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Introduction: Advancements in monoclonal antibodies, tyrosine kinase inhibitors, and antibody drug conjugates (ADCs) have notably enhanced outcomes for metastatic HER2-positive breast cancer patients. Despite the expanding treatment options and clinical complexities, determining the optimal sequence of HER2-targeted therapies remains partly uncertain, influenced by various factors., Methods: To refine HER2-positive metastatic breast cancer management, particularly regarding tucatinib's position, a Steering Committee of leading oncologists in breast cancer care devised a panel of statements via a Delphi approach, focusing on five key topics: general clinical management, therapeutic approaches for patients with HER2-positive breast cancer and brain metastases, treatment sequence, and tucatinib's safety and efficacy., Results: A total of 29 statements were deliberated, with strong consensus achieved for most. However, no consensus emerged regarding the management of brain progression alongside stable extracranial disease: 48 % advocated for switching to tucatinib, while 53 % favored a stereotactic brain radiotherapy (SBRT) approach if feasible., Conclusion: The unanimous consensus attained in this Delphi panel, particularly regarding tucatinib's efficacy and safety, underscores oncologists' recognition of its clinical significance based on existing trial data. These findings align closely with current literature, shedding light on areas necessitating further investigation, not thoroughly explored in prior studies. Moreover, the results underscore the scarcity of data on managing brain progression alongside stable extracranial disease, emphasizing the imperative for dedicated research to address these gaps and yield definitive insights., Competing Interests: Declaration of competing interest PC: Consulting or Advisory Role: Daiichi Sankyo/Lilly, Reveal Genomics, Gilead Sciences; Speakers' Bureau: Roche/Genentech, Novartis, AstraZeneca, Lilly, BMS; Research Funding: Merck KGaA (Inst); Patents, Royalties, Other Intellectual Property: HER2Dx patent; Expert Testimony: AstraZeneca. EC: reports consulting fees from Novartis, Lilly, Pfizer, Roche, AstraZeneca, and Daiichi Sankyo; speaker's bureau from Lilly, Pfizer, AstraZeneca, and Daiichi Sankyo; and travel and accommodations from Pfizer and Roche. GC: received honoraria for speaker's engagement: Roche, Seattle Genetics, Novartis, Lilly, Pfizer, Foundation Medicine, NanoString, Samsung, Celltrion, BMS, MSD; Honoraria for providing consultancy: Roche, Seattle Genetics, NanoString; Honoraria for participating in Advisory Board: Roche, Lilly, Pfizer, Foundation Medi-cine, Samsung, Celltrion, Mylan; Honoraria for writing engagement: Novartis, BMS; Honoraria for participation in Ellipsis Scientific Affairs Group; Institutional research funding for conducting phase I and II clinical trials: Pfizer, Roche, Novartis, Sanofi, Celgene, Servier, Orion, AstraZeneca, Seattle Genetics, AbbVie, Tesaro, BMS, Merck Serono, Merck Sharp Dome, Janssen-Cilag, Philogen, Bayer, Medivation, MedI- mmune MDL: advisory boards, activities as a speaker, travel grants, consultancy: Eli Lilly, Novartis, Seagen, Takeda, Roche, Daiichi Sankyo, Tomalab, Gilead, Genetic, Menarini, Sophos, AstraZeneca, Pfizer, Sanofi, Ipsen, Pierre Fabre, GSK. AG: research funding to the Institution: AstraZeneca, Pfizer, Janssen, Roche, MSD, Daichii-Sankyo, GSK/Tesaro, HiFiBio, Merck, Boehringer-Ingelheim, Exelixis, Bayer, Incyte, Bayer, Aileron; travel, accommodation, expenses: Gentili. LDM: advisory role for Agendia, Amgen, AstraZeneca, Collage SpA, Daiichi