190 results on '"Fusco, Domenico"'
Search Results
2. Radiological assessment of dementia: the Italian inter-society consensus for a practical and clinically oriented guide to image acquisition, evaluation, and reporting
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Pizzini, Francesca B., Conti, Enrico, Bianchetti, Angelo, Splendiani, Alessandra, Fusco, Domenico, Caranci, Ferdinando, Bozzao, Alessandro, Landi, Francesco, Gandolfo, Nicoletta, Farina, Lisa, Miele, Vittorio, Trabucchi, Marco, Frisoni, Giovanni B., and Bastianello, Stefano
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- 2022
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3. Characteristics of patients with cancer in European long-term care facilities
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Villani, Emanuele Rocco, Fusco, Domenico, Franza, Laura, Onder, Graziano, Bernabei, Roberto, and Colloca, Giuseppe Ferdinando
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- 2022
- Full Text
- View/download PDF
4. What about the caregiver? A journey into Parkinson’s disease following the burden tracks
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Lo Monaco, Maria Rita, Di Stasio, Enrico, Ricciardi, Diego, Solito, Marcella, Petracca, Martina, Fusco, Domenico, Onder, Graziano, Landi, Giovanni, Zuccalà, Giuseppe, Liperoti, Rosa, Cipriani, Maria Camilla, Brisi, Caterina, Bernabei, Roberto, Silveri, Maria Caterina, and Bentivoglio, Anna Rita
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- 2021
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5. Cognitive decline in older long-term survivors from Non-Hodgkin Lymphoma: a multicenter cross-sectional study
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La Carpia, Domenico, Liperoti, Rosa, Guglielmo, Mauro, Di Capua, Beatrice, Devizzi, Liliana Franca, Matteucci, Paola, Farina, Lucia, Fusco, Domenico, Colloca, Giuseppe, Di Pede, Patricia, Ferrara, Marianna Luciana, Hohaus, Stephan, Bernabei, Roberto, and Ripamonti, Carla Ida
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- 2020
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6. Prevalence of Obsessive-Compulsive Symptoms in Elderly Parkinson Disease Patients: A Case-Control Study
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Lo Monaco, Maria Rita, Di Stasio, Enrico, Zuccalà, Giuseppe, Petracca, Martina, Genovese, Danilo, Fusco, Domenico, Silveri, Maria Caterina, Liperoti, Rosa, Ricciardi, Diego, Cipriani, Maria Camilla, Laudisio, Alice, and Bentivoglio, Anna Rita
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- 2020
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7. Safinamide as an adjunct therapy in older patients with Parkinson’s disease: a retrospective study
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Lo Monaco, Maria Rita, Petracca, Martina, Vetrano, Davide Liborio, Di Stasio, Enrico, Fusco, Domenico, Ricciardi, Diego, Laudisio, Alice, Zuccalà, Giuseppe, Onder, Graziano, and Bentivoglio, Anna Rita
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- 2020
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8. Untangling the relationship between fat distribution, nutritional status and Parkinson’s disease severity
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Pisciotta, Maria S., Fusco, Domenico, Grande, Giulia, Brandi, Vincenzo, Lo Monaco, Maria R., Laudisio, Alice, Onder, Graziano, Bentivoglio, Anna R., Ricciardi, Diego, Bernabei, Roberto, Zuccalà, Giuseppe, and Vetrano, Davide L.
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- 2020
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9. Balancing the risks and benefits of antipsychotic medications for symptom management in older patients with cancer
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Liperoti, Rosa, Fusco, Domenico, Cipriani, Maria C., Lo Monaco, Maria R., and Onder, Graziano
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- 2018
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10. Sarcopenia Diagnosis and Management in Hematological Malignancies and Differences with Cachexia and Frailty
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Colloca, Giuseppe Ferdinando, primary, Bellieni, Andrea, additional, Di Capua, Beatrice, additional, Iervolino, Marialuisa, additional, Bracci, Serena, additional, Fusco, Domenico, additional, Tagliaferri, Luca, additional, Landi, Francesco, additional, and Valentini, Vincenzo, additional
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- 2023
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11. Sarcopenia in Parkinson Disease: Comparison of Different Criteria and Association With Disease Severity
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Vetrano, Davide L., Pisciotta, Maria S., Laudisio, Alice, Lo Monaco, Maria R., Onder, Graziano, Brandi, Vincenzo, Fusco, Domenico, Di Capua, Beatrice, Ricciardi, Diego, Bernabei, Roberto, and Zuccalà, Giuseppe
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- 2018
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12. Frailty modifies the effect of polypharmacy and multimorbidity on the risk of death among nursing home residents: Results from the SHELTER study
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Zazzara, Maria Beatrice, Villani, Emanuele Rocco, Palmer, Katie, Fialova, Daniela, Corsonello, Andrea, Soraci, Luca, Fusco, Domenico, Cipriani, Maria Camilla, Denkinger, Michael, Onder, Graziano, Liperoti, Rosa, Onder, Graziano (ORCID:0000-0003-3400-4491), Liperoti, Rosa (ORCID:0000-0003-3740-1687), Zazzara, Maria Beatrice, Villani, Emanuele Rocco, Palmer, Katie, Fialova, Daniela, Corsonello, Andrea, Soraci, Luca, Fusco, Domenico, Cipriani, Maria Camilla, Denkinger, Michael, Onder, Graziano, Liperoti, Rosa, Onder, Graziano (ORCID:0000-0003-3400-4491), and Liperoti, Rosa (ORCID:0000-0003-3740-1687)
- Abstract
BackgroundFrailty, disability, and polypharmacy are prevalent in nursing home (NH) residents, often co-occurring with multimorbidity. There may be a complex interplay among them in terms of outcomes such as mortality. Aims of the study were to (i) assess whether nursing home residents with polypharmacy (5-9 medications) or hyperpolypharmacy (>= 10 drugs), have an increased risk of death and (ii) whether any association is modified by the co-presence of frailty or disability. MethodsCohort study with longitudinal mortality data including 4,023 residents from 50 European and 7 Israeli NH facilities (mean age = 83.6 years, 73.2% female) in The Services and Health for Elderly in Long Term care (SHELTER) cohort study. Participants were evaluated with the interRAI-LongTerm Care assessment tool. Frailty was evaluated with the FRAIL-NH scale. Hazard ratio (HR) of death over 12 months was assessed with stratified Cox proportional hazards models adjusted for demographics, facilities, and cognitive status. Results1,042 (25.9%) participants were not on polypharmacy, 49.8% (n = 2,002) were on polypharmacy, and 24.3% (n = 979) on hyperpolypharmacy. Frailty and disability mostly increased risk of death in the study population (frailty: HR = 1.85, 95%CI 1.49-2.28; disability: HR = 2.10, 95%CI 1.86-2.47). Among non-frail participants, multimorbidity (HR = 1.34, 95%CI = 1.01-1.82) and hyperpolypharmacy (HR = 1.61, 95%CI = 1.09-2.40) were associated with higher risk of death. Among frail participants, no other factors were associated with mortality. Polypharmacy and multimorbidity were not associated with mortality after stratification for disability. ConclusionsFrailty and disability are the strongest predictors of death in NH residents. Multimorbidity and hyperpolypharmacy increase mortality only in people without frailty. These findings may be relevant to identify patients who could benefit from tailored deprescription.
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- 2023
13. Biological and Functional Biomarkers of Aging: Definition, Characteristics, and How They Can Impact Everyday Cancer Treatment
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Colloca, Giuseppe, Di Capua, Beatrice, Bellieni, Andrea, Fusco, Domenico, Ciciarello, Francesca, Tagliaferri, Luca, Valentini, Vincenzo, and Balducci, Lodovico
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- 2020
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14. Frailty modifies the effect of polypharmacy and multimorbidity on the risk of death among nursing home residents: Results from the SHELTER study
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Zazzara, Maria Beatrice, primary, Villani, Emanuele Rocco, additional, Palmer, Katie, additional, Fialova, Daniela, additional, Corsonello, Andrea, additional, Soraci, Luca, additional, Fusco, Domenico, additional, Cipriani, Maria Camilla, additional, Denkinger, Michael, additional, Onder, Graziano, additional, and Liperoti, Rosa, additional
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- 2023
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15. The Geriatrician: The Frontline Specialist in the Treatment of COVID-19 Patients
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Landi, Francesco, Barillaro, Christian, Bellieni, Andrea, Brandi, Vincenzo, Carfi, Angelo, Cipriani, Maria Camilla, D'Angelo, Emanuela, Falsiroli, Cinzia, Fusco, Domenico, Landi, Giovanni, Liperoti, Rosa, Lo Monaco, Maria Rita, Martone, Anna Maria, Marzetti, Emanuele, Pagano, Francesco Cosimo, Pais, Cristina, Russo, Andrea, Salini, Sara, Tosasto, Matteo, Tummolo, Anna Maria, Benvenuto, Francesca, Bramato, Giulia, Catalano, Lucia, Ciciarello, Francesca, Martis, Ilaria, Rocchi, Sara, Rota, Elisabetta, Salerno, Andrea, Tritto, Marcello, Sgadari, Antonio, Zuccàla, Giuseppe, and Bernabei, Roberto
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- 2020
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16. Rapidly Progressive Malignant Pelvic Perivascular Epithelioid Cell Neoplasm (PEComa) Associated with Eggerthella lenta Bloodstream Infection
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Cacciatore, Stefano, primary, Recupero, Carla, additional, Massaro, Claudia, additional, Elmi, Daniele, additional, Fusco, Domenico, additional, Badiali, Vanessa, additional, Brandi, Vincenzo, additional, Arciuolo, Damiano, additional, Marazzi, Fabio, additional, and Landi, Francesco, additional
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- 2022
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17. Association of depressive symptoms with circadian blood pressure alterations in Parkinson’s disease
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Vetrano, Davide L., Pisciotta, Maria S., Lo Monaco, Maria R., Onder, Graziano, Laudisio, Alice, Brandi, Vincenzo, La Carpia, Domenico, Guglielmo, Mauro, Nacchia, Antonio, Fusco, Domenico, Ricciardi, Diego, Bentivoglio, Anna R., Bernabei, Roberto, and Zuccalà, Giuseppe
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- 2015
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18. Myelodysplasia
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Fusco, Domenico, primary, Bellieni, Andrea, additional, Di Capua, Beatrice, additional, and Colloca, Giuseppe, additional
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- 2022
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19. Mirroring Emotions: Patients' Versus Caregivers' Perceptions of Sexual Experience in Parkinson's Disease
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Landi, Giovanni, primary, Monaco, Maria Rita Lo, additional, Stasio, Enrico Di, additional, Ricciardi, Diego, additional, Solito, Marcella, additional, Petracca, Martina, additional, Fusco, Domenico, additional, Rota, Elisabetta, additional, Salerno, Andrea, additional, Pagano, Francesco, additional, Liperoti, Rosa, additional, Bentivoglio, Anna Rita, additional, and Siveri, Maria Caterina, additional
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- 2021
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20. Age-Related Variations of Muscle Mass, Strength, and Physical Performance in Community-Dwellers: Results From the Milan EXPO Survey
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Landi, Francesco, Calvani, Riccardo, Tosato, Matteo, Martone, Anna Maria, Fusco, Domenico, Sisto, Alex, Ortolani, Elena, Savera, Giulia, Salini, Sara, and Marzetti, Emanuele
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- 2017
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21. Characteristics of patients with cancer in European long-term care facilities
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Villani, Emanuele Rocco, primary, Fusco, Domenico, additional, Franza, Laura, additional, Onder, Graziano, additional, Bernabei, Roberto, additional, and Colloca, Giuseppe Ferdinando, additional
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- 2021
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22. Subacute onset dystonia in a woman affected by Parkinson's disease following SARS-COV-2 infection
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Lo Monaco, Maria Rita, Bentivoglio, Anna Rita, Fusco, Domenico, Calabresi, Paolo, Piano, Carla, Lo Monaco, Maria Rita (ORCID:0000-0002-1457-7981), Bentivoglio, Anna Rita (ORCID:0000-0002-9663-095X), Calabresi, Paolo (ORCID:0000-0003-0326-5509), Lo Monaco, Maria Rita, Bentivoglio, Anna Rita, Fusco, Domenico, Calabresi, Paolo, Piano, Carla, Lo Monaco, Maria Rita (ORCID:0000-0002-1457-7981), Bentivoglio, Anna Rita (ORCID:0000-0002-9663-095X), and Calabresi, Paolo (ORCID:0000-0003-0326-5509)
