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Your search keyword '"D. Cussol"' showing total 7 results
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7 results on '"D. Cussol"'

1. Cross section measurements for production of positron emitters for PET imaging in carbon therapy

Author

J.M. Fontbonne, J. Colin, M. Labalme, S. Salvador, D. Cussol, C. Divay, Laboratoire de physique corpusculaire de Caen (LPCC), Université de Caen Normandie (UNICAEN), Normandie Université (NU)-Normandie Université (NU)-École Nationale Supérieure d'Ingénieurs de Caen (ENSICAEN), Normandie Université (NU)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3), Normandie Université (NU)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Laboratoire de physique corpusculaire de Caen ( LPCC ), Université de Caen Normandie ( UNICAEN ), Normandie Université ( NU ) -Normandie Université ( NU ) -Ecole Nationale Supérieure d'Ingénieurs de Caen ( ENSICAEN ), and Normandie Université ( NU ) -Institut National de Physique Nucléaire et de Physique des Particules du CNRS ( IN2P3 ) -Centre National de la Recherche Scientifique ( CNRS )

Subjects
medicine.medical_specialty, Ion beam, Monte Carlo method, [SDV.IB.MN]Life Sciences [q-bio]/Bioengineering/Nuclear medicine, [PHYS.NEXP]Physics [physics]/Nuclear Experiment [nucl-ex], 01 natural sciences, 030218 nuclear medicine & medical imaging, Ion, Nuclear physics, 03 medical and health sciences, 0302 clinical medicine, Positron, Fragmentation (mass spectrometry), 0103 physical sciences, medicine, Medical physics, [ PHYS.NEXP ] Physics [physics]/Nuclear Experiment [nucl-ex], Nuclear Experiment, Common emitter, Physics, medicine.diagnostic_test, 010308 nuclear & particles physics, Positron emission tomography, [PHYS.PHYS.PHYS-MED-PH]Physics [physics]/Physics [physics]/Medical Physics [physics.med-ph], Physics::Accelerator Physics, Nucleon
Abstract

International audience; In light ion beam therapy, positron (β+) emitters are produced by the tissue nuclei through nuclear interactions with the beam ions. They can be used for the verification of the delivered dose using positron emission tomography by comparing the spatial distribution of the β+ emitters activity to a computer simulation taking into account the patient morphology and the treatment plan. However, the accuracy of the simulation greatly depends on the method used to generate the nuclear interactions producing these emitters. In the case of Monte Carlo (MC) simulations, the nuclear interaction models still lack the required accuracy due to insufficient experimental cross section data. This is particularly true for carbon therapy where literature data on fragmentation cross sections of a carbon beam with targets of medical interest are very scarce. Therefore, we performed at GANIL in July 2016 measurements on β+ emitter production cross sections with a carbon beam at 25, 50, and 95 MeV/nucleon on thin targets (C, N, O, and PMMA). We extracted the production cross section of C10,11, N13, and O14,15 that are essential to constrain or develop MC nuclear fragmentation models.

Published
2017

2. Differential cross section measurements for hadron therapy: 50 MeV/nucleon C12 reactions on H, C, O, Al, and Tinat targets

Author

Ch. Finck, J. Colin, D. Cussol, Y. Karakaya, M. Labalme, Marc Rousseau, S. Salvador, M. Vanstalle, and C. Divay

Subjects
Physics, Systematic error, Scattering cross-section, Nuclear reaction, Carbon therapy, Quantitative Biology::Tissues and Organs, Radiation field, 01 natural sciences, 030218 nuclear medicine & medical imaging, Nuclear physics, Hadron therapy, 03 medical and health sciences, 0302 clinical medicine, Fragmentation (mass spectrometry), 0103 physical sciences, Atomic physics, Nuclear Experiment, 010306 general physics, Nucleon
Abstract

During a carbon therapy treatment, the beam undergoes inelastic nuclear reactions leading to the production of secondary fragments. These nuclear interactions tend to delocate a part of the dose into healthy tissues and create a mixed radiation field. In order to accurately estimate the dose deposited into the tissues, the production rate of these fragments all along the beam path have to be taken into account. But the double differential carbon fragmentation cross sections are not well known in the energy range needed for a treatment (up to 400 MeV/nucleon). Therefore, a series of experiments aiming to measure the double differential fragmentation cross sections of carbon on thin targets of medical interest has been started by our collaboration. In March 2015 we performed an experiment to study the fragmentation of a 50 MeV/nucleon C12 beam on thin targets at GANIL. During this experiment, energy and angular cross-section distributions on H, C, O, Al, and Tinat have been measured. The experimental set-up will be detailed as well as the systematic error study and all the experimental results will be presented.