Sankyo, Eli Lilly, Exact Sciences, Gilead, GSK, Havas Life, Pfizer, Pierre Fabre, Roche, Seagen Int, Stemline Menarini and Uvet; personal fees as an invited speaker for Accademia Nazionale Medicina, Andromeda E20, Aristea, Delphi international, Editree, Eli Lilly, Ipsen, Meeting SrL, MSD, Novartis, Over Srl, Prex Srl, Symposia and Vyvamed Srl; personal fees for writing engagements for Edizioni Minerva Medica, Pensiero Scientifico Editore and Roche; personal consultancy fees from Eli Lilly, Gilead, Kardo Srl and Sharing Progress in Cancer Care (SPCC)—Switzerland; personal fees for author slide kits from Forum service and Think2it; personal fees for interviews from Infomedica Srl and Think2it; institutional funding as a local PI from AstraZeneca, Daiichi Sankyo, Eli Lilly, Gilead, Novartis, Novella Clinical, Roche and Seagen; institutional funding as a national coordinating PI from Roche; institutional research grant from Pfizer; and non-remunerated product samples from FoundationOne. AG: received advisory role from AstraZeneca, Daiichi, Eisai, Lilly, Novartis, Pfizer, Roche, Seagen, Gilead, Teva, and Gentili; lecture honoraria from Novartis, Pfizer, Gilead, Roche, Eisai, Seagen, Teva, and Gentili; and research support from Roche, Eisai, Gilead, and Pharmanutra AL: Research support: Roche, Agendia, Lilly, Pfizer, Novartis, Merck Sharp&Dhome, Gilead, Daiichi Sankyo; Consulting/advisor: Lilly, Roche, Pfizer, Novartis; Speaker's Bureaus: Lilly, Astrazeneca, Merck Sharp&Dhome, Pfizer, Novartis; Travel support: Roche, Pfizer, Astrazeneca, Merck Sharp&Dhome. MM: Honoraria: Roche/Genentech, Lilly, Pfizer, Novartis, Pierre Fabre, Seagen; Consulting or Advisory Role: Roche/Genentech, Novartis, Pfizer, Lilly, AstraZeneca, Daiichi-Sankyo; Speakers' Bureau: Lilly/ImClone, Lilly/ImClone, Roche/Genentech, Pierre Fabre; Research Funding: Novartis (Inst), Roche (Inst), Puma Biotechnology (Inst); Travel, Accommodations, Expenses: Daiichi-Sankyo; Other Relationship: Roche, Novartis. FPo: advisory board from AstraZeneca; speaking honoraria and travel grants from Eli Lilly, Novartis, Seagen, Daichii Sankyo, and Gilead. AP: reports grants and personal fees from NanoString Technologies, Veracyte, Novartis, AstraZeneca, DaiichiSankyo, and Roche; in addition, A. Prat has a patent for DNADX pending. FPu: reports honoraria for advisory boards, activities as a speaker, travel grants, research grants from Amgen - Astrazeneca - Daiichi Sankyo - Celgene - Eisai - Eli Lilly- Exact Sciences- Gilead - Ipsen – Menarini- MSD - Novartis - Pierre Fabre - Pfizer - Roche - Seagen - Takeda – Viatris; Research funding from Astrazeneca – Eisai – Roche. CS: consultancy or advisory role for AstraZeneca, Ax's Consulting, Byondis, Daiichi Sankyo, Eisai, Exact Sciences, Exeter, F. Hoffmann-La Roche Ltd., International Society for the Study and Exchange of evidence from Clinical research And Medical experience (ISSECAM), Medical Statistics Consulting, MediTech, Merck Sharp and Dohme Corp, Novartis, Pfizer, Philips, Pierre Fabre, PintPharma, Puma, Roche, Sanofi, Seagen, Zymeworks, and research funding from Aragon, AstraZeneca, Bayer, Boehringer Ingelheim, Bristol Myers Squibb, Byondis, CytomX, Daiichi Sankyo, F. Hoffmann-La Roche Ltd., Genentech, German Breast Group Forchungs, GlaxoSmithKline, Immunomedics, Innoup, International Breast Cancer Study Group (IBCSG), Lilly, Macrogenics, Medica Scientia Innovation Research, Menarini Ricerche, Merck Sharp and Dohme Corp, Merus, Millennium, Novartis, Pfizer, Piqur, Puma, Roche, Sanofi, Seagen, Synthon, and Zenith., (Copyright © 2024 The Author(s). Published by Elsevier Ltd.. All rights reserved.)

