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193 results on '"Edwards, Sean"'

1. An innovative in silico model of the oral mucosa reveals the impact of extracellular spaces on chemical permeation through epithelium

Author

Edwards, Sean M., Harding, Amy L., Leedale, Joseph A., Webb, Steve D., Colley, Helen E., Murdoch, Craig, and Bearon, Rachel N.

Subjects
Quantitative Biology - Tissues and Organs
Abstract

In pharmaceutical therapeutic design or toxicology, accurately predicting the permeation of chemicals through human epithelial tissues is crucial, where permeation is significantly influenced by the tissue's cellular architecture. Current mathematical models for multi-layered epithelium such as the oral mucosa only use simplistic 'bricks and mortar' geometries and therefore do not account for the complex cellular architecture of these tissues at the microscale level, such as the extensive plasma membrane convolutions that define the extracellular spaces between cells. Chemicals often permeate tissues via this paracellular route, meaning that permeation is underestimated. To address this, measurements of human buccal mucosal tissue were conducted to ascertain the width and tortuosity of extracellular spaces across the epithelium. Using mechanistic mathematical modelling, we show that the convoluted geometry of extracellular spaces significantly impacts chemical permeation and that this can be approximated, provided that extracellular tortuosity is accounted for. We next developed an advanced physically-relevant in silico model of oral mucosal chemical permeation using partial differential equations, fitted to chemical permeation in vitro assays on tissue-engineered human oral mucosa. Tissue geometries were measured and captured in silico, and permeation examined and predicted for chemicals with different physicochemical properties. The effect of altering the extracellular space to mimic permeation enhancers was also assessed by perturbing the in silico model. This novel in vitro-in silico approach has the potential to expedite pharmaceutical innovation for testing oromucosal chemical permeation, providing a more accurate, physiologically-relevant model which can reduce animal testing with early screening based on chemical properties.

Published
2024

2. Establishing African genomics and bioinformatics programs through annual regional workshops

Author

Sharaf, Abdoallah, Nesengani, Lucky Tendani, Hayah, Ichrak, Kuja, Josiah Ochieng, Mdyogolo, Sinebongo, Omotoriogun, Taiwo Crossby, Odogwu, Blessing Adanta, Beedessee, Girish, Smith, Rae Marvin, Barakat, Abdelhamid, Moila, Acclaim M., El Hamouchi, Adil, Benkahla, Alia, Boukteb, Amal, Elmouhtadi, Amine, Mafwila, Antoine Lusala, Abushady, Asmaa Mohammed, Elsherif, Assem Kadry, Ahmed, Bulbul, Wairuri, Charles, Ndiribe, Charlotte C., Ebuzome, Chukwuike, Kinnear, Craig J., Ndlovu, Deborah-Fay, Iraqi, Driss, El Fahime, Elmostafa, Assefa, Ermias, Ouardi, Faissal, Belharfi, Fatima Zohra, Tmimi, Fatim Zohra, Markey, Fatu Badiane, Radouani, Fouzia, Zeukeng, Francis, Mvumbi, Georges Lelo, Ganesan, Hamilton, Hanachi, Mariem, Nigussie, Helen, Charoute, Hicham, Benamri, Ichrak, Mkedder, Ikram, Haddadi, Imane, Meftah-Kadmiri, Issam, Mubiru, Jackson Franco, Domelevo Entfellner, Jean-Baka Kodjo, Rokani, Joan Bayowa, Ogwang, Joel, Daiga, Jude Bigoga, Omumbo, Judy, Ideozu, Justin Eze, Errafii, Khaoula, Labuschagne, Kim, Komi, Komi Koukoura, Tonfack, Libert Brice, Hadjeras, Lydia, Ramantswana, Madeleine, Chaisi, Mamohale, Botes, Marietjie W., Kilian, Mariëtte, Kvas, Marija, Melloul, Marouane, Chaouch, Melek, Khyatti, Meriem, Abdo, Michael, Phasha-Muchemenye, Mmatshepho, Hijri, Mohamed, Mediouni, Mohammed Rida, Hassan, Mohammed Ahmed, Piro, Mohammed, Mwale, Monica, Maaloum, Mossaab, Mavhunga, Mudzuli, Olivier, Nicholas Abraham, Aminou, Oumaima, Arbani, Oumayma, Souiai, Oussema, Djocgoue, Pierre François, Mentag, Rachid, Zipfel, Renate Dorothea, Tata, Rolland Bantar, Megnekou, Rosette, Muzemil, Sadik, Paez, Sadye, Salifu, Samson Pandam, Kagame, Samuel Paul, Selka, Sarra, Edwards, Sean, Gaouar, Semir Bechir Suheil, Reda, Shaimaa Roshdy Abdullah, Fellahi, Siham, Khayi, Slimane, Ayed, Soumia, Madisha, Thabang, Sahil, Tulsi, Udensi, Ogbuagu Ugorji, Ras, Verena, Ezebuiro, Victor, Duru, Vincent C., David, Xavier, Geberemichael, Yonas, Tchiechoua, Yves H., Mungloo-Dilmohamud, Zahra, Chen, Zhiliang, Happi, Christian, Kariuki, Thomas, Ziyomo, Cathrine, Djikeng, Appolinaire, Badaoui, Bouabid, Mapholi, Ntanganedzeni, Muigai, Anne, Osuji, Julian O., and Ebenezer, ThankGod Echezona

