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5 results on '"Diolez J"'

3. Carfilzomib weekly 20/56 mg/m 2 , lenalidomide and dexamethasone for early relapsed refractory multiple myeloma.

Author

Richez V, Gruchet C, Guidez S, Fouquet G, Azais I, Durand G, Javaugue V, Brigaud A, Plasse F, Diolez J, Machet A, Moya N, Gardeney H, Franques P, Bobin A, Levy A, Sabirou F, Bonnin A, Dieval C, Primault S, Barrier J, Fleck E, Bouyier S, Daras C, Princet I, Bauwens D, Legros L, Fuzibet JG, Gil A, Bridoux F, Avet-Loiseau H, and Leleu X

Subjects
Aged, Aged, 80 and over, Dexamethasone administration & dosage, Drug Administration Schedule, Female, Humans, Kaplan-Meier Estimate, Lenalidomide administration & dosage, Male, Middle Aged, Oligopeptides administration & dosage, Progression-Free Survival, Recurrence, Salvage Therapy, Antineoplastic Combined Chemotherapy Protocols therapeutic use, Multiple Myeloma drug therapy
Published
2019
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4. Comparison of hemodialysis with medium cut-off dialyzer and on-line hemodiafiltration on the removal of small and middle-sized molecules
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Author

Belmouaz M, Diolez J, Bauwens M, Duthe F, Ecotiere L, Desport E, and Bridoux F

Subjects
Creatinine analysis, Humans, Retrospective Studies, Urea analysis, beta 2-Microglobulin analysis, Hemodiafiltration instrumentation, Hemodiafiltration methods, Hemodiafiltration statistics & numerical data, Renal Dialysis instrumentation, Renal Dialysis methods, Renal Dialysis statistics & numerical data
Abstract

Background: Recent data suggest that the use of medium cut-off (MCO) dialyzers in hemodialysis (HD) promotes greater clearance and reduction ratio (RR) for myoglobin and other large-sized molecules than on-line hemodiafiltration (ol-HDF), but its effects on β2-microglobulin are not clear. We compared RR and clearances of small and middle-sized molecules between high-flux ol-HDF and MCO (Theranova) dialyzer in HD (MCO-HD) as well as nutritional parameters., Materials and Methods: We retrospectively analyzed 10 patients treated first with ol-HDF who were thereafter switched to MCO-HD over a 1-year period. Three dialysis sessions in each 6-month period were examined. We calculated RR and clearance of small and middle-sized molecules., Results: There was no significant difference between ol-HDF and MCO-HD for median serum albumin and prealbumin level, mean KT/V, mean urea and creatinine RR, mean β2-microglobulin (81 ± 5 vs. 81 ± 6%, p = 0.72) and myoglobin (60 ± 9% vs. 61 ± 7%, p = 0.59), RR or clearances., Conclusion: The use of MCO (Theranova) dialyzer in HD produces similar removal of urea, creatinine, β2-microglobulin and myoglobin as does ol-HDF, with good tolerance profile and without modification of nutritional status.
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Published
2018
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5. Pilot Pharmacokinetic Study of High-Dose Daptomycin in Hemodialysis Patients With Infected Medical Devices.

Author

Diolez J, Venisse N, Belmouaz S, Bauwens MA, Bridoux F, and Beraud G

Subjects
Aged, Anti-Bacterial Agents administration & dosage, Anti-Bacterial Agents pharmacokinetics, Bacterial Infections etiology, Bacterial Infections metabolism, Catheter-Related Infections etiology, Daptomycin administration & dosage, Dose-Response Relationship, Drug, Female, Humans, Male, Middle Aged, Pilot Projects, Prospective Studies, Renal Dialysis adverse effects, Bacterial Infections drug therapy, Catheter-Related Infections drug therapy, Daptomycin pharmacokinetics, Renal Dialysis instrumentation
Published
2017
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