10 results on '"Chisty, Zeshan"'
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2. Immune response kinetics to SARS-CoV-2 infection and COVID-19 vaccination among nursing home residents—Georgia, October 2020–July 2022
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Chisty, Zeshan A., primary, Li, Deana D., additional, Haile, Melia, additional, Houston, Hollis, additional, DaSilva, Juliana, additional, Overton, Rahsaan, additional, Schuh, Amy J., additional, Haynie, Jenn, additional, Clemente, Jacob, additional, Branch, Alicia G., additional, Arons, Melissa M., additional, Tsang, Clarisse A., additional, Pellegrini, Gerald J., additional, Bugrysheva, Julia, additional, Ilutsik, Justina, additional, Mohelsky, Romy, additional, Comer, Patricia, additional, Hundia, Solomon B., additional, Oh, Hyungseok, additional, Stuckey, Matthew J., additional, Bohannon, Caitlin D., additional, Rasheed, Mohammed Ata Ur, additional, Epperson, Monica, additional, Thornburg, Natalie J., additional, McDonald, L. Clifford, additional, Brown, Allison C., additional, and Kutty, Preeta K., additional
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- 2024
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3. Asymptomatic and Presymptomatic SARS-CoV-2 Infections in Residents of a Long-Term Care Skilled Nursing Facility — King County, Washington, March 2020
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Public Health – Seattle & King County, CDC COVID-19 Investigation Team, Kimball, Anne, Hatfield, Kelly M., Arons, Melissa, James, Allison, Taylor, Joanne, Spicer, Kevin, Bardossy, Ana C., Oakley, Lisa P., Tanwar, Sukarma, Chisty, Zeshan, Bell, Jeneita M., Methner, Mark, Harney, Josh, Jacobs, Jesica R., Carlson, Christina M., McLaughlin, Heather P., Stone, Nimalie, Clark, Shauna, Brostrom-Smith, Claire, Page, Libby C., Kay, Meagan, Lewis, James, Russell, Denny, Hiatt, Brian, Gant, Jessica, Duchin, Jeffrey S., Clark, Thomas A., Honein, Margaret A., Reddy, Sujan C., and Jernigan, John A.
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- 2020
4. 1941. Describing the immune response kinetics to mRNA COVID-19 vaccines among previously SARS-CoV-2–infected and –uninfected nursing home residents, a prospective longitudinal observational cohort evaluation—Georgia, October 2020 – September 2021
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Chisty, Zeshan A, primary, Haile, Melia, additional, DaSilva, Juliana, additional, Biology, M A, additional, Houston, Hollis, additional, Le, Shoshona, additional, Li, Deana, additional, Overton, Rahsaan, additional, Arons, Melissa, additional, Schuh, Amy J, additional, Tsang, Clarisse A, additional, Selenic, Dejana, additional, Clemente, Jacob, additional, Bugrysheva, Julia, additional, Branch, Alicia, additional, Thornburg, Natalie J, additional, Epperson, Monica, additional, Rasheed, Mohammed A, additional, Bohannon, Caitlin D, additional, Stuckey, Matthew J, additional, McDonald, L C, additional, Brown, Allison C, additional, and Kutty, Preeta K, additional
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- 2022
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5. Monkeypox Virus Infection Resulting from an Occupational Needlestick — Florida, 2022
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Mendoza, Rafael, primary, Petras, Julia K., additional, Jenkins, Patrick, additional, Gorensek, Margaret J., additional, Mableson, Susan, additional, Lee, Philip A., additional, Carpenter, Ann, additional, Jones, Heather, additional, de Perio, Marie A., additional, Chisty, Zeshan, additional, Brueck, Scott, additional, Rao, Agam K., additional, Salzer, Johanna S., additional, Stanek, Danielle, additional, and Blackmore, Carina, additional
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- 2022
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6. Remote Infection Control Assessments of US Nursing Homes During the COVID-19 Pandemic, April to June 2020
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Walters, Maroya Spalding, primary, Prestel, Christopher, additional, Fike, Lucy, additional, Shrivastwa, Nijika, additional, Glowicz, Janet, additional, Benowitz, Isaac, additional, Bulens, Sandra, additional, Curren, Emily, additional, Dupont, Hannah, additional, Marcenac, Perrine, additional, Mahon, Garrett, additional, Moorman, Anne, additional, Ogundimu, Abimbola, additional, Weil, Lauren M., additional, Kuhar, David, additional, Cochran, Ronda, additional, Schaefer, Melissa, additional, Slifka, Kara Jacobs, additional, Kallen, Alexander, additional, Perz, Joseph F., additional, Adeyemo, Adesubomi, additional, Bagchi, Suparna, additional, Boone, Karen, additional, Allen-Bridson, Katherine, additional, Cali, Susan, additional, Carmon, Clayton, additional, Chisty, Zeshan, additional, Duffy, Nadezhda, additional, Epstein, Lauren, additional, Goswami, Neela D., additional, Ham, D. Cal, additional, Hannan, Judy, additional, Hercules, Margaret, additional, Issa, Anindita, additional, Kolwaite ARNP, Amy, additional, Legros, Jessie, additional, Lees, Serina, additional, Lucas, Todd, additional, Matanock, Almea, additional, McClung, Nancy, additional, Moro, Pedro, additional, Nanduri, Srinivas, additional, Shugart, Alicia, additional, Sipe, Theresa, additional, Smith, Henrietta, additional, Soda, Elizabeth, additional, Somers, Tarah, additional, Umeakunne, Erica, additional, Tucker, Pattie, additional, and White, Katelyn, additional
