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23 results on '"Chen, Rong-Long"'

2. Characteristics and outcomes of second cancers in patients with childhood cancer: A report from the Taiwan Pediatric Oncology Group

Author

Ho, Wan-Ling, Hung, Giun-Yi, Yen, Hsiu-Ju, Yang, Yung-Li, Chang, Hsiu-Hao, Lu, Meng-Yao, Lin, Kai-Hsin, Chen, Jiann-Shiuh, Cheng, Chao-Neng, Hung, Iou-Jih, Yang, Chao-Ping, Chen, Shih-Hsiang, Liu, Hsi-Che, Yeh, Ting-Chi, Hou, Jen-Yin, Hsiao, Chih-Cheng, Sheen, Jiunn-Ming, Chang, Tai-Tsung, Wong, Tai-Tong, Miser, James S., Liu, Yen-Lin, Chen, Rong-Long, Chen, Bow-Wen, Peng, Ching-Tien, Chang, Te-Kau, Wu, Kang-Hsi, Chang, Yu-Hsiang, Wang, Jinn-Li, Wang, Shih-Chung, Lin, Ming-Tsan, Hu, Fu-Chang, Jou, Shiann-Tarng, and Lin, Dong-Tsamn

Published
2022
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3. Treatment outcomes of pediatric acute myeloid leukemia: a retrospective analysis from 1996 to 2019 in Taiwan

Author

Yang, Yung-Li, Jaing, Tang-Her, Chen, Shih-Hsiang, Liu, Hsi-Che, Hung, Iou-Jih, Lin, Dong-Tsamn, Yang, Chao-Ping, Peng, Ching-Tien, Lin, Kai-Hsin, Hsiao, Chih-Cheng, Jou, Shiann-Tarng, Chen, Jiann-Shiuh, Lin, Ming-Tsan, Wang, Shih-Chung, Chang, Te-Kau, Huang, Fang-Liang, Cheng, Chao-Neng, Wu, Kang-Hsi, Sheen, Jiunn-Ming, Chen, Shu-Huey, Lu, Meng-Yao, Hung, Giun-Yi, Yen, Hsiu-Ju, Hsieh, Yuh-Lin, Wang, Jinn-Li, Chang, Yu-Hsiang, Chang, Hsiu-Hao, Yeh, Ting-Chi, Weng, Te-Fu, Hou, Jen-Yin, Chen, Bow-Wen, Chen, Rong-Long, Wang, Lin-Yen, Ho, Wan-Ling, Chen, Yu-Chieh, Cheng, Shin-Nan, Chao, Yu-Hua, Yang, Shang-Hsien, Huang, Ting-Huan, Chou, Shu-Wei, Lin, Chien-Yu, Chen, Hsuan-Yu, Chao, Yu-Mei Y., Liang, Der-Cherng, and Chang, Tai-Tsung

Published
2021
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5. Anti-Thymocyte Globulin (ATG)-Free Nonmyeloablative Haploidentical PBSCT Plus Post-Transplantation Cyclophosphamide Is a Safe and Efficient Treatment Approach for Pediatric Acquired Aplastic Anemia

Author

Chen, Rong-Long, primary, Ip, Peng Peng, additional, Shaw, Jy-juinn, additional, Wang, Yun-Hsin, additional, Fan, Li-Hua, additional, Shen, Yi-Ling, additional, Joseph, Nithila A., additional, Chen, Tsen-Erh, additional, and Chen, Liuh-Yow, additional

Published
2022
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7. Treatment for childhood acute lymphoblastic leukemia in Taiwan: Taiwan Pediatric Oncology Group ALL‐2002 study emphasizing optimal reinduction therapy and central nervous system preventive therapy without cranial radiation

Author

Li, Meng‐Ju, Liu, Hsi‐Che, Yen, Hsiu‐Ju, Jaing, Tang‐Her, Lin, Dong‐Tsamn, Yang, Chao‐Ping, Lin, Kai‐Hsin, Hung, Iou‐Jih, Jou, Shiann‐Tarng, Lu, Meng‐Yao, Hsiao, Chih‐Cheng, Peng, Ching‐Tien, Chang, Tai‐Tsung, Wang, Shih‐Chung, Lin, Ming‐Tsan, Chen, Jiann‐Shiuh, Chang, Te‐Kau, Hung, Giun‐Yi, Wu, Kang‐Hsi, Yang, Yung‐Li, Chang, Hsiu‐Hao, Chen, Shih‐Hsiang, Yeh, Ting‐Chi, Cheng, Chao‐Neng, Lin, Pei‐Chin, Chiou, Shyh‐Shin, Sheen, Jiunn‐Ming, Cheng, Shin‐Nan, Chen, Shu‐Huey, Chang, Yu‐Hsiang, Ho, Wan‐Ling, Chao, Yu‐Hua, Chen, Rong‐Long, Chen, Bow‐Wen, Wang, Jinn‐Li, Hsieh, Yuh‐Lin, Liao, Yu‐Mei, Yang, Shang‐Hsien, Chang, Wan‐Hui, Chao, Yu‐Mei Y., and Liang, Der‐Cherng

Published
2017
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10. Surgical treatment confers prognostic significance in pediatric malignant mediastinal germ cell tumors.

