43 results on '"Güneş, Yasemin"'
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2. Suratentorial Tümör Cerrahisinde %20 Mannitol ve %3 Hipertonik Salin Kullanımlarının Beyin Relaksasyonu, Hemodinamik Parametreler, Serum Osmolaritesi ve Elektrolitleri Üzerine Etkilerinin Değerlendirilmesi.
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Ermeydan, Buket, Biricik, Ebru, İlginel, Murat Türkeün, Tunay, Demet Lafli, and Güneş, Yasemin
- Abstract
Copyright of Journal of Anesthesia / Anestezi Dergisi (JARSS) is the property of Logos Medical Publishing and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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- 2024
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3. Effect of One-Lung Ventilation on Blood Sevoflurane and Desflurane Concentrations
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Biricik, Ebru, Karacaer, Feride, Güneş, Yasemin, Dağlıoğlu, Nebile, Efeoğlu, Pınar, Ilgınel, Murat, Avcı, Alper, and Özcengiz, Dilek
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- 2019
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4. İntrakraniyal Anevrizma Cerrahisi Sırasında Kan Akımının Geçici Olarak Durdurulması Yöntemleri.
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Güneş, Yasemin and Laflı Tunay, Demet
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ARTERIAL occlusions , *INTRACRANIAL aneurysm surgery , *SUBARACHNOID hemorrhage , *BLOOD flow , *CARDIAC arrest - Abstract
The only effective treatment for cerebral aneurysms, which have high morbidity and mortality rate, is endovascular or surgical repair. These interventions are used to treat subarachnoid hemorrhage (SAH) secondary to aneurysm, preventing further morbidity, as well as preventing SAH in aneurysms that have not yet ruptured. Surgical treatment of cerebral aneurysms, performed by placing a clip on the neck of the aneurysm using a microsurgical technique, is an effective and safe procedure, but it also involves certain difficulties. The clipping stage is very critical, especially in large aneurysms, close to critical cerebral and vascular structures, and deeply located. Risks associated with surgical aneurysm treatment include new or worsening neurological deficits caused by brain retraction, temporary arterial occlusion, and intraoperative bleeding. To reduce these risks, various methods have been described to temporarily stop or reduce blood flow during the clipping stage of the neck of the aneurysm. These include rapid ventricular pacing (RVP), deep hypothermic cardiac arrest (DHCA), and adenosine-induced hypotension and asystole. [ABSTRACT FROM AUTHOR]
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- 2024
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5. Anestezik Ajanlar ve Otoakustik Emisyonlar
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GÜNEŞ, Ceren, primary, BİRİCİK, Ebru, additional, TARKAN, Özgür, additional, and GÜNEŞ, Yasemin, additional
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- 2023
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6. Remifentanil–ketamine vs. propofol–ketamine for sedation in pediatric patients undergoing colonoscopy: A randomized clinical trial
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Karacaer, Feride, Biricik, Ebru, Ilgınel, Murat, Küçükbingöz, Çağatay, Ağın, Mehmet, Tümgör, Gökhan, Güneş, Yasemin, and Özcengiz, Dilek
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- 2018
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7. LOMBER MİKRODİSKEKTOMİ AMELİYATINDA AMELİYAT SONRASI HIZLANDIRILMIŞ İYİLEŞME (ERAS) PROTOKOLLERİNİN ETKİNLİĞİ
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ILGINEL, Murat Türkeün, primary, OKTAY, Kadir, additional, ÖZDEN, Özge, additional, LAFLI TUNAY, Demet, additional, BİRİCİK, Ebru, additional, KARACAER, Feride, additional, ÖZSOY, Mazhar, additional, ÇETİNALP, Nuri Eralp, additional, and GÜNEŞ, Yasemin, additional
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- 2023
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8. Covid 19 Pandemisi ve Deliryum
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BİRİCİK, Ebru, primary and GÜNEŞ, Yasemin, additional
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- 2022
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9. Effect of low thoracic erector spinae block on postoperative pain management in patients undergoing lumbar microdiscectomy surgery.
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Biricik, Ebru, Karacaer, Feride, Tunay, Demet Laflı, Ilgınel, Murat, Oktay, Kadir, Ünlügenç, Hakkı, and Güneş, Yasemin
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POSTOPERATIVE pain treatment ,INTRAVENOUS anesthesia ,DISCECTOMY ,ERECTOR spinae muscles ,PATIENT satisfaction ,SPINAL surgery ,POSTOPERATIVE pain - Abstract
Copyright of Cukurova Medical Journal / Çukurova Üniversitesi Tip Fakültesi Dergisi is the property of Cukurova University, Faculty of Medicine and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2023
- Full Text
- View/download PDF
10. Crafts and traditional professions in Edirne
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Güneş, Yasemin and Aksoy, Ömer
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Edirne ,Geleneğin dönüşü ,Zanaat ,Craft ,Return of tradition ,Traditional professions ,Geleneksel meslekler - Abstract
Edirne, günümüze kadar farklı kültürlerin asırlardır bir arada yaşadığı bir şehir olmuştur. Bu kültür çeşitliliği dolayısıyla Edirne toprakları günümüze kadar pek çok zanaat ve geleneksel mesleğin icra edildiği bir şehir olmuştur. Zanaat ve geleneksel meslekler dediğimiz kavramlar, bir topluluğun kültür aktarımına aracılık eden olgulardır. Toplulukların kültürel kodlarını aktardıkları, günlük yaşantıda kolaylıkla görebileceğimiz mekânlarda zanaatların ve ustasından çıraklarına aktarılması yıllar süren mesleklerin icra edildiğine şahit olmak mümkündür. Öncelikle araştırma amacımız; Edirne’de yaşatılmaya çalışılan zanaat ve geleneksel meslekleri icra eden kıymetli insanlara ulaşabilmek. Diğer bir amacımız; tespit edilen zanaat ve geleneksel meslekleri belirleyip yok olmasına imkân vermeden belirli yöntemler kullanarak kayıt altına alınmasıyla alanımıza katkı sağlamaktır. " Edirne’deki Zanaatlar ve Geleneksel Meslekler” adlı araştırmamızda Edirne’deki birer insan hazinesi olarak gördüğümüz her bir zanaatkâr ve ustanın icra ettiği eşsiz zanaat ve geleneksel meslekler yaptığımız araştırmalar ve derlemeler neticesinde tespit edilmiştir. Araştırmamız “Giriş”, “Sonuç” ve “Kaynaklar” haricinde üç bölümden oluşmaktadır. “Birinci Bölüm”, “Araştırma Alanı Hakkında Bilgi ve Literatür Taraması”, “İkinci Bölüm”, “Araştırma Konusu İle İlgili Genel Kavramlar ve Geleneğin Dönüşümü”, “Üçüncü Bölüm”, “Somut Olmayan Kültürel Miras Bağlamında Edirne’deki Zanaatlar ve Geleneksel Meslekler” olarak başlıklandırılmıştır. Edirne has been a city where different cultures have lived together for centuries until today. Due to this cultural diversity, the lands of Edirne have been a city where many crafts and traditional professions are practiced until today. The concepts we call crafts and traditional professions are the phenomena that mediate the cultural transfer of a community. It is possible to witness the practice of crafts and professions that take years to be transferred from master to apprentice in places where communities convey their cultural codes and which we can easily see in daily life. First of all, our research aim is; To reach the valuable people who practice the crafts and traditional professions that are tried to be kept alive in Edirne. Our other aim is; It is to contribute to our field by determining the crafts and traditional occupations and recording them using certain methods without allowing them to disappear. In our research called "Crafts and Traditional Professions in Edirne", the unique crafts and traditional professions performed by each artisan and master in Edirne, which we see as a human treasure, were determined as a result of our researches and compilations. "The First Part", "Information and Literature Review About the Research Area", "Second Part", "General Concepts Related to the Research Subject and Transformation of Tradition", "Third Part", "Edirne in the Context of Intangible Cultural Heritage" It is titled as “Crafts and Traditional Professions in Turkey”.
