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Your search keyword '"Corrigan, Kelly A."' showing total 38 results
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38 results on '"Corrigan, Kelly A."'

2. Supplementary Data (for publication) from Polyamine Antagonist Therapies Inhibit Neuroblastoma Initiation and Progression

Author

Evageliou, Nicholas F., primary, Haber, Michelle, primary, Vu, Annette, primary, Laetsch, Theodore W., primary, Murray, Jayne, primary, Gamble, Laura D., primary, Cheng, Ngan Ching, primary, Liu, Kangning, primary, Reese, Megan, primary, Corrigan, Kelly A., primary, Ziegler, David S., primary, Webber, Hannah, primary, Hayes, Candice S., primary, Pawel, Bruce, primary, Marshall, Glenn M., primary, Zhao, Huaqing, primary, Gilmour, Susan K., primary, Norris, Murray D., primary, and Hogarty, Michael D., primary

Published
2023
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3. Please Pass the Forgiveness

Author

Corrigan, Kelly

Subjects
Forgiveness -- Religious aspects -- Personal narratives, General interest, News, opinion and commentary
Abstract

Here's a short list of things to keep handy during the holidays: throat lozenges, Scotch tape, a Dustbuster, blankets and plenty of extra forgiveness. Surely my family's Thanksgiving won't be [...]

Published
2021

4. How to Let Go of Your Irreplaceable, Unstoppable Daughter

Author

Corrigan, Kelly

Subjects
General interest
Abstract

Byline: Kelly Corrigan My 18-year-old daughter appears in the kitchen in a Ruth Bader Ginsburg sweatshirt, makes a mug of Rice Krispies treats in the microwave and shows me a [...]

Published
2021

5. My Daughter Is Not Mine to Own

Author

Corrigan, Kelly

Subjects
Parent and child -- Psychological aspects -- Personal narratives -- Social aspects, General interest, News, opinion and commentary
Abstract

My 18-year-old daughter appears in the kitchen in a Ruth Bader Ginsburg sweatshirt, makes a mug of Rice Krispies treats in the microwave and shows me a photo on her [...]

Published
2021

6. Spatial, transcriptomic, and epigenomic analyses link dorsal horn neurons to chronic pain genetic predisposition

Author

Arokiaraj, Cynthia M., Leone, Michael J., Kleyman, Michael, Chamessian, Alexander, Noh, Myung-Chul, Phan, BaDoi N., Lopes, Bettega C., Corrigan, Kelly A., Cherupally, Vijay Kiran, Yeramosu, Deepika, Franusich, Michael E., Podder, Riya, Lele, Sumitra, Shiers, Stephanie, Kang, Byungsoo, Kennedy, Meaghan M., Chen, Viola, Chen, Ziheng, Mathys, Hansruedi, Dum, Richard P., Lewis, David A., Qadri, Yawar, Price, Theodore J., Pfenning, Andreas R., and Seal, Rebecca P.

Abstract

Key mechanisms underlying chronic pain occur within the dorsal horn. Genome-wide association studies (GWASs) have identified genetic variants predisposed to chronic pain. However, most of these variants lie within regulatory non-coding regions that have not been linked to spinal cord biology. Here, we take a multi-species approach to determine whether chronic pain variants impact the regulatory genomics of dorsal horn neurons. First, we generate a large rhesus macaque single-nucleus RNA sequencing (snRNA-seq) atlas and integrate it with available human and mouse datasets to produce a single unified, species-conserved atlas of neuron subtypes. Cellular-resolution spatial transcriptomics in mouse shows the precise laminar location of these neuron subtypes, consistent with our analysis of neuron-subtype-selective markers in macaque. Using this cross-species framework, we generate a mouse single-nucleus open chromatin atlas of regulatory elements that shows strong and selective relationships between the neuron-subtype-specific chromatin regions and variants from major chronic pain GWASs.

Published
2024
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7. Mechanical Allodynia Circuitry in the Dorsal Horn Is Defined by the Nature of the Injury

Author

Peirs, Cedric, primary, Williams, Sean-Paul G., additional, Zhao, Xinyi, additional, Arokiaraj, Cynthia M., additional, Ferreira, David W., additional, Noh, Myung-chul, additional, Smith, Kelly M., additional, Halder, Priyabrata, additional, Corrigan, Kelly A., additional, Gedeon, Jeremy Y., additional, Lee, Suh Jin, additional, Gatto, Graziana, additional, Chi, David, additional, Ross, Sarah E., additional, Goulding, Martyn, additional, and Seal, Rebecca P., additional

Published
2021
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8. Advice to My College Freshman

Author

Corrigan, Kelly

Subjects
General interest
Abstract

Byline: Kelly Corrigan Don't take other people's Adderall. Granola bars have a lot of sugar. The stamp goes in the upper right-hand corner of the envelope. Any parent with an [...]

Published
2019

10. It's like this

Author

Corrigan, Kelly

Subjects
Environmental issues
Abstract

'IT'S LIKE THIS.' That's what Will liked to say. Will, the meditation guy from my husband Edward's office. Will, who had interesting answers to hard questions and didn't wear shoes. [...]

Published
2018

11. Outer mitochondrial membrane shape engages BAX α9 to initiate mitochondrial outer membrane permeabilization and apoptosis

Author

Renault, Thibaud T., Floros, Konstantinos V., Elkholi, Rana, Corrigan, Kelly-Ann, Kushnareva, Yulia, Wieder, Shira Y., Lindtner, Claudia, Serasinghe, Madhavika N., Asciolla, James J., Buettner, Christoph, Newmeyer, Donald D., and Chipuk, Jerry E.

