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COVID-19 first appeared in December of 2019 in Wuhan, China. Since then, it has become a global pandemic. A robust and scalable diagnostics strategy is crucial for containing and monitoring the pandemic. RT-PCR is a known, reliable method for COVID-19 diagnostics, which can differentiate between SARS-CoV-2 and other viruses. However, PCR is location-dependent, time-consuming, and relatively expensive. Thus, there is a need for a more flexible method, which may be produced in an off-the-shelf format and distributed more widely. Paper-based immunoassays can fulfill this function. Here, we present the first steps toward a paper-based test, which can differentiate between different spike proteins of various coronaviruses, SARS-CoV-1, SARS-CoV-2, and CoV-HKU1, with negligible cross-reactivity for HCoV-OC43 and HCoV-229E in a single assay, which takes less than 30 min. Furthermore, our test can distinguish between fractions of the same spike protein. This is done by an altered assay design with four test line locations where each antigen builds a unique, identifiable binding pattern. The effect of several factors, such as running media, immunoprobe concentration, and antigen interference, is considered. We find that running media has a significant effect on the final binding pattern where human saliva provides results while human serum leads to the lowest signal quality.

During attempts to prevent and control the COVID-19 pandemic in China, higher education programs shifted their traditional educational models to online models. This paper aimed to explore how Chinese universities organized online teaching and learning during the pandemic. It investigated the factors affecting the implementation of online teaching and provided policy recommendations for improving the quality of education in the post-pandemic period. The primary data for this study came from in-depth interviews with nine students and five teaching and administrative staff at eight major universities in mainland China. Literature was obtained in both English and Chinese from January 2020 to September 2021. Peer-reviewed journals, policy reports, and university documents regarding online education in Chinese universities were reviewed, and their challenges and countermeasures were investigated. The paper found that the implementation of online education was affected by various sources, including technologies, teachers' teaching skills, network information literacy, and students' learning motivations and self-directed learning skills. Based on the insiders' views, the paper suggested that to promote the quality of online education in the post-COVID-19 pandemic, higher education institutes and programs could develop their infrastructure construction, improve teachers' quality of teaching, and focus on students' learning motivations.

The 2022 anti–zero Covid White Paper protests that erupted in China and its diaspora demonstrated the intertwinement of politics and performance in contemporary China. The symbolic dimensions of blank sheets of A4 paper and other performative tactics used in these demonstrations exemplify the shifting roles of performance art in the field of contemporary Chinese art. [ABSTRACT FROM AUTHOR]

Aims: To determine the associations between COVID-19 school closures and school readiness skills for Chinese kindergarteners., Design: We utilized the natural experimental condition created by local COVID-19 outbreaks in 2022 (Study 1) to compare school readiness skills of children whose kindergartens were closed for 5 months (Group 1) with children whose kindergartens stayed open (Group 2). We further compared the school readiness skills of one pre-COVID-19 cohort (Cohort 2019) with one COVID-19 cohort (Cohort 2021) from a fifth kindergarten (Study 2)., Samples: For Study 1, Group 1 included 445 children and Group 2 included 584 children aged 4-6 years. For Study 2, Cohort 2019 included 156 children and Cohort 2021 included 228 children aged 3-6 years., Measures: For both studies, survey data on four school readiness skills were collected from parents. Additionally, Study 1 collected parental locus of control data from parents., Results: Controlling for covariates, Study 1 revealed that Group 1 and Group 2 did not differ in terms of language and emergent literacy or approaches to learning. However, Group 1 scored lower than Group 2 on health and well-being and arts and imagination. Study 2 revealed that Cohort 2021 scored higher than Cohort 2019 on language and emergent literacy but lower on the other three skills., Conclusions: The associations of COVID-19 school closures with Chinese children's school readiness skills were not uniform, with a positive relation with language and emergent literacy and negative associations with health and well-being, approaches to learning, as well as arts and imagination., (© 2024 British Psychological Society.)

