13 results on '"Li, Jian"'
Search Results
2. Predictive value of elevated alanine aminotransferase for in-hospital mortality in patients with acute myocardial infarction
- Author
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Li, Jian, Zhao, Zhuo, Jiang, Hui, Jiang, Minjie, Yu, Ge, and Li, Xu
- Published
- 2021
- Full Text
- View/download PDF
3. A patient with acute myocardial infarction with electrocardiogram Aslanger's pattern.
- Author
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Liu, Ming-hao, Li, Hao, Li, Ang, Liu, Ru, Liu, Hai-bo, Gao, Li-jian, Gu, Qing, and Song, Lei
- Subjects
MYOCARDIAL infarction ,BRUGADA syndrome ,ACUTE coronary syndrome ,CORONARY angiography ,TROPONIN I ,CORONARY arteries - Abstract
Background: Aslanger's pattern in electrocardiogram (ECG) indicates that patients may have acute inferior myocardial infarction(AMI) with concomitant critical stenoses on other coronary arteries, which needs to be evaluated the timing of revascularization as risk equivalents of ST elevation myocardial infarction(STEMI). Case Presentation: The patient was a 62-year-old male with chief complaint of intermittent exertional subxiphoid pain for 20 days from 30th June. One day after the last episode (19th July), the 18-lead electrocardiogram showed ST segment elevation of 0.05-0.1mV in lead III, ST segment depression in leads I, avL, and V2-V6, T wave inversion with positive terminal vector in lead V4-V5, and positive T wave in lead V6, which indicated Aslanger's pattern. With increased Troponin I (0.162ng/mL, 0-0.02), The patient was diagnosed as acute non-ST-segment elevation myocardial infarction (NSTEMI) and admitted to coronary ward on 20th July. The coronary angiography showed 95% stenosis in the distal left main coronary artery (LM) to the ostium of the left anterior descending artery (LAD), 90% stenosis in the proximal segment of the LAD, and 80% stenosis in the middle segment of the LAD, and TIMI blood flow was graded score 2. Three drug-eluting stents were implanted at the lesions. The patient's ECG returned close to normal one month after revascularization. Conclusion: We presented an acute coronary syndrome case whose ECG showed with Aslanger's pattern (i.e., isolated ST-segment elevation in lead III, associated ST-segment depression in lead V4-V6 with positive T wave/terminal vector, and greater ST-segment elevation in lead V1 than in lead V2), and was confirmed severe stenosis of the LM and the proximal segment of the LAD via coronary angiography. In clinical practice, especially in the emergency, patients with ECG presenting Aslanger's pattern should be urgently evaluated with prompt treatment, and the timing of emergency coronary angiography and revascularization should be evaluated to avoid adverse outcomes caused by delayed treatment. [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
- View/download PDF
4. Differential leukocyte counts and cardiovascular mortality in very old patients with acute myocardial infarction: a Chinese cohort study
- Author
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Yan, Xiao-Ni, Jin, Jing-Lu, Zhang, Meng, Hong, Li-Feng, Guo, Yuan-Lin, Wu, Na-Qiong, Zhu, Cheng-Gang, Dong, Qian, and Li, Jian-Jun
