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128 results on '"Azeka, Estela"'

4. Prevalence and clinical characteristics of oral lesions in heart transplant patients induced by sirolimus and everolimus: a systematic review and meta-analysis on a global scale

Author

Moura, Anne Evelyn Oliveira, Besseler, Mariana Oliveira, Pérez-de-Oliveira, Maria Eduarda, Normando, Ana Gabriela Costa, Neves, Itamara Lucia Itagiba, Neves, Ricardo Simões, Vargas, Pablo Agustin, Azeka, Estela, Santos-Silva, Alan Roger, and Montano, Tânia Cristina Pedroso

Published
2024
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13. Rivaroxaban compared with standard anticoagulants for the treatment of acute venous thromboembolism in children: a randomised, controlled, phase 3 trial

Author

Molinari, Angelo C., Nowak Göttl, Ulrike, Chain, Juan, Robertson, Jeremy, Thom, Katharina, Streif, Werner, Schwarz, Rudolf, Schmitt, Klaus, Grangl, Gernot, Van Damme, An, Maes, Philip, Labarque, Veerle, Petrilli, Antonio, Loggeto, Sandra, Azeka, Estela, Brandao, Leonardo, Le, Doan, Sabapathy, Christine, Giordano, Paola, Wu, Runhui, Ding, Jie, Huang, Wenyan, Mao, Jianhua, Lähteenmäki, Päivi, Amedro, Pascal, Decramer, Stephane, Bernig, Toralf, Chada, Martin, Chan, Godfrey, Kally, Krisztian, Nolan, Beatrice, Revel-Vilk, Shoshana, Tamary, Hannah, Levin, Carina, Tormene, Daniela, Abbattista, Maria, Artoni, Andrea, Ikeyama, Takanari, Inuzuka, Ryo, Yasukochi, Satoshi, Morales Soto, Michelle, Solis Labastida, Karina A, Suijker, Monique H, Bartels, Marike, Tamminga, Rienk Y, Van Ommen, C Heleen, Te Loo, D. Maroeska, Anjos, Rui, Zubarovskaya, Lyudmila, Popova, Natalia, Samochatova, Elena, Belogurova, Margarita, Svirin, Pavel, Shutova, Tatiana, Lebedev, Vladimir, Barbarash, Olga, Koh, Pei L, Mei, Joyce C, Podracka, Ludmila, Berrueco, Ruben, Fernandez, Maria F, Frisk, Tony, Grunt, Sebastian, Rischewski, Johannes, Albisetti-Pedroni, Manuela, Antmen, Ali, Tokgoz, Huseyin, Karakas, Zeynep, Chalmers, Elizabeth, Motwani, Jayashree, Williams, Michael, Grainger, John, Payne, Jeanette, Richards, Mike, Baird, Susan, Bhatnagar, Neha, Aramburo, Angela, Crary, Shelley, Wynn, Tung, Carpenter, Shannon, Hege, Kerry, Ahuja, Sanjay, Goldenberg, Neil, Woods, Gary, Godder, Kamar, Scott-Emuakpor, Ajovi, Roach, Gavin, Raffini, Leslie, Shah, Nirmish, Shah, Sanjay, Thornburg, Courtney, Zia, Ayesha, Berkow, Roger, Male, Christoph, Lensing, Anthonie W A, Palumbo, Joseph S, Kumar, Riten, Nurmeev, Ildar, Bonnet, Damien, Connor, Philip, Hooimeijer, Hélène L, Torres, Marcela, Chan, Anthony K C, Kenet, Gili, Holzhauer, Susanne, Santamaría, Amparo, Simioni, Paolo, Bhat, Rukhmi V, Yee, Donald L, Lvova, Olga, Beyer-Westendorf, Jan, Biss, Tina T, Martinelli, Ida, Saracco, Paola, Peters, Marjolein, Kállay, Krisztián, Gauger, Cynthia A, Massicotte, M Patricia, Young, Guy, Pap, Akos F, Majumder, Madhurima, Smith, William T, Heubach, Jürgen F, Berkowitz, Scott D, Thelen, Kirstin, Kubitza, Dagmar, Crowther, Mark, Prins, Martin H, and Monagle, Paul

Published
2020
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18. Successful implementation of telehealth visits in the paediatric heart failure and heart transplant population.