This paper describes a scoping review of China's academic resource databases, relevant official websites, news reports and public accounts spanning a period from the end of 2019 to the end of 2022, to investigate the challenges in scientific integrity and ethical soundness of research conducted during and immediately after the COVID-19 pandemic in China. By conducting the scoping review with keywords related to the research questions in Chinese, relevant data were extracted and classified into four categories: challenges in research, challenges in ethics review, challenges in publishing academic work, and research ethics guidelines during and after the pandemic. The paper points out that problematic studies and findings increased with the escalation in medical research projects during the pandemic in China. The situation faced by researchers was more difficult than before the pandemic. The mode of informed consent, and ethics review and oversight systems also underwent changes. In addition, Traditional Chinese Medicine as an alternative medical treatment for COVID-19, attracted attention from the research community and became a topic of discussion. We conclude that the various challenges and concerns identified indicate a need for a proper and timely response system be formulated in preparation for possible future occurrences of new pandemics or other critical situations.

Unlike in developed countries, most public toilets in China do not provide toilet paper onsite and users must bring their toilet paper. Moreover, an open waste bin is placed in each user's cubicle to collect used toilet paper and tissues. Such practices, which are common in East Asia and central America, have induced a dilemma of toilet paper disposal because some municipalities have removed waste bins from public toilets to prevent virus transmission by fecal matter. As a consequence, users were forced to flush down their used toilet paper and tissues. Yet, it is unknown whether standard toilet paper can be flushed easily without causing issues in sewer operations. Here, we surveyed the conditions of toilets in university campus and other public facilities in different regions across China. We also evaluated the disintegration characteristics of toilet paper products both by conducting online surveys and by physical disintegration experiments. We found that only 15% of toilets provided toilet paper, while open waste bins occurred at nearly all sites. Further, our survey indicated that 82% of toilet paper products sold in China did not give any indication on their flushability, whereas 77% of US products did. Disintegration results showed that none of the five popular, best-selling toilet paper products passed the flushability standard. We propose strategies to solve the current toilet paper dilemma in developing communities. [ABSTRACT FROM AUTHOR]

At the end of 2022, a huge tide of SARS-CoV-2 infection mainly Omicron BA.4/5 developed in China. Multiple myeloma (MM) patients suffered cancer deterioration and mortality from COVID-19, yet profound analyses of Omicron variants-induced immunity function are scarce. We presented a longitudinal study in 218 MM patients and 73 healthy controls (HCs), reporting the prognostic factors and dynamic humoral and cellular immune responses. Neutralizing antibody and interferon γ ELISpot assay of SARS-CoV-2 was tested at three time points: 2-4, 8-10, and 14-16 weeks after infections. Our data showed older age, active MM, relapsed/refractory MM (R/RMM), immunotherapy, comorbidity, and non-vaccination were risk factors associated with hospitalization. Severe humoral immunity impairment within 2-4 weeks was especially seen in patients with unvaccinated, older age, immunotherapy, R/RMM and comorbidities, while T-cell response was relatively intact. Although antibodies of Omicron variants reached positive levels in MM patients at 8-10 weeks, half lost effective antibody protection at 14-16 weeks. However, most seronegative patients (76.2% at 2-4 weeks, 83.3% at 8-10 weeks) could develop effective T-cell response. Notably, the inactivated wild-type vaccinated patients exhibited weaker humoral and cellular immunity only at 2-4 weeks, escalating to similar levels as those in HCs later. Our findings indicate impairment of humoral immunity at acute-phase after infection is the major factor correlated with hospitalization. One-month suspension of immune therapy is suggested to prevent serious infection. These results confirm the value of inactivated vaccine, but indicate the need for additional booster at 14-16 weeks after infection for high-risk MM population., (© 2024 UICC.)

The relationship between water, energy, food, and the environment has piqued the interest of the global community due to the critical interdependence of these resources for long-term development. This article investigates research within the field of the quadruple nexus. Data from Scopus documents, with the keywords "water, energy, food, and environment" from 2011 to 2022, were processed and analyzed. Further research revealed that scientific exploration of the water-energy-food-environment relationship is rapidly expanding. The Scopus database was used to extract information about countries, institutions, highly cited publications, keywords, hot topics, and future research trends for this study. Additionally, the VOSviewer bibliometric software was employed to evaluate the scientific citations in this article. The results indicated that the USA, compared to other nations, publishes a larger quantity of articles in this field. Recently, China, India, and Middle Eastern countries have garnered significant attention and have been extensively researched. The Philippines, Finland, and Iran have also emerged among the top nations publishing recent articles on the water-energy-food-environment nexus (WEFEN). This article attempts to study the bibliography on the WEFEN connection, identify popular topics, and discern the fields of future studies in this discussion. Furthermore, it investigates the effects of economic and social factors as well as the impact of the COVID-19 pandemic on this quadruple nexus., (© 2023. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.)