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- 2022
11. Nörocerrahi ve Eras (Enhanced Recovery After Surgery)
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BİRİCİK, Ebru, primary and GÜNEŞ, Yasemin, additional
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- 2020
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12. SEKİZİNCİ SINIF ÖĞRENCİLERİNİN DAİRE VE DAİRE DİLİMİNİN ALANI İLE İLGİLİ PROBLEM OLUŞTURMA BECERİLERİNİN İNCELENMESİ
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GÜNEŞ, Yasemin KATRANCI- Büşra KIRAL İlknur, primary
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- 2020
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13. Uyanık Kraniyotomide Anestezi Yaklaşımı: Olgu Sunumu
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Laflı Tunay, Demet, primary and Güneş, Yasemin, additional
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- 2020
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14. Comparison of effects of preemptive oral pregabalin-tramadol combination and paracetamol-tramadol combination administration on postoperative tramadol consumption
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ILGINEL, Murat Türkeün, primary, LAFLI TUNAY, Demet, additional, GÜNEŞ, Yasemin, additional, KARACAER, Feride, additional, BİRİCİK, Ebru, additional, and ILGINEL, Özge, additional
- Published
- 2019
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15. 60-72 ay çocuklarında matematik öğrenme güçlüğü kontrol listesinin geliştirilmesi
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Işık, Aybüke, Sinan, Betül, Güven, Büşra, Altuntaş, Edanur, Emekli, Esra, Ceylan, Gülnihal, Sinan, Hatice Kübra, Yılmaz, Havvanur, Aksu, Hilal, Erdem, Kübra, Tetik, Merve, Kapusuz, Mevhibe Şeyma, Karışan, Sultan, Kuzu, Sümeyra, Eryılmaz, Şeniz Naz, Demirkesen, Şeyma, Özkan, Şeymanur, Güneş,Yasemin, Çakır, Zehra Beyza, and Maltepe Üniversitesi, Eğitim Fakültesi
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Matematik ,Öğrenme güçlüğü ,Okul öncesi matematik ,Okul öncesi ,Matematik öğrenme güçlüğü - Abstract
Amaç: Okul öncesi dönemde matematik öğrenme güçlüğü olan öğrencilerin sayısı oldukça fazla olmasına rağmen matematik öğrenme güçlüğünün tespitinde kullanılacak ölçme araçları oldukça sınırlıdır. Bu araştırma amacı erken çocukluk döneminde Matematik Güçlüğü Kontrol Listesi geliştirmek, geçerlilik ve güvenirlik çalışmasını yapmaktır. Yöntem: Araştırma nicel araştırma yöntemlerinden tarama modeline girmektedir. Çalışma grubunu İstanbul ili Maltepe ve Ataşehir ilçeleri MEB’e bağlı 2 devlet anaokuluna devam eden 203 öğrenciden oluşmaktadır. Erken çocukluk dönemi matematik güçlüğü kontrol listesini oluşturmak amacıyla 67 madde oluşturulmuştur. Ölçme aracının kapsam geçerliğini sağlamak amacıyla uzman görüşü alınmıştır. Ayrıca yine kapsam geçerliği için Bracken Temel Kavram Ölçeği İfade Edici formu da uygulanmış ve bu iki ölçme aracı arasındaki ilişkiye bakılmıştır. Ölçme aracının güvenirliği ise Kuder-Richardson 20 ile test edilmiştir. Ayrıca öğrencilere cinsiyet, doğum tarihi, okul adı, sınıfı, anne/baba doğum tarihi, ebeveynlerin eğitim düzeyi, ebeveynlerin çalışma durumunu içeren bilgiler Öğrenci Bilgi Formu ile toplanmıştır. Verilerin istatistiksel analizi, Sosyal Bilimler için İstatistik Programı (SPSS) kullanılarak yapılmıştır.
- Published
- 2019
16. Pediatrik Nöroanestezide Sıvı Tedavisi
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Laflı Tunay, Demet, primary and Güneş, Yasemin, additional
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- 2019
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17. Anesthetic Management of Pediatric Craniofacial Surgery and Methods of Reducing Blood Loss
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BİRİCİK, Ebru and GÜNEŞ, Yasemin
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otologous transfusion ,lcsh:R5-920 ,Craniosynostosis,blood loss,erythropoietin,Tranexamic Acid,otologous transfusion ,Tranexamic Acid ,Craniosynostosis ,lcsh:R ,Kranisinostozis,kan kaybı,eritropoietin,traneksamik asit,otolog transfüzyon ,lcsh:Medicine ,blood loss ,erythropoietin ,lcsh:Medicine (General) - Abstract
One of the most common craniofacial congenital abnormalities requiring surgery is craniosynostosis where there is premature fusion of one or more cranial sutures. A thorough assessment of the airway is necessary to enable careful planning of the anesthetic technique for craniofacial surgery. Pediatric craniofacial reconstruction procedures, has been associated with significant morbidity including cardiac arrest, massive transfusion, coagulopathy, severe hypotension, air embolism, largely related to blood loss. Transfusion of homologous blood is associated with significant and well-known risks. Reported transfusion rates for pediatric patients undergoing surgical correction of synostotic calvarial sutures vary between 20 and 500% of estimated blood volume. Attempts at reducing exposure to allogeneic transfusions, using blood conservation techniques such as controlled hypotension and normovolemic hemodilution, have met with mixed results and are not always practical in small infants. In children undergoing surgical correction of craniosynostosis, pre-treated with erythropoietin, intraoperative tranexamic acid reduces transfusion requirement., Cerrahi gerektiren en yaygın kraniofasiyal konjenital amomalilerden biri olan kraniyosinostozis bir veya daha fazla kafa sütürünün erken füzyonudur. Kraniyofasiyal cerrahi için anestezik teknik planlanırken detaylı bir şekilde havayolunun değerlendirilmesi gereklidir. Pediatrik kraniofasiyal düzeltme işlemleri büyük ölçüde kan kaybına bağlı olarak kardiyak arrest, masif transfüzyon, koagülopati, şiddetli hipotansiyon, hava embolisi, dahil olmak üzere önemli morbiditeye sahiptir. Homolog kan transfüzyonu önemli ve iyi bilinen risklerle birliktedir. Sinostotik kalvaryal sütürde cerrahi düzeltme uygulanan pediyatrik hastalarda bildirilen transfüzyon oranları tahmini kan hacminin %20-%500’ ü arasında değişmektedir. Kontrollü hipotansiyon ve normovolemik hemodilüsyon gibi kan koruma teknikleri gibi allojenik transfüzyonu azaltma girişimlerinde karmaşık sonuçlar alınmıştır ve küçük bebeklerde uygulanması her zaman pratik değildir. Kraniyosinostozlarda cerrahi düzeltme yapılan çocuklarda, eritropoietin ile önceden tedavi, ameliyat sırasındaki traneksamid asit uygulaması transfüzyon gereksinimini azaltmaktadır.