Published
2024
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5. Thermally driven three-dimensional flows and their stability

Author

Edwards, Sean, Duck, Peter, and Hewitt, Richard

Subjects
Asymptotic analysis, Scientific computing, Object-oriented programming, Convection, Boussinesq approximation, Flat-plate, Stability, Buoyancy, Finite-difference methods, Corner boundary layers, Boundary-region equations, Parabolised stability equations, Three-dimensional boundary layers, Applied Mathematics, Crank-Nicolson method
Abstract

This thesis focuses on three-dimensional thermally-driven boundary layers with three distinct types of (steady) thermal forcing (i) a streamwise-aligned heat source that is spanwise localised, (ii) a spanwise and streamwise localised heat source and (iii) a non-localised globally driven natural convection problem. What ties these problems together is that the induced three-dimensionality is on a spanwise lengthscale commensurate with the boundary-layer thickness, and so their leading-order flow is governed by the 'boundary-region' equations, attributed to Kemp (1951). A lot of work has been undertaken within this boundary-region framework in an isothermal context, for example forced by injection or roughness, but presently there has been limited work in which temperature variation has been applied. In our first problem (i), we embed a streamwise-aligned spanwise-localised heated strip, which has an O(Re^(-1/2)) spanwise scale, in a horizontal semi-infinite flat plate. At large spanwise distances from the forcing region, the flow takes the form of the two-dimensional Falkner--Skan boundary layer (1930). The three-dimensional flow response is determined numerically and a robust streak-roll structure forms downstream. We undertake an asymptotic analysis at large streamwise coordinates, and obtain the downstream transverse growth of the nonlinear response. We also determine the flow over a streamwise-aligned injection slot, and make qualitative comparisons with the thermally forced problem. A localised heat source with an O(1) streamwise scale and an O(Re^(-1/2)) spanwise scale is then considered (ii), and the corresponding nonlinear problem is solved. For weak thermal forcing, the isolated heated region results in a downstream response which has an algebraically developing velocity field. By seeking a linear bi-global eigenvalue problem in terms of the downstream algebraic spatial growth, we show that there is a new class of linear spanwise-localised algebraically developing disturbances in the Falkner--Skan boundary layer when thermal effects are included. The velocity field of the dominant mode grows (algebraically) downstream, and is driven by a decaying (weak) temperature field. Above a critical pressure gradient the dominant mode decays, and we determine the critical Prandtl number and pressure gradient parameter for downstream algebraic growth. The linear algebraically growing response ultimately gives rise to a nonlinear spanwise-localised streak-roll response downstream. We assess the stability of the streak response to time-harmonic (viscous) disturbances and inviscid Rayleigh modes. Our third problem (iii) is the natural convection flow in a heated vertical corner. This is a globally driven, non-localised problem, however in a high Grashof number regime the flow in a region near to the corner is governed by the boundary-region equations. Two self-similar solutions are determined: (A) a solution first discussed by Riley and Poots (1972), and (B) a new solution which, at large spanwise coordinates, has a coupled linearly-developing crossflow component. We show that the streamwise velocity and temperature fields determined by Riley and Poots (1972) for solution A were surprisingly accurate, given that their computational resources were limited. However, they concluded that there is an in-plane flow away from the corner which is not present in the properly resolved solution. The non-parallel stability of the self-similar profiles is tackled with the parabolised stability equations (PSE).

