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The article offers information on how Covid-19 pandemic oral-associated lesions. It mentions that cytokine release syndrome (CRS), seen in COVID-19 patients, presents in association with immune dysregulation and tissue damages, especially at the oral and nasal mucosa. It discusses the use of telemedicine for managing dental emergencies and for minimizing the contact between the patients and the clinicians in Covid-19 pandemic.

The article presents several case study related to 56-year-old healthy male patient without any relevant medical history was isolated with suspected infection of SARS-CoV-2, 58-year-old male patient with diabetes and hypertension reported pain on his palate, and 65-year-old female patient developed high fever, diarrhea, and pain on her tongue on March 12, 2020. Topics include the humans has infected with SARS-CoV-2 are at risk of developing serious and life-threatening conditions.