Chicken meat is well known for its high nutritional value. Its shelf life is short, due to the pronounced perishability, even under refrigeration. Paper bags are usually used as packaging materials, due to their biodegradability. The main negative aspect concerning paper is its high porosity and low moisture barrier. In this regard, it has to be coated/modified with efficient moisture barrier materials. The storage of chicken breast meat wrapped in four types of paper‐based materials currently in use in Romania (RO), Italy (IT), Spain (SP) and Slovenia (SLO) is reported. RO and IT are paper coated with polyethylene (PE) film, SP is waxed paper, and SLO is paper modified with hydrophobized starch. The influence of the coating film on the organoleptical, biochemical and microbiological characteristics of the chicken breast meat stored at 4°C was the aim of the study. The mathematical modelling revealed two aspects: (1) the stability period in which the meat safe for consumption is in the range 1.92–2.18 days in the case of all paper types, and (2) cadaverine, the amine generated by protein degradation, is a less sensitive indicator of the meat alteration than microbial growth. The papers coated with PE (RO and IT samples) and with hydrophobized starch (SLO paper) were packaging materials more efficient that the waxed paper (SP sample). The polyethylene film reduced the conversion of putrescine into spermidine in a higher extent than wax. [ABSTRACT FROM AUTHOR]

Objective: The aim of this study was to explore the geographic distribution and number of papers published in international and Science Citation Index (SCI)-indexed cytology journals based on their country of origin., Materials and Methods: A country-based geographic analysis of studies published over a 5.5-year period from January 2016 to June 2021 in 5 cytopathology journals indexed as SCI and SCI-E with an impact factor higher than 1 (Cancer Cytopathology, Cytopathology, Diagnostic Cytopathology, Acta Cytologica, and CytoJournal) and papers categorized as "original" and "other" was performed., Results: A total of 3,063 papers were found, with 1,466 (47.8%) categorized as "original" papers and 1,597 (52.1%) designated as "other" papers. These papers were submitted from 62 different countries. The five countries with the greatest number of papers were the USA (38.4%), India (16.8%), Japan (7.4%), Italy (5.5%), and Brazil (3.1%). A general subgroup analysis was also performed on the original studies without a country breakdown. Cytomorphological, cytomorphological-immunohistochemical, and molecular assessments compose 38.5%, 45.7%, and 15% of the subgroups, respectively., Conclusion: The number of academic papers originating from developing countries in the field of cytopathology has increased in recent years. Although most scientific papers are produced in developed countries, the rate in these countries is much lower than that in some developing countries as the rate of academic growth in developed countries has stabilized. Despite the widespread and sophisticated implementation of cytology in daily practice in Western European countries outside the UK, such as Germany and the Netherlands, and in Scandinavian countries and other developed countries, such as Australia and Canada, these countries rank in the middle to lower end of countries producing cytology papers. Meanwhile, there has been an increase in the number of cytology papers published by authors from Southern European countries, such as Italy (ranked 4th) and Spain (ranked 6th), and Turkey (ranked 8th). There is a remarkable increase in cytology papers originating from Asia, particularly India, Japan, and China., Summary: We aimed to present a basic survey of the geographic distribution of manuscript submissions to high-impact cytopathology journals and to point out emerging trends in cytology utilization and basic research. However, our results show that the landscape of cytology is changing and suggest geographic regions that are ripe for the production of novel "points of view" and new research findings., (© 2022 S. Karger AG, Basel.)

The aim of the study was to perform dimensional, morpho-structural, mechanical and chemical characterization of four materials based on paper currently in use in Romania (RO), Italy (IT), Spain (SP) and Slovenia (SLO) designed for the temporarily wrapping of meat. SEM-EDXS, FTIR and DSC showed that RO is laminated on one side with polyethylene, SP is waxed, IT is modified with a multilayered polyethylene film and SLO is coated with hydrophobized starch. RO, IT and SLO comply with the standards of determination of density, roughness, breaking length and bending resistance. The highest content of metals found in the SP explains the highest electrical conductivity and the poor quality of the recycled material used for manufacturing. The highest values of total dissolved solids (TDS) and chemical oxygen demand (COD) resulted for SP sample expressed its water solubility and availability of migration into foodstuff. RO, IT and SLO are suitable for food packaging. In contrast, SP do not meet the requirements for safety and mechanical resistance. [Display omitted] • Characterization of four types of materials based on paper. • RO, IT-single-face coated with PE, SP-double-side waxed, SLO-coated with starch. • RO, IT, SLO comply the standards of mechanical resistance and are suitable for food packaging. • SP do not meet the requirements for safety and mechanical resistance. [ABSTRACT FROM AUTHOR]