- Published
- 2020
- Full Text
- View/download PDF
5. Venoarterial extracorporeal membrane oxygenation improves survival in a rat model of acute myocardial infarction.
- Author
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Wei, Shilin, Cheng, Xingdong, Li, Jian, Zhai, Kerong, Huang, Jian, Wang, Shixiong, Li, Yongnan, and Liu, Debin
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MYOCARDIAL infarction ,EXTRACORPOREAL membrane oxygenation ,JUGULAR vein ,ANIMAL disease models ,HEMATOXYLIN & eosin staining ,BLOOD pressure ,FEMORAL artery ,BLOOD gases - Abstract
Background: Venoarterial extracorporeal membrane oxygenation (VA‐ECMO) has been widely used in high‐risk acute myocardial infarction (AMI) patients with promising outcomes. However, the underlying molecular mechanisms remain unknown and a VA‐ECMO animal model has not yet been established. The purpose of this study was to establish a VA‐ECMO model in AMI rats and evaluate long‐term cardiac function. Methods: We first established AMI in 20 Sprague–Dawley (SD) rats by ligating the left anterior descending coronary artery, while five rats underwent a thoracotomy to form the sham group. VA‐ECMO was established after 30mins of AMI in 10 rats through the right jugular vein for venous drainage and right femoral artery for arterial infusion. Arterial blood pressure was monitored using a catheter in the left femoral artery, blood gas parameters were measured using a blood gas analyzer, while myocardial enzymes were detected using an ELISA Kit. Cardiac function was assessed through echocardiography on day 15. Masson staining and Western Blot were used for evaluating myocardial fibrosis, while histological injury was evaluated using hematoxylin and eosin staining. Results: VA‐ECMO support stabilized blood pressure, decreased the levels of myocardial enzymes including cTnI, cTnT, CK‐MB, and was associated with a higher survival rate. In the long term, the VA‐ECMO group showed improved cardiac function, significantly increased EF and FS but significantly decreased EDV and ESV compared to the AMI group. Furthermore, VA‐ECMO significantly alleviated pathological damage and myocardial fibrosis. Conclusion: We established an economical, reliable, and reproducible VA‐ECMO animal model in AMI rats, and demonstrated that VA‐ECMO support prevents deteriorated cardiac function. [ABSTRACT FROM AUTHOR]
- Published
- 2023
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- View/download PDF
6. Corrigendum: The Prevalence of Familial Hypercholesterolemia (FH) in Chinese Patients With Acute Myocardial Infarction (AMI): Data From Chinese Acute Myocardial Infarction (CAMI) Registry
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Shi, Hui-Wei, Yang, Jin-Gang, Wang, Yang, Li, Wei, Guo, Yuan-Lin, Gao, Ying, Tang, Yi-Da, Li, Jian-Jun, Wu, Na-Qiong, and Yang, Yue-Jin
- Subjects
heterozygous familial hypercholesterolemia ,lcsh:Diseases of the circulatory (Cardiovascular) system ,Chinese ,clinical manifestations ,lcsh:RC666-701 ,prevalence ,Correction ,acute myocardial infarction ,Cardiovascular Medicine ,Cardiology and Cardiovascular Medicine - Published
- 2020
7. Acute myocardial infarction in patients of nephrotic syndrome: a case series
- Author
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Xie, Liang, Tang, Yi, Liu, Jing, He, Song-Qing, Li, Jian-Hua, Zhu, Ying, Liu, Zheng-Bing, Cheng, Zhen, and Gong, Jian-Bin
- Subjects
Membranous nephropathy ,Nephrotic syndrome ,Acute myocardial infarction ,Letter to the Editor - Published
- 2017
8. Predictive value of elevated alanine aminotransferase for in-hospital mortality in patients with acute myocardial infarction.
- Author
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Jian Li, Zhuo Zhao, Hui Jiang, Minjie Jiang, Ge Yu, Xu Li, Li, Jian, Zhao, Zhuo, Jiang, Hui, Jiang, Minjie, Yu, Ge, and Li, Xu
- Subjects
MYOCARDIAL infarction ,ALANINE aminotransferase ,HOSPITAL mortality ,LIVER enzymes ,FATTY liver - Abstract
Background and Aims: Liver enzymes, including alanine aminotransferase (ALT) and aspartate aminotransferase (AST), are markers of hepatic dysfunction and fatty liver disease. Although ALT and AST have been suggested as risk factors for cardiovascular disease, their role as predictors of mortality after acute myocardial infarction (AMI) has not been established. The objective of this study was to investigate the predictive value of ALT and AST for mortality in patients with AMI.Methods: We analyzed records of 712 patients with AMI and no known liver disease treated at the Department of Cardiovascular Center in the First Hospital of Jilin University. The primary outcome was all-cause in-hospital mortality. Relationships between primary outcome and various risk factors, including serum transaminase levels, were assessed using multivariate logistic regression analysis.Results: Age (P < 0.001), hypertension (P = 0.034), prior myocardial infarction (P < 0.001), AST (P < 0.001), ALT (P < 0.001), creatinine (P = 0.007), blood urea nitrogen (P = 0.006), and troponin I (P < 0.001) differed significantly between ST-segment elevation myocardial infarction (STEMI) and non-STEMI. The following factors were associated with an increased risk of in-hospital all-cause mortality in patients with AMI: ALT ≥ 2ULN (adjusted odds ratio [AOR] 2.240 [95% confidence interval (CI), 1.331-3.771]; P = 0.002); age ≥ 65 year (AOR 4.320 [95% CI 2.687-6.947]; P < 0.001); increased fasting plasma glucose (FPG) (AOR 2.319 [95% CI 1.564-3.438]; P < 0.001); elevated D-dimer (AOR 2.117 [95% CI 1.407-3.184]; P < 0.001); elevated fibrinogen (AOR 1.601 [95% CI 1.077-2.380]; P = 0.20); and reduced estimated glomerular filtration rate (eGFR) (AOR 2.279 [95% CI 1.519-3.419]; P < 0.001).Conclusions: Our findings demonstrated that elevated ALT was independently associated with increased in-hospital all-cause mortality in patients with AMI. Other risk factors were increased age, FPG, D-dimer, and fibrinogen and decreased eGFR. [ABSTRACT FROM AUTHOR]- Published
- 2021
- Full Text
- View/download PDF
9. Lipoprotein(a) as a marker for predicting coronary collateral circulation in patients with acute myocardial infarction.