Building on a theoretical model of decision-making under risk and uncertainty, this paper examines how Chinese college students made decisions about international moblity or immobility during the COVID-19 pandemic. The paper finds that among the 118 interviewees, most continued to choose to study abroad, whilst some gave up after getting offers from prestigious Western universities. We further analysed the divergent patterns of two choices which can be explained by resilience to risks and uncertainties and lack of thereof. For those who have given up studying abroad, the symbolic capital and labor market advantages brought by degrees (especially master degrees) from Western universities have become uncertain and offset by the risk of the epidemic. These findings suggest that, in addition to safety, college students will prefer certainty more than before when choosing whether to go abroad and the study abroad landscape may change based on this mindset.

The enhancement of regional comprehensive development ability is significantly impacted by the study on the implementation effect of regional integration strategies. The integration strategy's impact on urban development during COVID-19 in the Yangtze River Delta(YRD) is unclear. According to prior industrial transfer theory, Hefei, Anhui's capital, is difficult to transfer industries, and other YRD cities push industry integration in Anhui. This study employs the theory of economic and land resource use to examine the resilience of the industrial economy during an epidemic by using industrial land as a representation of industrial economic development. The three cities in Anhui-Wuhu, Maanshan, and Chuzhou (Wu-ma-Chu) were selected as the research area. The study employed the UNet deep learning method to detect the land use types in Wu-ma-Chu. The land transfer matrix and the standard deviation ellipse were utilised to research the alterations in industrial land use and the spatial distribution of industrial output value, respectively. The results showed that the industrial land in Machu continued to grow during the outbreak, highlighting the resilience of the region's industrial economy. During 2019-2022, the elliptical ring of industrial output value is distributed in Nanjing, revealing the radiating role of Nanjing in integrating into the integration of the YRD. This confirms China's YRD integration strategy, strengthens regional economic resilience, and encourages coordinated regional economic development., (© 2024. The Author(s).)

Although previous research has reached agreement on the significant impact of particulate matter (PM 2.5 ) on respiratory infectious diseases, PM 2.5 acts as an aggregation of miscellaneous pollutants and the individual effect of each component has not been examined. Here, we investigate the effects of PM 2.5 components, including black carbon (BC), organic carbon (OC), sulfate ion (SO 4 ), dust, and sea salt (SS), on the morbidity and mortality of the recent respiratory disease, i.e. COVID-19. The daily data of 236 countries and provinces/states (e.g., in the United States and China) worldwide during 2020-2022 are utilized. To derive the pollutant-specific causal effects, optimal instrumental variables for each pollutant are selected from a large set of atmospheric variables. We find that one µg/m 3 increase in OC increases the number of cases and death by about 3% to 6% from the mean worldwide during a lag of one day up to three days. Our findings remain consistent and robust when we change control variables such as the flight index and weather proxies, and also when applying a sine transformation to the positivity and death rate. When analyzing health effects among different areas, we find stronger impact in China, for its higher local OC concentration, as opposed to the impact in the United States. Health benefits from PM 2.5 pollution reduction are comparatively high for developed regions, yet decreases in cases and deaths number are rather overt in less developing regions. Our research provides inspiration and reference for dealing with other respiratory diseases in the post-pandemic era., (© 2024. The Author(s), under exclusive licence to Springer Nature B.V.)