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- 2022
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7. Asymptomatic and Presymptomatic SARS-CoV-2 Infections in Residents of a Long-Term Care Skilled Nursing Facility — King County, Washington, March 2020
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Kimball, Anne, Hatfield, Kelly M., Arons, Melissa, James, Allison, Taylor, Joanne, Spicer, Kevin, Bardossy, Ana C., Oakley, Lisa P., Tanwar, Sukarma, Chisty, Zeshan, Bell, Jeneita M., Methner, Mark, Harney, Josh, Jacobs, Jesica R., Carlson, Christina M., McLaughlin, Heather P., Stone, Nimalie, Clark, Shauna, Brostrom-Smith, Claire, Page, Libby C., Kay, Meagan, Lewis, James, Russell, Denny, Hiatt, Brian, Gant, Jessica, Duchin, Jeffrey S., Clark, Thomas A., Honein, Margaret A., Reddy, Sujan C., Jernigan, John A., Baer, Atar, Barnard, Leslie M., Benoliel, Eileen, Fagalde, Meaghan S., Ferro, Jessica, Smith, Hal Garcia, Gonzales, Elysia, Hatley, Noel, Hatt, Grace, Hope, Michaela, Huntington-Frazier, Melinda, Kawakami, Vance, Lenahan, Jennifer L., Lukoff, Margaret D., Maier, Emily B., McKeirnan, Shelly, Montgomery, Patricia, Morgan, Jennifer L., Mummert, Laura A., Pogosjans, Sargis, Riedo, Francis X., Schwarcz, Leilani, Smith, Daniel, Stearns, Steve, Sykes, Kaitlyn J., Whitney, Holly, Ali, Hammad, Banks, Michelle, Balajee, Arun, Chow, Eric J., Cooper, Barbara, Currie, Dustin W., Dyal, Jonathan, Healy, Jessica, Hughes, Michael, McMichael, Temet M., Nolen, Leisha, Olson, Christine, Rao, Agam K., Schmit, Kristine, Schwartz, Noah G., Tobolowsky, Farrell, Zacks, Rachael, and Zane, Suzanne
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Male ,Washington ,medicine.medical_specialty ,Health (social science) ,Epidemiology ,Health, Toxicology and Mutagenesis ,Pneumonia, Viral ,01 natural sciences ,Asymptomatic ,Disease Outbreaks ,Betacoronavirus ,03 medical and health sciences ,COVID-19 Testing ,0302 clinical medicine ,Health Information Management ,Pandemic ,medicine ,Humans ,Infection control ,Full Report ,030212 general & internal medicine ,0101 mathematics ,Pandemics ,Personal protective equipment ,Aged ,Skilled Nursing Facilities ,Asymptomatic Diseases ,Aged, 80 and over ,Clinical Laboratory Techniques ,SARS-CoV-2 ,business.industry ,010102 general mathematics ,COVID-19 ,Outbreak ,General Medicine ,medicine.disease ,Long-Term Care ,Long-term care ,Pneumonia ,Emergency medicine ,Female ,medicine.symptom ,Coronavirus Infections ,business - Abstract
Older adults are susceptible to severe coronavirus disease 2019 (COVID-19) outcomes as a consequence of their age and, in some cases, underlying health conditions (1). A COVID-19 outbreak in a long-term care skilled nursing facility (SNF) in King County, Washington that was first identified on February 28, 2020, highlighted the potential for rapid spread among residents of these types of facilities (2). On March 1, a health care provider at a second long-term care skilled nursing facility (facility A) in King County, Washington, had a positive test result for SARS-CoV-2, the novel coronavirus that causes COVID-19, after working while symptomatic on February 26 and 28. By March 6, seven residents of this second facility were symptomatic and had positive test results for SARS-CoV-2. On March 13, CDC performed symptom assessments and SARS-CoV-2 testing for 76 (93%) of the 82 facility A residents to evaluate the utility of symptom screening for identification of COVID-19 in SNF residents. Residents were categorized as asymptomatic or symptomatic at the time of testing, based on the absence or presence of fever, cough, shortness of breath, or other symptoms on the day of testing or during the preceding 14 days. Among 23 (30%) residents with positive test results, 10 (43%) had symptoms on the date of testing, and 13 (57%) were asymptomatic. Seven days after testing, 10 of these 13 previously asymptomatic residents had developed symptoms and were recategorized as presymptomatic at the time of testing. The reverse transcription-polymerase chain reaction (RT-PCR) testing cycle threshold (Ct) values indicated large quantities of viral RNA in asymptomatic, presymptomatic, and symptomatic residents, suggesting the potential for transmission regardless of symptoms. Symptom-based screening in SNFs could fail to identify approximately half of residents with COVID-19. Long-term care facilities should take proactive steps to prevent introduction of SARS-CoV-2 (3). Once a confirmed case is identified in an SNF, all residents should be placed on isolation precautions if possible (3), with considerations for extended use or reuse of personal protective equipment (PPE) as needed (4).