Published
2017

3. Differential cross-sections measurements for hadrontherapy: 50 MeV/A $^{12}$C reactions on H, C, O, Al and $^{nat}$Ti targets

Author

M. Vanstalle, M. Labalme, C. Divay, J. Colin, Marc Rousseau, D. Cussol, Y. Karakaya, Ch. Finck, S. Salvador, Laboratoire de physique corpusculaire de Caen (LPCC), Université de Caen Normandie (UNICAEN), Normandie Université (NU)-Normandie Université (NU)-École Nationale Supérieure d'Ingénieurs de Caen (ENSICAEN), Normandie Université (NU)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3), Institut Pluridisciplinaire Hubert Curien (IPHC), Université de Strasbourg (UNISTRA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Laboratoire de physique corpusculaire de Caen ( LPCC ), Université de Caen Normandie ( UNICAEN ), Normandie Université ( NU ) -Normandie Université ( NU ) -Ecole Nationale Supérieure d'Ingénieurs de Caen ( ENSICAEN ), Normandie Université ( NU ) -Institut National de Physique Nucléaire et de Physique des Particules du CNRS ( IN2P3 ) -Centre National de la Recherche Scientifique ( CNRS ), Institut Pluridisciplinaire Hubert Curien ( IPHC ), Université de Strasbourg ( UNISTRA ) -Centre National de la Recherche Scientifique ( CNRS ), Normandie Université (NU)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), and Université de Strasbourg (UNISTRA)-Centre National de la Recherche Scientifique (CNRS)

Subjects
Physics, 010308 nuclear & particles physics, QC1-999, Experimental data, [PHYS.NEXP]Physics [physics]/Nuclear Experiment [nucl-ex], Channel models, 01 natural sciences, Nuclear physics, Nat, Treatment plan, 0103 physical sciences, [ PHYS.NEXP ] Physics [physics]/Nuclear Experiment [nucl-ex], 010306 general physics, Nucleon
Abstract

International audience; In order to keep the benefits of a carbon treatment, the dose and biological effects induced by secondary fragments must be taken into account when simulating the treatment plan. These Monte-Carlo simulations codes are done using nuclear models that are constrained by experimental data. It is hence necessary to have precise measurements of the production rates of these fragments all along the beam path and for its whole energy range. In this context, a series of experiments aiming to measure the double differential fragmentation cross-sections of carbon on thin targets of medical interest has been started by our collaboration. In March 2015, an experiment was performed with a 50 MeV/nucleon 12C beam at GANIL. During this experiment, energy and angular differential cross-section distributions on H, C, O, Al and natTi have been measured. In the following, the experimental set-up and analysis process are briefly described and some experimental results are presented. Comparisons between several exit channel models from Phits and Geant4 show great discrepancies with the experimental data. Finally, the homemade Sliipie model is briefly presented and preliminary results are compared to the data with a promising outcome.

Published
2016

4. Differential cross sections measurements for hadrontherapy: 50 MeV/n $^{12}$C reactions on H, C, Al, O and natTi targets

Author

M. Labalme, D. Cussol, S. Salvador, C. Divay, C. Finck, Y. Karakaya, M. Rousseau, M. Vanstalle, Laboratoire de physique corpusculaire de Caen ( LPCC ), Université de Caen Normandie ( UNICAEN ), Normandie Université ( NU ) -Normandie Université ( NU ) -Ecole Nationale Supérieure d'Ingénieurs de Caen ( ENSICAEN ), Normandie Université ( NU ) -Institut National de Physique Nucléaire et de Physique des Particules du CNRS ( IN2P3 ) -Centre National de la Recherche Scientifique ( CNRS ), Guesnon, Sandrine, Laboratoire de physique corpusculaire de Caen (LPCC), Université de Caen Normandie (UNICAEN), Normandie Université (NU)-Normandie Université (NU)-École Nationale Supérieure d'Ingénieurs de Caen (ENSICAEN), and Normandie Université (NU)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)