Aim: Being front-line healthcare professionals is associated with possible severe information anxiety during the COVID-19 pandemic. Investigating signs of information anxiety is the first and key step of its targeted medical intervention. This study aims to explore the signs of front-line healthcare professionals' information anxiety during the COVID-19 pandemic., Design: This study is qualitative research. Grounded theory was used to classify information anxiety signs of front-line healthcare professionals., Methods: Twenty-four front-line healthcare professionals from a general hospital with over 5000 beds in Wuhan were recruited to participate in semi-structured interviews. According to the frequency and frequency variation of signs appearing in interviews, the trends of signs during the virus encounter, lockdown, flattening and second wave were compared. Based on the interviews, those signs that were conceptually related to each other were extracted to construct a conceptual model., Results: Psychological signs (emotion, worry, doubt, caution, hope), physical signs (insomnia, inattention, memory loss, appetite decreased) and behavioural signs (panic buying of goods, be at a loss, pay attention to relevant information, change habits) could be generalized from 13 subcategories of information anxiety signs. Psychological signs were the most in every period of the pandemic. Furthermore, psychological signs decreased significantly during lockdown, while behavioural and physical signs increased. Finally, severe psychological and behavioural signs were associated with physical signs., (© 2024 The Author(s). Nursing Open published by John Wiley & Sons Ltd.)

Purpose: The global COVID-19 epidemic has posed significant challenges to the development of innovation and entrepreneurship education in Chinese and foreign universities, and the application of artificial intelligence generated content (AIGC) technology has presented both opportunities and challenges to its development. The purpose of this study is to summarize advanced experiences and models of new engineering innovation and entrepreneurship education development in Chinese and foreign universities, as well as to analyze the influencing factors. Taking the sustainable development goals (SDGs) into account, this study qualitatively proposes enhancement paths and improvement suggestions based on the application of AIGC technology, providing a reference for promoting the sustainable development (SD) of innovation and entrepreneurship education in Chinese universities. Design/methodology/approach: By using the qualitative comparative analysis (QCA), this paper studies the interaction mechanism between the influencing factors of innovation and entrepreneurship in universities under the background of SDGs. This paper selects 12 representative universities with different cultures and strengths. Meanwhile, this paper analyzes the content of 2,535 publications on innovation and entrepreneurship education and summarizes seven influencing factors as comparison criteria. Then, this paper codes, summarizes and uses configuration to assess the primary factors influencing the development of innovation and entrepreneurship in colleges and universities at home and abroad. Findings: On the quality of new engineering innovation and entrepreneurship education, comprehensive, diverse influencing factors and upgrading paths are obtained. Furthermore, this research proposes that the SD of innovation and entrepreneurship education in universities should make effective use of "AI plus education" and actively construct practical and teaching platforms. Meanwhile, the ChatGPT is being used to strengthen the innovation and entrepreneurship curricular system and talent training mode. The research also makes recommendations for improving teachers' ability to acquire intelligent tools and promotes three-way teaching modalities of "teacher-AI-student" by taking into account the influence of various aspects. Originality/value: This research uses the QCA research method, which analyzes not only influencing factors on the SD of innovation and entrepreneurship education but also explores the interaction mechanisms among factors. Furthermore, the research incorporates SDGs and AIGC technology application scenarios into the field of domestic innovation and entrepreneurship education, which will be helpful in SDGs of innovation and entrepreneurship education on both theoretical and practical levels.

In an attempt of curricula improvement, many seek to create new approaches that would help develop the necessary knowledge within a shorter period of time. The primary purpose of this paper is to investigate the role of interactive piano teaching in distance learning. The paper suggests new learning approaches to interactive piano instruction. The training programme is based on interactive groups, the Flowkey application, technical and psychological aspects, improvisation, changing role positions, and the development of self-control. The programme results showed that 83% out of 120 students demonstrated a high level of knowledge, and only 2% showed a low level, which was explained by absenteeism. 28% out of 120 students learned to recognise melodies, 27% improved rhythm and tempo, 25% gained two-handed playing skills, and 20% out of 120 students developed improvisation skills. The results have scientific value for researchers engaged in studying various training programmes.

Transnational routes such as direct-entry have become a more attractive option for Chinese students, due to the pandemic-imposed travel restrictions in China. The rise of Chinese direct-entry students can potentially lead to a significant increase in demand for academic and non-academic support not only after their arrival, but also before their departure from China. By applying Schlossberg's transition theory, this paper seeks to develop a good understanding of the academic and social belonging of Chinese direct-entry students in the UK through re-analysing the portraits (written narratives) of a previous research project. The findings indicate that these students were feeling disconnected from the academic and social communities. The factors affecting their sense of belonging are described using the 4S framework, namely self, strategies, situation and support. The paper ends with recommendations to key university stakeholders on how the partner institutions in China and the UK can help enhance a sense of academic and social belongingness of Chinese direct-entry students.

