Search

Background: Proteins in the urine of women with preeclampsia (PE) bind Congo Red dye (urine congophilia). We sought to determine the diagnostic performance of a paper-based point-of-care test detecting urine congophilia for rapid triage and diagnosis of PE. Methods: Prospective cohort study conducted in 346 consecutive pregnant women evaluated for PE in the Labour and Delivery triage unit at our institution. The Congo Red Dot (CRD) Paper Test (index test) was performed on fresh urine samples. The CRD Paper Test results were compared to an expert adjudicated diagnosis in each case. The accuracy of the CRD Paper Test was also compared to urine and serum analytes (placental growth factor and soluble fms-like tyrosine kinase-1) previously proposed as diagnostic aids for PE. Findings: During the first triage visit, 32% (112/346) of women received a clinical diagnosis of PE. Yet, 63% (217/346) were admitted for in-patient diagnostic work-up or delivery. The CRD Paper Test was positive in 25% (86/346) of the cases. Adjudication confirmed PE in 28% (96/346) of all cases. The CRD Paper Test outperformed measured serum and urine markers (80·2% sensitivity, 89·2% specificity, 92·1% negative predictive value, 86·7% accuracy). The pre-test, positive and negative post-test probabilities were 27·7%, 74·0%, and 8·0%, respectively. Of women who were discharged undelivered, 38% (133/346) had at least one additional triage visit and the interval between the last negative and first positive CRD Paper Test was 12 (interquartile range, [5–34]) days. Interpretation: The CRD Paper Test is a simple, non-invasive, “sample-in/answer-out” point-of-care clinical tool for rapid identification of PE. Funding: Saving Lives at Birth Program and NICHD. Keywords: Preeclampsia, Cohort study, Congophilia, Misfolded proteins, Point-of-care

Suicide is a major global public health issue, and in recent years, there has been increasing recognition of the problem of physician suicide. This American College of Physicians policy paper examines, from the perspective of ethics, the issues that arise when individuals and institutions respond to physician suicides and when they engage in broader efforts aimed at physician suicide prevention. Emphasizing the medical profession as a unique moral community characterized by ethical and professional commitments of service to patients, each other, and society, this paper offers guidance regarding physician suicide and the role of a healing community. The response to an individual physician suicide should be characterized by respect and concern for those who are grieving, the creation of a supportive environment for suicide loss survivors, and careful communication about the event. Because suicide is a complex problem, actions aimed at preventing suicide must occur at the individual, interpersonal, community, and societal levels. The medical community has an obligation to foster a culture that supports education, screening, and access to mental health treatment, beginning at the earliest stages of medical training.

Evolutionary game dynamics is a combination of game theory and dynamical systems. Using dynamical theory, we investigate chaotic behavior in asymmetric Rock-Paper-Scissors games under imitative dynamics with two different populations. Our theoretical analysis and numerical simulations demonstrate that the dynamical system can give rise to chaotic behavior in zero-sum and positive-sum asymmetric games. However, chaos cannot occur in a negative-sum asymmetric game. In particular, the numerical simulations show that there is a limit cycle in a negative-sum asymmetric game.

Objectives This document provides an English translation of the Israeli Joint Commission's national guidelines for triaging severely ill patients during the coronavirus disease 2019 (COVID-19) pandemic. Methods Four subcommittees of medical, legal, ethical-social, and religious experts developed the general principles and practical medical criteria for triaging scarce life-saving resources. Results The guidelines provide an overview of general principles as well as pragmatic medical criteria and a practical triage protocol to be followed should the healthcare system be overwhelmed due to COVID-19. Issues covered include triggers for activating the guidelines, guiding ethical, legal, and religious principles, equity in access, fair distribution, transparency, consistency, palliation, medical policy prioritization, problem-solving mechanisms, and public trust. Conclusions The Israeli consensus document and pragmatic medical triage protocol offer a societal and medical roadmap for allocating scarce resources during the COVID-19 pandemic or other disasters.

We consider discrete dynamical systems coming from the models of evolution of populations playing rock - paper - scissors game . Asymptotic behaviour of trajectories of these systems is described, occurrence of the Neimark-Sacker bifurcation and nonexistence of time averages are proved.