Author

Bansal, Neha, D'Souza, Nikita, Wisotzkey, Bethany L., Albers, Erin, Shih, Renata, Exil, Vernat, McQueen, Melissa, Hillenburg, Joseph P., Azeka, Estela, Law, Sabrina, Peng, David M., O'Connor, Matthew, Gajarski, Robert, Vanderpluym, Christina, Lorts, Angela, Barnes, Aliessa, Sojka, Melanie, Bano, Maria, Keating, Megan, and Rosenthal, David N.

Published
2024
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19. Role of HLA in cardiothoracic transplantation.

Author

Grutter, Giorgia, Bianculli, Antonio Giuseppe, Azeka, Estela, Giustiniani, Paola, Iodice, Francesca Giovanna, Amodeo, Antonio, and Andreani, Marco

Subjects
IMMUNOGLOBULINS, HEART transplant recipients, ANTIBODY formation, GRAFT rejection, HEART transplantation, LUNG transplantation, MONOCLONAL antibodies
Abstract

In current clinical practice, transplant clinicians create collaborative working relationships with histocompatibility laboratory scientists to identify the risk of long‐term graft failure, which may assist in establishing strategies for treatment and surveillance. Transplant immunology research also focuses on optimizing human leukocyte antibody tissue typing and defines the most effective test for detecting the presence of donor‐specific antibodies. Although several studies have been conducted, data on pediatric heart transplant recipients are limited. Epitope load information may be utilized to identify donors with permissible human leukocyte antibody mismatches to increase transplant success. Although current guidelines do not consider human leukocyte antibody epitope‐based matching tools, these guidelines could be useful for identifying recipients at a high risk of donor‐specific antibody production, which would be appropriate for routine donor‐specific antibody screening to initiate early interventions to prevent antibody‐mediated rejection. Human leukocyte antibody matching at the epitope level offers an effective approach for identifying acceptable mismatches in sensitized patients and provides information about epitope loads. In the future, eplet matching may be used to define the best immunosuppressive therapy protocol for cardiothoracic organ transplantation. This report provides an overview of the role of human leukocyte antibodies in heart and lung transplantation. [ABSTRACT FROM AUTHOR]

Published
2024
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20. Prevalence and clinical characteristics of oral lesions in heart transplant patients induced by Sirolimus and Everolimus: a systematic review and meta-analysis on a global scale

Author

Moura, Anne Evelyn Oliveira, primary, Besseler, Mariana Oliveira, additional, Pérez-de-Oliveira, Maria Eduarda, additional, Normando, Ana Gabriela Costa, additional, Neves, Itamara Lucia Itagiba, additional, Neves, Ricardo Simões, additional, Vargas, Pablo Agustin, additional, Azeka, Estela, additional, Santos-Silva, Alan Roger, additional, and Montano, Tânia Cristina Pedroso, additional

Published
2023
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21. Successful implementation of telehealth visits in the paediatric heart failure and heart transplant population

Author

Bansal, Neha, primary, D'Souza, Nikita, additional, Wisotzkey, Bethany L., additional, Albers, Erin, additional, Shih, Renata, additional, Exil, Vernat, additional, McQueen, Melissa, additional, Hillenburg, Joseph P., additional, Azeka, Estela, additional, Law, Sabrina, additional, Peng, David M., additional, O’Connor, Matthew, additional, Gajarski, Robert, additional, Vanderpluym, Christina, additional, Lorts, Angela, additional, Barnes, Aliessa, additional, Sojka, Melanie, additional, Bano, Maria, additional, Keating, Megan, additional, Rosenthal, David N., additional, Conway, Jennifer, additional, Schroeder, Katie, additional, and Nandi, Deipanjan, additional

Published
2023
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24. Brain tuberculoma in pediatric heart transplant recipient

Author

de Oliveira, Pedro Carpini, primary, Braz Corbi, Maria Julia de Aro, additional, Siqueira, Adailson Wagner da Silva, additional, Navajasegaran, Joshua, additional, Mesquita, Ana Sofia Silva, additional, Frassetto, Fernando Pereira, additional, Jatene, Marcelo Bisceglli, additional, Ikari, Nana Miura, additional, and Azeka, Estela, additional

Published
2023
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25. Posterior reversible encephalopathy syndrome (PRES) after pediatric heart transplantation: A multi-institutional cohort