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- 2020
8. COVID-19 in a Long-Term Care Facility — King County, Washington, February 27–March 9, 2020
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McMichael, Temet M., Clark, Shauna, Pogosjans, Sargis, Kay, Meagan, Lewis, James, Baer, Atar, Kawakami, Vance, Lukoff, Margaret D., Ferro, Jessica, Brostrom-Smith, Claire, Riedo, Francis X., Russell, Denny, Hiatt, Brian, Montgomery, Patricia, Rao, Agam K., Currie, Dustin W., Chow, Eric J., Tobolowsky, Farrell, Bardossy, Ana C., Oakley, Lisa P., Jacobs, Jesica R., Schwartz, Noah G., Stone, Nimalie, Reddy, Sujan C., Jernigan, John A., Honein, Margaret A., Clark, Thomas A., Duchin, Jeffrey S., Fagalde, Meaghan S., Lenahan, Jennifer L., Maier, Emily B., Sykes, Kaitlyn J., Hatt, Grace, Whitney, Holly, Huntington-Frazier, Melinda, Gonzales, Elysia, Mummert, Laura A., Smith, Hal Garcia, Stearns, Steve, Benoliel, Eileen, McKeirnan, Shelly, Morgan, Jennifer L., Smith, Daniel, Hope, Michaela, Hatley, Noel, Barnard, Leslie M., Schwarcz, Leilani, Yarid, Nicole, Yim, Eric, Kreider, Sandra, Barr, Dawn, Wilde, Nancy, Dorman, Courtney, Lam, Airin, Harris, Jeanette, Bruce, Hollianne, Spitters, Christopher, District, Snohomish Health, Zacks, Rachael, Dyal, Jonathan, Hughes, Michael, Carlson, Christina, Cooper, Barbara, Banks, Michelle, McLaughlin, Heather, Balajee, Arun, Olson, Christine, Zane, Suzanne, Ali, Hammad, Healy, Jessica, Schmit, Kristine, Spicer, Kevin, Chisty, Zeshan, Tanwar, Sukarma, Taylor, Joanne, Nolen, Leisha, Bell, Jeneita, Hatfield, Kelly, Arons, Melissa, Kimball, Anne, James, Allison, Methner, Mark, and Harney, Joshua
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Adult ,Male ,Washington ,Health (social science) ,Coronavirus disease 2019 (COVID-19) ,Epidemiology ,Health, Toxicology and Mutagenesis ,Pneumonia, Viral ,MEDLINE ,Severe disease ,Disease ,01 natural sciences ,Residential Facilities ,Disease Outbreaks ,03 medical and health sciences ,Young Adult ,0302 clinical medicine ,Fatal Outcome ,Health Information Management ,Risk Factors ,Infection control ,Medicine ,Humans ,030212 general & internal medicine ,Full Report ,0101 mathematics ,Aged ,Skilled Nursing Facilities ,Aged, 80 and over ,Infection Control ,business.industry ,010102 general mathematics ,COVID-19 ,General Medicine ,Health care workforce ,Middle Aged ,medicine.disease ,Long-Term Care ,Long-term care ,Chronic Disease ,Female ,Medical emergency ,Skilled Nursing Facility ,business ,Coronavirus Infections - Abstract
On February 28, 2020, a case of coronavirus disease (COVID-19) was identified in a woman resident of a long-term care skilled nursing facility (facility A) in King County, Washington.* Epidemiologic investigation of facility A identified 129 cases of COVID-19 associated with facility A, including 81 of the residents, 34 staff members, and 14 visitors; 23 persons died. Limitations in effective infection control and prevention and staff members working in multiple facilities contributed to intra- and interfacility spread. COVID-19 can spread rapidly in long-term residential care facilities, and persons with chronic underlying medical conditions are at greater risk for COVID-19-associated severe disease and death. Long-term care facilities should take proactive steps to protect the health of residents and preserve the health care workforce by identifying and excluding potentially infected staff members and visitors, ensuring early recognition of potentially infected patients, and implementing appropriate infection control measures.