- Abstract
N/A
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- 2021
23. Should face masks be worn to contain the spread of COVID-19 in the postlockdown phase?
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Landi, Francesco, Marzetti, Emanuele, Sanguinetti, Maurizio, Ciciarello, Francesca, Tritto, Marcello, Benvenuto, Francesca, Bramato, Giulia, Brandi, Vincenzo, Carfì, Angelo, D'Angelo, Emanuela, Fusco, Domenico, Lo Monaco, Maria Rita, Martone, Anna Maria, Pagano, Francesco Cosimo, Rocchi, Sara, Rota, Elisabetta, Russo, Andrea, Salerno, Andrea Maria, Cattani Franchi, Paola, Marchetti, Simona, Bernabei, Roberto, Landi, Francesco (ORCID:0000-0002-3472-1389), Marzetti, Emanuele (ORCID:0000-0001-9567-6983), Sanguinetti, Maurizio (ORCID:0000-0002-9780-7059), Lo Monaco, Maria Rita (ORCID:0000-0002-1457-7981), Pagano, Francesco, Salerno, Andrea, Cattani, Paola (ORCID:0000-0003-4678-4763), Bernabei On Behalf Of The Gemelli Against Covid-Geriatric Team, Roberto (ORCID:0000-0002-9197-004X), Landi, Francesco, Marzetti, Emanuele, Sanguinetti, Maurizio, Ciciarello, Francesca, Tritto, Marcello, Benvenuto, Francesca, Bramato, Giulia, Brandi, Vincenzo, Carfì, Angelo, D'Angelo, Emanuela, Fusco, Domenico, Lo Monaco, Maria Rita, Martone, Anna Maria, Pagano, Francesco Cosimo, Rocchi, Sara, Rota, Elisabetta, Russo, Andrea, Salerno, Andrea Maria, Cattani Franchi, Paola, Marchetti, Simona, Bernabei, Roberto, Landi, Francesco (ORCID:0000-0002-3472-1389), Marzetti, Emanuele (ORCID:0000-0001-9567-6983), Sanguinetti, Maurizio (ORCID:0000-0002-9780-7059), Lo Monaco, Maria Rita (ORCID:0000-0002-1457-7981), Pagano, Francesco, Salerno, Andrea, Cattani, Paola (ORCID:0000-0003-4678-4763), and Bernabei On Behalf Of The Gemelli Against Covid-Geriatric Team, Roberto (ORCID:0000-0002-9197-004X)
- Abstract
Background: In East Asia, face masks are commonly worn to reduce viral spread. In Euope and North America, however, their use has been stigmatised for a long time, although this view has radically changed during the ongoing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic. Notwithstanding this, it is still unclear whether face masks worn by COVID-19 carriers may indeed prevent viral transmission and environmental contamination. The objective of this study was to evaluate the effectiveness of surgical face masks in filtering SARS-CoV-2.Methods: Four male patients with COVID-19 were recruited for the study. Two patients wore a surgical mask for 5 h, while two others did not. The spread of the virus in the environment was evaluated through the approved Allplex 2019-nCoV assay.Results: In the room with the two patients without surgical masks, the swab performed on the headboard and sides of the beds was positive for SARS-CoV-2 contamination. In the other room, where two patients were wearing surgical masks, all of the swabs obtained after 5 h tested negative.Conclusions: The results of the current study add to the growing body of literature supporting the use of face masks as a measure to contain the spread of SARS-CoV-2 by retaining potentially contagious droplets that can infect other people and/or contaminate surfaces. Based on the current evidence, face masks should therefore be considered a useful and low-cost device in addition to social distancing and hand hygiene during the postlockdown phase.
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- 2021
24. Different impact of definitions of sarcopenia in defining frailty status in a population of older women with early breast cancer
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Bellieni, Agnese, Fusco, Domenico, Sanchez, A. M., Franceschini, Gianluca, Di Capua, B., Allocca, E., Di Stasio, Enrico, Marazzi, Fabio, Tagliaferri, Luca, Masetti, Riccardo, Bernabei, Roberto, Colloca, Giuseppe Ferdinando, Bellieni A., Fusco D., Franceschini G. (ORCID:0000-0002-2950-3395), Di Stasio E. (ORCID:0000-0003-1047-4261), Marazzi F., Tagliaferri L. (ORCID:0000-0003-2308-0982), Masetti R. (ORCID:0000-0002-7520-9111), Bernabei R. (ORCID:0000-0002-9197-004X), Colloca G. F., Bellieni, Agnese, Fusco, Domenico, Sanchez, A. M., Franceschini, Gianluca, Di Capua, B., Allocca, E., Di Stasio, Enrico, Marazzi, Fabio, Tagliaferri, Luca, Masetti, Riccardo, Bernabei, Roberto, Colloca, Giuseppe Ferdinando, Bellieni A., Fusco D., Franceschini G. (ORCID:0000-0002-2950-3395), Di Stasio E. (ORCID:0000-0003-1047-4261), Marazzi F., Tagliaferri L. (ORCID:0000-0003-2308-0982), Masetti R. (ORCID:0000-0002-7520-9111), Bernabei R. (ORCID:0000-0002-9197-004X), and Colloca G. F.
- Abstract
Sarcopenia is a geriatric syndrome characterized by losses of quantity and quality of skeletal muscle, which is associated with negative outcomes in older adults and in cancer patients. Different definitions of sarcopenia have been used, with quantitative data more frequently used in oncology, while functional measures have been advocated in the geriatric literature. Little is known about the correlation between frailty status as assessed by comprehensive geriatric assessment (CGA) and sarcopenia in cancer patients. We retrospectively analyzed data from 96 older women with early breast cancer who underwent CGAs and Dual X-ray Absorptiometry (DXA) scans for muscle mass assessment before cancer treatment at a single cancer center from 2016 to 2019 to explore the correlation between frailty status as assessed by CGA and sarcopenia using different definitions. Based on the results of the CGA, 35 patients (36.5%) were defined as frail. Using DXA Appendicular Skeletal Mass (ASM) or the Skeletal Muscle Index (SMI=ASM/heightˆ2), 41 patients were found to be sarcopenic (42.7%), with no significant difference in prevalence between frail and nonfrail subjects. Using the European Working Group on Sarcopenia in Older People (EWGSOP2) definition of sarcopenia (where both muscle function and mass are required), 58 patients were classified as “probably” sarcopenic; among these, 25 were sarcopenic and 17 “severely” sarcopenic. Only 13 patients satisfied both the requirements for being defined as sarcopenic and frail. Grade 3-4 treatment-related toxicities (according to Common Terminology Criteria for Adverse Events) were more common in sarcopenic and frail sarcopenic patients. Our data support the use of a definition of sarcopenia that includes both quantitative and functional data in order to identify frail patients who need tailored treatment.
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- 2021
25. Gender may be related to the side of the motor syndrome and cognition in idiopathic Parkinson's disease
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Bentivoglio, Anna Rita, Lo Monaco, Maria Rita, Liperoti, Rosa, Fusco, Domenico, Di Stasio, Enrico, Tondinelli, A., Marzullo, D., Maino, Alessandro, Cipriani, Maria Camilla, Silveri, Maria Caterina, Bentivoglio A. R. (ORCID:0000-0002-9663-095X), Lo Monaco M. R. (ORCID:0000-0002-1457-7981), Liperoti R. (ORCID:0000-0003-3740-1687), Fusco D., Di Stasio E. (ORCID:0000-0003-1047-4261), Maino A., Cipriani M. C., Silveri M. C. (ORCID:0000-0001-5012-0682), Bentivoglio, Anna Rita, Lo Monaco, Maria Rita, Liperoti, Rosa, Fusco, Domenico, Di Stasio, Enrico, Tondinelli, A., Marzullo, D., Maino, Alessandro, Cipriani, Maria Camilla, Silveri, Maria Caterina, Bentivoglio A. R. (ORCID:0000-0002-9663-095X), Lo Monaco M. R. (ORCID:0000-0002-1457-7981), Liperoti R. (ORCID:0000-0003-3740-1687), Fusco D., Di Stasio E. (ORCID:0000-0003-1047-4261), Maino A., Cipriani M. C., and Silveri M. C. (ORCID:0000-0001-5012-0682)
- Abstract
Background: and Sex and cognitive profile may be related to the laterality of motor symptoms in idiopathic Parkinson's disease. Introduction: Parkinson's disease (PD) is well recognised as an inherently asymmetric disease with unilateral onset of motor symptoms. The laterality of motor symptoms may be linked to sex, clinical and demographic variables, and neuropsychological disorders. However, the available data are inconsistent. This study aimed to explore the potential association between the laterality of motor symptoms and clinical and demographic variables and deficits in specific cognitive domains. Material and methods: We retrospectively recruited 97 participants with idiopathic PD without dementia; 60 presented motor symptoms on the left side and 37 on the right side. Both groups were comparable in terms of age, age at disease onset, disease duration, and severity of the neurological deficits according to the Unified Parkinson's Disease Rating Scale and the Hoehn and Yahr scale. Results: Participants with left-side motor symptoms scored lower on the Schwab and England Activities of Daily Living scale. Our sample included more men than women (67% vs. 33%). Both sexes were not equally represented in the 2 groups: there were significantly more men than women in the group of patients with left-side motor symptoms (77% vs. 23%), whereas the percentages of men and women in the group of patients with right-side motor symptoms were similar (51% vs. 49%). Both groups performed similarly in all neuropsychological tasks, but women, independently of laterality, performed better than men in the naming task. Conclusion: We found a clear prevalence of men in the group of patients with left-side motor symptoms; this group also scored lower on the Schwab and England Scale. Female sex was predictive of better performance in the naming task. Sex should always be considered in disorders that cause asymmetric involvement of the brain, such as PD.
