104 results on '"GERMINARIO C."'
Search Results
2. May a comprehensive mineralogical study of a jackstone calculus and some other human bladder stones unveil health and environmental implications?
- Author
-
Mercurio, M., Izzo, F., Gatta, Giacomo Diego, Salzano, L., Lotrecchiano, G., Saldutto, P., Germinario, C., Grifa, C., Varricchio, E., Carafa, A., Di Meo, Maria Chiara, and Langella, A.
- Published
- 2022
- Full Text
- View/download PDF
3. Identifying Original and Restoration Materials through Spectroscopic Analyses on Saturnino Gatti Mural Paintings: How Far a Noninvasive Approach Can Go
- Author
-
Bonizzoni, L, Caglio, S, Galli, A, Germinario, C, Izzo, F, Magrini, D, Bonizzoni, Letizia, Caglio, Simone, Galli, Anna, Germinario, Chiara, Izzo, Francesco, Magrini, Donata, Bonizzoni, L, Caglio, S, Galli, A, Germinario, C, Izzo, F, Magrini, D, Bonizzoni, Letizia, Caglio, Simone, Galli, Anna, Germinario, Chiara, Izzo, Francesco, and Magrini, Donata
- Abstract
This paper presents the results obtained for the mural paintings (XV century CE) in the church of San Panfilo in Villagrande di Tornimparte (AQ, Italy) by means of noninvasive spectroscopic techniques; this research is a part of the project on the Saturnino Gatti pictorial cycle, promoted and coordinated by the AIAr (the Italian Archaeometry Association). Digital optical microscopy (OM), X-ray fluorescence spectroscopy (XRF), fiber optics reflectance spectroscopy in the UV–Vis–NIR range (FORS), Fourier transform infrared spectroscopy in the external reflection mode (ER-FTIR), and Raman spectroscopy were performed on the points selected based on the image analysis results and the few available records on previous intervention, with the aim of characterizing both the original and restoration organic and inorganic materials. The synergic application of complementary techniques allowed us to obtain a complete picture of the palette and the main alteration products and organic substances (of rather ubiquitous lipid materials and less widespread resin and proteinaceous materials in specific points). The identification of modern compounds permitted the individuation of restoration areas; this was confirmed by the comparison with multiband imaging results, as in the case of specific green and blue pigments, strictly related to the presence of high signals of zinc. This analytical protocol left only very few ambiguities and allowed to minimizing the number of samples taken to clarifying, by sample laboratory analyses, the few doubts still open.
- Published
- 2023
4. Monitoring the process of measles elimination by serosurveillance data: The Apulian 2012 study
- Author
-
Tafuri, S., Gallone, M.S., Gallone, M.F., Pappagallo, M.T., Larocca, A., and Germinario, C.
- Published
- 2016
- Full Text
- View/download PDF
5. A seroprevalence survey on varicella among adults in the vaccination era in Apulia (Italy)
- Author
-
Tafuri, S., Gallone, M.S., Cappelli, M.G., Gallone, M.F., Larocca, A.M.V., and Germinario, C.
- Published
- 2014
- Full Text
- View/download PDF
6. May a comprehensive mineralogical study of a jackstone calculus and some other human bladder stones unveil health and environmental implications?
- Author
-
Mercurio, M., primary, Izzo, F., additional, Gatta, Giacomo Diego, additional, Salzano, L., additional, Lotrecchiano, G., additional, Saldutto, P., additional, Germinario, C., additional, Grifa, C., additional, Varricchio, E., additional, Carafa, A., additional, Di Meo, Maria Chiara, additional, and Langella, A., additional
- Published
- 2021
- Full Text
- View/download PDF
7. Impatto dell’emergenza COVID-19 sui volumi di attività della chirurgia protesica ortopedica in sette Regioni italiane. Versione del 17 marzo 2021
- Author
-
Torre, M, Urakcheeva, I, Ciminello, E, Aprato, A, Favella, L, Ferro, S, Ercolanoni, M, Leoni, O, Picus, R, Armaroli, C, Molinari, M, Bachini, L, Gemmi, F, Germinario, C, Moretti, B, Allotta, A, Boniforti, F, Ceccarelli, S, and Laricchiuta, P.
- Subjects
chirurgia protesica ,COVID-19 ,joint arthroplasties ,protesi d'anca - Published
- 2021
8. Mortar radiocarbon dating: Cryo2sonic sample preparation procedure. method and applications
- Author
-
Ricci P., Germinario C., Lubritto C., Ricci, P., Germinario, C., and Lubritto, C.
- Subjects
Mortar ,Radiocarbon dating ,Cryo2Sonic method ,Characterization tecnique ,Chronology - Abstract
The absolute chronology of archaeological contexts is mainly based on the radiocarbon dating of organic materials. This analytical approach often provides misleading results when the goal is to find a surprising relationship between organic matter and archaeological structures. Thus, discovering new radiocarbon dating methodologies on mortar samples, represents one of the main “open problems” involving the entire radiocarbon community. Mortars are heterogeneous building materials composed of a mixture of inorganic and/or organic binders, and inert with sandy dimensions. Indeed, the lime binder in mortar can be used to date archaeological structures, since the carbon dioxide absorbed during the setting of the mortar probably reflects the14C content existing in the atmosphere at that time. The main sources of carbon dioxide, that potentially contribute to a biasing in the final measure, are: the residues of primary carbonates (calcination relics) originating from the incomplete limestone combustion during the process of producing lime; aggregates containing carbonates used as inert materials during the production phases of the mortar; and newly formed carbonates precipitated after the interaction between running water or rain. Therefore, the preparation of the samples must eliminate the contamination (aggregate, calcination relics or crystallization of new calcite) which must be separated from the carbon belonging to the original binder. The methods, now more commonly used for the preparation of mortar samples, consist of a mechanical pre-treatment or a chemical treatment. This paper illustrates the so-called Cryo2Sonic procedure, and how it has been improved over time (previously it was “CryoSonic”), and developed with the use of other complementary techniques. Moreover, various case studies will be presented in which this radiocarbon dating protocol has been applied to mortars of different structures belonging to different phases and historical contexts. The results have not always been good, as there are many sources of contamination from the different origins of CO2. Our goal is to eliminate contamination as much as possible, or at least try to limit the effect of CO2 contamination.
- Published
- 2019
9. Results of diagnostic campaign promoted by AIAr in the deposits of the Archaeological Museum of Paestum
- Author
-
Oddo, M, Ricci, P, Angelici, D, Fantino, F, Sibilia, E, Alberghina, M, Schiavone, S, Grifa, C, Mercurio, M, Germinario, C, Izzo, F, Langella, A, Massa, E, Bracci, S, Magrini, D, Costa, R, Pelagotti, A, Zuchtriegel, G, Lubritto, C, Oddo, M. E, Ricci, P., Angelici, D., Fantino, F., Sibilia, E., Alberghina, M. F, Schiavone, S., Grifa, C., Mercurio, M., Germinario, C., Izzo, F., Langella, A., Massa, E., Bracci, S., Magrini, D., Costa, R., Pelagotti, A., Zuchtriegel, G., Lubritto, C., Oddo, M, Ricci, P, Angelici, D, Fantino, F, Sibilia, E, Alberghina, M, Schiavone, S, Grifa, C, Mercurio, M, Germinario, C, Izzo, F, Langella, A, Massa, E, Bracci, S, Magrini, D, Costa, R, Pelagotti, A, Zuchtriegel, G, Lubritto, C, Oddo, M. E, Ricci, P., Angelici, D., Fantino, F., Sibilia, E., Alberghina, M. F, Schiavone, S., Grifa, C., Mercurio, M., Germinario, C., Izzo, F., Langella, A., Massa, E., Bracci, S., Magrini, D., Costa, R., Pelagotti, A., Zuchtriegel, G., and Lubritto, C.
- Abstract
Thirty artefacts from the Archaeological Park of Paestum were investigated by means of scientific techniques on the occasion of the 2016 exhibition 'Possessione. Trafugamenti e falsi di antichita a Paestum'. The multi-analytic diagnostic campaign was aimed at identifying forgeries. Results provided a deeper understanding of both ancient technology and contemporary forgery techniques.
- Published
- 2018
10. Non-invasive characterization of the pigment’s palette used on the painted tomb slabs at Paestum archaeological site
- Author
-
Alberghina, M. F., primary, Germinario, C., additional, Bartolozzi, G., additional, Bracci, S., additional, Grifa, C., additional, Izzo, F., additional, La Russa, M.F., additional, Magrini, D., additional, Massa, E., additional, Mercurio, M., additional, Mollica Nardo, V., additional, Oddo, M.E., additional, Pagnotta, S. M., additional, Pelagotti, A., additional, Ponterio, R. C., additional, Ricci, P., additional, Rovella, N., additional, Ruffolo, S. A., additional, Schiavone, S., additional, Spagnuolo, A., additional, Vetromile, C., additional, Zuchtriegel, G., additional, and Lubritto, C., additional
- Published
- 2020
- Full Text
- View/download PDF
11. Characterization of ancient building lime mortars of Anhui province, China: A multi‐analytical approach
- Author
-
Wei, G., primary, Germinario, C., additional, Grifa, C., additional, and Ma, X., additional
- Published
- 2020
- Full Text
- View/download PDF
12. Raw materials for ancient ceramic productions from Campania region: provenance studies by means of Sr-Nd isotopes
- Author
-
Morra V., Arienzo I., D’Antonio M., De Bonis A., Germinario C., Grifa C., Guarino V., Langella A., Società Geologica Italiana, Morra, V., Arienzo, I., D’Antonio, M., De Bonis, A., Germinario, C., Grifa, C., Guarino, V., and Langella, A.
- Subjects
Sr-Nd isotopes, archaeological pottery, provenance - Abstract
When archaeometric studies on archaeological ceramics are performed, one of the most important questions asked by archaeologists is the provenance of pottery. This is usually performed by comparing mineropetrographic and chemical composition of ceramics with that of local raw materials (clays, temper), production indicators and appropriate reference groups. Nevertheless, the commonly-used analytical techniques (e.g. OM, SEM-EDS, XRF, ICP-MS) may not always be helpful for the determination of provenance. Indeed, processing of raw materials, such as tempering or levigation, can significantly modify their original chemical composition, sometimes leading to an ineffective identification of raw material resources. For this reason, a pioneering analytical approach has been recently applied by measuring the Sr and Nd isotopic signature. Isotope analysis has largely used in archaeological sciences to date objects and identify their provenance, making it also a useful tool for the determination of provenance of ceramic vessels (De Bonis et al., 2018 and references therein). For this study, 87Sr/86Sr and 143Nd/144Nd isotope ratios were measured on archaeological pottery from Campania and raw materials (clays and volcanic temper) exploited in antiquity for producing ceramics. The analyses were focused on samples from both the Bay of Naples and Southern Campania. The isotope signatures allowed us to better discriminate among different productions and find a strong relationship between the archaeological pottery and the geological sources of raw materials. In order to validate the method, Sr-Nd isotope ratios were also measured for the first time on experimental ceramic materials that replicate archaeological pottery (De Bonis et al., 2018). It was interesting to note that synthetic mixtures used for the ceramic replicas plot exactly on the theoretical mixing curve between the clay and volcanic temper end-members. This suggests that the artificial manipulation of raw materials (firing, levigation, tempering) induces no significant variations to the Sr-Nd isotope fingerprint, which strictly depends on the geochemical affinity of the raw materials. Thus, isotopic analysis can be considered as an effective and robust method that could complement the common multi-analytical approach in order to more precisely constrain potential geological sources for ceramic materials and pottery provenance. De Bonis, A., Arienzo I., D’Antonio, M., Franciosi, L., Germinario, C., Grifa, C., Guarino, V., Langella, A. & Morra, V. (2018): Sr-Nd isotopic fingerprint as a tool for ceramic provenance: application on raw materials, ceramic replicas and ancient pottery. J. Archaeol. Sci., 94, 51-59.