Author

Huang, Ting‐Huan, Hung, Giun‐Yi, Weng, Te‐Fu, Wang, Fu‐Mien, Lee, Chih‐Ying, Lin, Dong‐Tsamn, Chen, Bow‐Wen, Lin, Kai‐Hsin, Wu, Kang‐Hsi, Liu, Hsi‐Che, Chen, Jiann‐Shiuh, Jou, Shiann‐Tarng, Hou, Jen‐Yin, Yang, Yung‐Li, Chen, Shih‐Hsiang, Chang, Hsiu‐Hao, Chiou, Shyh‐Shin, Lin, Pei‐Chin, Chen, Rong‐Long, and Hsiao, Chih‐Cheng

Subjects
GERM cell tumors, PEDIATRIC oncology, YOLK sac, TREATMENT effectiveness, PROGNOSIS, CHORIOCARCINOMA
Abstract

Background: Primary malignant mediastinal germ cell tumors (GCTs) are rare pediatric tumors that have a poorer prognosis compared to GCTs occurring elsewhere in the body. The current study aimed to assess the prognostic factors and treatment outcomes of children with primary malignant mediastinal GCT in Taiwan. Methods: The authors retrospectively reviewed children 0–18 years old who were newly diagnosed with primary malignant mediastinal GCT between January 1, 2005 and December 31, 2019 and were registered in the Taiwan Pediatric Oncology Group patient registry. The impact of presenting characteristics, including sex, age, tumor stage, histology subtype, surgical treatment, and chemotherapy regimens of the patients were analyzed. Results: This study enrolled 52 children with malignant mediastinal GCT who had a median age of 16.0 (range, 6.0–17.9) years at diagnosis. The most common histological subtypes were mixed GCTs (n = 20) and yolk sac tumors (n = 15). Advanced disease stage and choriocarcinoma histology subtype were associated inferior outcomes. Children who received surgical treatment exhibited better outcomes compared to those who did not (5‐year overall survival, 78% vs. 7%, p <.001). After comparing patients who received first‐line cisplatin‐ and carboplatin‐based chemotherapy, no difference in treatment outcomes was observed. Multivariate analysis showed that surgical management was the only independent predictor for superior OS. Conclusions: Surgical treatment is recommended for mediastinal GCT. Cisplatin‐based chemotherapy was not superior to carboplatin‐based chemotherapy as first‐line treatment and may be avoided due to toxicity concerns. Surgical treatment is recommended for pediatric malignant mediastinal germ cell tumors. Cisplatin‐based chemotherapy was not superior to carboplatin‐based chemotherapy as first‐line treatment. [ABSTRACT FROM AUTHOR]

Published
2022
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12. Characteristics and outcomes of second cancers in patients with childhood cancer: A report from the Taiwan Pediatric Oncology Group

Author

Ho, Wan-Ling, primary, Hung, Giun-Yi, additional, Yen, Hsiu-Ju, additional, Yang, Yung-Li, additional, Chang, Hsiu-Hao, additional, Lu, Meng-Yao, additional, Lin, Kai-Hsin, additional, Chen, Jiann-Shiuh, additional, Cheng, Chao-Neng, additional, Hung, Iou-Jih, additional, Yang, Chao-Ping, additional, Chen, Shih-Hsiang, additional, Liu, Hsi-Che, additional, Yeh, Ting-Chi, additional, Hou, Jen-Yin, additional, Hsiao, Chih-Cheng, additional, Sheen, Jiunn-Ming, additional, Chang, Tai-Tsung, additional, Wong, Tai-Tong, additional, Miser, James S., additional, Liu, Yen-Lin, additional, Chen, Rong-Long, additional, Chen, Bow-Wen, additional, Peng, Ching-Tien, additional, Chang, Te-Kau, additional, Wu, Kang-Hsi, additional, Chang, Yu-Hsiang, additional, Wang, Jinn-Li, additional, Wang, Shih-Chung, additional, Lin, Ming-Tsan, additional, Hu, Fu-Chang, additional, Jou, Shiann-Tarng, additional, and Lin, Dong-Tsamn, additional