- Author
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You, Xiang-Dong, Jin, Jing-Lu, Zhang, Hua, Guo, Na, Hou, Bing-Jie, Guo, Yuan-Lin, Wu, Na-Qiong, Zhu, Cheng-Gang, and Li, Jian-Jun
- Abstract
Aim: The aim of the present study was to examine the predictive value of lipoprotein(a) (Lp[a]) levels for coronary collateral circulation (CCC) in patients with acute myocardial infarction (AMI). Method & methods: A total of 409 consecutive patients with AMI were enrolled for this study. Patients were divided into two groups according to rentrop grades assessed by coronary angiography: bad (n = 277) and good CCC group (n = 132). Result: Patients with bad CCC had a higher level of Lp(a) than that with good CCC (median Lp[a] 219.1 vs 122.0 mg/l). The area under the receiver-operating characteristic curves of Lp(a) in predicting bad CCC was 0.647 (95% CI: 0.592–0.702) with the cut-off value of 199.0 mg/l. Conclusion: Our data firstly suggested that Lp(a) might be a useful marker for CCC after AMI. [ABSTRACT FROM AUTHOR]
- Published
- 2020
- Full Text
- View/download PDF
10. Electrocardiographic findings of acute total occlusion associated with a sub-occlusion involving the left anterior descending and the right coronary artery.
- Author
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Zhan, Zhong-Qun, Li, Yang-Hua, Li, Yang, Li, Jian-Ping, and Nikus, Kjell C.
- Abstract
Background: The ECG characteristics of simultaneous acute occlusion/sub-occlusion of two coronary arteries involving the left anterior descending (LAD) and right (RCA) coronary artery have been rarely described in the literature.Methods: We present two patient cases, where one of the arteries was totally occluded and the other one had a sub-occlusion with severely limited flow to demonstrate the ECG characteristics of this severe presentation of acute coronary syndrome.Results: Two ECG patterns suggested simultaneous occlusions of the RCA and LAD. One pattern was ST-segment elevation (STE) in lead III higher than in lead II with concomitant STE in leads V3-V4. The other pattern was STE in lead III higher than in lead II with the concomitant Dressler - de Winter ECG pattern in leads V2-V4.Conclusions: We present two ECG presentations of simultaneous RCA and LAD occlusion/sub-occlusion. We consider these ECG features as high-risk markers in acute ST-elevation myocardial infarction. [ABSTRACT FROM AUTHOR]- Published
- 2019
- Full Text
- View/download PDF
11. Correlation of ABO blood groups with spontaneous recanalization in acute myocardial infarction.
- Author
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Lin, Xian-Liang, Zhou, Bing-Yang, Li, Sha, Li, Xiao-Lin, Luo, Zhu-Rong, and Li, Jian-Jun
- Subjects
MYOCARDIAL infarction treatment ,ACUTE diseases ,THROMBOLYTIC therapy ,BLOOD flow ,MULTIVARIATE analysis ,ABO blood group system ,CORONARY circulation ,CORONARY disease ,LOGISTIC regression analysis ,DISEASE remission ,CORONARY angiography ,ODDS ratio - Abstract
Objectives: Although previous studies have demonstrated the relationship between ABO blood groups and cardiovascular disease, the association of ABO blood type with spontaneous recanalization (SR) in patients with acute myocardial infarction (AMI) has not been previously investigated.Methods: We performed an initial exploratory study on the association of ABO blood groups with the presence of SR in 1209 patients with AMI. They were divided into two groups according to the thrombolysis in myocardial infarction (TIMI) grades: no-SR group (TIMI 0-1, n = 442) and SR group (TIMI 2-3, n = 767). To confirm our primary findings, data from a second AMI population (n = 200) was analyzed.Results: In the initial data, SR group had a significantly higher percentage of blood type O and a lower percentage of blood type A compared to the no-SR group. Multivariate logistic regression analysis showed that blood type O was positively associated with SR (odds ratio: 1.40, 95% confidence interval: 1.05-1.87, p = .02), and this finding was confirmed in our second population.Conclusion: The present study demonstrates that blood type O was independently and positively associated with an open culprit artery in patients with AMI, suggesting that the ABO blood type is not only associated with the susceptibility to coronary artery disease but also to spontaneous reperfusion in AMI patients. [ABSTRACT FROM AUTHOR]- Published
- 2017
- Full Text
- View/download PDF
12. A patient with acute myocardial infarction with electrocardiogram Aslanger’s pattern
- Author
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Ming-hao Liu, Hao Li, Ang Li, Ru Liu, Hai-bo Liu, Li-jian Gao, Qing Gu, and Lei Song
- Subjects
