422 results on '"Ekert, Paul"'
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2. Novel paediatric case of a spinal high-grade astrocytoma with piloid features in a patient with Noonan Syndrome
3. Author Correction: Functional precision medicine for pediatric cancers
4. Patient Experience of Complex Genomic Sequencing Exploring Patient Preference, Barriers, and Enablers for Delivery
5. Functional precision medicine for pediatric cancers
6. A novel transcriptional signature identifies T-cell infiltration in high-risk paediatric cancer
7. Histone H3-wild type diffuse midline gliomas with H3K27me3 loss are a distinct entity with exclusive EGFR or ACVR1 mutation and differential methylation of homeobox genes
8. Unusual PDGFRB fusion reveals novel mechanism of kinase activation in Ph-like B-ALL
9. Harnessing immune checkpoint trial data in pediatric cancer
10. Generation and multi-dimensional profiling of a childhood cancer cell line atlas defines new therapeutic opportunities
11. Ceramide-induced integrated stress response overcomes Bcl-2 inhibitor resistance in acute myeloid leukemia
12. Enhancer retargeting of CDX2 and UBTF::ATXN7L3 define a subtype of high-risk B-progenitor acute lymphoblastic leukemia
13. SFPQ-ABL1 and BCR-ABL1 use different signaling networks to drive B-cell acute lymphoblastic leukemia
14. JAFFAL: detecting fusion genes with long-read transcriptome sequencing
15. Precision-guided treatment in high-risk pediatric cancers
16. Whole-genome sequencing facilitates patient-specific quantitative PCR-based minimal residual disease monitoring in acute lymphoblastic leukaemia, neuroblastoma and Ewing sarcoma
17. Precision medicine and phosphoproteomics for the identification of novel targeted therapeutic avenues in sarcomas
18. Histone H3.3G34-Mutant Interneuron Progenitors Co-opt PDGFRA for Gliomagenesis
19. MLL-TFE3: a novel and aggressive KMT2A fusion identified in infant leukemia
20. Cotargeting BCL-2 and MCL-1 in high-risk B-ALL
21. The application of RNA sequencing for the diagnosis and genomic classification of pediatric acute lymphoblastic leukemia
22. In vitro and in vivo drug screens of tumor cells identify novel therapies for high‐risk child cancer
23. Immune profiling of pediatric solid tumors
24. Whole genome, transcriptome and methylome profiling enhances actionable target discovery in high-risk pediatric cancer
25. Efficacy of MEK inhibition in a recurrent malignant peripheral nerve sheath tumor
26. MINTIE: identifying novel structural and splice variants in transcriptomes using RNA-seq data
27. Diffuse leptomeningeal glioneuronal tumour (DLGNT) in children: the emerging role of genomic analysis
28. Reprogrammed CRISPR-Cas13b suppresses SARS-CoV-2 replication and circumvents its mutational escape through mismatch tolerance
29. A novel MYB::PAIP1 oncogenic fusion in pediatric blastic plasmacytoid dendritic cell neoplasm (BPDCN) is dependent on BCL2 expression and is sensitive to venetoclax
30. TALLSorts: a T-cell acute lymphoblastic leukemia subtype classifier using RNA-seq expression data
31. MicroRNA-155 expression and function in AML: An evolving paradigm
32. Human MLL/KMT2A gene exhibits a second breakpoint cluster region for recurrent MLL–USP2 fusions
33. 2011 – SUBCLONAL MUTATIONS ALTER CORE SIGNALLING NODES AND DRUG RESPONSES IN PAEDIATRIC ACUTE LYMPHOBLASTIC LEUKAEMIA
34. 3153 – CRISPR-DIRECTED CHROMOSOMAL TRANSLOCATIONS PROVIDE NOVEL INSIGHTS INTO LEUKEMIA BIOLOGY
35. Precision-guided treatment improves outcomes for children with high-risk cancers
36. Molecular principles of CRISPR-Cas13 mismatch intolerance enable selective silencing of point-mutated oncogenic RNA with single-base precision
37. Dysregulation of BCL-2 family proteins by leukemia fusion genes
38. High CD123 levels enhance proliferation in response to IL-3, but reduce chemotaxis by downregulating CXCR4 expression
39. Nano-targeted induction of dual ferroptotic mechanisms eradicates high-risk neuroblastoma
40. Germline HAVCR2 mutations altering TIM-3 characterize subcutaneous panniculitis-like T cell lymphomas with hemophagocytic lymphohistiocytic syndrome
41. Brief Report: Potent clinical and radiological response to larotrectinib in TRK fusion-driven high-grade glioma
42. Supplementary Tables S1-S7 from High-Throughput Drug Screening of Primary Tumor Cells Identifies Therapeutic Strategies for Treating Children with High-Risk Cancer
43. Data from High-Throughput Drug Screening of Primary Tumor Cells Identifies Therapeutic Strategies for Treating Children with High-Risk Cancer
44. Supplementary Figures and Figure Legends from High-Throughput Drug Screening of Primary Tumor Cells Identifies Therapeutic Strategies for Treating Children with High-Risk Cancer
45. Supplementary Materials and Methods from High-Throughput Drug Screening of Primary Tumor Cells Identifies Therapeutic Strategies for Treating Children with High-Risk Cancer
46. Supplementary Figures from High-Throughput Drug Screening of Primary Tumor Cells Identifies Therapeutic Strategies for Treating Children with High-Risk Cancer
47. Figure S7 from Distinct Assemblies of Heterodimeric Cytokine Receptors Govern Stemness Programs in Leukemia
48. Supplementary Table S2 from Distinct Assemblies of Heterodimeric Cytokine Receptors Govern Stemness Programs in Leukemia
49. Data from Distinct Assemblies of Heterodimeric Cytokine Receptors Govern Stemness Programs in Leukemia
50. SYST-15 GENERATION AND MULTI-DIMENSIONAL PROFILING OF A CHILDHOOD CANCER CELL LINE ATLAS DEFINES NEW THERAPEUTIC OPPORTUNITIES
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