Search

Your search keyword '"Fred J. Fleitz"' showing total 1 results
Start Over Author "Fred J. Fleitz" Publication Year Range Last 10 years

Refine your results

1 results on '"Fred J. Fleitz"'

1. Bio- and Chemocatalysis for the Synthesis of Late Stage SAR-Enabling Intermediates for ROMK Inhibitors and MK-7145 for the Treatment of Hypertension and Heart Failure

Author

Ian Mangion, Rebecca T. Ruck, Fred J. Fleitz, Lushi Tan, Jongrock Kong, Qinghao Chen, and Nelo R. Rivera

Subjects
010405 organic chemistry, Chemistry, Organic Chemistry, Late stage, Pharmacology, 010402 general chemistry, medicine.disease, 01 natural sciences, 0104 chemical sciences, Heart failure, ROMK, medicine, Physical and Theoretical Chemistry, human activities
Abstract

A synthetic strategy to provide two late-stage intermediates for the synthesis of diverse analogues of ROMK inhibitors for the treatment of hypertension and heart failure is described. Key transfor...

Published
2020
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results