Author

Kemna, Mariska S, primary, Shaw, Dennis W., additional, Kronmal, Richard A., additional, Ameduri, Rebecca K., additional, Azeka, Estela, additional, Bradford, Tamara T., additional, Kindel, Steven J., additional, Lin, Kimberly Y., additional, Möller, Thomas, additional, Reardon, Leigh C., additional, Schumacher, Kurt R., additional, Shih, Renata, additional, Stendahl, Gail L., additional, West, Shawn C., additional, Wisotzkey, Bethany, additional, Zangwill, Steven, additional, and Menteer, Jondavid, additional

Published
2023
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26. The Fontan immunophenotype and post‐transplant outcomes in children: A multi‐institutional study

Author

Mantell, Benjamin S., primary, Azeka, Estela, additional, Cantor, Ryan S., additional, Carlo, Waldemar F., additional, Chrisant, Maryanne, additional, Dykes, John C., additional, Hoffman, Timothy M., additional, Kirklin, James K., additional, Koehl, Devin, additional, L'Ecuyer, Thomas J., additional, McAllister, Jennie M., additional, Prada‐Ruiz, Adriana C., additional, and Richmond, Marc E., additional

Published
2023
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28. The International Society for Heart and Lung Transplantation (ISHLT) Guidelines for the Care of Heart Transplant Recipients

Author

Velleca, Angela, primary, Shullo, Michael A, additional, Dhital, Kumud, additional, Azeka, Estela, additional, Colvin, Monica, additional, DePasquale, Eugene, additional, Farrero, Marta, additional, García-Guereta, Luis, additional, Jamero, Gina, additional, Khush, Kiran, additional, Lavee, Jacob, additional, Pouch, Stephanie, additional, Patel, Jignesh, additional, Michaud, CJ, additional, Shullo, Michael, additional, Schubert, Stephan, additional, Angelini, Annalisa, additional, Carlos, Lilibeth, additional, Mirabet, Sonia, additional, Pham, Michael, additional, Urschel, Simon, additional, Kim, Kyung-Hee, additional, Miyamoto, Shelly, additional, Chih, Sharon, additional, Daly, Kevin, additional, Grossi, Paolo, additional, Jennings, Doug, additional, Kim, In-cheol, additional, Lim, Hoong Sern, additional, Miller, Tara, additional, Potena, Luciano, additional, Velleca, Angela, additional, Eisen, Howard, additional, Bellumkonda, Lavanya, additional, Danziger-Isakov, Lara, additional, Dobbels, Fabienne, additional, Harkess, Michelle, additional, Kim, Daniel, additional, Lyster, Haifa, additional, Peled, Yael, additional, and Reinhardt, Zdenka, additional

Published
2022
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29. Desmoid tumour of the chest wall in paediatric post-operatory of heart transplant

Author

Freitas Filho, Orival de, Nakahira, Evelyn Sue, Schmidt Junior, Aurelino Fernandes, Azeka, Estela, Jatene, Marcelo Biscegli, and Pego-Fernardes, Paulo Manuel

Subjects
Pediatrics, Perinatology and Child Health
Abstract

We will report a case of a desmoid tumour (DT), which developed at the surgical site of the pacemaker after a late childhood heart transplant. Patients with idiopathic dilated cardiomyopathy followed up in the paediatric cardiology service. It evolved with the dissociation of ventricular rhythm caused by severe heart failure, which led to the implantation of a cardiac resynchronization device prior to heart transplantation. The progression to end-stage heart disease culminated in a heart transplant at 12 years old. One year after the transplant, at the age of 13 years, he presented a progressively growing mass on the generator site of the resynchronization device. The initial decision was to remove the device. During the removal surgery, there was no haematoma or fluid collection. However, there was a progression of the lesion. The lesion was biopsied with the anatomopathological diagnosis of a DT. Resection surgery happened 4 months after the start of the mass growth. At that time, the tumour reached 20 cm in diameter. The lesion infiltrated the pectoralis major muscle and this muscle was resected partially en bloc with the lesion. The defect had primary closure. The patient evolved without postoperative complications and was discharged on the 14th postoperative day. The surgical specimen came with negative circumferential margins. However, the deep margin was microscopically positive. Due to deep involvement, the patient underwent adjuvant radiotherapy. Currently, the patient is under clinical follow-up and has no evidence of tumour recurrence. DT is a rare tumour, with unpredictable courses. Surgery can be considered in the progression of lesions. Treatment is justified by long survival after a heart transplant and in DT patients. DT is a differential diagnosis to be considered in progressive growth lesions.