Higher education informatization (HEI) is an interdisciplinary field that examines the use and integration of information and communication technologies (ICTs) in higher education. This paper provides a bibliometric and visual analysis of the research trends, patterns, and topics in this field. Using the Web of Science database, the authors selected and analyzed 199 SCI and SSCI papers on HEI published from 2000 to 2023 by VOSviewer and CiteSpace software. The results indicate that the publication volume of HEI research has grown significantly in recent years. The author network shows the collaboration and contribution of different researchers and institutions, while the journal network reveals the multidisciplinary nature and scope of the field. The keyword network and the burst keyword analysis identify the main research themes and the emerging hot topics in HEI. The co-citation network of sources illustrates the theoretical and methodological foundations and influences of the field. The paper concludes with some implications and suggestions for future HEI research.

Research excellence is one of the key missions of universities and an important engine for socio-economic development. However, the outbreak of COVID-19 has affected academic research in many ways. This study examines the impact of the COVID-19 pandemic on the research performance of science and engineering faculty members in China's top research universities. It is found that the pandemic caused a decline in the numbers and quality of published articles, and the effects persisted over time. The negative effect of the pandemic on research excellence was more pronounced in the older faculty groups and departments of science. In addition, the pandemic has harmed international research collaborations among academics, which is likely to obstruct research excellence in the long run. In the end, this paper proposes several policy recommendations to reinvigorate universities' capacity for research innovation in the post-pandemic era.

This paper addresses the substantial role of clan loyalty in promoting COVID-19 diffusion in China. Using a city-date panel dataset of observations from 183 cities (prefecture-level and above) in the period of the special long holiday of Chinese New Year in 2020 (January 24-March 1), we find that regions with higher clan loyalty have more COVID-19 cases than regions with lower clan loyalty. A one standard deviation increase in clan loyalty is associated with an 8.1% increase in COVID-19 cases. We further document that clan loyalty drives COVID-19 cases by promoting mass gatherings, exploiting a staggered difference-in-differences (DID) regression based on city community-management policy shocks. Our paper provides novel evidence of one negative public health consequence of clan loyalty, namely, its aggravation of COVID-19 cases., (© 2023 John Wiley & Sons Ltd.)

Aim: The paper presents a bibliometric analysisis of high-cited papers (HCPs) on Covid-19 published during 2019-2021. The study provides evidence on current research trends in the subject, identifies influential countries, organizations, research papers and journals on Covid-19 research. The study evaluates publication and citation performance of highly-cited papers and maps network interactions amongst the key global players using VOSviewer software. Materials and Methods: The data for the study was sourced from Web of Science for the period 2019-2021. Results: The USA, China and the UK dominate global Covid-19 research in terms of research productivity. In terms of citation performance China leads the tally with the USA at the second position. The USA, China and the UK account for a 88% share of total HCPs in the subject. The study identified top eleven centers of excellence based on the criteria of most productivity as well as most-cited organizations. New England Journal of Medicine, Lancet, JAMA - Journal of the American Medical Association, Science and Nature are the most favoured journals for publishing HCPs. The relationship networks of most productive countries, organizations, and keywords are also given in the paper. [ABSTRACT FROM AUTHOR]

The mental health problems caused by COVID-19 pandemic to every person and every group cannot be ignored, especially for college students, who are the main force of the society. Few studies explore the mechanism of action between college students' epidemic stress perception and life satisfaction in China. The study aims to understand the association between the epidemic stress perception of COVID-19 on life satisfaction, and examines the effect of coping flexibility and perceived social support in China. We investigated 597 college students by questionnaire and found college students' epidemic stress perception of COVID-19 was significantly negatively associated with life satisfaction; coping flexibility partially mediated the relationship between college students' epidemic stress perception of COVID-19 and their life satisfaction; perceived social support moderated role in the first half of the mediating pathway. Practical strategies to improve college students' life satisfaction were discussed in the paper.

