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Introduction: This study aimed to assess the analgesic efficacy of oxycodone at doses of 10 mg and 20 mg in dressings after surgery of burn wounds. Material and Methods: Twenty adult patients who underwent surgical treatment of third-degree burn wounds under general anaesthesia were included. Burn wounds were treated with dressings, to which oxycodone was added at 20 mg in Group 1 and 10 mg in Group 2. After the surgery, plasma oxycodone and noroxycodone concentrations were assayed, and pain intensity was assessed with Numerical Rating Scale (NRS). Results: In Group 1, no patient reported pain; in Group 2, four patients reported pain. The pain intensity, according to NRS, was 1–8. Plasma concentration of oxycodone in the blood serum was in the range of 1.24–3.15 ng/mL and 1.09–1.28 ng/mL in Group 1 and Group 2, respectively. Noroxycodone was not detected in the plasma. Adverse effects were not observed in any of the treated patients. Conclusions: Oxycodone in dressings provides patients with adequate and safe analgesia. [ABSTRACT FROM AUTHOR]

Background: The drive for patients to be actively involved in their own healthcare received significant attention during the COVID-19 pandemic. For patients living with wounds, shared care usually encompasses aspects of care planning, and wound care tasks, but the suddenness of the pandemic meant many patients were unsure how to do this sufficiently. Objectives: The aim of this project was to explore experiences of shared wound care during a pandemic from a patient and healthcare professional perspective. Methods: Semi-structured qualitative interviews were undertaken with 25 patients living with wounds and five informal carers. A healthcare professional focus group (n=5) explored experiences of providing shared care information to patients. Thematic analysis was used to analyse the data. Results: The patient and carer interviews revealed five main themes (explanation of wound and wound type; access to healthcare services and the impact of the COVID-19 pandemic; wound education; patient and carer involvement in shared care tasks; the type of wound education that would be most helpful) and eight subthemes. The healthcare professional focus group revealed three main themes (patients who could be involved in shared care; trust education and standardising guidance; supporting people to share care) and five subthemes. Conclusions: This study has highlighted the importance of targeted education for patients living with wounds and their informal carers. Standardising education and guidance for healthcare professional is important to build confidence. Early patient engagement in shared care and personalised care plans are key to maximise acceptance. [ABSTRACT FROM AUTHOR]

Skin tears are traumatic acute wounds that continue to increase with the aging population and the associated physiological skin changes. They are known to cause significant pain, affect quality of life of patients and lead to large amounts of unscheduled and scheduled visits for the district nurses, as well as inappropriate call outs for the paramedics. These type of wounds occur mainly on the arms and legs, they are both preventable and respond well to early intervention. South Warwickshire Foundation Trust TVN's started a three month project, where residential homes carers would be taught how to prevent and manage skin tears, only referring to the district nurses if the wound developed complications. Documentation including care plans and a skin tear first aid box were provided to each home. The project resulted in 93% of all skin tears managed from injury to healing by the residential home. Improving the resident's quality of life, empowering residential home staff, reducing unscheduled and scheduled referrals into the district nurses and callout for paramedics. The project is now being rolled out to all care homes across South Warwickshire Foundation Trust. [ABSTRACT FROM AUTHOR]

Objective: Impaired wound healing can lead to hard-to-heal wounds, which impact on patients, clinicians and healthcare systems. Negative pressure wound therapy with instillation and dwell time (NPWTi-d) was developed to manage wounds through early-stage cleansing. This study describes the use of NPWTi-d to help manage hard-to-heal wounds in patients with risk factors for impaired wound healing. Method: In this case series, patients were treated between October 2015 and March 2018 at a community hospital in western France. Normal saline solution was instilled into wounds with a dwell time of 10 minutes, followed by the application of negative pressure at −75 mmHg to −125 mmHg for 2–3 hours. If needed, patients were given appropriate oral or intravenous antibiotic treatment in conjunction with NPWTi-d and subsequent wound therapies. Results: A total of 15 patients participated in the study. Mean age was 81±13 years, and 12 (80%) patients were malnourished with blood albumin levels of 30.1±5.7g/l, and 12 (80%) patients were given antibiotic therapy. The mean duration of NPWTi-d was 19.4±20.8 days, with a mean number of dressing changes of 6.6±6.8; the duration of NPWTi-d and the number of dressing changes for pressure ulcers was three times that of the other wound types. The mean cost of NPWTi-d in this study was €1643.40±€1709.13. Overall, NPWTi-d provided early-stage wound cleansing and helped achieve adequate granulation tissue formation and progression to the next phase of wound healing. Conclusion: In these cases, NPWTi-d was a beneficial and effective method of treating hard-to-heal wounds that were resistant to traditional treatments, yielding favourable clinical outcomes. [ABSTRACT FROM AUTHOR]

