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Your search keyword '"Canepa, Gaspar E."' showing total 18 results
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18 results on '"Canepa, Gaspar E."'

2. Multiple treatment interruptions and protecting HIV-specific CD4 T cells enable durable CD8 T cell response and viral control

Author

Jain, Anshika, primary, Canepa, Gaspar E., additional, Liou, Mei-Ling, additional, Fledderman, Emily L., additional, Chapoval, Andrei I., additional, Xiao, Lingzhi, additional, Mukherjee, Ipsita, additional, Balogun, Bushirat M., additional, Huaman-Vergara, Hellen, additional, Galvin, Jeffrey A., additional, Kumar, Princy N., additional, Bordon, José, additional, Conant, Marcus A., additional, and Boyle, Jefferey S., additional

Published
2024
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5. Multiple Treatment Interruptions and Protecting HIV-Specific CD4 T-Cells Enables Durable CTL Response and Viral Control

Author

Jain, Anshika, primary, Canepa, Gaspar E., additional, Liou, Mei-Ling, additional, Fledderman, Emily L., additional, Chapoval, Andrei I., additional, Xiao, Lingzhi, additional, Mukherjee, Ipsita, additional, Galvin, Jeffrey A., additional, Kumar, Princy N., additional, Bordon, Jose, additional, Conant, Marcus A., additional, and Boyle, Jefferey S., additional

Published
2023
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13. Integrating Scientific English into Biological Sciences PhD Programs in Developing Countries: Strategies from Trainees and Mentor

Author

Coelho, Camila H., Canepa, Gaspar E., Arora, Gunjan, and Duffy, Patrick E.

Subjects
Article Subject, ComputingMilieux_COMPUTERSANDEDUCATION
Abstract

Successful researchers in the biological sciences communicate their work to a global audience and must do so in English to be widely recognized and cited. This applies equally to scientific talks, posters, and published articles; thus, scientific English must be prioritized in nonnative English-speaking (NNES) academic institutions to prepare their trainees for successful careers. Here, we propose strategies for integrating scientific English into PhD programs operating in NNES countries. Many graduate students from NNES countries strive for an international career and encounter English as an important barrier. Based on our own experiences as NNES postdoctoral fellows at a US institution, or as a US mentor of these trainees, we contend that conventional learning processes at home institutions do not sufficiently prioritize scientific English as the medium for regular discussions of laboratory-generated data. Principal investigators, mentors, and supervisors are key in promoting English language usage as a structured component of PhD training. If these stakeholders routinely integrate English training and education within the research laboratory program, graduates will be equipped to pursue international academic careers. The ideas presented here are intended for NNES PhD students (and their mentors) who seek an international scientific career in the biological sciences.

Published
2019
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18. The heat shock protein Hsc70-3 mediates an anti-apoptotic response critical for Plasmodium evasion of Anopheles gambiae immunity.

Author

Alves E Silva TL, Canepa GE, Sweeney B, Hessab Alvarenga P, Zhao M, Vega-Rodríguez J, Molina-Cruz A, and Barillas-Mury C

Subjects
Animals, Humans, Plasmodium falciparum, Heat-Shock Proteins metabolism, Anopheles parasitology, Plasmodium, Malaria
Abstract

Importance: Malaria transmission by Anopheles gambiae mosquitoes is very effective, in part because the parasite expresses a surface protein called Pfs47 that allows it to evade the mosquito immune system. Here we investigate how this protein changes the response of mosquito midgut epithelial cells to invasion by the parasite. Pfs47 is known to interact with P47Rec, a mosquito midgut receptor. We found that Pf47Rec inhibits caspase-mediated apoptosis by interacting with the Hsc70-3. This disrupts nitration of midgut epithelial cells invaded by the parasite and the release of hemocyte-derived microvesicles, which are critical for effective activation of the mosquito complement system that eliminates the parasite., Competing Interests: The authors declare no conflict of interest.

Published
2023
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