- Published
- 2018
13. Interim 2017/18 influenza seasonal vaccine effectiveness: combined results from five European studies
- Author
-
Rondy, M, Kissling, E, Emborg, Hd, Gherasim, A, Pebody, R, Trebbien, R, Pozo, F, Larrauri, A, Mcmenamin, J, Valenciano, M, Kaic, B, Kurecic Filipovic, S, Visekruna-Vucina, V, Pem Novosel, I, Lovric, Z, Petrović, G, Krause, Tg, Fischer, Tk, Lina, B, Falchi, Antonella, Vilcu, Am, Souty, C, Blanchon, T, van der Werf, S, Enouf, V, Behillil, S, Valette, M, Bernard-Stoecklin, S, Lévy-Bruhl, D, Launay, O, Loulergue, P, Lenzi, N, Lesieur, Z, L'Honneur, As, Galtier, F, Agostini, C, Serrand, C, Merle, C, Foulongne, V, Vanhems, P, Lainé, F, Lagathu, G, Carrat, F, Buda, S, Preuss, U, Prahm, K, Schweiger, B, Wedde, M, Heider, A, Martin, M, Biere, B, Duerrwald, R, Domegan, L, Coughlan, L, O’Donnell, J, Joyce, M, Collins, C, Dunford, L, Martin Moran, Josè Manuel, Tuite, G, Duffy, M, Connell, J, de Gascun, C, Rizzo, C, Bella, A, Alfonsi, V, Castrucci, Mr, Puzelli, S, Pagani, E, Ghisetti, V, Pariani, E, Baldanti, F, Palù, G, D'Agaro, P, Ansaldi, F, Affanni, P, Rossolini, Gm, Camilloni, B, Bagnarelli, P, Sanguinetti, M, Atripaldi, L, Chironna, M, Serra, C, Vitale, F, Germinario, C, Orsi, A, Manini, I, Montomoli, E, Napoli, C, Orsi, Gb, Casado, I, Castilla, J, Fernandino, L, Martínez-Baz, I, Ezpeleta, G, Navascués, A, Pérez-García, A, Aguinaga, A, Ezpeleta, C, Meijer, A, van den Brink, S, van der Hoek, W, Goderski, G, Wijsman, L, Bagheri, M, Dijkstra, F, de Lange, M, Marzec, T, Overduin, P, Teirlinck, A, Wentink, E, Donker, G, Marbus, S, van Gageldonk- Lafeber, R, Schneeberger, P, van Oosterheert JJ, Schweitzer, V, Groeneveld, G, Nunes, B, RIBEIRO MACHADO, CARLOS AUGUSTO, Rodrigues, Ap, DIAZ GOMEZ, MARIA VANESSA, Kislaya, I, Guiomar, R, Pechirra, P, Cristóvão, P, Costa, I, Panarra, A, Côrte-Real, R, Poças, J, João Peres, M, García Comas, L, Marisquerena, Mei, Galán, Jc, Folgueira, D, Gonzalez Carril, F, Sancho Martínez, R, Cilla, G, García Cenoz, M, Quiñones Rubio, C, Martinez Ochoa, E, Blasco, M, Gimenez Duran, J, Vanrell, Jm, Reina, J, Castrillejo, D, Gherasim, Am, Delgado, C, Oliva, J, Casas, I, García, M, Latorre, M, Milagro Beamonte AM, Martinez Sapiñ, A, Oribe Amores, M, Aizpurúa, A, Montes, Marco, Zakikhany, K, Brytting, M, Wiman, Å, Carnahan, A, Warburton, F, Djennad, A, Ellis, J, Andrews, N, Marques, D, Cottrell, S, Reynolds, Alexander, Gunson, R, Galiano, M, Lackenby, A, Robertson, C, O’Doherty, M, Sinnathamby, M, Yonova, I, Moore, C, Sartaj, M, de Lusignan, S, Zambon, M, Moren, A, Penttinen, P., Unión Europea, EpiConcept [Paris], Statens Serum Institut [Copenhagen], Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier), Pathogénèse et contrôle des infections chroniques (PCCI), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Montpellier (UM)-Centre Hospitalier Universitaire de Montpellier (CHU Montpellier ), Rondy M., Kissling E., Emborg H.-D., Gherasim A., Pebody R., Trebbien R., Pozo F., Larrauri A., McMenamin J., Valenciano M., Kaic B., Filipovic S.K., Visekruna-Vucina V., Novosel I.P., Lovric Z., Petrovic G., Krause T.G., Fische T.K., Lina B., Falchi A., Vilcu A.-M., Souty C., Blanchon T., van der Werf S., Enouf V., Behillil S., Valette M., Bernard-Stoecklin S., Levy-Bruhl D., Launay O., Loulergue P., Lenzi N., Lesieur Z., L'Honneur A.-S., Galtier F., Agostini C., Serrand C., Merle C., Foulongne V., Vanhems P., Laine F., Lagathu G., Carrat F., Buda S., Preuss U., Prahm K., Schweiger B., Wedde M., Heider A., Martin M., Biere B., Duerrwald R., Domegan L., Coughlan L., O'Donnell J., Joyce M., Collins C., Dunford L., Moran J., Tuite G., Duffy M., Connell J., de Gascun C., Rizzo C., Bella A., Alfonsi V., Castrucci M.R., Puzelli S., Pagani E., Ghisetti V., Pariani E., Baldanti F., Palu G., D'Agaro P., Ansaldi F., Affanni P., Rossolini G.M., Camilloni B., Bagnarelli P., Sanguinetti M., Atripaldi L., Chironna M., Serra C., Vitale F., Germinario C., Orsi A., Manini I., Montomoli E., Napoli C., Orsi G.B., Casado I., Castilla J., Fernandino L., Martinez-Baz I., Ezpeleta G., Navascues A., Perez-Garcia A., Aguinaga A., Ezpeleta C., Meijer A., van den Brink S., van der Hoek W., Goderski G., Wijsman L., Bagheri M., Dijkstra F., de Lange M., Marzec T., Overduin P., Teirlinck A., Wentink E., Donker G., Marbus S., van Gageldonk-Lafeber R., Schneeberger P., van Oosterheert J.J., Schweitzer V., Groeneveld G., Nunes B., Machado A., Rodrigues A.P., Gomez V., Kislaya I., Guiomar R., Pechirra P., Cristovao P., Costa I., Panarra A., Corte-Real R., Pocas J., Peres M.J., Comas L.G., Marisquerena M.E.I., Galan J.C., Folgueira M.D., Carril F.G., Martinez R.S., Cilla G., Cenoz M.G., Rubio C.Q., Ochoa E.M., Blasco M., Duran J.G., Vanrell J.M., Reina J., Castrillejo D., Gherasim A.M., Delgado C., Oliva J., Casas I., Garcia M., Latorre M., Beamonte A.M.M., Sapina A.M., Amores M.O., Aizpurua A., Montes M., Zakikhany K., Brytting M., Wiman A., Carnahan A., Warburton F., Djennad A., Ellis J., Andrews N., Marques D., Cottrell S., Reynolds A., Gunson R., Galiano M., Lackenby A., Robertson C., O'Doherty M., Sinnathamby M., Yonova I., Moore C., Sartaj M., de Lusignan S., Zambon M., Moren A., Penttinen P., Génétique Moléculaire des Virus à ARN - Molecular Genetics of RNA Viruses (GMV-ARN (UMR_3569 / U-Pasteur_2)), Institut Pasteur [Paris] (IP)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS), Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Montpellier (UM), Marc, Rondy, Esther, Kissling, Hanne-Dorthe, Emborg, Alin, Gherasim, Richard, Pebody, Ramona, Trebbien, Francisco, Pozo, Amparo, Larrauri, Jim, Mcmenamin, Marta, Valenciano, D'Agaro, Pierlanfranco, De Lusignan, S, and Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre Hospitalier Universitaire de Montpellier (CHU Montpellier )-Université de Montpellier (UM)
- Subjects
0301 basic medicine ,Male ,Pediatrics ,Epidemiology ,viruses ,Influenza B viru ,influenza ,influenza vaccine effectiveness ,influenza vaccination ,case control study ,multicentre study ,Europe ,Europe, case control study, influenza, influenza vaccination, influenza vaccine effectiveness, multicentre study ,0302 clinical medicine ,Influenza A Virus, H1N1 Subtype ,[SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseases ,Interim ,Pandemic ,Influenza A Virus ,030212 general & internal medicine ,QA ,Influenza vaccine effectiveness ,Child ,media_common ,Vaccine Effectiveness ,Vaccination ,virus diseases ,Middle Aged ,3. Good health ,Treatment Outcome ,Influenza Vaccines ,Child, Preschool ,H3N2 Subtype ,Female ,Seasons ,Influenza Vaccine ,Rapid Communication ,Human ,Adult ,RM ,medicine.medical_specialty ,Adolescent ,Influenza vaccine ,030106 microbiology ,Case control study ,Multicentre study ,European studies ,Settore MED/07 - MICROBIOLOGIA E MICROBIOLOGIA CLINICA ,03 medical and health sciences ,Virology ,Influenza, Human ,medicine ,media_common.cataloged_instance ,Humans ,H1N1 Subtype ,Vacina Antigripal ,European Union ,European union ,Preschool ,Pandemics ,Aged ,Influenza A Virus, H3N2 Subtype ,Cuidados de Saúde ,Public Health, Environmental and Occupational Health ,Infant, Newborn ,Infant ,Influenza a ,influenza vaccine effectivene ,Newborn ,Influenza ,respiratory tract diseases ,Influenza vaccination ,Influenza B virus ,[SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie ,Determinantes da Saúde e da Doença ,[SDV.IMM.VAC]Life Sciences [q-bio]/Immunology/Vaccinology - Abstract
Between September 2017 and February 2018, influenza A(H1N1)pdm09, A(H3N2) and B viruses (mainly B/Yamagata, not included in 2017/18 trivalent vaccines) co-circulated in Europe. Interim results from five European studies indicate that, in all age groups, 2017/18 influenza vaccine effectiveness was 25 to 52% against any influenza, 55 to 68% against influenza A(H1N1)pdm09, -42 to 7% against influenza A(H3N2) and 36 to 54% against influenza B. 2017/18 influenza vaccine should be promoted where influenza still circulates. Funding: The five studies have received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement No 634446 to conduct the study in individuals aged 65 years or more. ECDC has contributed to fund some study sites of the EU-PC study under the Framework contract No ECDC/2014/026 for the individuals aged less than 65 years. All study teams are very grateful to all patients, general practitioners, paediatricians, hospital teams, laboratory teams, regional epidemiologists who have contributed to the studies. We acknowledge the authors, originating and submitting laboratories of the sequences from GISAID’s EpiFlu Database used for this study. All submitters of data may be contacted directly via the GISAID website www.gisaid.org Sí
- Published
- 2018
14. [The health determinants in young children: testing a new surveillance system in Italy]
- Author
-
Pizzi, E., Spinelli, A., Battilomo, S., Azzarito, C., Balducci, M. T., Bettinelli, M. E., Campostrini, S., Germinario, C., Mazzarella, Guido, Mignuoli, A. D., Morbidoni, M., Porchia, Stefania, Simeoni, Loris, Speri, Laura, Bucciarelli, M., Buoncristiano, M., Lauria, L., Nardone, P., Privitera, M. G., Brancati, G., Raffa, R., Napoli, T., Cimminelli, L., Vitelli, A., Panico, M., Ragone, G., D'Anna, A., Nardacci, A., Benedetti, E., Ambrogiani, E., Guidi, A., Cimini, D., Marcolini, P., Pasqualini, F., Rossini, Roberta, Zappi, W., Lacaita, G., Valentini, M., Pedote, P. D., Pesare, A., Caputi, G., Gottardello, L., and Campi, Davide
- Subjects
Vaccination centres ,Childhood ,Health determinants ,Surveillance system ,Italy ,Child, Preschool ,Population Surveillance ,Child Health ,Humans ,Infant ,Settore SECS-S/05 - Statistica Sociale - Abstract
In recent years, the scientific community has stressed the need to invest in the first 1,000 days of life - the time spanning between conception and the 2nd birthday - because it is during this period that the foundations of health are laid and whose effects will be present throughout the life and may influence the next generation. Taking this into account, in 2013 the National Centre for Disease Prevention and Control (CCM) of the Italian Ministry of Health promoted and financed a project to test a surveillance system of the main determinants of health concerning the child between the conception period and the 2nd years of life which are included in the National Programme "GenitoriPiù": folic acid before and during pregnancy, abstention from tobacco and alcohol during pregnancy and lactation, breastfeeding, infant sleep position, vaccination attitude, and early reading. The Project, started in January 2014 and ended in August 2016, has piloted the design, testing, and evaluation of the surveillance system with the view to national extension and the repeatability over time. The surveillance system has been designed to collect data through a questionnaire compiled by mothers in vaccination centres, in order to produce indicators which will enable territorial and intertemporal comparisons to be made. The project has shown the feasibility of this system, identifying favourable conditions and possible difficulties, and its ability to collect important information on children's health.
- Published
- 2019
15. Moderate influenza vaccine effectiveness against A(H1N1)pdm09 virus, and low effectiveness against A(H3N2) subtype, 2018/19 season in Italy
- Author
-
Bellino, S., Bella, A., Puzelli, S., Di Martino, A., Facchini, M., Punzo, O., Pezzotti, P., Castrucci, M.R., Di Mario, G., Calzoletti, L., Fabiani, C., Chironna, M., Germinario, C., Tramuto, F., Di Carlo, V., Affanni, P., Grazia Pascucci, M., D'Agaro, P., Gallo, T., Pagani, E., Natter, B., Camilloni, B., Tosti, A., Pariani, E., Senatore, S., Serra, C., Rita Tanchis, P., Ghisetti, V., Tiberti, D., Romano, L., Volpe, E., Giannecchini, S., and Bellino S, Bella A, Puzelli S, Di Martino A, Facchini M, Punzo O, Pezzotti P, Castrucci MR, Tramuto F, The InfluNet Study Group.
- Subjects
Male ,test-negative case-control study ,0301 basic medicine ,Prevalence ,Influenza vaccine effectiveness, test-negative case-control study, national influenza surveillance network, Italy ,Settore MED/42 - Igiene Generale E Applicata ,Influenza A Virus, H1N1 Subtype ,0302 clinical medicine ,Drug Discovery ,Epidemiology ,030212 general & internal medicine ,Child ,Influenza vaccine effectiveness ,Aged, 80 and over ,national influenza surveillance network ,Age Factors ,virus diseases ,Middle Aged ,3. Good health ,Vaccination ,Treatment Outcome ,Italy ,Influenza Vaccines ,Child, Preschool ,Molecular Medicine ,Female ,Adult ,medicine.medical_specialty ,Adolescent ,Influenza vaccine ,Immunology ,Context (language use) ,Virus ,Young Adult ,03 medical and health sciences ,Internal medicine ,Influenza, Human ,medicine ,Animals ,Humans ,Aged ,Pharmacology ,business.industry ,Influenza A Virus, H3N2 Subtype ,Case-control study ,Infant ,030104 developmental biology ,Immunization ,Case-Control Studies ,business - Abstract
Background: Influenza vaccines are updated every year to match the vaccine strains with currently circulating viruses; consequently influenza vaccine effectiveness (IVE) has to be assessed annually.Research design and methods: A test-negative case-control study was conducted within the context of the Italian sentinel influenza surveillance network to estimate IVE by age group, virus subtype, and vaccine brand in medically attended laboratory-confirmed influenza.Results: In Italy, the 2018/19 influenza season was characterized by the co-circulation of influenza A(H1N1)pdm09 and A(H3N2) viruses. The adjusted IVE estimate in preventing influenza was moderate (44.8%, 95% CI: 18.8 to 62.5) against A(H1N1)pdm09, whereas there was no evidence of effectiveness (1.8%, 95% CI: -37.8 to 30.1) in persons affected by A(H3N2). IVE against A(H1N1)pdm09 decreased with age ranging from 65.7% to 13.1% among children/adolescents and elderly, respectively; moreover results suggest that Vaxigrip Tetra® was more effective against A(H1N1)pdm09 compared to Fluarix Tetra® [62.5% (95% CI: 34.3 to 78.6) vs 24.5% (95% CI: -40.6 to 59.6)]. Low effectiveness (35.2%, 95% CI: -50.8 to 72.1) against A(H3N2) was detected only in the elderly immunized with Fluad®.Conclusions: Findings suggest that influenza vaccines were low to moderately effective, probably due to a mismatch between circulating and vaccine strains.
- Published
- 2019
- Full Text
- View/download PDF
16. Metodo di ricerca per individuare la brevettabilità di anticorpi monoclonali per uso terapeutico
- Author
-
Bertoli, S., Germinario, C., RAMPINELLI, PATRIZIA, CINI, MAURIZIO, Bertoli, S., Germinario, C., Rampinelli, P., and Cini, M.