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- 2021
26. Perspectives and limits of cancer treatment in an oldest old population
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Di Capua, B., Bellieni, A., Fusco, Domenico, Gambacorta, Maria Antonietta, Tagliaferri, Luca, Villani, Emanuele Rocco, Bernabei, Roberto, Valentini, Vincenzo, Colloca, Giuseppe Ferdinando, Fusco D., Gambacorta M. A. (ORCID:0000-0001-5455-8737), Tagliaferri L. (ORCID:0000-0003-2308-0982), Villani E. R., Bernabei R. (ORCID:0000-0002-9197-004X), Valentini V. (ORCID:0000-0003-4637-6487), Colloca G. F., Di Capua, B., Bellieni, A., Fusco, Domenico, Gambacorta, Maria Antonietta, Tagliaferri, Luca, Villani, Emanuele Rocco, Bernabei, Roberto, Valentini, Vincenzo, Colloca, Giuseppe Ferdinando, Fusco D., Gambacorta M. A. (ORCID:0000-0001-5455-8737), Tagliaferri L. (ORCID:0000-0003-2308-0982), Villani E. R., Bernabei R. (ORCID:0000-0002-9197-004X), Valentini V. (ORCID:0000-0003-4637-6487), and Colloca G. F.
- Abstract
Background: Population of oldest old will grow dramatically in the next future and cancer, physiologically related to aging, will be very prevalent among them. Lack of evidence is a huge problem to manage cancer in oldest old and will be more and more in the next years. Aims: Our purpose was to investigate the characteristics of a population of oldest old patients with cancer treated in the Radiation Oncology Unit of Fondazione Policlinico A. Gemelli IRCCS. Methods: We conducted a retrospective study. The primary outcome was to evaluate which characteristics of the population could influence the choice of oncological treatment (with radical or non-radical intent). Results: We identified a total of 348 patients: 140 were on follow-up; 177 were under treatment; 31 were considered not eligible for treatments. Patients under treatment had a high comorbidity index (mean Charlson Comorbidity Index 5.4), and a high prevalence of polypharmacy (mean number of drugs 5.6). More than half (53.1%) was treated with radical intent. Patients treated with radical intent were 1 year younger (87.1 years old vs 88.1 years old), more performant (ECOG 0.7 vs 1.3), and had less prevalence of metastatic neoplasia (6.4% vs 34.9%); comorbidities and drugs did not show differences in the two groups. Conclusion: Oldest old, usually not considered in international guidelines, are treated for oncological disease, often with radical intent. The treatment seems not to be tailored considering comorbidities but on performance status.
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- 2021
27. Different Impact of Definitions of Sarcopenia in Defining Frailty Status in a Population of Older Women with Early Breast Cancer. J Pers Med. 11(4):243. PMID: 33810556
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Biellini, A, Fusco, Domenico, Sanchez, Am, Franceschini, Gianluca, Di Capua, B, Allocca, E, Di Stasio, Enrico, Marazzi, Fabio, Tagliaferri, Luca, Masetti, Riccardo, Bernabei, Roberto, Colloca, Giuseppe Ferdinando, Fusco D, Franceschini G (ORCID:0000-0002-2950-3395), Di Stasio E (ORCID:0000-0003-1047-4261), Marazzi F, Tagliaferri L (ORCID:0000-0003-2308-0982), Masetti R (ORCID:0000-0002-7520-9111), Bernabei R (ORCID:0000-0002-9197-004X), Colloca GF., Biellini, A, Fusco, Domenico, Sanchez, Am, Franceschini, Gianluca, Di Capua, B, Allocca, E, Di Stasio, Enrico, Marazzi, Fabio, Tagliaferri, Luca, Masetti, Riccardo, Bernabei, Roberto, Colloca, Giuseppe Ferdinando, Fusco D, Franceschini G (ORCID:0000-0002-2950-3395), Di Stasio E (ORCID:0000-0003-1047-4261), Marazzi F, Tagliaferri L (ORCID:0000-0003-2308-0982), Masetti R (ORCID:0000-0002-7520-9111), Bernabei R (ORCID:0000-0002-9197-004X), and Colloca GF.
- Abstract
Sarcopenia is a geriatric syndrome characterized by losses of quantity and quality of skeletal muscle, which is associated with negative outcomes in older adults and in cancer patients. Different definitions of sarcopenia have been used, with quantitative data more frequently used in oncology, while functional measures have been advocated in the geriatric literature. Little is known about the correlation between frailty status as assessed by comprehensive geriatric assessment (CGA) and sarcopenia in cancer patients. We retrospectively analyzed data from 96 older women with early breast cancer who underwent CGAs and Dual X-ray Absorptiometry (DXA) scans for muscle mass assessment before cancer treatment at a single cancer center from 2016 to 2019 to explore the correlation between frailty status as assessed by CGA and sarcopenia using different definitions. Based on the results of the CGA, 35 patients (36.5%) were defined as frail. Using DXA Appendicular Skeletal Mass (ASM) or the Skeletal Muscle Index (SMI=ASM/heightˆ2), 41 patients were found to be sarcopenic (42.7%), with no significant difference in prevalence between frail and nonfrail subjects. Using the European Working Group on Sarcopenia in Older People (EWGSOP2) definition of sarcopenia (where both muscle function and mass are required), 58 patients were classified as “probably” sarcopenic; among these, 25 were sarcopenic and 17 “severely” sarcopenic. Only 13 patients satisfied both the requirements for being defined as sarcopenic and frail. Grade 3-4 treatment-related toxicities (according to Common Terminology Criteria for Adverse Events) were more common in sarcopenic and frail sarcopenic patients. Our data support the use of a definition of sarcopenia that includes both quantitative and functional data in order to identify frail patients who need tailored treatment.
- Published
- 2021
28. Gender may be related to the side of the motorsyndrome and cognition in idiopathic Parkinson’sdisease
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Bentivoglio, Anna Rita, Lo Monaco, Maria Rita, Liperoti, Rosa, Fusco, Domenico, Di Stasio, Enrico, Tondinelli, A, Maino, A, Marzullo, D, Cipriani, Maria Camilla, Silveri, Maria Caterina, Bentivoglio AR (ORCID:0000-0002-9663-095X), Lo Monaco MR (ORCID:0000-0002-1457-7981), Liperoti R (ORCID:0000-0003-3740-1687), Fusco D, Di Stasio E (ORCID:0000-0003-1047-4261), Cipriani MC, Silveri MC (ORCID:0000-0001-5012-0682), Bentivoglio, Anna Rita, Lo Monaco, Maria Rita, Liperoti, Rosa, Fusco, Domenico, Di Stasio, Enrico, Tondinelli, A, Maino, A, Marzullo, D, Cipriani, Maria Camilla, Silveri, Maria Caterina, Bentivoglio AR (ORCID:0000-0002-9663-095X), Lo Monaco MR (ORCID:0000-0002-1457-7981), Liperoti R (ORCID:0000-0003-3740-1687), Fusco D, Di Stasio E (ORCID:0000-0003-1047-4261), Cipriani MC, and Silveri MC (ORCID:0000-0001-5012-0682)
- Abstract
Parkinson's disease s a well recognised
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- 2021
29. COVID-19 and intestinal inflammation: Role of fecal calprotectin
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Abbate, Valeria, Acampora, Nicola, Addolorato, Giovanni, Agostini, Fabiana, Ainora, Maria Elena, Akacha, Karim, Amato, Elena, Andreani, Francesca, Andriollo, Gloria, Annetta, Maria Giuseppina, Annicchiarico, Brigida Eleonora, Antonelli, Mariangela, Antonucci, Gabriele, Anzellotti, Gian Marco, Armuzzi, Alessandro, Baldi, Fabiana, Barattucci, Ilaria, Barillaro, Christian, Barone, Fabiana, Bellantone, Rocco Domenico Alfonso, Bellieni, Andrea, Bello, Giuseppe, Benicchi, Andrea, Benvenuto, Francesca, Berardini, Ludovica, Berloco, Filippo, Bernabei, Roberto, Bianchi, Antonio, Biasucci, Daniele Guerino, Biasucci, Luigi Marzio, Bibbò, Stefano, Bini, Alessandra, Bisanti, Alessandra, Biscetti, Federico, Bocci, Maria Grazia, Bonadia, Nicola, Bongiovanni, Filippo, Borghetti, Alberto, Bosco, Giulia, Bosello, Silvia, Bove, Vincenzo, Bramato, Giulia, Brandi, Vincenzo, Bruni, Teresa, Bruno, Carmine, Bruno, Dario, Bungaro, Maria Chiara, Buonomo, Alessandro, Burzo, Livia, Calabrese, Angelo, Calvello, Maria Rosaria, Cambieri, Andrea, Cambise, Chiara, Cammà, Giulia, Candelli, Marcello, Canistro, Gennaro, Cantanale, Antonello, Capalbo, Gennaro, Capaldi, Lorenzo, Capone, Emanuele, Capristo, Esmeralda, Carbone, Luigi, Cardone, Silvia, Carelli, Simone, Carfì, Angelo, Carnicelli, Annamaria, Caruso, Cristiano, Casciaro, Francesco Antonio, Catalano, Lucio, Cauda, Roberto, Cecchini, Andrea Leonardo, Cerrito, Lucia, Cesarano, Melania, Chiarito, Annalisa, Cianci, Rossella, Cicchinelli, Sara, Ciccullo, Arturo, Cicetti, Marta, Ciciarello, Francesca, Cingolani, Antonella, Cipriani, Maria Camilla, Consalvo, Maria Ludovica, Coppola, Gaetano, Corbo, Giuseppe Maria, Corsello, Andrea, Costante, Federico, Costanzi, Matteo, Covino, Marcello, Crupi, Davide, Cutuli, Salvatore Lucio, D'Addio, Stefano, D'Alessandro, Alessia, D'AlfonsoD'Angelo, Maria ElenaEmanuela, D'Aversa, Francesca, Damiano, Fernando, De Berardinis, Gian Maria, De Cunzo, Tommaso, De Gaetano, Donati Katleen, De Luca, Giulio, De Matteis, Giuseppe, De Pascale, Gennaro, De Santis, Paolo, De Siena, Martina, De Vito, Francesco, Del Gatto, Valeria, Del Giacomo, Paola, Del Zompo, Fabio, Dell'Anna, Antonio Maria, Polla, Davide Della, Di Gialleonardo, Luca, Di Giambenedetto, Simona, Di Luca, Roberta, Di Maurizio, Luca, Di Muro, Mariangela, Dusina, Alex, Eleuteri, Davide, Esperide, Alessandra, Fachechi, Daniele, Faliero, Domenico, Falsiroli, Cinzia, Fantoni, Massimo, Fedele, Annalaura, Feliciani, Daniela, Ferrante, Cristina, Ferrone, Giuliano, Festa, Rossano, Fiore, Maria