In 2018, the American Glaucoma Society (AGS), the world’s largest professional society of glaucoma subspecialists, convened a 12-member task force of experts to craft a position statement about microinvasive glaucoma surgery (MIGS). The main objective of this position statement is to provide a succinct overview of these procedures and to address some misconceptions about MIGS. The members of the task force were selected by the AGS Board of Directors and include AGS members with expertise in developing MIGS, teaching MIGS, performing research on use and outcomes of these procedures, and working with the United States Food and Drug Administration (FDA) and other regulatory agencies about developing criteria to evaluate the efficacy and safety of these devices. Each of the sections of the position statement was prepared by subgroups of the task force, and then the material from the various sections was aggregated, and the leader of the task force (J.D.S.) merged the material into a cohesive draft. This draft was shared with the AGS Executive Committee and other members of the AGS Board of Directors for additional input.

In this work, a fine correlation among destructive and diagnostic parameters of transformer’s paper insulation is presented. The degree of polymerization (DP) directly assesses the condition of the paper insulation strength and is measured through destructive procedure. Generally, 2-FAL, CO2 and CO are the aging products of paper decomposition and referred as diagnostic parameters. An Adaptive Neuro Fuzzy Inference System (ANFIS) is proposed and developed to estimate the value of DP as the function of amount of diagnostic parameters. The proposed system has an advantage of diagnosing the health of solid insulation without performing destructive tests. The diagnostic parameters are taken as inputs to the system to determine the value of DP. The system uses 630 data points for training the ANFIS model and follows a ten-fold cross-validation approach. The average validation error has been determined to be. 0.0029. Further, the model’s performance has been assessed using experimental data. The optimal ANFIS model has been achieved by suitably selecting the number and type of membership function. The estimated value of DP has been found to conform to the experimental measurements for every case under test. The performance of this model has also been compared with a fuzzy inference system (FIS) model in the reported literature. The comparison shows that the ANFIS model determines the DP values with a greater degree of accuracy than the FIS model.

Objective This study examines the validity of optical mark recognition, a novel user interface, and crowdsourced data validation to rapidly digitize and extract data from paper COVID-19 assessment forms at a large medical center. Methods An optical mark recognition/optical character recognition (OMR/OCR) system was developed to identify fields that were selected on 2,814 paper assessment forms, each with 141 fields which were used to assess potential COVID-19 infections. A novel user interface (UI) displayed mirrored forms showing the scanned assessment forms with OMR results superimposed on the left and an editable web form on the right to improve ease of data validation. Crowdsourced participants validated the results of the OMR system. Overall error rate and time taken to validate were calculated. A subset of forms was validated by multiple participants to calculate agreement between participants. Results The OMR/OCR tools correctly extracted data from scanned forms fields with an average accuracy of 70% and median accuracy of 78% when the OMR/OCR results were compared with the results from crowd validation. Scanned forms were crowd-validated at a mean rate of 157 seconds per document and a volume of approximately 108 documents per day. A randomly selected subset of documents was reviewed by multiple participants, producing an interobserver agreement of 97% for documents when narrative-text fields were included and 98% when only Boolean and multiple-choice fields were considered. Conclusion Due to the COVID-19 pandemic, it may be challenging for health care workers wearing personal protective equipment to interact with electronic health records. The combination of OMR/OCR technology, a novel UI, and crowdsourcing data-validation processes allowed for the efficient extraction of a large volume of paper medical documents produced during the COVID-19 pandemic.

Racial and ethnic minority populations in the United States experience disparities in their health and health care that arise from a combination of interacting factors, including racism and discrimination, social drivers of health, health care access and quality, individual behavior, and biology. To ameliorate these disparities, the American College of Physicians (ACP) proposes a comprehensive policy framework that recognizes and confronts the many elements of U.S. society, some of which are intertwined and compounding, that contribute to poorer health outcomes. In addition to this framework, which includes high-level principles and discusses how disparities are interconnected, ACP offers specific policy recommendations on disparities and discrimination in education and the workforce, those affecting specific populations, and those in criminal justice practices and policies in its 3 companion policy papers. ACP believes that a cross-cutting approach that identifies and offers solutions to the various aspects of society contributing to poor health is essential to achieving its goal of good health care for all, poor health care for none.

