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1. Nodding syndrome may be an autoimmune reaction to the parasitic worm Onchocerca volvulus.

Author

Johnson, Tory P., Tyagi, Richa, Lee, Paul R., Myoung-Hwa Lee, Johnson, Kory R., Kowalak, Jeffrey, Elkahloun, Abdel, Medynets, Marie, Hategan, Alina, Kubofcik, Joseph, Sejvar, James, Ratto, Jeffrey, Bunga, Sudhir, Makumbi, Issa, Aceng, Jane R., Nutman, Thomas B., Dowell, Scott F., and Nath, Avindra

Subjects
AUTOANTIBODIES, CARCINOGENESIS, IMMUNOGLOBULINS, AUTOIMMUNITY, CENTRAL nervous system, NEUROTOXICOLOGY
Abstract

The article presents a study that investigated whether autoantibodies could be a contributing factor to the pathogenesis of nodding syndrome. Topics discussed include autoantibodies in patients with nodding syndrome, expression of leiomodin-1 antibodies in the central nervous system and neurotoxicity of leiomodin-1 antibodies.

Published
2017
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