1. Multiple Sclerosis Therapy Consensus Group (MSTCG): position statement on disease-modifying therapies for multiple sclerosis (white paper)
- Author
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Christoph Kleinschnitz, Boris Kallmann, Frank Weber, Florian Deisenhammer, Hayrettin Tumani, Michael Platten, Luisa Klotz, Fedor Heidenreich, Karl Baum, Uwe K. Zettl, Tjalf Ziemssen, Ralf A. Linker, H. Wiendl, Stephan Schmidt, Sven G. Meuth, Christian Enzinger, Stefan Bittner, Elisabeth Fertl, Verena I. Leussink, Volker Limmroth, Renaud Du Pasquier, Franziska Di Pauli, Michael Guger, Martin Berghoff, Uta Meyding-Lamadé, Achim Gass, Adam Czaplinski, Hans-Peter Hartung, Peter Rieckmann, Norbert Goebels, Klaus Gehring, Aiden Haghikia, Olaf Hoffmann, Mathias Mäurer, Tobias Derfuss, Frauke Zipp, Thomas Berger, Fritz Leutmezer, Martin S. Weber, Orhan Aktas, Ralf Gold, Jan D. Lünemann, Andreas Lutterotti, Andrew T. Chan, and Claudio Gobbi
- Subjects
Position statement ,medicine.medical_specialty ,treatment recommendation ,Medizin ,610 Medicine & health ,Review ,Disease ,multiple sclerosis ,03 medical and health sciences ,0302 clinical medicine ,White paper ,Neuronal damage ,medicine ,030212 general & internal medicine ,RC346-429 ,Intensive care medicine ,Pharmacology ,business.industry ,Multiple sclerosis ,Disease mechanisms ,Guideline ,medicine.disease ,disease-modifying therapy ,3. Good health ,Group treatment ,Neurology ,Neurology. Diseases of the nervous system ,Neurology (clinical) ,business ,guideline ,030217 neurology & neurosurgery - Abstract
Multiple sclerosis is a complex, autoimmune-mediated disease of the central nervous system characterized by inflammatory demyelination and axonal/neuronal damage. The approval of various disease-modifying therapies and our increased understanding of disease mechanisms and evolution in recent years have significantly changed the prognosis and course of the disease. This update of the Multiple Sclerosis Therapy Consensus Group treatment recommendation focuses on the most important recommendations for disease-modifying therapies of multiple sclerosis in 2021. Our recommendations are based on current scientific evidence and apply to those medications approved in wide parts of Europe, particularly German-speaking countries (Germany, Austria, and Switzerland). in press, CA extern
- Published
- 2021