214 results on '"Economides, Aris N"'
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2. Converging evidence from exome sequencing and common variants implicates target genes for osteoporosis
3. Odd skipped-related 1 controls the pro-regenerative response of fibro-adipogenic progenitors
4. Sequencing of 640,000 exomes identifies GPR75 variants associated with protection from obesity
5. Antibodies to sclerostin or G-CSF receptor partially eliminate bone or marrow adipocyte loss, respectively, following vertical sleeve gastrectomy
6. Regulation of sensorimotor gating via Disc1/Huntingtin-mediated Bdnf transport in the cortico-striatal circuit
7. Multiancestry exome sequencing reveals INHBE mutations associated with favorable fat distribution and protection from diabetes
8. Comparative Transcriptomics Identifies Novel Genes and Pathways Involved in Post-Traumatic Osteoarthritis Development and Progression.
9. SOST/Sclerostin Improves Posttraumatic Osteoarthritis and Inhibits MMP2/3 Expression After Injury
10. Global molecular changes in a tibial compression induced ACL rupture model of post‐traumatic osteoarthritis
11. Wnt co-receptors Lrp5 and Lrp6 differentially mediate Wnt3a signaling in osteoblasts
12. Noncoding RNA processing by DIS3 regulates chromosomal architecture and somatic hypermutation in B cells
13. Activin A does not drive post-traumatic heterotopic ossification
14. Lysosomal degradation of ACVR1-Activin complexes negatively regulates signaling of Activins and Bone Morphogenetic Proteins
15. How Activin A Became a Therapeutic Target in Fibrodysplasia Ossificans Progressiva
16. Sostdc1 deficiency accelerates fracture healing by promoting the expansion of periosteal mesenchymal stem cells.
17. Sclerostin antibody treatment improves fracture outcomes in a Type I diabetic mouse model
18. Structural characterization of an activin class ternary receptor complex reveals a third paradigm for receptor specificity
19. Anti-ACVRI antibodies exacerbate heterotopic ossification in fibrodysplasia ossificans progressive (FOP) by activating FOP-mutant ACVR1
20. THU402 New Heterotopic Ossification Lesions In Patients With Fibrodysplasia Ossificans Progressiva Measured By PET/CT vs CT Only
21. OR29-06 Flare-Ups In Patients With Fibrodysplasia Ossificans Progressiva Reduced By Garetosmab Treatment: LUMINA-1 Data
22. Skeletal phenotype amelioration in Mucopolysaccharidosis VI requires intervention at the earliest stages of postnatal development
23. Context-dependent functions of angiopoietin 2 are determined by the endothelial phosphatase VEPTP
24. Induction of the Hajdu-Cheney Syndrome Mutation in CD19 B Cells in Mice Alters B-Cell Allocation but Not Skeletal Homeostasis
25. The obligatory role of Activin A in the formation of heterotopic bone in Fibrodysplasia Ossificans Progressiva
26. Activin E–ACVR1C cross talk controls energy storage via suppression of adipose lipolysis in mice
27. Sostdc1 deficiency accelerates fracture healing by promoting the expansion of periosteal mesenchymal stem cells
28. Sclerostin antibody treatment improves fracture outcomes in a Type I diabetic mouse model
29. Garetosmab, an inhibitor of activin A, reduces heterotopic ossification and flare-ups in adults with fibrodysplasia ossificans progressiva: a randomized, double-blind, placebo-controlled phase 2 trial
30. TMPRSS6 Inhibition with a Monoclonal Antibody Improves Red Blood Cell Health and Reduces Hepatic Iron Loading in Mouse Models of Iron Overload Diseases
31. Inhibition of leukemia cell engraftment and disease progression in mice by osteoblasts
32. Odd skipped-related 1 controls the pro-regenerative response of Fibro-Adipogenic Progenitors
33. Liver-specific AAV gene therapy corrects lipid storage in LAL-D model mice but does not prevent lipid accumulation in acquired fatty liver model mice
34. Cell type-selective targeted delivery of a recombinant lysosomal enzyme for enzyme therapies
35. A lymphatic defect causes ocular hypertension and glaucoma in mice
36. ACVR1 antibodies exacerbate heterotopic ossification in fibrodysplasia ossificans progressiva (FOP) by activating FOP-mutant ACVR1
37. Garetosmab Reduces Flare-ups in Patients With Fibrodysplasia Ossificans Progressiva
38. Saracatinib is an efficacious clinical candidate for fibrodysplasia ossificans progressiva
39. Anti-GDF11Treatment of β-Thalassemia Intermedia Mice Does Not Improve Erythropoiesis
40. Saracatinib is an efficacious clinical candidate for fibrodysplasia ossificans progressiva
41. NMIHBA results from hypomorphic PRUNE1 variants that lack short-chain exopolyphosphatase activity
42. Activin A forms a non-signaling complex with ACVR1 and type II Activin/BMP receptors via its finger 2 tip loop
43. Author response: Activin A forms a non-signaling complex with ACVR1 and type II Activin/BMP receptors via its finger 2 tip loop
44. Targeted delivery of acid alpha-glucosidase corrects skeletal muscle phenotypes in Pompe disease mice
45. Effects of BMP7 produced by group 2 innate lymphoid cells on adipogenesis
46. Functional modeling of NMIHBA-causingPRUNE1variants reveals a requirement for its exopolyphosphatase activity
47. Odd skipped-related 1 (Osr1) identifies muscle-interstitial fibro-adipogenic progenitors (FAPs) activated by acute injury
48. The finger 2 tip loop of Activin A is required for the formation of its non-signaling complex with ACVR1 and type II Bone Morphogenetic Protein receptors
49. Multifunctional Alleles: A novel method for the generation of “All-In-One” null and conditional alleles
50. The cortico-striatal circuit regulates sensorimotor gating via Disc1/Huntingtin-mediated Bdnf transport
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