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Bioarchaeology lacks a system for recording the morphology of muscle and ligament attachment sites, called entheses, in growing individuals. Such information is useful in investigating factors that affect bone growth and development, including sex, age, puberty, pathology, and activity. This paper presents a standardized recording method for nonadult entheses based on 29 archaeological individuals of archivally known sex and age-at-death, ranging from two to 17 years. This paper (a) assesses the range of osseous changes of 16 entheses in the upper and lower limbs of growing individuals, and (b) presents a scoring method for each enthesis, which is evaluated through inter-and intra-observer comparisons. Nonadult entheses show a wide range of morphological variation. Method reproducibility is established. This method will allow researchers to further investigate factors affecting bone development in nonadult skeletal remains. [ABSTRACT FROM AUTHOR]

The article presents the discussion on revised recommendations for celiac disease (CD) screening and biopsy including consideration of a serology-based diagnostic approach. Topics include expanded section on skin disorders showing continuous glucose monitoring (CGM)-related and insulin pump-related skin issues; and screening for thyroid disease by measurement of TSH, anti-thyroid peroxidase antibodies and anti-thyroglobulin antibodies.

Maturation progresses at different times and at different rates between individuals. Thus, differences in maturity status exist among players in the same chronological age‐based category, especially in U14 players. The purpose of this prospective study was to describe injury burden according to the relative skeletal maturity status in U14 elite academy football players. From 2011 to 2020, injuries and individual exposure (training and match) were prospectively recorded in 183 male U14 players. Skeletal age (SA) was assessed using the Tanner‐Whitehouse 2 method. Relative skeletal maturity status [SA minus chronological age (CA)] was classified as follows: early (SA–CA > 0.5), on‐time (SA–CA ± 0.5), and late (SA–CA < −0.5). Overall and specific injury burden (days lost/1000 h) and rate ratios for comparisons between groups were calculated. Overall injury burden was 2.8 times higher (3.6 times in training) in early maturers compared with late maturers. Growth‐related injuries were the most burdensome injuries in all three groups, but significant differences were not found between groups. Muscle injuries were 4 times more burdensome in early maturers compared with on‐time and late maturers. Besides, joint/ligament injuries were 7 and 12 times less burdensome in late maturers than in on‐time and late maturers, respectively. Significant differences between groups in overall and specific injury burden were not found in matches. Our results showed different injury patterns in U14 early, on‐time, and late maturers. Hence, monitoring maturity seems crucial to detect potential injuries that cause the greatest disruption, and facilitate design of targeted injury prevention programs. [ABSTRACT FROM AUTHOR]

Background: Complete growth measurements are an essential part of pediatric care providing a proxy for a child's overall health. This study describes the frequency of well-child visits, documented growth measurements, and clinic and provider factors associated with measurement. Methods: Retrospective cross-sectional study utilizing electronic medical records (EMRs) from primary care clinics between 2015 and 2017 in Manitoba, Canada. This study assessed the presence of recorded height, weight and head circumference among children (0–24 months) who visited one of 212 providers participating in the Manitoba Primary Care Research Network. Descriptive and multivariable logistic regression analyses assessed clinic, provider, and patient factors associated with children having complete growth measurements. Results: Our sample included 4369 children. The most frequent growth measure recorded was weight (79.2% n = 3460) followed by height (70.8% n = 3093) and head circumference (51.4% n = 2246). 67.5% of children (n = 2947) had at least one complete growth measurement recorded (i.e. weight, height and head circumference) and 13.7% (n = 599) had complete growth measurements at all well-child intervals attended. Pediatricians had 2.7 higher odds of documenting complete growth measures within well-child intervals compared to family physicians (95% CI 1.8–3.8). Additionally, urban located clinics (OR 1.7, 95% CI 1.2–2.5), Canadian trained providers (OR 2.3, 95% CI 1.4–3.7), small practice size (OR 1.6, 95% CI 1.2–2.2) and salaried providers (OR 3.4, 95% CI 2.2–5.2) had higher odds of documented growth measures. Conclusions: Growth measurements are recorded in EMRs but documentation is variable based on clinic and provider factors. Pediatric growth measures at primary care appointments can improve primary prevention and surveillance of child health outcomes. [ABSTRACT FROM AUTHOR]