The prescription drug market in the United States relies on competition to keep prices reasonable. Although many policies have been implemented to spur competition and decrease costs for patients, these policies may be outdated and should be redesigned and updated to achieve success in the current prescription drug market. In this paper, the American College of Physicians (ACP) proposes that new policies should be implemented to prevent market manipulation, help lower-cost alternatives make it to the market faster, and ensure a robust and competitive market for generic and biosimilar drugs. The ACP believes these changes will have a meaningful effect on patients without shifting costs to other areas of the health care system.

There are similarities between Drinfeld modules and abelian varieties. The purpose of this paper is to investigate these similarities in terms of supersingularity. More specifically, we provide explicit formulas of Hasse invariants (or, equivalently, of supersingular polynomials) for Drinfeld modules, which is a continuation of the 2013 paper by Ahmad El-Guindy and Matthew A. Papanikolas. We present several supersingular Drinfeld modules as an application.

The variability and interdependence of local porosity and local mean geodesic tortuosity, which is a measure for the sinuosity of shortest transportation paths, is investigated at the example of the microstructure in sack paper. By means of statistical image analysis, these two morphological characteristics are computed for several cutouts of 3D image data obtained by X-ray microcomputed tomography. Considering cutouts of different sizes allows us to study the influence of the sample size on the local variability of the considered characteristics. Moreover, the interdependence between local porosity and local mean geodesic tortuosity is quantified by modeling their joint distribution parametrically using Archimedean copulas. It turns out that the family of Gumbel copulas is an appropriate model type, which is formally validated by a goodness of fit test. Besides mean geodesic tortuosity, we consider further related morphological characteristics, describing the sinuosity of those shortest transportation paths, whose minimum diameter exceeds a predefined threshold. Moreover, we show that the copula approach investigated in this paper can also be used to quantify the negative correlation between local porosity and these modified versions of local mean geodesic tortuosity. Our results elucidate the impact of local porosity on various kinds of morphological characteristics, which are not experimentally accessible and which are important for local air permeance – a key property of sack paper.

Even fairly good students, when they have obtained the solution of the problem and written down neatly the argument, shut their books and look for something else. Doing so, they miss an important a...

We present an English translation of Erwin Schr\"odinger's paper on "On the Reversal of the Laws of Nature". In this paper Schr\"odinger analyses the idea of time reversal of a diffusion process. Schr\"odinger's paper acted as a prominent source of inspiration for the works of Bernstein on reciprocal processes and of Kolmogorov on time reversal properties of Markov processes and detailed balance. The ideas outlined by Schr\"odinger also inspired the development of probabilistic interpretations of quantum mechanics by F\'enyes, Nelson and others as well as the notion of "Euclidean Quantum Mechanics" as probabilistic analogue of quantization. In the second part of the paper Schr\"odinger discusses the relation between time reversal and statistical laws of physics. We emphasize in our commentary the relevance of Schr\"odinger's intuitions for contemporary developments in statistical nano-physics., Comment: Revised version. 24 pages, 2 figures. Introduction 2 pages, Translation of the german original pag. 3-10, Commentary pag 10-22

In this short article, we mainly give some examples to prove that the main results of Section 4 of the paper [W. S. Liao and J. Wu, Ann. Func. Anal. 6 (2015), no. 3, 191–202] are not true. Then we give the corrected matrix inequalities.

Recent discussions about the increasing prices of prescription drugs have focused on pharmacy benefit managers (PBMs), third-party intermediaries for various types of employers and government purchasers who negotiate drug prices in health plans and thus play a crucial role in determining the amount millions of Americans pay for medications. In this position paper, the American College of Physicians expands on its position paper from 2016 by offering additional recommendations to improve transparency in the PBM industry and highlighting the need for reliable, timely, and relevant information on prescription drug pricing for physicians and patients.

The increasing price of prescription drugs is an ongoing concern for Medicare and Medicaid, particularly for patients with chronic health conditions who are using multiple medications and patients in these programs taking high-priced brand-name specialty drugs. Shifts in benefit design, including higher deductibles and a movement away from copayments to coinsurance, have increased patient out-of-pocket costs and put pressure on program budgets. In this paper, the American College of Physicians expands on its position paper from 2016 and offers additional recommendations to decrease out-of-pocket costs for patients, enhance the government's purchasing power, and address existing policies that add costs to the health care system.