- Subjects
anticorpi monoclonali, brevettabilità - Published
- 2017
17. Raw materials for archaeological pottery: a multianalytical approach
- Author
-
De Bonis, A., Arienzo, I., Germinario, C., Aiello, G., D'ANTONIO, MASSIMO, GRIFA, Celestino, GUARINO, VINCENZA, LANGELLA, ALESSIO, MERCURIO, MARIANO, AMORE, FILOMENA ORNELLA, BARRA, DIANA, MORRA, VINCENZO, De Bonis, A., Arienzo, I., D'Antonio, Massimo, Germinario, C., Grifa, Celestino, Guarino, Vincenza, Langella, Alessio, Mercurio, Mariano, Amore, FILOMENA ORNELLA, Barra, Diana, Aiello, G., and Morra, Vincenzo
- Published
- 2016
18. Multi-analytical characterization and provenance identification of protohistoric metallic artefacts from Picentia-Pontecagnano and the Sarno valley sites, Campania, Italy
- Author
-
Balassone, G, Mercurio, M, Germinario, C, Grifa, C, Villa, I, Di Maio, G, Scala, S, de’ Gennaro, R, Petti, C, Del Re, M, Langella, A, Balassone, Giuseppina, Mercurio, Mariano, Germinario, Chiara, Grifa, Celestino, Villa, Igor Maria, Di Maio, Giovanni, Scala, Serenella, de’ Gennaro, Roberto, Petti, Carmela, Del Re, Maria Carmela, Langella, Alessio, Balassone, G, Mercurio, M, Germinario, C, Grifa, C, Villa, I, Di Maio, G, Scala, S, de’ Gennaro, R, Petti, C, Del Re, M, Langella, A, Balassone, Giuseppina, Mercurio, Mariano, Germinario, Chiara, Grifa, Celestino, Villa, Igor Maria, Di Maio, Giovanni, Scala, Serenella, de’ Gennaro, Roberto, Petti, Carmela, Del Re, Maria Carmela, and Langella, Alessio
- Abstract
Protohistoric metal objects coming from the archaeological sites of Pontecagnano (Salerno, Italy) and Striano (Naples, Italy), preserved in the Pontecagnano National Archaeological Museum and the Paleontological Museum of Naples University “Federico II” have been studied by means of an archaeometric approach. A multi-analytical procedure including X-ray powder diffraction (XRPD), scanning electron microscopy and energy dispersive X-ray spectroscopy (SEM-EDS), micro X-ray fluorescence (µ-XRF) and lead isotope ratio mass spectrometry (LIRMS), was used to characterize these objects thus providing hypotheses on the possible provenance of metallic raw materials. The investigated samples are represented by lead, silver, copper and tin bronze-based objects. Corrosion processes affecting the bronze objects were recognized as well as crusts and patinae at different stages of evolution. LIRMS analyses suggested that most of Pontecagnano artifacts were manufactured with metals from southern Tuscany, where important metal reserves were located. On the other hand, due to the limited number of samples, the provenance of the Striano objects cannot be unambiguously identified although data so far available suggest a Sardinian source.
- Published
- 2018
19. Interim 2017/18 influenza seasonal vaccine effectiveness: Combined results from five European studies
- Author
-
Rondy, M., Kissling, E., Emborg, H. -D., Gherasim, A., Pebody, R., Trebbien, R., Pozo, F., Larrauri, A., Mcmenamin, J., Valenciano, M., Kaic, B., Filipovic, S. K., Visekruna-Vucina, V., Novosel, I. P., Lovric, Z., Petrovic, G., Krause, T. G., Fische, T. K., Lina, B., Falchi, A., Vilcu, A. -M., Souty, C., Blanchon, T., van der Werf, S., Enouf, V., Behillil, S., Valette, M., Bernard-Stoecklin, S., Levy-Bruhl, D., Launay, O., Loulergue, P., Lenzi, N., Lesieur, Z., L'Honneur, A. -S., Galtier, F., Agostini, C., Serrand, C., Merle, C., Foulongne, V., Vanhems, P., Laine, F., Lagathu, G., Carrat, F., Buda, S., Preuss, U., Prahm, K., Schweiger, B., Wedde, M., Heider, A., Martin, M., Biere, B., Duerrwald, R., Domegan, L., Coughlan, L., O'Donnell, J., Joyce, M., Collins, C., Dunford, L., Moran, J., Tuite, G., Duffy, M., Connell, J., de Gascun, C., Rizzo, C., Bella, A., Alfonsi, V., Castrucci, M. R., Puzelli, S., Pagani, E., Ghisetti, V., Pariani, E., Baldanti, F., Palu, G., D'Agaro, P., Ansaldi, F., Affanni, P., Rossolini, G. M., Camilloni, B., Bagnarelli, P., Sanguinetti, Maurizio, Atripaldi, L., Chironna, M., Serra, C., Vitale, F., Germinario, C., Orsi, A., Manini, I., Montomoli, E., Napoli, C., Orsi, G. B., Casado, I., Castilla, J., Fernandino, L., Martinez-Baz, I., Ezpeleta, G., Navascues, A., Perez-Garcia, A., Aguinaga, A., Ezpeleta, C., Meijer, A., van den Brink, S., van der Hoek, W., Goderski, G., Wijsman, L., Bagheri, M., Dijkstra, F., de Lange, M., Marzec, T., Overduin, P., Teirlinck, A., Wentink, E., Donker, G., Marbus, S., van Gageldonk-Lafeber, R., Schneeberger, P., van Oosterheert, J. J., Schweitzer, V., Groeneveld, G., Nunes, B., Machado, A., Rodrigues, A. P., Gomez, V., Kislaya, I., Guiomar, R., Pechirra, P., Cristovao, P., Costa, I., Panarra, A., Corte-Real, R., Pocas, J., Peres, M. J., Comas, L. G., Marisquerena, M. E. I., Galan, J. C., Folgueira, M. D., Carril, F. G., Martinez, R. S., Cilla, G., Cenoz, M. G., Rubio, C. Q., Ochoa, E. M., Blasco, M., Duran, J. G., Vanrell, J. M., Reina, J., Castrillejo, D., Gherasim, A. M., Delgado, C., Oliva, J., Casas, I., Garcia, M., Latorre, M., Beamonte, A. M. M., Sapina, A. M., Amores, M. O., Aizpurua, A., Montes, M., Zakikhany, K., Brytting, M., Wiman, A., Carnahan, A., Warburton, F., Djennad, A., Ellis, J., Andrews, N., Marques, D., Cottrell, S., Reynolds, A., Gunson, R., Galiano, M., Lackenby, A., Robertson, C., O'Doherty, M., Sinnathamby, M., Yonova, I., Moore, C., Sartaj, M., de Lusignan, S., Zambon, M., Moren, A., Penttinen, P., Sanguinetti M. (ORCID:0000-0002-9780-7059), Rondy, M., Kissling, E., Emborg, H. -D., Gherasim, A., Pebody, R., Trebbien, R., Pozo, F., Larrauri, A., Mcmenamin, J., Valenciano, M., Kaic, B., Filipovic, S. K., Visekruna-Vucina, V., Novosel, I. P., Lovric, Z., Petrovic, G., Krause, T. G., Fische, T. K., Lina, B., Falchi, A., Vilcu, A. -M., Souty, C., Blanchon, T., van der Werf, S., Enouf, V., Behillil, S., Valette, M., Bernard-Stoecklin, S., Levy-Bruhl, D., Launay, O., Loulergue, P., Lenzi, N., Lesieur, Z., L'Honneur, A. -S., Galtier, F., Agostini, C., Serrand, C., Merle, C., Foulongne, V., Vanhems, P., Laine, F., Lagathu, G., Carrat, F., Buda, S., Preuss, U., Prahm, K., Schweiger, B., Wedde, M., Heider, A., Martin, M., Biere, B., Duerrwald, R., Domegan, L., Coughlan, L., O'Donnell, J., Joyce, M., Collins, C., Dunford, L., Moran, J., Tuite, G., Duffy, M., Connell, J., de Gascun, C., Rizzo, C., Bella, A., Alfonsi, V., Castrucci, M. R., Puzelli, S., Pagani, E., Ghisetti, V., Pariani, E., Baldanti, F., Palu, G., D'Agaro, P., Ansaldi, F., Affanni, P., Rossolini, G. M., Camilloni, B., Bagnarelli, P., Sanguinetti, Maurizio, Atripaldi, L., Chironna, M., Serra, C., Vitale, F., Germinario, C., Orsi, A., Manini, I., Montomoli, E., Napoli, C., Orsi, G. B., Casado, I., Castilla, J., Fernandino, L., Martinez-Baz, I., Ezpeleta, G., Navascues, A., Perez-Garcia, A., Aguinaga, A., Ezpeleta, C., Meijer, A., van den Brink, S., van der Hoek, W., Goderski, G., Wijsman, L., Bagheri, M., Dijkstra, F., de Lange, M., Marzec, T., Overduin, P., Teirlinck, A., Wentink, E., Donker, G., Marbus, S., van Gageldonk-Lafeber, R., Schneeberger, P., van Oosterheert, J. J., Schweitzer, V., Groeneveld, G., Nunes, B., Machado, A., Rodrigues, A. P., Gomez, V., Kislaya, I., Guiomar, R., Pechirra, P., Cristovao, P., Costa, I., Panarra, A., Corte-Real, R., Pocas, J., Peres, M. J., Comas, L. G., Marisquerena, M. E. I., Galan, J. C., Folgueira, M. D., Carril, F. G., Martinez, R. S., Cilla, G., Cenoz, M. G., Rubio, C. Q., Ochoa, E. M., Blasco, M., Duran, J. G., Vanrell, J. M., Reina, J., Castrillejo, D., Gherasim, A. M., Delgado, C., Oliva, J., Casas, I., Garcia, M., Latorre, M., Beamonte, A. M. M., Sapina, A. M., Amores, M. O., Aizpurua, A., Montes, M., Zakikhany, K., Brytting, M., Wiman, A., Carnahan, A., Warburton, F., Djennad, A., Ellis, J., Andrews, N., Marques, D., Cottrell, S., Reynolds, A., Gunson, R., Galiano, M., Lackenby, A., Robertson, C., O'Doherty, M., Sinnathamby, M., Yonova, I., Moore, C., Sartaj, M., de Lusignan, S., Zambon, M., Moren, A., Penttinen, P., and Sanguinetti M. (ORCID:0000-0002-9780-7059)
- Abstract
Between September 2017 and February 2018, influenza A(H1N1)pdm09, A(H3N2) and B viruses (mainly B/Yamagata, not included in 2017/18 trivalent vaccines) co-circulated in Europe. Interim results from five European studies indicate that, in all age groups, 2017/18 influenza vaccine effectiveness was 25 to 52% against any influenza, 55 to 68% against influenza A(H1N1)pdm09, -42 to 7% against influenza A(H3N2) and 36 to 54% against influenza B. 2017/18 influenza vaccine should be promoted where influenza still circulates.
- Published
- 2018
20. Low 2016/17 season vaccine effectiveness against hospitalised influenza A(H3N2) among elderly: awareness warranted for 2017/18 season
- Author
-
Rondy, M., Gherasim, A., Casado, I., Launay, O., Rizzo, C., Pitigoi, D., Mickiene, A., Marbus, S. D., Machado, A., Syrjanen, R. K., Pem-Novose, I., Horvath, J. K., Larrauri, A., Castilla, J., Vanhems, P., Alfonsi, V., Ivanciuc, A. E., Kuliese, M., Van Gageldonk-Lafeber, R., Gomez, V., Ikonen, N., Lovric, Z., Ferenczi, A., Moren, A., Pozo, F., Garcia, M., Latorre, M., Omenaca, M., Oribe Amores, M., Munoz, N., Cilla, G., Fernandino, L., Martinez-Baz, I., Navascues, A., Perez-Garcia, A., Aguinaga, A., Ezpeleta, C., Bella, A., Appelgren, E. C., Castrucci, M. R., Puzelli, S., Chironna, M., Germinario, C., Ansaldi, F., Manini, I., Montomoli, E., Lupulescu, E., Lazar, M., Mihai, M. E., Cherciu, C. M., Dinu, S., Tecu, C., Nitescu, M., Bacruban, R., Azamfire, D., Dumitrescu, A., Ianosik, E., Ceausu, E., Popescu, C. P., Florescu, S. A., Tardei, G., Bejan, C., Teodor, A., Juganariu, G., Plesca, C., Duca, E., Lenzi, N., Lesieur, Z., Loulergue, P., Galtier, F., Agostini, C., Ray, M., Merle, C., Foulongne, V., Lina, B., Laine, F., De Guibert, S., Lagathu, G., Tattevin, P., Jouneau, S., Esvant, A., Le Gallou, T., Carrat, F., Mawuvi, G., Chau, F., Nohynek, H., Haveri, A., Gefenaite, G., Velyvyte, D., Jancoriene, L., Zablockiene, B., Ambrozaitis, A., Grimalauskaite, R., Damuleviciene, G., Lesauskaite, V., Bagdonas, A., Nunes, B., Kislaya, I., Rodrigues, A. P., Gomes, V., Corte-Real, R., Pocas, J., Peres, M. J., Bernard, K., Kurecic-Filipovic, S., Visekruna Vucina, V., Topic, A., Papic, N., Budimir, J., Oroszi, B., Meijer, A., Van Der Hoek, W., Schneeberger, P. M., EpiConcept [Paris], Institute of Health 'Carlos III', CIBER de Epidemiología y Salud Pública (CIBERESP), IDISNA, Pamplona, CIC Cochin Pasteur (CIC 1417), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Cochin [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôtel-Dieu-Université Paris Descartes - Paris 5 (UPD5)-Groupe hospitalier Broca-Institut National de la Santé et de la Recherche Médicale (INSERM), F-CRIN, Innovative clinical research network in vaccinology (I-REIVAC), Istituto Superiore di Sanità (ISS), University of Medicine and Pharmacy 'Carol Davila' Bucharest (UMPCD), Lithuanian University of health Sciences, National Institute for Public Health and the Environment [Bilthoven] (RIVM), Instituto Nacional de Saùde Dr Ricardo Jorge [Portugal] (INSA), National Institute for Health and Welfare [Helsinki], Croatian Institute of Public Health [Zagreb] (CIPH), Office of the Chief Medical Officer, Hôpital Edouard Herriot [CHU - HCL], Hospices Civils de Lyon (HCL), Laboratoire des pathogènes émergents -- Emerging Pathogens Laboratory (LPE-Fondation Mérieux), Centre International de Recherche en Infectiologie (CIRI), École normale supérieure de Lyon (ENS de Lyon)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Université Jean Monnet - Saint-Étienne (UJM)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-École normale supérieure de Lyon (ENS de Lyon)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Université Jean Monnet - Saint-Étienne (UJM)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Institute of Biology Bucharest of Romanian Academy, Epidemiology Department, Institut National de la Santé et de la Recherche Médicale (INSERM)-Groupe hospitalier Broca-Université Paris Descartes - Paris 5 (UPD5)-Hôtel-Dieu-Hôpital Cochin [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Istituto Superiore di Sanità Rome, Rome, Italy, Centre International de Recherche en Infectiologie - UMR (CIRI), Institut National de la Santé et de la Recherche Médicale (INSERM)-École normale supérieure - Lyon (ENS Lyon)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM)-École normale supérieure - Lyon (ENS Lyon)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Centre National de la Recherche Scientifique (CNRS), EpiConcept, Unión Europea, CIC Cochin Pasteur ( CIC 1417 ), Assistance publique - Hôpitaux de Paris (AP-HP)-CHU Cochin [AP-HP]-Hôtel-Dieu-Groupe hospitalier Broca-Institut National de la Santé et de la Recherche Médicale ( INSERM ) -Université Paris Descartes - Paris 5 ( UPD5 ), F-CRIN, I-REIVAC, Institut National de la Santé et de la Recherche Médicale ( INSERM ), National Center for Epidemiology Surveillance and Health Promotion, Istituto Superiore di Sanita [Rome], 'Carol Davila' University of Medicine and Pharmacy, National Institute for Public Health and the Environment [Bilthoven] ( RIVM ), Instituto Nacional de Saúde Doutor Ricardo Jorge, Croatian Institute of Public Health, Zagreb, Hospices Civils de Lyon ( HCL ), Centre International de Recherche en Infectiologie ( CIRI ), Centre National de la Recherche Scientifique ( CNRS ) -Institut National de la Santé et de la Recherche Médicale ( INSERM ) -Université Claude Bernard Lyon 1 ( UCBL ), Université de Lyon-Université de Lyon-École normale supérieure - Lyon ( ENS Lyon ), Istituto Superiore de Sanita, HAL-UPMC, Gestionnaire, École normale supérieure - Lyon (ENS Lyon)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-École normale supérieure - Lyon (ENS Lyon)-Université Claude Bernard Lyon 1 (UCBL), and Université de Lyon-Université de Lyon-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)