Individuals who reside in a country without regular authorisation generally find it difficult to access public medical services beyond emergency treatment. Even in countries with universal healthcare, there is often a gap between rights on paper and their implementation. Civil society organisations (CSOs) fill this gap by providing medical services to vulnerable populations, including irregular migrants. What, if any, are the ethical dilemmas that arise for CSO staff when delivering such services in countries with universal healthcare? Under what conditions do these dilemmas arise? And what strategies do CSO staff use to mitigate them? We answer these questions using 40 semi-structured interviews with CSO staff working in two European countries with high levels of irregularity, universal healthcare provisions on paper, and significant differences in approaches and availability of public services for irregular migrants: Italy and Spain. We show that CSO staff providing medical services to irregular migrants in places with universal healthcare coverage face a fundamental dilemma between humanitarianism and equity. CSO staff respond to the humanitarian belief in the value of taking all possible steps to prevent or alleviate human suffering, thus promoting a decent quality of life that includes access to both emergency and non-emergency care. In doing so, however, they run the risk of substituting rather than complementing public provisions, thereby preventing governments from assuming responsibility for these services in the long term. Individuals who acknowledge the existence of this dilemma generally oppose the creation of parallel structures; that is, services specifically developed for irregular migrants outside the public system; while those who ignore it essentially subscribe to a tiered system, giving up on considerations of equity. We argue that CSOs involved in the provision of healthcare to irregular migrants do not simply provide services; they also play an inherently political role. [ABSTRACT FROM AUTHOR]

Purpose: The Comprehensive assessment of Acceptance and Commitment Therapy (CompACT) is a 23-item questionnaire measuring psychological flexibility, a quality of life protective factor. An 18-item version was recently produced. We assessed validity and reliability of CompACT, and equivalence of paper and electronic (eCompACT) versions in people with multiple sclerosis (PwMS) in Italy, Germany and Spain. Methods: We used confirmatory factor analysis and assessed CompACT-23 and CompACT-18 measurement invariance between the three language versions. We assessed construct validity (Spearman's correlations) and internal consistency (Cronbach's alpha). Test–retest reliability (intraclass correlation coefficient, ICC) and equivalence of paper and eCompACT (ICC and linear regression model for repeated measures) were assessed in subsamples of PwMS. Results: A total of 725 PwMS completed the study. The three-factor structure of the CompACT-23 showed poor fit (RMSEA 0.07; CFI 0.82; SRMR 0.08), while the fit of the CompACT-18 was good (RMSEA 0.05; CFI 0.93; SRMR 0.05). Configural and partial metric invariance were confirmed, as well as partial scalar invariance (reached when five items were allowed to vary freely). The CompACT-18 showed good internal consistency (all alpha ≥ 0.78); and test–retest reliability (all ICCs ≥ 0.86). Equivalence between paper and eCompACT was excellent (all ICCs ≥ 0.86), with no mode, order, or interaction effects. Conclusion: Results support using the refined CompACT-18 as a three-factor measure of psychological flexibility in PwMS. Paper and eCompACT-18 versions are equivalent. CompACT-18 can be used cross-culturally, but sub-optimal scalar invariance suggests that direct comparison between the three language versions should be interpreted with caution. [ABSTRACT FROM AUTHOR]

This paper presents a meta-analysis of 29 studies run using the Mind Genomics approach to quantify how respondents react to messaging and how their reaction impacts decision-making in social psychology experimental research areas. The Mind Genomics studies used were performed during the 2020-2022 period in the USA, Italy, Spain, Albania, and other countries of the Mediterranean basin. The paper focuses on identifying gender differences in response time and evaluations of messages on different topics calculated by the Mind Genomics-Artificial Intelligence system. Further, the meta-analysis results are based on Kahneman's (2011) study results. The study's general result demonstrates that male and female participants' thinking is intuitive, automatic, and emotionally oriented. The study also confirms that the gender's response time does not affect the results of the experiment. In addition, is argued that genderbased perceptions differ according to the topic and are considered relevant in decision-making on some topics. These study results can be used to predict the experiment's results for new participants without having them repeat the entire experimental procedure. [ABSTRACT FROM AUTHOR]