Published
2022

31. Clinical approach to antibody‐mediated rejection from the pediatric heart transplant society

Author

Amdani, Shahnawaz, primary, Henderson, Heather, additional, Everitt, Melanie D., additional, Beasley, Gary, additional, Shih, Renata, additional, Exil, Vernat, additional, Alejos, Juan, additional, Wallis, Gonzalo, additional, Azeka, Estela, additional, Nandi, Deipanjan, additional, Profita, Elizabeth, additional, Spinner, Joseph, additional, Magnetta, Defne, additional, Martinez, Hugo, additional, Fenton, Matthew, additional, Conway, Jennifer, additional, and Urschel, Simon, additional

Published
2022
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36. CONGENITAL HEART DISEASE IN ADULTS - A NEW PROFILE INSPIRES A NEW PARADIGM

Author

Dinardi, Layara Fernanda Lipari, primary, Devido, Marcela, additional, Pereira, Thiago Vicente, additional, Romano, Gabriel Leiros, additional, Zorzanelli, Leina, additional, Thomaz, Ana Maria, additional, Tanaka, Ana Cristina, additional, Siqueira, Adailson Vagner da Silva, additional, Ikari, Nana Miura, additional, and Azeka, Estela, additional

Published
2021
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37. Desafios logísticos na alocação de corações no Brasil: uma análise dos transplantes interestaduais.

Author

Antibas Atik, Fernando, Ferreira, Gustavo F., Pêgo-Fernandes, Paulo Manoel, Azeka, Estela, Stolf, Noedir, and Salomão Pontes, Daniela

Subjects
BLOOD groups, HEART transplantation, RACE, HEART, SUPPLIERS
Abstract

Copyright of Brazilian Journal of Cardiovascular Surgery is the property of Sociedade Brasileira de Cirurgia Cardiovascular and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2024

38. A Comprehensive and Contemporary Review on Immunosuppression Therapy for Heart Transplantation

Author

Goldraich, Livia A., primary, Leitão, Santiago A. Tobar, additional, Scolari, Fernando L., additional, Marcondes-Braga, Fabiana G., additional, Bonatto, Marcely G., additional, Munyal, Dipika, additional, Harrison, Jennifer, additional, Ribeiro, Rafaela V.P., additional, Azeka, Estela, additional, Piardi, Diogo, additional, Costanzo, Maria R., additional, and Clausell, Nadine, additional

Published
2020
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41. ISHLT consensus statement on donor organ acceptability and management in pediatric heart transplantation

Author

Kirk, Richard, primary, Dipchand, Anne I., additional, Davies, Ryan R., additional, Miera, Oliver, additional, Chapman, Gretchen, additional, Conway, Jennifer, additional, Denfield, Susan, additional, Gossett, Jeffrey G., additional, Johnson, Jonathan, additional, McCulloch, Michael, additional, Schweiger, Martin, additional, Zimpfer, Daniel, additional, Ablonczy, László, additional, Adachi, Iki, additional, Albert, Dimpna, additional, Alexander, Peta, additional, Amdani, Shahnawaz, additional, Amodeo, Antonio, additional, Azeka, Estela, additional, Ballweg, Jean, additional, Beasley, Gary, additional, Böhmer, Jens, additional, Butler, Alison, additional, Camino, Manuela, additional, Castro, Javier, additional, Chen, Sharon, additional, Chrisant, Maryanne, additional, Christen, Urs, additional, Danziger-Isakov, Lara, additional, Das, Bibhuti, additional, Everitt, Melanie, additional, Feingold, Brian, additional, Fenton, Matthew, additional, Garcia-Guereta, Luis, additional, Godown, Justin, additional, Gupta, Dipankar, additional, Irving, Claire, additional, Joong, Anna, additional, Kemna, Mariska, additional, Khulbey, Sanjeev Kumar, additional, Kindel, Steven, additional, Knecht, Kenneth, additional, Lal, Ashwin K., additional, Lin, Kimberly, additional, Lord, Karen, additional, Möller, Thomas, additional, Nandi, Deipanjan, additional, Niesse, Oliver, additional, Peng, David M., additional, Pérez-Blanco, Alicia, additional, Punnoose, Ann, additional, Reinhardt, Zdenka, additional, Rosenthal, David, additional, Scales, Angie, additional, Scheel, Janet, additional, Shih, Renata, additional, Smith, Jonathan, additional, Smits, Jacqueline, additional, Thul, Josef, additional, Weintraub, Robert, additional, Zangwill, Steve, additional, and Zuckerman, Warren A., additional