Published
2022

8. I'm Here; I'm Queer: How One Parent Advocates for the Inclusion of Queer Youth

Author

Colvin, Kody, Edwards, Sean, and Eng, Britnee

Abstract

Educators and school administration are tasked with creating schools that support and affirm LGBTQ+ (lesbian, gay, bisexual, transgender, and queer) students and families. This study explores a high school in a conservative community as one parent attempts to advocate for their transgender child and other LGBTQ+-identifying students. Although school employees are mandated by state and federal laws to ensure that all students are free from bullying and harassment, the research highlights that schools remain hostile for many LGBTQ+ students. This article provides reflection questions throughout the case as a way for school leadership to grapple with and challenge their thinking regarding LGBTQ+-affirming strategies in their schools.

Published
2022
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19. Contributors

Author

Buras, Eric Dale, primary, Choksi, Palak, additional, Clines, Gregory A., additional, Cooke-Hubley, Sandra, additional, Crisologo, Peter A., additional, Edwards, Sean P., additional, Haase, Steven C., additional, Hooper, Rachel C., additional, Kashyap, Sangeeta R., additional, Kheniser, Karim G., additional, Kovacs, Christopher S., additional, La Fontaine, Javier, additional, Lee, Pearl G., additional, Mizokami-Stout, Kara, additional, Ognenovski, Vladimir, additional, Oh, Tae-Ju, additional, Reddy, S. Sethu K., additional, Ruggiero, Brian L., additional, Schmidt, Brian M., additional, Subauste, Angela, additional, Subauste, Jose S., additional, Tan, MengHee, additional, Teng, Gim Gee, additional, Teo, Desmond B., additional, Valderrábano, Rodrigo J., additional, and Yu, Shan-Huey, additional

Published
2020
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24. Using Video Modeling and Video Prompting to Teach Core Academic Content to Students with Learning Disabilities

Author

Kellems, Ryan O. and Edwards, Sean

Abstract

Practitioners are constantly searching for evidence-based practices that are effective in teaching academic skills to students with learning disabilities (LD). Video modeling (VM) and video prompting have become popular instructional interventions for many students across a wide range of different disability classifications, including those with LD. This article provides readers with the knowledge necessary to understand VM, and includes directions and resources needed to implement an academic VM intervention for a student with LD.

Published
2016
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28. Contributors