Purpose: In the domain of shadow education (private supplementary tutoring), Denmark and China may be placed at opposite ends of a spectrum. Denmark has a recently emerged, small, and high-cost sector that mostly serves low achievers, while China has a more industrialized sector with a long history and economies of scale. The paper juxtaposes the two to shed light on each. Design/Approach/Methods: The article is a personal narrative of the author's research experiences. She grew up and had initial education in China before moving to the Nordic realm for 2 years. This provided a set of initial lenses, which were subsequently deployed in research partnership from her current base in China with colleagues in Denmark. Findings: The juxtaposition raises questions that might otherwise not have been asked and provides insights that might otherwise not have been gained. Danish families hesitate to use shadow education for advantages in the egalitarian society, in contrast to Chinese patterns that stress competition and achievement. These facets have implications for the modes of shadow education and even the names of tutorial companies. Originality/Value: The paper has a methodological value in addition to its substantive insights on the trajectories of shadow education in the two countries.

This paper explores a possible future of postdigital education in 2050 using the means of social science fiction. The first part of the paper introduces the shift from 20th century primacy of physics to 21st century primacy of biology with an accent to new postdigital--biodigital reconfigurations and challenges in and after the COVID-19 pandemic. The second part of the paper presents a fictional speech at the graduation ceremony of a fictional military academy in a fictional East Asian country in 2050. This fictional world is marked by global warfare and militarization, and addressed graduates are the first generation of artificially evolved graduates in human history. The third part of the paper interprets the fictional narrative, contextualizes it into educational challenges of today, and argues for a dialogical, humanistic conception of new postdigital education in a biotech future.

This paper draws attention to the current and possible effects of COVID-19 on the mobility trajectories of mainland Chinese students studying in Asia. By drawing on 35 biographical interviews, this paper focuses on their decision to study in Asian countries and regions. Particularly, it calls for more attention to Asia in global student mobilities and discusses whether COVID-19 has changed the position of Asia in the global landscape of student mobility. Results show that even if COVID-19 provides an opportunity for Asian universities to embrace more international students, Asia still lacks the capability to attract great numbers of them. Finally, the study argues that college students' choice of mobility destinations is shaped by their perception of the central-periphery structure of higher education, which is hard to be shaken by the pandemic.

The impact of COVID‐19 has underlined the need for reliable information to guide clinical practice and policy. This urgency has to be balanced against disruption to journal handling capacity and the continued need to ensure scientific rigour. We examined the reporting quality of highly disseminated COVID‐19 research papers using a bibliometric analysis examining reporting quality and risk of bias (RoB) amongst 250 top scoring Altmetric Attention Score (AAS) COVID‐19 research papers between January and April 2020. Method‐specific RoB tools were used to assess quality. After exclusions, 84 studies from 44 journals were included. Forty‐three (51%) were case series/studies, and only one was an randomized controlled trial. Most authors were from institutions based in China (n = 44, 52%). The median AAS and impact factor was 2015 (interquartile range [IQR] 1,105–4,051.5) and 12.8 (IQR 5–44.2) respectively. Nine studies (11%) utilized a formal reporting framework, 62 (74%) included a funding statement, and 41 (49%) were at high RoB. This review of the most widely disseminated COVID‐19 studies highlights a preponderance of low‐quality case series with few research papers adhering to good standards of reporting. It emphasizes the need for cautious interpretation of research and the increasingly vital responsibility that journals have in ensuring high‐quality publications. [ABSTRACT FROM AUTHOR]

Coronavirus disease 2019 (COVID-19) first emerged in China in November 2019. Most governments have responded to the COVID-19 pandemic by imposing a lockdown. Some evidence suggests that a period of isolation might have led to a spike in alcohol misuse, and in the case of patients with alcohol use disorder (AUD), social isolation can favour lapse and relapse. The aim of our position paper is to provide specialists in the alcohol addiction field, in psychopharmacology, gastroenterology and in internal medicine, with appropriate tools to better manage patients with AUD and COVID-19,considering some important topics: (a) the susceptibility of AUD patients to infection; (b) the pharmacological interaction between medications used to treat AUD and to treat COVID-19; (c) the reorganization of the Centre for Alcohol Addiction Treatment for the management of AUD patients in the COVID-19 era (group activities, telemedicine, outpatients treatment, alcohol-related liver disease and liver transplantation, collecting samples); (d) AUD and SARS-CoV-2 vaccination. Telemedicine/telehealth will undoubtedly be useful/practical tools even though it remains at an elementary level; the contribution of the family and of caregivers in the management of AUD patients will play a significant role; the multidisciplinary intervention involving experts in the treatment of AUD with specialists in the treatment of COVID-19 disease will need implementation. Thus, the COVID-19 pandemic is rapidly leading addiction specialists towards a new governance scenario of AUD, which necessarily needs an in-depth reconsideration, focusing attention on a safe approach in combination with the efficacy of treatment. [ABSTRACT FROM AUTHOR]