- Subjects
Male ,0301 basic medicine ,Pediatrics ,Epidemiology ,Efetividade da Vacina Antigripal ,A(H3N2) ,Influenza ,cases control ,elderly ,hospitalisation ,vaccine effectiveness ,Elderly ,0302 clinical medicine ,vaccine ,Outcome Assessment, Health Care ,Influenza A Virus ,Hospitalisation ,awareness ,030212 general & internal medicine ,media_common ,Vaccine effectiveness ,virus diseases ,[ SDV.SPEE ] Life Sciences [q-bio]/Santé publique et épidémiologie ,Middle Aged ,Hospitals ,3. Good health ,Hospitalization ,Influenza Vaccines ,H3N2 Subtype ,Female ,Seasons ,influenza ,Rapid Communication ,Human ,Adult ,medicine.medical_specialty ,Adolescent ,Influenza vaccine ,030106 microbiology ,Outcome Assessment (Health Care) ,03 medical and health sciences ,[SDV.IMM.VAC] Life Sciences [q-bio]/Immunology/Vaccinology ,Virology ,Influenza, Human ,medicine ,Aged ,European Union ,Humans ,Influenza A Virus, H3N2 Subtype ,media_common.cataloged_instance ,Vacina Antigripal ,European union ,Cases control ,Cases Control ,business.industry ,Public health ,Cuidados de Saúde ,Public Health, Environmental and Occupational Health ,Case-control study ,Influenza a ,Confidence interval ,[SDV.SPEE] Life Sciences [q-bio]/Santé publique et épidémiologie ,Emergency medicine ,[ SDV.IMM.VAC ] Life Sciences [q-bio]/Immunology/Vaccinology ,[SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie ,[SDV.IMM.VAC]Life Sciences [q-bio]/Immunology/Vaccinology ,Prevention control ,business - Abstract
Members of the I-Move+hospital working group - Portugal: B. Nunes, I. Kislaya, A.P. Rodrigues (National Health Institute Doutor Ricardo Jorge, Lisbon), V. Gomes, R. Côrte-Real (Centro Hospitalar de Lisboa Central, Lisbon), J. Poças, M.J. Peres (Centro Hospitalar de Setúbal, Setúbal). In a multicentre European hospital study we measured influenza vaccine effectiveness (IVE) against A(H3N2) in 2016/17. Adjusted IVE was 17% (95% confidence interval (CI): 1 to 31) overall; 25% (95% CI: 2 to 43) among 65-79-year-olds and 13% (95% CI: -15 to 30) among those ≥ 80 years. As the A(H3N2) vaccine component has not changed for 2017/18, physicians and public health experts should be aware that IVE could be low where A(H3N2) viruses predominate. Funding: The I-MOVE+ project has received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement No 634446. The Lithuanian I-MOVE+ study sites were supported by a grant from the Research Council of Lithuania (SEN-03/2015). info:eu-repo/semantics/publishedVersion
- Published
- 2017
21. Repeated seasonal influenza vaccination among elderly in Europe: Effects on laboratory confirmed hospitalised influenza
- Author
-
Rondy, M., Launay, O., Castilla, J., Costanzo, S., Puig-Barbera, J., Gefenaite, G., Larrauri, A., Rizzo, C., Pitigoi, D., Syrjanen, R. K., Machado, A., Filipovic, S. K., Horvath, J. K., Paradowska-Stankiewicz, I., Marbus, S., Moren, A., Valenciano, M., Lenzi, N., Lesieur, Z., Loulergue, P., Galtier, F., Ray, M., Foulongne, V., Letois, F., Merle, C., Vanhems, P., Lina, B., Casado, I., Diaz-Gonzalez, J., Guevara, M., Martinez-Baz, I., Fernandino, L., Navascues, A., Ezpeleta, C., Chamorro, J., Barrado, L., Ortega, M. T., De Gaetano Donati, K., Cauda, R., Donato, C., Taccari, F., Campana, L., Santangelo, R., Perlasca, F., Fichera, G., Dara, M., Iacoviello, L., Olivieri, M., Alfonsi, V., Bella, A., Puzelli, S., Castrucci, M. R., Orsi, A., Ansaldi, F., Manini, I., Montomoli, E., Chironna, M., Germinario, C., Diez-Domingo, J., Sanudo, B., Carratala Munuera, C., Correcher Medina, P., Gil Guillen, V., Larrea Gonzalez, R., Limon Ramirez, R., Mico Esparza, J. L., Mollar Maseres, J., Otero Reigada, M. C., Tortajada Girbes, M., Schwarz Chavarri, G., Ambrozaitis, A., Jancoriene, L., Zablockiene, B., Zagminas, K., Aukse, M., Damuleviciene, G., Grimalauskaite, R., Kuliese, M., Lesauskaite, V., Velyvyte, D., Niesters, H., Stolk, R. P., Zagmines, K., Rahamat-Langendoen, J., Gherasim, A., Pozo, F., Altzibar, J., Arraras, J. G., Cilla, G., Marco, E., Vidal Garcia, M., Omenaca, M., Ivanciuc, A. E., Lupulescu, E., Lazar, M., Cherciu, C. M., Tecu, C., Mihai, M. E., Nitescu, M., Leca, D., Ceausu, E., Nohynek, H., Ikonen, N., Haveri, A., Gomez, V., Nunes, B., Rodrigues, A. P., Gomes, V., Corte-Real, R., Pocas, J., Peres, M. J., Visekruna Vucina, V., Kaic, B., Novosel, I. P., Petrovic, G., Ferenczi, A., Oroszi, B., Korczynska, M. R., Brydak, L. B., Cieslik-Tarkota, R., Rozwadowska, B., Skolimowska, G., Hulboj, D., Jakubik, A., Meijer, A., Van Gageldonk-Lafeber, A. B., Research Council of Lithuania, and European Union
- Subjects
0301 basic medicine ,Male ,Veterinary medicine ,Immunology and Microbiology (all) ,medicine.disease_cause ,Polymerase Chain Reaction ,Aged ,Aged, 80 and over ,Case-Control Studies ,Clinical Laboratory Techniques ,Europe ,Female ,Hospitalization ,Humans ,Influenza A Virus, H1N1 Subtype ,Influenza A Virus, H3N2 Subtype ,Influenza B virus ,Influenza Vaccines ,Influenza, Human ,Respiratory Tract Infections ,Seasons ,Sentinel Surveillance ,Vaccination ,Molecular Medicine ,Veterinary (all) ,Public Health, Environmental and Occupational Health ,Infectious Diseases ,Seasonal influenza ,IMOVE+ ,0302 clinical medicine ,80 and over ,Influenza A Virus ,Influenza A virus ,030212 general & internal medicine ,Respiratory tract infections ,virus diseases ,3. Good health ,H3N2 Subtype ,Public Health ,Human ,medicine.medical_specialty ,Influenza vaccine ,030106 microbiology ,Virus ,Hospital ,03 medical and health sciences ,Repeated Vaccination ,Internal medicine ,medicine ,H1N1 Subtype ,Influenza Vaccine Effectiveness ,General Veterinary ,General Immunology and Microbiology ,business.industry ,Environmental and Occupational Health ,Cuidados de Saúde ,Case-control study ,Influenza ,Negative case ,influenza vaccination, test negative case control, vaccine effectiveness ,business - Abstract
In Europe, annual influenza vaccination is recommended to elderly. From 2011 to 2014 and in 2015-16, we conducted a multicentre test negative case control study in hospitals of 11 European countries to measure influenza vaccine effectiveness (IVE) against laboratory confirmed hospitalised influenza among people aged ≥65years. We pooled four seasons data to measure IVE by past exposures to influenza vaccination. We swabbed patients admitted for clinical conditions related to influenza with onset of severe acute respiratory infection ≤7days before admission. Cases were patients RT-PCR positive for influenza virus and controls those negative for any influenza virus. We documented seasonal vaccination status for the current season and the two previous seasons. We recruited 5295 patients over the four seasons, including 465A(H1N1)pdm09, 642A(H3N2), 278 B case-patients and 3910 controls. Among patients unvaccinated in both previous two seasons, current seasonal IVE (pooled across seasons) was 30% (95%CI: -35 to 64), 8% (95%CI: -94 to 56) and 33% (95%CI: -43 to 68) against influenza A(H1N1)pdm09, A(H3N2) and B respectively. Among patients vaccinated in both previous seasons, current seasonal IVE (pooled across seasons) was -1% (95%CI: -80 to 43), 37% (95%CI: 7-57) and 43% (95%CI: 1-68) against influenza A(H1N1)pdm09, A(H3N2) and B respectively. Our results suggest that, regardless of patients' recent vaccination history, current seasonal vaccine conferred some protection to vaccinated patients against hospitalisation with influenza A(H3N2) and B. Vaccination of patients already vaccinated in both the past two seasons did not seem to be effective against A(H1N1)pdm09. To better understand the effect of repeated vaccination, engaging in large cohort studies documenting exposures to vaccine and natural infection is needed. The Lithuanian I-MOVE+ study sites were supported by a grant from the Research Council of Lithuania (SEN-03/2015). The IMOVE+ project has received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement No 634446. GlaxoSmithKline, Sanofi Pasteur and Sanofi Pasteur MSD financially supported the InNHOVE network. They had no role in study design, data collection, pooled analysis, and publication. We are grateful to all patients, medical staff, study nurses and epidemiologists from the twelve study sites who actively participated in the study. info:eu-repo/semantics/publishedVersion
- Published
- 2017
22. 2015/16 seasonal vaccine effectiveness against hospitalisation with influenza A(H1N1)pdm09 and B among elderly people in Europe: results from the I-MOVE+ project
- Author
-
Rondy, Marc, Larrauri, A., Casado, I., Alfonsi, V., Pitigoi, D., Launay, O., Syrjänen, R. K., Gefenaite, G., Machado, A., Vučina, V. V., Horváth, J. K., Paradowska-Stankiewicz, I., Marbus, S. D., Gherasim, A., Díaz-González, J. A., Rizzo, C., Ivanciuc, A. E., Galtier, F., Ikonen, N., Mickiene, A., Gomez, V., Kurečić Filipović, S., Ferenczi, A., Korcinska, M. R., Van Gageldonk-Lafeber, R., Valenciano, M., Altzibar, Jone M., Arraras, Ion Garcia, Cilla, Gustavo, Marco, Elisa, Vidal, Matxalen, Omenaca, Manuel, Castilla, J., Navascues, A., Ezpeleta, C., Barrado, L., Ortega, M. T., Bella, A., Castrucci, M. R., Puzelli, S., Chironna, M., Germinario, C., Ansaldi, F., Orsi, A., Manini, I., Montomoli, E., Lupulescu, E., Lazar, M., Cherciu, C. M., Tecu, C., Mihai, M. E., Nitescu, M., Leca, D., Ceausu, E., Lenzi, N., Lesieur, Z., Loulergue, P., Foulongne, V., Letois, F., Merle, C., Vanhems, P., Lina, B., Nohynek, H., Haveri, A., Kuliese, M., Velyvyte, D., Grimalauskaite, R., Damuleviciene, G., Lesauskaite, V., Jancoriene, L., Zablockiene, B., Ambrozaitis, A., Nunes, B., Rodrigues, A. P., Gomes, V., Corte-Real, R., Pocas, J., Peres, M. J., Kaić, B., Oroszi, B., Brydak, L. B., Cieślak, K., Kowalczyk, D., Szymański, K., Jakubik, A., Skolimowska, G., Hulboj, D., Meijer, A., Van Der Hoek, W., Schneeberger, P. M., Palmieri, Annapina, Giannitelli, Stefania, Ranghiasci, Alessia, Bacruban, Rodica, Azamfire, Delia, Dumitrescu, Aura, Ianosik, Elena, Duca, Elena, Bejan, Codrina, Teodor, Andra, Florescu, Simin-Aysel, Popescu, Corneliu, Tardei, Gratiela, Charpentier, Julien, Marin, Nathalie, Doumenc, Benoit, Le Jeunne, Claire, Krivine, Anne, Momcilovic, Sonia, Benet, Thomas, Amour, Selilah, Henaff, Laetitia, Jokinen, Jukka, Lyytikainen, Outi, Palmu, Arto, Siren, Paivi, Ruokokoski, Esa, Nunes, Baltazar, Rodrigues, Ana Paula, Guiomar, Raquel, Gomes, Victor, Quaresma, Filipa, Vale, Luis, Garcia, Teresa, Bernardo, Teresa, Dias, Liliana, Fonseca, Paula, Amorim, Helena, Rolo, Joao, Pacheco, Helena, Branquinho, Paula, Corte-Real, Rita, Pocas, Jose, Lopes, Paula, Peres, Maria Joao, Ribeiro, Rosa, Duarte, Paula, Pedroso, Ermelinda, Rodrigues, Sara, Silverio, Ana Rita, Pedreira, Diana Gomes, Fonseca, Marta Ferreira, Vince, Adriana, Topić, Antea, Papić, Neven, Mihalić, Jelena Budimir, Novosel, Iva Pem, Petrović, Goranka, Zajec, Martina, Draženović, Vladimir, Hercegh, Eva, Szalai, Balint, Antmann, Katalin, Nagy, Kamilla, Unión Europea, EpiConcept, Institute of Health Carlos III, CIBER de Epidemiología y Salud Pública (CIBERESP), Istituto Superiore de Sanita, University of Medicine and Pharmacy 'Carol Davila' Bucharest (UMPCD), Hôpital Cochin [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Instituto Nacional de Saùde Dr Ricardo Jorge [Portugal] (INSA), CIC Montpellier, Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier)-CHU Saint-Eloi-Institut National de la Santé et de la Recherche Médicale (INSERM), F-CRIN, Innovative clinical research network in vaccinology (I-REIVAC), Institut National de la Santé et de la Recherche Médicale (INSERM), National Institute for Health and Welfare [Helsinki], and National Institute for Public Health and the Environment [Bilthoven] (RIVM)
- Subjects