Author

Al-Qamachi, Laith, primary, Amarasinghe, Hemantha K., additional, Andersen, Peter E., additional, Arce, Kevin, additional, Arya, Varun, additional, Avraham, Tomer, additional, Bakst, Richard L., additional, Basile, Lauren E., additional, Beckler, Andrew D., additional, Bell, R. Bryan, additional, Bhuta, Sandeep, additional, Bifulco, Carlo B., additional, Bittermann, Gido, additional, Blackwell, Keith E., additional, Blanco, Angel, additional, Bobinskas, Alexander M., additional, Brammer, Caroline, additional, Brecht, Lawrence E., additional, Brown, James, additional, Butterworth, Chris J., additional, Carlson, Eric R., additional, Chadwick, Keith A., additional, Chandra, Srinivasa R., additional, Cheng, Allen, additional, Claiborne, Scott, additional, Clayburgh, Daniel R., additional, Crittenden, Marka R., additional, Curti, Brendan D., additional, Dafydd, Derfel ap, additional, Dagan, Roi, additional, Dawson, Camilla, additional, Dierks, Eric J., additional, Dillon, Jasjit K., additional, Dyalram, Donita, additional, Edwards, Sean P., additional, Elliott, David A., additional, Evans, Mererid, additional, Fagin, Adam P., additional, Fakhry, Carole, additional, Faries, Mark B., additional, Feng, Zipei, additional, Fernandes, Rui P., additional, Ferrell, Jay K., additional, Fox, Bernard A., additional, Fuller, Clifton D., additional, Ghali, G.E., additional, Gleysteen, John P., additional, Gold, Kathryn A., additional, Good, James, additional, Grandis, Jennifer R., additional, Graville, Donna J., additional, Gross, Neil D., additional, Grossberg, Aaron, additional, Guo, Shan, additional, Hamilton, Bronwyn, additional, Hansen, Eric K., additional, Hansen, Heidi J., additional, Haughey, Bruce H., additional, Hayden, Richard E., additional, Helman, Joseph I., additional, Hirsch, David L., additional, Holland, John M., additional, Hutcheson, Katherine A., additional, Hyers, Megan J., additional, Idle, Matthew, additional, Jackson, James E., additional, Jalisi, Scharukh, additional, Johnson, Newell W., additional, Jones, Terry M., additional, Kademani, Deepak, additional, Kelley, Joseph R., additional, Kerawala, Cyrus, additional, Kim, Dongsoo David, additional, Kotz, Tamar A., additional, Kuno, Hirofumi, additional, Kuriakose, Moni Abraham, additional, Langmore, Susan E., additional, Leidner, Rom, additional, Levine, Jamie P., additional, Loh, Christopher, additional, Lohiya, Sapna, additional, Lubek, Joshua E., additional, Lyons, Andrew J., additional, Marruffo, Joann, additional, Marx, Robert E., additional, Matos, Marco, additional, Mattox, Austin, additional, Mehrotra, Avanti, additional, Melville, James C., additional, Metzger, Marc C., additional, Miles, Brett A., additional, Misiukiewicz, Krzysztof J., additional, Mohamed, Abdallah S.R., additional, Monaco, Casian, additional, Murphy, James, additional, Nabavizadeh, Nima, additional, Nadershah, Mohammed, additional, Nagel, Thomas H., additional, Newbold, Kate, additional, Nikolarakos, Dimitrios, additional, Nisi, Kurt, additional, Ord, Robert A., additional, Over, Larry M., additional, Pai, Sara I., additional, Palmer, Andrew D., additional, Parmar, Sat, additional, Patel, Ashish A., additional, Patel, Ketan, additional, Patterson, JoanneM., additional, Petrisor, Daniel, additional, Pirgousis, Phillip, additional, Qualliotine, Jesse R., additional, Riva, Francesco M.G., additional, Rubin, Samuel J., additional, Sakai, Osamu, additional, Salama, Andrew, additional, Schindler, Joshua S., additional, Schmelzeisen, Rainer, additional, Seung, Steven K., additional, Shum, Jonathan, additional, Sim, Felix, additional, Smart, Ryan J., additional, Stranix, John T., additional, Subramanian, Janakiraman, additional, Suntharalingam, Mohan, additional, Thankappan, Krishnakumar, additional, Thomas, James Phillip, additional, Tighe, David, additional, Tolba, Khaled A., additional, Troob, Scott H., additional, Truong, Minh Tam, additional, Tursun, Ramzey, additional, Ward, Brent B., additional, Watters, Amber L., additional, Wax, Mark K., additional, Webster, Richard M., additional, Weinberg, Andrew, additional, Xiao, Hong D., additional, Yildirim, Yavuz, additional, and Ying, Yedeh, additional