Preliminary version. The published version contains a number of small modifications.; International audience; The present paper is a companion of two translated articles by Alfred Clebsch, titled "On a general transformation of the hydrodynamical equations" and "On the integration of the hydrodynamical equations". The originals were published in the Journal für die reine and angewandte Mathematik" (1857 and 1859). Here we provide a detailed critical reading of these articles, which analyzes methods, and results of Clebsch. In the first place, we try to elucidate the algebraic calculus used by Clebsch in several parts of the two articles that we believe to be the most significant ones. We also provide some proofs that Clebsch did not find necessary to explain, in particular concerning the variational principles stated in his two articles and the use of the method of Jacobi's Last Multiplier. When possible, we reformulate the original expressions by Clebsch in the language of vector analysis, which should be more familiar to the reader. The connections of the results and methods by Clebsch with his scientific context, in particular with the works of Carl Jacobi, are briefly discussed. We emphasize how the representations of the velocity vector field conceived by Clebsch in his two articles, allow for a variational formulation of hydrodynamics equations in the steady and unsteady case. In particular, we stress that what is nowadays known as the "Clebsch variables", permit to give a canonical Hamiltonian formulation of the equations of fluid mechanics. We also list a number of further developments of the theory initiated by Clebsch, which had an impact on presently active areas of research, within such fields as hydrodynamics and plasma physics.

Very recently Bordelles, Dai, Heyman, Pan and Shparlinski studied asymptotic behaviour of the quantity $$\begin{aligned} S_f(x) := \sum _{n\leqslant x} f\left( \left[ \frac{x}{n}\right] \right) , \end{aligned}$$and established some asymptotic formulas for $$S_f(x)$$ under three different types of assumptions on f. In this short note we improve some of their results.

Women comprise more than one third of the active physician workforce, an estimated 46% of all physicians-in-training, and more than half of all medical students in the United States. Although progress has been made toward gender diversity in the physician workforce, disparities in compensation exist and inequities have contributed to a disproportionately low number of female physicians achieving academic advancement and serving in leadership positions. Women in medicine face other challenges, including a lack of mentors, discrimination, gender bias, cultural environment of the workplace, imposter syndrome, and the need for better work-life integration. In this position paper, the American College of Physicians summarizes the unique challenges female physicians face over the course of their careers and provides recommendations to improve gender equity and ensure that the full potential of female physicians is realized.

Social determinants of health are nonmedical factors that can affect a person's overall health and health outcomes. Where a person is born and the social conditions they are born into can affect their risk factors for premature death and their life expectancy. In this position paper, the American College of Physicians acknowledges the role of social determinants in health, examines the complexities associated with them, and offers recommendations on better integration of social determinants into the health care system while highlighting the need to address systemic issues hindering health equity.

In this note we offer some criticism on the paper “On an identity for zeros of Bessel functions” by Baricz et al. [3] . The paper gives identities of type Stieltjes–Calogero for the sums of reciprocals of differences of fourth powers of zeros of Bessel functions. Although interesting in principle, by containing one too many sums of similar complexity the identities fail to convey the true spirit of the work of Stieltjes and Calogero. We rectify this by providing what we think is the correct type of identity for the above-said sums, in the general setup of entire functions of order

This study assessed the presence, amount, and sensitivity of personally identifiable information and personal health information found in hospital recycling bins in Toronto, Ontario, Canada.

© 2018 Association for Computing Machinery. Recursive programs can now be expressed as normal forms within some rewriting systems, including traditional combinatory logic, a new variant of lambda-calculus called closure calculus, and recent variants of combinatory logic that support queries of internal program structure. In all these settings, partial evaluation of primitive recursive functions, such as addition, can reduce open terms to normal form without fear of non-termination. In those calculi where queries of program structure are supported, program optimisations that are expressed as non-standard rewriting rules can be represented as functions in the calculus, without any need for quotation or other meta-theory.