Citation networks enable analysis of author groups, defining in-group dynamics, and mapping out inter-group relationships. While intellectual diversity and inclusiveness is one of the important principles of modern scholarship, it is intriguing to explore the extent to which these principles apply to historical communities of leaders and intellectuals. This paper introduces a novel methodological framework aimed at assessing the degree of viewpoint plurality and diversity of historical scholarship communities, through an in-depth analysis of the citations used in their literature, which has become possible due to the recently developed advanced computational analysis techniques. To achieve this goal, we have devised a set of new network-based indicators grounded in standard network metrics. These indicators can be applied at both the individual author and community levels. The developed methodology was applied to a citation network automatically constructed from a corpus of Rabbinic Halachic literature spanning the 10th to 15th centuries. This corpus includes over 5,000 citations from hundreds of books authored by approximately 140 Rabbinic scholars from six diverse geographic communities. We found that most of the authors and communities cite many more external resources from other communities than their own reflecting a willingness to engage with a diverse range of viewpoints. A more in-depth analysis based on the novel proportional diversity measures unveils more intriguing insights. Contrary to expectations, communities with the greatest number of external citations, such as Spain and Ashkenaz, surprisingly exhibit lower levels of viewpoint plurality compared to others, such as Italy and North Africa, elucidating a key finding of the study. [ABSTRACT FROM AUTHOR]

Purpose: This paper aims to test the existence of the so-called industrial district effect on innovation (iMID effect) in Spain and Italy and to compare the intensity of this effect between both countries. There is previous evidence of this effect for Spain, although, to the best of the authors' knowledge, it has never been measured for Italy. Design/methodology/approach: Innovation intensity by local production system is measured using patents per million employees and analysed using the mean, the median, 3D maps and statistical tests. Findings: Industrial districts generate between a third and a quarter of all technological innovations in Spain and Italy. The evidence about the district effect in innovation in Spain is consistent with previous studies. The novelty is that there is also evidence of this effect for Italy and its intensity is higher than for Spain. Almost one-half of the industrial districts fit in the most innovative quartile of local production systems, and they are located in the most innovative part of each country. Research limitations/implications: Limitations of this study include minor database issues. Implications include new focus on the general relevance of industrial districts as highly innovative local production systems and top innovators. Practical implications: Reorientation of territorial and innovation policies. Social implications: Effect on development and well-being through technical progress. Originality/value: This article provides, for the first time, to the best of the authors' knowledge, a measurement of the industrial district effect on innovation in Italy. The paper compares the results between Spain and Italy and allows for generalization of previous evidence, concluding that highly innovative industrial districts are not "rare diamonds", revealing as an alternative and an extraordinarily powerful place-based innovation model. [ABSTRACT FROM AUTHOR]

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Background: Mild cognitive impairment (MCI) is commonly defined as a transitional subclinical state between normal aging and dementia. A growing body of research indicates that health behaviors may play a protective role against cognitive decline and could potentially slow down the progression from MCI to dementia. The aim of this study is to conduct a bibliometric analysis of literature focusing on health behaviors and MCI to summarize the factors and evidence regarding the influence of health behaviors on MCI. Methods: The study performed a bibliometric analysis by retrieving publications from the Science Citation Index and Social Sciences Citation Index subdatabases within the Web of Science Core Collection. Utilizing VOSviewer and CiteSpace software, a total of 2,843 eligible articles underwent co-citation, cokeywords, and clustering analyses. This methodology aimed to investigate the current status, trends, major research questions, and potential future directions within the research domain. Results: The bibliometric analysis indicates that research on healthy behaviors in individuals with MCI originated in 2002 and experienced rapid growth in 2014, reflecting the increasing global interest in this area. The United States emerged as the primary contributor, accounting for more than one-third of the total scientific output with 982 articles. Journals that published the most articles on MCI-related health behaviors included "Journal of Alzheimer's Disease," "Neurobiology of Aging," "Frontiers in Aging Neuroscience," and other geriatricsrelated journals. High-impact papers identified by VOSviewer predominantly cover concepts related to MCI, such as diagnostic criteria, assessment, and multifactorial interventions. Co-occurrence keyword analysis highlights five research hotspots in health behavior associated with MCI: exercise, diet, risk factors and preventive measures for dementia, cognitive decline-related biomarkers, and clinical trials. Conclusion: This study provides a comprehensive review of literature on health behavior in individuals with MCI, emphasizing influential documents and journals. It outlines research trends and key focal points, offering valuable insights for researchers to comprehend significant contributions and steer future studies. [ABSTRACT FROM AUTHOR]