Published
2018
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35. Contributors

Author

Abubaker, A. Omar, Acero, Julio, Agarwal, Ravi, Aghaloo, Tara, Akbari, Maryam, Allen, Kyle P., Allon, Dror M., Almeida, Fernando, Alpert, Brian, Altay, Mehmet Ali, Amarista, Felix Jose, Amer, Hatem, Appugounder, Suganya, Aravindaksha, Shyam Prasad, Aronovich, Sharon, Assael, Leon, Awadallah, Michael, Aziz, Shahid R., Bagheri, Shahrokh C., Bailey, Jonathan, Baker, Andrew M., Bakri, Karim, Barnes, Suzanne, Bast, Brian, Batal, Hussam, Baur, Dale A., Bedrossian, Edmond, Bedrossian, Edmond Armand, Bell, R. Bryan, Bitonti, David A., Bohluli, Behnam, Bonin, Genevieve C., Bouloux, Gary F., Bradley, Meaghan, Breik, Omar, Brockhoff, Hans C., II, Buchbinder, Daniel, Bui, Tuan G., Byrne, Patrick, Caccamese, John Francis, Jr, Caloss, Ron, Caplin, Courtney, Carlson, Eric R., Casap, Nardy, Hill, Carrie E. Cera, Chakrabarti, Swagnik, Chandran, Ravi, Chaney, Blake, Cheng, Allen C., Chigurupati, Radhika, Cho, Nam, Chou, Joli, Christensen, Louis J., Cillo, Joseph E., Jr, Claiborne, Scott T., Collette, David, Contasti-Bocco, Gisela, Costello, Bernard J., Cotofana, Sebastian, Couey, Marcus A., Cunningham, Larry, Jr, Curtis, William J., L. Cuzalina, Angelo, Dang, Rushil R., Daniel, Renie, Dattilo, David J., Dean, Jeffrey S., Desai, Shaun C., Dillon, Jasjit K., Doucet, Jean-Charles, Drew, Stephanie Joy, Dyalram, Donita, Edwards, Sean P., Emam, Hany, Emmerling, Max R., Engelstad, Mark, Erickson, Helaman, Evasovich, Maria, Fagin, Adam P., Fanelli, Christopher A., Fantuzzo, Joseph J., Fattahi, Tirbod, Fernandes, Rui P., Finn, Richard Allen, Franco, Peter B., Gailey, David, Gangwani, Pooja, Ghali, Ghali E., Gibreel, Waleed, Girod, Sabine C., Golden, Brent, Gonzalez, Jorge, Gonzalez, Marianela, Granquist, Eric J., Grant, Jaime, Gray, Mingyang Liu, Guerrero, Cesar A., Hadaya, Danny, Hamlar, David, Hammer, Daniel A., Hanba, Curtis, Heggie, Andrew Alistair, Henriquez, Mariana, Henry, Andrew, Herford, Alan S., Herman, Brandyn, Hinkl, David, Holmes, Anthony David, Holton, James B., Hossaini-Zadeh, Mehran, Hossameldin, Reem H., Hsieh, Tsung-yen, Huang, Allen, Hughes, Pamela J., Hutchinson, Tanisha, Idle, Matthew R., Sunder Indrakanti, Shyam, Jaskolka, Michael, Jelmini, Jonathan James, Jensen, Ole T., Jethwa, Ashok R., Jones, Baxter, Kademani, Deepak, Kang, David R., Kao, Herman, Karlis, Vasiliki, Kim, Beomjune, Kim, D. David, Kim, Roderick Y., Kloostra, Paul, Kolokythas, Antonia, Koppel, David A., Krishnan, Deepak G., Kuriakose, Moni A., Lai, Li Han, Laster, Zvi, Laviv, Amir, Lee, Andrew W.C., Lewallen, James B., Yung-Chuan Liu, Stanley, Loetscher, Christian