Infecções Respiratórias ,0301 basic medicine ,Male ,Heart disease ,Epidemiology ,Efetividade da Vacina Antigripal ,0302 clinical medicine ,Influenza A Virus, H1N1 Subtype ,[SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseases ,Outcome Assessment, Health Care ,80 and over ,Influenza A Virus ,Medicine ,030212 general & internal medicine ,Aged, 80 and over ,[SDV.MHEP.GEG]Life Sciences [q-bio]/Human health and pathology/Geriatry and gerontology ,Vaccination ,virus diseases ,3. Good health ,Europe ,Hospitalization ,Influenza Vaccines ,case control ,elderly ,hospitalisation ,influenza ,severe acute respiratory infection ,vaccine effectiveness ,vaccine-preventable diseases ,Vaccine-preventable diseases ,Female ,Public Health ,Seasons ,Research Article ,Human ,medicine.medical_specialty ,Influenza vaccine ,030106 microbiology ,Aged ,Humans ,Influenza B virus ,Influenza, Human ,Logistic Models ,Outcome Assessment (Health Care) ,Sentinel Surveillance ,Vaccine Potency ,Public Health, Environmental and Occupational Health ,Virology ,Hospital ,03 medical and health sciences ,Diabetes mellitus ,Internal medicine ,H1N1 Subtype ,Vacina Antigripal ,Intensive care medicine ,business.industry ,Environmental and Occupational Health ,Cuidados de Saúde ,Case-control study ,medicine.disease ,Influenza ,Confidence interval ,[SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie ,[SDV.IMM.VAC]Life Sciences [q-bio]/Immunology/Vaccinology ,business - Abstract
Members of the I-MOVE+ project - Portugal: Baltazar Nunes, Ana Paula Rodrigues, Raquel Guiomar (Infectious Diseases Department, National Health Institute Doutor Ricardo Jorge, Lisbon, Portugal), Victor Gomes, Filipa Quaresma, Luis Vale, Teresa Garcia, Teresa Bernardo, Liliana Dias, Paula Fonseca, Helena Amorim, João Rolo, Helena Pacheco, Paula Branquinho, Rita Côrte-Real (Centro Hospitalar de Lisboa Central, Lisbon, Portugal),José Poças, Paula Lopes, Maria João Peres, Rosa Ribeiro, Paula Duarte, Ermelinda Pedroso, Sara Rodrigues, Ana Rita Silvério, Diana Gomes Pedreira, Marta Ferreira Fonseca, (Centro Hospitalar de Setúbal, Setúbal, Portugal). We conducted a multicentre test-negative case-control study in 27 hospitals of 11 European countries to measure 2015/16 influenza vaccine effectiveness (IVE) against hospitalised influenza A(H1N1)pdm09 and B among people aged ≥ 65 years. Patients swabbed within 7 days after onset of symptoms compatible with severe acute respiratory infection were included. Information on demographics, vaccination and underlying conditions was collected. Using logistic regression, we measured IVE adjusted for potential confounders. We included 355 influenza A(H1N1)pdm09 cases, 110 influenza B cases, and 1,274 controls. Adjusted IVE against influenza A(H1N1)pdm09 was 42% (95% confidence interval (CI): 22 to 57). It was 59% (95% CI: 23 to 78), 48% (95% CI: 5 to 71), 43% (95% CI: 8 to 65) and 39% (95% CI: 7 to 60) in patients with diabetes mellitus, cancer, lung and heart disease, respectively. Adjusted IVE against influenza B was 52% (95% CI: 24 to 70). It was 62% (95% CI: 5 to 85), 60% (95% CI: 18 to 80) and 36% (95% CI: -23 to 67) in patients with diabetes mellitus, lung and heart disease, respectively. 2015/16 IVE estimates against hospitalised influenza in elderly people was moderate against influenza A(H1N1)pdm09 and B, including among those with diabetes mellitus, cancer, lung or heart diseases. The I-MOVE+ project has received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement No 634446. info:eu-repo/semantics/publishedVersion
- Published
- 2017
23. Thin walled pottery from Alife (Northern Campania, Italy)
- Author
-
Grifa, C, De Bonis, A, Guarino, V, Petrone, CM, Germinario, C, Mercurio, M, Soricelli, G, Langella, A, Morra, V, Grifa, C., DE BONIS, Alberto, Guarino, Vincenza, Petrone, C. M., Germinario, C., Mercurio, M., Soricelli, G., Langella, A., and Morra, Vincenzo
- Subjects
Thin walled pottery ,Alife ,Volturno river clays ,Grain Size Analyses ,levigation ,Thin walled pottery, Alife, Volturno river clays, Grain Size Analyses, levigation ,Volturno river clay ,Grain Size analyse - Abstract
The ancient town of Allifae (modern Alife) represents one of the most interesting settlements of the Northern Campania area that, together with the ancient city of Cales, was a thriving production centre of pottery. Excavations carried out inside the city wall, near the south gate, the so-called Porta Fiume, unearthed a huge dump of thin walled ware where the most abundant forms were cups and beakers, decorated with grooves or rouletting. The dump has been dated Augustan/ early Tiberian age (20 b.C.- 20 AD) and the thin walled vessels found can be identified with similar wares from Allifae, Cubulteria, Caiatia and perhaps Neapolis. Horace in his Sermones (II, 8,39) cited the Allifana beakers (described as fictiles ac subtiles by a Horace scholiast) and they could possibly be identified with the thin walled wares produced in Allifae. If this the case, then the thin walled vessels produced in Allifae were known in Rome as early as the end of I century B.C. In order to investigate and characterise the Allifae thin-walled pottery, twenty-one samples were selected and mineralogical-petrographic analyses (OM, XRPD, XRF and SEM/EDS) were carried out. The clayey raw material used was a low-CaO alluvial clayey deposit from the Middle Valley of the Volturno River. The potters probably handled the sediment by a levigation process in order to remove the coarser grains, and making the clay suitable to produce such thin walls. Comparison with other regional production of thin-walled pottery allowed us to strictly distinguish the Allifana beakers.
- Published
- 2015
24. Results of diagnostic campaign promoted by AIAr in the deposits of the Archaeological Museum of Paestum
- Author
-
Oddo, M. E, primary, Ricci, P., additional, Angelici, D., additional, Fantino, F., additional, Sibilia, E., additional, Alberghina, M. F, additional, Schiavone, S., additional, Grifa, C., additional, Mercurio, M., additional, Germinario, C., additional, Izzo, F., additional, Langella, A., additional, Massa, E., additional, Bracci, S., additional, Magrini, D., additional, Costa, R., additional, Pelagotti, A., additional, Zuchtriegel, G., additional, and Lubritto, C., additional
- Published
- 2018
- Full Text
- View/download PDF
25. Thin walled pottery from Alife (Northern Campania, Italy)
- Author
-
Grifa, C, De Bonis, A, Guarino, V, Petrone, CM, Germinario, C, Mercurio, M, Soricelli, G, Langella, A, Morra, V, Grifa, C, De Bonis, A, Guarino, V, Petrone, CM, Germinario, C, Mercurio, M, Soricelli, G, Langella, A, and Morra, V
- Abstract
The file attached is the published version of the article., NHM Repository
- Published
- 2017
26. Archaeometric characterization of common wares from Ancient Appia Landscapes Survey (Benevento - Italy): new elements to reconstruct a Late Roman micro-regional ceramic production
- Author
-
Germinario, C., Cultrone, C., Izzo, F., Langella, A., Mercurio, M., Morra, V., Santoriello, A., Siano, Stefania, Tomay, L., and Grifa, Celestino
- Published
- 2015
27. Epidemiology of Pulmonary Embolism in Apulia from analysis of current data
- Author
-
Moretti, A.M., primary, Tafuri, S., additional, Parisi, D., additional, and Germinario, C., additional
- Published
- 2016
- Full Text
- View/download PDF
28. Health-related quality of life (HRQoL), pain and function of patients with hip replacement
- Author
-
Balducci, MT, Mudoni, S, Nigro, M, Parisi, D, Luzi, I, Torre, M, Germinario, C, Balducci, MT, Mudoni, S, Nigro, M, Parisi, D, Luzi, I, Torre, M, and Germinario, C
- Published
- 2015
29. Community-wide outbreak of haemolytic uraemic syndrome associated with Shiga toxin 2-producing Escherichia coli O26:H11 in southern Italy, summer 2013.
- Author
-
Germinario, C., Caprioli, A., Giordano, M., Chironna, M., Gallone, M. S., Tafuri, S., Minelli, F., Maugliani, A., Michelacci, V., Santangelo, L., Mongelli, O., Montagna, C., and Scavia, G.
- Published
- 2016
- Full Text
- View/download PDF
30. The Tomb of the Diver and the frescoed tombs in Paestum (southern Italy): New insights from a comparative archaeometric study
- Author
-
Carmine Lubritto, R. C. Ponterio, Emanuela Massa, Francesco Izzo, Salvatore Schiavone, Viviana Mollica Nardo, Mariano Mercurio, Silvestro Antonio Ruffolo, Celestino Grifa, Susanna Bracci, Maria Francesca Alberghina, Mauro Francesco La Russa, Antonio Spagnuolo, Anna Pelagotti, Paola Ricci, Gabriel Zuchtriegel, Donata Magrini, Maria Emanuela Oddo, Carmela Vetromile, Giovanni Bartolozzi, Chiara Germinario, Stefano Maria Pagnotta, Natalia Rovella, Alberghina, M. F., Germinario, C., Bartolozzi, G., Bracci, S., Grifa, C., Izzo, F., la Russa, M. F., Magrini, D., Massa, E., Mercurio, M., Nardo, V. M., Oddo, M. E., Pagnotta, S. M., Pelagotti, A., Ponterio, R. C., Ricci, P., Rovella, N., Ruffolo, S. A., Schiavone, S., Spagnuolo, A., Vetromile, C., Zuchtriegel, G., Lubritto, C., Alberghina M. F., Germinario C., Bartolozzi G., Bracci S., Grifa C., Izzo F., la Russa M. F., Magrini D., Massa E., Mercurio M., Nardo V. M., Oddo M. E., Pagnotta S. M., Pelagotti A., Ponterio R. C., Ricci P., Rovella N., Ruffolo S. A., Schiavone S., Spagnuolo A., Vetromile C., Zuchtriegel G., and Lubritto C.
- Subjects
Pigments ,History ,Light ,Raw Materials ,Social Sciences ,02 engineering and technology ,01 natural sciences ,archaeometric study ,Painting ,Paestum, archaeometry, the tomb of Diver ,Parallels ,Materials ,History, Ancient ,Minerals ,Multidisciplinary ,Physics ,Electromagnetic Radiation ,Calcite ,Historical Article ,021001 nanoscience & nanotechnology ,Built Structures ,Mineralogy ,Chemistry ,Archaeology ,Italy ,paestum ,Physical Sciences ,Medicine ,Engineering and Technology ,0210 nano-technology ,Human ,Research Article ,Chemical Elements ,Visible Light ,Context (archaeology) ,Structural Engineering ,Science ,Materials Science ,Ancient history ,Research and Analysis Methods ,Humans ,Chemical Characterization ,tomb of the diver ,010401 analytical chemistry ,0104 chemical sciences ,Temperature Analysis ,Earth Sciences ,frescoed tombs ,Paintings - Abstract
The Tomb of the Diver has been subject for many decades of fierce debate among archaeologists and classicists. Since its discovery in 1968, some scholars have considered it a unique example of the lost tradition of Greek painting, others have emphasized Etruscan or Italic parallels. More recently, a possible local production has been suggested. With the aim of trying to solve the archaeological question, an archaeometric comparison among this well-known artwork and several frescoed tombs coming from Hellenistic and Lucan necropolis was carried out. The multi-analytical study was focused on the identification of peculiar features of executive techniques and raw materials since the first period of the archaeological site. The analytical investigation has been preliminary based on a non-destructive approach, performed in-situ by portable equipment including imaging diagnostics and compositional spectroscopic techniques for identifying pigments and the conservation state of original painted surface; subsequently, a further deepening by using destructive techniques was performed in-lab for the mortar-based supports characterization. Archaeometric study suggested that technological choices slightly changed in a time span of about two centuries, highlighting important markers that allow clustering the contemporary artistic productions. Moreover, a comparison with mortars from temples decorations was provided to better understand the whole artistic context. The archaeometric data showed that the Tomb of the Diver could be traced back to a local artisanal tradition and therefore is neither Etruscan nor Greek, but the first and foremost an expression of the local elite culture of Paestum.
- Published
- 2020
31. Hospital discharges-based search of acute flaccid paralysis cases 2007-2016 in Italy and comparison with the National Surveillance System for monitoring the risk of polio reintroduction
- Author
-
Stefanelli, Paola, Bellino, Stefania, Fiore, Stefano, Fontana, Stefano, Amato, Concetta, Buttinelli, Gabriele, Ansaldi, Filippo, Binda, Sandro, Pellegrinelli, Laura, Bonaccorsi, Guglielmo, Lorini, Chiara, Brusaferro, Silvio, Camilloni, Barbara, Capannolo, Benita, Mancini, Cristiana, Carraro, Valter, Castiglia, Paolo, Arghittu, Antonella, D'Errico, Marcello Mario, De Stefano, Carlo, Foca, Alfredo, CinziaGerminario, Larocca, Angela, Giammanco, Giovanni M, De Grazia, Simona, Grasso, Guido Maria, DanielaLombardi, Russo, Francesca, Napoletano, Giuseppina, Zanella, Francesca, Spertini, Silvia, Veronesi, Licia, Affanni, Paola, Triassi, Maria, Pennino, Francesca, Vairo, Francesco, Stefanelli, P., Bellino, S., Fiore, S., Fontana, S., Amato, C., Buttinelli, G., Ansaldi, F., Binda, S., Pellegrinelli, L., Bonaccorsi, G., Lorini, C., Brusaferro, S., Camilloni, B., Capannolo, B., Mancini, C., Carraro, V., Castiglia, P., Arghittu, A., D'Errico, M. M., De Stefano, C., Foca, A., Germinario, C., Larocca, A., Giammanco, G. M., De Grazia, S., Grasso, G. M., Lombardi, D., Russo, F., Napoletano, G., Zanella, F., Spertini, S., Veronesi, L., Affanni, P., Triassi, M., Pennino, F., Vairo, F., Stefanelli P., Bellino S., Fiore S., Fontana S., Amato C., Buttinelli G., Ansaldi F., Binda S., Pellegrinelli L., Bonaccorsi G., Lorini C., Brusaferro S., Camilloni B., Capannolo B., Mancini C., Carraro V., Castiglia P., Arghittu A., D'errico M.M., De Stefano C., Foca A., Germinario C., Larocca A., Giammanco G., De Grazia S., Grasso G.M., Lombardi D., Russo F., Napoletano G., Zanella F., Spertini S., Veronesi L., Affanni P., Triassi M., Pennino F., and Vairo F.