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- 2015
18. Perioperative Management and Anesthesia in Epilepsy
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ILGINEL, Murat Türkeün, LAFLI TUNAY, Demet, and GÜNEŞ, Yasemin
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Anestezi,Epilepsi,ilaç etkileşimi ,Health Care Sciences and Services ,Anesthesia,drug interactions,epilepsy ,Sağlık Bilimleri ve Hizmetleri - Abstract
Epilepsi paroksismal, tekrarlayıcı nöbetlerle seyreden klinik bir hastalık olup popülasyonun önemli oranını etkiler; böylelikle epilepsili hastalar anestezi uygulamalarının önemli bir bileşenini oluşturmaktadır. Antiepileptik ajanların anestezi üzerine etkisi olabilecek birçok fizyolojik ve farmakolojik etkisi mevcuttur; bunun yanı sıra anestezik ajanların kendilerinin de nöbet aktivitesini modüle etme veya güçlendirme kapasitesi vardır. Bu derlemede epilepsili olguların perioperatif yönetiminde izlenecek planı; ayrıca güncel epilepsi cerrahisine özgü anestezik yaklaşımı ortaya koymayı amaçladık., Epilepsy, which is a paroxysmal clinical disease with recurring seizures, influences a significant proportion of the population. Thus epileptic patients constitute an important component of anesthesia practice. Antiepileptic agents have many physiological and pharmacological effects which may have an effect on anesthesia; and also the anesthetic agents themselves have the capacity to modulate or potentiate seizure activity. In this review, we aimed to reveal the plan of perioperative management of epileptic patients; and also the anesthetic approach specific to current epilepsy surgery.
- Published
- 2017
19. Effect of single dose of esmolol on response to endotracheal intubation and bispectral index during sevoflurane and desflurane anesthesia in patients over 65 years
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UÇAK, Dilek, GÜNEŞ, Yasemin, BİRİCİK, Ebru, ILGINEL, Murat, and Çukurova Üniversitesi
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Esmolol,endotrakeal entübasyon,BIS ,Esmolol ,Health Care Sciences and Services ,BIS ,Sağlık Bilimleri ve Hizmetleri ,endotrakeal entubasyon - Abstract
Purpose: In this prospective, randomized study, we aimed to compare the effects of single dose of esmolol on haemodynamic, bispectral index (BIS) changes related to intubation and recovery at sevoflurane and desflurane anaesthesia in 65 years and older patients who scheduled for elective surgeryMaterial and Methods: Eighty ASA II-III patients who undergo elective surgery were divided 4 groups. After standart and Bispectral monitoring to all patients, the first group received sevoflurane and salin,e second group received desflurane and salin. The patients in Group III received sevoflurane and single dose of esmolol(1 mg kg-1) and group IV received desflurane and single dose of esmolol(1 mg kg-1). While given induction drugs, neuromuscular blockers, during intubation and at 30 second, first minute and 5. minutes of intubation, oxygen saturation, systolic and diastolic blood pressure, heart rate, BIS values were recorded. Results: Single dose of esmolol administration during sevoflurane and desflurane anaesthesia was found to inhibit the increase of BIS values due to endotracheal intubation. When the groups compared, extubation, eye-opening and recovery time were significantly shorter in the groups which applied esmolol. Conclusion: In elderly patients, single dose esmolol administration in desflurane and sevoflurane anesthesia significantly inhibits sympathetic decharge and BIS value increases due to tracheal intubation., Amaç: Bu prospektif ve randomize çalışma, elektif cerrahi geçirecek 65 yaş ve üzeri ASA II-III hastalarda, sevofluran ve desfluran anestezisinde tek doz uygulanacak esmololün hemodinamik değişiklikler, entübasyona bağlı Bispektral indeks (BIS) değişiklikleri ve derlenme üzerine etkilerini karşılaştırmayı amaçlamaktadır. Gereç ve Yöntem: 65 yaş üzeri ASA II-III elektif cerrahi geçirecek 80 hasta 4 gruba ayrıldı. Tüm hastalara standart monitörizasyon ve BIS monitörizasyonu uygulandıktan sonra Grup I deki hastalara sevofluran ve intravenöz(IV) salin, Grup II deki hastalara desfluran ve IV salin, Grup III deki hastalara sevofluran ve tek doz esmolol (1 mg kg-1), Grup IV deki hastalara desfluran ve tek doz esmolol (1 mg kg-1) uygulandı. Hastaların indüksiyon ajan uygulanması sonrası, esmolol uygulanması sonrası, kas gevşetici uygulanması sonrası, entübasyon esnasında, entübasyon sonrası oksijen saturasyonu, sistolik kan basıncı, diyastolik kan basıncı, kalp atım hızı ve bispektral indeks değerleri kaydedildi. Bulgular: Tek doz esmolol uygulamasının sevofluran ve desfluran anestezisinde endotrakeal entübasyona bağlı BIS değerlerindeki artışı engellediği görüldü. Gruplar karşılaştırıldığında esmolol uygulanan gruplarda ekstübasyon, göz açma ve derlenme süreleri daha kısa bulundu. Sonuç: İleri yaş grubu hastalarda desfluran ve sevofluran anestezisinde tek doz uygulanan esmolol trakeal entübasyona yanıt olarak gelişen sempatik deşarjı ve BİS değerlerindeki artışı baskılamaktadır.
- Published
- 2017
20. Preemptif oral tramadol-pregabalin ile tramadol-parasetamol kombinasyonunun postoperatif tramadol tüketimi üzerine etkilerinin karşılaştırılması.