Published
2020
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42. Pediatric cardiac waitlist mortality—Still too high

Author

Denfield, Susan W., primary, Azeka, Estela, additional, Das, Bibhuti, additional, Garcia‐Guereta, Luis, additional, Irving, Claire, additional, Kemna, Mariska, additional, Reinhardt, Zdenka, additional, Thul, Josef, additional, Dipchand, Anne I., additional, Kirk, Richard, additional, Davies, Ryan R., additional, and Miera, Oliver, additional

Published
2020
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43. Rivaroxaban compared with standard anticoagulants for the treatment of acute venous thromboembolism in children: a randomised, controlled, phase 3 trial

Author

Male, Christoph, primary, Lensing, Anthonie W A, additional, Palumbo, Joseph S, additional, Kumar, Riten, additional, Nurmeev, Ildar, additional, Hege, Kerry, additional, Bonnet, Damien, additional, Connor, Philip, additional, Hooimeijer, Hélène L, additional, Torres, Marcela, additional, Chan, Anthony K C, additional, Kenet, Gili, additional, Holzhauer, Susanne, additional, Santamaría, Amparo, additional, Amedro, Pascal, additional, Chalmers, Elizabeth, additional, Simioni, Paolo, additional, Bhat, Rukhmi V, additional, Yee, Donald L, additional, Lvova, Olga, additional, Beyer-Westendorf, Jan, additional, Biss, Tina T, additional, Martinelli, Ida, additional, Saracco, Paola, additional, Peters, Marjolein, additional, Kállay, Krisztián, additional, Gauger, Cynthia A, additional, Massicotte, M Patricia, additional, Young, Guy, additional, Pap, Akos F, additional, Majumder, Madhurima, additional, Smith, William T, additional, Heubach, Jürgen F, additional, Berkowitz, Scott D, additional, Thelen, Kirstin, additional, Kubitza, Dagmar, additional, Crowther, Mark, additional, Prins, Martin H, additional, Monagle, Paul, additional, Molinari, Angelo C., additional, Nowak Göttl, Ulrike, additional, Chain, Juan, additional, Robertson, Jeremy, additional, Thom, Katharina, additional, Streif, Werner, additional, Schwarz, Rudolf, additional, Schmitt, Klaus, additional, Grangl, Gernot, additional, Van Damme, An, additional, Maes, Philip, additional, Labarque, Veerle, additional, Petrilli, Antonio, additional, Loggeto, Sandra, additional, Azeka, Estela, additional, Brandao, Leonardo, additional, Le, Doan, additional, Sabapathy, Christine, additional, Giordano, Paola, additional, Wu, Runhui, additional, Ding, Jie, additional, Huang, Wenyan, additional, Mao, Jianhua, additional, Lähteenmäki, Päivi, additional, Decramer, Stephane, additional, Bernig, Toralf, additional, Chada, Martin, additional, Chan, Godfrey, additional, Kally, Krisztian, additional, Nolan, Beatrice, additional, Revel-Vilk, Shoshana, additional, Tamary, Hannah, additional, Levin, Carina, additional, Tormene, Daniela, additional, Abbattista, Maria, additional, Artoni, Andrea, additional, Ikeyama, Takanari, additional, Inuzuka, Ryo, additional, Yasukochi, Satoshi, additional, Morales Soto, Michelle, additional, Solis Labastida, Karina A, additional, Suijker, Monique H, additional, Bartels, Marike, additional, Tamminga, Rienk Y, additional, Van Ommen, C Heleen, additional, Te Loo, D. Maroeska, additional, Anjos, Rui, additional, Zubarovskaya, Lyudmila, additional, Popova, Natalia, additional, Samochatova, Elena, additional, Belogurova, Margarita, additional, Svirin, Pavel, additional, Shutova, Tatiana, additional, Lebedev, Vladimir, additional, Barbarash, Olga, additional, Koh, Pei L, additional, Mei, Joyce C, additional, Podracka, Ludmila, additional, Berrueco, Ruben, additional, Fernandez, Maria F, additional, Frisk, Tony, additional, Grunt, Sebastian, additional, Rischewski, Johannes, additional, Albisetti-Pedroni, Manuela, additional, Antmen, Ali, additional, Tokgoz, Huseyin, additional, Karakas, Zeynep, additional, Motwani, Jayashree, additional, Williams, Michael, additional, Grainger, John, additional, Payne, Jeanette, additional, Richards, Mike, additional, Baird, Susan, additional, Bhatnagar, Neha, additional, Aramburo, Angela, additional, Crary, Shelley, additional, Wynn, Tung, additional, Carpenter, Shannon, additional, Ahuja, Sanjay, additional, Goldenberg, Neil, additional, Woods, Gary, additional, Godder, Kamar, additional, Scott-Emuakpor, Ajovi, additional, Roach, Gavin, additional, Raffini, Leslie, additional, Shah, Nirmish, additional, Shah, Sanjay, additional, Thornburg, Courtney, additional, Zia, Ayesha, additional, and Berkow, Roger, additional