This paper presents an example of how paper folding can be used in a geometry class to support conceptual understanding. Specifically, it explains an activity that constructs a rhombus and explores its attributes by using paper folding. The steps of constructing a rhombus are described and some discussion questions are given to consolidate understanding. © 2017 Informa UK Limited, trading as Taylor & Francis Group.

The environment in which physicians practice and patients receive care continues to change. Increasing employment of physicians, changing practice models, new regulatory requirements, and market dynamics all affect medical practice; some changes may also place greater emphasis on the business of medicine. Fundamental ethical principles and professional values about the patient-physician relationship, the primacy of patient welfare over self-interest, and the role of medicine as a moral community and learned profession need to be applied to the changing environment, and physicians must consider the effect the practice environment has on their ethical and professional responsibilities. Recognizing that all health care delivery arrangements come with advantages, disadvantages, and salient questions for ethics and professionalism, this American College of Physicians policy paper examines the ethical implications of issues that are particularly relevant today, including incentives in the shift to value-based care, physician contract clauses that affect care, private equity ownership, clinical priority setting, and physician leadership. Physicians should take the lead in helping to ensure that relationships and practices are structured to explicitly recognize and support the commitments of the physician and the profession of medicine to patients and patient care.

The paper alluded to in the title contains the following striking result: Let $I$ be the unit interval and $\Delta$ the Cantor set. If $X$ is a quasi Banach space containing no copy of $c_0$ which is isomorphic to a closed subspace of a space with a basis and $C(I, X)$ is linearly homeomorphic to $C(\Delta, X)$, then $X$ is locally convex, i.e., a Banach space. It is shown that Kalton result is sharp by exhibiting non locally convex quasi Banach spaces X with a basis for which $C(I, X)$ and $C(\Delta, X)$ are isomorphic. Our examples are rather specific and actually in all cases X is isomorphic to $C(\Delta, X)$ if $K$ is a metric compactum of finite covering dimension., Comment: 4 pages

Propositions 1.1–1.3 stated below contribute to results and certain problems considered in [E-S], on the behavior of products $$\Pi^n_1(1-z^{a_j}),1\leq{a_1}...\leq{a_n}$$ integers. In the discussion below, {a1,..., an} will be either a proportional subset of {1,..., n} or a set of large arithmetic diameter.

Publication doctorant; International audience; Our research team is specialized in human-computer systems and their engineering, with focus on interactive software systems for aeronautics (from cockpits to control towers). This context stands out by the need for certification, such as DO-178 or ED-12. Today, formal methods are pushed forward, as one of the best tools to achieve the verification and validation of properties, leading to the certification of these systems. Interactive systems are reactive computer systems that process information from their environment and produce a representation of their internal state. They offer new rich interfaces with sophisticated interactions. Their certification is a challenge, because the validation is often a human based process since traditional formal tools are not always suitable to the verification of graphical properties in particular.In this paper, we explore the scientific work that has been done in formal methods for interactive systems over the last decade, in a systematic study of publications in the International Workshop on Formal Methods for Interactive Systems. We describe an analytical framework that we apply to classify the studied work into classes of properties and used formalisms. We then discuss the emerging findings, mainly the lack of papers addressing the formal specification or validation of perceptibility properties. We conclude with an overview of our future work in this area.

We correct a mistake in a lemma in the paper cited in the title and show that it did not affect any of the other results of the paper. To this end, we prove results on linearly disjoint field extensions that do not seem to be commonly known. We give an example to show that a separability assumption in one of these results cannot be dropped (doing so had led to the mistake). Further, we discuss recent generalizations of the original classification of defect extensions.

The accelerated thermal aging test is an effective method to simulate insulation material degradation in oil-immersed transformers. Traditionally, cellulose paper and mineral oil are heated up together at the same temperature when a thermal aging test is conducted. However, variation occurs between laboratory results and field conditions. Temperature gradients exist in real transformers, and each part of the winding is aged under various conditions. In order to rebuild temperature gradients and conduct a thermal aging test under this condition. First, 3D models with designed U-shape wingding which can guarantee different parts aged simultaneously under different temperatures are calculated for temperature field analysis. Then a thermal aging platform with a large current generator is proposed to construct temperature gradients in a thermal aging test. The large current generator helps to heat up the copper winding. Temperature sensors are installed in the aging tank to monitoring winding and oil temperature and control temperature. The aging temperature is selected according to the standard IEC 60076-7 for the over-load condition. The degree of polymerisation of the insulation paper is measured and properties of each layer of the insulation paper are analysed. Other aging products under both traditional test and method in this study are compared.