Subjects
Physics, [PHYS.NEXP] Physics [physics]/Nuclear Experiment [nucl-ex], Analytical chemistry, Hematology, [PHYS.NEXP]Physics [physics]/Nuclear Experiment [nucl-ex], 030218 nuclear medicine & medical imaging, 3. Good health, 03 medical and health sciences, 0302 clinical medicine, Oncology, Radiology Nuclear Medicine and imaging, 030220 oncology & carcinogenesis, C/AL, Radiology, Nuclear Medicine and imaging, [ PHYS.NEXP ] Physics [physics]/Nuclear Experiment [nucl-ex], computer, Differential (mathematics), ComputingMilieux_MISCELLANEOUS, computer.programming_language
Abstract

International audience

Published
2016

5. Timing Performances of a Time-of-Flight Detection System for Fragmentation Cross Section Measurements in Carbon Therapy

Author

J. Colin, D. Cussol, S. Salvador, J.M. Fontbonne, M. Labalme, C. Divay, Guesnon, Sandrine, Laboratoire de physique corpusculaire de Caen (LPCC), Université de Caen Normandie (UNICAEN), Normandie Université (NU)-Normandie Université (NU)-École Nationale Supérieure d'Ingénieurs de Caen (ENSICAEN), and Normandie Université (NU)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)

Subjects
Materials science, Chemical substance, [PHYS.PHYS.PHYS-MED-PH] Physics [physics]/Physics [physics]/Medical Physics [physics.med-ph], 010308 nuclear & particles physics, [PHYS.NEXP] Physics [physics]/Nuclear Experiment [nucl-ex], Quantitative Biology::Tissues and Organs, Physics::Medical Physics, Detector, Bragg peak, [PHYS.NEXP]Physics [physics]/Nuclear Experiment [nucl-ex], 01 natural sciences, Ion, Computational physics, Time of flight, 0103 physical sciences, Relative biological effectiveness, [PHYS.PHYS.PHYS-MED-PH]Physics [physics]/Physics [physics]/Medical Physics [physics.med-ph], Atomic physics, Nuclear Experiment, 010306 general physics, Proton therapy, Beam (structure), ComputingMilieux_MISCELLANEOUS
Abstract

Carbon ions therapy is being considered to replace proton therapy in the treatment of certain cancerous diseases due to a better ballistic and a higher relative biological effectiveness (RBE). However, nuclear interactions between beam particles and nuclei in the tissues reduce the primary beam intensity at the Bragg peak and create a mixed radiation field through lighter and faster fragments.

Published
2016

6. The Billotron: a way to experimentally apprehend the subatomic world

Author

D. Cussol, Julien Gibelin, Ph. Desrues, Y. Lemière, A. Chapon, D. Durand, J. Perronnel, H. Franck de Préaumont, O. Lopez, J.C. Steckmeyer, Laboratoire de physique corpusculaire de Caen (LPCC), Université de Caen Normandie (UNICAEN), Normandie Université (NU)-Normandie Université (NU)-École Nationale Supérieure d'Ingénieurs de Caen (ENSICAEN), Normandie Université (NU)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), and Normandie Université (NU)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)

Subjects
Physics, Science instruction, Structure (category theory), General Physics and Astronomy, [PHYS.NEXP]Physics [physics]/Nuclear Experiment [nucl-ex], 01 natural sciences, Engineering physics, 010305 fluids & plasmas, Education, Theoretical physics, Physics::Popular Physics, 0103 physical sciences, Subatomic particle, 010306 general physics
Abstract

International audience; The Billotron is a device designed and built by the LPC Caen to illustrate the methods with which physicists are able to study the basic structure of matter, in particular the nucleus of the atom.

Published
2015

7. The Billotron: a way to experimentally apprehend the subatomic world.

Author

A Chapon, J Gibelin, O Lopez, D Cussol, D Durand, Ph Desrues, H Franck de Préaumont, Y Lemière, J Perronnel, and J C Steckmeyer

Subjects
PARTICLES (Nuclear physics), RUTHERFORD scattering, ALPHA rays
Abstract

The Billotron is a device designed and built by the LPC Caen to illustrate the methods with which physicists are able to study the basic structure of matter, in particular the nucleus of the atom. [ABSTRACT FROM AUTHOR]

Published
2015
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