernovae (SN~Ia), and 63 measurements of Surface Brightness Fluctuations (SBF) of early-type massive galaxies from the MASSIVE survey. We find corrections on the distances of order $\sim 2-3\%$, resulting in a shift in the inferred best-fit values of the Hubble constant $H_0$ of order $\Delta H_0^{\rm{SN~Ia}}\approx 0.5 ~\rm{km}/\rm{s}/\rm{Mpc}$ and $\Delta H_0^{\rm{SBF}}\approx 1.1 ~\rm{km}/\rm{s}/\rm{Mpc}$, seemingly worsening the Hubble tension., Comment: Updated to match the published version. Eighteen pages + references, 13 figures, 1 appendix, title and abstract slightly changed. Comments are welcome!
Published: 2023
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38. The LHC as a Neutrino-Ion Collider

Author: Cruz-Martinez, Juan M, Fieg, Max, Giani, Tommaso, Krack, Peter, Mäkelä, Toni, Rabemananjara, Tanjona R, and Rojo, Juan
Subjects: Nuclear and Plasma Physics, Particle and High Energy Physics, Physical Sciences, Atomic, Molecular, Nuclear, Particle and Plasma Physics, Quantum Physics, Nuclear & Particles Physics, Astronomical sciences, Atomic, molecular and optical physics, Particle and high energy physics
Abstract: Abstract: Proton-proton collisions at the LHC generate a high-intensity collimated beam of neutrinos in the forward (beam) direction, characterised by energies of up to several TeV. The recent observation of LHC neutrinos by FASER$$u $$ ν and SND@LHC signifies that this previously overlooked particle beam is now available for scientific investigation. Here we quantify the impact that neutrino deep-inelastic scattering (DIS) measurements at the LHC would have on the parton distributions (PDFs) of protons and heavy nuclei. We generate projections for DIS structure functions for FASER$$u $$ ν and SND@LHC at Run III, as well as for the FASER$$u $$ ν 2, AdvSND, and FLArE experiments to be hosted at the proposed Forward Physics Facility (FPF) operating concurrently with the High-Luminosity LHC (HL-LHC). We determine that up to one million electron-neutrino and muon-neutrino DIS interactions within detector acceptance can be expected by the end of the HL-LHC, covering a kinematic region in x and $$Q^2$$ Q 2 overlapping with that of the Electron-Ion Collider. Including these DIS projections in global (n)PDF analyses, specifically PDF4LHC21, NNPDF4.0, and EPPS21, reveals a significant reduction in PDF uncertainties, in particular for strangeness and the up and down valence PDFs. We show that LHC neutrino data enable improved theoretical predictions for core processes at the HL-LHC, such as Higgs and weak gauge boson production. Our analysis demonstrates that exploiting the LHC neutrino beam effectively provides CERN with a “Neutrino-Ion Collider” without requiring modifications in its accelerator infrastructure.
Published: 2024

39. Extracorporeal membrane oxygenation for tuberculosis-related acute respiratory distress syndrome: An international multicentre retrospective cohort study

Author: Ait Hssain, Ali, Petit, Matthieu, Wiest, Clemens, Simon, Laura, Al-Fares, Abdulrahman A., Hany, Ahmed, Garcia-Gomez, Dafna I., Besa, Santiago, Nseir, Saad, Guervilly, Christophe, Alqassem, Wael, Lesouhaitier, Mathieu, Chelaru, Adrian, Sin, Simon WC, Roncon-Albuquerque, Jr., Roberto, Giani, Marco, Lepper, Philipp M., Lavillegrand, Jean-Rémi, Park, Sunghoon, Schellongowski, Peter, Fawzy Hassan, Ibrahim, Combes, Alain, Sonneville, Romain, and Schmidt, Matthieu
Published: 2024
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40. Mechanical ventilation settings during weaning from venovenous extracorporeal membrane oxygenation

Author: Passarelli, Maria Teresa, Petit, Matthieu, Garberi, Roberta, Lebreton, Guillaume, Luyt, Charles Edouard, Pineton De Chambrun, Marc, Chommeloux, Juliette, Hékimian, Guillaume, Rezoagli, Emanuele, Foti, Giuseppe, Combes, Alain, Giani, Marco, and Schmidt, Matthieu
Published: 2024
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41. Portable Acceleration of CMS Computing Workflows with Coprocessors as a Service