Published
2020
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44. Pediatric Heart Transplantation

Author

Azeka, Estela

Subjects
Medical
Abstract

Despite advances in medical management, patients submitted for heart transplantation procedures still are at risk to development of complications. This chapter will discuss some specific topics of pediatric heart transplantation, focusing on perioperative care: (i) recipient management, (ii) donor evaluation, (iii) immunosuppression, (iv) early postoperative management, (v) complications, and (vi) conclusions.

Published
2018

45. Atualização da Diretriz de Ressuscitação Cardiopulmonar e Cuidados Cardiovasculares de Emergência da Sociedade Brasileira de Cardiologia - 2019

Author

Bernoche, Claudia, primary, Timerman, Sergio, additional, Polastri, Thatiane Facholi, additional, Giannetti, Natali Schiavo, additional, Siqueira, Adailson Wagner da Silva, additional, Piscopo, Agnaldo, additional, Soeiro, Alexandre de Matos, additional, Reis, Amélia Gorete Afonso da Costa, additional, Tanaka, Ana Cristina Sayuri, additional, Thomaz, Ana Maria, additional, Quilici, Ana Paula, additional, Catarino, Andrei Hilário, additional, Ribeiro, Anna Christina de Lima, additional, Barreto, Antonio Carlos Pereira, additional, Azevedo Filho, Antonio Fernando Barros de, additional, Pazin Filho, Antonio, additional, Timerman, Ari, additional, Scarpa, Bruna Romanelli, additional, Timerman, Bruno, additional, Tavares, Caio de Assis Moura, additional, Martins, Cantidio Soares Lemos, additional, Serrano Junior, Carlos Vicente, additional, Malaque, Ceila Maria Sant'Ana, additional, Pisani, Cristiano Faria, additional, Batista, Daniel Valente, additional, Leandro, Daniela Luana Fernandes, additional, Szpilman, David, additional, Gonçalves, Diego Manoel, additional, Paiva, Edison Ferreira de, additional, Osawa, Eduardo Atsushi, additional, Lima, Eduardo Gomes, additional, Adam, Eduardo Leal, additional, Peixoto, Elaine, additional, Evaristo, Eli Faria, additional, Azeka, Estela, additional, Silva, Fabio Bruno da, additional, Wen, Fan Hui, additional, Ferreira, Fatima Gil, additional, Lima, Felipe Gallego, additional, Fernandes, Felipe Lourenço, additional, Ganem, Fernando, additional, Galas, Filomena Regina Barbosa Gomes, additional, Tarasoutchi, Flavio, additional, Souza, Germano Emilio Conceição, additional, Feitosa Filho, Gilson Soares, additional, Foronda, Gustavo, additional, Guimarães, Helio Penna, additional, Abud, Isabela Cristina Kirnew, additional, Leite, Ivanhoé Stuart Lima, additional, Linhares Filho, Jaime Paula Pessoa, additional, Moraes Junior, João Batista de Moura Xavier, additional, Falcão, João Luiz Alencar de Araripe, additional, Ramires, Jose Antônio Franchini, additional, Cavalini, José Fernando, additional, Saraiva, José Francisco Kerr, additional, Abrão, Karen Cristine, additional, Pinto, Lecio Figueira, additional, Bianchi, Leonardo Luís Torres, additional, Lopes, Leonardo Nícolau Geisler Daud, additional, Piegas, Leopoldo Soares, additional, Kopel, Liliane, additional, Godoy, Lucas Colombo, additional, Tobase, Lucia, additional, Hajjar, Ludhmila Abrahão, additional, Dallan, Luís Augusto Palma, additional, Caneo, Luiz Fernando, additional, Cardoso, Luiz Francisco, additional, Canesin, Manoel Fernandes, additional, Park, Marcelo, additional, Rabelo, Marcia Maria Noya, additional, Malachias, Marcus Vinícius Bolívar, additional, Gonçalves, Maria Aparecida Batistão, additional, Almeida, Maria Fernanda Branco de, additional, Souza, Maria Francilene Silva, additional, Favarato, Maria Helena Sampaio, additional, Carrion, Maria Julia Machline, additional, Gonzalez, Maria Margarita, additional, Bortolotto, Maria Rita de Figueiredo Lemos, additional, Macatrão-Costa, Milena Frota, additional, Shimoda, Mônica Satsuki, additional, Oliveira-Junior, Mucio Tavares de, additional, Ikari, Nana Miura, additional, Dutra, Oscar Pereira, additional, Berwanger, Otávio, additional, Pinheiro, Patricia Ana Paiva Corrêa, additional, Reis, Patrícia Feitosa Frota dos, additional, Cellia, Pedro Henrique Moraes, additional, Santos Filho, Raul Dias dos, additional, Gianotto-Oliveira, Renan, additional, Kalil Filho, Roberto, additional, Guinsburg, Ruth, additional, Managini, Sandrigo, additional, Lage, Silvia Helena Gelas, additional, Yeu, So Pei, additional, Franchi, Sonia Meiken, additional, Shimoda-Sakano, Tania, additional, Accorsi, Tarso Duenhas, additional, Leal, Tatiana de Carvalho Andreucci, additional, Guimarães, Vanessa, additional, Sallai, Vanessa Santos, additional, Ávila, Walkiria Samuel, additional, and Sako, Yara Kimiko, additional