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Ilgınel, Murat Türkeün, Tunay, Demet Laflı, Güneş, Yasemin, Karacaer, Feride, Biricik, Ebru, Ilgınel, Özge, and Cüneyitoğlu, Şule
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POSTOPERATIVE pain ,BREAST surgery ,DRUG side effects ,CONTROL groups ,BREAST - Abstract
Copyright of Cukurova Medical Journal / Çukurova Üniversitesi Tip Fakültesi Dergisi is the property of Cukurova University, Faculty of Medicine and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2019
- Full Text
- View/download PDF
21. Remifentanil–cetamina vs. propofol–cetamina para sedação em pacientes pediátricos submetidos à colonoscopia: ensaio clínico randômico
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Karacaer, Feride, primary, Biricik, Ebru, additional, Ilgınel, Murat, additional, Küçükbingöz, Çağatay, additional, Ağın, Mehmet, additional, Tümgör, Gökhan, additional, Güneş, Yasemin, additional, and Özcengiz, Dilek, additional
- Published
- 2018
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22. Laparoskopik kolesistektomi cerrahisi geçiren hastalarda neostigmin ve sugammadeks uygulamasının postoperatif bulantı kusma üzerine etkilerinin karşılaştırılması
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Özbilen, Fisun, primary, Karacaer, Feride, additional, Hatipoğlu, Zehra, additional, Özalevli, Mehmet, additional, and Güneş, Yasemin, additional
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- 2018
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23. Perioperative Management and Anesthesia in Epilepsy
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ILGINEL, Murat Türkeün, primary, LAFLI TUNAY, Demet, additional, and GÜNEŞ, Yasemin, additional
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- 2018
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24. Comparison of lidocaine-lidocaine and lidocaine-esmolol efficiency in control of haemodynamic response to endotracheal extubation craniotomies
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SÜMER, Evin, primary, BİRİCİK, Ebru, additional, GÜNEŞ, Yasemin, additional, GÜNDÜZ, Murat, additional, and ILGINEL, Murat, additional
- Published
- 2018
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25. Akromegalili olguda gelişen postoperatif ciddi hipertansiyon
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Ilgınel, Murat Türkeün, primary, Güneş, Yasemin, additional, Çetinalp, Nuri Eralp, additional, Karadayı, Baha Sinan, additional, Aslanbaş, Özcan, additional, and Ünlügenç, Hakkı, additional
- Published
- 2017
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26. Altmışbeş yaş üzeri hastalarda tek doz esmolol’ün desfluran ve sevofluran anestezisinde trakeal entübasyona yanıt ve bispektral indeks üzerine etkisi
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Uçak, Dilek ,, primary, Güneş, Yasemin, additional, Biricik, Ebru, additional, and Ilgınel, Murat, additional
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- 2017
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27. Comparison of the cardioprotective effects of dexmedetomidineand remifentanil in cardiac surgery*
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TÜRKTAN, Mediha, primary, GÜNEŞ, Yasemin, additional, YALINIZ, Hafize, additional, MATYAR, Selçuk, additional, HATİPOĞLU, Zehra, additional, GÜLEÇ, Ersel, additional, GÖÇEN, Uğur, additional, and ATALAY, Atakan, additional
- Published
- 2017
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28. Comparison of incidence and risk factors of delirium between general and regional anesthesia in elderly patients after lower extremity surgery
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Küpeli, İlke, Güleç, Ersel, Biricik, Ebru, Biçer, Ömer, and Güneş, Yasemin
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mental disorders ,behavioral disciplines and activities ,nervous system diseases - Abstract
Purpose: The aim of this study is to compare the risk factors and the incidence of delirium following orthopedic surgery under the general or regional anesthesia in elderly patients.Material and Methods: One hundred twenty elderly patients aged ≥65 years scheduled for total hip or knee arthroplasty and femur fracture surgery were enrolled into the study. Patients were allocated into two groups to receive regional anesthesia (group R, n=50) or general anesthesia (group G, n=70). Hemodynamic and blood parameters, potential risk factors of delirium including age, sex, duration of surgery, the type of anesthesia, coexisting disease, smoking and amount of drug used delirium tests (Confusion Assessment Method, Delirium Rating Scale-Revised-98), hospital stay and costs were recorded for all patients.Results: Demographic data, duration of surgery, preoperative and postoperative hemodynamic and laboratory parameters were similar in two groups. Delirium incidence was 12.5% for all patients. We found delirium in six patients (8.6%) of group G and nine patients (18%) of group R. The most important risk factors were advanced age and polypharmacy for all patients. Hospital stay and cost were associated with severity of delirium.Conclusion: We found that the incidence of delirium is 12.5% in elderly patients undergoing total hip or knee arthroplasty and femur fracture surgery. Advanced age and polypharmacy are risk factors of delirium. Delirium increases the hospital stay and cost., Amaç: Bu çalışmada; ortopedik cerrahi geçiren yaşlı hastalarda genel anestezi veya rejyonel anestezi sonrası görülen deliryum insidanslarının ve risk faktörlerinin karşılaştırılması amaçlanmıştır.Gereç ve Yöntem: Total kalça protezi, total diz protezi, femur kırığı cerrahisi geçiren, 65 yaş üzeri toplam 120 hastada gerçekleştirildi. Genel anestezi (n: 70) veya rejyonel anestezi (n:50) uygulanmasına göre iki gruba ayrıldı. Tüm hastaların, hemodinamik ve kan parametreleri, yaş, cinsiyet, ameliyat süresi, anestezi tipi, eşlik eden hastalıklar, sigara ve kullanılan ilaç miktarı gibi deliryumun potansiyel risk faktörleri, deliryum testleri (Confusion Assessment Method, Delirium Rating Scale-Revised-98), hastanede kalış süreleri ve maliyetleri kaydedildi.Bulgular: demografik veriler, operasyon zamanı, preoperatif ve postoperatif hemodinamik ve laboratuar değerleri her iki grupta aynıydı. Tüm hastalar için deliryum insidansı %12.5 idi. Grup G’de 6 hastada (%8.6), grup R’de 9 hastada (%18) deliryum görüldü. En önemli risk faktörlerinin ileri yaş ve polifarmasi olduğu saptandı. Ağır deliryum görülen hastalarda hastanede yatış süresi ve maliyet yüksekti.Sonuç: bu çalışma total kalça- diz artroplastisi, femur kırığı cerrahisi geçiren yaşlı hastaların %12.5’unda deliryum geliştiğini göstermiştir. Deliryum insidansı rejyonel veya genel anestezi ile değişiklik göstermedi. İleri yaş ve polifarmasi deliryum için risk faktörleridir. Deliryum hastane maliyeti ve hastanede yatış süresini artırır.