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- 2020
9. Presymptomatic SARS-CoV-2 Infections and Transmission in a Skilled Nursing Facility
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Arons, Melissa M., primary, Hatfield, Kelly M., additional, Reddy, Sujan C., additional, Kimball, Anne, additional, James, Allison, additional, Jacobs, Jesica R., additional, Taylor, Joanne, additional, Spicer, Kevin, additional, Bardossy, Ana C., additional, Oakley, Lisa P., additional, Tanwar, Sukarma, additional, Dyal, Jonathan W., additional, Harney, Josh, additional, Chisty, Zeshan, additional, Bell, Jeneita M., additional, Methner, Mark, additional, Paul, Prabasaj, additional, Carlson, Christina M., additional, McLaughlin, Heather P., additional, Thornburg, Natalie, additional, Tong, Suxiang, additional, Tamin, Azaibi, additional, Tao, Ying, additional, Uehara, Anna, additional, Harcourt, Jennifer, additional, Clark, Shauna, additional, Brostrom-Smith, Claire, additional, Page, Libby C., additional, Kay, Meagan, additional, Lewis, James, additional, Montgomery, Patty, additional, Stone, Nimalie D., additional, Clark, Thomas A., additional, Honein, Margaret A., additional, Duchin, Jeffrey S., additional, and Jernigan, John A., additional
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- 2020
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10. Presymptomatic SARS-CoV-2 Infections and Transmission in a Skilled Nursing Facility.
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Nowbar, Alex, Arons, Melissa M, Hatfield, Kelly M, Reddy, Sujan C, Kimball, Anne, James, Allison, Jacobs, Jesica R, Taylor, Joanne, Spicer, Kevin, Bardossy, Ana C, Oakley, Lisa P, Tanwar, Sukarma, Dyal, Jonathan W, Harney, Josh, Chisty, Zeshan, Bell, Jeneita M, Methner, Mark, Paul, Prabasaj, Carlson, Christina M, and McLaughlin, Heather P
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HEALTH ,HEALTH facility administration ,IMMUNOSUPPRESSION ,KIDNEY transplantation ,MEDICAL ethics ,NURSING care facilities ,PRIVACY ,MEDICAL triage ,INFORMATION resources ,COVID-19 - Abstract
Background: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection can spread rapidly within skilled nursing facilities. After identification of a case of Covid-19 in a skilled nursing facility, we assessed transmission and evaluated the adequacy of symptom-based screening to identify infections in residents.Methods: We conducted two serial point-prevalence surveys, 1 week apart, in which assenting residents of the facility underwent nasopharyngeal and oropharyngeal testing for SARS-CoV-2, including real-time reverse-transcriptase polymerase chain reaction (rRT-PCR), viral culture, and sequencing. Symptoms that had been present during the preceding 14 days were recorded. Asymptomatic residents who tested positive were reassessed 7 days later. Residents with SARS-CoV-2 infection were categorized as symptomatic with typical symptoms (fever, cough, or shortness of breath), symptomatic with only atypical symptoms, presymptomatic, or asymptomatic.Results: Twenty-three days after the first positive test result in a resident at this skilled nursing facility, 57 of 89 residents (64%) tested positive for SARS-CoV-2. Among 76 residents who participated in point-prevalence surveys, 48 (63%) tested positive. Of these 48 residents, 27 (56%) were asymptomatic at the time of testing; 24 subsequently developed symptoms (median time to onset, 4 days). Samples from these 24 presymptomatic residents had a median rRT-PCR cycle threshold value of 23.1, and viable virus was recovered from 17 residents. As of April 3, of the 57 residents with SARS-CoV-2 infection, 11 had been hospitalized (3 in the intensive care unit) and 15 had died (mortality, 26%). Of the 34 residents whose specimens were sequenced, 27 (79%) had sequences that fit into two clusters with a difference of one nucleotide.Conclusions: Rapid and widespread transmission of SARS-CoV-2 was demonstrated in this skilled nursing facility. More than half of residents with positive test results were asymptomatic at the time of testing and most likely contributed to transmission. Infection-control strategies focused solely on symptomatic residents were not sufficient to prevent transmission after SARS-CoV-2 introduction into this facility. [ABSTRACT FROM AUTHOR]- Published
- 2020
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