Aslanger’s pattern ,Acute Myocardial Infarction ,ST-segment elevation ,Critical coronary stenoses ,Revascularization ,Diseases of the circulatory (Cardiovascular) system ,RC666-701 - Abstract
Abstract Background Aslanger’s pattern in electrocardiogram (ECG) indicates that patients may have acute inferior myocardial infarction(AMI) with concomitant critical stenoses on other coronary arteries, which needs to be evaluated the timing of revascularization as risk equivalents of ST elevation myocardial infarction(STEMI). Case Presentation The patient was a 62-year-old male with chief complaint of intermittent exertional subxiphoid pain for 20 days from 30th June. One day after the last episode (19th July), the 18-lead electrocardiogram showed ST segment elevation of 0.05-0.1mV in lead III, ST segment depression in leads I, avL, and V2-V6, T wave inversion with positive terminal vector in lead V4-V5, and positive T wave in lead V6, which indicated Aslanger’s pattern. With increased Troponin I (0.162ng/mL, 0-0.02), The patient was diagnosed as acute non-ST-segment elevation myocardial infarction (NSTEMI) and admitted to coronary ward on 20th July. The coronary angiography showed 95% stenosis in the distal left main coronary artery (LM) to the ostium of the left anterior descending artery (LAD), 90% stenosis in the proximal segment of the LAD, and 80% stenosis in the middle segment of the LAD, and TIMI blood flow was graded score 2. Three drug-eluting stents were implanted at the lesions. The patient’s ECG returned close to normal one month after revascularization. Conclusion We presented an acute coronary syndrome case whose ECG showed with Aslanger’s pattern (i.e., isolated ST-segment elevation in lead III, associated ST-segment depression in lead V4-V6 with positive T wave/terminal vector, and greater ST-segment elevation in lead V1 than in lead V2), and was confirmed severe stenosis of the LM and the proximal segment of the LAD via coronary angiography. In clinical practice, especially in the emergency, patients with ECG presenting Aslanger’s pattern should be urgently evaluated with prompt treatment, and the timing of emergency coronary angiography and revascularization should be evaluated to avoid adverse outcomes caused by delayed treatment.
- Published
- 2024
- Full Text
- View/download PDF
13. The association between Day-1 urine cadmium excretion and 30-day mortality in patients with acute myocardial infarction: A multi-institutional cohort study.
- Author
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Lin, Hung-Chen, Chou, Shing-Hsien, Fan, Pei-Chun, Zhu, Zhidong, Pan, Junjie, Li, Jian, Chang, Chih-Hsiang, Wu, Victor Chien-Chia, Chen, Shao-Wei, and Chu, Pao-Hsien
- Subjects
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MYOCARDIAL infarction , *CADMIUM , *EXCRETION , *RETENTION of urine , *COHORT analysis , *URINE , *MORTALITY - Abstract
The aim of this study was to investigate the relationship between day-1 urine cadmium excretion and 30-day mortality in patients with acute myocardial infarction (AMI) at two centers. A total of 286 patients (222 males and 64 females) with AMI from Huashan Hospital, Shanghai and Chang Gung Memorial Hospital, Taiwan were enrolled. Basic vital signs, history, laboratory results, and day-1 urine excretion of cadmium (D1UECd) were recorded. Disease severity was assessed during the first hospitalization using Killip score, APACHE II score, and SOFA score. The main endpoint was 30-day mortality. Among the 286 patients, 218 were from Chung Gung Memorial Hospital and 68 were from Huashan Hospital with an average age of 64.2 years. Forty (14%) patients died within 30 days after AMI. The average 24-h urine cadmium level among the Chung Gung Memorial Hospital cohort was 1.5 ± 2.4 μg compared to 1.7 ± 1.7 μg among Huashan Hospital cohort, both higher than the local populations. A higher D1UECd level was significantly associated with a greater risk of 30-day mortality (odds ratio 1.68, 95% confidence interval 1.30–2.16) after controlling for a number of covariates. The ability of D1UECd to discriminate 30-day mortality was excellent, with a very high area under the curve (87.2%, 95% CI 82.0–92.5%). D1UECd was positively correlated and an independent predictor of 30-day mortality in the enrolled AMI patients. D1UECd may be a simple, objective prognostic scoring system in AMI patients. • Day-1 urine excretion of cadmium is positively correlated and an independent predictor of 30-day mortality in the enrolled AMI patients. • The prognosis predictive value of Day-1 urine excretion of cadmium is better than Killip, APACHE II and SOFA. [ABSTRACT FROM AUTHOR]
- Published
- 2023
- Full Text
- View/download PDF
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