9 results on '"Andersen FB"'
Search Results
2. EE639 Health Care Resource Utilization and Costs Among Persons With a Permanent or Temporary Stoma: A Swedish Register Study
- Author
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Persson, E, primary, Forsmark, A, additional, Sternhufvud, C, additional, Andersen, FB, additional, Scheffel, G, additional, and Carlsson, E, additional
- Published
- 2022
- Full Text
- View/download PDF
3. RWD126 A Comparative Product Consumption Analysis Among New Stoma Appliance Users Utilizing Real-World Evidence
- Author
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Andersen, FB, primary, Snow-Tyler, A, additional, and Håkan-Bloch, J, additional
- Published
- 2022
- Full Text
- View/download PDF
4. POSC393 The Clinical and Economic Burden Imposed By Ileostomy Creation: A Danish Registry Study
- Author
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Andersen, FB, primary, Kjellberg, J, additional, Ibsen, R, additional, Petersen, B, additional, and Sternhufvud, C, additional
- Published
- 2022
- Full Text
- View/download PDF
5. The acute effects of rumen pulse-dosing of hydrogen acceptors during methane inhibition with nitrate or 3-nitrooxypropanol in dairy cows.
- Author
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Maigaard M, Weisbjerg MR, Hellwing ALF, Larsen M, Andersen FB, and Lund P
- Subjects
- Animals, Cattle, Female, Dietary Supplements, Hydrogen, Propanols metabolism, Propanols administration & dosage, Lactation, Milk chemistry, Milk metabolism, Fermentation, Fatty Acids, Volatile metabolism, Rumen metabolism, Methane metabolism, Diet veterinary, Nitrates administration & dosage, Animal Feed, Fumarates pharmacology, Fumarates administration & dosage
- Abstract
Dietary methane (CH
4 ) mitigation is in some cases associated with an increased hydrogen (H2 ) emission. The objective of the present study was to investigate the acute and short-term effects of acceptors for H2 (fumaric acid, acrylic acid, or phloroglucinol) supplemented via pulse-dosing to dairy cows fed CH4 mitigating diets (using nitrate or 3-nitrooxypropanol), on gas exchange, rumen gas, and VFA composition. For this purpose, 2 individual 4 × 4 Latin square experiments were conducted with 4 periods of 3 d (nitrate supplementation) and 7 d (3-nitrooxypropanol supplementation), respectively. In each study, 4 rumen-cannulated Danish Holstein cows were used. Each additive for CH4 mitigation was included in the ad libitum-fed diet within the 2 experiments (exp. 1 and exp. 2), to which the cows were adapted for at least 14 d. Acceptors for H2 were administered twice daily in equal portions through the rumen fistula immediately after feeding of the individual cow. In exp. 1 (nitrate), the treatments were CON-1 (no H2 -acceptor), FUM-1 (fumaric acid), ACR-1 (acrylic acid), and FUM+ACR-1 (50% FUM-1 + 50% ACR-1). In exp. 2 (3-nitrooxypropanol), the 3 treatments, CON-2, FUM-2, and ACR-2, were similar to CON-1, FUM-1 and ACR-1 treatments, however the fourth treatment was PHL-2 (phloroglucinol). Gas exchanges were measured in respiration chambers, and samples of rumen liquid and headspace gas were taken in time series relative to feeding and dosing on specific days. Headspace gas was analyzed for gas composition, and rumen liquid was analyzed for VFA composition and dissolved gas concentrations. Headspace gas composition and dissolved gas concentration were only measured in exp. 2. Dry matter intake was reduced upon acrylic acid supplementation. There were no significant effects of any treatments in any experiments on H2 emission, except for a decrease in hourly H2 emission rate (g/h) at 1 h after feeding in both experiments. In exp. 2, H2 headspace proportions increased with ACR-2 supplementation, whereas dissolved concentrations were unaffected. In exp. 1, cows on ACR-1 increased propionate proportion at 1 h after feeding. In exp. 2, both FUM-2 and ACR-2 increased rumen propionate proportion in the hours after feeding and dosing. There was no effect on rumen acetate for cows on PHL-2. There was a strong positive correlation between rumen dissolved CH4 and headspace CH4 (r = 0.84), whereas the equivalent correlation was weaker for H2 (r = 0.41). For the relationship between dissolved concentrations and emissions of CH4 and H2 , there was a moderate positive correlation for CH4 (r = 0.54), whereas it was weak for H2 (r = 0.28) with zero slope. In conclusion, the results suggested that fumaric acid and acrylic acid to some extent was reduced to propionate without associative effects on measures for H2 redirection. Furthermore, phloroglucinol seemed not to be metabolized in the rumen in the present study, because no effects on rumen acetate or measures of H2 were observed. Changes in H2 headspace and emission may be a poor proxy for actual changes in the rumen fluid concentration of H2 ., (© 2024, The Authors. Published by Elsevier Inc. on behalf of the American Dairy Science Association®. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).)- Published
- 2024
- Full Text
- View/download PDF
6. The clinical and economic burden of illness in the first two years after ostomy creation: a nationwide Danish cohort study.