Author: Hayrapetyan, A., Tumasyan, A., Adam, W., Andrejkovic, J. W., Bergauer, T., Chatterjee, S., Damanakis, K., Dragicevic, M., Hussain, P. S., Jeitler, M., Krammer, N., Li, A., Liko, D., Mikulec, I., Schieck, J., Schöfbeck, R., Schwarz, D., Sonawane, M., Templ, S., Waltenberger, W., Wulz, C.-E., Darwish, M. R., Janssen, T., Mechelen, P. Van, Bols, E. S., D’Hondt, J., Dansana, S., De Moor, A., Delcourt, M., Faham, H. El, Lowette, S., Makarenko, I., Müller, D., Sahasransu, A. R., Tavernier, S., Tytgat, M., Onsem, G. P. Van, Putte, S. Van, Vannerom, D., Clerbaux, B., Das, A. K., De Lentdecker, G., Favart, L., Gianneios, P., Hohov, D., Jaramillo, J., Khalilzadeh, A., Khan, F. A., Lee, K., Mahdavikhorrami, M., Malara, A., Paredes, S., Thomas, L., Bemden, M. Vanden, Velde, C. Vander, Vanlaer, P., De Coen, M., Dobur, D., Hong, Y., Knolle, J., Lambrecht, L., Mestdach, G., Amarilo, K. Mota, Rendón, C., Samalan, A., Skovpen, K., Bossche, N. Van Den, Linden, J. van der, Wezenbeek, L., Benecke, A., Bethani, A., Bruno, G., Caputo, C., Delaere, C., Donertas, I. S., Giammanco, A., Jaffel, K., Jain, Sa., Lemaitre, V., Lidrych, J., Mastrapasqua, P., Mondal, K., Tran, T. T., Wertz, S., Alves, G. A., Coelho, E., Hensel, C., De Oliveira, T. Menezes, Moraes, A., Teles, P. Rebello, Soeiro, M., Júnior, W. L. Aldá, Pereira, M. Alves Gallo, Filho, M. Barroso Ferreira, Malbouisson, H. Brandao, Carvalho, W., Chinellato, J., Da Costa, E. M., Da Silveira, G. G., De Jesus Damiao, D., De Souza, S. Fonseca, De Souza, R. Gomes, Martins, J., Herrera, C. Mora, Mundim, L., Nogima, H., Pinheiro, J. P., Santoro, A., Sznajder, A., Thiel, M., Pereira, A. Vilela, Bernardes, C. A., Calligaris, L., Tomei, T. R. Fernandez Perez, Gregores, E. M., Mercadante, P. G., Novaes, S. F., Orzari, B., Padula, Sandra S., Aleksandrov, A., Antchev, G., Hadjiiska, R., Iaydjiev, P., Misheva, M., Shopova, M., Sultanov, G., Dimitrov, A., Litov, L., Pavlov, B., Petkov, P., Petrov, A., Shumka, E., Keshri, S., Thakur, S., Cheng, T., Javaid, T., Yuan, L., Hu, Z., Liu, J., Yi, K., Chen, G. M., Chen, H. S., Chen, M., Iemmi, F., Jiang, C. H., Kapoor, A., Liao, H., Liu, Z.