1. A Primary Investigation on Serum CTX-II Changes in Patients Infected with Brucellosis in Qinghai Plateau, China.
- Author
-
ZHAO, Zhi Jun, LI, Qiang, ZHOU, Xin, MA, Li, XU, Li Qing, YANG, Pei Zhen, MENG, Xian Ya, YU, Hui Zhen, XU, Xiao Qing, and CAO, Jian Ying
- Subjects
DIAGNOSIS of brucellosis ,CHOLERA toxin ,SERUM ,SEROLOGY ,DISEASE complications ,ENZYME-linked immunosorbent assay - Abstract
Brucellosis is one of the most widespread zoonotic diseases, with the most frequent complication being osteoarticular changes. The aim of this study was to assess the changes of C-terminal telopeptide of type II collagen (CTX-II) in patients infected with brucellosis. A total of 84 brucellosis patients and 43 volunteers were selected and divided into brucellosis vs. control groups. Serum samples were subjected to serological tests for brucellosis, and CTX-II levels in all samples were measured simultaneously with ELISA. The results showed that serum CTX-II levels in human brucellosis were higher than those of healthy controls, without a statistically significant difference, but serum CTX-II levels in male patients were significantly higher than those of female patients ( P <0.05). This finding could indicate the biological changes in the cartilage and bone in human brucellosis. [ABSTRACT FROM AUTHOR]
- Published
- 2016
- Full Text
- View/download PDF