- Author
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Andersen FB, Kjellberg J, Ibsen R, Sternhufvud C, and Petersen B
- Subjects
- Adult, Humans, Cohort Studies, Cost of Illness, Denmark, Financial Stress, Postoperative Complications, Colorectal Neoplasms surgery, Inflammatory Bowel Diseases surgery, Inflammatory Bowel Diseases complications, Ostomy adverse effects, Scandinavians and Nordic People
- Abstract
Background: Living with an ostomy is often associated with costly complications. This study examined the burden of illness the first two years after ostomy creation., Methods: Data from Danish national registries included all adult Danes with an ostomy created between 2002 and 2014., Results: Four cohorts consisted, respectively, of 11,385 subjects with a colostomy and 4,574 with an ileostomy, of which 1,663 subjects had inflammatory bowel disease (IBD) and 1,270 colorectal cancer as cause of their ileostomy. The healthcare cost was significantly higher for cases versus matched controls for all cohorts. In the first year, the total healthcare cost per person-year was €27,962 versus €4,200 for subjects with colostomy, €29,392 versus €3,308 for subjects with ileostomy, €15,947 versus €2,216 when IBD was the underlying cause, and €32,438 versus €4,196 when it was colorectal cancer. Healthcare costs decreased in the second year but remained significantly higher than controls. Hospitalization and outpatient services were primary cost drivers, with ostomy-related complications comprising 8-16% of hospitalization expenses., Conclusion: Compared to controls, subjects with an ostomy bear a significant health and financial burden attributable to ostomy-related complications, in addition to the underlying disease, emphasizing the importance of better ostomy care to enhance well-being and reduce economic strain.
- Published
- 2024
- Full Text
- View/download PDF
7. Effect of feeding dairy calves with milk fermented with selected probiotic strains on occurrence of diarrhoea, carriage of pathogenic and zoonotic microorganisms and growth performance.
- Author
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Fresno AH, Alencar ALF, Liu G, Wridt MW, Andersen FB, Pedersen HS, Martin HL, Nielsen SS, Aabo S, Olsen JE, and Jensen AN
- Subjects
- Animals, Cattle, Escherichia coli, Milk microbiology, Bacteria, Clostridium perfringens genetics, Feces microbiology, Dairying, Cryptosporidiosis epidemiology, Cryptosporidium, Diarrhea microbiology, Diarrhea veterinary, Cattle Diseases microbiology
- Abstract
Calf-diarrhoea is a major health problem in dairy calves and a primary reason for use of antimicrobials. We aimed to investigate the effect of feeding milk fermented with a combination of four probiotic bacterial strains to young-calves on; occurrence of diarrhoea and associated-pathogens (bacteria, virus and parasites), shedding of Salmonella Dublin and Campylobacter, occurrence of virulence genes linked to Clostridium perfringens, Enterotoxigenic Escherichia coli and shiga-toxin producing E. coli (STEC), as well as growth performance. For this, 143 new-born calves from three Danish dairy-farms were allocated into Treatment- (fed the fermented milk for the first 8-weeks-of-life) and Control-groups (fed regular farm-milk). Diarrhoea was observed in 18.6 % (Farm 1), 22.4 % (Farm 2) and 15.7 % (Farm 3) of the total registrations mainly within the first 3-weeks-of-life. C. perfringens was the most frequently detected pathogen. The treatment did not affect the occurrence of virulence genes linked to STEC and C. perfringens and, overall, their detection levels were very low/undetected. The statistical model applied found no significant effect of the treatment on prevalence of early-diarrhoea (≤ 3 weeks), late-diarrhoea (>3 weeks), occurrence of C. perfringens and Cryptosporidium parvum or levels of Campylobacter spp. Limited detection of the other pathogens and associated virulence-genes under study, did not allow for assessment of the impact of the treatment on their occurrence. Notably, the feeding-approach showed a significant detrimental effect on daily-weight-gain. The inefficacy of the treatment may be associated with the complexity of influencing factors under field conditions including management practices., Competing Interests: Declaration of Competing Interest The authors declare the following financial interests/personal relationships which may be considered as potential competing interests: Annette N Jensen reports financial support was provided by GUDP Development and Demonstration Program under the Ministry of Food, Agriculture and Fisheries of Denmark. Co-author H. S. Pedersen is employed by Calvex A/S who is offering feeding strategy consultations and solutions for the cattle industry., (Copyright © 2023 Elsevier B.V. All rights reserved.)