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- 2015
29. Nociceptive Effects of Locally Treated Metoprolol
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ÇUKADAR, Nursima, BARAN, Furkan, ÖZSOY, Kadir, UYANIK, Fatih, SÜRER, Tuba, MERT, Tufan, GÜNEŞ, Yasemin, and Çukurova Üniversitesi
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Metoprolol,İntraplantar,Hiperaljezi,Allodini,Sıçan ,lcsh:R5-920 ,Hyperalgesia ,Intraplantar ,lcsh:R ,lcsh:Medicine ,rat ,lcsh:Medicine (General) ,Allodynia ,Metoprolol - Abstract
Purpose: Beta (β-)-adrenergic receptor antagonists, such as metoprolol, are often used to avoid circulatory complications during anesthesia for their antihypertensive and anti-tachycardia effects in patients with cardiovascular diseases. Although a few previous studies have been reported to exert antinociceptive and anesthetic effects of these drugs, knowledge about their action mechanisms in nociceptive process including pain perception is limited. This study therefore designed to identify the roles underlying the probable anti or hyper nociceptive effects of metoprolol, a β- adrenergic receptor antagonist. In addition, effects of metoprolol were compared the dobutamin, a β-adrenergic agonist. Material and Methods: To investigate the effects of β-adrenergic receptor blocker, metoprolol, sensor functions using thermal plantar test (hyperalgesia) and dynamic plantar aesthesiometer (allodynia) techniques were examined in the rats after local (intraplantar) injection to paws. Results: Metoprolol, an antagonist, significantly decreased the thermal latency and mechanical thresholds with dose and time dependent manner. However, dobutamine, an agonist, enhanced the latency and thresholds dose and time dependent. Conclusions: This results suggest that ın contrast to dobutamine, locally treated metoprolol may cause hyperalgesic and allodynic actions. In addition, our results can demonstrate that peripheral β-adrenergic receptors can play important roles in nociceptive process, Amaç: Beta (β)-adrenerjik reseptör antagonisti olan metoprolol, antihipertansif ve antitaşikardik etkileri nedeniyle kardiyovasküler sistem hastalığı olan kişilerde anestezi sırasında dolaşım sistemi komplikasyonları önlemek için kullanılmaktadır. Sistemik metoprolol’un antinosiseptif ve anestezik etkileri sahip olduğunu gösteren birkaç çalışma olmasına rağmen, ağrı algısını da içeren nosiseptif süreçlerindeki etkilerine ilişkin bilgi oldukça sınırlıdır. Bu nedenle bu çalışma bir β--adrenerjik reseptör antagonisti olan metoprolol’un lokal uygulama sonrası muhtemel anti nosiseptif veya hiper nosiseptif etkilerini belirlemek için planlandı. Metoprolol bulguları β--adrenerjik reseptör agonisti dobutaminle karşılaştırıldı. Materyal ve Metod: Lokal (intraplantar) olarak uygulanan metoprololun etkileri, duysal fonksiyon testleri olan termal plantar test ve mekanik plantar test teknikleri kullanılarak araştırıldı. Bulgular: Antagonist metoprolol termal latansı ve mekanik eşiği doza ve zamana bağlı olarak anlamlı bir şeklide azalttı. Bununla beraber, agonist dobutamin, metoprololun aksine latans ve eşik parametrelerini doz ve zaman bağlı olarak arttırdı. Araştırma Makalesi / Research Article 258 Cilt/Volume 40 Yıl/Year 2015 Metoprolol- Nosiseptif Etkileri Sonuç: Bulgular lokal olarak uygulanan metoprolol’un hiperaljezi ve allodini oluşturabileceğini göstermektedir. Metoprolol ve dobutamin kullanılarak elde edilen veriler, periferik β-adrenerjik reseptörlerin nosiseptif süreçte önemli roller oynayabileceğini işaret etmektedir
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- 2015
30. Comparison of incidence and risk factors of delirium between general and regional anesthesia in elderly patients after lower extremity surgery
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Küpeli, İlke, primary, Güleç, Ersel, additional, Biricik, Ebru, additional, Biçer, Ömer Sunkar, additional, and Güneş, Yasemin, additional
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- 2016
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31. Kraniyotomilerde endotrakeal ekstübasyona bağlı gelişen hemodinamik yanıtın kontrolünde lidokain-lidokain ve lidokain - esmolol etkinliğinin karşılaştırılması.
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Sümer, Evin, Biricik, Ebru, Güneş, Yasemin, Gündüz, Murat, and Ilgınel, Murat
- Abstract
Copyright of Cukurova Medical Journal / Çukurova Üniversitesi Tip Fakültesi Dergisi is the property of Cukurova University, Faculty of Medicine and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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- 2018
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32. Epilepside Perioperatif Yönetim ve Anestezi.
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Ilgınel, Murat Türkeün, Tunay, Demet Laflı, and Güneş, Yasemin
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Copyright of Archives Medical Review Journal / Arsiv Kaynak Tarama Dergisi is the property of Cukurova University, Faculty of Medicine and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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- 2018
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33. Lokal Metoprolol Uygulamasının Nosiseptif Etkileri
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Çukadar, Nursima, primary, Baran, Furkan, additional, Özsoy, Kadir Ercan, additional, Uyanık, Fatih, additional, Sürer, Tuba, additional, Mert, Tufan, additional, and Güneş, Yasemin, additional
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- 2015
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34. Pediyatrik Kraniofasiyal Cerrahide Anestezik Yaklaşım ve Kan Kaybını Azaltan Yöntemler
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Biricik, Ebru, primary and Güneş, Yasemin, additional
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- 2015
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35. Comparison of the cardioprotective effects of dexmedetomidine and remifentanil in cardiac surgery.
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TÜRKTAN, Mediha, GÜNEŞ, Yasemin, YALINIZ, Hafize, MATYAR, Selçuk, HATİPOĞLU, Zehra, GÜLEÇ, Ersel, GÖÇEN, Uğur, and ATALAY, Atakan
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- *
CARDIAC surgery , *CARDIOTONIC agents , *DEXMEDETOMIDINE , *CORONARY artery bypass , *REMIFENTANIL , *BIOMARKERS - Abstract
Background/aim: Myocardial protection is an important factor of open heart surgery and biological biomarkers (lactate, CKMB, cardiac troponin I, and pyruvate) are used to assess myocardial damage. This study compares the effects of dexmedetomidine and remifentanil on myocardial protection during coronary artery bypass grafting (CABG) surgery. Materials and methods: Patients scheduled for elective CABG surgery (n = 60) were included in this study. Anesthesia induction was introduced with propofol, fentanyl, and vecuronium bromide. Anesthesia was maintained with remifentanil infusion and sevoflurane in the remifentanil group (Group R) and with dexmedetomidine infusion and sevoflurane in the dexmedetomidine group (Group D). Blood samples for biochemical markers were taken from the coronary sinus catheter before cardiopulmonary bypass (T1), 20 min after aortic cross-clamping (T2), 20 min after removal of the aortic cross-clamping (T3), and 10 min after separation from cardiopulmonary bypass (T4). Results: Demographic data were similar between the groups. Lactate level at the T2 period and CKMB levels during the study period were lower in Group D than in Group R. In both groups, all values except pyruvate significantly increased over time. Conclusion: The dexmedetomidine-sevoflurane combination may improve the cardioprotective effect in comparison with remifentanilsevoflurane in CABG surgery. [ABSTRACT FROM AUTHOR]
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- 2017
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36. Elektrokonvülzif Tedavi Anestezisinde Ketamin, Tiyopental, Ketamin-Tiyopental Kombinasyonunun Depresyon Üzerine Etkisi.