For more than 20 years, the American College of Physicians (ACP) has advocated for the need to address firearm-related injuries and deaths in the United States. Yet, firearm violence continues to be a public health crisis that requires the nation's immediate attention. The policy recommendations in this paper build on, strengthen, and expand current ACP policies approved by the Board of Regents in April 2014, based on analysis of approaches that the evidence suggests will be effective in reducing deaths and injuries from firearm-related violence.

The goal of the Ending the HIV Epidemic Initiative is to reduce new infections in the United States by 90% by 2030. Success will require fundamentally changing human immunodeficiency virus (HIV) prevention and care delivery to engage more persons with HIV and at risk of HIV in treatment. While the coronavirus disease 2019 (COVID-19) pandemic reduced in-person visits to care facilities and led to concern about interruptions in care, it also accelerated growth of alternative options, bolstered by additional funding support. These included the use of telehealth, medication delivery to the home, and increased flexibility facilitating access to Ryan White HIV/AIDS Program services. While the outcomes of these programs must be studied, many have improved accessibility during the pandemic. As the pandemic wanes, long-term policy changes are needed to preserve these options for those who benefit from them. These new care paradigms may provide a roadmap for progress for those with other chronic health issues as well.

We discuss the recent paper by A. Dar\'os and L.K. Arruda (On the instability of elliptic traveling wave solutions of the modified Camassa-Holm equation, J. Diff. Equat., 266 (2019), 1946-1968). Our intention is to correct some imperfections left by the authors and present the orbital stability of periodic snoidal waves in the energy space., Comment: 10 pages and 2 figures

The purpose of this note is to discuss how paper folding can be used to find the exact trigonometric ratios of the following four angles: 22.5°, 67.5°, 27°, and 63°.

In a recent paper referred to in the title, the author used the concept of quasi self-adjointness to obtain conservation laws for a system of the ( 2 + 1 ) -dimensional Bogoyavlensky–Konopelchenko equation. Apart from the adjoint system of equations, all the results on the quasi self-adjointness and the subsequent conservation laws obtained are inaccurate. In this comment, we clarify these inaccuracies and also generate conservation laws for a potential form of the underlying equation through Noether theorem.

We give a comprehensive account of Chern's Theorem that S^6 admits no omega-compatible almost complex structures. No claim to originality is being made, as the paper is mostly an expanded version of material already in the literature. This article extends the talks that both authors gave in Marburg during the conference "(Non)existence of complex structures on S^6" in April 2017., Misprints corrected

In this short review note we show that the new proof of theorem 1.1 given by Zheng Jie Sun and Ling Zhu in the paper Simple proofs of the Cusa-Huygens-type and Becker-Stark-type inequalities is logically incorrect and present another simple proof of the same.

In this short note, we show that Theorem 4.3 of Liu and Yu (Monatshefte Math 195:173–176, 2021) is a consequence of Lemma 2 of Ballester-Bolinches and Esteban-Romero (J Aust Math Soc 75:181–191, 2003).

This American College of Physicians position paper, initiated and written by its Health and Public Policy Committee and approved by the Board of Regents on 16 February 2016, reports policy recommendations from the American College of Physicians to address the escalating costs of prescription drugs in the United States. Prescription drugs play an important part in treating and preventing disease. However, the United States often pays more for some prescription drugs than other developed countries, and the high price and increasing costs associated with prescription medication is a major concern for patients, physicians, and payers. Pharmaceutical companies have considerable flexibility in how they price drugs, and the costs that payers and patients see are dependent on how payers are able to negotiate discounts or rebates. Beyond setting list prices are issues of regulatory approval, patents and intellectual property, assessment of value and cost-effectiveness, and health plan drug benefits. These issues are linked, and comprehensive efforts will be needed to affect how drugs are priced in the United States.