-A., Sharma, R., Song, J. N., Tao, J., Wang, C., Wang, J., Wang, Z., Zhang, H., Agapitos, A., Ban, Y., Levin, A., Li, C., Li, Q., Mao, Y., Qian, S. J., Sun, X., Wang, D., Yang, H., Zhang, L., Zhou, C., You, Z., Lu, N., Bauer, G., Gao, X., Leggat, D., Okawa, H., Lin, Z., Lu, C., Xiao, M., Avila, C., Trujillo, D. A. Barbosa, Cabrera, A., Florez, C., Fraga, J., Vega, J. A. Reyes, Guisao, J. Mejia, Ramirez, F., Rodriguez, M., Alvarez, J. D. Ruiz, Giljanovic, D., Godinovic, N., Lelas, D., Sculac, A., Kovac, M., Sculac, T., Bargassa, P., Brigljevic, V., Chitroda, B. K., Ferencek, D., Mishra, S., Starodumov, A., Susa, T., Attikis, A., Christoforou, K., Konstantinou, S., Mousa, J., Nicolaou, C., Ptochos, F., Razis, P. A., Rykaczewski, H., Saka, H., Stepennov, A., Finger, M., Finger, Jr., M., Kveton, A., Ayala, E., Jarrin, E. Carrera, Abdelalim, A. A., Salama, E., Mahmoud, M. A., Mohammed, Y., Ehataht, K., Kadastik, M., Lange, T., Nandan, S., Nielsen, C., Pata, J., Raidal, M., Tani, L., Veelken, C., Kirschenmann, H., Osterberg, K., Voutilainen, M., Bharthuar, S., Brücken, E., Garcia, F., Kallonen, K. T. S., Kinnunen, R., Lampén, T., Lassila-Perini, K., Lehti, S., Lindén, T., Martikainen, L., Myllymäki, M., Rantanen, M.m., Siikonen, H., Tuominen, E., Tuominiemi, J., Luukka, P., Petrow, H., Besancon, M., Couderc, F., Dejardin, M., Denegri, D., Faure, J. L., Ferri, F., Ganjour, S., Gras, P., de Monchenault, G. Hamel, Lohezic, V., Malcles, J., Rander, J., Rosowsky, A., Sahin, M. Ö., Savoy-Navarro, A., Simkina, P., Titov, M., Tornago, M., Barrera, C. Baldenegro, Beaudette, F., Perraguin, A. Buchot, Busson, P., Cappati, A., Charlot, C., Chiusi, M., Damas, F., Davignon, O., De Wit, A., Alves, B. A. Fontana Santos, Ghosh, S., Gilbert, A., de Cassagnac, R. Granier, Hakimi, A., Harikrishnan, B., Kalipoliti, L., Liu, G., Motta, J., Nguyen, M., Ochando, C., Portales, L., Salerno, R., Sauvan, J. B., Sirois, Y., Tarabini, A., Vernazza, E., Zabi, A., Zghiche, A., Agram, J.-L., Andrea, J., Apparu, D., Bloch, D., Brom, J.-M., Chabert, E. C., Collard, C., Falke, S., Goerlach, U., Grimault, C., Haeberle, R., Bihan, A.-C. Le, Meena, M., Saha, G., Sessini, M. A., Hove, P. Van, Beauceron, S., Blancon, B., Boudoul, G., Chanon, N., Choi, J., Contardo, D., Depasse, P., Dozen, C., Mamouni, H. El, Fay, J., Gascon, S., Gouzevitch, M., Greenberg, C., Grenier, G., Ille, B., Laktineh, I. B., Lethuillier, M., Mirabito, L., Perries, S., Purohit, A., Donckt, M. 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S., Zarubin, A., Zhizhin, I., and Zhokin, A.
Published: 2024
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42. Retrospective ANalysis of multi-drug resistant Gram-nEgative bacteRia on veno-venous extracorporeal membrane oxygenation. The multicenter RANGER STUDY