Chiara, Flex, Andrea, Forte, Evelina, Franceschi, Francesco, Francesconi, Alessandra, Franza, Laura, Funaro, Barbara, Fuorlo, Mariella, Fusco, Domenico, Gabrielli, Maurizio, Gaetani, Eleonora, Galletta, Claudia, Gallo, Antonella, Gambassi, Giovanni, Garcovich, Matteo, Gasbarrini, Antonio, Gasparrini, Irene, Gelli, Silvia, Giampietro, Antonella, Gigante, Laura, Giuliano, Gabriele, Giuliano, Giorgia, Giupponi, Bianca, Gremese, Elisa, Grieco, Domenico Luca, Guerrera, Manuel, Guglielmi, Valeria, Guidone, Caterina, Gullì, Antonio, Iaconelli, Amerigo, Iafrati, Aurora, Ianiro, Gianluca, Iaquinta, Angela, Impagnatiello, Michele, Inchingolo, Riccardo, Intini, Enrica, Iorio, Raffaele, Izzi, Immacolata Maria, Jovanovic, Tamara, Kadhim, Cristina, La Macchia, Rosa, La Milia, Daniele Ignazio, Landi, Francesco, Landi, Giovanni, Landi, Rosario, Landolfi, Raffaele, Leo, Massimo, Leone, Paolo Maria, Levantesi, Laura, Liguori, Antonio, Liperoti, Rosa, Lizzio, Marco Maria, Monaco, Maria Rita Lo, Locantore, Pietro, Lombardi, Francesco, Lombardi, Gianmarco, Lopetuso, Loris, Loria, Valentina, Losito, Angela Raffaella, Lucia, Mothanje Barbara Patricia, Macagno, Francesco, Macerola, Noemi, Maggi, Giampaolo, Maiuro, Giuseppe, Mancarella, Francesco, Mangiola, Francesca, Manno, Alberto, Marchesini, Debora, Maresca, Gian Marco, Marrone, Giuseppe, Martis, Ilaria, Martone, Anna Maria, Marzetti, Emanuele, Mattana, Chiara, Matteo, Maria Valeria, Maviglia, Riccardo, Mazzarella, Ada, Memoli, Carmen, Miele, Luca, Migneco, Alessio, Mignini, Irene, Milani, Alessandro, Milardi, Domenico, Montalto, Massimo, Montemurro, Giuliano, Monti, Flavia, Montini, Luca, Morena, Tony Christian, Morra, Vincenzina, Morretta, Chiara, Moschese, Davide, Murace, Celeste Ambra, Murdolo, Martina, Murri, Rita, Napoli, Marco, Nardella, Elisabetta, Natalello, Gerlando, Natalini, Daniele, Navarra, Simone Maria, Nesci, Antonio, Nicoletti, Alberto, Nicoletti, Rocco, Nicoletti, Tommaso Filippo, Nicolò, Rebecca, Nicolotti, Nicola, Nista, Enrico Celestino, Nuzzo, Eugenia, Oggiano, Marco, Ojetti, Veronica, Pagano, Francesco Cosimo, Paiano, Gianfranco, Pais, Cristina, Pallavicini, Federico, Palombo, Andrea, Paolillo, Federico, Papa, Alfredo, Papanice, Domenico, Papparella, Luigi Giovanni, Paratore, Mattia, Parrinello, Giuseppe, Pasciuto, Giuliana, Pasculli, Pierpaolo, Pecorini, Giovanni, Perniola, Simone, Pero, Erika, Petricca, Luca, Petrucci, Martina, Picarelli, Chiara, Piccioni, Andrea, Piccolo, Annalisa, Piervincenzi, Edoardo, Pignataro, Giulia, Pignataro, Raffaele, Pintaudi, Gabriele, Pisapia, Luca, Pizzoferrato, Marco, Pizzolante, Fabrizio, Pola, Roberto, Policola, Caterina, Pompili, Maurizio, Pontecorvi, Flavia, Pontecorvi, Valerio, Ponziani, Francesca, Popolla, Valentina, Porceddu, Enrica, Porfidia, Angelo, Porro, Lucia Maria, Potenza, Annalisa, Pozzana, Francesca, Privitera, Giuseppe, Pugliese, Daniela, Pulcini, Gabriele, Racco, Simona, Raffaelli, Francesca, Ramunno, Vittoria, Rapaccini, Gian Ludovico, Richeldi, Luca, Rinninella, Emanuele, Rocchi, Sara, Romanò, Bruno, Romano, Stefano, Rosa, Federico, Rossi, Laura, Rossi, Raimondo, Rossini, Enrica, Rota, Elisabetta, Rovedi, Fabiana, Rubino, Carlotta, Rumi, Gabriele, Russo, Andrea, Sabia, Luca, Salerno, Andrea, Salini, Sara, Salvatore, Lucia, Samori, Dehara, Sandroni, Claudio, Sanguinetti, Maurizio, Santarelli, Luca, Santini, Paolo, Santolamazza, Danilo, Santoliquido, Angelo, Santopaolo, Francesco, Santoro, Michele Cosimo, Sardeo, Francesco, Sarnari, Caterina, Saviano, Angela, Saviano, Luisa, Scaldaferri, Franco, Scarascia, Roberta, Schepis, Tommaso, Schiavello, Francesca, Scoppettuolo, Giancarlo, Sedda, Davide, Sessa, Flaminio, Sestito, Luisa, Settanni, Carlo, Siciliano, Matteo, Siciliano, Valentina, Sicuranza, Rossella, Simeoni, Benedetta, Simonetti, Jacopo, Smargiassi, Andrea, Soave, Paolo Maurizio, Sonnino, Chiara, Staiti, Domenico, Stella, Claudia, Stella, Leonardo, Stival, Eleonora, Taddei, Eleonora, Talerico, Rossella, Tamburello, Elio, Tamburrini, Enrica, Tanzarella, Eloisa Sofia, Tarascio, Elena, Tarli, Claudia, Tersali, Alessandra, Tilli, Pietro, Timpano, Jacopo, Torelli, Enrico, Torrini, Flavia, Tosato, Matteo, Tosoni, Alberto, Tricoli, Luca, Tritto, Marcello, Tumbarello, Mario, Tummolo, Anita Maria, Vallecoccia, Maria Sole, Valletta, Federico, Varone, Francesco, Vassalli, Francesco, Ventura, Giulio, Verardi, Lucrezia, Vetrone, Lorenzo, Vetrugno, Giuseppe, Visconti, Elena, Visconti, Felicia, Viviani, Andrea, Zaccaria, Raffaella, Zaccone, Carmelina, Zelano, Lorenzo, Dal Verme, Lorenzo Zileri, Zuccalà, Giuseppe, and Troiani, Eliana
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- 2020
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30. Different Impact of Definitions of Sarcopenia in Defining Frailty Status in a Population of Older Women with Early Breast Cancer
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Bellieni, Andrea, primary, Fusco, Domenico, additional, Sanchez, Alejandro Martin, additional, Franceschini, Gianluca, additional, Di Capua, Beatrice, additional, Allocca, Elena, additional, Di Stasio, Enrico, additional, Marazzi, Fabio, additional, Tagliaferri, Luca, additional, Masetti, Riccardo, additional, Bernabei, Roberto, additional, and Colloca, Giuseppe Ferdinando, additional
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- 2021
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31. Perspectives and limits of cancer treatment in an oldest old population
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Di Capua, Beatrice, primary, Bellieni, Andrea, additional, Fusco, Domenico, additional, Gambacorta, Maria Antonietta, additional, Tagliaferri, Luca, additional, Villani, Emanuele Rocco, additional, Bernabei, Roberto, additional, Valentini, Vincenzo, additional, and Colloca, Giuseppe Ferdinando, additional
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- 2021
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32. Subacute onset dystonia in a woman affected by Parkinson’s disease following SARS-COV-2 infection
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Lo Monaco, Maria Rita, primary, Bentivoglio, Anna Rita, additional, Fusco, Domenico, additional, Calabresi, Paolo, additional, and Piano, Carla, additional
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- 2021
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33. Assessment of neurological manifestations in hospitalized patients with COVID-19
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Luigetti, M., Iorio, R., Bentivoglio, A. R., Tricoli, L., Riso, V., Marotta, J., Piano, C., Primiano, G., Zileri Del Verme, L., Lo Monaco, M. R., Calabresi, P., Abbate, Valeria, Acampora, Nicola, Addolorato, Giovanni, Agostini, Fabiana, Ainora, Maria Elena, Akacha, Karim, Amato, Elena, Andreani, Francesca, Andriollo, Gloria, Annetta, Maria Giuseppina, Annicchiarico, Brigida Eleonora, Antonelli, Mariangela, Antonucci, Gabriele, Anzellotti, Gian Marco, Armuzzi, Alessandro, Baldi, Fabiana, Barattucci, Ilaria, Barillaro, Christian, Barone, Fabiana, Bellantone, Rocco Domenico Alfonso, Bellieni, Andrea, Bello, Giuseppe, Benicchi, Andrea, Benvenuto, Francesca, Berardini, Ludovica, Berloco, Filippo, Bernabei, Roberto, Bianchi, Antonio, Biasucci, Daniele Guerino, Biasucci, Luigi Marzio, Bibbò, Stefano, Bini, Alessandra, Bisanti, Alessandra, Biscetti, Federico, Bocci, Maria Grazia, Bonadia, Nicola, Bongiovanni, Filippo, Borghetti, Alberto, Bosco, Giulia, Bosello, Silvia, Bove, Vincenzo, Bramato, Giulia, Brandi, Vincenzo, Bruni, Teresa, Bruno, Carmine, Bruno, Dario, Bungaro, Maria Chiara, Buonomo, Alessandro, Burzo, Livia, Calabrese, Angelo, Calvello, Maria Rosaria, Cambieri, Andrea, Cambise, Chiara, Cammà, Giulia, Candelli, Marcello, Canistro, Gennaro, Cantanale, Antonello, Capalbo, Gennaro, Capaldi, Lorenzo, Capone, Emanuele, Capristo, Esmeralda, Carbone, Luigi, Cardone, Silvia, Carelli, Simone, Carfì, Angelo, Carnicelli, Annamaria, Caruso, Cristiano, Casciaro, Francesco Antonio, Catalano, Lucio, Cauda, Roberto, Cecchini, Andrea Leonardo, Cerrito, Lucia, Cesarano, Melania, Chiarito, Annalisa, Cianci, Rossella, Cicchinelli, Sara, Ciccullo, Arturo, Cicetti, Marta, Ciciarello, Francesca, Cingolani, Antonella, Cipriani, Maria Camilla, Consalvo, Maria Ludovica, Coppola, Gaetano, Corbo, Giuseppe Maria, Corsello, Andrea, Costante, Federico, Costanzi, Matteo, Covino, Marcello, Crupi, Davide, Cutuli, Salvatore Lucio, DAddio, Stefano, DAlessandro, Alessia, DAlfonso, Maria Elena, DAngelo, Emanuela, DAversa, Francesca, Damiano, Fernando, De Berardinis, Gian Maria, De Cunzo, Tommaso, De Gaetano, Donati Katleen, De Luca, Giulio, De Matteis, Giuseppe, De Pascale, Gennaro, De Santis, Paolo, De Siena, Martina, De Vito, Francesco, Del Gatto, Valeria, Del Giacomo, Paola, Del Zompo, Fabio, DellAnna, Antonio Maria, Della, Polla Davide, Di Gialleonardo, Luca, Di Giambenedetto, Simona, Di Luca, Roberta, Di Maurizio, Luca, Di Muro, Mariangela, Dusina, Alex, Eleuteri, Davide, Esperide, Alessandra, Fachechi, Daniele, Faliero, Domenico, Falsiroli, Cinzia, Fantoni, Massimo, Fedele, Annalaura, Feliciani, Daniela, Ferrante, Cristina, Ferrone, Giuliano, Festa, Rossano, Fiore, Maria Chiara, Flex, Andrea, Forte, Evelina, Franceschi, Francesco, Francesconi, Alessandra, Franza, Laura, Funaro, Barbara, Fuorlo, Mariella, Fusco, Domenico, Gabrielli, Maurizio, Gaetani, Eleonora, Galletta, Claudia, Gallo, Antonella, Gambassi, Giovanni, Garcovich, Matteo, Gasbarrini, Antonio, Gasparrini, Irene, Gelli, Silvia, Giampietro, Antonella, Gigante, Laura, Giuliano, Gabriele, Giuliano, Giorgia, Giupponi, Bianca, Gremese, Elisa, Grieco, Domenico