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has revolutionized the practice of ambulatory medicine, triggering rapid dissemination of digital healthcare modalities, including synchronous video visits. However, social determinants of health, such as age, race, income, and others, predict readiness for telemedicine and individuals who are not able to connect virtually may become lost to care. This is particularly relevant to the practice of infectious diseases (ID) and human immunodeficiency virus (HIV) medicine, as we care for high proportions of individuals whose health outcomes are affected by such factors. Furthermore, delivering high-quality clinical care in ID and HIV practice necessitates discussion of sensitive topics, which is challenging over video without proper preparation. We describe the “digital divide,” emphasize the relevance to ID and HIV practice, underscore the need to study the issue and develop interventions to mitigate its impact, and provide suggestions for optimizing telemedicine in ID and HIV clinics.

The field of Quantitative Information Flow (QIF) is concerned with quantifying information leakage in systems. This work generalises the QIF framework to the quantum setting, having as foundations the recently developed g-leakage framework. Next, some recent results of the field of quantum statistical decision are presented and translated in terms of the "quantum" g-leakage framework, including a recently developed quantum generalisation of the Coriasceous Theorem, an important result for QIF.

These notes aim to provide a deeper insight on the specifics of two articles dealing with chemotaxis models with nonlinear production. More precisely, we are referring to the papers “Boundedness of solutions to a quasilinear parabolic–parabolic chemotaxis model with nonlinear signal production” by Tao et al. (2019) [2] and “Boundedness for a fully parabolic Keller–Segel model with sublinear segregation and superlinear aggregation” by Frassu and Viglialoro (2021) [1] . These works, independently published in these last years, present results leaving open room for further improvement. Indeed, in the first a gap in the proof of the main claim appears, whereas the cornerstone assumption in the second is not sharp. In these pages we give a more complete picture to the relative underlying comprehension.

We thank Holger Rootzen and Dmitrii Zholud’s for their stimulating work, that led us to further investigate the problem of best fitting the human life span distribution. Their assertion “human life is unlimited but short” is based on their conclusion that the exponential model is the best to fit. We provide results based on standard Extreme Value approaches, the Block Maxima and Peaks-over-Threshold, and on the whole data available in the IDL database (IDL A, B validations and GRG). We verify that negative values for the extreme value index are more likely, supporting the conclusion that models with finite endpoint seem better to fit to the human life span distribution.

O. Einstein (2008) proved Bollob\'as-type theorems on intersecting families of ordered sets of finite sets and subspaces. Unfortunately, we report that the proof of a theorem on ordered sets of subspaces had a mistake. We prove two weaker variants., Comment: 6 pages. Improved bound for Theorem 4

International audience; This survey was written by students of L. D. Faddeev under the editorship of L. A. Takhtajan. Sections 1.1, 1.2, 2–4, and 6 were written by Takhtajan, §§1.3 and 1.4 by F. A. Smirnov, §§5.1 and 5.2 by E. K. Sklyanin, §§5.3–5.6 by Sklyanin, Smirnov, and Takhtajan, §7.1 by M. A. Semenov- Tian-Shansky, §§7.2–7.6 by Takhtajan and S. L. Shatashvili, §7.7 by A. Yu. Alekseev and Shatashvili, and §8 by I. Ya. Aref'eva.

The translation into English of Aleksandr Yakovlevich Khinchin's (1894–1959) 1926 paper entitled ‘Ideas of intuitionism and the struggle for a subject matter in contemporary mathematics’ is made available for the first time. Here, Khinchin presented the famous foundational debate between L.E.J. Brouwer and David Hilbert of the 1920s in terms of a search for a mathematics with content. His main aim seems to have been to make intuitionism ideologically acceptable to his audience at the Communist Academy by means of the claim that insofar as Brouwer's intuitionism had a clear ‘subject matter’ and Hilbert's new program was a concession to intuitionism, the alleged victory of intuitionism not only implied the defeat of ‘empty’ formalism, but also showed the compatibility and affinity of Marxism with the newest developments in modern mathematics. This introduction provides a tentative exploration of the issue of what was tactical (or due to ideological pressure) and what was real scientific interest (or due to ignorance) (or what was both) in Khinchin's 1926 paper in the form of a detailed commentary, especially, on the tactical side of his presentation of the positions of Brouwer and Hilbert.