Using a monthly data between 2008 and 2019, this study investigated how the development of the Internet technologies has shaped the consumer consumption pattern of different types of paper products in China during this period. In detail, this study covers four major types of paper products in the Chinese market: newsprint, printing paper, household paper, and packaging paper. The developments of Internet technologies were decomposed into two aspects: the communication technology (CT) and the software platform technology (PT). Granger causality analysis was employed to determine whether the consumption pattern of paper products was affected by the development of the Internet. Furthermore, impulse-response analyses were utilized to measure how the consumption pattern of each paper product was shaped by the development of each aspect of Internet technologies, i.e., CT or PT. The empirical results suggested that the Internet developments are causing the consumption patterns shifts of all four paper products. Specifically, the consumptions of newsprint and printing paper were driven by both CT and PT. However, the consumptions of packaging paper and household paper were driven by the PT only. Compared to the development of CT, we found that the quick evolution of PT plays a more significant role in shifting people's consumption of paper products in China. The empirical results revealed by this study could provide valuable economics and policy implications to both academia and relevant industries. • Internet development has shifted the paper products consumption pattern in China. • Development of internet boosted the demand for printing paper and household paper. • Development of internet suppressed the demand for newsprint. • The effects of internet technological development are separated into two aspects. • Emerging Internet platforms shifted the consumption of paper products efficiently. [ABSTRACT FROM AUTHOR]

Background: Many patients with Covid-19 have underlying cardiovascular disease or develop acute cardiac injury during the course of the illness. Adequate understanding of the interplay between Covid-19 and Cardiovascular disease is required for optimum management of these patients. The study analyzed and evaluated the global publication output on "Covid-19 and Heart Diseases" to find out the current trends and present status of research, by identifing important countries, organizations, authors and journals and important topics and keywords from the global publications, using bibliometric methods. Methods: Relevant published literature from December 2019 to August 2021 were identified and analyzed on the topic "Covid-19 and Heart Diseases" using a well-defined search strategy in Scopus database. A list of keywords were identified for Covid-19 ("Covid 19" or "2019 novel Coronavirus" or "Coronavirus 2019" or "Coronavirus disease 2019" or "2019-novel CoV" OR "2019 ncov" or "Covid 2019" or "Covid19" or "Corona virus 2019" or "ncov-2019" or "ncov2019" or "nCoV 2019" or "2019-ncov" or "covid-19" or "Severe acute respiratory syndrome coronavirus 2" or "SARS-CoV-2") and Heart Diseases (cardi* or arrhythmia or myocardial* or heart*) and these keywords are used for search in "Keywords" and Title" tags of Scopus database, yielding 5298 records. Results: A total of 5298 relevant publications indexed in Scopus database were obtained on "Covid-19 and Heart Disease", which received 62459 citations, averaging 11.79 citations per paper. The total publications witnessed the participation of 123 countries, with USA, Italy, U.K. and China leading in global publication productivity (with 1757, 707, 551 and 413 papers) and China (35.31 and 2.99), France (23.01 and 1.95), Germany (23.0 and 1.95) and Italy (20.43 and 1.73) leading in citation impact per publication and relative citation index. The 1761 organizations and 2499 authors participated in these 5298 publications. Harvard Medical School, USA, Brigham and Women's Hospital, USA and Massachsetts General Hospital leads in publications productivity (with 178, 92 and 92 publications each) and New York Presbyterian Hospital, USA (121.53 and 10.31), Tongji Medical College, China (65.65 and 5.57) and Huazhong University of Science and Technology, China (65.41 and 5.55) leads in citations impact per paper and relative citation index. M. Metra, A. Harky and M.K. Chung leads in publications productivity (with 23, 22 and 153 papers each) and G.Y.H. Lip (U.K.)(114.67 and 9.73), A.J. Kirtane (USA)(109.67 and 9.3) and M. Metra (Italy)(87.04 and 7.38) leads in citations impact per publication and relative citation index. European Heart Journal, Circulation and Stroke leads in publication productivity (with 85, 81 and 73 publications) and JAMA Cardiology (154.23), Journal of the American College of Cardiology (54.99) and Circulation (43.54) leads in citation impact per paper. Major keywords appearing along with "Covid-19 and "Heart Diseases" in co-occurnces were "Cardiovascular Disease" (1176), "Heart Failure" (802), "Hypertension" (664), "Cerebrovascular Accidents" (659), "Stroke" (608), "Mycarditis" (511), "Heart Arrhytthrmia"(464), etc. Conclusion: The study presents the current trends and status of research in the field and indicate the important keywords where research is focused in global literature on cardiovascular manifestations in Covid-19 patients. Such a analysis tmay be useful to the research community and decision-makers to prioritize research needs and identify leading Covid-19 researchers, countries, institutes and authors. [ABSTRACT FROM AUTHOR]