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Kuşçu, Özlem Özkan, Karacaer, Feride, Biricik, Ebru, Güleç, Ersel, Tamam, Lut, and Güneş, Yasemin
- Abstract
Copyright of Turkish Journal of Anesthesia & Reanimation is the property of Turkish Society of Anaesthesiology & Reanimation and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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- 2015
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37. Vitamin D ve Anestezi.
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Biricik, Ebru and Güneş, Yasemin
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Vitamin D is a vitamin not only associated with calcium-phosphorus metabolism but also affects many organ systems. Because of its effect on the immune system in recent years, it has attracted much attention. Vitamin D deficiency is a clinical condition that can be widely observed in the society. Thus, patients with vitamin D deficiency are often seen in anaesthesia practice. In the absence of vitamin D, prolongation of intensive care unit stay, increase in mortality and morbidity and also association of chronic diseases further increase the importance of vitamin D deficiency. The results obtained from studies have led to the question of whether poor surgical outcome is associated with vitamin D deficiency. We assessed the vitamin D deficiency and its negative consequences for the anaesthesiologist. [ABSTRACT FROM AUTHOR]
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- 2015
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38. Preeklamptik Gebelerde İntravenöz Magnezyum Sülfat Tedavisinin Bupivakain ile Oluşturulan Spinal Anesteziye Etkisi.
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Atçı, Mustafa, Ünlügenç, Hakkı, Güneş, Yasemin, Burgut, Refik, Işık, Geylan, Hatipoğlu, Zehra, and Türktan, Mediha
- Abstract
Copyright of Turkish Journal of Anesthesia & Reanimation is the property of Turkish Society of Anaesthesiology & Reanimation and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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- 2015
- Full Text
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39. Laparoskopik kolesistektomi cerrahisi geçiren hastalarda neostigmin ve sugammadeks uygulamasının postoperatif bulantı kusma üzerine etkilerinin karşılaştırılması
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Özbilen, Fisun, Güneş, Yasemin, and Anesteziyoloji ve Reanimasyon Anabilim Dalı
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Anestezi ve Reanimasyon ,Anesthesiology and Reanimation - Abstract
ÖZETLaparoskopik Kolesistektomi Cerrahisi Geçiren Hastalarda Neostigmin ve Sugammadeks Uygulamasının Postoperatif Bulantı Kusma Üzerine Etkilerinin KarşılaştırılmasıAmaç: Bu çalışmada laporaskopik kolesistektomi yapılan hastalarda sugammadeks ve neostigmin uygulamasının postoperatif bulantı kusma üzerine etkilerinin karşılaştırılması. Gereç ve Yöntem: Bu çalışma, Çukurova Üniversitesi Tıp Fakültesi Anesteziyoloji ve Reanimasyon Anabilim Dalı ve Etik Kurul onayı ile hastalardan bilgilendirilmiş onam formu alınarak gerçekleştirildi. ASA I-III statüsünde olan, öngörülen cerrahi süresi 150 dakikayı aşmayan, APFEL Skoruna göre %40 ın üzerinde olan 60 hasta çalışmaya dahil edildi . Basit rasgele yöntemle randomize edilen hastalar iki gruba ayrıldı. Birinci grup neostigmin grubu (Grup I), ikinci grup sugammadeks grubu (Grup II). Premedike olmayan olgular operasyon odasına alındığında rutin kalp atım hızi non invaziv sistolik ve diyastolik kan basınçları ve periferik oksijen satürasyonları monitorize edildi. Anestezi indüksiyonunda tüm hastalara tiyopental 5-7 mg/kg, rokuronyum 0,5 mg/kg intravenöz olarak uygulanarak endotrakeal entübasyon gerçekleştirldi. Oksijen (%33) + azot protoksit (%67) +desfluran ile anestezi idamesi sağlandı. Postop analjezik olarak 1,5 mg/kg tramadol uygulandı. Anestezi uygulamasının sonlandırılmasında son cilt dikişi atılırken iki grupta da desfluran ve N2O kesilerek %100 oksijene geçildi. Eş zamanlı olarak kas gevşeticiyi antagonize etmek için grup I'e neostigmin,grup II'ye sugammadeks uygulandı. Ekstübasyon ve derlenme süresi, bulantı ve kusma ile diğer yan olası yan etkiler değerlendirildi. Bulgular: Grupların demografik verileri birbirine benzerdi. Postoperatif esktübasyon ve derlenme süresi sugammadeks grubunda nesotigmin grubundan daha kısa idi. Postoperatif bulantı ve kusam ilk 30 dakikada sugammadeks grubunda nesotigmin grubundan daha az olmasına rağmen istaistiksel olarak anlamlı değildi. Sonuç: Bulantı ve kusma riski yüksek olgularda desfluran ile oluşturulan genel anestezide dekürarizasyon amacıyla neostigmin ya da sugammadeks uygulamasının bulantı kusma açısından birbirlerine üstünlükleri olmadığı kanısına varıldı. Anahtar Kelimeler: Tiyopental, roküronyum, desfluran, neostigmin, sugamadeks bulantı kusma ABSTRACTComparison of Neostigmine and Sugammadex for Postoperative Nausea and VomitingPurpose: The aim of this study is to compare the effects of neostigmine and sugammadex on the postoperative nausea and vomiting in patients undergoing laparoscopic cholecystectomy sugery. Materials and Methods: This study is accomplished after obtaining informed consent forms from patients and with the approvals of the Ethics Committee and the Anesthesiology and Reanimation Department of the Cukurova University Medical Faculty. 60 patients having an ASA status between 1 to 3 and with a predicted operation time not exceeding 150 minutes were included to the study. Patients randomized with simple indiscriminate methodology were divided into two groups. The firstgroup received neostigmin(Group I), the second group received sugammadeks (Group II) respectively.On arrival in the operating room, routine monitors were applied to the unpremedicated patients for recording HR, non invasive systolic blood pressures (SBP), diastolic blood pressures (DBP), peripheral oxygen saturation (SpO2). For anesthesia induction, all patients were applied thiopental (5-7 mg/kg) and rocuronium (0.5 mg/kg) intravenously and endotracheal entubation was provided. After tracheal intubation, the lungs were ventilated with an N2O/oxygen mixture (FiO2 0.5) and anesthesia was maintained with desflurane. All patients applied tramadol(1,5 mg/kg) for postoperative analgesia. After completion of the surgery, cessation of desflurane and N2O while the last skin sutures were closured and neuromuscular blockade was reversed with atropine and neostigmine or sugammadeks. Extubation time and recover time, postoperative hemodynamic variables and the other advers effects were recorded. Results: Demographic variables were similar in groups. Extübation and recovery times were shorter in group sugammadex than in group neostigmine. Postoperative nausea an vomiting was lower in sugammadex group than neostigmine group at first thirty minutes, but this diffference was not istatistically significant.Conclusion: It is concluded that when neostigmine or sugammadex were applied for decurarization after general anesthesia with desflurane there is no superiority between sugammadeks or neostigmine for postoperative nausea and vomitingKey Words: Tiyopental ,roküronyum,desflurane, neostigmine, sugammadex 71