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44. VC-resist glioblastoma cell state: vessel co-option as a key driver of chemoradiation resistance

Author: Pichol-Thievend, Cathy, Anezo, Oceane, Pettiwala, Aafrin M., Bourmeau, Guillaume, Montagne, Remi, Lyne, Anne-Marie, Guichet, Pierre-Olivier, Deshors, Pauline, Ballestín, Alberto, Blanchard, Benjamin, Reveilles, Juliette, Ravi, Vidhya M., Joseph, Kevin, Heiland, Dieter H., Julien, Boris, Leboucher, Sophie, Besse, Laetitia, Legoix, Patricia, Dingli, Florent, Liva, Stephane, Loew, Damarys, Giani, Elisa, Ribecco, Valentino, Furumaya, Charita, Marcos-Kovandzic, Laura, Masliantsev, Konstantin, Daubon, Thomas, Wang, Lin, Diaz, Aaron A., Schnell, Oliver, Beck, Jürgen, Servant, Nicolas, Karayan-Tapon, Lucie, Cavalli, Florence M. G., and Seano, Giorgio
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45. Software Performance of the ATLAS Track Reconstruction for LHC Run 3

Author: Aad, G., Abbott, B., Abeling, K., Abicht, N. J., Abidi, S. H., Aboulhorma, A., Abramowicz, H., Abreu, H., Abulaiti, Y., Acharya, B. S., Bourdarios, C. Adam, Adamczyk, L., Adamek, L., Addepalli, S. V., Addison, M. J., Adelman, J., Adiguzel, A., Adye, T., Affolder, A. A., Afik, Y., Agaras, M. N., Agarwala, J., Aggarwal, A., Agheorghiesei, C., Ahmad, A., Ahmadov, F., Ahmed, W. S., Ahuja, S., Ai, X., Aielli, G., Aikot, A., Tamlihat, M. Ait, Aitbenchikh, B., Aizenberg, I., Akbiyik, M., Åkesson, T. P. A., Akimov, A. V., Akiyama, D., Akolkar, N. N., Khoury, K. Al, Alberghi, G. L., Albert, J., Albicocco, P., Albouy, G. L., Alderweireldt, S., Aleksa, M., Aleksandrov, I. N., Alexa, C., Alexopoulos, T., Alfonsi, F., Algren, M., Alhroob, M., Ali, B., Ali, H. M. J., Ali, S., Alibocus, S. W., Aliev, M., Alimonti, G., Alkakhi, W., Allaire, C., Allbrooke, B. M. M., Allen, J. F., Flores, C. A. Allendes, Allport, P. P., Aloisio, A., Alonso, F., Alpigiani, C., Estevez, M. Alvarez, Fernandez, A. 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S., Young, C., Yu, C., Yu, Y., Yuan, M., Yuan, R., Yue, L., Zaazoua, M., Zabinski, B., Zaid, E., Zakareishvili, T., Zakharchuk, N., Zambito, S., Saa, J. A. Zamora, Zang, J., Zanzi, D., Zaplatilek, O., Zeitnitz, C., Zeng, H., Zeng, J. C., Zenger, Jr, D. T., Zenin, O., Ženiš, T., Zenz, S., Zerradi, S., Zerwas, D., Zhai, M., Zhang, B., Zhang, D. F., Zhang, J., Zhang, J., Zhang, K., Zhang, L., Zhang, P., Zhang, R., Zhang, S., Zhang, T., Zhang, X., Zhang, X., Zhang, Y., Zhang, Y., Zhang, Y., Zhang, Z., Zhang, Z., Zhao, H., Zhao, P., Zhao, T., Zhao, Y., Zhao, Z., Zhemchugov, A., Zheng, J., Zheng, K., Zheng, X., Zheng, Z., Zhong, D., Zhou, B., Zhou, H., Zhou, N., Zhou, Y., Zhu, C. G., Zhu, J., Zhu, Y., Zhu, Y., Zhuang, X., Zhukov, K., Zhulanov, V., Zimine, N. I., Zinsser, J., Ziolkowski, M., Živković, L., Zoccoli, A., Zoch, K., Zorbas, T. G., Zormpa, O., Zou, W., and Zwalinski, L.
Published: 2024
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Author: Raimondi Cominesi, Davide, Forcione, Mario, Pozzi, Matteo, Giani, Marco, Foti, Giuseppe, Rezoagli, Emanuele, and Cipulli, Francesco
Published: 2024
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Author: Bortolani, Arianna, Fantin, Francesco, Giani, Anna, Zivelonghi, Alessandra, Pernice, Bruno, Bortolazzi, Elena, Urbani, Silvia, Zoico, Elena, Micciolo, Rocco, and Zamboni, Mauro
Published: 2024
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48. Involvement of the ipsilateral-to-the-pain anterior–superior hypothalamic subunit in chronic cluster headache

Author: Ferraro, Stefania, Nigri, Anna, Bruzzone, Maria Grazia, Medina Carrion, Jean Paul, Fedeli, Davide, Demichelis, Greta, Chiapparini, Luisa, Ciullo, Giuseppe, Gonzalez, Ariosky Areces, Proietti Cecchini, Alberto, Giani, Luca, Becker, Benjamin, and Leone, Massimo
Published: 2024
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49. Seawater physics and chemistry along the Med-SHIP transects in the Mediterranean Sea in 2016

Author: Schroeder, Katrin, Kovačević, Vedrana, Civitarese, Giuseppe, Velaoras, Dimitris, Álvarez, Marta, Tanhua, Toste, Jullion, Loïc, Coppola, Laurent, Bensi, Manuel, Ursella, Laura, Santinelli, Chiara, Giani, Michele, Chiggiato, Jacopo, Aly-Eldeen, Mohamed, Assimakopoulou, Georgia, Bachi, Giancarlo, Bogner, Boie, Borghini, Mireno, Cardin, Vanessa, Cornec, Marin, Giannakourou, Antonia, Giannoudi, Louisa, Gogou, Alexandra, Golbol, Melek, Hazan, Or, Karthäuser, Clarissa, Kralj, Martina, Krasakopoulou, Evangelia, Matić, Frano, Mihanović, Hrvoje, Muslim, Stipe, Papadopoulos, Vassilis P., Parinos, Constantine, Paulitschke, Anne, Pavlidou, Alexandra, Pitta, Elli, Protopapa, Maria, Rahav, Eyal, Raveh, Ofrat, Renieris, Panagiotis, Reyes-Suarez, Nydia C., Rousselaki, Eleni, Silverman, Jacop, Souvermezoglou, Ekaterini, Urbini, Lidia, Zeri, Christina, and Zervoudaki, Soultana
Published: 2024
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50. Observation of tt¯sNN production in the lepton+jets and dilepton channels in p+Pb collisions at tt¯sNN = 8.16 TeV with the ATLAS detector