Injuries are common in elite adolescent athletics, but few studies have addressed risk factors for injury. Growth and maturation are potential risk factors in this population; however, the current body of literature is both inconclusive and considered at high risk of bias. The aim of this study was therefore to examine whether growth rate, maturity status, and maturity tempo are associated with injury risk in an elite sports academy. Anthropometric, skeletal maturity and injury data collected prospectively over four seasons (117 athlete‐seasons) were included in the analyses. Growth rate for stature was associated with greater risk of bone (incidence rate ratio (IRR): 1.5 per one standard deviation increase above the mean; 95% CI: 1.1‐1.9) and growth plate injuries (IRR: 2.1; 1.5‐3.1). Growth rate for leg length was associated with greater overall injury risk (IRR: 1.3; 1.0‐1.7) as well as the risk of bone (IRR: 1.4; 1.0‐1.9) and growth plate injuries (IRR: 2.1; 1.4‐3.0). Athletes with greater skeletal maturity, expressed as skeletal age (IRR: 0.6 per year; 0.5‐0.9) and percentage of predicted mature height (IRR: 0.8 per percent increase; 0.7‐1.0), were less prone to growth plate injuries. Rate of change in skeletal age was associated with an increased risk of bone injuries (IRR: 1.5; 1.0‐2.3). The results of this study suggest that rapid growth in stature and leg length, skeletal maturity status, and maturity tempo represent risk factors for certain injury types in adolescent athletics. [ABSTRACT FROM AUTHOR]

Objectives: Previous studies have demonstrated the need for regionally specific stature estimation formulae due to the geographical specificity of limb proportionality related to the effects of environmental pressures on growth and development. High‐altitude Andean populations have often been neglected in the creation of these formulae. This study uses a hybrid approach to create linear regression formulae for stature estimation and test their accuracy when compared previously published formulae traditionally used in Andean bioarchaeology. Materials and Methods: We studied a sample from a high‐altitude Andean population to create linear regression formulae based on anatomical estimates of stature from the femur, tibia, and calcaneus and compare the newly created formulae with those traditionally employed in Andean bioarchaeology. We also examine the reliability of calcanei in stature estimation by creating and testing regression formulae based on metrics from that element. Results: We include specific formulae accurate to within 1 cm of anatomical stature estimates using femoral, tibial, and calcaneal metrics. These formulae provide estimates that are closer to anatomical stature than those traditionally used in the Andes. ANOVA results were statistically significant for differences between Andean‐derived and Mesoamerican‐derived formulae. Discussion: Although regionally proximate (mid‐altitude) formulae provide estimates approximating population‐specific formulae, those created from geographically distant populations from sites at or near sea‐level are inappropriate in high‐altitude studies. Like some previous studies on stature, we found that the most accurate estimates were based on the tibia rather than the femur and that the calcaneus can be used reliably in stature estimation when no other element is present or measurable. [ABSTRACT FROM AUTHOR]

Abstract: World Health Organization recommends exclusive breastfeeding for infants for the first 6 months of life, followed by introduction of nutritious complementary foods alongside breastfeeding. Breast milk remains a significant source of nourishment in the second half of infancy and beyond; however, it is not clear whether more breast milk is always better. The present study was designed to determine the association between amount of breast milk intake at 9–10 months of age and infant growth and development by 12–18 months of age. The study was nested in a randomized controlled trial conducted in Malawi. Regression analysis was used to determine associations between breast milk intake and growth and development. Mean (SD) breast milk intake at 9–10 months of age was 752 (244) g/day. Mean (SD) length‐for‐age z‐score at 12 months and change in length‐for‐age z‐score between 12 and 18 months were −1.69 (1.0) and −0.17 (0.6), respectively. At 18 months, mean (SD) expressive vocabulary score was 32 (24) words and median (interquartile range) skills successfully performed for fine, gross, and overall motor skills were 21 (19–22), 18 (16–19), and 38 (26–40), respectively. Breast milk intake (g/day) was not associated with either growth or development. Proportion of total energy intake from breast milk was negatively associated with fine motor (β = −0.18, p = .015) but not other developmental scores in models adjusted for potential confounders. Among Malawian infants, neither breast milk intake nor percent of total energy intake from breast milk at 9–10 months was positively associated with subsequent growth between 12 and 18 months, or development at 18 months. [ABSTRACT FROM AUTHOR]