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- 2015
40. Pediatrik olgularda rokuronyum enjeksiyon ağrısının azaltılmasında rokuronyum uygulama hızı ve remifentanilin etkisi
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Şimşek Ülkü, Hatice, Güneş, Yasemin, and Anesteziyoloji ve Reanimasyon Anabilim Dalı
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Remifentanil ,Anestezi ve Reanimasyon ,Pain ,Anesthesiology and Reanimation ,Rocuronium ,Children ,Injections - Abstract
Amaç: Çalışmamızda pediatrik olgularda yavaş ve hızlı rokuronyumenjeksiyonu öncesi uygulanan remifentanilin hemodinamik değişiklikler ve rokuronyumenjeksiyon ağrısı üzerine olan etkisinin plasebo ile karşılaştırılması hedeflendi.Gereç ve Yöntem: Çalışmamıza genel anestezi altında elektif cerrahiplanalanan, yaşları 5-15 yaş arasında, ASA - grubu 120 pediatrik hasta alındı.Premedikasyon yapılmayan hastalar operasyon odasına alınıp rutin monitorize edildi.Tüm hastalarda anestezi indüksiyonu % 2,5 tiyopental (5 mg/kg) ile gerçekleştirildi.Ardından rokuronyum enjeksiyonu (0.6 mg/kg) yapıldı. Hastalara rokuronyumenjeksiyonu sonrasında anestezi idamesinde % 50 O2+ % 50 azot protoksit+ desfluran(% 6) başlandı. Olgular rastgele 4 gruba ayrılarak; Grup A'ya rokuronyum yavaşenjeksiyon- salin, Grup B'ye rokuronyum (0.6 mg/kg IV) yavaş enjeksiyonuremifentanil,Grup C'ye rokuronyum hızlı enjeksiyonu-salin, Grup D'ye rokuronyumhızlı enjeksiyonu-remifentanil uygulandı. Rokuronyum yavaş enjeksiyonu 1dk'da,rokuronyum hızlı enjeksiyonu 5sn'de yapıldı. Rokuronyum enjeksiyonu sırasındahastaların çekme yanıtları 0-3 puanlı çekme yanıt skoruna göre kaydedildi. Preoperatif,anestezi indüksiyonu öncesi ve sonrası, rokuronyum enjeksiyonu sonrası, entübasyonsonrası 1. ve 3.dk'da, ekstübasyon ve postoperatif dönemde SAB, DAB, KAH'ları veO2 saturasyonu takip edildi.Bulgular: Grupların demografik verileri birbirine benzerdi (p>0,05). SKB, DKBve SpO2 ölçümleri karşılaştırıldığında dört grup arasında bir fark saptanmadı.Remifentanil yapılan gruplarda (Grup B ve D'de sırasıyla p: 0,0001;101,4±22,1, p:0,003; 99,8±18,3), plasebo yapılan gruplara (Grup A ve C'de sırasıyla p:0,025;107,4±21,7 , p: 0,012; 114,0±16,4) göre KAH rokuronyum enjeksiyonu sonrası 1.dk'dadaha düşük bulundu. Hastaların çekme yanıt skorları incelendiğinde yanıtsızlık oranınınen yüksek olduğu gruplar B (% 66,7) ve D grupları (% 70) idi. Yanıt olmayan hastasayısı A ve C gruplarında 9 iken, remifentanil uygulanan B grubunda 20, D grubunda21 idi. Jenarilize yani tüm vucütta olan yanıt ise en çok A (% 20, n=6) ve C (% 20, n=6)gruplarında görüldü.Sonuç: Pediyatrik olgularda rokuronyuma bağlı gelişen enjeksiyon ağrısındaenjeksiyon hızının etkisinin olmadığı, rokuronyum öncesi yapılan remifentanilin ciddihemodinamik deişikliklere yol açmaksızın enjeksiyon ağrısını enjeksiyon hızı ileilişkisiz olarak önemli oranda azalttığı kanısına varıldı.Anahtar Kelimeler: Rokuronyum, enjeksiyon ağrısı, pediyatrik hasta, hızlıenjeksiyon, yavaş enjeksiyon, remifentanil Aim: In the present study, we aimed to determine the effect of remifentaniladministration prior to slow and fast rocuronium injektion on hemodynamic changesand rocuronium injection pain, compared with placebo, in pediatric patients.Methods: 120 5-15-year-old and American Society of Anesthesiologists (ASA)score I/II pediatric patients who scheduled for elective surgery under general anesthesiaincluded in the study. Patients those without premedication were routinely monitored inthe operation room. Anesthesia was induced with intravenous 2.5% thiopental sodium(5 mg/kg) followed by 0.6 mg per kg of rocuronium administration to all patients. Afterrocuronium injection, anesthesia was maintained with the combination of 50% O2 and50% nitrogen protoxide and 6% desflurane. Patients were randomly allocated into fourgroups: group A: slow rocuronium injection-saline; group B: slow rocuronium injection(0.6 mg/kg IV)- remifentanyl; group C: fast rocuronium injection-saline; group D: fastrocuronium injection- remifentanyl. Slow and fast rocuronium administration wasperformed within one minute and five seconds, respectively. Withdrawal movementafter rocuronium injection was recorded based on a 3-point response to withdrawalscore. Systolic (SBP) and diastolic blood pressure (DBP), heart rate (HR) and oxygensaturation (OS) was recorded before and after anesthesia induction, after rocuroniuminjection, first and third minutes after tracheal intubation, and during extubation andpostoperative period.Results: The demographic data were comparable among all groups (p>0,05).There were no statistically significant differences in SBP, DBP and OS baseline valuesamong four groups. One minutes after rocuronium injection, HR values were found tobe lower in remifentanil groups (p:0,0001; 101,4±22,1, p:0,003; 99,8±18,3 in group Band D, respectively) compared with placebo groups (p:0,025; 107,4±21,7 , p: 0,012;114,0±16,4 in group A and C, respectively). With respect to response to withdrawalscores, unresponsiveness rates were the highest in group B (%66,7) and group D (%70).The number of non-responder patients was 9 in saline-administered groups (group Aand C), whereas it was 20 and 21 in remifentanil-administered groups (group B and D,respectively). Generalized responses were observed predominantly in group A (20%)and C (20%). The number of patients with generalized response was highest in group A(20%, n=6) and C (20%, n=6).Conclusion: There was no impact of infusion speed on rocuronium injectionpain in pediatric cases, whereas it is concluded that remefentanil administration prior torocuronium injection considerably reduced rocuronium injection pain regardlessinjection speed and without serious hemodynamic changes.Keywords: Rocuronium; injection pain, fast injection, slow injection,pediatric patients, remifentanil. 61
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- 2015
41. [Effect of rocuronium administration rate and remifentanil on prevention of rocuronium injection pain in pediatric cases].
