19 results on '"Dutra, Jason K."'
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2. Structural basis of the acyl-transfer mechanism of human GPAT1
3. Mechanistic differences between linear vs. spirocyclic dialkyldiazirine probes for photoaffinity labeling.
4. Structural basis of the acyl-transfer mechanism of human GPAT1
5. Fluorophosphonates on‐Demand: A General and Simplified Approach toward Fluorophosphonate Synthesis
6. Fluorophosphonate‐Based Degrader Identifies Degradable Serine Hydrolases by Quantitative Proteomics
7. SuFEx Activation with Ca(NTf2)2: A Unified Strategy to Access Sulfamides, Sulfamates, and Sulfonamides from S(VI) Fluorides
8. Pharmacological evaluation of clinically relevant concentrations of (2R,6R)-hydroxynorketamine
9. Quantitative Analysis of 18F-PF-06684511, a Novel PET Radioligand for Selective β-Secretase 1 Imaging, in Nonhuman Primate Brain
10. Design and Synthesis of Clinical Candidate PF-06751979: A Potent, Brain Penetrant, β-Site Amyloid Precursor Protein Cleaving Enzyme 1 (BACE1) Inhibitor Lacking Hypopigmentation
11. Identification of a Novel Positron Emission Tomography (PET) Ligand for Imaging β-Site Amyloid Precursor Protein Cleaving Enzyme 1 (BACE-1) in Brain
12. Trifluoromethyl Oxetanes: Synthesis and Evaluation as a tert -Butyl Isostere
13. Quantitative Analysis of 18F-PF-06684511, a Novel PET Radioligand for Selective β-Secretase 1 Imaging, in Nonhuman Primate Brain.
14. Design and Synthesis of Clinical Candidate PF-06751979: A Potent, Brain Penetrant, β-Site Amyloid Precursor Protein Cleaving Enzyme 1 (BACE1) Inhibitor Lacking Hypopigmentation.
15. Identification of a Novel Positron Emission Tomography (PET) Ligand for Imaging β-Site Amyloid Precursor Protein Cleaving Enzyme 1 (BACE-1) in Brain.
16. Discovery of a Series of Efficient, Centrally Efficacious BACE1 Inhibitors through Structure-Based Drug Design
17. Discovery of a Series of Efficient,Centrally EfficaciousBACE1 Inhibitors through Structure-Based Drug Design.
18. SuFEx Activation with Ca(NTf 2 ) 2 : A Unified Strategy to Access Sulfamides, Sulfamates, and Sulfonamides from S(VI) Fluorides.
19. Quantitative Analysis of 18 F-PF-06684511, a Novel PET Radioligand for Selective β-Secretase 1 Imaging, in Nonhuman Primate Brain.
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