In the context of climate change, it is important to monitor the dynamics of the Earth's surface in order to prevent extreme weather phenomena such as floods and droughts. To this end, global meteorological forecasting is constantly being improved, with a recent breakthrough in deep learning methods. In this paper, we propose to adapt a recent weather forecasting architecture, called GraphCast, to a water resources forecasting task using high-resolution satellite image time series (SITS). Based on an intermediate mesh, the data geometry used within the network is adapted to match high spatial resolution data acquired in two-dimensional space. In particular, we introduce a predefined irregular mesh based on a segmentation map to guide the network's predictions and bring more detail to specific areas. We conduct experiments to forecast water resources index two months ahead on lakes and rivers in Italy and Spain. We demonstrate that our adaptation of GraphCast outperforms the existing frameworks designed for SITS analysis. It also showed stable results for the main hyperparameter, i.e., the number of superpixels. We conclude that adapting global meteorological forecasting methods to SITS settings can be beneficial for high spatial resolution predictions. [ABSTRACT FROM AUTHOR]

The Mediterranean Basin is one of the World's plant diversity hotspots and a region prone to several anthropic pressures, besides being one of the World's areas most susceptible to climate change. In this region, which hosts a high percentage of threatened species, there has been a large increase in practical conservation actions to prevent the extinction of many plants or improve their conservation status. In this framework, plant translocations have become increasingly important. To obtain a picture of the status and to depict possible directions, data on plant translocations was collected through the available databases, national experts, and the grey literature available online. Overall, a list of 836 translocations relating to 572 plant species was found. These actions are mainly concentrated in Spain, France, and Italy (c. 87%) and, except for some pioneering actions, translocations have strongly increased starting from 2010. A subsequent in-depth bibliographic search of the scientific databases was conducted to determine how much information about plant translocations was documented in the scientific literature. This search resulted in a list of 133 peer-reviewed papers, of which only 17 describing one or more translocations and, as a whole, reporting 101 experiences carried out on 56 plant species. Our research highlighted a great discrepancy between the scarce scientific documentation in comparison to the large number of practical conservation actions carried out. The great experience gained in these translocations constitutes an enormous heritage potentially available to implement the necessary conservation actions to preserve the plant diversity of the Mediterranean Basin. [ABSTRACT FROM AUTHOR]

This paper explains the logic for using the concept of gender-related violence (GRV) as a broad category that problematises homophobia, transphobia and the policing of gender norms and the gender binary, as well as gender-based violence—understood as primarily violence against women and girls (VAWG). It then evaluates the utility of this concept and its capacity to introduce theoretical refinement to the study of gendered violence, by reviewing its reception within a large international feminist project on gendered violence in the lives of children and young people. The aim of this study was to improve knowledge and understanding of forms of violence and discrimination among practitioners who have everyday contact with general populations of children and young people. It sought to improve their ability to identify and challenge sexist, sexualising, homophobic or transphobic language or behaviour, and their knowledge of how and when to refer children and young people to appropriate support. The paper reports my view of the contribution that the concept of gender-related violence made in each of the four project sites: Ireland, Italy, Spain and the UK. The findings are mixed: in Spain and the UK the concept seemed helpful, but in Italy and Ireland it was initially expected to be helpful but, in practice, a conceptualisation closer to gender-based violence plus homophobia was employed. It is tentatively concluded that where LGBTQIA+ rights were well-established as well as the problematisation of VAWG, this framework was successful, but that it was less successful in more heteronormative sites where homophobia was less problematised. It is suggested that, as a concept, GRV can make a valuable intervention in sites like the former. [ABSTRACT FROM AUTHOR]

The central objectives of this paper are to enhance the understanding of how consumers in developed economies value credence attributes and to understand their preferences for red-pulp kiwifruit. To achieve this, we utilised the choice experiment method through surveys conducted in Italy, Spain, France, and Germany, targeting kiwifruit consumers through specific questionnaires. Regarding red kiwifruit, a significant percentage of those who are already familiar with them either purchase or intend to purchase them. What is equally interesting is the high percentage of those who declared themselves to be undecided about making a purchase. Specific marketing actions can be directed towards the following two categories: converting the intention to purchase into an actual purchase and shifting the current inclination towards an intention or act of purchase, for example, by improving the knowledge about this relatively unknown fruit. This paper contributes to the market chain by assessing consumers' choice and willingness to pay for red kiwifruit, while also comparing developed economy markets. [ABSTRACT FROM AUTHOR]

As humanity reaches the 5.0 industrial revolution, education plays a critical role in boosting the quality of human resources. This paper reports bibliometric research on emerging TiP during 1993-2022 in the educational field to analyse its development on any level of education during the last three decades. This study employed a Scopus database. The findings are that the trend of TiP publication in educational fields has tended to increase every year during the past three decades and conference paper became the most published document type, the USA is the country which produces the most publications; "Students" being the most occurrences keyword and total link strength. The publication of the TiP is ranked to the Quartile 1, which implies that a publication with the cited performance is a publication with credibility because the publisher has a good reputation. Researchers can find the topics most relevant to other metadata sources such as Web of Science, Publish, and Perish.