Author: Aad, G., Aakvaag, E., Abbott, B., Abdelhameed, S., Abeling, K., Abicht, N. J., Abidi, S. H., Aboelela, M., Aboulhorma, A., Abramowicz, H., Abreu, H., Abulaiti, Y., Acharya, B. S., Ackermann, A., Adam Bourdarios, C., Adamczyk, L., Addepalli, S. V., Addison, M. J., Adelman, J., Adiguzel, A., Adye, T., Affolder, A. A., Afik, Y., Agaras, M. N., Agarwala, J., Aggarwal, A., Agheorghiesei, C., Ahmad, A., Ahmadov, F., Ahmed, W. S., Ahuja, S., Ai, X., Aielli, G., Aikot, A., Ait Tamlihat, M., Aitbenchikh, B., Akbiyik, M., Åkesson, T. P. A., Akimov, A. V., Akiyama, D., Akolkar, N. N., Aktas, S., Al Khoury, K., Alberghi, G. L., Albert, J., Albicocco, P., Albouy, G. L., Alderweireldt, S., Alegria, Z. L., Aleksa, M., Aleksandrov, I. N., Alexa, C., Alexopoulos, T., Alfonsi, F., Algren, M., Alhroob, M., Ali, B., Ali, H. M. J., Ali, S., Alibocus, S. W., Aliev, M., Alimonti, G., Alkakhi, W., Allaire, C., Allbrooke, B. M. M., Allen, J. F., Allendes Flores, C. A., Allport, P. P., Aloisio, A., Alonso, F., Alpigiani, C., Alsolami, Z. M. K., Alvarez Estevez, M., Alvarez Fernandez, A., Alves Cardoso, M., Alviggi, M. G., Aly, M., Amaral Coutinho, Y., Ambler, A., Amelung, C., Amerl, M., Ames, C. G., Amidei, D., Amirie, K. J., Amor Dos Santos, S. P., Amos, K. R., An, S., Ananiev, V., Anastopoulos, C., Andeen, T., Anders, J. K., Andrean, S. Y., Andreazza, A., Angelidakis, S., Angerami, A., Anisenkov, A. V., Annovi, A., Antel, C., Antipov, E., Antonelli, M., Anulli, F., Aoki, M., Aoki, T., Aparo, M. A., Aperio Bella, L., Appelt, C., Apyan, A., Arbiol Val, S. J., Arcangeletti, C., Arce, A. T. H., Arena, E., Arguin, J-F., Argyropoulos, S., Arling, J.-H., Arnaez, O., Arnold, H., Artoni, G., Asada, H., Asai, K., Asai, S., Asbah, N. A., Ashby Pickering, R. A., Assamagan, K., Astalos, R., Astrand, K. S. V., Atashi, S., Atkin, R. J., Atkinson, M., Atmani, H., Atmasiddha, P. A., Augsten, K., Auricchio, S., Auriol, A. D., Austrup, V. A., Avolio, G., Axiotis, K., Azuelos, G., Babal, D., Bachacou, H., Bachas, K., Bachiu, A., Backman, F., Badea, A., Baer, T. M., Bagnaia, P., Bahmani, M., Bahner, D., Bai, K., Baines, J. T., Baines, L., Baker, O. K., Bakos, E., Bakshi Gupta, D., Balakrishnan, V., Balasubramanian, R., Baldin, E. M., Balek, P., Ballabene, E., Balli, F., Baltes, L. M., Balunas, W. K., Balz, J., Bamwidhi, I., Banas, E., Bandieramonte, M., Bandyopadhyay, A., Bansal, S., Barak, L., Barakat, M., Barberio, E. L., Barberis, D., Barbero, M., Barel, M. Z., Barends, K. N., Barillari, T., Barisits, M-S., Barklow, T., Baron, P., Baron Moreno, D. A., Baroncelli, A., Barone, G., Barr, A. J., Barr, J. D., Barreiro, F., Barreiro Guimarães da Costa, J., Barron, U., Barros Teixeira, M. G., Barsov, S., Bartels, F., Bartoldus, R., Barton, A. E., Bartos, P., Basan, A., Baselga, M., Bassalat, A., Basso, M. J., Bate, R., Bates, R. 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Published: 2024
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