Microbial resistant is one of the problem which impose health costs and other problematical issues considerably. Using of Ag nano-particles as alternate healing method would be good due to its beneficial aspects, especially in wound dressing. In case series study, 160 patients with wound were recruited and divided into two subgroups randomly including 80 patients (13 females, 67 males, mean age= 31.29±9.28) as Agicoat users for their wound and 80 routine prescribed antibiotic patients (11 females, 69 males, mean age= 30.48±8.43). Clinical features of both group were collected meticulously and treatment outcomes were evaluated after 5 and 10 days of start healing methods. The findings were analyzed by SPSS ver.16. Our findings showed that treatment outcomes in Agicoat group were better than that of in antibiotic users' groups. Furthermore, average time of sutures in Agicoat nano-crystal was noticeably less than in antibiotic using group. Moreover, wound length and severity of contamination had direct relationship in wound healing. Also, our assessments revealed that method of treatment are really pivotal in time and power of wound healing (Using of Agicoat was dramatically better strategy than prescribe antibiotic). Regarding to the beneficial effects of Agicoat, including cost effective and reduce pain level and make fast effect because of using in local site and in touched with microbial agents, and also considering day by day increasing antibiotic resistant worldwide, we believe that Agicoat might be a good candidate for substituting of antibiotic. [ABSTRACT FROM AUTHOR]

Summary: Introduction: Skin rejuvenation procedures have become common with sophisticated technologies with reduced downtime and related risks. Recently, microneedling has been paired with radiofrequency to create Fractional Radiofrequency Microneedling (FRFM) to induce neocollagenesis. Frequently, topical products are applied immediately after the needling. This procedure is known as percutaneous collagen induction therapy (PCIT). Postoperative topical wound care is critical for prompt rapid and safe healing, with moist wound healing deemed of primary importance for fast and correct scarring process. An ideal dressing enables a moist environment while reducing postprocedural inflammatory responses in the first stages of wound healing. Objective: To evaluate whether an innovative silicone‐based wound dressing is superior than standard of care therapy in decreasing severity and duration of treatment‐site acute inflammatory reactions post PCIT. Materials and Methods: Endymed PRO Intensif Handpiece (Endymed, Israel) was used for the full‐face FRFM procedure. Subjects (n = 20) applied treatment (Stratacel®—Stratpharma SG, Switzerland) and control (Aquaphor®—Beiersdorf Inc, USA) immediately after the procedure and daily; they were evaluated immediately postprocedure (baseline assessment), at 2, 3 and 7 days postprocedure. Digital and 3D pictures (Antera 3D Camera for Skin Analysis—Miravex, Ireland) were taken at each assessment. Results: All patients healed properly without reporting adverse reactions to any of the studied products. Erythema at each study visit was significantly reduced with the use of the novel wound dressing (P < 0.001). A statistically significant difference in favor of the innovative wound dressing also emerged with respect to the patient‐rated product properties (P = 0.008), such as feel on skin, drying time and stickiness. Conclusions: The novel wound dressing reduced signs of acute inflammation following PCIT when compared to standard of care, without reporting adverse events and resulting in a more favorable outcome from a patient perspective. [ABSTRACT FROM AUTHOR]

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Skin tears are frequently encountered in emergency and unscheduled care, and are prevalent in older people. Patients may present soon after an acute skin tear, or at a later stage when the wound presentation is different and there are complications. This article describes evidence-based recommendations and strategies for the prevention, assessment and management of skin tears, discusses risk factors and explains when to refer patients for specialist management. [ABSTRACT FROM AUTHOR]

Epidermolysis Bullosa (EB) is a rare genetic skin disorder characterised by fragility and blistering of skin and mucous membranes. Skin can blister and shear away from minimal friction, trauma and every day activities. The disease causes a wide range of complications but wound care is the major challenge to severe EB, and good wound care is an essential part of wound management. The goal of wound care was to choose a product that protects the fragile skin, limits friction, decreases pain and promotes healing. However, access to wound dressings for those people living with EB is challenging. This article discusses the availability of EB dressings in a number of countries around the world and also describes an innovative National Epidermolysis Bullosa Dressings Scheme (NEBDS) in Australia, which aims to improve the quality of life of people with EB, by reducing the financial burden associated with the provision of dressings accordingly. [ABSTRACT FROM AUTHOR]