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Your search keyword '"Camilleri-Podesta, Marie-Therese"' showing total 7 results
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7 results on '"Camilleri-Podesta, Marie-Therese"'

2. The clinical bank of BBMRI.mt

Author

Vella, Joanna, Grech, Laura, Scerri, Jeanesse, Scerri, Christian, Bezzina Wettinger, Stephanie, Camilleri, Graziella, Zammit, Esther, Grech, Godfrey, Soler, Doriette, Borg, Isabella, Camilleri Podesta, Marie Therese, Abela, Mark, Ebejer, Jean Paul, Borg, Joseph, Galdies, Ruth, Cassar, Wilhelmina, Camilleri, Alexander, Farrugia, Rosienne, Pace, Nikolai P., Said Conti, Valerie, Vella, Norbert, Saliba, Christian, Said, Edith, Ellul, Bridget, Grima, David, Felice, Alex E., and HandsOn : Biobanks 2015 -The EXPOnential Relevance of Biobanking. Clinical Biobanks for Personalized Medicine

Subjects
Biobanks -- Malta, Rare diseases -- Malta
Abstract

The Malta BioBank forms part of the new inter-faculty Centre for Molecular Medicine and BioBanking at the University of Malta and is the BBMRI-ERIC national node of Malta (BBMRI.mt) (Refer to Poster 82). The business model of the Clinical Bank is based on a collaboration between the University of Malta, the Department of Health and Mater Dei Hospital’s departments including Pathology, Paediatrics, Neurology and Oncology. The clinical catalogue holds a number of disease collections including: the Globin Bank; Parkinson’s Disease (PD); Diabetes; Multiple Sclerosis; Renal Disorders; various cancers including breast, colon, lung and gastric cancer; and a number of rare diseases., N/A

Published
2015

3. Rare disease research and the Malta biobank

Author

Vella, Joanna, Borg, Joseph, Grech, Laura, Galdies, Ruth, Scerri, Jeanesse, Cassar, Wilhelmina, Scerri, Christian, Grech, Godfrey, Soler, Doriette, Said, Edith, Borg, Isabella, Vella, Norbert, Camilleri Podesta, Marie Therese, Ellul, Bridget, Abela, Mark, Grima, David, Zammit, Esther, Pace, Nikolai P., Felice, Alex E., Said Conti, Valerie, and RD-Connect Annual Meeting

Subjects
Biobanks -- Malta, Rare diseases -- Malta
Abstract

The Malta BioBank forms part of the new inter-faculty Centre of Molecular Medicine and BioBanking at the University of Malta and is the national node of the Bio-Banking and Bio-Molecular Resources Research Infrastructure (BBMRI.mt). The clinical catalogue holds a number of rare disease collections including haemoglobinopathies, neuromuscular and neurodegenerative diseases, renal disorders and various cancers. The Department of Physiology & Biochemistry and the Department of Pathology within the Faculty of Medicine & Surgery at the University of Malta caries out various lines of research amongst which are KLF mutation analysis, familial breast cancer, mitochondrial disorders, sudden cardiac death and rare kidney disorders., N/A

Published
2015

4. Targeting the mevalonate and mammalian target of rapamycin pathways in breast cancer

Author

Petroni, Vanessa, Fenech, Anthony G., Camilleri Podesta, Marie Therese, Grech, Godfrey, and Ninth Malta Medical School Conference

Subjects
mTOR associated protein, LST8 homolog, Statins (Cardiovascular agents), Breast -- Cancer -- Treatment -- Malta, Rapamycin, Hydroxymethylglutaryl coenzyme A reductases
Abstract

Introduction: Breast cancer is the commonest cause of cancer mortality in Maltese females. The availability of eukaryotic translation initiation factor 4E (eIF4E) is reduced by mammalian target of rapamycin (mTOR) inhibitors e.g. rapamycin and metformin. Expression of 3-hydroxy-3-methylglutarylcoenzynre A reductase (HMG-CoA reductase), the mevalonate pathway rate limiting enzyme, is regulated by eIF4E. Additionally statins e.g. simvastatin, are HMG-CoA reductase inhibitors., peer-reviewed

Published
2015

5. Differential expression of breast cancer signature genes following rapamycin treatment

Author

Petroni, Vanessa, Fenech, Anthony G., Saliba, Christian, Camilleri Podesta, Marie Therese, Baldacchino, Shawn, Grech, Godfrey, and Ninth Malta Medical School Conference

Subjects
Breast -- Cancer -- Treatment, Rapamycin -- Effectiveness, MCF-7 cells, MTOR inhibitors, Aurora Kinase A
Abstract

Introduction: Breast cancer is classified into intrinsic molecular subtypes, each relating to predictive prognostic and clinical outcomes. Rapamycin inhibits the mammalian target of rapamycin (mTOR) pathway, which is often deregulated in various types of cancer. mTOR inhibitors are associated with antiproliferation and apoptosis. Aim: Investigating the differential expression of breast cancer signature genes following rapamycin treatment in various breast cancer subtypes., peer-reviewed

Published
2015

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