A., Louis, Patrick J., Lubek, Joshua E., Lugo, Ricardo, Lyford-Pike, Sofia, Kushner, George M., MacIver, Colin, MacLeod, Stephen P.R., Magraw, Caitlin B.L., Makhoul, Nicholas M., Manlove, Ashley E., Mardini, Samir, Markiewicz, Michael R., Marschall, Jeffrey S., Matthews, Nigel Shaun, McCain, Joseph P., McCoy, J. Michael, McKenna, Samuel J., Meara, Daniel J., Medeiros, Paulo Jose, Mehra, Pushkar, Mercuri, Louis G., Miles, Brett A., Miller, Meagan, Moe, Justine, Moon, Hwi Sean, Silva, Marina Morante, Morris, Christopher, Morton, Dean, Movahed, Reza, Mujica, Elena, Nadeau, Robert, Nathan, John M., Ness, Gregory M., Norbutt, Craig, Nuveen, Erik Jon, Obeid, George, Okay, Devin Joseph, Olivieri, Petra, Ord, Robert, Oreadi, Daniel, Panchal, Neeraj, Parmar, Sat, Patel, Ashish A., Peacock, Zachary S., Pennau, Karl, Perciaccante, Vincent J., Perenack, Jon D., Petukhova, Yuliya, Pfeiffer, Laurence D., Pham, Matthew H., Phelan, John N., Pi-Anfruns, Joan, Pierce, Brendan H.G., Pinkston, Daniel Joseph, Polido, Waldemar D., Posnick, Jeffrey C., Powers, David B., Prange-Kiel, Janine, Praveen, Prav, Precious, David S., Quereshy, Faisal A., Quinn, Peter D., Radant, Matthew, Ray, Christopher K., Read-Fuller, Andrew, Reddy, Likith, Renapurkar, Shravan, Reyneke, Johan P., Ritto, Fabio G., Robertson, Carrie E., Rogers, Jason, Ruggiero, Brian Louis, Ruiz, Ramon L., Sabino, Mary Ann C., Sabooree, Sepideh, Salama, Andrew, Salinas, Thomas J., Samman, Nabil, Sauerbier, Sebastian, Schlieve, Thomas, Schlissel, Edward R., Schmelzeisen, Rainer, Shand, Jocelyn M., Sharma, Kaushik H., Shirley, Brett, Shivers, Paul, Shupak, Raymond P., Van Sickels, Joseph E., Sinn, Douglas P., Smith, Kevin, Smith, Miller H., Soletic, Luke C., Stanek, Joel, Stanton, David, Steed, Martin B., Stevens, Mark, Suchyta, Marissa, Sullivan, Steven M., Sulyman, Omotara, Susarla, Srinivas M., Sylvester, David Knight, II, Talmant, Jean-Claude, Tandon, Rahul, Thakker, Jayini, Thayer, Stone, Tiwana, Paul S., Tolomeo, Pasquale G., Tran, Dan Q., Treasure, Trevor E., Trent, David C., Triplett, R. Gilbert, Tull, Greg, Turner, Michael D., Turvey, Timothy A., Uppgaard, Rachel, Vigliante, Craig E., Viozzi, Christopher F., Vorrasi, John, Waite, Peter D., Wan, Kenneth, Ward, Brent B., Wentland, Todd R., Williams, Fayette C., Woerner, Jennifer E., Wolford, Larry M., Wong, Patrick, Woo, Brian M., Wrzosek, Mariusz K., Yamashita, Duke, Yates, David M., Yeoh, Melvyn, Ying, Yedeh, Zakhary, George, and Zuniga, John R.

Published
2024
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40. Clinical Practice Trends and Postoperative Outcomes in Primary Cleft Rhinoplasty.