Published
2019
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47. Rational Use of Mechanical Circulatory Support as a Bridge to Pediatric and Congenital Heart Transplantation

Author

Miana, Leonardo A., primary, Rodrigues da Silva, Guilherme Viotto, additional, Caneo, Luiz Fernando, additional, Turquetto, Aída Luisa, additional, Tanamati, Carla, additional, Foronda, Gustavo, additional, Massoti, Maria Raquel, additional, Penha, Juliano G., additional, Azeka, Estela, additional, Galas, Filomena R. B. G., additional, Jatene, Fábio B., additional, and Jatene, Marcelo B., additional

Published
2018
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48. Use of Short-term Circulatory Support as a Bridge in Pediatric Heart Transplantation

Author

Canêo, Luiz Fernando, Miana, Leonardo Augusto, Tanamati, Carla, Penha, Juliano Gomes, Shimoda, Monica Satsuki, Azeka, Estela, Miura, Nana, Galas, Filomena Regina Barbosa Gomes, Guimarães, Vanessa Alves, and Jatene, Marcelo Biscegli

Subjects
Transplante de Coração, Heart Transplantation, Criança, Assisted Circulation, Cardiomiopatias, Cardiomyopathies, Child, Circulação Assistida
Abstract

Background:Heart transplantation is considered the gold standard therapy for the advanced heart failure, but donor shortage, especially in pediatric patients, is the main limitation for this procedure, so most sick patients die while waiting for the procedure.Objective:To evaluate the use of short-term circulatory support as a bridge to transplantation in end-stage cardiomyopathy.Methods:Retrospective clinical study. Between January 2011 and December 2013, 40 patients with cardiomyopathy were admitted in our Pediatric Intensive Care Unit, with a mean age of 4.5 years. Twenty patients evolved during hospitalization with clinical deterioration and were classified as Intermacs 1 and 2. One patient died within 24 hours and 19 could be stabilized and were listed. They were divided into 2 groups: A, clinical support alone and B, implantation of short-term circulatory support as bridge to transplantation additionally to clinical therapy.Results:We used short-term mechanical circulatory support as a bridge to transplantation in 9. In group A (n=10), eight died waiting and 2 patients (20%) were transplanted, but none was discharged. In group B (n=9), 6 patients (66.7%) were transplanted and three were discharged.The mean support time was 21,8 days (6 to 984h). The mean transplant waiting list time was 33,8 days. Renal failure and sepsis were the main complication and causeof death in group A while neurologic complications were more prevalent en group B.Conclusion:Mechanical circulatory support increases survival on the pediatric heart transplantation waiting list in patients classified as Intermacs 1 and 2. Introdução:O transplante cardíaco é o tratamento de escolha na insuficiência cardíaca terminal, porém a escassez de doadores limita o seu emprego, especialmente na população pediátrica. O implante de dispositivos de assistência circulatória mecânica (ACM) pode aumentar o tempo de espera e contribuir na redução da mortalidade.Objetivo:Estudar a evolução dos pacientes pediátricos com diagnóstico de miocardiopatia, com indicação de transplante e que evoluíram em Intermacs1 ou 2, comparando a utilização ou não de algum tipo de ACM de curta duração.Método:No período de janeiro de 2011 a dezembro de 2013, 40 pacientes com idade média de 4,5 anos foram admitidos com diagnóstico de miocardiopatia dilatada. Desses pacientes, 20 evoluíram em Intermacs 1 ou 2. Um faleceu em menos de 24 horas e 19 foram listados para transplante. Os pacientes foram divididos em dois grupos: A, pacientes manejados clinicamente em espera para o transplante; B, pacientes que utilizaram algum tipo de ACM de curta duração durante o tempo de espera em lista.Resultados:No grupo A (n=10), oito pacientes evoluíram para óbito aguardando o transplante e dois pacientes (20%) foram transplantados, sendo que nenhum recebeu alta hospitalar. No grupo B (n = 9), seis pacientes (66,7%; p = 0,04) foram transplantados e três receberam alta hospitalar (p = 0,049). As principais complicações foram insuficiência renal e sepse, no grupo A, e complicações neurológicas no grupo B.Conclusão:O emprego de ACM de curta duração aumentou a sobrevida dos pacientes priorizados e em fila de espera de transplante cardíaco pediátrico.