Luca, Guerrera, Manuel, Guglielmi, Valeria, Guidone, Caterina, Gullì, Antonio, Iaconelli, Amerigo, Iafrati, Aurora, Ianiro, Gianluca, Iaquinta, Angela, Impagnatiello, Michele, Inchingolo, Riccardo, Intini, Enrica, Iorio, Raffaele, Izzi, Immacolata Maria, Jovanovic, Tamara, Kadhim, Cristina, La Macchia, Rosa, La Milia, Daniele Ignazio, Landi, Francesco, Landi, Giovanni, Landi, Rosario, Landolfi, Raffaele, Leo, Massimo, Leone, Paolo Maria, Levantesi, Laura, Liguori, Antonio, Liperoti, Rosa, Lizzio, Marco Maria, Lo Monaco Maria, Rita, Locantore, Pietro, Lombardi, Francesco, Lombardi, Gianmarco, Lopetuso, Loris, Loria, Valentina, Losito, Angela Raffaella, Lucia, Mothanje Barbara Patricia, Macagno, Francesco, Macerola, Noemi, Maggi, Giampaolo, Maiuro, Giuseppe, Mancarella, Francesco, Mangiola, Francesca, Manno, Alberto, Marchesini, Debora, Maresca, Gian Marco, Marrone, Giuseppe, Martis, Ilaria, Martone, Anna Maria, Marzetti, Emanuele, Mattana, Chiara, Matteo, Maria Valeria, Maviglia, Riccardo, Mazzarella, Ada, Memoli, Carmen, Miele, Luca, Migneco, Alessio, Mignini, Irene, Milani, Alessandro, Milardi, Domenico, Montalto, Massimo, Montemurro, Giuliano, Monti, Flavia, Montini, Luca, Morena, Tony Christian, Morra, Vincenzina, Morretta, Chiara, Moschese, Davide, Murace, Celeste Ambra, Murdolo, Martina, Murri, Rita, Napoli, Marco, Nardella, Elisabetta, Natalello, Gerlando, Natalini, Daniele, Navarra, Simone Maria, Nesci, Antonio, Nicoletti, Alberto, Nicoletti, Rocco, Nicoletti, Tommaso Filippo, Nicolò, Rebecca, Nicolotti, Nicola, Nista, Enrico Celestino, Nuzzo, Eugenia, Oggiano, Marco, Ojetti, Veronica, Pagano, Francesco Cosimo, Paiano, Gianfranco, Pais, Cristina, Pallavicini, Federico, Palombo, Andrea, Paolillo, Federico, Papa, Alfredo, Papanice, Domenico, Papparella, Luigi Giovanni, Paratore, Mattia, Parrinello, Giuseppe, Pasciuto, Giuliana, Pasculli, Pierpaolo, Pecorini, Giovanni, Perniola, Simone, Pero, Erika, Petricca, Luca, Petrucci, Martina, Picarelli, Chiara, Piccioni, Andrea, Piccolo, Annalisa, Piervincenzi, Edoardo, Pignataro, Giulia, Pignataro, Raffaele, Pintaudi, Gabriele, Pisapia, Luca, Pizzoferrato, Marco, Pizzolante, Fabrizio, Pola, Roberto, Policola, Caterina, Pompili, Maurizio, Pontecorvi, Flavia, Pontecorvi, Valerio, Ponziani, Francesca, Popolla, Valentina, Porceddu, Enrica, Porfidia, Angelo, Porro, Lucia Maria, Potenza, Annalisa, Pozzana, Francesca, Privitera, Giuseppe, Pugliese, Daniela, Pulcini, Gabriele, Racco, Simona, Raffaelli, Francesca, Ramunno, Vittoria, Rapaccini, Gian Ludovico, Richeldi, Luca, Rinninella, Emanuele, Rocchi, Sara, Romanò, Bruno, Romano, Stefano, Rosa, Federico, Rossi, Laura, Rossi, Raimondo, Rossini, Enrica, Rota, Elisabetta, Rovedi, Fabiana, Rubino, Carlotta, Rumi, Gabriele, Russo, Andrea, Sabia, Luca, Salerno, Andrea, Salini, Sara, Salvatore, Lucia, Samori, Dehara, Sandroni, Claudio, Sanguinetti, Maurizio, Santarelli, Luca, Santini, Paolo, Santolamazza, Danilo, Santoliquido, Angelo, Santopaolo, Francesco, Santoro, Michele Cosimo, Sardeo, Francesco, Sarnari, Caterina, Saviano, Angela, Saviano, Luisa, Scaldaferri, Franco, Scarascia, Roberta, Schepis, Tommaso, Schiavello, Francesca, Scoppettuolo, Giancarlo, Sedda, Davide, Sessa, Flaminio, Sestito, Luisa, Settanni, Carlo, Siciliano, Matteo, Siciliano, Valentina, Sicuranza, Rossella, Simeoni, Benedetta, Simonetti, Jacopo, Smargiassi, Andrea, Soave, Paolo Maurizio, Sonnino, Chiara, Staiti, Domenico, Stella, Claudia, Stella, Leonardo, Stival, Eleonora, Taddei, Eleonora, Talerico, Rossella, Tamburello, Elio, Tamburrini, Enrica, Tanzarella, Eloisa Sofia, Tarascio, Elena, Tarli, Claudia, Tersali, Alessandra, Tilli, Pietro, Timpano, Jacopo, Torelli, Enrico, Torrini, Flavia, Tosato, Matteo, Tosoni, Alberto, Tricoli, Luca, Tritto, Marcello, Tumbarello, Mario, Tummolo, Anita Maria, Vallecoccia, Maria Sole, Valletta, Federico, Varone, Francesco, Vassalli, Francesco, Ventura, Giulio, Verardi, Lucrezia, Vetrone, Lorenzo, Vetrugno, Giuseppe, Visconti, Elena, Visconti, Felicia, Viviani, Andrea, Zaccaria, Raffaella, Zaccone, Carmelina, Zelano, Lorenzo, Zileri Dal Verme, Lorenzo, and Zuccalà, Giuseppe
- Subjects
Male ,Hospitalized patients ,muscle ,Settore M-PSI/02 - PSICOBIOLOGIA E PSICOLOGIA FISIOLOGICA ,neurological disorders ,0302 clinical medicine ,Hyposmia ,030212 general & internal medicine ,Respiratory system ,education.field_of_study ,Brain Diseases ,Headache ,virus diseases ,Neuromuscular Diseases ,Middle Aged ,Hospitalization ,medicine.anatomical_structure ,Neurology ,Female ,medicine.symptom ,Adult ,medicine.medical_specialty ,SARS‐CoV2 ,Coronavirus disease 2019 (COVID-19) ,Patients ,Short Communication ,Anosmia ,precision medicine ,Population ,Encephalopathy ,Short Communications ,Clinical Neurology ,Settore MED/26 ,03 medical and health sciences ,COVID‐19 ,Internal medicine ,Throat ,Influenza, Human ,medicine ,Humans ,education ,Aged ,Retrospective Studies ,business.industry ,SARS-CoV-2 ,COVID-19 ,Hypoxia (medical) ,medicine.disease ,respiratory tract diseases ,body regions ,Neurology (clinical) ,Nervous System Diseases ,business ,030217 neurology & neurosurgery - Abstract
Background and purpose The objective of this study was to assess the neurological manifestations in a series of consecutive severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-positive patients, comparing their frequency with a population hospitalized in the same period for flu/respiratory symptoms, finally not related to SARS-CoV-2. Methods Patients with flu/respiratory symptoms admitted to Fondazione Policlinico Gemelli hospital from 14 March 2020 to 20 April 2020 were retrospectively enrolled. The frequency of neurological manifestations of patients with SARS-CoV-2 infection was compared with a control group. Results In all, 213 patients were found to be positive for SARS-CoV-2, after reverse transcriptase polymerase chain reaction on nasal or throat swabs, whilst 218 patients were found to be negative and were used as a control group. Regarding central nervous system manifestations, in SARS-CoV-2-positive patients a higher frequency of headache, hyposmia and encephalopathy always related to systemic conditions (fever or hypoxia) was observed. Furthermore, muscular involvement was more frequent in SARS-CoV-2 infection. Conclusions Patients with COVID-19 commonly have neurological manifestations but only hyposmia and muscle involvement seem more frequent compared with other flu diseases.
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- 2020
34. The “development of metabolic and functional markers of dementia in older people” (ODINO) study: Rationale, design and methods
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Picca, A., Ronconi, D., Coelho-Junior, H. J., Calvani, Riccardo, Marini, F., Biancolillo, A., Gervasoni, Jacopo, Primiano, A., Pais, C., Meloni, E., Fusco, Domenico, Lo Monaco, Maria Rita, Bernabei, Roberto, Camilla Cipriani, M., Marzetti, Emanuele, Liperoti, Rosa, Calvani R. (ORCID:0000-0001-5472-2365), Gervasoni J., Fusco D., Lo Monaco M. R. (ORCID:0000-0002-1457-7981), Bernabei R. (ORCID:0000-0002-9197-004X), Marzetti E. (ORCID:0000-0001-9567-6983), Liperoti R. (ORCID:0000-0003-3740-1687), Picca, A., Ronconi, D., Coelho-Junior, H. J., Calvani, Riccardo, Marini, F., Biancolillo, A., Gervasoni, Jacopo, Primiano, A., Pais, C., Meloni, E., Fusco, Domenico, Lo Monaco, Maria Rita, Bernabei, Roberto, Camilla Cipriani, M., Marzetti, Emanuele, Liperoti, Rosa, Calvani R. (ORCID:0000-0001-5472-2365), Gervasoni J., Fusco D., Lo Monaco M. R. (ORCID:0000-0002-1457-7981), Bernabei R. (ORCID:0000-0002-9197-004X), Marzetti E. (ORCID:0000-0001-9567-6983), and Liperoti R. (ORCID:0000-0003-3740-1687)
- Abstract
Mild cognitive impairment (MCI), also termed mild neurocognitive disorder, includes a heterogeneous group of conditions characterized by declines in one or more cognitive domains greater than that expected during "normal" aging but not severe enough to impair functional abilities. MCI has been associated with an increased risk of developing dementia and even considered an early stage of it. Therefore, noninvasively accessible biomarkers of MCI are highly sought after for early identification of the condition. Systemic inflammation, metabolic perturbations, and declining physical performance have been described in people with MCI. However, whether biological and functional parameters differ across MCI neuropsychological subtypes is presently debated. Likewise, the predictive value of existing biomarkers toward MCI conversion into dementia is unclear. The "develOpment of metabolic and functional markers of Dementia IN Older people" (ODINO) study was conceived as a multi-dimensional investigation in which multi-marker discovery will be coupled with innovative statistical approaches to characterize patterns of systemic inflammation, metabolic perturbations, and physical performance in older adults with MCI. The ultimate aim of ODINO is to identify potential biomarkers specific for MCI subtypes and predictive of MCI conversion into Alzheimer's disease or other forms of dementia over a three-year follow-up. Here, we describe the rationale, design, and methods of ODINO.