- Published
- 2023
- Full Text
- View/download PDF
8. The prevalence of workaholism: a systematic review and meta-analysis.
- Author
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Andersen FB, Djugum MET, Sjåstad VS, and Pallesen S
- Abstract
The present study represents the first meta-analysis and systematic review on the prevalence of workaholism. It also investigated if sample size, representativeness, and instrument moderated the prevalence estimates. The analysis was pre-registered at PROSPERO (CRD42023395794). We searched Web of Science, PubMed, CINAHL, Embase, PsychInfo. BASE, MedNar, NYAM, OPENGREY, OpenMD and included the first 200 searches on Google scholar as gray literature [search string: "(workaholi* OR "work addict*") AND (prevalence* OR incident* OR frequen* OR cut-off OR epidem*)]. The search yielded 42 studies to be included, in addition to 11 studies identified using other methods. Two independent raters went through the searches, extracted information and evaluated risk of bias, resulting in agreement ratings of 92.4%, 84.9%, and 87.0%, respectively. The inclusion criteria were studies reporting original data on the prevalence of workaholism written in any European language. Criteria which led to exclusion were conference abstracts, usage of secondary data, purposive sampling of workaholics, qualitative research and pre-determined cut-off based on distribution. Risk of bias of the included articles was evaluated through a checklist. Most of the included studies had a moderate risk of bias. Of the 663 records identified, a total of 53 studies were included, 10 of these being nationally representative with all studies in total amounting to 71,625 participants from 23 countries. The pooled workaholism prevalence was 15.2% (95% CI = 12.4-18.5), which was adjusted to 14.1% (95% CI = 11.2-17.6) following a trim-and-fill adjustment for publication bias. The meta-regression revealed that studies with representative samples reported lower prevalences than those based on non-representative samples, and that studies based on the Dutch Work Addiction Scale yielded higher prevalences than studies employing the Bergen Work Addiction Scale. The regression model explained 29% of the variance implying that a vast amount was still unexplained, and that future research would benefit from the inclusion of other moderators., Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest., (Copyright © 2023 Andersen, Djugum, Sjåstad and Pallesen.)
- Published
- 2023
- Full Text
- View/download PDF
9. Short- and long-term direct and indirect costs of illness after ostomy creation - a Swedish nationwide registry study.
- Author
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Carlsson E, Forsmark A, Sternhufvud C, Scheffel G, Andersen FB, and Persson EI
- Subjects
- Humans, Sweden epidemiology, Retrospective Studies, Cost of Illness, Registries, Ostomy
- Abstract
Background: Despite advance in care of people with an ostomy, related complications remain prevalent. The objective of this study was to examine short- and long-term healthcare resource utilization and associated costs after ostomy creation., Methods: This observational study was based on retrospectively collected data from national and regional Swedish registries. The population consisted of people living in Sweden, who had an ostomy created. The earliest index date was 1 January 2006, and people were followed for ten years, until death, reversal of temporary ostomy, termination of purchases of ostomy products, or end of study, which was 31 December 2019. Each person with an ostomy was matched with two controls from the general population based on age, gender, and region., Results: In total, 40,988 persons were included: 19,645 with colostomy, 16,408 with ileostomy, and 4,935 with urostomy. The underlying diseases for colostomy and ileostomy creations were primarily bowel cancer, 50.0% and 55.8% respectively, and additionally inflammatory bowel disease for 20.6% of ileostomies. The underlying cause for urostomy creation was mainly bladder cancer (85.0%). In the first year after ostomy creation (excl. index admission), the total mean healthcare cost was 329,200 SEK per person with colostomy, 330,800 SEK for ileostomy, and 254,100 SEK for urostomy (100 SEK was equivalent to 9.58 EUR). Although the annual mean healthcare cost decreased over time, it remained significantly elevated compared to controls, even after 10 years, with hospitalization being the main cost driver. The artificial opening was responsible for 19.3-22.8% of 30-day readmissions after ostomy creation and for 19.7-21.4% of hospitalizations during the entire study period. For the ileostomy group, dehydration was responsible for 13.0% of 30-day readmissions and 4.5% of hospitalization during the study period., Conclusions: This study reported a high disease burden for persons with an ostomy. This had a substantial impact on the healthcare cost for at least ten years after ostomy creation. Working ability seemed to be negatively impacted, indicated by increased cost of sickness absence and early retirement. This calls for improved management and support of ostomy care for the benefit of the affected persons and for the cost of society., (© 2023. BioMed Central Ltd., part of Springer Nature.)
- Published
- 2023
- Full Text
- View/download PDF
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