Published
2014

49. Abstract 13130: The Fontan Immunophenotype and Post-Transplant Outcomes in Children: A Multi-Institutional Study

Author

Mantell, Benjamin S, Azeka, Estela, Cantor, Ryan S, Carlo, Waldemar F, Chrisant, Maryanne, Dykes, John C, Hoffman, Timothy M, Kirklin, James K, Koehl, Devin, L?Ecuyer, Thomas J, McAllister, Jennie M, Prada-Ruiz, Adriana C, and Richmond, Marc E

Abstract

Introduction:Patients (pts) after Fontan palliation often have an altered immunophenotype with lymphopenia (L) and hypogammaglobinemia that may be exacerbated by protein losing enteropathy (PLE, P). These pts represent a growing proportion of the pediatric population requiring heart transplant (Tx). How this altered immunophenotype affects post-Tx outcomes is not well studied.Methods:106 Fontan pts from the Pediatric Heart Transplant Society registry who underwent Tx between 2005-2018, were analyzed. Presence of PLE is coded directly in the registry. Lymphopenia was defined as an absolute lymphocyte count <1000. Impact of L and PLE on graft survival, infection, rejection and malignancy was analyzed at 1-year post-Tx.Results:The following combinations of L and PLE were noted: +L+P, n = 37; +L-P, n = 23; -L+P, n = 10; and -L-P, n = 36. Graft survival between the groups were similar within the first year (+L+P: 86%, +L-P: 86%, -L+P: 87%, -L-P: 89%, p=0.9). Freedom from first infection post-Tx was greater among -L-P pts than pts with either PLE, L, or both (Figure 1); with a 22.1% infection incidence in the -L-P group and 41.4% in all others. These pts had a significantly lower infection rate in the first year after Tx (+L+P: 1.03, +L-P: 1, -L+P: 1.3, -L-P: 0.3 infections/year, p<0.001) and had infection rates similar to a non-single ventricle CHD control group (0.4 infections/year). Neither freedom from rejection (p=0.7) nor freedom from malignancy (p=0.5) 1-year post-Tx, differed among the groups.Conclusions:Fontan pts with altered immunophenotype, as defined by the presence of lymphopenia and/or PLE, are at increased risk of infection post-Tx, although with similar early survival, freedom from rejection and freedom from malignancy. These data may influence post-Tx immunosuppression choice for this growing subset of pts.

Published
2019
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50. The International Society for Heart and Lung Transplantation (ISHLT) guidelines for the care of heart transplant recipients.

Author

Velleca, Angela, Shullo, Michael A, Dhital, Kumud, Azeka, Estela, Colvin, Monica, DePasquale, Eugene, Farrero, Marta, García-Guereta, Luis, Jamero, Gina, Khush, Kiran, Lavee, Jacob, Pouch, Stephanie, Patel, Jignesh, Michaud, CJ, Schubert, Stephan, Angelini, Annalisa, Carlos, Lilibeth, Mirabet, Sonia, Pham, Michael, and Urschel, Simon

Subjects
*HEART transplant recipients, *HEART transplantation, *LUNG transplantation
Published
2023
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