The present study aims to identify the most productive countries, journals, authors, institutions and the most used keywords in the field of special education during 2011-2020, based on the WoS database. The widespread effects of the papers and how they are related were analyzed with the bibliometric analysis method. The findings of the study showed that the USA is inarguably the most productive country, followed by England and Australia. On the other hand, there was a very strong positive correlation (r = 0.929) between the number of papers published by countries and their h-index, a similar finding was also found to be present between the countries' h-index and GDP per capita (r = 0.790). Moreover, it was found that the journals with the highest quartile (Q1 and Q2) in the field of special education published significantly more papers than the journals with the lowest quartile (Q3 and Q4). Matson, JL (USA), Sigafoos, J (New Zealand) and Lancioni, GE (Italy) were determined as the most prolific authors, respectively. Autism, intellectual disability, and Down syndrome were the phrases most frequently used as keywords. Our findings provide key information regarding the developments that the research direction of special education field has recently taken. This study also serves a potential roadmap for future studies.

Purpose: This study aims to investigate how institutional and organisational factors affect case management of patients with mental disorders by GPs in Italy and Spain. The paper highlights the importance of improving the effectiveness of primary care to ensure easy access to mental health services, which is crucial in responding to the increasing incidence of mental disorders and preventing negative outcomes. Design/methodology/approach: This article details a qualitative research study that examines the management of patients with mental disorders by general practitioners (GPs) in Italy and Spain, using cross-national comparison and in-depth interviews with GPs as research methods. Findings: The study revealed that Italian self-employed GPs have more scheduling autonomy than Spanish Health Centre GPs. Both face high work pressure and resource scarcity, highlighting the need for targeted training. The COVID-19 pandemic led to a rise in phone consultations. Originality/value: This study provides novel insights into mental health management by examining the case management of patients with mental disorders by GPs in Italy and Spain, with a focus on the impact of institutional and organisational factors. The cross-national comparison and in-depth interviews enhance the originality of the study, offering a nuanced understanding of the constraints faced by GPs in their work context. Furthermore, the comparison of the similar primary care frameworks of Italy and Spain may offer insight into their evolution. [ABSTRACT FROM AUTHOR]

The EU legislature, through the approval of the Non-financial Information Directive, has made a decisive step towards a mandatory regime for Sustainability Reporting as an essential condition to promote sustainable behavior across European countries. This paper aims at examing the impact of managers' beliefs and attitudes on NFI mandatory reporting practices through the Theory of Planned Behavior. We test whether managers' attitudes, subjective norms, and perceived behavioral control impact the quality of sustainability reports in Spain and Italy. We built a reflective-formative hierarchical component PLS-SEM model, tested in a survey of 104 Italian (56.73%) and Spanish (43.27%) managers, that combines different latent variables and their relationships, which confirms all our hypotheses. This cross-country analysis is motivated by some differences between Italy and Spain in their cultural orientation and in the area non-financial reporting. To measure Non-financial Information, we crafted a Sustainability Reporting Quality Index for the same companies of the surveyed managers, that combines several reporting features of disclosure quality. We also consider whether other external factors, such as governance characteristics, social influence, and sustainable education, affect managers' intention to engage in Sustainability Reporting. The results reveal that our model, along with sustainable education and social influence explain more than 56% of the intention to engage in Sustainability Reporting. This indicates that the latter latent variable is well predicted, confirming the relevance of managers' beliefs in driving quality Sustainability Reporting practices. Our findings may specifically help business managers and decision-makers to identify the factors that are likely to influence sustainability reporting in Italy and Spain and contribute to develop efficient sustainable reporting strategies by decision-makers. [ABSTRACT FROM AUTHOR]