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- 2020
35. The New Challenge of Geriatrics: Saving Frail Older People from the SARS-COV-2 Pandemic Infection
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Landi, Francesco, Barillaro, Christian, Bellieni, Agnese, Brandi, Vincenzo, Carfì, A, D'Angelo, M, Fusco, Domenico, Landi, G, Lo Monaco, Maria Rita, Martone, Anna Maria, Marzetti, Emanuele, Pagano, Francesco Cosimo, Pais, C, Russo, A, Salini, S, Tosato, Matteo, Tummolo, Aida Angela, Benvenuto, F, Bramato, Giulia, Catalano, Lucio, Ciciarello, Francesca, Martis, I, Rocchi, Sara, Rota, E, Salerno, Andrea Maria, Tritto, M, Sgadari, Antonio, Zuccala', Giuseppe, Bernabei, Roberto, Landi, F (ORCID:0000-0002-3472-1389), Barillaro, C, Bellieni, A, Brandi, V, Fusco, D, Lo Monaco, R (ORCID:0000-0002-1457-7981), Martone, A M, Marzetti, E (ORCID:0000-0001-9567-6983), Pagano, F, Tosato, M, Tummolo, A, Bramato, G, Catalano, L, Ciciarello, F, Rocchi, S, Salerno, A, Sgadari, A (ORCID:0000-0002-8296-043X), Zuccalà, G (ORCID:0000-0002-2567-2220), Bernabei, R (ORCID:0000-0002-9197-004X), Landi, Francesco, Barillaro, Christian, Bellieni, Agnese, Brandi, Vincenzo, Carfì, A, D'Angelo, M, Fusco, Domenico, Landi, G, Lo Monaco, Maria Rita, Martone, Anna Maria, Marzetti, Emanuele, Pagano, Francesco Cosimo, Pais, C, Russo, A, Salini, S, Tosato, Matteo, Tummolo, Aida Angela, Benvenuto, F, Bramato, Giulia, Catalano, Lucio, Ciciarello, Francesca, Martis, I, Rocchi, Sara, Rota, E, Salerno, Andrea Maria, Tritto, M, Sgadari, Antonio, Zuccala', Giuseppe, Bernabei, Roberto, Landi, F (ORCID:0000-0002-3472-1389), Barillaro, C, Bellieni, A, Brandi, V, Fusco, D, Lo Monaco, R (ORCID:0000-0002-1457-7981), Martone, A M, Marzetti, E (ORCID:0000-0001-9567-6983), Pagano, F, Tosato, M, Tummolo, A, Bramato, G, Catalano, L, Ciciarello, F, Rocchi, S, Salerno, A, Sgadari, A (ORCID:0000-0002-8296-043X), Zuccalà, G (ORCID:0000-0002-2567-2220), and Bernabei, R (ORCID:0000-0002-9197-004X)
- Abstract
No abstract available
- Published
- 2020
36. Tolerability of bevacizumab in elderly ovarian cancer patients (Turbo study): A case-control study of a real-life experience
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Amadio, G., Marchetti, Claudia, Villani, Emanuele Rocco, Fusco, Domenico, Stollagli, F., Bottoni, C., Distefano, Maria Grazia, Colloca, Giuseppe Ferdinando, Scambia, Giovanni, Fagotti, Anna, Marchetti C. (ORCID:0000-0001-7098-8956), Villani E. R., Fusco D., Distefano M., Colloca G., Scambia G. (ORCID:0000-0003-2758-1063), Fagotti A. (ORCID:0000-0001-5579-335X), Amadio, G., Marchetti, Claudia, Villani, Emanuele Rocco, Fusco, Domenico, Stollagli, F., Bottoni, C., Distefano, Maria Grazia, Colloca, Giuseppe Ferdinando, Scambia, Giovanni, Fagotti, Anna, Marchetti C. (ORCID:0000-0001-7098-8956), Villani E. R., Fusco D., Distefano M., Colloca G., Scambia G. (ORCID:0000-0003-2758-1063), and Fagotti A. (ORCID:0000-0001-5579-335X)
- Abstract
Objective: Bevacizumab maintenance following platinum-based chemotherapy is an effective treatment for epithelial ovarian cancer (EOC), both in primary and recurrent disease. Our aim was to identify criteria to select elderly patients who can safely benefit from bevacizumab addition. Methods: This is a case-control study on patients with primary or recurrent EOC who received platinum-based chemotherapy plus bevacizumab, between January 2015 and December 2016. Patient characteristics, treatment details and adverse events were reviewed and analyzed in 2 settings: younger (<65 years, group 1) and elderly (≥65 years, group 2). A binary logistic model was applied to correlate clinical variables and severe (grade ≥3) toxicity risk. Results: Overall, 283 patients with EOC were included, with 72 (25.4%) older patients compared with 211 (74.6%) younger women. Bevacizumab had been administered to 234 patients (82.7%) as first-line treatment and in 49 (17.3%) with recurrent disease. At diagnosis, elderly patients presented with at least one comorbidity and were taking at least 1 medication in 84.7% and 80.6% of the cases respectively, compared with correspondingly 47.4% and 37.4% in group 1 (p<0.001). Nonetheless, the occurrence of serious (grade ≥3) adverse events did not increase among the older group. Creatinine serum levels >1.1 g/dL, estimated glomerular filtration rate (eGFR) ≤60 mL/min, ≥3 comorbidities were independently associated with a higher severe toxicity. Conclusions: Elderly patients with EOC can safely be treated with bevacizumab; factors other than age, as higher creatinine serum levels, eGFR and number of comorbidities should be considered to better estimate bevacizumab-related toxicity risk.
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- 2020
37. COVID-19 and intestinal inflammation: Role of fecal calprotectin
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Ojetti, Veronica, primary, Saviano, Angela, additional, Covino, Marcello, additional, Acampora, Nicola, additional, Troiani, Eliana, additional, Franceschi, Francesco, additional, Abbate, Valeria, additional, Addolorato, Giovanni, additional, Agostini, Fabiana, additional, Ainora, Maria Elena, additional, Akacha, Karim, additional, Amato, Elena, additional, Andreani, Francesca, additional, Andriollo, Gloria, additional, Annetta, Maria Giuseppina, additional, Annicchiarico, Brigida Eleonora, additional, Antonelli, Mariangela, additional, Antonucci, Gabriele, additional, Anzellotti, Gian Marco, additional, Armuzzi, Alessandro, additional, Baldi, Fabiana, additional, Barattucci, Ilaria, additional, Barillaro, Christian, additional, Barone, Fabiana, additional, Bellantone, Rocco Domenico Alfonso, additional, Bellieni, Andrea, additional, Bello, Giuseppe, additional, Benicchi, Andrea, additional, Benvenuto, Francesca, additional, Berardini, Ludovica, additional, Berloco, Filippo, additional, Bernabei, Roberto, additional, Bianchi, Antonio, additional, Biasucci, Daniele Guerino, additional, Biasucci, Luigi Marzio, additional, Bibbò, Stefano, additional, Bini, Alessandra, additional, Bisanti, Alessandra, additional, Biscetti, Federico, additional, Bocci, Maria Grazia, additional, Bonadia, Nicola, additional, Bongiovanni, Filippo, additional, Borghetti, Alberto, additional, Bosco, Giulia, additional, Bosello, Silvia, additional, Bove, Vincenzo, additional, Bramato, Giulia, additional, Brandi, Vincenzo, additional, Bruni, Teresa, additional, Bruno, Carmine, additional, Bruno, Dario, additional, Bungaro, Maria Chiara, additional, Buonomo, Alessandro, additional, Burzo, Livia, additional, Calabrese, Angelo, additional, Calvello, Maria Rosaria, additional, Cambieri, Andrea, additional, Cambise, Chiara, additional, Cammà, Giulia, additional, Candelli, Marcello, additional, Canistro, Gennaro, additional, Cantanale, Antonello, additional, Capalbo, Gennaro, additional, Capaldi, Lorenzo, additional, Capone, Emanuele, additional, Capristo, Esmeralda, additional, Carbone, Luigi, additional, Cardone, Silvia, additional, Carelli, Simone, additional, Carfì, Angelo, additional, Carnicelli, Annamaria, additional, Caruso, Cristiano, additional, Casciaro, Francesco Antonio, additional, Catalano, Lucio, additional, Cauda, Roberto, additional, Cecchini, Andrea Leonardo, additional, Cerrito, Lucia, additional, Cesarano, Melania, additional, Chiarito, Annalisa, additional, Cianci, Rossella, additional, Cicchinelli, Sara, additional, Ciccullo, Arturo, additional, Cicetti, Marta, additional, Ciciarello, Francesca, additional, Cingolani, Antonella, additional, Cipriani, Maria Camilla, additional, Consalvo, Maria Ludovica, additional, Coppola, Gaetano, additional, Corbo, Giuseppe Maria, additional, Corsello, Andrea, additional, Costante, Federico, additional, Costanzi, Matteo, additional, Crupi, Davide, additional, Cutuli, Salvatore Lucio, additional, D'Addio, Stefano, additional, D'Alessandro, Alessia, additional, D'AlfonsoD'Angelo, Maria ElenaEmanuela, additional, D'Aversa, Francesca, additional, Damiano, Fernando, additional, De Berardinis, Gian Maria, additional, De Cunzo, Tommaso, additional, De Gaetano, Donati Katleen, additional, De Luca, Giulio, additional, De Matteis, Giuseppe, additional, De Pascale, Gennaro, additional, De Santis, Paolo, additional, De Siena, Martina, additional, De Vito, Francesco, additional, Del Gatto, Valeria, additional, Del Giacomo, Paola, additional, Del Zompo, Fabio, additional, Dell'Anna, Antonio Maria, additional, Polla, Davide Della, additional, Di Gialleonardo, Luca, additional, Di Giambenedetto, Simona, additional, Di Luca, Roberta, additional, Di Maurizio, Luca, additional, Di Muro, Mariangela, additional, Dusina, Alex, additional, Eleuteri, Davide, additional, Esperide, Alessandra, additional, Fachechi, Daniele, additional, Faliero, Domenico, additional, Falsiroli, Cinzia, additional, Fantoni, Massimo, additional, Fedele, Annalaura, additional, Feliciani, Daniela, additional, Ferrante, Cristina, additional, Ferrone, Giuliano, additional, Festa, Rossano, additional, Fiore, Maria Chiara, additional, Flex, Andrea, additional, Forte, Evelina, additional, Francesconi, Alessandra, additional, Franza, Laura, additional, Funaro, Barbara, additional, Fuorlo, Mariella, additional, Fusco, Domenico, additional, Gabrielli, Maurizio, additional, Gaetani, Eleonora, additional, Galletta, Claudia, additional, Gallo, Antonella, additional, Gambassi, Giovanni, additional, Garcovich, Matteo, additional, Gasbarrini, Antonio, additional, Gasparrini, Irene, additional, Gelli, Silvia, additional, Giampietro, Antonella, additional, Gigante, Laura, additional, Giuliano, Gabriele, additional, Giuliano, Giorgia, additional, Giupponi, Bianca, additional, Gremese, Elisa, additional, Grieco, Domenico Luca, additional, Guerrera, Manuel, additional, Guglielmi, Valeria, additional, Guidone, Caterina, additional, Gullì, Antonio, additional, Iaconelli, Amerigo, additional, Iafrati, Aurora, additional, Ianiro, Gianluca, additional, Iaquinta, Angela, additional, Impagnatiello, Michele, additional, Inchingolo, Riccardo, additional, Intini, Enrica, additional, Iorio, Raffaele, additional, Izzi, Immacolata Maria, additional, Jovanovic, Tamara, additional, Kadhim, Cristina, additional, La Macchia, Rosa, additional, La Milia, Daniele Ignazio, additional, Landi, Francesco, additional, Landi, Giovanni, additional, Landi, Rosario, additional, Landolfi, Raffaele, additional, Leo, Massimo, additional, Leone, Paolo Maria, additional, Levantesi, Laura, additional, Liguori, Antonio, additional, Liperoti, Rosa, additional, Lizzio, Marco Maria, additional, Monaco, Maria Rita Lo, additional, Locantore, Pietro, additional, Lombardi, Francesco, additional, Lombardi, Gianmarco, additional, Lopetuso, Loris, additional, Loria, Valentina, additional, Losito, Angela Raffaella, additional, Lucia, Mothanje Barbara Patricia, additional, Macagno, Francesco, additional, Macerola, Noemi, additional, Maggi, Giampaolo, additional, Maiuro, Giuseppe, additional, Mancarella, Francesco, additional, Mangiola, Francesca, additional, Manno, Alberto, additional, Marchesini, Debora, additional, Maresca, Gian Marco, additional, Marrone, Giuseppe, additional, Martis, Ilaria, additional, Martone, Anna Maria, additional, Marzetti, Emanuele, additional, Mattana, Chiara, additional, Matteo, Maria