Author

Jazayeri, Hossein E., Lopez, Joseph, Pourtaheri, Navid, Lee, Kevin C., Peck, Connor J., Best, David L., Yu, Jason W., Gosain, Arun K., Peacock, Zachary S., Edwards, Sean P., and Steinbacher, Derek M.

Subjects
RHINOPLASTY, LENGTH of stay in hospitals, MULTIPLE regression analysis, MEDICAL care costs, SURGICAL complications, RETROSPECTIVE studies, CLEFT lip, T-test (Statistics), TREATMENT effectiveness, POSTOPERATIVE period, DESCRIPTIVE statistics, CHI-squared test, PHYSICIAN practice patterns
Abstract

Purpose: Optimal correction of the cleft nasal deformity remains challenging. The purpose of this study was to examine the practice patterns and postoperative course of patients undergoing cleft lip repair with rhinoplasty compared to those who have primary lip repair without rhinoplasty. Methods and Materials: A retrospective cohort study was conducted based on the Kids' Inpatient Database. Data were collected from January 2000 to December 2011 and included infants aged 12 months and younger who underwent cleft lip repair. The predictor variable was the addition of rhinoplasty at primary cleft lip repair. Primary outcome variables included hospital setting, year, and admission cost, while secondary outcome variables included length of stay and postoperative complication rate. Independent t -tests and chi-squared tests were performed. Continuous variables were analyzed by multiple linear regression models. Results: The study sample included 4559 infants with 1422 (31.2%) who underwent primary cleft rhinoplasty. Over time, there was a significant increase in the proportion of cleft lip repairs accompanied by a rhinoplasty (p <.01). A greater proportion of patients with unilateral cleft lips received simultaneous rhinoplasty with their lip repairs (33.8 vs 26.0%, p <.01). This cohort had a significantly shorter length of stay (1.6 vs 2.8 days, p <.01) when compared to children that underwent cleft lip repair alone. Conclusions: Performing primary cleft rhinoplasty is becoming more common among cleft surgeons. Considering comparable costs and complication rates, a rhinoplasty should be considered during the surgical treatment planning of patients with cleft nasal deformities. [ABSTRACT FROM AUTHOR]

Published
2022
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48. I'm Here; I'm Queer: How One Parent Advocates for the Inclusion of Queer Youth.

Author

Colvin, Kody, Edwards, Sean, and Eng, Britnee

Subjects
LGBTQ+ youth, LGBTQ+ students, TRANSGENDER children, EDUCATIONAL leadership, SCHOOL employees
Abstract

Educators and school administration are tasked with creating schools that support and affirm LGBTQ+ (lesbian, gay, bisexual, transgender, and queer) students and families. This study explores a high school in a conservative community as one parent attempts to advocate for their transgender child and other LGBTQ+-identifying students. Although school employees are mandated by state and federal laws to ensure that all students are free from bullying and harassment, the research highlights that schools remain hostile for many LGBTQ+ students. This article provides reflection questions throughout the case as a way for school leadership to grapple with and challenge their thinking regarding LGBTQ+-affirming strategies in their schools. [ABSTRACT FROM AUTHOR]

Published
2022
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49. Management of Complications Associated With Gorham-Stout Disease: Case Report and Review of the Literature.

Author

Goncalves, Paulo Zupelari, Shelgikar, Anita, Edwards, Sean, Stanley, Jeffrey, and Aronovich, Sharon

Subjects
GORHAM'S disease, SURGICAL complications, AIRWAY (Anatomy), SLEEP apnea syndromes, CARDIAC arrest
Abstract

This case report describes the course of a patient diagnosed with Gorham-Stout Disease and reviews known complications and treatment options for this rare condition. An emphasis is placed on potential multi-systemic complications that may occur including surgical complications, obstructive sleep apnea, post-operative airway obstruction, respiratory failure and cardiac arrest. [ABSTRACT FROM AUTHOR]

Published
2022
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