- Subjects
Male ,Settore MED/07 - Microbiologia E Microbiologia Clinica ,Pediatrics ,ERADICATION ,Acute flaccid paralysi ,0302 clinical medicine ,WORLDWIDE ,Epidemiology ,Paralysis ,Medicine ,030212 general & internal medicine ,Child ,Public, Environmental & Occupational Health ,0303 health sciences ,Polio ,lcsh:Public aspects of medicine ,Hospital Records ,Acute flaccid paralysis ,Patient Discharge ,Poliomyelitis ,Italy ,Child, Preschool ,Population Surveillance ,Female ,Diagnosis code ,medicine.symptom ,Hospital discharge record ,Life Sciences & Biomedicine ,Encephalitis ,Research Article ,Human ,medicine.medical_specialty ,Adolescent ,Myelitis ,03 medical and health sciences ,Poliomyelitis eradication ,Hospital discharge records ,Hospital Record ,Humans ,National surveillance system ,Preschool ,Science & Technology ,030306 microbiology ,business.industry ,Public Health, Environmental and Occupational Health ,Infant ,lcsh:RA1-1270 ,medicine.disease ,Paralysi ,Poliomyeliti ,business - Abstract
Background Acute flaccid paralysis (AFP) surveillance has been adopted globally as a key strategy for monitoring the progress of the polio eradication initiative. Hereby, to evaluate the completeness of the ascertainment of AFP cases in Italy, a hospital-discharges based search was carried out. Methods AFP cases occurring between 2007 and 2016 among children under 15 years of age were searched in the Italian Hospital Discharge Records (HDR) database using specific ICD-9-CM diagnostic codes. AFP cases identified between 2015 and 2016 were then compared with those notified to the National Surveillance System (NSS). Results Over a 10-year period, 4163 hospital discharges with diagnosis of AFP were reported in Italy. Among these, 956 (23.0%) were acute infective polyneuritis, 1803 (43.3%) myopathy, and 1408 (33.8%) encephalitis, myelitis and encephalomyelitis. During the study period, a decreasing trend was observed for all diagnoses and overall the annual incidence rate (IR) declined from 5.5 to 4.5 per 100,000 children. Comparing NSS with HDR data in 2015–2016, we found a remarkable underreporting, being AFP cases from NSS only 14% of those recorded in HDR. In particular, the acute infective polyneuritis cases reported to NSS accounted for 42.6% of those detected in HDR, while only 0.9% of myopathy cases and 13.1% of encephalitis/myelitis/encephalomyelitis cases have been notified to NSS. The highest AFP IRs per 100,000 children calculated on HDR data were identified in Liguria (17.4), Sicily (5.7), and Veneto (5.1) Regions; regarding the AFP notified to the NSS, 11 out of 21 Regions failed to reach the number of expected cases (based on 1/100,000 rate), and the highest discrepancies were observed in the Northern Regions. Overall, the national AFP rate was equal to 0.6, therefore did not reach the target value. Conclusions AFP surveillance data are the final measure of a country’s progress towards polio eradication. The historical data obtained by the HDR have been useful to assess the completeness of the notification data and to identify the Regions with a low AFP ascertainment rate in order to improve the national surveillance system.
- Published
- 2019
32. Multi-analytical characterization and provenance identification of protohistoric metallic artefacts from Picentia-Pontecagnano and the Sarno valley sites, Campania, Italy
- Author
-
Serenella Scala, Maria Carmela Del Re, Giovanni Di Maio, Chiara Germinario, Celestino Grifa, Alessio Langella, Mariano Mercurio, Roberto de Gennaro, Igor M. Villa, Carmela Petti, Giuseppina Balassone, Balassone, G., Mercurio, M., Germinario, C., Grifa, C., Villa, I. M., Di Maio, G., Scala, S., de Gennaro, R., Petti, C., Del Re, M. C., Langella, A., Balassone, G, Mercurio, M, Germinario, C, Grifa, C, Villa, I, Di Maio, G, Scala, S, de’ Gennaro, R, Petti, C, Del Re, M, and Langella, A
- Subjects
010506 paleontology ,Provenance ,engineering.material ,01 natural sciences ,Tin bronze ,GEO/08 - GEOCHIMICA E VULCANOLOGIA ,550 Earth sciences & geology ,0601 history and archaeology ,Metal object ,Bronze ,Electrical and Electronic Engineering ,Sarno valley ,Instrumentation ,0105 earth and related environmental sciences ,060102 archaeology ,Applied Mathematics ,06 humanities and the arts ,Condensed Matter Physics ,Archaeology ,Characterization (materials science) ,Ore provenance ,Pontecagnano ,engineering ,Spectroscopic technique ,Southern Italy ,Geology - Abstract
Protohistoric metal objects coming from the archaeological sites of Pontecagnano (Salerno, Italy) and Striano (Naples, Italy), preserved in the Pontecagnano National Archaeological Museum and the Paleontological Museum of Naples University “Federico II” have been studied by means of an archaeometric approach. A multi-analytical procedure including X-ray powder diffraction (XRPD), scanning electron microscopy and energy dispersive X-ray spectroscopy (SEM-EDS), micro X-ray fluorescence (µ-XRF) and lead isotope ratio mass spectrometry (LIRMS), was used to characterize these objects thus providing hypotheses on the possible provenance of metallic raw materials. The investigated samples are represented by lead, silver, copper and tin bronze-based objects. Corrosion processes affecting the bronze objects were recognized as well as crusts and patinae at different stages of evolution. LIRMS analyses suggested that most of Pontecagnano artifacts were manufactured with metals from southern Tuscany, where important metal reserves were located. On the other hand, due to the limited number of samples, the provenance of the Striano objects cannot be unambiguously identified although data so far available suggest a Sardinian source.
- Published
- 2018
33. Results of diagnostic campaign promoted by AIAr in the deposits of the Archaeological Museum of Paestum
- Author
-
D. Angelici, G. Zuchtriegel, Susanna Bracci, Anna Pelagotti, Emanuela Sibilia, Salvatore Schiavone, Alessio Langella, Celestino Grifa, M. E. Oddo, Francesco Izzo, Donata Magrini, R. Costa, Mariano Mercurio, Chiara Germinario, F. Fantino, Maria Francesca Alberghina, Carmine Lubritto, Emanuela Massa, Paola Ricci, Oddo, M. E., Ricci, P., Angelici, D., Fantino, F., Sibilia, E., Alberghina, M. F., Schiavone, S., Grifa, C., Mercurio, M., Germinario, C., Izzo, F., Langella, A., Massa, E., Bracci, S., Magrini, D., Costa, R., Pelagotti, A., Zuchtriegel, G., Lubritto, C., Oddo, M, Ricci, P, Angelici, D, Fantino, F, Sibilia, E, Alberghina, M, Schiavone, S, Grifa, C, Mercurio, M, Germinario, C, Izzo, F, Langella, A, Massa, E, Bracci, S, Magrini, D, Costa, R, Pelagotti, A, Zuchtriegel, G, and Lubritto, C
- Subjects
FORS ,Engineering (all) ,VIL imaging techniques ,media_common.quotation_subject ,XRF ,Materials Science (all) ,Art ,TR-FTIR ,Thermoluminescence dating ,Raman ,Archaeology ,Ancient technologies, Paestum ,media_common - Abstract
Thirty artefacts from the Archaeological Park of Paestum were investigated by means of scientific techniques on the occasion of the 2016 exhibition 'Possessione. Trafugamenti e falsi di antichita a Paestum'. The multi-analytic diagnostic campaign was aimed at identifying forgeries. Results provided a deeper understanding of both ancient technology and contemporary forgery techniques.
- Published
- 2018
34. Identifying Original and Restoration Materials through Spectroscopic Analyses on Saturnino Gatti Mural Paintings: How Far a Noninvasive Approach Can Go
- Author
-
Letizia Bonizzoni, Simone Caglio, Anna Galli, Chiara Germinario, Francesco Izzo, Donata Magrini, Bonizzoni, L, Caglio, S, Galli, A, Germinario, C, Izzo, F, and Magrini, D
- Subjects
Fluid Flow and Transfer Processes ,FORS ,Process Chemistry and Technology ,XRF ,ER-FTIR ,General Engineering ,Italian Archaeometry Association ,FIS/07 - FISICA APPLICATA (A BENI CULTURALI, AMBIENTALI, BIOLOGIA E MEDICINA) ,mural painting ,Saturnino Gatti ,Raman spectroscopy ,pigments ,binders ,Computer Science Applications ,pigment ,General Materials Science ,Instrumentation - Abstract
This paper presents the results obtained for the mural paintings (XV century CE) in the church of San Panfilo in Villagrande di Tornimparte (AQ, Italy) by means of noninvasive spectroscopic techniques; this research is a part of the project on the Saturnino Gatti pictorial cycle, promoted and coordinated by the AIAr (the Italian Archaeometry Association). Digital optical microscopy (OM), X-ray fluorescence spectroscopy (XRF), fiber optics reflectance spectroscopy in the UV–Vis–NIR range (FORS), Fourier transform infrared spectroscopy in the external reflection mode (ER-FTIR), and Raman spectroscopy were performed on the points selected based on the image analysis results and the few available records on previous intervention, with the aim of characterizing both the original and restoration organic and inorganic materials. The synergic application of complementary techniques allowed us to obtain a complete picture of the palette and the main alteration products and organic substances (of rather ubiquitous lipid materials and less widespread resin and proteinaceous materials in specific points). The identification of modern compounds permitted the individuation of restoration areas; this was confirmed by the comparison with multiband imaging results, as in the case of specific green and blue pigments, strictly related to the presence of high signals of zinc. This analytical protocol left only very few ambiguities and allowed to minimizing the number of samples taken to clarifying, by sample laboratory analyses, the few doubts still open.
- Published
- 2023
- Full Text
- View/download PDF
35. May a comprehensive mineralogical study of a jackstone calculus and some other human bladder stones unveil health and environmental implications?
- Author
-
Ettore Varricchio, P. Saldutto, Giacomo Diego Gatta, Francesco Izzo, Celestino Grifa, Mariano Mercurio, L. Salzano, A. Langella, A. Carafa, G. Lotrecchiano, Chiara Germinario, Maria Chiara Di Meo, Mercurio, M., Izzo, F., Gatta, Giacomo Diego, Salzano, L., Lotrecchiano, G., Saldutto, P., Germinario, C., Grifa, C., Varricchio, E., Carafa, A., Di Meo, Maria Chiara, and Langella, A.
- Subjects
Environmental Engineering ,Human bladder ,chemistry.chemical_element ,Environmental pollution ,General Medicine ,medicine.disease ,Mercury (element) ,chemistry ,Geochemistry and Petrology ,Biomonitoring ,medicine ,Calculus ,Environmental Chemistry ,Environmental science ,Bladder stones ,Calculus (medicine) ,Bladder stone ,General Environmental Science ,Water Science and Technology ,Contaminated food - Abstract
This paper represents the first result of an active collaboration between the University of Sannio and the San Pio Hospital (Benevento, Italy), started in the 2018, that aims to a detailed mineralogical investigation of urinary stones of patients from Campania region. Herein, selected human bladder stones have been deeply characterized for clinical purposes and environmental biomonitoring, focusing on the importance to evaluate the concentration and distribution of undesired trace elements by means of microscopic techniques in the place of conventional wet chemical analyses. A rare bladder stones with a sea-urchin appearance, known as jackstone calculus, were also investigated (along with bladder stones made of uric acid and brushite) by means a comprehensive analytical approach, including Synchrotron X-ray Diffraction and Simultaneous Thermal Analyses. Main clinical assumptions were inferred according to the morpho-constitutional classification of bladder stones and information about patient’s medical history and lifestyle. In most of the analyzed uroliths, undesired trace elements such as copper, cadmium, lead, chromium, mercury and arsenic have been detected and generally attributable to environmental pollution or contaminated food. Simultaneous occurrence of selenium and mercury should denote a methylmercury detoxification process, probably leading to the formation of a very rare HgSe compound known as tiemannite.
- Published
- 2021
36. Production technology of late Roman decorated tableware from the Vesuvius environs: Evidence from Pollena Trocchia (Campania region, Italy)
- Author
-
Chiara Germinario, Giuseppe Cultrone, G. De Simone, Vincenzo Brescia Morra, M. Gorrasi, Alessio Langella, C. S. Martucci, Celestino Grifa, Christopher R. Vyhnal, Francesco Izzo, Mariano Mercurio, A De Bonis, Germinario, C., Cultrone, G., De Bonis, A., De Simone, G. F., Gorrasi, M., Izzo, F., Langella, A., Martucci, C. S., Mercurio, M., Morra, V., Vyhnal, C. R., and Grifa, C.
- Subjects
ceramic technology ,Archeology ,Thesaurus (information retrieval) ,decorated pottery ,Earth and Planetary Sciences (miscellaneous) ,Pollena Trocchia ,Vesuvius environs ,Ancient history ,late Roman period ,Geology - Abstract
The northern slope of Mt. Vesuvius contains some interesting archaeological sites, including the site discovered in the town of Pollena Trocchia, where the remains, dated to between the 79 and 472 CE eruptions, document the transition from the Roman to late Roman cultural and socioeconomic settings. Profound changes occurred in this time interval, which can be inferred from changes in the ceramic manufacturing processes. Common wares, as the most widespread ceramic class in the archaeological record, are a useful example that illustrates this technological transformation. Seventeen samples of tableware, distinguished into three ceramic classes according to the method of slip application (i.e., Slipped Ware, Painted Ware “a straccio,” and Painted Ware), were analyzed. The results highlight the use of high-CaO clayey raw materials compositionally similar to Apennine clayey deposits. The clay bodies were occasionally tempered with sandy-silt materials composed of volcanic grains with lesser amounts of siliciclastic fragments. Firing temperatures ranged from 800 to 950°C, as suggested by quantitative X-ray powder diffraction and microstructural analyses combined with colorimetric measurements of the ceramic bodies. Micro-Raman analyses performed on slips revealed the use of ochre for decorating the vessels; it was applied in a different way, representing an actual technological change.