COVID-19 has transformed higher education learning and teaching practices globally. Tertiary students, internationally face both opportunities and challenges in learning and adapting to this paradigm shift in the delivery of education. It remains unclear how students in international contexts are responding to these changes in digital learning during and post-COVID-19. This paper aims to compare student perceptions of digital competence, confidence, and resilience in present times using data from surveys of tertiary students from Australia, Cambodia, China, India, and Malaysia. There are disparities not only in the teaching and learning pedagogies amongst these countries but also in the levels of technological advancement, infrastructure support, and pace of digital innovation in the delivery of courses. These differences have put in focus students' both digital competencies and resilience as they pursue higher education on various digital learning platforms. Resilience includes the ability to bounce back or adapt from stress (Smith et al., 2008). Digital resilience is students' tech-savviness and preparedness to adapt to different digital environments as they pursue higher education. This paper examines the perceptions of tertiary undergraduate students from these countries in this emerging new digital learning norm. A total of 687 tertiary students from the aforementioned countries participated in a survey to questions related to digital competence, confidence in using and/or adapting to digital innovation, and resilience. Statistically significant attributes are identified to help better understand the challenges these culturally diverse students perceive in digital learning environments. This study will reveal barriers that impact the digital transformation of undergraduate students which can be used to recommend necessary teaching and learning support frameworks to enhance their digital competence and resilience. This will help tertiary institutions better equip all stakeholders in adapting to the new normal of higher education in the future.

The entire education system, from elementary school to higher education, distorted during the lockdown period. The latest 2019 coronavirus disease (COVID-19) is not only recorded in China, but also globally. This research is an account of the online teaching paradigm assumed in the teaching method by most of universities in China and subsequent tests over the course. It looks forward to offering resources rich in knowledge for future academic decision-making in any adversity. The aim of this research paper is to explain the prerequisites for online education and teaching during the COVID-19 pandemic and how to effectively turn formal education into online education through the use of virtual classrooms and other main online instruments in an ever-changing educational setting by leveraging existing educational tools. The paper uses both quantitative and qualitative research approaches to analyses the views of online teachers and students on the learning regime, with specific attention to the online learning regime implementation process. In the midst of the COVID-19 outbreak, the purpose of this article is to provide an in-depth overview of online learning. These activities took place during a time of isolation, including the creation of a link between the process of change management and the online learning process in the education system to tackle current issues of academic interference and, however, the re-establishment of educational practice and debate as a normal system of procedural education.

This rapid systematic review aims to examine emerging evidence on the effects of COVID-19 on educational institutions and assess the prevalence of e-learning changes in the sector. This paper reviews literature on learning, teaching, and assessment approaches adopted since the COVID-19 outbreak, and assesses the impact on the sector, staff, and students, summarizing findings from peer-reviewed articles. It categorizes these into five key themes: (1) digital learning; (2) e-learning challenges; (3) digital transition to emergency virtual assessment (EVA); (4) psychological impact of COVID-19; and (5) creating collaborative cultures. This represents the first systematic review of COVID-19's impact on education, clarifying current themes being investigated. The author suggests that the term 'emergency virtual assessment' (EVA) is now added for future research discussion. Finally, the paper identifies research gaps, including researching the impact on lesser developed countries, the psychological impact of transition, and the important role of leadership and leadership styles during the transition and handling of the pandemic.