Valeria, additional, Maviglia, Riccardo, additional, Mazzarella, Ada, additional, Memoli, Carmen, additional, Miele, Luca, additional, Migneco, Alessio, additional, Mignini, Irene, additional, Milani, Alessandro, additional, Milardi, Domenico, additional, Montalto, Massimo, additional, Montemurro, Giuliano, additional, Monti, Flavia, additional, Montini, Luca, additional, Morena, Tony Christian, additional, Morra, Vincenzina, additional, Morretta, Chiara, additional, Moschese, Davide, additional, Murace, Celeste Ambra, additional, Murdolo, Martina, additional, Murri, Rita, additional, Napoli, Marco, additional, Nardella, Elisabetta, additional, Natalello, Gerlando, additional, Natalini, Daniele, additional, Navarra, Simone Maria, additional, Nesci, Antonio, additional, Nicoletti, Alberto, additional, Nicoletti, Rocco, additional, Nicoletti, Tommaso Filippo, additional, Nicolò, Rebecca, additional, Nicolotti, Nicola, additional, Nista, Enrico Celestino, additional, Nuzzo, Eugenia, additional, Oggiano, Marco, additional, Ojetti, Veronica, additional, Pagano, Francesco Cosimo, additional, Paiano, Gianfranco, additional, Pais, Cristina, additional, Pallavicini, Federico, additional, Palombo, Andrea, additional, Paolillo, Federico, additional, Papa, Alfredo, additional, Papanice, Domenico, additional, Papparella, Luigi Giovanni, additional, Paratore, Mattia, additional, Parrinello, Giuseppe, additional, Pasciuto, Giuliana, additional, Pasculli, Pierpaolo, additional, Pecorini, Giovanni, additional, Perniola, Simone, additional, Pero, Erika, additional, Petricca, Luca, additional, Petrucci, Martina, additional, Picarelli, Chiara, additional, Piccioni, Andrea, additional, Piccolo, Annalisa, additional, Piervincenzi, Edoardo, additional, Pignataro, Giulia, additional, Pignataro, Raffaele, additional, Pintaudi, Gabriele, additional, Pisapia, Luca, additional, Pizzoferrato, Marco, additional, Pizzolante, Fabrizio, additional, Pola, Roberto, additional, Policola, Caterina, additional, Pompili, Maurizio, additional, Pontecorvi, Flavia, additional, Pontecorvi, Valerio, additional, Ponziani, Francesca, additional, Popolla, Valentina, additional, Porceddu, Enrica, additional, Porfidia, Angelo, additional, Porro, Lucia Maria, additional, Potenza, Annalisa, additional, Pozzana, Francesca, additional, Privitera, Giuseppe, additional, Pugliese, Daniela, additional, Pulcini, Gabriele, additional, Racco, Simona, additional, Raffaelli, Francesca, additional, Ramunno, Vittoria, additional, Rapaccini, Gian Ludovico, additional, Richeldi, Luca, additional, Rinninella, Emanuele, additional, Rocchi, Sara, additional, Romanò, Bruno, additional, Romano, Stefano, additional, Rosa, Federico, additional, Rossi, Laura, additional, Rossi, Raimondo, additional, Rossini, Enrica, additional, Rota, Elisabetta, additional, Rovedi, Fabiana, additional, Rubino, Carlotta, additional, Rumi, Gabriele, additional, Russo, Andrea, additional, Sabia, Luca, additional, Salerno, Andrea, additional, Salini, Sara, additional, Salvatore, Lucia, additional, Samori, Dehara, additional, Sandroni, Claudio, additional, Sanguinetti, Maurizio, additional, Santarelli, Luca, additional, Santini, Paolo, additional, Santolamazza, Danilo, additional, Santoliquido, Angelo, additional, Santopaolo, Francesco, additional, Santoro, Michele Cosimo, additional, Sardeo, Francesco, additional, Sarnari, Caterina, additional, Saviano, Luisa, additional, Scaldaferri, Franco, additional, Scarascia, Roberta, additional, Schepis, Tommaso, additional, Schiavello, Francesca, additional, Scoppettuolo, Giancarlo, additional, Sedda, Davide, additional, Sessa, Flaminio, additional, Sestito, Luisa, additional, Settanni, Carlo, additional, Siciliano, Matteo, additional, Siciliano, Valentina, additional, Sicuranza, Rossella, additional, Simeoni, Benedetta, additional, Simonetti, Jacopo, additional, Smargiassi, Andrea, additional, Soave, Paolo Maurizio, additional, Sonnino, Chiara, additional, Staiti, Domenico, additional, Stella, Claudia, additional, Stella, Leonardo, additional, Stival, Eleonora, additional, Taddei, Eleonora, additional, Talerico, Rossella, additional, Tamburello, Elio, additional, Tamburrini, Enrica, additional, Tanzarella, Eloisa Sofia, additional, Tarascio, Elena, additional, Tarli, Claudia, additional, Tersali, Alessandra, additional, Tilli, Pietro, additional, Timpano, Jacopo, additional, Torelli, Enrico, additional, Torrini, Flavia, additional, Tosato, Matteo, additional, Tosoni, Alberto, additional, Tricoli, Luca, additional, Tritto, Marcello, additional, Tumbarello, Mario, additional, Tummolo, Anita Maria, additional, Vallecoccia, Maria Sole, additional, Valletta, Federico, additional, Varone, Francesco, additional, Vassalli, Francesco, additional, Ventura, Giulio, additional, Verardi, Lucrezia, additional, Vetrone, Lorenzo, additional, Vetrugno, Giuseppe, additional, Visconti, Elena, additional, Visconti, Felicia, additional, Viviani, Andrea, additional, Zaccaria, Raffaella, additional, Zaccone, Carmelina, additional, Zelano, Lorenzo, additional, Dal Verme, Lorenzo Zileri, additional, and Zuccalà, Giuseppe, additional
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- 2020
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38. Association of Pisa Syndrome With Mortality in Patients With Parkinson's Disease
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Laudisio, Alice, Lo Monaco, Maria Rita, Vetrano, Davide L., Pisciotta, Maria Stella, Brandi, Vincenzo, Gemma, Antonella, Fusco, Domenico, Bernabei, Roberto, Antonelli Incalzi, Raffaele, and Zuccalà, Giuseppe
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- 2019
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39. The importance of geriatric and surgical co-management of elderly in muscoloskeletal oncology: A literature review
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Vitiello, Raffaele, primary, Bellieni, Andrea, additional, Oliva, Maria Serena, additional, Di Capua, Beatrice, additional, Fusco, Domenico, additional, Careri, Silvia, additional, Colloca, Giuseppe Ferdinando, additional, Perisano, Carlo, additional, Maccauro, Giulio, additional, and Lillo, Marco, additional
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- 2020
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40. What about the caregiver? A journey into Parkinson’s disease following the burden tracks
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Lo Monaco, Maria Rita, primary, Di Stasio, Enrico, additional, Ricciardi, Diego, additional, Solito, Marcella, additional, Petracca, Martina, additional, Fusco, Domenico, additional, Onder, Graziano, additional, Landi, Giovanni, additional, Zuccalà, Giuseppe, additional, Liperoti, Rosa, additional, Cipriani, Maria Camilla, additional, Brisi, Caterina, additional, Bernabei, Roberto, additional, Silveri, Maria Caterina, additional, and Bentivoglio, Anna Rita, additional
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- 2020
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41. The “develOpment of metabolic and functional markers of Dementia IN Older people” (ODINO) Study: Rationale, Design and Methods
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Picca, Anna, primary, Ronconi, Daniela, additional, Coelho-Junior, Hélio J., additional, Calvani, Riccardo, additional, Marini, Federico, additional, Biancolillo, Alessandra, additional, Gervasoni, Jacopo, additional, Primiano, Aniello, additional, Pais, Cristina, additional, Meloni, Eleonora, additional, Fusco, Domenico, additional, Lo Monaco, Maria Rita, additional, Bernabei, Roberto, additional, Cipriani, Maria Camilla, additional, Marzetti, Emanuele, additional, and Liperoti, Rosa, additional
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- 2020
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42. Comorbidity assessment to determine prognosis in older adult patients with classical Hodgkin lymphoma
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Galli, Eugenio, primary, Cuccaro, Annarosa, additional, Maiolo, Elena, additional, Bellesi, Silvia, additional, D'Alò, Francesco, additional, Fusco, Domenico, additional, Colloca, Giuseppe, additional, De Stefano, Valerio, additional, and Hohaus, Stefan, additional
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- 2020
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43. ToleRability of BevacizUmab in elderly Ovarian cancer patients (TURBO study): a case-control study of a real-life experience
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Amadio, Giulia, primary, Marchetti, Claudia, additional, Villani, Emanuele Rocco, additional, Fusco, Domenico, additional, Stollagli, Francesca, additional, Bottoni, Carolina, additional, Distefano, Mariagrazia, additional, Colloca, Giuseppe, additional, Scambia, Giovanni, additional, and Fagotti, Anna, additional
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- 2020
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44. Association of Pisa Syndrome With Mortality in Patients With Parkinson's Disease
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Laudisio, A, Lo Monaco, Maria Rita, Vetrano, Dl, Pisciotta, M, Brandi, V, Gemma, A, Fusco, Domenico, Bernabei, Roberto, Antonelli Incalzi, R, Zuccala', Giuseppe, Lo Monaco MR (ORCID:0000-0002-1457-7981), Fusco D, Bernabei R (ORCID:0000-0002-9197-004X), Zuccalà G (ORCID:0000-0002-2567-2220), Laudisio, A, Lo Monaco, Maria Rita, Vetrano, Dl, Pisciotta, M, Brandi, V, Gemma, A, Fusco, Domenico, Bernabei, Roberto, Antonelli Incalzi, R, Zuccala', Giuseppe, Lo Monaco MR (ORCID:0000-0002-1457-7981), Fusco D, Bernabei R (ORCID:0000-0002-9197-004X), and Zuccalà G (ORCID:0000-0002-2567-2220)
- Abstract
OBJECTIVES: In Parkinson's disease, Pisa syndrom (PS) has been associated with disease stage and severity, combined treatment with levodopa and dopamine agonists, gait disorders, and comorbidities. Some forms of PS are potentially reversible; nevertheless, little is known about the impact of this syndrome on survival. DESIGN: Prospective study with a median follow-up of 2 years. SETTING AND PARTICIPANTS: Patients with Parkinson's disease, age 65 years and older (N = 189), attending a geriatric day hospital. MEASUREMENTS: According to established criteria, PS was diagnosed in the presence of at least 10° lateral flexion of the trunk reducible by passive mobilization or supine positioning. Cox regression was adopted to assess the association of PS with all-cause mortality. RESULTS: PS was diagnosed in 40 patients (21%); over the follow-up, 21 (11%) subjects died. In Cox regression, PS was associated with higher mortality [hazard ratio (HR) 4.10; 95% confidence interval (CI) = 1.36-12.38], after adjusting; other variables associated with mortality were age (HR = 1.19, 95% CI = 1.08-1.32), beta blockers (HR = 4.35, 95% CI = 1.23-15.39), and albumin levels (HR = 0.05, 95% CI = 0.01-0.33). The association of PS with mortality remained significant also after adjusting for variables associated with this syndrome (HR = 4.04, 95% CI = 1.33-12.25). CONCLUSIONS/IMPLICATIONS: PS represents a risk factor for earlier mortality in Parkinson's disease; further studies are needed to ascertain the underlying causes and whether treatment of this condition might improve survival.