- Published
- 2020
37. Chabazite from Campanian Ignimbrite Tuff as a Potential and Sustainable Remediation Agent for the Removal of Emerging Contaminants from Water
- Author
-
Francesco Izzo, Alessio Langella, Bruno de Gennaro, Chiara Germinario, Celestino Grifa, Concetta Rispoli, Mariano Mercurio, Izzo, F., Langella, A., de Gennaro, B., Germinario, C., Grifa, C., Rispoli, C., and Mercurio, M.
- Subjects
Circular economy ,Environmental effects of industries and plants ,Renewable Energy, Sustainability and the Environment ,NSAIDs ,Geography, Planning and Development ,Water ,TJ807-830 ,zeolites ,chabazite-rich tuff ,Environment ,Management, Monitoring, Policy and Law ,minerals ,TD194-195 ,NSAID ,Renewable energy sources ,Green revolution and ecology transition ,Environmental sciences ,SMNZ ,ibuprofen ,green revolution and ecology transition ,water ,environment ,circular economy ,GE1-350 ,Mineral - Abstract
The technological performance of a chabazite-rich rock belonging to the Campanian Ignimbrite formation, outcropping in the nearby of San Mango sul Calore (southern Italy), has been evaluated for the sorption and release of ibuprofen sodium salt after a surface modification of the starting geomaterial using two different chlorinated surfactants. Equilibrium sorption isotherms and in vitro loading tests demonstrated that the maximum sorption capacities of this geomaterial reach up to 24.5 and 13.5 mg/g, respectively, for zeolite modified with cetylpyridinium and benzalkonium. These results, obtained by non-linear mathematical modeling of the experimental curves, are definitely compatible with the concentrations of the most common non-steroidal anti-inflammatory drugs (such as ibuprofen) in wastewaters, which have been recently considered as contaminants of emerging concern. This investigation also encourages a new possible sustainable exploitation of the lithified yellow facies of Campanian Ignimbrite, although future developments will be focused on using more stable and eco-friendlier two-tailed surfactants.
- Published
- 2022
38. Roman technological expertise in the construction of perpetual buildings: new insights into the wall paintings of a banquet scene from a tomb in Cumae (southern Italy)
- Author
-
Chiara Germinario, Sabrina Pagano, Mariano Mercurio, Francesco Izzo, Alberto De Bonis, Vincenzo Morra, Priscilla Munzi, Marcella Leone, Elisa Conca, Celestino Grifa, Germinario, C., Pagano, S., Mercurio, M., Izzo, F., De Bonis, A., Morra, V., Munzi, P., Leone, M., Conca, E., and Grifa, C.
- Subjects
Archeology ,Anthropology - Published
- 2022
39. A banquet scene in a tomb of Cuma (southern Italy): the study of wall paintings to shed light on Roman technological skills in 'building for eternity'
- Author
-
Chiara Germinario, Sabrina Pagano, Mariano Mercurio, Francesco Izzo, Alberto De Bonis, Vincenzo Morra, Priscilla Munzi, Marcella Leone, Elisa Conca, Celestino Grifa, Germinario, C., Pagano, S., Mercurio, M., Izzo, F., De Bonis, A., Morra, V., Munzi, P., Leone, M., Conca, E., and Grifa, C.
- Abstract
Excavations at the north-eastern side of the city Cumae (modern Cuma) brought to light the Tomba del Banchetto per l’Eternità, a hypogeum chamber tomb with vaulted ceiling built in tuff blocks dated back to the first decades of the 1st century BCE. The exceptional nature of the discovery, resembling an Oscan tradition, is due to the peculiar decorative scheme, reporting a banquet scene and three funerary beds along with a table, reproducing a sort of triclinium.The investigation performed on decorated plasters, in situ by a spectroscopic approach and in-lab via minero-petrographic techniques, allowed us to infer the production technology of wall paintings and mortar-based support, and the type of pigments used for decorating the tomb.The multi-layered plasters were made with specific mix-designs in the different part of the tomb; similarly, different painting techniques were adopted according to the architectural scheme. In the lower part of the walls, lime cocciopesto mortars adhere on the tuff blocks, likely to lend better hydraulic properties to the mortar-based supports in humid and wet environments. This part of the tomb, as well as the funerary beds, was painted in red using the fresco technique. On the other hand, in the upper part of walls and on the vault, the arriccio layer, containing volcanic sand, was covered with a thick and white intonachino layer composed of lime binder, constituting the support for the pictorial layer, applied with a mezzo fresco technique.The investigation on pigments used for wall paintings points out to the use of a characteristic Roman palette, consisting of pure, natural and synthetic pigments (calcite, red and yellow ochre, hematite, organic black pigments, Egyptian blue), and skilful mixtures of colouring materials (mixture of yellow ochre and organic carbon black for the brown, mixture of kaolinite-rich clay, Egyptian blue, and Fe-oxides for grey and mixture of organic –madder- and inorganic pigments for pink).Geographical Coordinates: 40°51’3.13’’N; 14°3’27.33’’E
- Published
- 2022
40. The Mediterranean trading centre of Vivara (southern Italy): New insights on the production and circulation of pottery during the Bronze Age (16th – 15th century BCE)
- Author
-
Chiara Germinario, Alberto De Bonis, Celestino Grifa, Vincenza Guarino, Massimiliano Marazzi, Carla Pepe, Concetta Rispoli, Monica Scotto di Covella, Vincenzo Morra, Germinario, C., De Bonis, A., Grifa, C., Guarino, V., Marazzi, M., Pepe, C., Rispoli, C., Scotto di Covella, M., and Morra, V.
- Subjects
Vivara ,Archeology ,Tourmaline ,Bronze age pottery ,Mediterranean commercial route ,Phlegraean field - Abstract
The important discoveries at the recent archaeological excavations at Punta d'Alaca site in the west side of the Vivara island (Campania region) highlighted the presence of a Bronze Age thriving settlement attesting the development of a flourishing ceramic production, mainly specialized in the manufacturing of common wares. The archaeometric study performed on twenty representative samples by means of chemical and minero-petrographic techniques revealed that pottery was produced in-situ; however, locally-manufactured vessels here coexisted with imported ones. Coarse-textured, local potteries were made by low-CaO clays mixed with volcanic temper consistent with the volcanic products of Campanian volcanoes. The firing (likely a pit firing) was done in rough conditions, as proved by mineralogical evidence that suggest variable firing temperatures. In fact, low firing temperatures (
- Published
- 2022
41. Technology, exploitation and consumption of natural resources of traditional brick productions in Madagascar
- Author
-
Antonio Carafa, Francesco Izzo, Mariano Mercurio, Piero Bareschino, Francesco Pepe, Celestino Grifa, A. Langella, Chiara Germinario, Giuseppe Cultrone, Ciro Cucciniello, Vincenzo Brescia Morra, Grifa, C., Germinario, C., Mercurio, M., Izzo, F., Pepe, F., Bareschino, P., Cucciniello, C., Morra, V., Cultrone, G., Carafa, A., and Langella, A.
- Subjects
Consumption (economics) ,Brick ,Peat ,Sediment ,Building and Construction ,Raw material ,Fuel ,Natural resource ,Basic knowledge ,Clayey sediment ,Environmental protection ,Madagascar ,Environmental science ,General Materials Science ,Firing ,Natural resources ,Energy source ,Brick production ,Civil and Structural Engineering - Abstract
The history of brick manufacturing in Madagascar dates back to the early 1800 s when European colonisers imparted to the local population the basic knowledge for firing clayey sediment to obtain a more durable construction material. The evaluation of the entire production cycle accounting for the involved natural resources such as raw materials, fuels and derived bricks, represents the aim of this research started in 2015 and focused on both rural and urban contexts. Clayey raw materials from lateritic soils widely occur in central Madagascar whereas, in southern coastal sites, carbonate-bearing clays definitely prevail since their composition are influenced by the reef. Bricks are prepared on site with no additional manipulation of the base clay and, depending on the climatic conditions, the bricks are dried and fired from one week up to ten days. Furnaces are powered by rice husk in south-western part of the island whereas in central Madagascar the use of peat and wood was also recorded. The calorific performances of these common fuels allow achieving temperatures of 800–900 °C; however, the huge loss of heat due to the poor quality of the furnaces determine low equivalent firing temperatures (EFT) that negatively affect the quality of the bricks. The above described ceramic process has remained unchanged for more than 200 years and even if new social and economic opportunities arose, this unvirtuous system slowly (but inexorably) contributed to the impoverishment of important energy sources and, above all, of natural resources.
- Published
- 2021
42. Application of surfactant modified natural zeolites for the removal of salicylic acid—a contaminant of emerging concern
- Author
-
Danijela Smiljanić, Chiara Germinario, Milena Obradovic, Francesco Izzo, Milica Ožegović, Aleksandra Dakovic, Bruno De Gennaro, Smiljanic, D., Dakovic, A., Obradovic, M., Ozegovic, M., Izzo, F., Germinario, C., and de Gennaro, B.
- Subjects
emerging contaminants ,Technology ,Microscopy ,QC120-168.85 ,QH201-278.5 ,Salicylic acid ,Engineering (General). Civil engineering (General) ,Article ,TK1-9971 ,Emerging contaminant ,Surfactant modified natural zeolites (SMNZs) ,Descriptive and experimental mechanics ,General Materials Science ,Electrical engineering. Electronics. Nuclear engineering ,TA1-2040 ,surfactant modified natural zeolites (SMNZs) ,salicylic acid - Abstract
This work aimed to test composites (surfactant modified zeolites prepared by treatment of natural zeolites—clinoptilolite (IZ CLI) and/or phillipsite (PHIL75)-rich tuffs with two different amounts of cationic surfactants: cetylpyridinium chloride (CPyCl) and Arquad® 2HT-75 (ARQ)) for the adsorption of salicylic acid (SA)—a common contaminant of emerging concern. Adsorption of SA was studied at different initial drug concentrations (in the range of 2–100 mg/L) in water solution. The Langmuir isotherm model showed the highest adsorption was achieved by bilayer composite of IZ CLI and CPyCl—around 11 mg/g. Kinetic runs were performed by using the initial drug concentration of 20 mg/L in the time interval from 0 to 75 min and pseudo-second order had good correlation with experimental data. The influence of the four different temperatures on the SA adsorption was also investigated and thermodynamic parameters suggested that the adsorption drug onto composites is an exothermic and nonspontaneous process, followed by the decrease of randomness at the solid/liquid interface during the adsorption. Zeta potential and Fourier-transform infrared spectroscopy with attenuated total reflectance (FTIR-ATR) had been performed for the characterization of composites after adsorption of SA confirming the presence of the drug at composite surfaces.
- Published
- 2021
43. Ceramic building materials from the ancient Témesa (Calabria region, Italy): Raw materials procurement, mix-design and firing processes from the Hellenistic to Roman period
- Author
-
Chiara Germinario, Alberto De Bonis, Filippo Barattolo, Luigi Cicala, Luigi Franciosi, Francesco Izzo, Alessio Langella, Mariano Mercurio, Vincenzo Morra, Bianca Russo, Ilaria Cicchiello, Celestino Grifa, Germinario, C., De Bonis, A., Barattolo, F., Cicala, L., Franciosi, L., Izzo, F., Langella, A., Mercurio, M., Morra, V., Russo, B., Cicchiello, I., and Grifa, C.
- Subjects
Calabria region ,Archeology ,Ceramic building material ,Pian della Tirena ,Ceramic technology ,Provenance of raw materials - Abstract
Ceramic building materials (CBM) are interesting archaeological items for gathering the material culture identity and urban setting of the ancient populations since their production is generally related to the local availability of clayey raw materials and advancements of technological skills of ancient makers. This paper investigates the Hellenistic and Roman productions of ceramic building materials from the archaeological site of Témesa on the Tyrrhenian coastline of Calabria region (southern Italy), a settlement where a flourishing ceramic tradition has been attested for all of its occupation phases, from the late Archaic to the Roman period. Here, the local availability of clayey and sandy raw materials permitted the development of a thriving worksite. A combined study of mineralogical, petrographic and micropaleontological features of archaeological samples and geological raw materials collected nearby the archaeological settlement, permitted to constrain the raw materials sources, and investigate the technological level achieved between the second half of the 4th century BCE and the 3rd century CE. This study highlighted that most of CBM was made by mixing sands from a nearby fluvial deposit with upper Miocene clayey raw materials. Chemical composition and micropaleontological investigation of the foraminiferal content of archaeological samples and clays validated the possible exploitation of local raw materials. Textural parameters and the mineralogical assemblage of temper grains, characterized by the peculiar presence of metamorphic lithics, also attested the use of Savuto river sands. Ceramic technology accounts for a firing process at reasonably high temperatures, evidencing the good technological level of production. Moreover, the presence of samples characterized by mix-designs and mineralogical assemblages consistent with geological materials from Campania region witnesses the importation of ceramic materials from other sites, suggesting the existence of operating trades as already attested for other sites of Tyrrhenian coast.
- Published
- 2022
44. Poliovirus and Other Enteroviruses from Environmental Surveillance in Italy, 2009–2015
- Author
-
Viviana Balena, Karen Cristiano, Licia Veronesi, Paola Stefanelli, Carlo Pini, Gabriele Buttinelli, Stefano Fontana, Rita Frate, Roberto Delogu, Sabine Gamper, Pietro Mercurio, Paolo Castiglia, Francesca Pennino, Sandro Binda, Antonella Cicala, Concetta Amato, Josef Simeoni, Roberta Zoni, Andrea Battistone, Stefano Fiore, Maria Triassi, Laura Pellegrinelli, Lucia Fiore, Cinzia Germinario, Andrea Cossu, Delogu, R., Battistone, A., Buttinelli, G., Fiore, S., Fontana, S., Amato, C., Cristiano, K., Gamper, S., Simeoni, J., Frate, R., Pellegrinelli, L., Binda, S., Veronesi, L., Zoni, R., Castiglia, P., Cossu, A., Triassi, M., Pennino, F., Germinario, C., Balena, V., Cicala, A., Mercurio, P., Fiore, L., Pini, C., and Stefanelli, P.