Purpose: Governments around the world have shown poor capabilities in responding effectively to the COVID-19 health emergency outbreaks. After the declaration of COVID-19 as an international pandemic by the World Health Organization on January 31, 2020, three countries experienced the greatest initial impact in Europe. Sequentially Italy, Spain and the United Kingdom (UK) were hit by the highest numbers of contagion and death in the first few months in Europe. The aim of this paper is to assess how information channels and sources influenced the public's evaluation of the three government's communication response strategies. Design/methodology/approach: An online survey was conducted between March 14 and April 14, 2020, during the first wave of lockdowns and declarations of States of Emergency in the three countries. Findings: Findings show particularities for the different countries, but also similarities in response and reactions of the public in the three scenarios. The response strategy of the UK Government was the most untrusted and criticized by citizens. In contrast, the Italian and Spanish Governments, which both chose to respond with the severest restrictions, attracted more support from citizens, especially in Italy, which was the first to close borders and impose lockdowns for the population. Research limitations/implications: Despite the national differences in the preference of information channels and sources, overall, an empirical relationship between government communication assessment and media use were found in all the scenarios. Practical implications: This empirical study has theoretical and practical implications. Theoretically, findings will add evidence of implications of the Channel Complementary Theory to the field of risk, crisis and emergency communication. The results also provide insights for communication practitioners in the public sector on how forms of information and trust in sources influence the public's assessment of authorities' communication. Originality/value: Implications for theory and empirical research about communication during a health pandemic are identified and discussed. Highlights: Citizens engage at a high level and synchronize their use of multiple media and platforms in all the three national scenarios. Stronger criticism is provided by online media, especially social media and online press in the different national contexts. Results corroborate that factors related to media choice need to be operationalized for risk and crisis communication research. When public health depends on people understanding the actions they need to take, the possibility of disobedience is highly dependent on trust. Compared with Spain and the United Kingdom (UK), trust in government institutions in Italy was stronger and could be explained by the higher use of owned media for information-seeking. [ABSTRACT FROM AUTHOR]

749 Amidst the COVID-19 outbreak, Italy as well as a number of other European states, including Austria, Germany and Spain, enacted emergency legislation suspending subordination of shareholders and intragroup loans in order to help companies stay afloat. While this measure was clearly prompted by extraordinary circumstances, it should be noted, however, that unlike jurisdictions which adopt automatic subordination, such as Germany and Spain, or where subordination is also based on quantitative criteria, such as Austria, subordination in Italy is based on flexible standards that may not strictly call for an emergency suspension. The COVID-19-related suspension of subordination provides the momentum for reassessing the scope of application of the subordination of shareholder and intragroup loans under Italian law. Although substantially unexplored in the international legal literature, subordination was introduced in Italy in 2003 and has now been applied for nearly twenty years. The system is quite sophisticated and also recognizes a variety of restructuring exemptions allowing priority to the loans. This paper examines subordination of shareholder and intragroup loans under Italian law, seeking to establish a workable construction of the standards of the excessive imbalance between debt and equity and of the reasonableness of a capital contribution on which the application of the remedy is predicated. Building also on relevant economic studies, the paper argues that the Italian subordination system has the potential to distinguish between desirable and undesirable shareholder and intragroup loans based on whether the loan is intended to finance positive net present value projects, restricting the latter while not deterring the former, so as to guarantee the goal of increasing the expected total value of the company and producing better satisfaction of creditors' claims. 750 [ABSTRACT FROM AUTHOR]

The Global financial crisis of 2008-2009 severely impacted the developed economies of the world. It occurred at a time when most countries had started gaining economic growth, stability, and vibrance. Each country experienced a jolt to its economy, causing financial fragility, shocks, tragedy, and struggle. Attempts have been made to understand the root causes, economic instability, and the lessons learned from the great recession. Given the current situation of the COVID-19 pandemic, this research paper seeks to examine the global recession, its effect on the economy and finances. Our research is based on the qualitative analysis of comparing the impact of the global financial crisis and strategic recovery recession plans of the top five GDP countries in the European Unionparticularly Germany, the UK, France, Spain, and Italy to draw some similarities between a recession and COVID-19 pandemic in terms of the economy. The findings indicate that the great recession had a devastating impact on the entire economy, and the world can learn valuable lessons. It notes that out of the selected five EU countries, Germany was the first to recover and bounce back by 2011, but Italy and Spain were severely hit and took longer to recover only partially. The recession recovery strategies demonstrate some similarities in economic and employment measures and differences concerning tax reforms and financial support packages initiated by all five countries. There needs to be a mechanism in which each country must prepare for untimely recessions. Thus, a developmental model has been created to enable countries to be more prepared when faced with recessions in the future years. [ABSTRACT FROM AUTHOR]