Published
2021
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13. Therapeutic drug monitoring of busulfan in patients undergoing hematopoietic cell transplantation: A pilot single-center study in taiwan

Author

Apotheek KF TDM, Apotheek Klinische Farmacie, Chen, Rong Long, Fang, Li Hua, Yang, Xin Yi, Amrani, Mohsin El, Uijtendaal, Esther Veronique, Chen, Yen Fu, Ku, Wei Chi, Apotheek KF TDM, Apotheek Klinische Farmacie, Chen, Rong Long, Fang, Li Hua, Yang, Xin Yi, Amrani, Mohsin El, Uijtendaal, Esther Veronique, Chen, Yen Fu, and Ku, Wei Chi

Published
2021

14. The Adherence to MRD Time Points Is a Significantly Prognostic Predictor in an MRD-Directed Therapy for Childhood Acute Lymphoblastic Leukemia in Taiwan

Author

Liu, Hsi-Che, primary, Yeh, Ting-Chi, additional, Jaing, Tang-Her, additional, Chen, Shih-Hsiang, additional, Hsiao, Chih-Cheng, additional, Wang, Shih-Chung, additional, Wu, Kang-Hsi, additional, Huang, Fang-Liang, additional, Chiou, Shyh-Shin, additional, Yen, Hsiu-Ju, additional, Chang, Yu-Hsiang, additional, Chen, Shu-Huey, additional, Chao, Yu-Hua, additional, Cheng, Shin-Nan, additional, Wang, Jinn-Li, additional, Chen, Rong-Long, additional, Yang, Chao-Ping, additional, Hung, Iou-Jih, additional, Hou, Jen-Yin, additional, Huang, Ting-Huan, additional, Sheen, Jiunn-Ming, additional, Chen, Yu-Chieh, additional, Peng, Ching-Tien, additional, Lin, Pei-Chin, additional, Liao, Yu-Mei, additional, Chang, Te-Kau, additional, Hung, Chien-Hui, additional, and Shih, Lee-Yung, additional

Published
2019
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17. Pediatric acute lymphoblastic leukemia with t(1;19)/TCF3-PBX1in Taiwan

Author

Yen, Hsiu-Ju, primary, Chen, Shih-Hsiang, additional, Chang, Tsung-Yen, additional, Yang, Chao-Ping, additional, Lin, Dong-Tsamn, additional, Hung, Iou-Jih, additional, Lin, Kai-Hsin, additional, Chen, Jiann-Shiuh, additional, Hsiao, Chih-Cheng, additional, Chang, Tai-Tsung, additional, Chang, Te-Kao, additional, Peng, Ching-Tien, additional, Lin, Ming-Tsan, additional, Jaing, Tang-Her, additional, Liu, Hsi-Che, additional, Jou, Shiann-Tarng, additional, Lu, Meng-Yao, additional, Cheng, Chao-Neng, additional, Sheen, Jiunn-Ming, additional, Chiou, Shyh-Shin, additional, Hung, Giun-Yi, additional, Wu, Kang-Hsi, additional, Yeh, Ting-Chi, additional, Wang, Shih-Chung, additional, Chen, Rong-Long, additional, Chang, Hsiu-Hao, additional, Yang, Yung-Li, additional, Chen, Shu-Huey, additional, Cheng, Shin-Nan, additional, Chang, Yu-Hsiang, additional, Chen, Bow-Wen, additional, Hsieh, Yuh-Lin, additional, Huang, Fang-Liang, additional, Ho, Wan-Ling, additional, Wang, Jinn-Li, additional, Chang, Chia-Yau, additional, Chao, Yu-Hua, additional, Lin, Pei-Chin, additional, Chen, Yu-Chieh, additional, Liao, Yu-Mei, additional, Lin, Tung-Huei, additional, Shih, Lee-Yung, additional, and Liang, Der-Cherng, additional

Published
2017
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18. Treatment for childhood acute lymphoblastic leukemia in Taiwan: Taiwan Pediatric Oncology Group ALL-2002 study emphasizing optimal reinduction therapy and central nervous system preventive therapy without cranial radiation