Human growth and development are depended on both genetic and environmental conditions. From infancy to adulthood, during the growth process the growth rate of the body ratios shows differences. The purpose of the present study is to evaluate height, upper arm, forearm, upper leg, lower leg length values of the pre-school children and to determinate the ratios, and contribute to other public health studies. The study sample consisted of 815 (402 male, 413 female) children aged between 3 and 5 years living in Ankara. Height, upper arm, forearm, upper leg, and lower leg lengths were taken in accordance with the standard protocols after receiving ethical and family permits. The statistical analyses conducted using SPSS 20.0 program and percentiles were constructed using LMS method. According to the results, children aged between 3 to 5 years, the forearm / upper ratio was 0.8 and the lower / upper ratio was 0.7 in both sexes. Positive correlation was found between all variables (p <0.001). The comparison of study results with other country values revealed that upper arm length was lower than the American children (Centers for Disease Control and Prevention (CDC)) for the respective age groups. Constructing the country specific reference values is of great importance for to follow-up children's development, to evaluate and compare for further generations and to determinate the secular changes. [ABSTRACT FROM AUTHOR]

Background and Objectives: To evaluate the effect of culturally-relevant food supplementation and psychosocial stimulation on infant growth and development.Methods and Study Design: A community-based randomized controlled trial was conducted in 40 clusters from 5 selected villages in Tanah Datar District of West Sumatera, Indonesia. We assessed 355 infants aged 6 to 9 months at the beginning of the study. The infants were divided into 4 groups: 1) Food Supplementation (FS); 2) Psychosocial Stimulation (PS); 3) Food Supplementation and Psychosocial Stimulation (FS+PS); and 4) Control Group (CG). The formula food supplement was comprised of a variety of local food sources (local MP-ASI) and adjusted for the local habits. The quality of psychosocial stimulation was assessed with the Infant HOME inventory method. Progress at 6 months was assessed by anthropometry and the Bayley scores of cognition, language and motor function.Results: There were improvements in linear growth, cognitive and motor development of children in the FS (p<0.05) and the FS+PS (p<0.01) groups compared to the CG. After six months of intervention, mean length increased to 6.86±2.08 cm and 6.66±2.41 cm for FS and FS+PS respectively (p<0.05). With the combination of food supplementation and psychosocial stimulation (FS+PS), cognitive development increased to 21.4±12.2 points (effect size 0.56) (p<0.01) and motor development increased to 20.7±18.4 points (effect size 0.50) (p<0.001).Conclusion: Combined intervention with local food supplementation and psychosocial stimulation improved infant growth, cognitive and motor development. [ABSTRACT FROM AUTHOR]

We studied the association of dental maturity with body mass index ( BMI), energy intake, and macronutrient intake. A randomly selected subset ( n = 148) of the Special Turku Coronary Risk Factor Intervention Project ( STRIP) was invited to an oral follow-up study, and the 6- and 12-yr-examination data ( n = 111, 60 boys) were used. Food records for four consecutive days and BMI values were extracted from the databank of the main STRIP project. The developmental stage of seven permanent mandibular teeth was assessed using panoramic radiographs. The resulting maturity scores were converted to dental age estimates. Three dental-maturity groups (delayed, average, and advanced) and two BMI groups [normal BMI (≤mean+1 SD) and high BMI (>mean+1 SD)] were formed. The dental age was higher than the chronological age by 0.6-0.8 yr. Maturity scores for girls were statistically significantly higher than for boys. The distribution of girls into dental-maturity groups at age 12 yr was different from that of the boys and there were more boys than girls among the high- BMI group. Children of the advanced dental-maturity group had a statistically significantly higher energy intake than children in the other groups. We conclude that advanced dental maturity is associated with higher energy intake. [ABSTRACT FROM AUTHOR]

