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Increasingly, high-risk pregnant women opt for non-invasive prenatal testing (NIPT) instead of invasive diagnostic testing. Since NIPT is less accurate than invasive testing, a normal NIPT result might leave women less reassured. A questionnaire study was performed among pregnant women with elevated risk for fetal aneuploidy based on first-trimester combined test (risk ≥1:200) or medical history, who were offered NIPT in the nationwide Dutch TRIDENT study. Pre- and post-test questionnaires (n = 682) included measures on: experiences with NIPT procedure, feelings of reassurance, anxiety (State-Trait Anxiety Inventory, STAI), child-related anxiety (PRAQ-R), and satisfaction. The majority (96.1%) were glad to have been offered NIPT. Most (68.5%) perceived the waiting time for NIPT results (mean: 15 days, range 5–32) as (much) too long. Most women with a normal NIPT result felt reassured (80.9%) or somewhat reassured (15.7%). Levels of anxiety and child-related anxiety were significantly lower after receiving a normal NIPT result as compared to the moment of intake (p

The human placenta is essential for the supply of the fetus. To monitor the fetal development, imaging data is acquired using (US). Although it is currently the gold-standard in fetal imaging, it might not capture certain abnormalities of the placenta. (MRI) is a safe alternative for the in utero examination while acquiring the fetus data in higher detail. Nevertheless, there is currently no established procedure for assessing the condition of the placenta and consequently the fetal health. Due to maternal respiration and inherent movements of the fetus during examination, a quantitative assessment of the placenta requires fetal motion compensation, precise placenta segmentation and a standardized visualization, which are challenging tasks. Utilizing advanced motion compensation and automatic segmentation methods to extract the highly versatile shape of the placenta, we introduce a novel visualization technique that presents the fetal and maternal side of the placenta in a standardized way. Our approach enables physicians to explore the placenta even in utero. This establishes the basis for a comparative assessment of multiple placentas to analyze possible pathologic arrangements and to support the research and understanding of this vital organ. Additionally, we propose a three-dimensional structure-aware surface slicing technique in order to explore relevant regions inside the placenta. Finally, to survey the applicability of our approach, we consulted clinical experts in prenatal diagnostics and imaging. We received mainly positive feedback, especially the applicability of our technique for research purposes was appreciated.

Anne Yaşının İkili Tarama Testi Öncesi Kaygı Düzeyine EtkisiAmaç: Araştırmanın amacı, anne yaşının ikili tarama testi öncesi kaygı düzeyine etkisini saptamaktır.Materyal Metod: İlişkisel-tanımlayıcı olarak tasarlanan bu araştırma, bir üniversite hastanesinin Kadın Doğum Polikliniğine 14 Ağustos 2014- 13 Ocak 2017 tarihleri arasında ikili tarama testi yaptırmak amacıyla başvuran 232 gebe ile yürütülmüştür. Verilerin toplanmasında Durumluluk Kaygı Ölçeği ve Kişisel Tanıtım Formu kullanılmıştır. Verilerin analizinde; Tek yönlü varyans analizi, Pearson Korelasyonu ve Cronbach's Alfa Güvenirlik Analiz Testi kullanılmıştır.Bulgular: Araştırmaya katılan gebelerin yaş ortalamasının 27.35±6.42 olduğu ve %15.9'unun 15-19 yaş, %65.9'unun 20-34 yaş ve %18.9'unun ise ≥35 yaş grubunda yer aldığı saptanmıştır. Yaş ve Durumluluk Kaygı Ölçeği puanları arasında pozitif yönde orta düzeyde istatiksel olarak anlamlı ilişki olduğu (r=0.572) (p