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Şimşek Ülkü H, Güneş Y, Ilgınel M, Biricik E, and Karacaer F
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- Adolescent, Child, Child, Preschool, Drug Administration Schedule, Female, Humans, Injections, Intravenous adverse effects, Male, Pain Measurement, Remifentanil, Rocuronium, Treatment Outcome, Analgesics, Opioid administration & dosage, Androstanols administration & dosage, Anesthesia, General, Neuromuscular Nondepolarizing Agents administration & dosage, Piperidines administration & dosage
- Abstract
Objectives: In this study, we aimed to determine the effect of remifentanil administration prior to slow and fast rocuronium infusion on hemodynamic changes and rocuronium injection pain in pediatric patients., Methods: In total, 120 5-15-year-old ASA score I/II pediatric patients were included in the study. Group A: slow rocuronium injection-saline; group B: slow rocuronium injection (0.6 mg/kg IV)-remifentanyl; group C: fast rocuronium injection-saline; and group D: fast rocuronium injection-remifentanyl. Withdrawal movement after rocuronium injection was recorded based on a 3-point response to withdrawal score. Hemodynamic parameters were recorded., Results: One minute after rocuronium injection, HR values were found to be lower in remifentanil groups (p: 0.0001; 101.4±22.1, p: 0.003; 99.8±18.3 in group B and D, respectively) compared with those in placebo groups (p: 0.025; 107.4±21.7, p: 0.012; 114.0±16.4 in group A and C, respectively). With respect to the response to withdrawal scores, unresponsiveness rates were the highest in group B (66.7%) and group D (70%). The number of non-responder patients was 9 in saline-administered groups (group A and C), whereas it was 20 and 21 in remifentanil-administered groups (group B and D, respectively). Generalized responses were observed predominantly in groups A (20%) and C (20%). Generalized responses were highest in groups A (20%, n=6) and C (20%, n=6)., Conclusion: There was no impact of infusion speed on rocuronium injection pain in pediatric cases, whereas it is concluded that remifentanil administration prior to rocuronium injection considerably reduced rocuronium injection pain regardless of injection speed and without serious hemodynamic changes.
- Published
- 2017
- Full Text
- View/download PDF
42. Effect of Ketamine, Thiopental and Ketamine-Thiopental Combination during Electroconvulsive Therapy for Depression.
- Author
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Kuşçu ÖÖ, Karacaer F, Biricik E, Güleç E, Tamam L, and Güneş Y
- Abstract
Objective: We aimed to evaluate the effect of anaesthesia with thiopental (4 mg kg(-1)), ketamine (1 mg kg(-1)) and ketamine-thiopental (1 mg kg(-1) and 4 mg kg(-1), respectively) combination during electroconvulsive therapy (ECT) on the Hamilton Depression Rating Scale (HDRS) and Hamilton Anxiety Rating Scale (HAM-A) and haemodynamic variables in patients with resistant major depression., Methods: Patients with HDRS scores above 17 were included. The patients were randomly divided into three groups according to the anaesthesia used. Group 1 was given thiopental (4 mg kg(-1)), Group 2 was given ketamine (1 mg kg(-1)) and Group 3 was given ketamine (1 mg kg(-1)) and thiopental (4 mg kg(-1)). Succinylcholine (1 mg kg(-1)) was administered in all patients for muscle relaxation. HDRS and HAM-A scores were evaluated before ECT, after 3, 6. ECT and after the final ECT. Systolic and diastolic blood pressures, heart rates and oxygen saturations were recorded before and after anaesthesia induction and after the ECT procedure. Seizure duration was recorded., Results: Fifty-eight patients were included in the study. Thirty (52%) patients were male and 28 (48%) were female. The mean age was 42.7±15.8 years in Group 1, 44.8±11 years in Group 2 and 38.6±6.8 years in Group 3. In all groups, HDRS scores were reduced compared with the baseline values. There was no statistical significant difference between the groups regarding HDRS scores. HAM-A scores were higher in Group 2 and Group 3. Systolic and diastolic blood pressures and heart rate values were lower in Group 1 and the difference was statistically significant., Conclusion: In this study, anaesthesia induced with thiopental, ketamine and thiopental-ketamine combination was observed to not result in a difference in ECT for patients with treatment-resistant depression. Ketamine at a dose of 1 mg kg(-1) given just before ECT did not enhance the antidepressant effect of ECT; however, anxiety scores were increased with ketamine application.
- Published
- 2015
- Full Text
- View/download PDF
43. The Effect of Intravenous Magnesium Sulphate Treatment on the Spinal Anaesthesia Produced by Bupivacaine in Pre-eclamptic Patients.
- Author
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Atçı M, Ünlügenç H, Güneş Y, Burgut R, Işık G, Hatipoğlu Z, and Türktan M
- Abstract
Objective: In our study, the effect of intravenous magnesium sulphate in normal and pre-eclamptic patients on spinal anaesthesia produced by bupivacaine was investigated., Methods: Sixty-four pregnant (32 normal and 32 pre-eclamptic) were accepted in this study. Pregnants were divided into four groups as patients given intravenous magnesium sulphate and as control. Spinal anaesthesia was induced with 12.5 mg 0.5% hyperbaric bupivacaine. Intraoperative and postoperative haemodynamic variables, sensorial block periods, onset times of sensorial and motor block, maximum sensorial block levels, the time to reach maximum block level, Bromage scores, consumptions of intraoperative analgesic and ephedrine, the quality of anaesthesia, the duration of spinal anaesthesia and magnesium levels in blood and cerebrospinal fluid were measured and recorded., Results: The level of magnesium in blood and cerebrospinal fluid was significantly higher in the group given magnesium in pre-eclamptic patients (p<0.01). Onset of sensory block times were significantly longer in intravenous magnesium group than in groups 1, 2 and 3 (p<0.05). Onset of motor block times were significantly longer and the duration of anaesthesia was shorter in groups given magnesium (p<0.05). Although the quality of anaesthesia was similar, supplemental analgesic consumption was significantly higher in pre-eclamptic pregnants given magnesium sulphate than in pre-eclamptic pregnants who were not given magnesium sulphate (p<0.05)., Conclusion: Intravenous magnesium sulphate treatment during the spinal anaesthesia produced by bupivacaine extended the onset of sensory and motor block times, shortened the duration of spinal anaesthesia and therefore led to early analgesic requirement.
- Published
- 2015
- Full Text
- View/download PDF
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