Author

Li, Meng-Ju, primary, Liu, Hsi-Che, additional, Yen, Hsiu-Ju, additional, Jaing, Tang-Her, additional, Lin, Dong-Tsamn, additional, Yang, Chao-Ping, additional, Lin, Kai-Hsin, additional, Hung, Iou-Jih, additional, Jou, Shiann-Tarng, additional, Lu, Meng-Yao, additional, Hsiao, Chih-Cheng, additional, Peng, Ching-Tien, additional, Chang, Tai-Tsung, additional, Wang, Shih-Chung, additional, Lin, Ming-Tsan, additional, Chen, Jiann-Shiuh, additional, Chang, Te-Kau, additional, Hung, Giun-Yi, additional, Wu, Kang-Hsi, additional, Yang, Yung-Li, additional, Chang, Hsiu-Hao, additional, Chen, Shih-Hsiang, additional, Yeh, Ting-Chi, additional, Cheng, Chao-Neng, additional, Lin, Pei-Chin, additional, Chiou, Shyh-Shin, additional, Sheen, Jiunn-Ming, additional, Cheng, Shin-Nan, additional, Chen, Shu-Huey, additional, Chang, Yu-Hsiang, additional, Ho, Wan-Ling, additional, Chao, Yu-Hua, additional, Chen, Rong-Long, additional, Chen, Bow-Wen, additional, Wang, Jinn-Li, additional, Hsieh, Yuh-Lin, additional, Liao, Yu-Mei, additional, Yang, Shang-Hsien, additional, Chang, Wan-Hui, additional, Chao, Yu-Mei Y., additional, and Liang, Der-Cherng, additional

Published
2016
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23. Pediatric acute lymphoblastic leukemia with t(1;19)/TCF3-PBX1 in Taiwan.

Author

Yen HJ, Chen SH, Chang TY, Yang CP, Lin DT, Hung IJ, Lin KH, Chen JS, Hsiao CC, Chang TT, Chang TK, Peng CT, Lin MT, Jaing TH, Liu HC, Jou ST, Lu MY, Cheng CN, Sheen JM, Chiou SS, Hung GY, Wu KH, Yeh TC, Wang SC, Chen RL, Chang HH, Yang YL, Chen SH, Cheng SN, Chang YH, Chen BW, Hsieh YL, Huang FL, Ho WL, Wang JL, Chang CY, Chao YH, Lin PC, Chen YC, Liao YM, Lin TH, Shih LY, and Liang DC

Subjects
Adolescent, Child, Child, Preschool, Female, Humans, Infant, Infant, Newborn, Male, Oncogene Proteins, Fusion genetics, Oncogene Proteins, Fusion metabolism, Taiwan, Chromosomes, Human, Pair 1 genetics, Chromosomes, Human, Pair 1 metabolism, Chromosomes, Human, Pair 19 genetics, Chromosomes, Human, Pair 19 metabolism, Precursor B-Cell Lymphoblastic Leukemia-Lymphoma drug therapy, Precursor B-Cell Lymphoblastic Leukemia-Lymphoma genetics, Precursor B-Cell Lymphoblastic Leukemia-Lymphoma metabolism, Translocation, Genetic
Abstract

Background: In childhood acute lymphoblastic leukemia (ALL), t(1;19)(q23;p13.3) with TCF3-PBX1 fusion is one of the most frequent translocations. Historically, it has been associated with poor prognosis. Intensive treatment, however, has improved its outcome. We determined the outcome of children with this genotype treated with contemporary intensive chemotherapy in Taiwan., Procedure: In Taiwan Pediatric Oncology Group 2002 ALL studies, genotypes were determined by cytogenetic analysis and/or reverse transcriptase polymerase chain reaction assay. Based on presenting features, immunophenotype and genotype, patients were assigned to one of the three risk groups: standard risk (SR), high risk (HR), or very high risk (VHR). The patients with t(1;19)/TCF3-PBX1 were treated in the HR arm receiving more intensive chemotherapy. The outcomes of patients with t(1;19)/TCF3-PBX1 were compared to that of patients with other subtypes of B-precursor ALL (B-ALL)., Results: Of the 1,129 patients with B-ALL, 64 (5.7%) had t(1;19)/TCF3-PBX1; 51 of whom were treated in the HR arm, but 11 were treated in the VHR and 2 in the SR arm because of physician's preference. As a group, 64 patients with t(1;19)/TCF3-PBX1 had similar 5-year event-free survival (83.3 ± 4.8%) as those with TEL-AML1 (85.2 ± 3.4%, P = 0.984) or those with hyperdiploidy >50 (84.0 ± 3.1%, P = 0.748). The cumulative risk of any (isolated plus combined) central nervous system relapse among patients with t(1;19)/TCF3-PBX1 (8.7 ± 3.8%) tended to be higher than that of patients with TEL-AML1 (5.8 ± 2.3%, P = 0.749) or those with hyperdiploidy (4.1 ± 1.8%, P = 0.135), albeit the differences did not reach statistical significance., Conclusions: With contemporary intensive chemotherapy, children with t(1;19)/TCF3-PBX1 fared as well as those with favorable genotypes (TEL-AML1 or hyperdiploidy)., (© 2017 Wiley Periodicals, Inc.)

Published
2017
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