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- 2019
45. Untangling the relationship between fat distribution, nutritional status and Parkinson's disease severity
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Pisciotta, Maria S, Fusco, Domenico, Grande, Giulia, Brandi, Vincenzo, Lo Monaco, Maria Rita, Laudisio, Alice, Onder, Graziano, Bentivoglio, Anna Rita, Ricciardi, Diego, Bernabei, Roberto, Zuccala', Giuseppe, Vetrano, Davide L, Lo Monaco, Maria R (ORCID:0000-0002-1457-7981), Onder, Graziano (ORCID:0000-0003-3400-4491), Bentivoglio, Anna R (ORCID:0000-0002-9663-095X), Bernabei, Roberto (ORCID:0000-0002-9197-004X), Zuccalà, Giuseppe (ORCID:0000-0002-2567-2220), Pisciotta, Maria S, Fusco, Domenico, Grande, Giulia, Brandi, Vincenzo, Lo Monaco, Maria Rita, Laudisio, Alice, Onder, Graziano, Bentivoglio, Anna Rita, Ricciardi, Diego, Bernabei, Roberto, Zuccala', Giuseppe, Vetrano, Davide L, Lo Monaco, Maria R (ORCID:0000-0002-1457-7981), Onder, Graziano (ORCID:0000-0003-3400-4491), Bentivoglio, Anna R (ORCID:0000-0002-9663-095X), Bernabei, Roberto (ORCID:0000-0002-9197-004X), and Zuccalà, Giuseppe (ORCID:0000-0002-2567-2220)
- Abstract
BACKGROUND: Parkinson's disease (PD) is responsible for significant changes in body composition. AIMS: We aimed to test the association between PD severity and fat distribution patterns, and to investigate the potential modifier effect of nutritional status in this association. METHODS: We enrolled 195 PD subjects consecutively admitted to a university geriatric day hospital. All participants underwent comprehensive clinical evaluation, including assessment of total and regional body composition (dual-energy X-ray absorptiometry, DXA), body mass index, nutritional status (Mini-Nutritional Assessment, MNA), motor disease severity (UPDRS III), comorbidities, and pharmacotherapy. RESULTS: The fully adjusted linear regression model showed a negative association between UPDRS III and total body fat in kg and percentage (respectively, B - 0.79; 95% CI - 1.54 to - 0.05 and B - 0.55; 95% CI - 1.04 to - 0.05), percentage android fat (B - 1.07; 95% CI - 1.75 to - 0.39), trunk-leg fat ratio (B - 0.02; 95% CI - 0.04 to - 0.01), trunk-limb fat ratio (B - 0.01; 95% CI - 0.06 to - 0.01) and android-gynoid fat ratio (B - 0.01; 95% CI - 0.03 to - 0.01). After stratification by MNA score, all the parameters of android-like fat distribution resulted negatively associated (p < 0.001 for all) with UPDRS III, but only among subjects with a MNA < 23.5 (risk of malnutrition or malnutrition). CONCLUSION: We found a negative association between severity of motor impairment and total fat mass in PD, more specific with respect to an android pattern of fat distribution. This association seems to be driven by nutritional status, and is significant only among patients at risk of malnutrition or with overt malnutrition.
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- 2019
46. ToleRability of BevacizUmab in elderly Ovarian cancer patients (TURBO study): a case-control study of a real-life experience.
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Scambia, Giovanni, primary, amadio, giulia, primary, Marchetti, Claudia, primary, Rocco Villani, Emanuele, primary, Stollagli, Francesca, primary, Bottoni, Carolina, primary, distefano, mariagrazia, primary, Colloca, Giuseppe, primary, Fagotti, Anna, primary, and Fusco, Domenico, primary
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- 2019
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47. Untangling the relationship between fat distribution, nutritional status and Parkinson’s disease severity
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Pisciotta, Maria S., primary, Fusco, Domenico, additional, Grande, Giulia, additional, Brandi, Vincenzo, additional, Lo Monaco, Maria R., additional, Laudisio, Alice, additional, Onder, Graziano, additional, Bentivoglio, Anna R., additional, Ricciardi, Diego, additional, Bernabei, Roberto, additional, Zuccalà, Giuseppe, additional, and Vetrano, Davide L., additional
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- 2019
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48. Comprehensive geriatric assessment in older adults with cancer: Recommendations by the Italian Society of Geriatrics and Gerontology (SIGG).
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Fusco, Domenico, Ferrini, Alessandro, Pasqualetti, Giuseppe, Giannotti, Chiara, Cesari, Matteo, Laudisio, Alice, Ballestrero, Alberto, Scabini, Stefano, Odetti, Patrizio R., Colloca, Giuseppe F., Monzani, Fabio, Nencioni, Alessio, Antonelli Incalzi, Raffaele, and Monacelli, Fiammetta
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CANCER patients , *OLDER people , *GERIATRIC assessment , *GERONTOLOGY , *OLDER patients - Abstract
Introduction: Optimizing the approach to older adults with cancer is now a priority given the increasing frequency of new cancer diagnoses that are made in the older population. The comprehensive geriatric assessment (CGA) represents the gold‐standard for (1) defining prognosis and ability to withstand cancer treatments, (2) exploring the multiple aspects that define the complexity of frail older persons, and (3) designing person‐tailored interventions. Materials and methods: In this document, based on a comprehensive revision of the literature, the Italian Society for Geriatrics and Gerontology proposes a CGA model (ONCOGER CGA) to be adopted by oncology centers for their routine approach to older patients with cancer. Results and discussion: A widespread use of this standardized CGA format will facilitate comparisons across institutions, promote studies based on a multidimensional patient assessment, and foster the inclusion of geriatric endpoints in oncological clinical trials. Furthermore, we predict that the use of a standardized CGA approach will increase the integration of geriatricians into oncology care teams with the final result of improving therapeutic choices and clinical outcomes. [ABSTRACT FROM AUTHOR]
- Published
- 2021
- Full Text
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49. Laterality in Parkinson's disease may predict motor and visual imagery abilities
- Author
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Lo Monaco, Maria Rita, Laudisio, Alice, Fusco, Domenico, Vetrano, Davide Liborio, Ricciardi, Diego, Delle Donne, Valentina, Proietti, Francesca, Zuccala', Giuseppe, Silveri, Maria Caterina, Lo Monaco MR (ORCID:0000-0002-1457-7981), Laudisio A, Fusco D, Vetrano DL, Ricciardi D, Delle Donne V, Zuccalà G (ORCID:0000-0002-2567-2220), Silveri MC (ORCID:0000-0001-5012-0682), Lo Monaco, Maria Rita, Laudisio, Alice, Fusco, Domenico, Vetrano, Davide Liborio, Ricciardi, Diego, Delle Donne, Valentina, Proietti, Francesca, Zuccala', Giuseppe, Silveri, Maria Caterina, Lo Monaco MR (ORCID:0000-0002-1457-7981), Laudisio A, Fusco D, Vetrano DL, Ricciardi D, Delle Donne V, Zuccalà G (ORCID:0000-0002-2567-2220), and Silveri MC (ORCID:0000-0001-5012-0682)
- Abstract
Experimental evidence suggests that motor imagery (MI) engages the same neural substrates supporting actual motor activities and is likely impaired when such substrates are damaged, as in Parkinson's disease (PD). MI intuitively relies on visual imagery (VI), because mental simulations of physical movements depend on the visual retrieval of these movements. Although VI is generally considered a right hemispheric function, the hemispheric dominance of MI is still in dispute. Disparities in sidedness of motor disturbances are a distinctive feature of PD, and recent findings indicate that such disparities may similarly characterize cognition. Specifically, the deficits observed may depend upon which hemisphere is principally involved. Essentially, MI and VI are cognitive tasks subject to differential impairment and reflecting the prevalence of hemispheric impairment in PD. Motor imagery (assessed by the Vividness of Motor Imagery Questionnaire [VMIQ]) and VI (assessed by the Vividness of Visual Imagery Questionnaire [VVIQ] and Test of Visual Imagery Control [TVIC]) were examined in patients with asymmetric PD and in healthy elderly control subjects (HC group). VMIQ scores were similar in PD laterality subsets and the HC group, but VVIQ scores were significantly lower in both PD groups compared with the HC group. TVIC scores were significantly lower in the presence of left motor (right hemispheric) impairment and were predictive of left motor (right hemispheric) impairment. We suspect that MI is strongly reliant on VI and that language may mediate these two functions, to the extent that both are evoked through verbal stimuli. Working memory, both visual and verbal, is also involved in MI and VI tasks. Without due attention to laterality of symptoms, any training incorporating MI and VI may not deliver expected outcomes in the setting of asymmetric PD symptomatology.
- Published
- 2018
50. Prevalence of Impulsive-Compulsive Symptoms in Elderly Parkinson’s Disease Patients
- Author
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Monaco, Maria Rita Lo, primary, Petracca, Martina, additional, Weintraub, Daniel, additional, Fusco, Domenico, additional, Liperoti, Rosa, additional, Zuccalà, Giuseppe, additional, Carpia, Domenico La, additional, Vetrano, Davide Liborio, additional, Genovese, Danilo, additional, Pisciotta, Maria Stella, additional, Brandi, Vincenzo, additional, Padua, Luca, additional, Imbimbo, Isabella, additional, Ricciardi, Diego, additional, Bernabei, Roberto, additional, Silveri, Maria Caterina, additional, Laudisio, Alice, additional, and Bentivoglio, Anna Rita, additional
- Published
- 2018
- Full Text
- View/download PDF
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