Subjects
Membrane Potential, Mitochondrial, Bcl-2-Like Protein 11, Membrane Proteins, Apoptosis, Mitochondria, Liver, Organelle Shape, Mitochondrial Dynamics, Article, Permeability, GTP Phosphohydrolases, Mice, bcl-2 Homologous Antagonist-Killer Protein, Gene Expression Regulation, Proto-Oncogene Proteins, Mitochondrial Membranes, Animals, Apoptosis Regulatory Proteins, Unilamellar Liposomes, Signal Transduction, bcl-2-Associated X Protein
Abstract

Pro-apoptotic BCL-2 proteins converge upon the outer mitochondrial membrane (OMM) to promote mitochondrial outer membrane permeabilization (MOMP) and apoptosis. Here we investigated the mechanistic relationship between mitochondrial shape and MOMP, and provide evidence that BAX requires a distinct mitochondrial size to induce MOMP. We utilized the terminal unfolded protein response pathway to systematically define pro-apoptotic BCL-2 protein composition after stress, and then directly interrogated their requirement for a productive mitochondrial size. Complementary biochemical, cellular, in vivo, and ex vivo studies reveal that Mfn1, a GTPase involved in mitochondrial fusion, establishes a mitochondrial size that is permissive for pro-apoptotic BCL-2 family function. Cells with hyper-fragmented mitochondria, along with size-restricted OMM model systems, fail to support BAX-dependent membrane association and permeabilization due to an inability to stabilize BAXα9·membrane interactions. This work identifies an unexpected mechanistic contribution of mitochondrial size in dictating BAX activation, MOMP, and apoptosis.

Published
2014

12. Tell Me More: And other important things I'm learning to say

Author

Corrigan, Kelly

Subjects
Tell Me More (Nonfiction work) -- Corrigan, Kelly, Books -- Book reviews, Library and information science
Abstract

From the bestselling author of Glitter and Glue comes a funny, wise, and insightful exploration of the seven sentences adult life requires, with each chapter drawing on poignant and hilarious [...]

Published
2017

13. Polyamine Antagonist Therapies Inhibit Neuroblastoma Initiation and Progression

Author

Evageliou, Nicholas F., primary, Haber, Michelle, additional, Vu, Annette, additional, Laetsch, Theodore W., additional, Murray, Jayne, additional, Gamble, Laura D., additional, Cheng, Ngan Ching, additional, Liu, Kangning, additional, Reese, Megan, additional, Corrigan, Kelly A., additional, Ziegler, David S., additional, Webber, Hannah, additional, Hayes, Candice S., additional, Pawel, Bruce, additional, Marshall, Glenn M., additional, Zhao, Huaqing, additional, Gilmour, Susan K., additional, Norris, Murray D., additional, and Hogarty, Michael D., additional

Published
2016
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14. The joy of toes in the sand and eyes on a page

Author

Corrigan, Kelly

Subjects
General interest, News, opinion and commentary
Abstract

Byline: Kelly Corrigan Ah, July. Here approaches summer, for me No. 47, when work feels vaguely optional and the evening light stretches close to 9 p.m. When kids are wiped [...]

Published
2015

15. Mitochondrial Shape Governs BAX-Induced Membrane Permeabilization and Apoptosis

Author

Renault, Thibaud T., primary, Floros, Konstantinos V., additional, Elkholi, Rana, additional, Corrigan, Kelly-Ann, additional, Kushnareva, Yulia, additional, Wieder, Shira Y., additional, Lindtner, Claudia, additional, Serasinghe, Madhavika N., additional, Asciolla, James J., additional, Buettner, Christoph, additional, Newmeyer, Donald D., additional, and Chipuk, Jerry E., additional

Published
2015
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16. GLITTER AND GLUE.

Author

CORRIGAN, KELLY

Subjects
*MEMOIRS
Abstract

An excerpt from the book "Glitter and Glue: A Memoir" by Kelly Corrigan is presented.

Published
2014

17. A MATTER OF LIFE AND BREAST.

Author

Corrigan, Kelly

Abstract

A personal narrative is presented which explores the author's experience of dealing with breast cancer.

Published
2017

20. Master Your To-Do List.

Author

Corrigan, Kelly

Subjects
PSYCHOLOGY, ATTITUDE (Psychology)
Abstract

The article presents suggestions on how to clear mental clutter.

Published
2018

21. BETWEEN FRIENDS.

Author

Corrigan, Kelly

Abstract

The author writes a personal letter to her friend who has passed away, describing her day to day life activities with children and family.

Published
2017

22. Points to Ponder.

Author

CHAPPELLE, DAVE, KURLANSKY, MARK, CORRIGAN, KELLY, VANDERKAM, LAURA, and ROBERTS, JULIA

Published
2017

23. Moved by an 'Avalanche'.

Author

CORRIGAN, KELLY

Subjects
*EMPLOYMENT in foreign countries
Abstract

A personal narrative is presented which explores the author's experience of having Shawn Colvin's song "Shotgun Down the Avalanche" resonate with her while working as a waitress in New Zealand after college and meeting Colvin in 2008 in San Francisco, California.

Published
2015

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