- Subjects
0301 basic medicine ,Serotype ,Epidemiology ,viruses ,Health, Toxicology and Mutagenesis ,030106 microbiology ,Population ,Sewage ,Biology ,medicine.disease_cause ,complex mixtures ,03 medical and health sciences ,0302 clinical medicine ,Limit of Detection ,Virology ,Poliomyelitis eradication ,Enterovirus Infections ,medicine ,Humans ,030212 general & internal medicine ,Cities ,education ,Enteroviru ,Enterovirus ,education.field_of_study ,Transmission (medicine) ,business.industry ,Poliovirus ,Environmental surveillance ,virus diseases ,medicine.disease ,Citie ,Poliomyelitis ,Enterovirus Infection ,Poliomyeliti ,Italy ,Polioviru ,Enteroviruse ,business ,Environmental Monitoring ,Human ,Food Science - Abstract
Within the initiatives for poliomyelitis eradication by WHO, Italy activated an environmental surveillance (ES) in 2005. ES complements clinical Acute Flaccid Paralysis (AFP) surveillance for possible polio cases, detects poliovirus circulation in environmental sewage, and is used to monitor transmission in communities. In addition to polioviruses, the analyses comprised: (i) the monitoring of the presence of non-polio enteroviruses in sewage samples and (ii) the temporal and geographical distribution of the detected viruses. From 2009 to 2015, 2880 sewage samples were collected from eight cities participating in the surveillance. Overall, 1479 samples resulted positive for enteroviruses. No wild-type polioviruses were found, although four Sabin-like polioviruses were detected. The low degree of mutation found in the genomes of these four isolates suggests that these viruses have had a limited circulation in the population. All non-polio enteroviruses belonged to species B and the most frequent serotype was CV-B5, followed by CV-B4, E-11, E-6, E-7, CV-B3, and CV-B2. Variations in the frequency of different serotypes were also observed in different seasons and/or Italian areas. Environmental surveillance in Italy, as part of the 'WHO global polio eradication program', is a powerful tool to augment the polio surveillance and to investigate the silent circulation or the re-emergence of enteroviruses in the population.
- Published
- 2018
45. Surface modified natural zeolites (SMNZs) as nanocomposite versatile materials for health and environment
- Author
-
Bruno de Gennaro, Paolo Aprea, Aleksandra Daković, Alessio Langella, Danijela Smiljanic, Chiara Germinario, Francesco Izzo, Mariano Mercurio, Celestino Grifa, Piergiulio Cappelletti, Izzo, F., Mercurio, M., de Gennaro, B., Aprea, P., Cappelletti, P., Dakovic, A., Germinario, C., Grifa, C., Smiljanic, D., and Langella, A.
- Subjects
Surface Properties ,Ibuprofen ,02 engineering and technology ,Wastewater ,01 natural sciences ,Non-linear regression ,Nanocomposites ,Surface-Active Agents ,Colloid and Surface Chemistry ,Adsorption ,Pulmonary surfactant ,Surfactant ,0103 physical sciences ,Animals ,Humans ,Physical and Theoretical Chemistry ,Zeolite ,chemistry.chemical_classification ,Toth ,Nanocomposite ,010304 chemical physics ,Chemistry ,Bilayer ,Anti-Inflammatory Agents, Non-Steroidal ,Cationic polymerization ,Sorption ,Surfaces and Interfaces ,General Medicine ,021001 nanoscience & nanotechnology ,Bayesian information criterion ,NSAID ,Emerging contaminant ,Gastrointestinal Tract ,Drug Liberation ,Kinetics ,Chemical engineering ,Sip ,Zeolites ,Nižný hrabovec ,Counterion ,0210 nano-technology ,Hydrophobic and Hydrophilic Interactions ,Biotechnology - Abstract
The present research deals with the evaluation of a clinoptilolite-rich rock, occurring in the Nižný Hrabovec deposit (Slovakia), for high-value technological applications based on sorption and in vitro release of nonsteroidal anti-inflammatory drugs (i.e., ibuprofen sodium salt). This georesource was surface modified (SMNZ) using four cationic surfactants. Results demonstrate that ibuprofen sorption is very fast and SMZNs can sorb up to ˜26 mg/g of drug as a function of the type of counterion and morphology of surfactant, as well as the hydrophobicity and molecular structure of the drug. Maximum sorption capacities observed for all SMNZs are fully comparable to other adsorbent carriers usually used for removal of contaminants in wastewaters. Sorption of ibuprofen is controlled by a dual mechanism: external anionic exchange and partition into the hydrophobic portion of the patchy bilayer. A prompt drug release in simulated intestinal fluid (SIF) was also observed, making this natural material also suitable to provide rapid soothing effects in potential pharmacological applications. Comparing the results of this study with other recent investigations, a good technological performance of clinoptilolite-rich rock can be inferred despite the relatively low zeolite content (˜56 wt.%).
- Published
- 2019
46. Molecular Characterization of Coxsackievirus B5 Isolates from Sewage, Italy 2016–2017
- Author
-
Gabriele Buttinelli, Concetta Amato, Paolo Castiglia, Stefano Fiore, Paola Stefanelli, Licia Veronesi, Simona De Grazia, Antonella Cicala, Angela Maria Vittoria Larocca, Andrea Cossu, Francesca Pennino, Silvia Spertini, Sabine Gamper, Giovanni M. Giammanco, Roberta Zoni, Stefano Fontana, Angelo Siragusa, Maria Triassi, Cinzia Germinario, Fontana, S., Fiore, S., Buttinelli, G., Amato, C., Veronesi, L., Zoni, R., Triassi, M., Pennino, F., Giammanco, G. M., De Grazia, S., Cicala, A., Siragusa, Danilo, Gamper, S., Spertini, S., Castiglia, P., Cossu, A., Germinario, C., Larocca, A. M. V., Stefanelli, P., Fontana, Stefano, Fiore, Stefano, Buttinelli, Gabriele, Amato, Concetta, Veronesi, Licia, Zoni, Roberta, Triassi, Maria, Pennino, Francesca, Giammanco, Giovanni Maurizio, De Grazia, Simona, Cicala, Antonella, Siragusa, Angelo, Gamper, Sabine, Spertini, Silvia, Castiglia, Paolo, Cossu, Andrea, Germinario, Cinzia, Larocca, Angela Maria Vittoria, and Stefanelli, Paola
- Subjects
0301 basic medicine ,Settore MED/07 - Microbiologia E Microbiologia Clinica ,Epidemiology ,Viral protein ,Health, Toxicology and Mutagenesis ,viruses ,030106 microbiology ,Sewage ,010501 environmental sciences ,Biology ,Coxsackievirus ,medicine.disease_cause ,Brief Communication ,01 natural sciences ,03 medical and health sciences ,Viral Proteins ,Phylogenetic analysi ,Non-polio enteroviruse ,Phylogenetics ,Virology ,medicine ,Phylogeny ,0105 earth and related environmental sciences ,Polioviruse ,Phylogenetic analysis ,CV-B5 ,Phylogenetic tree ,business.industry ,virus diseases ,Non-polio enteroviruses ,biology.organism_classification ,Enterovirus B, Human ,Italy ,GenBank ,Polioviruses ,Coxsackieviru ,business ,Food Science ,Environmental Monitoring - Abstract
Hereby, the partial Viral Protein 1 sequences of Coxsackievirus B5 (CV-B5) from sewage samples, collected in Italy from 2016 to 2017, were compared with those available in GenBank from clinical samples. Phylogenetic analysis highlighted: (I) the predominant circulation of CV-B5 genogroup B in Italy, and (II) the presence of two new sub-genogroups.
- Published
- 2019
47. The domus domini imperatoris Apicii built by Frederick II along the Ancient Via Appia (southern Italy): An example of damage diagnosis for a Medieval monument in rural environment
- Author
-
Francesco Izzo, Mariano Mercurio, Francesca Cilenti, Chiara Germinario, Celestino Grifa, Michele Gorrasi, Antonella Furno, Alessio Langella, Izzo, F., Furno, A., Cilenti, F., Germinario, C., Gorrasi, M., Mercurio, M., Langella, A., and Grifa, C.
- Subjects
History ,business.industry ,Brandi's theory ,Damage diagnosi ,0211 other engineering and technologies ,Ancient Via Appia ,020101 civil engineering ,02 engineering and technology ,Building and Construction ,Masonry ,Archaeology ,Rural environment ,0201 civil engineering ,Building archaeology ,Frederick II ,Mortar ,Biodeterioration ,021105 building & construction ,Medieval monument ,Building material ,General Materials Science ,business ,Civil and Structural Engineering - Abstract
A stratigraphic analysis applied to the architectural remains of the medieval domus Apicii (Calvi, Benevento) allowed to define four main building periods characterized by different materials and masonry techniques. Intense biological colonization and other damage pathologies affect the building geomaterials. A quantitative evaluation of the conservation state of the monument accounts for a moderate to a very severe damage, with a progressive damage index (DIprog) up to 3.3 value. The results of this multidisciplinary investigation represent an important starting point for an ethically acceptable making-decision process within a modern restoration and conservation of the monument.
- Published
- 2020
48. External reflectance FTIR dataset (4000–400 cm−1) for the identification of relevant mineralogical phases forming Cultural Heritage materials
- Author
-
Alessio Langella, Celestino Grifa, Chiara Germinario, Francesco Izzo, Mariano Mercurio, Izzo, F., Germinario, C., Grifa, C., Langella, A., and Mercurio, M.
- Subjects
Rocks ,Cultural Heritage material ,Optical anisotropy ,Kramers-Kronig transformation ,02 engineering and technology ,01 natural sciences ,010309 optics ,symbols.namesake ,0103 physical sciences ,Fourier transform infrared spectroscopy ,Mineral ,Remote sensing ,Analytical technique ,Organic compound ,021001 nanoscience & nanotechnology ,Condensed Matter Physics ,Reflectivity ,Atomic and Molecular Physics, and Optics ,Electronic, Optical and Magnetic Materials ,Characterization (materials science) ,Cultural heritage ,Identification (information) ,Fourier transform ,symbols ,0210 nano-technology ,Reflectance infrared spectroscopy ,Geology - Abstract
The use of vibrational spectroscopy is gaining more and more relevance in the field of the identification and characterization of Cultural Heritage materials. In this frame we propose and discuss a copious collection of Fourier Transform Infrared (FTIR) spectra acquired in external reflectance (ER) mode (4000–400 cm−1), which is a non-destructive and inexpensive analytical technique. Up to 192 spectra were collected, processed and made free-available to the scientists and professionals working in the Cultural Heritage sector. Color and inclusions, optical anisotropy, polymorphism and isomorphism, water content, crystallinity index, polyphasicity are some properties that have driven to rationale of the paper for discriminating groups of geomaterials usually found in studies aimed at the valorization and conservation of Cultural Heritage. Finally, this study offers a robust opportunity to beginners who intend to use ERFTIR as a tool in the field of qualitative and non-destructive mineralogical analysis.
- Published
- 2020
49. Removal of emerging contaminants from water by zeolite-rich composites: A first approach aiming at diclofenac and ketoprofen
- Author
-
Francesco Izzo, Mariano Mercurio, George E. Rottinghaus, Milica Spasojević, Aleksandra Daković, Bruno de Gennaro, Danijela Smiljanic, Chiara Germinario, Alessio Langella, Smiljanic, D., de Gennaro, B., Izzo, F., Langella, A., Dakovic, A., Germinario, C., Rottinghaus, G. E., Spasojevic, M., and Mercurio, M.
- Subjects
Cetylpyridinium chloride ,02 engineering and technology ,010402 general chemistry ,01 natural sciences ,Surface modified natural zeolites (SMNZs) ,symbols.namesake ,chemistry.chemical_compound ,Adsorption ,Zeta potential ,General Materials Science ,Composite material ,Zeolite ,Arquad® 2HT-75 ,Clinoptilolite ,Chemistry ,Surfactant stability ,Bilayer ,Langmuir adsorption model ,General Chemistry ,021001 nanoscience & nanotechnology ,Condensed Matter Physics ,0104 chemical sciences ,Mechanics of Materials ,symbols ,Water treatment ,0210 nano-technology - Abstract
In this study, composites of the natural zeolites and cationic surfactants cetylpyridinium chloride and Arquad® 2HT-75 were used for removal of two emerging contaminants – diclofenac sodium and ketoprofen. Modifying a clinoptilolite- and a phillipsite-rich tuff, with surfactants with one or two hydrophobic tails, resulted in composites in monolayer and bilayer forms. The intention was to better evaluate interactions of composites with selected molecules. Starting materials and composites were characterized by ATR–FTIR and STA coupled with EGA. The adsorption capacities of the prepared sorbents were estimated by determination of adsorption isotherms and kinetic runs. Maximum adsorption capacity, obtained from the Langmuir model, showed that the best results were for the bilayer form of the composites up to 35 mg/g. Between the two surfactants, composites with cetylpyridinium chloride gave better results. Zeta potential measurements showed that the surfactants turned out to be unstable on the zeolite surface, the only exception being bilayers prepared using the two-tailed surfactant Arquad® 2HT-75. These results suggested possible applications of these composites for water treatment purposes.
- Published
- 2020
50. Radiocarbon dating of mortars: Contamination effects and sample characterisation. The case-study of Andalusian medieval castles (Jaén, Spain)
- Author
-
Celestino Grifa, Irene Montilla Torres, Alessio Langella, Paola Ricci, Chiara Germinario, Mariaelena Fedi, Vicente Salvatierra Cuenca, Francesco Izzo, Mariano Mercurio, Carmine Lubritto, Lubritto, C., Ricci, P., Germinario, C., Izzo, F., Mercurio, M., Langella, A., Cuenca, V. S., Torres, I. M., Fedi, M., Grifa, C., Lubritto, Carmine, Ricci, Paola, Germinario, Chiara, Izzo, Francesco, Mercurio, Mariano, Langella, Alessio, Cuenca, Vicente Salvatierra, Torres, Irene Montilla, Fedi, Mariaelena, and Grifa, Celestino
- Subjects
Radiocarbon dating ,010506 paleontology ,Gypsum ,Sample (material) ,Geochemistry ,engineering.material ,01 natural sciences ,law.invention ,law ,0601 history and archaeology ,Andalusian castle ,Electrical and Electronic Engineering ,Instrumentation ,0105 earth and related environmental sciences ,Lime ,060102 archaeology ,Applied Mathematics ,06 humanities and the arts ,Contamination ,Condensed Matter Physics ,Mortar ,Igneous rock ,FTIR spectroscopy ,Age estimation ,engineering ,Geology - Abstract
Since 1960s, mortars have been exploited as a potential material for radiocarbon dating and, despite the fact that this methodology appears very simple in its principles, some measured radiocarbon ages were definitely different from the expected historic ages. The paper concerns to the characterisation of mortars from three Andalusian castles (Spain) by means of different mineralogical techniques in order to control “contamination effect” that could affect age estimation. Several mixtures of binders and aggregates composed the archaeological mortars; lime-based or gypsum-based binders were distinguished whereas the aggregates varied from carbonates to intrusive igneous rocks. The radiocarbon dating provided good results for lime-based mortars with silicate aggregate; conversely, for other specimens the method for sample preparation (Cryo2SoniC) was improved increasing the ultrasonic time and decreasing the mesh size. The research points out the importance of a multi-analytical approach aimed at improving a widely accepted protocol for 14C dating of archaeological mortars.
- Published
- 2018
Catalog
Discovery Service for Jio Institute Digital Library
For full access to our library's resources, please sign in.