Objective: The aim of this study was to evaluate whether an iron-fortified formula with a concentration of lactoferrin would significantly improve the hematologic indexes and iron status in term infants compared with those same values in infants fed an iron-fortified formula without lactoferrin. Method: In this prospective, multicenter, controlled intervention study, 260 infants ages 4 to 6 mo were selected from six maternal and children's health care hospitals in the area. All infants were divided into two groups with the sequence of outpatient: lactoferrin-fortified formula milk group (fortified group, FG, containing lactoferrin 38 mg/100 g milk and iron element 4 mg/100 g milk) and no lactoferrin fortified milk (control group, CG, containing lactoferrin 0 mg/100 g milk and iron element 4 mg/100 g milk) for 3 mo. The levels of weight, height, and head circumference and the concentration of hemoglobin (Hb), serum ferritin (SF), and serum transferring receptor (sTfR) were measured and sTfR-SF index (TFR-F index), total body iron content (TBIC) and low height for age (HAZ), low weight for age (WAZ), and low weight for height (WHZ) were computed before and after the intervention, respectively. Results: In all, 213 (115 in FG and 98 in CG) infants completed the intervention trial and all measurements of biochemical indicators. There were no significant differences in the average amount of daily intake of formula milk (94.3 ± 9.8 g versus 88.2 ± 8.7 g for FG and CG; P > 0.05) and iron element (3.8 ± 0.4 mg versus 3.7 ± 0.6 mg for FG and CG; P > 0.05). The average amount of daily intake of lactoferrin for infants in FG group was 35.8 ± 3.7 mg. The levels of weight, WAZ, WHZ, Hb, SF, TFR-F index, and TBIC after intervention of infants in FG were all significantly higher than those of infants in CG weight, 8723 ± 245 g versus 8558 ± 214g; WAZ, 1.02 ± 0.31 versus 0.44 ± 0.18; WHZ, 0.98 ± 0.31 versus 0.41 ± 0.12; Hb, 125.5 ± 15.4 g/L versus 116.9 ± 13.1 g/L; SF, 44.7 ± 17.2 mg/ L versus 31.6 ± 18.4 mg/L; TFR-F index, 1.88 ± 0.41 versus 1.26 ± 0.39; TBIC, 6.12 ± 0.78 mg/kg versus 5.26 ± 0.55 mg/kg for FG and CG; P < 0.05), but significantly lower (P < 0.05) for the prevalence of anemia (4.1% versus 7.5%), iron deficiency (13.9% versus 24.4%), and iron-deficient anemia (1.7% versus 6.1%). Conclusion: When infants who were exclusively breastfed were supplemented with lactoferrin-fortified milk, significant increases in TBIC and iron absorption in the intestine were seen. [ABSTRACT FROM AUTHOR]

Objective: When the dimensional measurements of the students who spend most of their time at school are taken into consideration, inappropriate dimensions of school equipment may affect their body and psychological improvements negatively. Anthropometric measurements are necessary for designing the educational equipment of the children at school. It is emphasized that anthropometric measurements of the people living in different climate and altitude conditions w ill be different. It is mentioned that anthropometric data available for a certain region will be able to change as a result of changing socio-economical conditions and therefore, anthropometric data update is necessary at certain periods. Materials and Methods: In 2000 anthropometric data obtained from the children between the age of seven and fifteen, who were in sitting and standing positions, were measured with a repeated measurement in the same schools in 2007. Results: Mean values of the heights of elbow at standing position of the female students, 8 years old, increased from 72.38 cm in 2000 to 74.67 cm in 2007 (p<0.001). Most of the other measurements in 2007 were larger than those in 2000, giving the impression that new generation children are getting larger in size. Conclusion: As reported in the literature, anthropometric data should be updated at certain period of times. [ABSTRACT FROM AUTHOR]